Detailed information for compound 41911

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 444.398 | Formula: C19H20N6O7
  • H donors: 5 H acceptors: 10 LogP: -1.26 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CCC(C(=O)O)NC(=O)c1ccc(cc1)N1CCC(C1=O)c1nnc(nc1O)N
  • InChi: 1S/C19H20N6O7/c20-19-22-16(29)14(23-24-19)11-7-8-25(17(11)30)10-3-1-9(2-4-10)15(28)21-12(18(31)32)5-6-13(26)27/h1-4,11-12H,5-8H2,(H,21,28)(H,26,27)(H,31,32)(H3,20,22,24,29)
  • InChiKey: BPPDXEYNAGIVIS-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.0082 0.0274
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Loa Loa (eye worm) RecQ helicase 0.002 0.0018 0.0064
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0052 0.0173
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.0366 0.158
Entamoeba histolytica hypothetical protein 0.0187 0.0373 0.1559
Schistosoma mansoni nuclear receptor 0.0024 0.0025 0.0084
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0111 0.0394
Plasmodium vivax SET domain protein, putative 0.0032 0.0043 0.0041
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0016 0.0053
Leishmania major chloride channel protein, putative 0.002 0.0018 0.0058
Trichomonas vaginalis BRCA1-associated protein, putative 0.0025 0.0027 0.0109
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0018 0.0064
Echinococcus multilocularis thioredoxin glutathione reductase 0.0037 0.0054 0.0062
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0025 0.0084
Echinococcus multilocularis neuroglian 0.0048 0.0078 0.009
Loa Loa (eye worm) hypothetical protein 0.0431 0.0893 0.3172
Loa Loa (eye worm) hypothetical protein 0.0109 0.0207 0.0735
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0168 0.0332 0.1107
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0006
Brugia malayi hypothetical protein 0.0027 0.0031 0.0111
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0102 0.0434
Echinococcus granulosus histone deacetylase 8 0.0552 0.115 0.3837
Brugia malayi Pre-SET motif family protein 0.0032 0.0043 0.0152
Loa Loa (eye worm) hypothetical protein 0.0156 0.0307 0.109
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.0082 0.0274
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.001 0.0035
Brugia malayi 6-phosphofructokinase 0.0112 0.0214 0.0759
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0042 0.0064 0.0062
Trypanosoma brucei SNF1-related protein kinases, putative 0.0048 0.0077 0.0267
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Toxoplasma gondii NEK kinase 0.0021 0.002 0.0019
Mycobacterium tuberculosis Conserved protein 0.002 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.003 0.0038 0.0133
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0025 0.0027 0.0089
Schistosoma mansoni ran 0.0022 0.0021 0.007
Trypanosoma cruzi NIMA-related kinase, putative 0.0021 0.002 0.0066
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.026 0.0528 0.1761
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0018 0.0058
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0036 0.0051 0.0175
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0055 0.0184
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.0082 0.0292
Loa Loa (eye worm) chloride channel 3 0.002 0.0018 0.0064
Loa Loa (eye worm) hypothetical protein 0.0059 0.01 0.0354
Plasmodium vivax glycogen synthase kinase 3, putative 0.0051 0.0082 0.0081
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0.0014 0.0012
Brugia malayi hypothetical protein 0.0431 0.0893 0.3172
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0032
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0184 0.0366 0.122
Echinococcus multilocularis expressed conserved protein 0.0285 0.0582 0.0671
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0042 0.0064 0.0126
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.2322 0.4918 1
Schistosoma mansoni DNA ligase IV 0.006 0.0102 0.0339
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0022 0.0073
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0025 0.022
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0021 0.0019
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0048 0.0077 0.0267
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Brugia malayi nuclear hormone receptor 0.0024 0.0025 0.009
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0051 0.0082 0.0095
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.002 0.0018 0.0033
Echinococcus granulosus cyclin dependent kinase 5 0.0048 0.0076 0.0253
Entamoeba histolytica hypothetical protein 0.0036 0.0052 0.0157
Brugia malayi Carboxylesterase family protein 0.0198 0.0396 0.1408
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.011 0.0209 0.0737
Brugia malayi hypothetical protein 0.0044 0.0068 0.024
Brugia malayi hypothetical protein 0.0033 0.0046 0.0163
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0016 0.0019
Toxoplasma gondii histone deacetylase HDAC5 0.0552 0.115 0.1149
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.0082 0.0292
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0184 0.0366 0.122
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0107 0.0202 0.0407
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0114 0.0217 0.0438
Schistosoma mansoni chloride channel protein 0.002 0.0018 0.006
Echinococcus multilocularis serine:threonine protein kinase Nek1 0.0017 0.0011 0.0013
Plasmodium falciparum importin beta, putative 0.003 0.0038 0.0036
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.002 0.0018 0.006
Loa Loa (eye worm) histone deacetylase 0.1334 0.2815 1
Trichomonas vaginalis CAMK family protein kinase 0.0021 0.002 0.008
Echinococcus multilocularis casein kinase ii subunit beta 0.0036 0.0051 0.0059
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0038 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0021 0.002 0.008
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0179 0.0355 0.0353
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.002 0.0018 0.0058
Onchocerca volvulus 0.006 0.0102 0.0884
Brugia malayi Histone deacetylase family protein 0.1334 0.2815 1
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.054 0.2338
Toxoplasma gondii histone lysine-specific demethylase 0.0066 0.0115 0.0113
Echinococcus granulosus histone deacetylase 6 0.1334 0.2815 0.9389
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0036 0.0051 0.0175
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0015 0.0054
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0187 0.0373 0.1319
Leishmania major mitochondrial DNA polymerase beta 0.0294 0.06 0.2128
Entamoeba histolytica hypothetical protein 0.0024 0.0026 0.0042
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0033 0.0046 0.0153
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0872 0.183 0.3719
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0006
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0039 0.0037
Brugia malayi polk-prov protein 0.0087 0.0159 0.0565
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.002 0.0018 0.0058
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0111
Schistosoma mansoni titin 0.0016 0.0009 0.003
Trypanosoma cruzi histone deacetylase 1, putative 0.1094 0.2304 0.8186
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0078
Echinococcus granulosus acetylcholinesterase 0.0198 0.0396 0.1321
Echinococcus granulosus hemicentin 1 0.0022 0.0022 0.0073
Toxoplasma gondii IQ calmodulin-binding motif domain-containing protein 0.0014 0.0004 0.0003
Brugia malayi RNA binding protein 0.0129 0.0249 0.0885
Leishmania major acetyl-CoA synthetase, putative 0.0042 0.0064 0.0221
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0346 0.1493
Loa Loa (eye worm) CAMK protein kinase 0.0016 0.0009 0.0032
Toxoplasma gondii histone deacetylase HDAC4 0.0552 0.115 0.1149
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.0159 0.056
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0168 0.0332 0.0383
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0053 0.0182
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0249 0.0831
Schistosoma mansoni ran 0.0022 0.0021 0.007
Onchocerca volvulus 0.0018 0.0014 0.012
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0016 0.0054
Echinococcus granulosus lysine specific histone demethylase 1A 0.0066 0.0115 0.0384
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0095 0.0177 0.0204
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0076 0.0322
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0047 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.006 0.0102 0.0361
Plasmodium falciparum NIMA related kinase 2 0.0021 0.002 0.0019
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0066 0.0115 0.0384
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.0025
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0424 0.0878 0.3805
Echinococcus granulosus histone deacetylase 7 0.1334 0.2815 0.9389
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 0.0059 0.01 0.0335
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0332 0.1106
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0076 0.0264
Brugia malayi AMP-binding enzyme family protein 0.0042 0.0064 0.0227
Echinococcus granulosus lachesin 0.0022 0.0022 0.0073
