Detailed information for compound 41797

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 520.617 | Formula: C30H36N2O6
  • H donors: 2 H acceptors: 4 LogP: 3.69 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCOC(=O)N[C@H]([C@H](C(=O)OC1CC2C(C1(C)[C@]13[C@@]2(O3)c2ccccc2[C@H](C1)C)(C)C)O)c1cccnc1
  • InChi: 1S/C30H36N2O6/c1-6-36-26(35)32-23(18-10-9-13-31-16-18)24(33)25(34)37-22-14-21-27(3,4)28(22,5)29-15-17(2)19-11-7-8-12-20(19)30(21,29)38-29/h7-13,16-17,21-24,33H,6,14-15H2,1-5H3,(H,32,35)/t17-,21?,22?,23-,24+,28?,29-,30+/m0/s1
  • InChiKey: DXVPDABBUQPVFR-KOZGNGJDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Schistosoma mansoni metabotropic glutamate receptor 0.303 0.6923 0.782
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0006 0.0007
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0039 0.162
Echinococcus granulosus excitatory amino acid transporter 2 0.1364 0.3094 0.3094
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0219 0.0219
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0499 0.1107 0.3563
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0006 0.0006
Schistosoma mansoni glutamate receptor NMDA 0.1216 0.2755 0.3112
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0006 0.0007
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.009 0.009
Echinococcus granulosus glutamate receptor 2 0.0917 0.2066 0.2065
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0067 0.0075
Loa Loa (eye worm) hypothetical protein 0.0056 0.0088 0.0088
Chlamydia trachomatis neutral amino acid transporter 0.0605 0.1349 0.4305
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0241 0.0271
Brugia malayi regulator of G-protein signaling egl-10 0.0059 0.0094 0.0115
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0006 0.0006
Echinococcus multilocularis Excitatory amino acid transporter 0.1364 0.3094 0.3094
Echinococcus multilocularis glutamate receptor 2 0.1266 0.2869 0.2869
Echinococcus multilocularis neutral amino acid transporter A 0.1364 0.3094 0.3094
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0094 0.0764
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0039 0.0263
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0045 0.2036
Loa Loa (eye worm) hypothetical protein 0.0552 0.1229 0.1229
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0006 0.0006
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0006 0.0006
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0006 0.0006
Echinococcus multilocularis lamin dm0 0.0057 0.009 0.009
Loa Loa (eye worm) cytochrome P450 family protein 0.0075 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0499 0.1107 0.1107
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0117 0.0117
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0241 0.0271
Echinococcus multilocularis RUN 0.0021 0.0006 0.0006
Echinococcus granulosus metabotropic glutamate receptor 2 0.303 0.6923 0.6923
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0096 0.018 0.0203
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0117 0.0117
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0059 0.0094 0.0094
Onchocerca volvulus 0.0108 0.0208 0.0654
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0029 0.0035
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.174 0.3959 0.3959
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0439 0.0968 0.0968
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0006 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0219 0.1903
Schistosoma mansoni tyrosine kinase 0.0499 0.1107 0.125
Brugia malayi hypothetical protein 0.0021 0.0006 0.0008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0006 0.0006
Loa Loa (eye worm) norepinephrine transporter 0.0059 0.0094 0.0094
Echinococcus multilocularis metabotropic glutamate receptor 2 0.303 0.6923 0.6923
Toxoplasma gondii exonuclease III APE 0.0058 0.0093 0.3855
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.001 0.0449
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0284 0.0612 0.0611
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0067 0.0514
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.003 0.2859
Schistosoma mansoni lamin 0.0057 0.009 0.0101
Echinococcus multilocularis glutamate receptor 4 0.005 0.0073 0.0073
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0006 0.0007
Schistosoma mansoni glutamate receptor AMPA 0.0717 0.1608 0.1816
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0093 1
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0006 0.0007
Brugia malayi 6-phosphofructokinase 0.0113 0.0219 0.0267
Schistosoma mansoni regulator of G protein signaling 0.0059 0.0094 0.0106
Brugia malayi hypothetical protein 0.0059 0.0094 0.0115
Echinococcus granulosus voltage dependent calcium channel subunit 0.0129 0.0256 0.0256
Echinococcus granulosus neutral amino acid transporter A 0.1364 0.3094 0.3094
