Detailed information for compound 416670

Basic information

Technical information
  • TDR Targets ID: 416670
  • Name: [4-(3-fluoro-4-methoxyphenyl)-2-oxo-3-(3,4,5- trimethoxyphenyl)cyclopent-3-en-1-yl] acetate
  • MW: 430.423 | Formula: C23H23FO7
  • H donors: 0 H acceptors: 2 LogP: 3.36 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(cc(c1OC)OC)C1=C(CC(C1=O)OC(=O)C)c1ccc(c(c1)F)OC
  • InChi: 1S/C23H23FO7/c1-12(25)31-18-11-15(13-6-7-17(27-2)16(24)8-13)21(22(18)26)14-9-19(28-3)23(30-5)20(10-14)29-4/h6-10,18H,11H2,1-5H3
  • InChiKey: IULHHVPKZSFIPY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [4-(3-fluoro-4-methoxy-phenyl)-2-oxo-3-(3,4,5-trimethoxyphenyl)cyclopent-3-en-1-yl] acetate
  • acetic acid [4-(3-fluoro-4-methoxyphenyl)-2-oxo-3-(3,4,5-trimethoxyphenyl)-1-cyclopent-3-enyl] ester
  • [4-(3-fluoro-4-methoxy-phenyl)-2-oxo-3-(3,4,5-trimethoxyphenyl)cyclopent-3-en-1-yl] ethanoate
  • acetic acid [4-(3-fluoro-4-methoxy-phenyl)-2-keto-3-(3,4,5-trimethoxyphenyl)cyclopent-3-en-1-yl] ester
  • [4-(3-fluoro-4-methoxyphenyl)-2-oxo-3-(3,4,5-trimethoxyphenyl)-1-cyclopent-3-enyl] acetate
  • [4-(3-fluoro-4-methoxy-phenyl)-2-oxo-3-(3,4,5-trimethoxyphenyl)-1-cyclopent-3-enyl] acetate
  • acetic acid [4-(3-fluoro-4-methoxy-phenyl)-2-keto-3-(3,4,5-trimethoxyphenyl)-1-cyclopent-3-enyl] ester
  • [4-(3-fluoro-4-methoxy-phenyl)-2-oxo-3-(3,4,5-trimethoxyphenyl)-1-cyclopent-3-enyl] ethanoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0099 0.0389 0.0483
Schistosoma mansoni adapter molecule crk 0.0099 0.0386 0.0555
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0847 0.1297
Schistosoma mansoni rap gtpase-activating protein 0.0112 0.0522 0.0774
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0106 0.046 0.0754
Echinococcus granulosus cyclin dependent kinase 0.0124 0.0642 0.066
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0584 0.0499
Brugia malayi Protein kinase domain containing protein 0.0098 0.0384 0.0321
Loa Loa (eye worm) hypothetical protein 0.0099 0.0393 0.0393
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0096 0.0355 0.0327
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0148 0.0882 0.1096
Onchocerca volvulus 0.0106 0.0463 0.0852
Entamoeba histolytica hypothetical protein 0.0096 0.0355 0.0268
Loa Loa (eye worm) hypothetical protein 0.0119 0.0595 0.0595
Echinococcus granulosus Vam6:Vps39 protein 0.0112 0.0522 0.0536
Schistosoma mansoni serine/threonine-protein kinase 0.0679 0.6259 1
Schistosoma mansoni nck2/grb4 0.0099 0.0386 0.0555
Onchocerca volvulus 0.0075 0.015 0.0226
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0095 0.0344 0.0344
Giardia lamblia Kinase, CMGC GSK 0.0134 0.0742 0.0857
Brugia malayi probable protein kinase 0.0271 0.2125 0.2073
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0455 0.3988 0.3988
Loa Loa (eye worm) hypothetical protein 0.0139 0.0796 0.0796
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0151 0.0913 0.1557
Entamoeba histolytica cell division protein kinase 2, putative 0.0124 0.0642 0.0558
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0147 0.088 0.135
Plasmodium falciparum NIMA related kinase 1 0.0141 0.0818 0.1033
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0384 0.0297
Brugia malayi Protein kinase domain containing protein 0.095 0.8995 0.8988
Trichomonas vaginalis CK1 family protein kinase 0.0114 0.0539 0.0454
Brugia malayi protein kinase C3,putative 0.0163 0.1037 0.0979
Schistosoma mansoni serine/threonine protein kinase 0.0538 0.4828 0.7699
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0151 0.0913 0.0831
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0607 0.5525 0.5525
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0098 0.0384 0.0373
Trichomonas vaginalis CK1 family protein kinase 0.0114 0.0539 0.0454
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0106 0.046 0.0398
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0415 0.3587 0.3683
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0112 0.0522 0.0774
Schistosoma mansoni serine/threonine protein kinase 0.0408 0.3512 0.5583
Schistosoma mansoni titin 0.0075 0.015 0.0177
Echinococcus granulosus expressed protein 0.0088 0.028 0.0288
Echinococcus multilocularis Glutaredoxin protein 5 0.0584 0.5291 0.6577
Giardia lamblia Kinase, CK1 Casein kinase 0.0114 0.0539 0.0481
Trypanosoma cruzi cdc2-related kinase 3 0.0124 0.0642 0.0797
Schistosoma mansoni tyrosine kinase 0.0089 0.0287 0.0397
Brugia malayi hypothetical protein 0.0099 0.0393 0.0331
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0088 0.028 0.0023
Echinococcus granulosus mitogen activated protein kinase 0.0089 0.0286 0.0294
Toxoplasma gondii aurora kinase 0.0151 0.0913 0.0714
Echinococcus granulosus serine:threonine protein kinase N2 0.0538 0.4828 0.4957
Loa Loa (eye worm) AUR protein kinase 0.0151 0.0913 0.0913
Brugia malayi Egg laying defective protein 4 0.014 0.0803 0.0743
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0106 0.0463 0.0377
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Trypanosoma cruzi NIMA-related kinase, putative 0.0096 0.0355 0.0327
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0463 0.0463
Echinococcus multilocularis calcium activated potassium channel 0.014 0.0805 0.1001
Plasmodium falciparum serine/threonine protein kinase 0.0088 0.028 0.0039
Echinococcus granulosus casein kinase I alpha 0.0114 0.0539 0.0554
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1023 0.9739 1
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0124 0.0642 0.0642
Echinococcus multilocularis mitogen activated protein kinase 14 0.0164 0.1051 0.1307
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0087 0.0264 0.0271
Loa Loa (eye worm) thyroid receptor interactor 0.0117 0.0575 0.0575
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0087 0.0264 0.0264
Echinococcus granulosus tyrosine protein kinase Fyn 0.0236 0.1772 0.182
Schistosoma mansoni protein kinase 0.0091 0.031 0.0433
Trichomonas vaginalis CMGC family protein kinase 0.0095 0.0348 0.026
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Echinococcus multilocularis serine:threonine protein kinase N2 0.0538 0.4828 0.6001
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0118 0.0584 0.0327
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.009 0.0296 0.0032
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0991 0.9416 0.9416
Onchocerca volvulus 0.0106 0.0463 0.0852
Brugia malayi Protein kinase domain containing protein 0.0106 0.0463 0.0401
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.008 0.02 0.0206
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0468 0.4124 0.4235
Echinococcus multilocularis Immunoglobulin 0.0084 0.0234 0.0291
Loa Loa (eye worm) hypothetical protein 0.0181 0.122 0.122
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0112 0.0522 0.0774
Brugia malayi Doublecortin family protein 0.0156 0.0967 0.0908
Echinococcus multilocularis serine:threonine protein kinase 0.0119 0.0595 0.0739
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.0642 0.0968
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0236 0.1772 0.2203
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0095 0.0344 0.0428
Brugia malayi Variant SH3 domain containing protein 0.0099 0.0386 0.0323
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0191 0.1322 0.1266
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0127 0.0677 0.2153
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0116 0.0563 0.0477
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0584 0.0874
Giardia lamblia Kinase, CAMK CAMKL 0.0095 0.0344 0.0118
Echinococcus granulosus tyrosine protein kinase 0.0289 0.2314 0.2376
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0348 0.0494
Brugia malayi protein-tyrosine kinase 0.0194 0.1355 0.1299
Brugia malayi serine/threonine protein kinase 6 0.0151 0.0913 0.0854
Echinococcus multilocularis mitogen activated protein kinase 11 0.0164 0.1051 0.1307
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0621 0.5675 0.7054
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0106 0.046 0.0754
Loa Loa (eye worm) AUR protein kinase 0.0151 0.0913 0.0913
Plasmodium falciparum protein kinase, putative 0.0087 0.0265 0.0012
Brugia malayi SH2 domain containing protein 0.0106 0.0463 0.0401
Trypanosoma brucei protein kinase, putative 0.0134 0.0742 0.049
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0158 0.0991 0.0991
Loa Loa (eye worm) hypothetical protein 0.0084 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0463 0.407 0.407
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0127 0.0677 0.0677
Giardia lamblia Aurora kinase 0.0151 0.0913 0.1173
Schistosoma mansoni tyrosine kinase 0.0236 0.1772 0.2785
Onchocerca volvulus 0.0139 0.0796 0.1519
Schistosoma mansoni hypothetical protein 0.0102 0.0422 0.0613
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Echinococcus granulosus protein tyrosine kinase 0.0556 0.5017 0.5152
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0124 0.0642 0.1971