Trypanosoma brucei DNA polymerase eta, putative 0.0134 0.0259 0.0916
Schistosoma mansoni histone deacetylase 4 5 0.1334 0.2815 0.9389
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0016 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.009
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0107 0.0203 0.0234
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0249 0.0831
Echinococcus granulosus muscleblind protein 0.0606 0.1266 0.4222
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0022 0.0078
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0018 0.0071
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0076 0.027
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0163
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0093 0.0173 0.0349
Mycobacterium ulcerans transcriptional regulator 0.002 0.0018 0.0016
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0068 0.0067
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0223 0.0221
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0107 0.0203 0.0678
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0016 0.0401
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0266 0.054 0.1918
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0018 0.0016
Echinococcus multilocularis 0.0066 0.0115 0.0133
Echinococcus granulosus titin 0.0016 0.0009 0.003
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0042 0.0064 0.0126
Trichomonas vaginalis replication factor C large subunit, putative 0.006 0.0102 0.0434
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0031 0.0111
Loa Loa (eye worm) hypothetical protein 0.026 0.0528 0.1876
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.0109 0.0207 0.0735
Echinococcus multilocularis Niemann Pick C1 protein 0.0304 0.0621 0.0717
Loa Loa (eye worm) AUR protein kinase 0.0168 0.0332 0.1178
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0055 0.0184
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0051 0.0049
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.002 0.0018 0.006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0198 0.0396 0.1321
Echinococcus multilocularis neuroglian 0.0022 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0606 0.1266 0.4497
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0018 0.0071
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0025 0.0084
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.0082 0.0095
Echinococcus multilocularis Protein lozenge 0.0054 0.009 0.0103
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0051 0.0154
Trichomonas vaginalis histone deacetylase, putative 0.1094 0.2304 1
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0051 0.0444
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.016 0.0564
Echinococcus granulosus microtubule associated protein 2 0.142 0.2998 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Plasmodium falciparum acyl-CoA synthetase 0.0107 0.0202 0.02
Brugia malayi Ets-domain containing protein 0.0074 0.0133 0.0473
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.0082 0.0292
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0272 0.0554 0.1849
Trypanosoma brucei DNA polymerase IV, putative 0.0161 0.0317 0.1121
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0028 0.0033 0.0111
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0028 0.0033 0.0118
Loa Loa (eye worm) loechrig isoform VII 0.0227 0.0457 0.1625
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0424 0.0878 0.3805
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0292 0.0597 0.0595
Plasmodium falciparum thioredoxin reductase 0.0037 0.0053 0.0051
Echinococcus multilocularis histone deacetylase 6 0.1334 0.2815 0.3245
Echinococcus multilocularis titin 0.0016 0.0009 0.001
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0104 0.012
Trichomonas vaginalis DNA polymerase eta, putative 0.0161 0.0317 0.1369
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0235 0.0474 0.1582
Leishmania major GTP-binding protein, putative 0.0022 0.0021 0.0068
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.01 0.0356
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0016 0.0062
Leishmania major protein kinase, putative 0.0021 0.002 0.0066
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0085 0.0157 0.0181
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0042 0.0064 0.0227
Onchocerca volvulus Histone deacetylase 10 homolog 0.0552 0.115 1
Trichomonas vaginalis CAMK family protein kinase 0.0021 0.002 0.008
Schistosoma mansoni protein kinase subunit beta 0.0059 0.01 0.0335
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0111
Echinococcus multilocularis BRCA1 associated protein 0.0025 0.0027 0.0031
Loa Loa (eye worm) histone deacetylase 7A 0.1334 0.2815 1
Entamoeba histolytica recQ family helicase, putative 0.002 0.0018 0.001
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0143 0.0279 0.0277
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0064
Echinococcus granulosus defective proboscis extension response 0.0036 0.0052 0.0174
Brugia malayi serine/threonine-protein kinase 6 0.0168 0.0332 0.1178
Echinococcus multilocularis para nitrobenzyl esterase 0.0033 0.0046 0.0053
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0028 0.0033 0.0032
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0026 0.0085
Echinococcus multilocularis muscleblind protein 0.0606 0.1266 0.1459
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.0213 0.0431
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.011 0.0209 0.0743
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0084 0.0153 0.0276
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Mycobacterium tuberculosis Carboxylesterase LipT 0.0033 0.0046 0.009
Brugia malayi Pre-SET motif family protein 0.0216 0.0435 0.1544
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0424 0.0878 0.3767
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0042 0.0064 0.0213
Leishmania major hypothetical protein, conserved,leucine-rich repeat protein, putative 0.0014 0.0004 0.0009
Plasmodium falciparum flap endonuclease 1 0.0052 0.0085 0.0084
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.0082 0.0714
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0084 0.0153 0.0308
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0009 0.003
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0025 0.0027 0.0089
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0009 0.0032
Onchocerca volvulus 0.0015 0.0008 0.0065
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0082 0.0292
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.1094 0.2304 1
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0045 0.0161
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0082 0.0285
Brugia malayi Peroxidasin 0.0022 0.0022 0.0078
Loa Loa (eye worm) Csnk2b protein 0.0036 0.0051 0.0181
Brugia malayi 6-phosphofructokinase 0.0112 0.0213 0.0758
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0028 0.0033 0.0118
Loa Loa (eye worm) hypothetical protein 0.0124 0.024 0.0851
Brugia malayi SWIRM domain containing protein 0.0066 0.0115 0.0409
Loa Loa (eye worm) runx1 0.0054 0.009 0.0319
Brugia malayi nuclear receptor RXR 0.0024 0.0025 0.009
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.009
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0213 0.092
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0078
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Brugia malayi protein C24B5.3 0.0018 0.0014 0.0049
Schistosoma mansoni cpg binding protein 0.0062 0.0107 0.0358
Schistosoma mansoni lozenge 0.0054 0.009 0.0299
Echinococcus granulosus histone deacetylase 6 0.1358 0.2867 0.9563
Trypanosoma brucei DNA damage repair protein, putative 0.0033 0.0046 0.0156
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0082 0.0274
Echinococcus multilocularis 5' AMP activated protein kinase subunit beta 1 0.0059 0.01 0.0116
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0048 0.0077 0.0267
Echinococcus granulosus replication factor c subunit 1 0.006 0.0102 0.0339
Echinococcus multilocularis protein kinase shaggy 0.0051 0.0082 0.0095
Brugia malayi Patched related family protein 12 0.0018 0.0014 0.0049
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0068 0.0067
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0022 0.0078
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0068 0.0228
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0082 0.0292
Brugia malayi nuclear receptor NHR-67 0.0024 0.0025 0.009
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0039 0.0037
Schistosoma mansoni nephrin 0.0048 0.0078 0.0259
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.002 0.0018 0.0016
Loa Loa (eye worm) histone deacetylase 11 0.0552 0.115 0.4087
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0021 0.0024
Loa Loa (eye worm) chloride channel protein 7 0.002 0.0018 0.0064
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Plasmodium falciparum glutathione reductase 0.0037 0.0053 0.0051
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0008 0.0027
Mycobacterium ulcerans dehydrogenase 0.0066 0.0115 0.0113
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.006 0.0102 0.0355
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0168 0.0332 0.033