Brugia malayi Cache domain containing protein 0.0057 0.0091 0.011
Brugia malayi Metabotropic glutamate receptor precursor. 0.3582 0.8193 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0006 0.0007
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0605 0.1349 0.1523
Onchocerca volvulus Excitatory amino acid transporter homolog 0.1364 0.3094 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.174 0.3959 0.3959
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0006 0.0007
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0006 0.0007
Echinococcus multilocularis musashi 0.0057 0.009 0.009
Echinococcus granulosus glutamate receptor 1 0.005 0.0073 0.0073
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0091 0.0091
Brugia malayi nuclear hormone receptor 0.002 0.0006 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0006 0.0007
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0006 0.0006
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.1364 0.3094 1
Onchocerca volvulus 0.0499 0.1107 0.3563
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0006 0.0006
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0067 0.0066
Schistosoma mansoni intermediate filament proteins 0.0057 0.009 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0017 0.0064
Onchocerca volvulus 0.05 0.1108 0.3567
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0093 0.0837
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0006 0.0007
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.174 0.3959 0.3959
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0117 0.1056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0104 0.0117
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0067 0.3036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0039 0.0263
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0059 0.0094 0.0115
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0006 0.0006
Trichomonas vaginalis set domain proteins, putative 0.05 0.1108 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0006 0.0006
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0006 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0006 0.0006
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0117 0.1056
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.174 0.3959 0.3959
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0117 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0017 0.0063
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0094 0.0106
Brugia malayi Excitatory amino acid transporter 0.1364 0.3094 0.3777
Echinococcus granulosus lamin 0.0057 0.009 0.009
Schistosoma mansoni glutamate receptor NMDA 0.0717 0.1608 0.1816
Echinococcus multilocularis excitatory amino acid transporter 3 0.1364 0.3094 0.3094
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.009 0.011
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0059 0.0094 0.0764
Loa Loa (eye worm) hypothetical protein 0.0339 0.0739 0.0739
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0094 0.0764
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0006 0.0006
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0117 0.5338
Echinococcus multilocularis NMDA receptor 0.0873 0.1966 0.1966
Echinococcus multilocularis regulator of G protein signaling 3 0.0059 0.0094 0.0094
Echinococcus multilocularis regulator of G protein signaling 3 0.0059 0.0094 0.0094
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0045 0.0403
Schistosoma mansoni nuclear hormone receptor 0.002 0.0006 0.0007
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0093 0.0093
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0117 0.0813
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0006 0.0006
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0059 0.0094 0.0106
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0605 0.1349 0.1349
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Schistosoma mansoni ap endonuclease 0.0058 0.0093 0.0105
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0219 1
Echinococcus multilocularis glutamate receptor 2 0.0917 0.2066 0.2065
Loa Loa (eye worm) hypothetical protein 0.0059 0.0094 0.0094
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0006 0.0006
Schistosoma mansoni lamin 0.0057 0.009 0.0101
Brugia malayi Receptor family ligand binding region containing protein 0.1052 0.2376 0.29
Schistosoma mansoni glutamate receptor kainate 0.0717 0.1608 0.1816
Schistosoma mansoni metabotropic glutamate receptor 0.1838 0.4183 0.4725
Echinococcus multilocularis neutral amino acid transporter A 0.1364 0.3094 0.3094
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0059 0.0094 0.0115
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0219 0.0219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0039 0.0263