Trichomonas vaginalis CAMK family protein kinase 0.0276 0.2179 0.2109
Schistosoma mansoni protein kinase 0.0373 0.3158 0.5014
Brugia malayi SH2 domain containing protein 0.0411 0.3541 0.3499
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0118 0.0584 0.0701
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0091 0.031 0.0318
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0262 0.2043 0.2043
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0607 0.5525 0.5525
Schistosoma mansoni growth factor receptor-bound protein 0.0099 0.0386 0.0555
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0233 0.1741 0.1788
Brugia malayi Stress-activated protein kinase jnk-1 0.027 0.2118 0.2067
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0286 0.0396
Entamoeba histolytica PH domain containing protein kinase, putative 0.0679 0.6259 0.6225
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Echinococcus multilocularis casein kinase I alpha 0.0114 0.0539 0.067
Loa Loa (eye worm) hypothetical protein 0.0099 0.0393 0.0393
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0501 0.4453 0.5535
Onchocerca volvulus 0.0487 0.4316 0.857
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0169 0.1102 0.137
Echinococcus multilocularis mitogen activated protein kinase 3 0.0089 0.0286 0.0356
Schistosoma mansoni tyrosine kinase 0.0358 0.3009 0.4773
Echinococcus granulosus casein kinase I alpha 0.0114 0.0539 0.0554
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0373 0.3158 0.3243
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0358 0.3014 0.3747
Brugia malayi Sex muscle abnormal protein 5 0.0099 0.0386 0.0323
Giardia lamblia Kinase, NEK 0.0141 0.0818 0.0998
Trichomonas vaginalis AGC family protein kinase 0.1049 1 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0214 0.0214
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0286 0.0199
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0096 0.0355 0.0093
Echinococcus granulosus c-Jun N-terminal kinases 0.027 0.2118 0.2175
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0803 0.1225
Echinococcus granulosus dual specificity 0.0144 0.0847 0.087
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0306 0.0427
Brugia malayi Protein kinase domain containing protein 0.0452 0.3965 0.3926
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0134 0.0742 0.0742
Echinococcus granulosus protein kinase c epsilon type 0.0451 0.3949 0.4055
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.009 0.0296 0.0229
Loa Loa (eye worm) hypothetical protein 0.0547 0.492 0.492
Loa Loa (eye worm) hypothetical protein 0.0064 0.0037 0.0037
Echinococcus granulosus serine:threonine kinase SAD 1 0.0095 0.0344 0.0353
Echinococcus multilocularis cyclin dependent kinase 1 0.0124 0.0642 0.0798
Entamoeba histolytica protein kinase domain containing protein 0.0087 0.0265 0.0177
Entamoeba histolytica serine/threonine protein kinase, putative 0.0095 0.0344 0.0257
Schistosoma mansoni serine/threonine protein kinase 0.0483 0.4277 0.6812
Trichomonas vaginalis CAMK family protein kinase 0.0276 0.2179 0.2109
Loa Loa (eye worm) TK/INSR protein kinase 0.0452 0.3965 0.3965
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0127 0.0677 0.0423
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0208 0.1493 0.1493
Entamoeba histolytica protein kinase, putative 0.0144 0.0847 0.0764
Schistosoma mansoni tyrosine kinase 0.0248 0.1893 0.2979
Toxoplasma gondii CMGC kinase, CK2 family 0.0105 0.0453 0.0212
Entamoeba histolytica protein kinase, putative 0.0127 0.0674 0.0589
Loa Loa (eye worm) hypothetical protein 0.0144 0.0844 0.0844
Trichomonas vaginalis STE family protein kinase 0.0091 0.031 0.0222
Plasmodium falciparum calcium-dependent protein kinase 4 0.0106 0.046 0.0372
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0095 0.0344 0.0308
Echinococcus multilocularis insulin receptor 0.0452 0.3965 0.4929
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0151 0.0913 0.0831
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.014 0.0803 0.0594
Echinococcus granulosus NCK adaptor protein 0.0099 0.0386 0.0396
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0408 0.3512 0.3606
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0144 0.0847 0.0642
Echinococcus multilocularis raf serine:threonine protein kinase 0.0091 0.0306 0.038
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0096 0.0355 0.0327
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0491 0.4352 0.5409
Echinococcus granulosus raf serine:threonine protein kinase 0.0091 0.0306 0.0314
Brugia malayi C1-like domain containing protein 0.0223 0.1645 0.1591
Echinococcus granulosus Protein kinase C brain isozyme 0.0491 0.4352 0.4468
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0098 0.0384 0.0136
Giardia lamblia Kinase, AGC AKT 0.0122 0.0625 0.0639
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0095 0.0344 0.0081
Echinococcus granulosus c src tyrosine kinase 0.0147 0.088 0.0903
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Echinococcus granulosus insulin receptor 0.0452 0.3965 0.4072
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0089 0.0286 0.0214
Echinococcus granulosus growth factor receptor bound protein 2 0.0101 0.0406 0.0417
Echinococcus multilocularis protein kinase shaggy 0.0134 0.0742 0.0923
Entamoeba histolytica protein kinase, putative 0.1049 1 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0176 0.1168 0.1088
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0076 0.0156 0.0193
Entamoeba histolytica cell division protein kinase 2, putative 0.0124 0.0642 0.0558
Schistosoma mansoni tyrosine kinase 0.0147 0.088 0.135
Entamoeba histolytica protein kinase, putative 0.0088 0.028 0.0192
Echinococcus multilocularis neuroglian 0.0105 0.0454 0.0565
Loa Loa (eye worm) hypothetical protein 0.01 0.0396 0.0396
Schistosoma mansoni serine/threonine-protein kinase 0.0679 0.6259 1
Loa Loa (eye worm) hypothetical protein 0.0128 0.0686 0.0686
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0112 0.0522 0.0648
Echinococcus granulosus roundabout 2 0.014 0.0799 0.082
Echinococcus granulosus casein kinase I alpha 0.0114 0.0539 0.0554
Echinococcus granulosus pdz domain containing protein 0.0073 0.0125 0.0128
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0106 0.046 0.0572
Echinococcus multilocularis casein kinase ii subunit alpha 0.0105 0.0453 0.0563
Plasmodium vivax casein kinase 1, putative 0.0114 0.0539 0.0895
Loa Loa (eye worm) hypothetical protein 0.0102 0.042 0.042
Schistosoma mansoni tyrosine kinase 0.008 0.02 0.0256
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.046 0.0675
Trypanosoma cruzi casein kinase, putative 0.0114 0.0539 0.0628
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0099 0.0386 0.0386
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0238 0.1792 0.1792
Mycobacterium ulcerans hypothetical protein 0.0102 0.0419 0.5
Trichomonas vaginalis AGC family protein kinase 0.0141 0.0818 0.0735
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0099 0.0386 0.0386
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0134 0.0742 0.1129
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0621 0.5675 0.9043
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0411 0.3541 0.3636
Entamoeba histolytica PH domain containing protein kinase, putative 0.0176 0.1168 0.1088
Trypanosoma brucei polo-like protein kinase 0.0276 0.2179 0.1966
Brugia malayi Casein kinase II, alpha chain 0.0105 0.0453 0.0391
Echinococcus multilocularis casein kinase I gamma 0.0219 0.16 0.1989
Echinococcus granulosus tyrosine protein kinase Src64B 0.0236 0.1772 0.182
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0415 0.3587 0.4458
Leishmania major casein kinase II, putative 0.0105 0.0453 0.098
Echinococcus granulosus tyrosine protein kinase ABL1 0.0314 0.2567 0.2636
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0228 0.1692 0.1737
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Echinococcus granulosus fibroblast growth factor receptor 4 0.0248 0.1893 0.1944
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0151 0.0913 0.1135
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0236 0.1772 0.2203
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0151 0.0913 0.0938
Trichomonas vaginalis AGC family protein kinase 0.0428 0.372 0.3663
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0118 0.0584 0.0599
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.1102 0.1707
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0099 0.0393 0.0567
Trypanosoma cruzi NIMA-related kinase, putative 0.0096 0.0355 0.0327
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0164 0.1051 0.4108
Onchocerca volvulus 0.0243 0.1845 0.3621
Plasmodium falciparum glycogen synthase kinase 3 0.0134 0.0742 0.0893
Loa Loa (eye worm) hypothetical protein 0.0112 0.0522 0.0522
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0206 0.1474 0.1513
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0118 0.0584 0.0599
Echinococcus granulosus neuroglian 0.0105 0.0454 0.0467