Schistosoma mansoni histone deacetylase 0.1094 0.2304 0.7687
Entamoeba histolytica protein kinase , putative 0.0168 0.0332 0.138
Schistosoma mansoni flap endonuclease-1 0.0047 0.0075 0.0249
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.0082 0.0274
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.002 0.0018 0.006
Echinococcus granulosus cpg binding protein 0.0062 0.0107 0.0358
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0076 0.0322
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0231 0.0817
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0022 0.0078
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.0102 0.0355
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0025 0.0029
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0039 0.0162
Echinococcus granulosus protein kinase shaggy 0.0051 0.0082 0.0275
Mycobacterium tuberculosis Possible oxidoreductase 0.0066 0.0115 0.0231
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.002 0.0018 0.006
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0018 0.0071
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0055 0.0172
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Plasmodium falciparum histone deacetylase, putative 0.1334 0.2815 0.2813
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0048 0.0077 0.0088
Plasmodium vivax histone deacetylase, putative 0.0552 0.115 0.1149
Loa Loa (eye worm) carboxylesterase 0.0033 0.0046 0.0163
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0052 0.0085 0.0297
Onchocerca volvulus 0.0033 0.0046 0.0398
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.0033 0.0137
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0143 0.0279 0.0563
Brugia malayi CLC chloride channel protein 0.002 0.0018 0.0064
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0066 0.0115 0.0198
Loa Loa (eye worm) IMP dehydrogenase 1 0.002 0.0018 0.0064
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0021 0.0074
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.0213 0.0753
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0162
Giardia lamblia Kinase, CAMK CAMKL 0.0048 0.0077 0.0326
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0082 0.0292
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0053 0.0104
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0082 0.0274
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0022 0.0078
Brugia malayi histone deacetylase 11 0.0552 0.115 0.4087
Schistosoma mansoni acetylcholinesterase 0.0033 0.0046 0.0153
Onchocerca volvulus 0.01 0.0187 0.1627
Schistosoma mansoni alkaline phosphatase 0.0168 0.0332 0.1107
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.0082 0.0274
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0039 0.0037
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0085 0.0157 0.0522
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.013 0.0252 0.0896
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0028 0.0033 0.0076
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0189 0.0382
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0042 0.0064 0.0221
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0043 0.0143
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0042 0.0064 0.0126
Trichomonas vaginalis glutaminase, putative 0.0563 0.1174 0.509
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0048 0.0076 0.0264
Schistosoma mansoni titin 0.0022 0.0022 0.0073
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0033 0.0046 0.0044
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0025 0.009
Onchocerca volvulus 0.0059 0.01 0.087
Schistosoma mansoni casein kinase II beta subunit 0.0036 0.0051 0.017
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0424 0.0878 0.3805
Schistosoma mansoni ap endonuclease 0.0019 0.0016 0.0053
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0015 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0085 0.0157 0.0556
Onchocerca volvulus 0.0033 0.0046 0.0398
Loa Loa (eye worm) hypothetical protein 0.0066 0.0115 0.0409
Loa Loa (eye worm) hypothetical protein 0.0087 0.0159 0.0565
Echinococcus multilocularis carboxylesterase 5A 0.0198 0.0396 0.0457
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0028 0.0033 0.0111
Trypanosoma brucei histone deacetylase 3 0.1334 0.2815 1
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0187 0.0373 0.1324
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.002 0.0018 0.0033
Brugia malayi N-terminal motif family protein 0.0176 0.0349 0.1239
Brugia malayi latrophilin 2 splice variant baaae 0.0205 0.0411 0.146
Leishmania major UDP-galactopyranose mutase 0.0066 0.0115 0.0403
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.002 0.0018 0.0033
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0009 0.003
Trypanosoma cruzi aurora B kinase, putative 0.0168 0.0332 0.1173
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0027 0.0031 0.011
Loa Loa (eye worm) hypothetical protein 0.0107 0.0202 0.0717
Schistosoma mansoni cell adhesion molecule 0.0047 0.0074 0.0248
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0143 0.0279 0.0563
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0294 0.06 0.2128
Trichomonas vaginalis rotamase, putative 0.0032 0.0044 0.0182
Loa Loa (eye worm) hypothetical protein 0.0066 0.0115 0.0409
Echinococcus granulosus GPCR family 2 0.0095 0.0177 0.0589
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0316 0.0647 0.2297
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0111
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0028 0.0033 0.0118
Leishmania major histone deacetylase, putative 0.1334 0.2815 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.0292
Brugia malayi phosphofructokinase 0.0112 0.0213 0.0758
Echinococcus multilocularis tyrosine protein kinase otk 0.0022 0.0022 0.0025
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0025 0.0084
Trypanosoma cruzi DNA polymerase kappa, putative 0.0161 0.0317 0.1121
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0028 0.0033 0.0118
Echinococcus multilocularis histone deacetylase 7 0.1334 0.2815 0.3245
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0163
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0163
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0009 0.003
Onchocerca volvulus 0.0024 0.0025 0.022
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0042 0.0064 0.0093
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.002 0.0018 0.0033
Giardia lamblia DINP protein human, muc B family 0.0121 0.0231 0.0998
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0055 0.0196
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0018 0.0016
Brugia malayi nuclear receptor NHR-88 0.0024 0.0025 0.009
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0064
Onchocerca volvulus 0.0018 0.0014 0.012
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0016 0.0056
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.002 0.0018 0.0016
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative 0.0065 0.0113 0.0111
Toxoplasma gondii patched family protein 0.0018 0.0014 0.0012
Plasmodium falciparum protoporphyrinogen oxidase 0.0066 0.0115 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0077 0.0256
Brugia malayi RE40412p 0.0015 0.0008 0.0027
Loa Loa (eye worm) hypothetical protein 0.0176 0.0349 0.1239
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.0213 0.2417
Trypanosoma cruzi GMP reductase 0.002 0.0018 0.0058
Echinococcus granulosus acetylcholinesterase 0.0198 0.0396 0.1321
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0085 0.0083
Trichomonas vaginalis histone deacetylase, putative 0.1094 0.2304 1
Echinococcus multilocularis alkaline phosphatase 0.0168 0.0332 0.0383
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0938 0.1971 0.1969
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0006
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0028 0.0033 0.0038
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0025 0.0084
Loa Loa (eye worm) hypothetical protein 0.0107 0.0202 0.0717
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0346 0.1493
Toxoplasma gondii PfMNL-2 CISD1 family iron-sulfur protein, putative 0.0015 0.0008 0.0006
Plasmodium falciparum glycogen synthase kinase 3 0.0051 0.0082 0.0081
Schistosoma mansoni histone deacetylase hda2 0.1358 0.2867 0.9563
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0332 0.1433
Giardia lamblia Kinase, CAMK CAMKL 0.0048 0.0077 0.0326
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0064 0.0062
Brugia malayi Carboxylesterase family protein 0.0033 0.0046 0.0163
Trypanosoma cruzi chloride channel protein, putative 0.002 0.0018 0.0058
Brugia malayi ancient conserved domain protein 4 0.002 0.0018 0.0064
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0114 0.0217 0.0406
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0039 0.0037
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0085 0.0295
Schistosoma mansoni roundabout 0.0022 0.0022 0.0073
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0055 0.019
Trichomonas vaginalis rotamase, putative 0.0033 0.0045 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.013 0.0252 0.1088
Echinococcus granulosus snurportin 1 0.0316 0.0647 0.2157