Echinococcus multilocularis Excitatory amino acid transporter 0.1364 0.3094 0.3094
Echinococcus multilocularis glutamate receptor 2 0.0767 0.1722 0.1722
Loa Loa (eye worm) hypothetical protein 0.0499 0.1107 0.1107
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0059 0.0094 0.0094
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0059 0.0094 0.0106
Echinococcus multilocularis receptor type guanylyl cyclase 0.0499 0.1107 0.1106
Brugia malayi Regulator of G protein signaling domain containing protein 0.0059 0.0094 0.0115
Echinococcus granulosus glutamate receptor 4 0.005 0.0073 0.0073
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0093 0.8858
Chlamydia trachomatis glutamine binding protein 0.0395 0.0866 0.273
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0006 0.0007
Echinococcus granulosus RUN 0.0021 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0023 0.0114
Schistosoma mansoni axis inhibition protein axin 0.0059 0.0094 0.0106
Loa Loa (eye worm) hypothetical protein 0.4369 1 1
Schistosoma mansoni regulator of G protein signaling 0.0059 0.0094 0.0106
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0022 0.0022
Schistosoma mansoni thyroid hormone receptor 0.002 0.0006 0.0007
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0006 0.0006
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.001 0.0012
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0219 0.176
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0104 0.0104
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.1266 0.2869 0.2869
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0029 0.0029
Brugia malayi hypothetical protein 0.0059 0.0094 0.0115
Echinococcus granulosus lamin dm0 0.0057 0.009 0.009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0241 0.2775
Loa Loa (eye worm) serotonin transporter b 0.0059 0.0094 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0017 0.0064
Loa Loa (eye worm) glutamate receptor 1 0.0767 0.1722 0.1722
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0067 0.3036
Loa Loa (eye worm) RGS-3 protein 0.0059 0.0094 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.005 0.0073 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0045 0.0314
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0062 0.0103 0.0116
Echinococcus granulosus neutral amino acid transporter 0.1364 0.3094 0.3094
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0006 0.0006
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0219 0.0247
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0096 0.018 0.0203
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0219 0.1437
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0093 0.0837
Echinococcus granulosus receptor type guanylyl cyclase 0.0499 0.1107 0.1106
Brugia malayi phosphofructokinase 0.0113 0.0219 0.0267
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0006 0.0007
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0006 0.0006
Echinococcus granulosus regulator of G protein signaling 3 0.0059 0.0094 0.0094
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0219 0.0219
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0006 0.0006
Echinococcus granulosus FTZ F1 alpha 0.002 0.0006 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0104 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0067 0.0514
Onchocerca volvulus 0.0057 0.009 0.0271
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0006 0.0007
Wolbachia endosymbiont of Brugia malayi Na+/H+-dicarboxylate symporter 0.1364 0.3094 1
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0006 0.0007
Schistosoma mansoni glutamate receptor kainate 0.1241 0.2812 0.3176
Echinococcus granulosus atrial natriuretic peptide receptor 0.0499 0.1107 0.1106
Loa Loa (eye worm) hypothetical protein 0.0108 0.0208 0.0208
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0006 0.0006
Onchocerca volvulus 0.0075 0.0132 0.0407
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0241 1
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0605 0.1349 0.1523
Brugia malayi nuclear receptor NHR-88 0.002 0.0006 0.0007
Echinococcus granulosus sodium:dicarboxylate symporter 0.1364 0.3094 0.3094
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.1052 0.2376 0.2376
Echinococcus multilocularis Regulator of G protein signaling 20 0.0059 0.0094 0.0094
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0017 0.0063
Loa Loa (eye worm) hypothetical protein 0.0059 0.0094 0.0094
Brugia malayi PXA domain containing protein 0.0059 0.0094 0.0115
Treponema pallidum methyl-accepting chemotaxis protein (mcp2-1) 0.0263 0.0563 0.4046
Loa Loa (eye worm) RecQ helicase 0.0022 0.001 0.001
Echinococcus multilocularis lamin 0.0057 0.009 0.009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0006 0.0006
Brugia malayi PXA domain containing protein 0.0059 0.0094 0.0115