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0118 0.0584 0.0327
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Giardia lamblia Kinase, CMGC GSK 0.0134 0.0742 0.0857
Schistosoma mansoni protein kinase 0.044 0.384 0.611
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.0847 0.0764
Loa Loa (eye worm) CAMK protein kinase 0.0075 0.015 0.015
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0407 0.3503 0.3596
Plasmodium vivax tyrosine kinase-like protein, putative 0.0086 0.0259 0.0397
Echinococcus granulosus activin receptor type 0.0087 0.0265 0.0272
Schistosoma mansoni tyrosine kinase 0.0257 0.1986 0.3129
Loa Loa (eye worm) TK/FAK protein kinase 0.0562 0.5078 0.5078
Leishmania major protein kinase, putative 0.0096 0.0355 0.0471
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0118 0.0584 0.0701
Echinococcus multilocularis N chimaerin 0.0099 0.0393 0.0489
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0134 0.0742 0.2494
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0913 0.1403
Loa Loa (eye worm) hypothetical protein 0.009 0.0294 0.0294
Brugia malayi serine/threonine-protein kinase PAK 7 0.0238 0.1792 0.1738
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0453 0.0366
Toxoplasma gondii protein kinase domain-containing protein 0.0096 0.0355 0.0105
Brugia malayi Protein kinase domain containing protein 0.0198 0.1393 0.1337
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.009 0.0296 0.0208
Echinococcus granulosus dual specificity 0.0144 0.0847 0.087
Onchocerca volvulus Serine\/threonine kinase homolog 0.0276 0.2179 0.429
Loa Loa (eye worm) TK/EPH protein kinase 0.0131 0.0709 0.0709
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0276 0.2179 1
Giardia lamblia Kinase, CMGC CLK 0.0098 0.0384 0.0192
Loa Loa (eye worm) hypothetical protein 0.009 0.0294 0.0294
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0087 0.0265 0.0179
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0089 0.0286 0.0112
Loa Loa (eye worm) hypothetical protein 0.0143 0.0837 0.0837
Echinococcus granulosus defective proboscis extension response 0.0084 0.0234 0.0241
Trypanosoma brucei SNF1-related protein kinases, putative 0.0095 0.0344 0.0081
Onchocerca volvulus 0.0076 0.0156 0.0237
Brugia malayi putative serine/threonine kinase SADA gamma 0.0095 0.0344 0.0281
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0091 0.031 0.0385
Brugia malayi map kinase activated protein kinase protein 2 0.04 0.3437 0.3394
Echinococcus multilocularis protein kinase c epsilon type 0.0451 0.3949 0.4909
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0076 0.0156 0.016
Trypanosoma brucei cdc2-related kinase 1 0.0124 0.0642 0.0387
Brugia malayi Protein kinase domain 0.0091 0.031 0.0247
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0089 0.0286 0.003
Echinococcus multilocularis activin receptor type 0.0087 0.0265 0.033
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0264 0.0176
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0096 0.0355 0.0327
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0223 0.1645 0.1645
Loa Loa (eye worm) hypothetical protein 0.0607 0.5525 0.5525
Loa Loa (eye worm) hypothetical protein 0.0086 0.0259 0.0259
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0096 0.0355 0.0093
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0492 0.4366 0.4483
Brugia malayi Protein kinase domain containing protein 0.0607 0.5525 0.5496
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0098 0.0384 0.0122
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0248 0.1893 0.2353
Trichomonas vaginalis CMGC family protein kinase 0.0095 0.0348 0.026
Brugia malayi Protein kinase domain containing protein 0.0095 0.0348 0.0285
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0144 0.0847 0.0847
Echinococcus multilocularis tyrosine protein kinase 0.0289 0.2314 0.2877
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0194 0.1355 0.1392
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0089 0.0286 0.0214
Trichomonas vaginalis AGC family protein kinase 0.1049 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0124 0.0642 0.0558
Entamoeba histolytica casein kinase, putative 0.0114 0.0539 0.0454
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0358 0.3014 0.2969
Brugia malayi intracellular kinase 0.0134 0.0742 0.0682
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0194 0.1355 0.1685
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.1692 0.2655
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0106 0.046 0.0472
Echinococcus multilocularis serine:threonine protein kinase N2 0.013 0.0703 0.0874
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0118 0.0584 0.0599
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0099 0.0389 0.0399
Echinococcus multilocularis epidermal growth factor receptor 0.0616 0.5615 0.6979
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Trichomonas vaginalis AGC family protein kinase 0.1049 1 1
Trichomonas vaginalis CAMK family protein kinase 0.012 0.0605 0.052
Echinococcus granulosus calcium dependent protein kinase 0.0068 0.0077 0.0079
Brugia malayi Protein kinase domain containing protein 0.0199 0.1403 0.1347
Echinococcus granulosus serine:threonine protein kinase 3 0.0262 0.2043 0.2098
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0096 0.0355 0.0327
Loa Loa (eye worm) AUR protein kinase 0.0151 0.0913 0.0913
Trypanosoma cruzi aurora B kinase, putative 0.0151 0.0913 0.1241
Echinococcus multilocularis nervana 2 0.0584 0.5291 0.6577
Echinococcus granulosus casein kinase i 0.0114 0.0539 0.0554
Leishmania major protein kinase A catalytic subunit isoform 1 0.0118 0.0584 0.1664
Entamoeba histolytica protein kinase, putative 0.0107 0.0473 0.0387
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0124 0.0642 0.0642
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0116 0.0563 0.0477
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0222 0.1638 0.1638
Loa Loa (eye worm) hypothetical protein 0.0084 0.0237 0.0237
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0373 0.3158 0.3926
Trichomonas vaginalis CK1 family protein kinase 0.0114 0.0539 0.0454
Loa Loa (eye worm) hypothetical protein 0.0112 0.0522 0.0522
Loa Loa (eye worm) hypothetical protein 0.0124 0.064 0.064
Brugia malayi STE20-like kinase MST 0.0262 0.2043 0.1991
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0355 0.0268
Giardia lamblia Kinase, NEK 0.0141 0.0818 0.0998
Entamoeba histolytica PH domain containing protein kinase, putative 0.0679 0.6259 0.6225
Trichomonas vaginalis CAMK family protein kinase 0.0276 0.2179 0.2109
Brugia malayi Protein kinase c protein 2 0.0121 0.0611 0.055
Echinococcus multilocularis 0.0158 0.0991 0.1232
Brugia malayi Variant SH3 domain containing protein 0.0099 0.0386 0.0323
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0098 0.0384 0.0373
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0098 0.0384 0.0122
Brugia malayi P38 map kinase family protein 2 0.0164 0.1051 0.0993
Entamoeba histolytica protein kinase, putative 0.0076 0.0156 0.0067
Brugia malayi Tyrosine-protein kinase abl-1 0.0227 0.1684 0.163
Echinococcus multilocularis titin 0.0075 0.015 0.0187
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0106 0.046 0.0572
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0243 0.1843 0.2291
Loa Loa (eye worm) hypothetical protein 0.0102 0.0422 0.0422
Echinococcus multilocularis hypothetical protein 0.0102 0.0422 0.0524
Loa Loa (eye worm) hypothetical protein 0.0243 0.1845 0.1845
Brugia malayi Variant SH3 domain containing protein 0.0116 0.0566 0.0504
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.0847 0.0764
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0355 0.0268
Trypanosoma brucei protein kinase, putative 0.0096 0.0355 0.0093
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.1821 0.2864
Plasmodium falciparum casein kinase 1 0.0114 0.0539 0.0518
Schistosoma mansoni ste20-related kinase 0.0211 0.1518 0.2376
Schistosoma mansoni tyrosine kinase 0.0407 0.3503 0.5567
Plasmodium falciparum cGMP-dependent protein kinase 0.014 0.0803 0.1004
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0076 0.0156 0.0194
Echinococcus granulosus Immunoglobulin 0.0084 0.0234 0.0241
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0091 0.031 0.0318
Toxoplasma gondii AGC kinase 0.0118 0.0584 0.0355
Echinococcus multilocularis myotubularin protein 13 0.01 0.0396 0.0492
Leishmania major serine/threonine-protein kinase a, putative 0.0096 0.0355 0.0471
Echinococcus multilocularis expressed protein 0.0088 0.028 0.0348
Loa Loa (eye worm) hypothetical protein 0.0084 0.0234 0.0234
Loa Loa (eye worm) AGC/PKA protein kinase 0.0118 0.0584 0.0584
Echinococcus granulosus mitogen activated protein kinase 11 0.0164 0.1051 0.108
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0334 0.2767 0.272
Brugia malayi Protein kinase domain containing protein 0.0124 0.0642 0.0581
Schistosoma mansoni protein kinase C mu 0.0223 0.1645 0.258
Trypanosoma brucei protein kinase, putative 0.0089 0.0286 0.0022