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0028 0.0033 0.0032
Echinococcus multilocularis Niemann Pick C1 protein 0.0434 0.0899 0.1037
Echinococcus granulosus histone deacetylase 6 0.1334 0.2815 0.9389
Schistosoma mansoni cpg binding protein 0.0062 0.0107 0.0358
Plasmodium falciparum protein kinase 5 0.0048 0.0076 0.0074
Toxoplasma gondii hypothetical protein 0.0047 0.0075 0.0074
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0042 0.0064 0.0062
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0021 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0042 0.0064 0.0227
Brugia malayi hypothetical protein 0.0018 0.0014 0.0049
Entamoeba histolytica hypothetical protein 0.006 0.0102 0.0375
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0187 0.0373 0.1319
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0042 0.0064 0.0126
Trypanosoma brucei DNA polymerase kappa, putative 0.0161 0.0317 0.1121
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0021 0.002 0.0066
Brugia malayi Flap endonuclease-1 0.0052 0.0085 0.0303
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0027 0.0025
Echinococcus multilocularis acetylcholinesterase 0.0198 0.0396 0.0457
Echinococcus granulosus lysine specific histone demethylase 1A 0.0066 0.0115 0.0384
Echinococcus granulosus BC026374 protein S09 family 0.0033 0.0046 0.0153
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0213 0.0758
Brugia malayi Voltage gated chloride channel family protein 0.002 0.0018 0.0064
Echinococcus multilocularis microtubule associated protein 2 0.142 0.2998 0.3457
Brugia malayi loechrig isoform VII 0.0227 0.0457 0.1625
Schistosoma mansoni chloride channel protein 0.002 0.0018 0.006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0032
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0009 0.003
Echinococcus multilocularis histone deacetylase 1 0.1094 0.2304 0.2657
Echinococcus multilocularis peroxidasin 0.0022 0.0022 0.0025
Schistosoma mansoni amine oxidase 0.0066 0.0115 0.0384
Trichomonas vaginalis CAMK family protein kinase 0.0021 0.002 0.008
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.002 0.0067
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.006 0.0102 0.0434
Schistosoma mansoni hypothetical protein 0.0085 0.0157 0.0522
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0068 0.0289
Treponema pallidum Mg2+ transport protein (mgtE) 0.002 0.0018 0.0186
Brugia malayi AMP-binding enzyme family protein 0.0143 0.0279 0.099
Trichomonas vaginalis helicase, putative 0.0013 0.0003 0.0006
Brugia malayi Histone deacetylase family protein 0.1334 0.2815 1
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0042 0.0064 0.0062
Echinococcus multilocularis dnaJ subfamily B 0.084 0.1763 0.2033
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Schistosoma mansoni 3-dehydroquinate synthase 0.0114 0.0217 0.0723
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Brugia malayi Patched related family protein 4 0.0018 0.0014 0.0049
Loa Loa (eye worm) hypothetical protein 0.0066 0.0115 0.0409
Schistosoma mansoni chloride channel protein 0.002 0.0018 0.006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0066 0.0115 0.0231
Onchocerca volvulus Protein patched homolog 0.0018 0.0014 0.012
Loa Loa (eye worm) acetyltransferase 0.015 0.0293 0.1041
Brugia malayi hypothetical protein 0.0018 0.0014 0.0049
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.0033 0.0137
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0085 0.0157 0.0522
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0424 0.0878 0.3805
Schistosoma mansoni hypothetical protein 0.0023 0.0024 0.008
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0076 0.0253
Echinococcus multilocularis hemicentin 1 0.0022 0.0022 0.0025
Trichomonas vaginalis histone deacetylase, putative 0.1094 0.2304 1
Echinococcus granulosus serine:threonine protein kinase Nek1 0.0017 0.0011 0.0037
Plasmodium vivax histone deacetylase 2, putative 0.1334 0.2815 0.2813
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0039 0.0037
Brugia malayi jmjC domain containing protein 0.0016 0.0009 0.0032
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0189 0.0382
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.009
Toxoplasma gondii histone deacetylase HDAC2 0.1094 0.2304 0.2303
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.006 0.0102 0.2832
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0095 0.0177 0.0589
Brugia malayi Amyloid A4 extracellular domain containing protein 0.034 0.0698 0.2479
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0578 0.1204 0.4018
Schistosoma mansoni septate junction protein 0.0022 0.0022 0.0073
Echinococcus granulosus histone deacetylase 3 0.1094 0.2304 0.7687
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0042 0.0064 0.0126
Brugia malayi nuclear hormone receptor 0.0051 0.0082 0.0292
Schistosoma mansoni hypothetical protein 0.0347 0.0714 0.2383
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0042 0.0064 0.0221
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0021 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0066 0.0115 0.0409
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0143 0.0279 0.0277
Echinococcus multilocularis bloom syndrome protein 0.002 0.0018 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.0082 0.0292
Brugia malayi AMP-binding enzyme family protein 0.0042 0.0064 0.0227
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0025 0.0029
Schistosoma mansoni histone deacetylase hda2 0.0552 0.115 0.3837
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0085 0.0295
Leishmania major 4-coumarate:coa ligase-like protein 0.0143 0.0279 0.0985
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0009 0.0007
Trichomonas vaginalis histone deacetylase, putative 0.1094 0.2304 1
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0047 0.0074 0.0248
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0064 0.0062
Brugia malayi nuclear receptor NHR-88 0.0051 0.0082 0.0292
Echinococcus granulosus dnaJ subfamily B 0.084 0.1763 0.5881
Treponema pallidum hemolysin (tlyC) 0.002 0.0018 0.0186
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0031 0.0105
Echinococcus multilocularis acetylcholinesterase 0.0198 0.0396 0.0457
Trichomonas vaginalis spcc417.12 protein, putative 0.0033 0.0046 0.0191
Plasmodium vivax hypothetical protein, conserved 0.0066 0.0115 0.0113
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0039 0.0037
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.002 0.0018 0.006
Trichomonas vaginalis ran, putative 0.0022 0.0021 0.0083
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0021 0.002 0.0066
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.011 0.0209 0.0737
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0018 0.0058
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0036 0.0052 0.0174
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.0082 0.0274
Plasmodium vivax importin-beta 2, putative 0.003 0.0038 0.0036
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0042 0.0064 0.0221
Onchocerca volvulus Glucosylceramidase homolog 0.0174 0.0346 0.3004
Loa Loa (eye worm) hypothetical protein 0.0107 0.0202 0.0717
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0036 0.0052 0.006
Loa Loa (eye worm) hypothetical protein 0.006 0.0102 0.0361
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.0293 0.0338
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0028 0.0033 0.0032
Mycobacterium ulcerans hypothetical protein 0.0033 0.0046 0.0044
Entamoeba histolytica protein kinase, putative 0.0187 0.0373 0.1559
Onchocerca volvulus 0.0156 0.0307 0.2666
Schistosoma mansoni cell adhesion molecule 0.0022 0.0022 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0006
Echinococcus granulosus roundabout 2 0.0022 0.0022 0.0073
Echinococcus granulosus BRCA1 associated protein 0.0025 0.0027 0.0089
Giardia lamblia Kinase, NEK 0.0021 0.002 0.008
Loa Loa (eye worm) carboxylesterase 0.0198 0.0396 0.1408
Onchocerca volvulus 0.0024 0.0025 0.022
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0104 0.0346
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0187 0.0373 0.1319
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0009 0.0026
Onchocerca volvulus 0.002 0.0018 0.0157
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.0159 0.056
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0022 0.0078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0052 0.0186
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0042 0.0064 0.0126
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0184 0.0366 0.122
Echinococcus multilocularis flap endonuclease 1 0.0052 0.0085 0.0098
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0018 0.0071
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0044 0.0042
Toxoplasma gondii histone kinase SNF1, putative 0.0048 0.0077 0.0075
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0042 0.0064 0.021
Brugia malayi Importin beta-1 subunit 0.003 0.0038 0.0133
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0051 0.0082 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0102 0.0434
Onchocerca volvulus 0.0042 0.0064 0.0555
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.002 0.0018 0.0071