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0006 0.0007
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0399 0.0876 0.0876
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.1266 0.2869 0.2869
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.003 0.0175
Echinococcus granulosus Regulator of G protein signaling 20 0.0059 0.0094 0.0094
Echinococcus granulosus expressed protein 0.1142 0.2585 0.2585
Loa Loa (eye worm) hypothetical protein 0.005 0.0073 0.0073
Loa Loa (eye worm) glutamate receptor 2 0.0717 0.1608 0.1608
Chlamydia trachomatis glutamate symporter 0.1364 0.3094 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0094 0.0094
Onchocerca volvulus 0.0057 0.009 0.0271
Loa Loa (eye worm) hypothetical protein 0.0059 0.0094 0.0094
Echinococcus granulosus Excitatory amino acid transporter 0.1364 0.3094 0.3094
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.174 0.3959 0.3959
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0093 0.107
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0219 0.1903
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0241 0.0776
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0093 0.0093
Brugia malayi Pre-SET motif family protein 0.0439 0.0968 0.1182
Loa Loa (eye worm) hypothetical protein 0.0057 0.0091 0.0091
Schistosoma mansoni thyroid hormone receptor 0.002 0.0006 0.0007
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.003 0.1216
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0117 0.0132
Giardia lamblia GTOR 0.0047 0.0067 0.5871
Loa Loa (eye worm) hypothetical protein 0.1052 0.2376 0.2376
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0045 0.0314
Loa Loa (eye worm) hypothetical protein 0.0499 0.1107 0.1107
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.003 0.1216
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0241 0.024
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0094 0.0764
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0045 0.0314
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.1364 0.3094 0.3495
Schistosoma mansoni axis inhibition protein axin 0.0059 0.0094 0.0106
Echinococcus granulosus glutamate receptor subunit protein glur 0.0399 0.0876 0.0876
Trypanosoma cruzi extracellular receptor, putative 0.0499 0.1107 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0067 0.0601
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0067 0.0066
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0093 0.0589
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0039 0.0263
Schistosoma mansoni hypothetical protein 0.0176 0.0364 0.0411
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.0063 0.0104 0.0104
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0045 0.0403
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0219 0.0219
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0108 0.0208 0.0208
Echinococcus multilocularis axis inhibition protein axin 0.0059 0.0094 0.0094
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0717 0.1608 0.1608
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0219 0.176
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.003 0.0175
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.1364 0.3094 0.3094
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0006 0.0006
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0093 0.0753
Echinococcus multilocularis regulator of G protein signaling 7 0.0059 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0117 0.1056
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0006 0.0006
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.003 0.0175
Schistosoma mansoni z-protein (S1r protein) 0.0059 0.0094 0.0106
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0059 0.0094 0.0094
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0219 0.2527
Loa Loa (eye worm) RGC/RGC protein kinase 0.0499 0.1107 0.1107
Brugia malayi Regulator of G protein signaling domain containing protein 0.0059 0.0094 0.0115
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0006 0.0006
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0096 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus multilocularis neutral amino acid transporter A 0.1364 0.3094 0.3094
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0059 0.0094 0.0094
Echinococcus granulosus serotonin transporter 0.0059 0.0094 0.0094
Brugia malayi intermediate filament protein 0.0057 0.009 0.011
Echinococcus multilocularis tyrosine kinase 0.0499 0.1107 0.1106
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus multilocularis bloom syndrome protein 0.0022 0.001 0.001
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0067 0.0601
Echinococcus granulosus glutamate NMDA receptor subunit 0.0717 0.1608 0.1608
Schistosoma mansoni glutamate receptor kainate 0.1241 0.2812 0.3176
Loa Loa (eye worm) intermediate filament protein 0.0057 0.009 0.009