Giardia lamblia Kinase, CDC7 0.0095 0.0348 0.0125
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0106 0.046 0.022
Echinococcus multilocularis c src tyrosine kinase 0.0147 0.088 0.1094
Brugia malayi Temporarily assigned gene name protein 59 0.0129 0.0697 0.0636
Giardia lamblia Kinase, STE STE20 0.0091 0.031 0.0055
Entamoeba histolytica hypothetical protein 0.0127 0.0677 0.0593
Echinococcus granulosus serine:threonine protein kinase 0.0119 0.0595 0.0611
Echinococcus multilocularis nervana 2 0.0584 0.5291 0.6577
Entamoeba histolytica protein kinase, putative 0.0096 0.0355 0.0268
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0089 0.0286 0.0112
Trichomonas vaginalis STE family protein kinase 0.0091 0.031 0.0222
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.015 0.0906 0.1127
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Trichomonas vaginalis CMGC family protein kinase 0.0124 0.0642 0.0558
Giardia lamblia Kinase, CAMK CAMKL 0.0095 0.0344 0.0118
Brugia malayi SRC-1 0.0236 0.1772 0.1719
Entamoeba histolytica protein kinase, putative 0.0151 0.0913 0.0831
Leishmania major protein kinase, putative 0.0098 0.0384 0.0619
Plasmodium vivax unspecified product 0.0105 0.0453 0.0741
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Loa Loa (eye worm) TK protein kinase 0.0289 0.2314 0.2314
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.015 0.0177
Echinococcus multilocularis ephrin type A receptor 4 A 0.0113 0.0531 0.066
Brugia malayi Temporarily assigned gene name protein 59 0.0112 0.0522 0.046
Trichomonas vaginalis AGC family protein kinase 0.0151 0.0913 0.0831
Echinococcus multilocularis expressed conserved protein 0.014 0.0803 0.0998
Loa Loa (eye worm) TK/ABL protein kinase 0.0314 0.2567 0.2567
Entamoeba histolytica hypothetical protein 0.0381 0.3244 0.3183
Brugia malayi Protein kinase domain containing protein 0.0127 0.0677 0.0617
Echinococcus multilocularis CDC7 cell division cycle 7 0.0095 0.0348 0.0432
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.0847 0.0764
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0112 0.0522 0.0263
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0677 0.1024
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0141 0.0818 0.0611
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0096 0.0355 0.0327
Echinococcus granulosus epidermal growth factor receptor 0.0616 0.5615 0.5765
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.04 0.3437 0.3437
Echinococcus granulosus tyrosine protein kinase Fyn 0.0236 0.1772 0.182
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0106 0.046 0.0754
Trichomonas vaginalis AGC family protein kinase 0.1049 1 1
Entamoeba histolytica protein kinase, putative 0.0151 0.0913 0.0831
Echinococcus granulosus cyclin dependent kinase 5 0.0124 0.0642 0.066
Onchocerca volvulus 0.0081 0.0209 0.0343
Plasmodium vivax serine/threonine protein kinase, putative 0.0088 0.028 0.0435
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0112 0.0522 0.0599
Brugia malayi Protein kinase domain containing protein 0.0088 0.028 0.0217
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0156 0.0185
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0124 0.0642 0.0419
Entamoeba histolytica protein kinase, putative 0.0095 0.0352 0.0265
Onchocerca volvulus 0.0106 0.0463 0.0852
Echinococcus granulosus nervana 2 0.0584 0.5291 0.5433
Echinococcus multilocularis pdz domain containing protein 0.0073 0.0125 0.0155
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0206 0.1474 0.1474
Schistosoma mansoni serine/threonine kinase 0.0408 0.3512 0.5583
Giardia lamblia Kinase, AGC PKA 0.0621 0.5675 1
Schistosoma mansoni serine/threonine protein kinase 0.0491 0.4352 0.6933
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0169 0.1102 0.1102
Echinococcus multilocularis mitogen activated protein kinase 14 0.0164 0.1051 0.1307
Brugia malayi MAP kinase sur-1 0.0089 0.0286 0.0223
Brugia malayi hypothetical protein 0.0106 0.0463 0.0401
Trichomonas vaginalis STE family protein kinase 0.0091 0.031 0.0222
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0463 0.0463
Trypanosoma cruzi polo-like protein kinase, putative 0.0276 0.2179 0.3315
Loa Loa (eye worm) TK protein kinase 0.0353 0.296 0.296
Schistosoma mansoni kinase 0.0294 0.2366 0.374
Plasmodium falciparum serine/threonine protein kinase KIN 0.0095 0.0344 0.0157
Echinococcus multilocularis tyrosine protein kinase Blk 0.0194 0.1355 0.1685
Echinococcus granulosus MAP kinase activated protein kinase 2 0.04 0.3437 0.3529
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0098 0.0384 0.0373
Trichomonas vaginalis CAMK family protein kinase 0.0276 0.2179 0.2109
Loa Loa (eye worm) CDC7 protein kinase 0.0095 0.0348 0.0348
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Brugia malayi Immunoglobulin I-set domain containing protein 0.0638 0.5842 0.5815
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0373 0.3158 0.3158
Echinococcus granulosus titin 0.0075 0.015 0.0154
Brugia malayi RhoGAP domain containing protein 0.0099 0.0393 0.0331
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Schistosoma mansoni tyrosine kinase 0.0452 0.3965 0.6311
Trichomonas vaginalis AGC family protein kinase 0.0428 0.372 0.3663
Loa Loa (eye worm) hypothetical protein 0.0185 0.1261 0.1261
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0453 0.0366
Brugia malayi Protein kinase domain containing protein 0.0219 0.16 0.1546
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0344 0.0488
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0463 0.0463
Loa Loa (eye worm) TK protein kinase 0.0269 0.2113 0.2113
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0064 0.0033 0.0041
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0084 0.0234 0.0291
Brugia malayi Tyrosine-protein kinase abl-1 0.0128 0.0688 0.0627
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0124 0.0642 0.0642
Echinococcus granulosus cGMP dependent protein kinase 1 0.014 0.0803 0.0824
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.0847 0.0764
Loa Loa (eye worm) AGC/PKA protein kinase 0.0118 0.0584 0.0584
Plasmodium vivax glycogen synthase kinase 3, putative 0.0134 0.0742 0.1255
Giardia lamblia Kinase, PLK 0.0276 0.2179 0.352
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0105 0.0453 0.0453
Loa Loa (eye worm) hypothetical protein 0.0119 0.0595 0.0595
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0236 0.1772 0.2203
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0151 0.0913 0.0831
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0087 0.0265 0.0179
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0106 0.046 0.02
Loa Loa (eye worm) hypothetical protein 0.0115 0.0553 0.0553
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.044 0.384 0.3943
Loa Loa (eye worm) hypothetical protein 0.0139 0.0796 0.0796
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0408 0.3512 0.4366
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0096 0.0355 0.0093
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0453 0.0366
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0084 0.0234 0.0312
Loa Loa (eye worm) TK/ALK protein kinase 0.0286 0.2281 0.2281
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0084 0.0234 0.0312
Giardia lamblia Kinase, CMGC CDK 0.0124 0.0642 0.0671
Entamoeba histolytica protein kinase, putative 0.0127 0.0677 0.0593
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0208 0.1493 0.1533
Schistosoma mansoni vam6/vps39 related 0.0112 0.0522 0.0774
Brugia malayi phosphoinositide-dependent protein kinase I 0.0087 0.0264 0.02
Entamoeba histolytica casein kinase, putative 0.0105 0.0453 0.0366
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0286 0.0199
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0236 0.1772 0.2203
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0099 0.0393 0.0567
Echinococcus granulosus calcium activated potassium channel 0.014 0.0805 0.0827
Onchocerca volvulus 0.0331 0.2736 0.5405
Schistosoma mansoni protein kinase 0.0243 0.1843 0.2898
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0144 0.0847 0.304
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0198 0.1393 0.1393
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0453 0.0366
Schistosoma mansoni nephrin 0.0121 0.0613 0.0921
Loa Loa (eye worm) hypothetical protein 0.0106 0.046 0.046
Schistosoma mansoni protein kinase 0.0158 0.0991 0.1528
Brugia malayi cell division control protein 2 homolog 0.0124 0.0642 0.0581
Brugia malayi Protein kinase domain containing protein 0.0087 0.0264 0.02
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0089 0.0286 0.0286
Echinococcus granulosus protein kinase c iota type 0.0533 0.4778 0.4906
Giardia lamblia Kinase, CMGC DYRK 0.0144 0.0847 0.1051
Brugia malayi Protein kinase domain containing protein 0.0206 0.1474 0.1418
Schistosoma mansoni serine/threonine protein kinase 0.0408 0.3512 0.5583
Plasmodium falciparum calcium-dependent protein kinase 5 0.0106 0.046 0.0372