Echinococcus granulosus H:Cl exchange transporter 7 0.002 0.0018 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0055 0.0233
Brugia malayi hypothetical protein 0.0018 0.0014 0.0049
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0028 0.0033 0.0137
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0266 0.054 0.1918
Brugia malayi hypothetical protein 0.0066 0.0115 0.0409
Schistosoma mansoni hypothetical protein 0.0126 0.0242 0.0808
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0006
Brugia malayi Carboxylesterase family protein 0.0033 0.0046 0.0163
Schistosoma mansoni DNA helicase recq5 0.002 0.0018 0.006
Onchocerca volvulus 0.0015 0.0008 0.0065
Loa Loa (eye worm) hypothetical protein 0.0042 0.0064 0.0227
Toxoplasma gondii zinc finger cdgsh type protein 0.0015 0.0008 0.0006
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.0082 0.0274
Echinococcus granulosus peroxidasin 0.0022 0.0022 0.0073
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0025 0.009
Echinococcus multilocularis roundabout 2 0.0022 0.0022 0.0025
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0038 0.0127
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Loa Loa (eye worm) hypothetical protein 0.006 0.0102 0.0361
Schistosoma mansoni ets-related 0.0226 0.0456 0.1521
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0033 0.0046 0.009
Echinococcus granulosus Protein patched homolog 1 0.013 0.0252 0.0841
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0051 0.0082 0.0286
Giardia lamblia Aurora kinase 0.0168 0.0332 0.1433
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0028 0.0033 0.0038
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0044 0.0149
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0292 0.0597 0.0595
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.0213 0.0212
Echinococcus granulosus cyclin dependent kinase 0.0048 0.0076 0.0253
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0022 0.0022 0.0191
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0249 0.0831
Echinococcus multilocularis histone deacetylase 0.1334 0.2815 0.3245
Entamoeba histolytica Flap nuclease, putative 0.0052 0.0085 0.0304
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0051 0.0049
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0042 0.0064 0.0062
Mycobacterium ulcerans acyl-CoA synthetase 0.0143 0.0279 0.0277
Echinococcus multilocularis tar DNA binding protein 0.0129 0.0249 0.0287
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0008 0.0006
Onchocerca volvulus Tyrosine kinase homolog 0.0487 0.1012 0.8793
Brugia malayi AMP-binding enzyme family protein 0.0042 0.0064 0.0227
Giardia lamblia Hypothetical protein 0.002 0.0018 0.0071
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.03 0.0613 0.2177
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0213 0.0758
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0082 0.0292
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0025 0.0027 0.0025
Chlamydia trachomatis GutQ/KpsF family sugar-phosphate isomerase 0.002 0.0018 0.0016
Toxoplasma gondii chorismate synthase, putative 0.4709 1 1
Trypanosoma brucei unspecified product 0.0148 0.0289 0.102
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.0082 0.0095
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0015 0.0008 0.0006
Leishmania major protein kinase, putative 0.0168 0.0332 0.1173
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0184 0.0366 0.13
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0028 0.0033 0.0118
Brugia malayi hypothetical protein 0.0033 0.0046 0.0162
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0346 0.1493
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0042 0.0064 0.0221
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0036 0.0051 0.0101
Loa Loa (eye worm) TK protein kinase 0.0017 0.001 0.0035
Loa Loa (eye worm) hypothetical protein 0.0183 0.0364 0.1292
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0008 0.0027
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Echinococcus granulosus expressed protein 0.0033 0.0045 0.0151
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0009 0.0026
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.054 0.2338
Schistosoma mansoni coup transcription factor 0.0051 0.0082 0.0274
Brugia malayi protein unc-22 0.0016 0.0009 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0161 0.0317 0.1121
Trichomonas vaginalis STE family protein kinase 0.0021 0.002 0.008
Brugia malayi DKFZp564C0469 protein 0.006 0.0102 0.0361
Onchocerca volvulus Protein patched homolog 0.0018 0.0014 0.012
Echinococcus granulosus intestinal type alkaline phosphatase 0.0168 0.0332 0.1107
Schistosoma mansoni chromosome transmission fidelity factor 0.006 0.0102 0.0339
Loa Loa (eye worm) hypothetical protein 0.0036 0.0052 0.0186
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0022 0.0078
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0033 0.0046 0.0153
Trypanosoma brucei NIMA-related protein kinase 0.0021 0.002 0.0066
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.007 0.0123 0.0121
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.0293 0.0978
Mycobacterium ulcerans DNA polymerase IV 0.0161 0.0317 0.0315
Giardia lamblia Flap structure-specific endonuclease 0.0052 0.0085 0.0363
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0042 0.0064 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0015
Giardia lamblia Hypothetical protein 0.0028 0.0033 0.0137
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0036 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0036 0.0052 0.0186
Schistosoma mansoni hypothetical protein 0.0316 0.0647 0.2157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.0082 0.0292
Giardia lamblia Casein kinase II beta chain 0.0036 0.0051 0.0214
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0227 0.0457 0.1526
Brugia malayi Immunoglobulin I-set domain containing protein 0.0522 0.1086 0.3858
Brugia malayi ImpB/MucB/SamB family protein 0.0134 0.0259 0.0921
Toxoplasma gondii patched family protein 0.0018 0.0014 0.0012
Schistosoma mansoni hypothetical protein 0.0036 0.0052 0.0173
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0179 0.0355 0.0353
Schistosoma mansoni apoptosis regulator bax 0.0085 0.0157 0.0522
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0028 0.0033 0.0111
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0042 0.0064 0.0221
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0051 0.0082 0.0275
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0025 0.009
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0162
Loa Loa (eye worm) hypothetical protein 0.0143 0.0279 0.099
Trichomonas vaginalis antibiotic synthetase, putative 0.0042 0.0064 0.027
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0009 0.001
Brugia malayi MH2 domain containing protein 0.0123 0.0237 0.0842
Loa Loa (eye worm) hypothetical protein 0.006 0.0102 0.0361
Schistosoma mansoni cell adhesion molecule 0.0022 0.0022 0.0073
Leishmania major DNA polymerase eta, putative 0.0134 0.0259 0.0916
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0184 0.0366 0.0422
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0213 0.0712
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Toxoplasma gondii IMP dehydrogenas 0.002 0.0018 0.0016
Trypanosoma cruzi UDP-galactopyranose mutase 0.0066 0.0115 0.0403
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0163
Brugia malayi Patched protein homolog 1 0.0018 0.0014 0.0049
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.0292
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0043 0.0049
Brugia malayi putative serine/threonine kinase SADA gamma 0.0048 0.0077 0.0273
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0042 0.0064 0.0227
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0078
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0168 0.0332 0.0383
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0102 0.0434
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0085 0.0083
Echinococcus granulosus neuroglian 0.0048 0.0078 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.0082 0.0292
Echinococcus granulosus flap endonuclease 1 0.0052 0.0085 0.0285
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0126 0.0243 0.0812
Brugia malayi glutaminase DH11.1 0.0563 0.1174 0.4171
Loa Loa (eye worm) latrophilin receptor protein 2 0.0095 0.0177 0.0627
Brugia malayi topoisomerase 0.006 0.0102 0.0361
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0068 0.0289
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.0292
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0022 0.0022 0.0025
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0006
Brugia malayi hypothetical protein 0.0052 0.0085 0.0301
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0024 0.008
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0026 0.0104
Echinococcus multilocularis expressed protein 0.0033 0.0045 0.0052
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0033 0.0112
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0187 0.0373 0.1319
Brugia malayi ancient conserved domain protein 2 0.002 0.0018 0.0064
Plasmodium vivax glutathione reductase, putative 0.0037 0.0053 0.0051