Echinococcus granulosus glutamate receptor 2 0.1266 0.2869 0.2869
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0873 0.1966 0.1966
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0395 0.0866 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) solute carrier family 6 member 4 0.0059 0.0094 0.0094
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0093 0.0113
Brugia malayi Receptor family ligand binding region containing protein 0.0499 0.1107 0.135
Echinococcus granulosus GPCR family 3 C terminal 0.0552 0.1229 0.1229
Entamoeba histolytica hypothetical protein 0.0059 0.0094 0.06
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0017 0.0064
Brugia malayi Glutamate receptor 1 precursor 0.0767 0.1722 0.2101
Onchocerca volvulus Poor gastrulation protein homolog 0.0552 0.1229 0.3959
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0552 0.1229 0.3959
Echinococcus multilocularis metabotropic glutamate receptor 5 0.4369 1 1
Echinococcus granulosus bloom syndrome protein 0.0022 0.001 0.001
Schistosoma mansoni glutamate receptor AMPA 0.0717 0.1608 0.1816
Schistosoma mansoni regulator of G protein signaling 0.0059 0.0094 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0051 0.0371
Brugia malayi hypothetical protein 0.013 0.0259 0.0315
Onchocerca volvulus 0.0499 0.1107 0.3563
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0067 0.0601
Plasmodium vivax SET domain protein, putative 0.0063 0.0104 1
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0059 0.0094 0.0094
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0117 0.0117
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0006 0.0261
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0219 0.0247
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0006 0.0006
Echinococcus multilocularis serotonin transporter 0.0059 0.0094 0.0094
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0093 1
Echinococcus granulosus neutral amino acid transporter A 0.1364 0.3094 0.3094
Schistosoma mansoni ATP-binding cassette transporter 0.0717 0.1608 0.1816
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.1052 0.2376 0.2376
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0093 0.4233
Onchocerca volvulus 0.0059 0.0094 0.0285
Brugia malayi steroid hormone receptor 0.002 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.005 0.0073 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0024 0.012
Brugia malayi hypothetical protein 0.0021 0.0006 0.0008
Brugia malayi A-kinase anchor protein 10, precursor 0.0059 0.0094 0.0115
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0091 0.0091
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0104 0.0117
Echinococcus granulosus beta-adrenergic receptor kinase 0.0059 0.0094 0.0094
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0219 0.1978
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.003 0.2363
Schistosoma mansoni serine-rich repeat protein 0.0067 0.0113 0.0127
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.003 0.0175
Echinococcus multilocularis nmda type glutamate receptor 0.0499 0.1107 0.1106
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0006 0.0007
Brugia malayi 6-phosphofructokinase 0.0113 0.0219 0.0267
Brugia malayi hypothetical protein 0.0108 0.0208 0.0254
Schistosoma mansoni loxhd1 0.0021 0.0006 0.0007
Brugia malayi Guanylyl cyclase protein 23 0.0499 0.1107 0.135
Schistosoma mansoni hypothetical protein 0.0176 0.0364 0.0411
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0024 0.012
Loa Loa (eye worm) hypothetical protein 0.0499 0.1107 0.1107
Loa Loa (eye worm) RGC/RGC protein kinase 0.0499 0.1107 0.1107
Brugia malayi hypothetical protein 0.0499 0.1107 0.135
Schistosoma mansoni regulator of G protein signaling 0.0059 0.0094 0.0106
Brugia malayi regulator of G-protein signaling rgs-7 0.0059 0.0094 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0029 0.0171
Echinococcus granulosus nmda type glutamate receptor 0.0499 0.1107 0.1106
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.003 0.0175
Schistosoma mansoni hypothetical protein 0.0067 0.0113 0.0127
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0395 0.0866 0.2798
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0093 0.048
Echinococcus multilocularis excitatory amino acid transporter 2 0.1364 0.3094 0.3094
Echinococcus granulosus intermediate filament protein 0.0057 0.009 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0039 0.0263
Brugia malayi Doublecortin family protein 0.0021 0.0006 0.0008
Onchocerca volvulus 0.0021 0.0006 0.0001
Echinococcus granulosus transcription factor Dp 1 0.004 0.0051 0.005
Echinococcus multilocularis axis inhibition protein axin 0.0059 0.0094 0.0094
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0067 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0024 0.012