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0088 0.028 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.0642 0.0968
Loa Loa (eye worm) hypothetical protein 0.0099 0.0393 0.0393
Trichomonas vaginalis CAMK family protein kinase 0.0276 0.2179 0.2109
Entamoeba histolytica protein kinase, putative 0.1049 1 1
Echinococcus granulosus cyclin dependent kinase 1 0.0124 0.0642 0.066
Brugia malayi Fes/CIP4 homology domain containing protein 0.0117 0.0575 0.0513
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0463 0.0463
Echinococcus granulosus twitchin 0.0143 0.0838 0.086
Leishmania major protein kinase, putative 0.009 0.0296 0.016
Schistosoma mansoni protein kinase 0.0151 0.0913 0.1403
Schistosoma mansoni serine/threonine protein kinase 0.0491 0.4352 0.6933
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0384 0.0552
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0118 0.0584 0.0701
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Schistosoma mansoni serine/threonine protein kinase 0.0221 0.1629 0.2554
Onchocerca volvulus 0.0143 0.0837 0.1602
Onchocerca volvulus 0.0106 0.0463 0.0852
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0468 0.4124 0.5126
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Echinococcus multilocularis serine threonine protein kinase 0.0449 0.3927 0.4882
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0118 0.0584 0.0327
Brugia malayi Immunoglobulin I-set domain containing protein 0.0269 0.2113 0.2062
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0584 0.0874
Echinococcus multilocularis serine:threonine protein kinase 3 0.0262 0.2043 0.2539
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0095 0.0352 0.0265
Onchocerca volvulus 0.0095 0.0348 0.0621
Echinococcus multilocularis tyrosine protein kinase shark 0.032 0.2629 0.3268
Entamoeba histolytica protein kinase, putative 0.0408 0.3512 0.3454
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0805 0.123
Echinococcus granulosus casein kinase I gamma 0.0219 0.16 0.1643
Plasmodium falciparum protein kinase 5 0.0124 0.0642 0.0708
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0492 0.4366 0.5427
Echinococcus granulosus dual specificity 0.0144 0.0847 0.087
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0102 0.042 0.0431
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0122 0.0625 0.0564
Trichomonas vaginalis AGC family protein kinase 0.1049 1 1
Echinococcus multilocularis serine:threonine protein kinase 0.0119 0.0595 0.0739
Plasmodium vivax serine/threonine kinase-1, putative 0.0098 0.0384 0.0619
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0453 0.0366
Brugia malayi Variant SH3 domain containing protein 0.0099 0.0393 0.0331
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Echinococcus granulosus ephrin type A receptor 4 A 0.0113 0.0531 0.0545
Loa Loa (eye worm) hypothetical protein 0.0209 0.15 0.15
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0221 0.1629 0.1672
Brugia malayi serine/threonine-protein kinase plk-2 0.0276 0.2179 0.2128
Echinococcus granulosus casein kinase I delta 0.0114 0.0539 0.0554
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0276 0.2179 0.2709
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0087 0.0265 0.0007
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0463 0.0463
Entamoeba histolytica protein kinase, putative 0.0091 0.031 0.0222
Echinococcus granulosus cGMP dependent protein kinase 1 0.014 0.0803 0.0824
Schistosoma mansoni tyrosine kinase 0.0376 0.319 0.5064
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.095 0.8995 0.8995
Echinococcus granulosus tyrosine protein kinase Lyn 0.0274 0.2156 0.2214
Trichomonas vaginalis STE family protein kinase 0.0141 0.0818 0.0735
Entamoeba histolytica protein kinase, putative 0.0096 0.0355 0.0268
Echinococcus multilocularis casein kinase I delta 0.0114 0.0539 0.067
Leishmania major protein kinase, putative 0.0098 0.0384 0.0619
Entamoeba histolytica protein kinase domain containing protein 0.0127 0.0677 0.0593
Echinococcus multilocularis dual specificity 0.0144 0.0847 0.1053
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Echinococcus multilocularis PAK box P21 Rho binding 0.0069 0.009 0.0111
Schistosoma mansoni protein kinase 0.044 0.384 0.611
Schistosoma mansoni serine/threonine protein kinase 0.0358 0.3014 0.4782
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0071 0.0102 0.0105
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0144 0.0847 0.0598
Loa Loa (eye worm) TK/EGFR protein kinase 0.0616 0.5615 0.5615
Schistosoma mansoni protein kinase 0.0114 0.0539 0.0802
Echinococcus granulosus rho-associated protein kinase 1 0.0331 0.2736 0.2809
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0087 0.0264 0.0264
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0463 0.0463
Echinococcus multilocularis mitogen activated protein kinase 11 0.0164 0.1051 0.1307
Onchocerca volvulus 0.0106 0.0463 0.0852
Schistosoma mansoni protein kinase 0.0198 0.1393 0.2175
Leishmania major folate/biopterin transporter, putative 0.0096 0.0355 0.0471
Brugia malayi casein kinase 1, delta 0.0114 0.0539 0.0478
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0144 0.0847 0.1132
Echinococcus granulosus tyrosine protein kinase Fyn 0.0236 0.1772 0.182
Echinococcus granulosus casein kinase I delta 0.0114 0.0539 0.0554
Entamoeba histolytica protein kinase, putative 0.0096 0.0355 0.0268
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0241 0.1821 0.2264
Plasmodium falciparum protein serine/threonine kinase-1 0.0098 0.0384 0.023
Brugia malayi Protein kinase domain containing protein 0.0106 0.0463 0.0401
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.012 0.0605 0.0752
Brugia malayi hypothetical protein 0.0228 0.1692 0.1637
Echinococcus multilocularis NCK adaptor protein 0.0101 0.0406 0.0505
Entamoeba histolytica protein kinase domain containing protein 0.0134 0.0742 0.0659
Schistosoma mansoni protein kinase 0.0243 0.1843 0.2898
Schistosoma mansoni tyrosine kinase 0.0616 0.5615 0.8964
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0127 0.0677 0.0854
Brugia malayi Protein kinase domain containing protein 0.0119 0.0595 0.0534
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0355 0.0268
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0411 0.3541 0.4402
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0169 0.1102 0.1131
Echinococcus granulosus mitogen activated protein kinase 3 0.0089 0.0286 0.0294
Schistosoma mansoni hypothetical protein 0.0102 0.0422 0.0613
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.1474 0.2305
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0091 0.031 0.0385
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0164 0.1051 0.0808
Trypanosoma cruzi cdc2-related kinase 1 0.0124 0.0642 0.0797
Echinococcus multilocularis protein kinase c iota type 0.0533 0.4778 0.5939
Echinococcus multilocularis calcium dependent protein kinase 0.0068 0.0077 0.0095
Plasmodium falciparum calcium-dependent protein kinase 7 0.0096 0.0355 0.0178
Schistosoma mansoni ephrin receptor 0.0113 0.0531 0.0789
Schistosoma mansoni serine/threonine protein kinase 0.027 0.2118 0.3341
Leishmania major protein kinase A catalytic subunit 0.0118 0.0584 0.1664
Giardia lamblia Kinase, STE STE20 0.009 0.0296 0.0029
Echinococcus multilocularis cyclin dependent kinase 0.0124 0.0642 0.0798
Trypanosoma brucei Casein kinase II 0.0105 0.0453 0.0193
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0286 0.0199
Loa Loa (eye worm) TK/FER protein kinase 0.0411 0.3541 0.3541
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0064 0.0033 0.0034
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.009 0.0296 0.0229
Loa Loa (eye worm) TK protein kinase 0.0137 0.0774 0.0774
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0164 0.1051 0.1467
Plasmodium falciparum calcium-dependent protein kinase 1 0.0106 0.046 0.0372
Plasmodium falciparum calcium-dependent protein kinase 3 0.0106 0.046 0.0372
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.015 0.0905 0.0929
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0118 0.0584 0.0726
Loa Loa (eye worm) hypothetical protein 0.0099 0.0386 0.0386
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.027 0.2118 0.2118
Brugia malayi Protein kinase domain containing protein 0.0286 0.2282 0.2232
Echinococcus multilocularis cyclin dependent kinase 1 0.0124 0.0642 0.0798
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0124 0.0642 0.066
Trypanosoma cruzi casein kinase, putative 0.0114 0.0539 0.0628
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0096 0.0355 0.0327
Toxoplasma gondii histone kinase SNF1, putative 0.0095 0.0344 0.0093
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0119 0.0595 0.0595
Schistosoma mansoni protein kinase 0.0271 0.2125 0.3351
Echinococcus granulosus Glutaredoxin protein 5 0.0584 0.5291 0.5433
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.16 0.2509
Echinococcus multilocularis tyrosine protein kinase Abl 0.0227 0.1684 0.2094
Leishmania major casein kinase, putative 0.0114 0.0539 0.1433