Trypanosoma brucei chrX additional, unordered contigs 0.0033 0.0046 0.0156
Mycobacterium ulcerans glutaminase 0.0563 0.1174 0.1172
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0474 0.1582
Plasmodium vivax histone deacetylase 1, putative 0.1094 0.2304 0.2303
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0121 0.0231 0.0467
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0257 0.0521 0.1739
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0022 0.0073
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0076 0.0322
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0021 0.0068
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0018 0.0016
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.026 0.0528 0.1761
Loa Loa (eye worm) hypothetical protein 0.0107 0.0202 0.0717
Mycobacterium ulcerans hypothetical protein 0.002 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.006 0.0102 0.0361
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0111 0.037
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0055 0.0064
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.0082 0.0274
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0257 0.0521 0.0601
Loa Loa (eye worm) oxidoreductase 0.0042 0.0064 0.0227
Brugia malayi ecdysone receptor 0.0024 0.0025 0.009
Onchocerca volvulus 0.0018 0.0014 0.012
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0018 0.0064
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0043 0.0143
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.016 0.0564
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0039 0.0037
Loa Loa (eye worm) RNA binding protein 0.0129 0.0249 0.0885
Loa Loa (eye worm) hypothetical protein 0.0052 0.0085 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0006
Leishmania major hypothetical protein, unknown function 0.0015 0.0008 0.0021
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.0082 0.0095
Leishmania major trypanothione reductase 0.0037 0.0053 0.0182
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.0082 0.0292
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0006
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.002 0.0018 0.0021
Plasmodium falciparum replication factor C subunit 1, putative 0.006 0.0102 0.01
Loa Loa (eye worm) hypothetical protein 0.0036 0.0052 0.0186
Loa Loa (eye worm) TAR-binding protein 0.0129 0.0249 0.0885
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.002 0.0018 0.0462
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0424 0.0878 0.3805
Mycobacterium ulcerans monoamine oxidase 0.0066 0.0115 0.0113
Leishmania major DNA damage repair protein, putative 0.0033 0.0046 0.0156
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.002 0.0018 0.006
Echinococcus granulosus AMPK beta subunit 0.011 0.0209 0.0697
Echinococcus granulosus titin 0.0016 0.0009 0.003
Toxoplasma gondii CBS family protein 0.002 0.0018 0.0016
Schistosoma mansoni protein kinase subunit beta 0.011 0.0209 0.0697
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0078
Entamoeba histolytica hypothetical protein 0.0036 0.0052 0.0157
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0076 0.027
Leishmania major serine/threonine-protein kinase, putative 0.0021 0.002 0.0066
Loa Loa (eye worm) hypothetical protein 0.0036 0.0052 0.0186
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0031 0.0105
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0064 0.0062
Trypanosoma brucei unspecified product 0.0074 0.0132 0.0464
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0114 0.0217 0.0438
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.009
Loa Loa (eye worm) hypothetical protein 0.1094 0.2304 0.8187
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0084 0.0153 0.0308
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0025 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.0161 0.0317 0.1121
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.054 0.2338
Loa Loa (eye worm) histone deacetylase 3 0.1094 0.2304 0.8187
Brugia malayi ecdysteroid receptor 0.0051 0.0082 0.0292
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.006 0.0102 0.0361
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0042 0.0064 0.0126
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0046 0.0156
Schistosoma mansoni hypothetical protein 0.0085 0.0157 0.0522
Mycobacterium tuberculosis Probable oxidoreductase 0.0093 0.0173 0.0349
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0076 0.0262
Toxoplasma gondii Amylo-alpha-1,6-glucosidase 0.0014 0.0004 0.0003
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0055 0.019
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0076 0.0322
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0045 0.0189
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0143 0.0279 0.0277
Mycobacterium ulcerans hypothetical protein 0.002 0.0018 0.0016
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.0082 0.0274
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.054 0.2338
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0424 0.0878 0.3805
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0082 0.0274
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0025 0.0084
Schistosoma mansoni cell adhesion molecule 0.0022 0.0022 0.0073
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0018 0.006
Schistosoma mansoni nuclear receptor 0.0024 0.0025 0.0084
Loa Loa (eye worm) glutaminase 2 0.0563 0.1174 0.4171
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.002 0.0018 0.0462
Trypanosoma cruzi chloride channel protein, putative 0.002 0.0018 0.0058
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0051 0.0444
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0009 0.0026
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0051 0.0049
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0082 0.0292
Mycobacterium ulcerans cystathionine beta-synthase 0.002 0.0018 0.0016
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.002 0.0018 0.0058
Toxoplasma gondii serine/threonine specific protein phosphatase 0.0014 0.0004 0.0003
Schistosoma mansoni amine oxidase 0.0066 0.0115 0.0384
Onchocerca volvulus 0.0042 0.0064 0.0555
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.006 0.0102 0.01
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0043 0.0143
Plasmodium vivax acyl-CoA synthetase, putative 0.0107 0.0202 0.02
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0213 0.0712
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0093 0.0173 0.0349
Mycobacterium ulcerans acetyl-CoA synthetase 0.0042 0.0064 0.0062
Toxoplasma gondii exonuclease III APE 0.0019 0.0016 0.0014
Chlamydia trachomatis dehyroquinate synthase 0.0114 0.0217 0.0215
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.06 0.2128
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0022 0.0025
Brugia malayi Thioredoxin reductase 0.0037 0.0053 0.0188
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.026 0.0528 0.0609
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0107 0.0203 0.0722
Plasmodium vivax replication factor C subunit 1, putative 0.006 0.0102 0.01
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0052 0.0085 0.0297
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0002 0.0006
Echinococcus multilocularis dual specificity 0.0187 0.0373 0.043
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0025 0.0027 0.0089
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0017 0.001 0.0033
Echinococcus granulosus H:Cl exchange transporter 3 0.002 0.0018 0.006
Trypanosoma cruzi histone deacetylase, putative 0.0552 0.115 0.4084
Schistosoma mansoni BC026374 protein (S09 family) 0.0033 0.0046 0.0153
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0048 0.0077 0.0075
Schistosoma mansoni protein kinase subunit beta 0.0014 0.0004 0.0014
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0093 0.0173 0.0317
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0025 0.0027 0.0089
Trypanosoma brucei AIR9-like protein 0.0014 0.0004 0.0009
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0053 0.0188
Schistosoma mansoni hypothetical protein 0.0205 0.0411 0.1371
Leishmania major 4-coumarate:coa ligase-like protein 0.0143 0.0279 0.0985
Echinococcus multilocularis dna polymerase eta 0.0134 0.0259 0.0299
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0013 0.0003 0.0002
Mycobacterium ulcerans hypothetical protein 0.0143 0.0279 0.0277
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0066 0.0115 0.0113
Echinococcus granulosus Immunoglobulin 0.0036 0.0052 0.0174
Schistosoma mansoni histone deacetylase 0.1094 0.2304 0.7687
Schistosoma mansoni ap endonuclease 0.0019 0.0016 0.0053
Brugia malayi ImpB/MucB/SamB family protein 0.0107 0.0203 0.0722
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0025 0.022
Trypanosoma cruzi DNA damage repair protein, putative 0.0033 0.0046 0.0156
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0055 0.0233
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.0133 0.0473
Schistosoma mansoni glutaminase 0.0563 0.1174 0.3916
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0064 0.0062
Echinococcus multilocularis AMPK beta subunit 0.011 0.0209 0.0241