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0067 0.0346
Loa Loa (eye worm) excitatory amino acid transporter 0.1364 0.3094 0.3094
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0067 0.0067
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0219 0.176
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0094 0.0764
Loa Loa (eye worm) hypothetical protein 0.0059 0.0094 0.0094
Brugia malayi Glutamate receptor 2 precursor 0.0767 0.1722 0.2101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0067 0.0514
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0219 0.0707
Brugia malayi M-phase phosphoprotein, mpp8 0.0108 0.0208 0.0254
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0241 0.024
Echinococcus granulosus excitatory amino acid transporter 3 0.1364 0.3094 0.3094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0045 0.0314
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0094 0.0106
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.3083 0.7045 0.86
Brugia malayi Pre-SET motif family protein 0.0063 0.0104 0.0127
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0006 0.0006
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.174 0.3959 0.3959
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0094 0.0106
Schistosoma mansoni hypothetical protein 0.035 0.0763 0.0861
Schistosoma mansoni hypothetical protein 0.0552 0.1229 0.1388
Treponema pallidum sodium- and chloride- dependent transporter 0.0059 0.0094 0.0492
Loa Loa (eye worm) hypothetical protein 0.0499 0.1107 0.1107
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.003 0.2363
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0499 0.1107 0.1106
Schistosoma mansoni lipoxygenase 0.0057 0.0091 0.0103
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0241 0.2775
Loa Loa (eye worm) hypothetical protein 0.0059 0.0094 0.0094
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0093 0.0837
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.003 0.1216
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0017 0.0063
Onchocerca volvulus 0.0108 0.0208 0.0654
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0004 0.0167
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0059 0.0094 0.0106
Brugia malayi metabotropic glutamate receptor type 2 0.1838 0.4183 0.5106
Echinococcus granulosus tyrosine kinase 0.0499 0.1107 0.1106
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0241 0.2172
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0499 0.1107 0.135
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0124 0.0244 0.0275
Treponema pallidum glutamate/aspartate transporter 0.0605 0.1349 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0039 0.0263
Schistosoma mansoni ap endonuclease 0.0058 0.0093 0.0105
Schistosoma mansoni hypothetical protein 0.0021 0.0006 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0039 0.0263
Echinococcus granulosus nmda type glutamate receptor 0.0744 0.1669 0.1669
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0093 0.0093
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0605 0.1349 0.1349
Schistosoma mansoni polycystin 1-related 0.0021 0.0006 0.0007
Echinococcus granulosus axis inhibition protein axin 0.0059 0.0094 0.0094
Echinococcus granulosus Excitatory amino acid transporter 0.1364 0.3094 0.3094
Loa Loa (eye worm) hypothetical protein 0.0059 0.0094 0.0094
Schistosoma mansoni protein kinase 0.0499 0.1107 0.125
Echinococcus granulosus geminin 0.0176 0.0364 0.0364
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0099 0.0098
Brugia malayi ecdysteroid receptor 0.002 0.0006 0.0007
Loa Loa (eye worm) glutamate receptor 0.3582 0.8193 0.8193
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.0499 0.1107 0.1107
Echinococcus multilocularis expressed protein 0.1142 0.2585 0.2585
Echinococcus multilocularis beta adrenergic receptor kinase 0.0059 0.0094 0.0094
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0219 0.1903
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.387 0.8853 1
Echinococcus multilocularis nmda type glutamate receptor 0.0744 0.1669 0.1669
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.003 0.2859
Echinococcus multilocularis sodium:dicarboxylate symporter 0.1364 0.3094 0.3094
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0006 0.0007
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0395 0.0866 0.6341
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.003 0.0175
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0129 0.0256 0.0256
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0067 0.0346
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0045 0.0314
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0093 0.0299
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0219 0.1978
Echinococcus granulosus voltage dependent calcium channel subunit 0.0284 0.0612 0.0611