Trypanosoma brucei casein kinase I, isoform 2 0.0114 0.0539 0.0282
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.015 0.0086
Brugia malayi Protein kinase domain containing protein 0.0222 0.1638 0.1584
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0088 0.028 0.0204
Entamoeba histolytica protein kinase domain containing protein 0.0151 0.0913 0.0831
Echinococcus granulosus Pleckstrin y 0.0064 0.0033 0.0034
Echinococcus granulosus tyrosine protein kinase HCK 0.0137 0.0774 0.0795
Entamoeba histolytica protein kinase, putative 0.0991 0.9416 0.9411
Echinococcus multilocularis epidermal growth factor receptor 0.0407 0.3503 0.4354
Trypanosoma cruzi casein kinase, putative 0.0114 0.0539 0.0628
Toxoplasma gondii casein kinase I 0.0114 0.0539 0.0306
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0221 0.1629 0.1672
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0181 0.1221 0.1221
Echinococcus granulosus dual specificity 0.0127 0.0677 0.0695
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0033
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0112 0.0522 0.0599
Trichomonas vaginalis AGC family protein kinase 0.0151 0.0913 0.0831
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0492 0.4366 0.4366
Loa Loa (eye worm) hypothetical protein 0.0362 0.3047 0.3047
Echinococcus multilocularis mitogen activated protein kinase 0.0089 0.0286 0.0356
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0095 0.0344 0.0548
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.0847 0.0764
Schistosoma mansoni tyrosine kinase 0.0263 0.2048 0.3228
Schistosoma mansoni growth factor receptor-bound protein 0.0101 0.0406 0.0588
Brugia malayi Protein kinase domain containing protein 0.0455 0.3988 0.3949
Echinococcus granulosus tyrosine kinase 0.0194 0.1355 0.1392
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0241 0.1821 0.187
Trichomonas vaginalis AGC family protein kinase 0.0486 0.4304 0.4252
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0105 0.0453 0.0741
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0236 0.1772 0.2203
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0096 0.0355 0.0471
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Brugia malayi Serine/threonine-protein kinase SULU 0.0228 0.1692 0.1637
Brugia malayi Hr1 repeat family protein 0.0538 0.4828 0.4794
Echinococcus granulosus N chimaerin 0.0099 0.0393 0.0404
Brugia malayi Protein kinase domain containing protein 0.0607 0.5525 0.5496
Trypanosoma cruzi cdc2-related kinase 1 0.0124 0.0642 0.0797
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0118 0.0584 0.0973
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0236 0.1772 0.2203
Brugia malayi serine/threonine-protein kinase 6 0.0151 0.0913 0.0854
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0075 0.015 0.015
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.018 0.1209 0.493
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0191 0.1322 0.1643
Entamoeba histolytica protein kinase, putative 0.0088 0.028 0.0192
Brugia malayi Protein kinase domain containing protein 0.0106 0.0463 0.0401
Trichomonas vaginalis AGC family protein kinase 0.0408 0.3512 0.3454
Echinococcus multilocularis protein tyrosine kinase 0.0556 0.5017 0.6236
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0096 0.0355 0.0327
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.0847 0.0764
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.2024 0.319
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0118 0.0584 0.0726
Trichomonas vaginalis CAMK family protein kinase 0.0132 0.0719 0.0635
Echinococcus multilocularis rho associated protein kinase 0.0331 0.2736 0.3401
Echinococcus granulosus tyrosine protein kinase shark 0.032 0.2629 0.27
Echinococcus granulosus serine:threonine protein kinase N2 0.013 0.0703 0.0722
Echinococcus multilocularis myosin iiia 0.009 0.0296 0.0368
Onchocerca volvulus 0.0293 0.2352 0.4636
Loa Loa (eye worm) protein kinase domain-containing protein 0.0219 0.16 0.16
Loa Loa (eye worm) TK/ROR protein kinase 0.0071 0.0102 0.0102
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0463 0.0463
Toxoplasma gondii AGC kinase 0.0991 0.9416 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0276 0.2179 0.3315
Entamoeba histolytica serine/threonine protein kinase, putative 0.0276 0.2179 0.2109
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0099 0.0386 0.0555
Trichomonas vaginalis AGC family protein kinase 0.1049 1 1
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0501 0.4453 0.4573
Echinococcus granulosus nervana 2 0.0584 0.5291 0.5433
Schistosoma mansoni tyrosine kinase 0.0358 0.3009 0.4773
Trichomonas vaginalis CMGC family protein kinase 0.0134 0.0742 0.0659
Schistosoma mansoni serine/threonine protein kinase 0.0492 0.4366 0.6955
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0358 0.3014 0.3014
Loa Loa (eye worm) hypothetical protein 0.0106 0.0463 0.0463
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0091 0.031 0.0318
Entamoeba histolytica hypothetical protein 0.0099 0.0389 0.0302
Loa Loa (eye worm) AGC/AKT protein kinase 0.1049 1 1
Echinococcus granulosus cGMP dependent protein kinase 0.014 0.0803 0.0824
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0098 0.0384 0.0373
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0358 0.3014 0.3014
Brugia malayi protein kinase C II. 0.0451 0.3949 0.391
Onchocerca volvulus 0.0095 0.0348 0.0621
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0141 0.0818 0.1389
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0344 0.0488
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0089 0.0286 0.0022
Leishmania major protein kinase, putative 0.0096 0.0355 0.0471
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0164 0.1051 0.1467
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0114 0.0539 0.0628
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.044 0.384 0.4773
Brugia malayi Protein kinase domain containing protein 0.0408 0.3512 0.347
Entamoeba histolytica protein kinase domain containing protein 0.0208 0.1493 0.1416
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0539 0.0802
Trypanosoma brucei rac serine-threonine kinase, putative 0.1049 1 1
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0276 0.2179 0.2179
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0617 0.0927
Schistosoma mansoni tyrosine kinase 0.0236 0.1772 0.2785
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0144 0.0847 0.0787
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0118 0.0584 0.0522
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0191 0.1322 0.1322
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0089 0.0286 0.0214
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0453 0.0366
Echinococcus granulosus tyrosine protein kinase Src42A 0.0236 0.1772 0.182
Echinococcus multilocularis Immunoglobulin 0.0084 0.0234 0.0291
Echinococcus multilocularis tyrosine protein kinase Srms 0.0194 0.1355 0.1685
Plasmodium falciparum calcium-dependent protein kinase 2 0.0106 0.046 0.0372
Schistosoma mansoni serine/threonine protein kinase 0.04 0.3437 0.5461
Echinococcus granulosus tyrosine kinase 0.0106 0.0463 0.0475
Schistosoma mansoni serine/threonine protein kinase 0.0208 0.1493 0.2336
Echinococcus multilocularis casein kinase I delta 0.0114 0.0539 0.067
Echinococcus multilocularis cyclin dependent kinase 5 0.0124 0.0642 0.0798
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0079 0.0186 0.0186
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0134 0.0742 0.0961
Echinococcus granulosus serine threonine protein kinase nrc 0.0621 0.5675 0.5827
Brugia malayi Protein kinase domain containing protein 0.0289 0.2314 0.2264
Echinococcus multilocularis rac serine:threonine kinase 0.0679 0.6259 0.778
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0134 0.0742 0.0742
Entamoeba histolytica protein kinase, putative 0.0134 0.0742 0.0659
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0114 0.0539 0.0539
Schistosoma mansoni tyrosine kinase 0.0407 0.3503 0.5567
Echinococcus granulosus tyrosine protein kinase Srms 0.0515 0.46 0.4723
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.015 0.0906 0.0931
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0803 0.1225
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0264 0.0176
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0088 0.028 0.028
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0236 0.1772 0.2203
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0223 0.1645 0.1591
Brugia malayi Protein kinase domain containing protein 0.0358 0.3014 0.2969
Echinococcus multilocularis c Jun NH2 terminal kinase 0.027 0.2118 0.2633
Trichomonas vaginalis AGC family protein kinase 0.0151 0.0913 0.0831
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0127 0.0677 0.0854
Echinococcus granulosus serine/threonine protein kinase 0.0679 0.6259 0.6427
Brugia malayi Furin-like cysteine rich region family protein 0.0616 0.5615 0.5586
Loa Loa (eye worm) casein kinase 0.0181 0.1217 0.1217
Onchocerca volvulus 0.0114 0.0539 0.1005