Echinococcus granulosus aurora kinase A 0.0168 0.0332 0.1106
Echinococcus multilocularis protoporphyrinogen oxidase 0.0066 0.0115 0.0133
Entamoeba histolytica deoxycytidyl transferase, putative 0.0107 0.0203 0.0819
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0063 0.0216
Brugia malayi Protein kinase domain containing protein 0.0187 0.0373 0.1324
Trypanosoma cruzi leucine rich repeat protein, putative 0.0014 0.0004 0.0009
Toxoplasma gondii thioredoxin reductase 0.0037 0.0053 0.0051
Echinococcus granulosus dna polymerase kappa 0.0161 0.0317 0.1057
Schistosoma mansoni hypothetical protein 0.084 0.1763 0.5881
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0114 0.0217 0.0215
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0292 0.0597 0.0595
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0016 0.0009 0.0032
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0042 0.0064 0.0126
Schistosoma mansoni microtubule-associated protein tau 0.142 0.2998 1
Echinococcus granulosus dna polymerase eta 0.0134 0.0259 0.0865
Schistosoma mansoni hypothetical protein 0.0126 0.0242 0.0808
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0064
Trichomonas vaginalis set domain proteins, putative 0.0246 0.0498 0.2155
Echinococcus granulosus twitchin 0.0053 0.0087 0.0289
Trypanosoma brucei trypanothione reductase 0.0037 0.0053 0.0182
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0189 0.0382
Brugia malayi Carboxylesterase family protein 0.0033 0.0046 0.0163
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0168 0.0332 0.0382
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0168 0.0332 0.1106
Onchocerca volvulus 0.0018 0.0014 0.012
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0031 0.0111
Brugia malayi AMP-binding enzyme family protein 0.0042 0.0064 0.0227
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0082 0.035
Plasmodium falciparum serine/threonine protein kinase KIN 0.0048 0.0077 0.0075
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0048 0.0077 0.0267
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0052 0.0173
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0055 0.0184
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.0033 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0082 0.0292
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0063 0.0216
Leishmania major hypothetical protein, conserved 0.0052 0.0085 0.0295
Chlamydia trachomatis protoporphyrinogen oxidase 0.0066 0.0115 0.0113
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0025 0.0084
Loa Loa (eye worm) hypothetical protein 0.016 0.0315 0.1118
Onchocerca volvulus 0.0033 0.0046 0.0398
Echinococcus multilocularis cyclin dependent kinase 5 0.0048 0.0076 0.0088
Leishmania major importin beta-1 subunit, putative 0.0024 0.0026 0.0085
Wolbachia endosymbiont of Brugia malayi hemolysin 0.002 0.0018 0.0462
Echinococcus multilocularis histone deacetylase 6 0.1334 0.2815 0.3245
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0009 0.003
Onchocerca volvulus 0.0143 0.0279 0.2422
Echinococcus granulosus conserved hypothetical protein 0.0015 0.0008 0.0025
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0016 0.0053
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0028 0.0033 0.0032
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0009 0.0007
Schistosoma mansoni importin beta-1 0.003 0.0038 0.0125
Echinococcus multilocularis twitchin 0.0016 0.0009 0.001
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0042 0.0064 0.0062
Loa Loa (eye worm) AUR protein kinase 0.0168 0.0332 0.1178
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0168 0.0332 0.138
Leishmania major hypothetical protein, conserved 0.011 0.0209 0.0737
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0077 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0102 0.0434
Mycobacterium tuberculosis Conserved hypothetical protein 0.0107 0.0203 0.041
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0025 0.0029
Loa Loa (eye worm) flap endonuclease-1 0.0052 0.0085 0.0303
Trypanosoma brucei DNA polymerase kappa, putative 0.0161 0.0317 0.1121
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0227 0.0457 0.1979
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.0082 0.0292
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.0292
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0095 0.0177 0.0627
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.0082 0.0292
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0018 0.0016
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0025 0.0084
Echinococcus multilocularis sterol regulatory element binding protein 0.013 0.0252 0.0291
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0048 0.0077 0.0273
Entamoeba histolytica protein kinase domain containing protein 0.0168 0.0332 0.138
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0042 0.0064 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0006
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0107 0.0202 0.02
Trichomonas vaginalis brca1-associated protein, putative 0.0025 0.0027 0.0109
Echinococcus multilocularis snurportin 1 0.0316 0.0647 0.0746
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0143 0.0279 0.0277
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.0082 0.0714
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.002 0.0018 0.0058
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0051 0.0082 0.0095
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0066 0.0115 0.0113
Brugia malayi Steroid receptor seven-up type 2 0.0051 0.0082 0.0292
Schistosoma mansoni hypothetical protein 0.0272 0.0554 0.1849
Echinococcus multilocularis thyroid hormone receptor alpha 0.0051 0.0082 0.0095
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0111
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0022 0.0078
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0052 0.0085 0.0297
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0018 0.0058
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.006 0.0102 0.0171
Brugia malayi Histone deacetylase 1 0.1094 0.2304 0.8187
Brugia malayi jmjC domain containing protein 0.0064 0.0111 0.0394
Echinococcus multilocularis protein patched 0.013 0.0252 0.0291
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.0082 0.0292
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0033 0.0046 0.009
Brugia malayi jmjC domain containing protein 0.0061 0.0104 0.0369
Leishmania major guanosine monophosphate reductase 0.002 0.0018 0.0058
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0018 0.0064
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4085 0.8672 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0008 0.0027
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0042 0.0064 0.0062
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0424 0.0878 0.3767
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0063 0.0216
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.002 0.0018 0.0033
Brugia malayi Myosin head containing protein 0.0018 0.0014 0.0049
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0082 0.029
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0168 0.0332 0.138
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0033 0.0046 0.0053
Onchocerca volvulus 0.047 0.0976 0.8485
Loa Loa (eye worm) hypothetical protein 0.0043 0.0067 0.0238
Schistosoma mansoni hypothetical protein 0.0095 0.0177 0.0589
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.0292
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0016 0.0014
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0021 0.0083
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0163
Mycobacterium ulcerans acyl-CoA synthetase 0.0143 0.0279 0.0277
Toxoplasma gondii hypothetical protein 0.0014 0.0004 0.0003
Echinococcus granulosus sterol regulatory element binding protein 0.013 0.0252 0.0841
Loa Loa (eye worm) hypothetical protein 0.0143 0.0279 0.099
Brugia malayi serine/threonine kinase 12 0.0168 0.0332 0.1178
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.011 0.0209 0.0743
Echinococcus granulosus casein kinase ii subunit beta 0.0036 0.0051 0.017
Schistosoma mansoni terminal deoxycytidyl transferase 0.0107 0.0203 0.0678
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0112 0.0213 0.0399
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0021 0.0019
Brugia malayi CBS domain containing protein 0.002 0.0018 0.0064
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0227 0.0457 0.0527
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0078
Schistosoma mansoni hypothetical protein 0.0347 0.0714 0.2383
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0028 0.0033 0.0076
Onchocerca volvulus 0.0431 0.0893 0.7762
Leishmania major histone deacetylase, putative 0.1094 0.2304 0.8186
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.006 0.0255
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.002 0.0018 0.0071
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0076 0.0088
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.006 0.0102 0.0434
Brugia malayi jmjC domain containing protein 0.0016 0.0009 0.0032
Loa Loa (eye worm) hypothetical protein 0.0268 0.0544 0.1934
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0271 0.0956