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0075 0.0132 0.0149
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0219 0.1903
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0006 0.0007
Schistosoma mansoni rab6-interacting 0.0021 0.0006 0.0007
Leishmania major extracellular receptor, putative 0.0499 0.1107 1
Loa Loa (eye worm) glutamate receptor 0.1339 0.3036 0.3036
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0094 0.0764
Echinococcus multilocularis regulator of G protein signaling 0.0059 0.0094 0.0094
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0006 0.0006
Echinococcus multilocularis regulator of G protein signaling 7 0.0059 0.0094 0.0094
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.035 0.0763 0.0762
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0023 0.0114
Entamoeba histolytica hypothetical protein 0.0499 0.1107 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.009 0.009
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0059 0.0094 0.0094
Schistosoma mansoni tyrosine kinase 0.0499 0.1107 0.125
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0094 0.0764
Schistosoma mansoni regulator of G protein signaling 0.0059 0.0094 0.0106
Entamoeba histolytica hypothetical protein 0.0059 0.0094 0.06
Onchocerca volvulus 0.0021 0.0006 0.0001
Echinococcus multilocularis geminin 0.0176 0.0364 0.0364
Schistosoma mansoni coup transcription factor 0.002 0.0006 0.0007
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.035 0.0763 0.0762
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0031 0.0192
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus regulator of G protein signaling 7 0.0059 0.0094 0.0094
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0059 0.0094 0.0106
Treponema pallidum glutamate transporter 0.0605 0.1349 1
Brugia malayi Cytochrome P450 family protein 0.0075 0.0133 0.0162
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0219 1
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0499 0.1107 0.1107
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0552 0.1229 0.15
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.003 0.0175
Loa Loa (eye worm) hypothetical protein 0.0499 0.1107 0.1107
Echinococcus multilocularis GPCR, family 3, C terminal 0.0552 0.1229 0.1229
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0006 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0006 0.0007
Echinococcus granulosus regulator of G protein signaling 3 0.0059 0.0094 0.0094
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0093 0.0753
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0104 0.0104
Entamoeba histolytica hypothetical protein 0.0059 0.0094 0.06
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0022 0.0022
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.1268 0.2873 0.2873
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0395 0.0866 0.6341
Echinococcus granulosus axis inhibition protein axin 0.0059 0.0094 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0006 0.0007
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0067 0.0601
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0017 0.0064
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0006 0.0007
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0006 0.0006
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0104 0.4319
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0873 0.1966 0.1966
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0873 0.1966 0.1966
Echinococcus multilocularis excitatory amino acid transporter 2 0.1364 0.3094 0.3094
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0022
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0096 0.018 0.018
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0395 0.0866 0.273
Loa Loa (eye worm) PXA domain-containing protein 0.0059 0.0094 0.0094
Schistosoma mansoni sodium/chloride dependent transporter 0.0059 0.0094 0.0106
Schistosoma mansoni lipoxygenase 0.0021 0.0006 0.0007
Loa Loa (eye worm) RGC/RGC protein kinase 0.0499 0.1107 0.1107
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0059 0.0094 0.0094
Echinococcus granulosus excitatory amino acid transporter 2 0.1364 0.3094 0.3094
Schistosoma mansoni rab6-interacting 0.0021 0.0006 0.0007
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0241 0.2775
Echinococcus granulosus regulator of G protein signaling 7 0.0059 0.0094 0.0094
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0006 0.0006

Activities

Activity type Activity value Assay description Source Reference
Relative stability (binding) = 119 % Effect on microtubule stabilization isolated from bovine brain ChEMBL. 9871773
Relative stability (binding) = 119 % Effect on microtubule stabilization isolated from bovine brain ChEMBL. 9871773

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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