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0355 0.0268
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0208 0.1493 0.1437
Loa Loa (eye worm) AGC/PKG protein kinase 0.014 0.0803 0.0803
Brugia malayi p70 ribosomal S6 kinase beta 0.0991 0.9416 0.9412
Echinococcus multilocularis casein kinase i 0.0114 0.0539 0.067
Schistosoma mansoni protein kinase 0.0087 0.0265 0.0361
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0071 0.0102 0.0127
Giardia lamblia Kinase, CMGC CK2 0.0105 0.0453 0.032
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.008 0.02 0.0249
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.04 0.3437 0.4272
Trichomonas vaginalis CAMK family protein kinase 0.012 0.0605 0.052
Onchocerca volvulus 0.0112 0.0522 0.097
Entamoeba histolytica hypothetical protein 0.0096 0.0355 0.0268
Loa Loa (eye worm) SRC-1 0.0236 0.1772 0.1772
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0118 0.0584 0.0726
Leishmania major protein kinase, putative 0.0151 0.0913 0.3385
Echinococcus granulosus myotubularin protein 13 0.01 0.0396 0.0407
Plasmodium falciparum serine/threonine protein kinase, putative 0.0151 0.0913 0.1208
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0118 0.0584 0.06
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0099 0.0393 0.0393
Brugia malayi casein kinase I 0.0114 0.0539 0.0478
Onchocerca volvulus 0.0185 0.1261 0.2452
Giardia lamblia Kinase, CMGC CDK 0.0124 0.0642 0.0671
Entamoeba histolytica protein kinase domain containing protein 0.0134 0.0742 0.0659
Echinococcus multilocularis growth factor receptor bound protein 2 0.0099 0.0386 0.048
Giardia lamblia Kinase, CMGC MAPK 0.0089 0.0286 0.0012
Loa Loa (eye worm) hypothetical protein 0.0143 0.0837 0.0837
Brugia malayi Protein kinase domain containing protein 0.0562 0.5078 0.5046
Echinococcus multilocularis dual specificity 0.0144 0.0847 0.1053
Trichomonas vaginalis CMGC family protein kinase 0.0095 0.0348 0.026
Loa Loa (eye worm) hypothetical protein 0.0112 0.0522 0.0522
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0095 0.0344 0.0308
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0228 0.1692 0.2103
Echinococcus multilocularis casein kinase I alpha 0.0114 0.0539 0.067
Trichomonas vaginalis STE family protein kinase 0.009 0.0296 0.0208
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0264 0.0176
Entamoeba histolytica protein kinase, putative 0.0087 0.0264 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.0451 0.3949 0.6286
Brugia malayi serine/threonine kinase 12 0.0151 0.0913 0.0854
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0236 0.1772 0.182
Echinococcus multilocularis Pleckstrin y 0.0064 0.0033 0.0041
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0243 0.1843 0.1892
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0453 0.0366
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0099 0.0389 0.056
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.039 0.3336 0.3276
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0164 0.1051 0.1051
Schistosoma mansoni tyrosine kinase 0.0452 0.3965 0.6311
Echinococcus multilocularis 0.0174 0.115 0.1429
Loa Loa (eye worm) hypothetical protein 0.0362 0.3047 0.3047
Trypanosoma brucei cdc2-related kinase 3 0.0124 0.0642 0.0387
Brugia malayi Pleckstrin Homology Domain 0.01 0.0396 0.0334
Onchocerca volvulus Tyrosine kinase homolog 0.0558 0.503 1
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0286 0.0199
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0344 0.0488
Loa Loa (eye worm) AGC/NDR protein kinase 0.0408 0.3512 0.3512
Echinococcus granulosus CDC7 cell division cycle 7 0.0095 0.0348 0.0357
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0358 0.3014 0.3095
Trichomonas vaginalis CAMK family protein kinase 0.0276 0.2179 0.2109
Entamoeba histolytica protein kinase, putative 0.0127 0.0674 0.0589
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.046 0.0374
Brugia malayi Protein kinase domain containing protein 0.0106 0.0463 0.0401
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0208 0.1493 0.1856
Trypanosoma cruzi casein kinase II, putative 0.0105 0.0453 0.0486
Schistosoma mansoni serine/threonine protein kinase 0.0221 0.1629 0.2554
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0118 0.0584 0.0355
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.012 0.0605 0.0621
Schistosoma mansoni vav2 0.0157 0.0977 0.1506
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0584 0.5291 0.6577
Echinococcus granulosus serine:threonine protein kinase 0.0119 0.0595 0.0611
Schistosoma mansoni vesicular amine transporter 0.0084 0.0234 0.0312
Schistosoma mansoni protein kinase 0.044 0.384 0.611
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0276 0.2179 0.2238
Trypanosoma cruzi casein kinase, putative 0.0114 0.0539 0.0628
Schistosoma mansoni serine/threonine protein kinase 0.0276 0.2179 0.3439
Schistosoma mansoni protein kinase 0.0091 0.031 0.0433
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0098 0.0384 0.0384
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0621 0.5675 1
Schistosoma mansoni serine/threonine protein kinase 0.0331 0.2736 0.4334
Echinococcus multilocularis tyrosine protein kinase HCK 0.0137 0.0774 0.0962
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0228 0.1692 0.1692
Loa Loa (eye worm) hypothetical protein 0.0124 0.064 0.064
Echinococcus multilocularis dual specificity protein kinase clk2 0.0098 0.0384 0.0477
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0191 0.1322 0.1357
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0106 0.046 0.022
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0106 0.046 0.0472
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Schistosoma mansoni tyrosine kinase 0.0358 0.3009 0.4773
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0076 0.0156 0.016
Schistosoma mansoni cell adhesion molecule 0.0118 0.0579 0.0866
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0584 0.0874
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0099 0.0393 0.0489
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0408 0.3512 0.3606
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0096 0.0355 0.0093
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0586 0.5313 0.5313
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0428 0.372 0.372
Onchocerca volvulus Serine\/threonine kinase homolog 0.0169 0.1102 0.2132
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0096 0.0355 0.0105
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.028 0.0385
Loa Loa (eye worm) TK protein kinase 0.0194 0.1355 0.1355
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0451 0.3949 0.3949
Echinococcus granulosus titin 0.0075 0.015 0.0154
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0106 0.046 0.0472
Echinococcus granulosus epidermal growth factor receptor 0.0407 0.3503 0.3596
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.1322 0.2061
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.1821 0.2864
Trichomonas vaginalis AGC family protein kinase 0.0151 0.0913 0.0831
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0156 0.0967 0.0967
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0095 0.0344 0.0412
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0114 0.0539 0.0539
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0584 0.5291 0.5433
Trypanosoma brucei aurora B kinase 0.0151 0.0913 0.0666
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0463 0.0463
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0344 0.0488
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0355 0.0268
Toxoplasma gondii AGC kinase 0.0118 0.0584 0.0355
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0106 0.046 0.022
Plasmodium vivax protein kinase Crk2 0.0124 0.0642 0.1077
Echinococcus granulosus protein kinase 0.0158 0.0991 0.1017
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0112 0.0522 0.0536
Schistosoma mansoni tyrosine kinase 0.0556 0.5017 0.8003
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.0847 0.0764
Brugia malayi Protein kinase domain containing protein 0.0106 0.0463 0.0401
Trichomonas vaginalis AGC family protein kinase 0.1049 1 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0236 0.1772 0.182
Onchocerca volvulus 0.0106 0.0463 0.0852
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0169 0.1099 0.1099
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0087 0.0264 0.0328
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0134 0.0742 0.0762
Onchocerca volvulus 0.0134 0.0742 0.1412
Trichomonas vaginalis CMGC family protein kinase 0.0134 0.0742 0.0659
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0679 0.6259 1
Trichomonas vaginalis CMGC family protein kinase 0.0124 0.0642 0.0558
Echinococcus multilocularis aurora kinase A 0.0151 0.0913 0.1135
Leishmania major protein kinase A catalytic subunit isoform 2 0.0118 0.0584 0.1664
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0334 0.2767 0.2767
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0124 0.0642 0.1971
Brugia malayi Protein kinase domain containing protein 0.0373 0.3158 0.3114
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0095 0.0344 0.0412
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0114 0.0539 0.0539
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0099 0.0393 0.0404
Schistosoma mansoni hypothetical protein 0.0112 0.0522 0.0774
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0358 0.3014 0.5962
Echinococcus granulosus protein kinase shaggy 0.0134 0.0742 0.0762
Echinococcus granulosus dual specificity protein kinase clk2 0.0098 0.0384 0.0394
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0236 0.1772 0.2203
Schistosoma mansoni tyrosine kinase 0.032 0.2629 0.4163
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0134 0.0742 0.0528
Loa Loa (eye worm) TK/FER protein kinase 0.0106 0.0463 0.0463
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0106 0.046 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Entamoeba histolytica casein kinase 1, putative 0.0114 0.0539 0.0454
Echinococcus granulosus protein kinase C gamma type 0.0449 0.3927 0.4033
Brugia malayi Protein kinase domain containing protein 0.0169 0.1102 0.1044
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0453 0.0366
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0236 0.1772 0.2203
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0134 0.0742 0.0923
Entamoeba histolytica protein kinase , putative 0.0151 0.0913 0.0831
Entamoeba histolytica protein kinase 2, putative 0.0621 0.5675 0.5636
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Echinococcus multilocularis dual specificity 0.0127 0.0677 0.0842
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0118 0.0584 0.0726
Brugia malayi ephrin receptor 1 precursor 0.0079 0.0188 0.0124
Trypanosoma cruzi casein kinase, putative 0.0114 0.0539 0.0628
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0621 0.5675 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.015 0.0905 0.1125
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0221 0.1629 0.2024
Entamoeba histolytica protein kinase, putative 0.0106 0.046 0.0374
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0091 0.031 0.0385
Leishmania major protein kinase, putative 0.0106 0.046 0.1018
Entamoeba histolytica protein kinase, putative 0.0137 0.0774 0.0691
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.1638 0.1563
Echinococcus granulosus casein kinase ii subunit alpha 0.0105 0.0453 0.0465
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0094 0.0336 0.0336
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0638 0.5842 0.5842
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0264 0.0359
Echinococcus granulosus mitogen activated protein kinase 14 0.0164 0.1051 0.108
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0118 0.0584 0.0701
Echinococcus multilocularis casein kinase I alpha 0.0114 0.0539 0.067
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0408 0.3512 0.4366
Echinococcus granulosus NDR protein kinase 0.0408 0.3512 0.3606
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0621 0.5675 0.5827
Loa Loa (eye worm) hypothetical protein 0.024 0.1821 0.1821
Brugia malayi Protein kinase domain containing protein 0.0428 0.372 0.3679
Schistosoma mansoni serine/threonine kinase 0.0222 0.1638 0.257
Loa Loa (eye worm) hypothetical protein 0.0139 0.0796 0.0796
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0805 0.123
Echinococcus granulosus aurora kinase A 0.0151 0.0913 0.0938
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0314 0.2567 0.3191
Loa Loa (eye worm) AGC/PKN protein kinase 0.0538 0.4828 0.4828
Echinococcus multilocularis serine:threonine protein kinase N2 0.0408 0.3512 0.4366
Loa Loa (eye worm) hypothetical protein 0.0095 0.0344 0.0344
Giardia lamblia Kinase, AGC PKA 0.0118 0.0584 0.0563
Brugia malayi Protein kinase domain containing protein 0.0193 0.1338 0.1282
Echinococcus granulosus tyrosine protein kinase Src42A 0.0148 0.0882 0.0905
Brugia malayi protein unc-22 0.0075 0.015 0.0086
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0248 0.1893 0.1944
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0089 0.0286 0.0214
Schistosoma mansoni protein kinase 0.0105 0.0453 0.0663
Echinococcus multilocularis dual specificity 0.0144 0.0847 0.1053
Brugia malayi Kinase associated domain 1 family protein 0.0102 0.0422 0.0359
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0344 0.0257
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0248 0.1893 0.2353
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0106 0.046 0.046
Schistosoma mansoni tyrosine kinase 0.0147 0.088 0.135
Trichomonas vaginalis CAMK family protein kinase 0.0276 0.2179 0.2109
Loa Loa (eye worm) hypothetical protein 0.0118 0.0584 0.0584
Loa Loa (eye worm) hypothetical protein 0.0233 0.1741 0.1741
Entamoeba histolytica protein kinase, putative 0.0076 0.0156 0.0067
Plasmodium falciparum casein kinase 2, alpha subunit 0.0105 0.0453 0.0358
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0563 0.0477
Echinococcus multilocularis roundabout 2 0.014 0.0799 0.0993
Trichomonas vaginalis STE family protein kinase 0.0091 0.031 0.0222
Giardia lamblia Kinase, NEK 0.0141 0.0818 0.0998
Schistosoma mansoni protein kinase 0.0069 0.009 0.0079
Brugia malayi Fibronectin type III domain containing protein 0.0099 0.0393 0.0331
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0221 0.1629 0.2024
Plasmodium vivax calcium-dependent protein kinase, putative 0.0106 0.046 0.0754
Echinococcus multilocularis tyrosine kinase 0.0106 0.0463 0.0575
Echinococcus multilocularis serine:threonine protein kinase 38 0.0408 0.3512 0.4366
Trichomonas vaginalis CAMK family protein kinase 0.0119 0.0595 0.051
Entamoeba histolytica p21-activated kinase 0.0149 0.0894 0.0811
Trypanosoma cruzi Protein kinase B 0.0679 0.6259 1
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0088 0.028 0.0015
Brugia malayi hypothetical protein 0.0112 0.0522 0.046
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0116 0.0566 0.0566
Brugia malayi Immunoglobulin I-set domain containing protein 0.0099 0.0393 0.0331
Echinococcus multilocularis death associated protein kinase 1 0.0856 0.8045 1
Trichomonas vaginalis CAMK family protein kinase 0.0132 0.0719 0.0635
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0096 0.0355 0.0327
Echinococcus multilocularis cGMP dependent protein kinase 1 0.014 0.0803 0.0998
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.009 0.0296 0.0208
Entamoeba histolytica protein kinase, putative 0.0127 0.0677 0.0593
Echinococcus granulosus tyrosine protein kinase Blk 0.0194 0.1355 0.1392
Echinococcus multilocularis cGMP dependent protein kinase 1 0.014 0.0803 0.0998
Brugia malayi Cam kinase protein 1 0.0106 0.046 0.0398
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0096 0.0355 0.0568
Schistosoma mansoni atypical protein kinase C 0.0539 0.484 0.7717
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0106 0.046 0.0572
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0384 0.0552
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0805 0.123
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0206 0.1474 0.1832
Trypanosoma cruzi cdc2-related kinase 3 0.0124 0.0642 0.0797

Activities

Activity type Activity value Assay description Source Reference
IC50 (ADMET) < 1 ug ml-1 Cytotoxicity against human HT29 cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) < 1 ug ml-1 Cytotoxicity against human L132 cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) < 1 ug ml-1 Cytotoxicity against human Hep2 cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) < 1 ug ml-1 Cytotoxicity against human HT29 cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) < 1 ug ml-1 Cytotoxicity against human L132 cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) = 16 ug ml-1 Cytotoxicity against human DU145 cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) = 16 ug ml-1 Cytotoxicity against human DU145 cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) = 33 ug ml-1 Cytotoxicity against human KB cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) = 33 ug ml-1 Cytotoxicity against human KB cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) = 39.5 ug ml-1 Cytotoxicity against human MiaPaCa2 cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) = 39.5 ug ml-1 Cytotoxicity against human MiaPaCa2 cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) = 41 ug ml-1 Cytotoxicity against human ECV304 cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) = 59 ug ml-1 Cytotoxicity against human HEK293 cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) = 59 ug ml-1 Cytotoxicity against human HEK293 cells after 72 hrs by MTT assay ChEMBL. 17373779
IC50 (ADMET) > 100 ug ml-1 Cytotoxicity against human PA1 cells after 72 hrs by MTT assay ChEMBL. 17373779

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 17373779

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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