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0082 0.029
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0235 0.0474 0.0547
Brugia malayi hypothetical protein 0.0156 0.0307 0.109
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0052 0.0085 0.0084
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.0293 0.1041
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.0435 0.1544
Loa Loa (eye worm) apoptosis regulator protein 0.0085 0.0157 0.0556
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0055 0.019
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0095 0.0177 0.0204
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0025 0.0029
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.009
Brugia malayi jmjC domain containing protein 0.0016 0.0009 0.0032
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0076 0.0264
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0076 0.0264
Brugia malayi RNA, U transporter 1 0.0084 0.0154 0.0546
Mycobacterium ulcerans chorismate synthase 0.4709 1 1
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0025 0.0027 0.0232
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0008 0.0009
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.002 0.0018 0.0058
Entamoeba histolytica serine/threonine protein kinase, putative 0.0048 0.0077 0.0266
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0189 0.0382
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0082 0.0274
Loa Loa (eye worm) patched family protein 0.0018 0.0014 0.0049
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.054 0.2338
Schistosoma mansoni histone deacetylase 1 2 3 0.0552 0.115 0.3837
Onchocerca volvulus 0.0109 0.0207 0.1799
Loa Loa (eye worm) fli-1 protein 0.0226 0.0456 0.162
Loa Loa (eye worm) hypothetical protein 0.0095 0.0177 0.0627
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0107 0.0203 0.0678
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0039 0.0037
Giardia lamblia DNA damage repair protein 0.0033 0.0046 0.019
Brugia malayi hypothetical protein 0.0024 0.0025 0.009
Mycobacterium tuberculosis Conserved protein 0.002 0.0018 0.0033
Schistosoma mansoni DNA polymerase IV / kappa 0.0033 0.0046 0.0152
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0009 0.0032
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0076 0.0262
Loa Loa (eye worm) hypothetical protein 0.0042 0.0064 0.0227
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Echinococcus multilocularis Immunoglobulin 0.0036 0.0052 0.006
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0373 0.1243
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0082 0.0292
Echinococcus granulosus FTZ F1 alpha 0.0051 0.0082 0.0274
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0332 0.1433
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0064 0.0062
Schistosoma mansoni hypothetical protein 0.0095 0.0177 0.0589
Plasmodium vivax protein kinase Crk2 0.0048 0.0076 0.0074
Schistosoma mansoni topbp1 0.006 0.0102 0.0339
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.0082 0.0095
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0184 0.0366 0.13
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0016 0.0018
Echinococcus multilocularis replication factor c subunit 1 0.006 0.0102 0.0117
Entamoeba histolytica hypothetical protein 0.0036 0.0052 0.0157
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Leishmania major hypothetical protein, conserved 0.0025 0.0027 0.0089
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0184 0.0366 0.122
Plasmodium falciparum serine/threonine protein kinase, putative 0.0168 0.0332 0.033
Loa Loa (eye worm) hypothetical protein 0.01 0.0187 0.0665
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.009
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0022 0.0078
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.006 0.0102 0.0375
Trypanosoma cruzi DNA polymerase kappa, putative 0.0161 0.0317 0.1121
Entamoeba histolytica protein kinase, putative 0.0168 0.0332 0.138
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0028 0.0033 0.0038
Echinococcus granulosus para nitrobenzyl esterase 0.0033 0.0046 0.0153
Loa Loa (eye worm) hypothetical protein 0.0044 0.0068 0.024
Brugia malayi hypothetical protein 0.0036 0.0052 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0006
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.0082 0.0292
Echinococcus multilocularis neuroligin 0.0033 0.0046 0.0053
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0051 0.0175
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0033 0.0046 0.0153
Plasmodium vivax chorismate synthase 0.4709 1 1
Plasmodium vivax JmjC domain containing protein 0.0016 0.0009 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.013 0.0252 0.0896
Echinococcus granulosus H:Cl exchange transporter 4 0.002 0.0018 0.006
Brugia malayi Fibronectin type III domain containing protein 0.0036 0.0052 0.0186
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Echinococcus granulosus roundabout 2 0.0022 0.0022 0.0073
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0076 0.0264
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0043 0.0041
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0026 0.0104
Mycobacterium ulcerans acyl-CoA synthetase 0.0143 0.0279 0.0277
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.0102 0.0355
Mycobacterium ulcerans hypothetical protein 0.002 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Brugia malayi glutathione reductase 0.0037 0.0053 0.0188
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.011 0.0209 0.0737
Loa Loa (eye worm) hypothetical protein 0.0064 0.011 0.0391
Toxoplasma gondii ck2 beta subunit 0.0036 0.0051 0.0049
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0063 0.0216
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0048 0.0076 0.0264
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0003 0.0006
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0095 0.0177 0.0589
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0042 0.0064 0.0227
Leishmania major acetyl-CoA synthetase, putative 0.0042 0.0064 0.0221
Brugia malayi Latrophilin receptor protein 2 0.0095 0.0177 0.0627
Plasmodium falciparum DNA repair protein REV1, putative 0.0033 0.0046 0.0044
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.0237 0.0842
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0051 0.0154
Leishmania major histone deacetylase, putative 0.1334 0.2815 1
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0022 0.0022 0.0025
Brugia malayi jmjC domain containing protein 0.0016 0.0009 0.0032
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0104 0.0346
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0008 0.0009
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0085 0.0295
Loa Loa (eye worm) hypothetical protein 0.0048 0.0077 0.0273
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0206 0.0414 0.0477
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0082 0.0292
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0107 0.0202 0.0717
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0111 0.037
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0085 0.0157 0.0522
Brugia malayi protein C24B5.3 0.0018 0.0014 0.0049
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0025 0.009
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0292 0.0597 0.1182
Trypanosoma brucei cdc2-related kinase 1 0.0048 0.0076 0.0264
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.0082 0.0292
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0076 0.0088
Toxoplasma gondii aurora kinase 0.0168 0.0332 0.033
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.0082 0.0274
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0235 0.0474 0.1685
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.009
Schistosoma mansoni hypothetical protein 0.0126 0.0242 0.0808
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0025 0.0027 0.0047
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0332 0.1433
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0048 0.0077 0.0267
Trichomonas vaginalis flap endonuclease-1, putative 0.0052 0.0085 0.0363
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.009
Mycobacterium ulcerans oxidoreductase 0.0066 0.0115 0.0113
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0143 0.0279 0.0532
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.06 0.2128
Trichomonas vaginalis histone deacetylase, putative 0.1094 0.2304 1
Entamoeba histolytica protein kinase, putative 0.0187 0.0373 0.1559
Echinococcus granulosus dual specificity 0.0187 0.0373 0.1243
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0042 0.0064 0.0221
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.2322 0.4918 1
Brugia malayi hypothetical protein 0.0024 0.0025 0.009
Onchocerca volvulus 0.0042 0.0064 0.0555
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Schistosoma mansoni gabp alpha 0.0074 0.0133 0.0444
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0051 0.0154
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0048 0.0076 0.0074
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0025 0.0084
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.002 0.0018 0.0021
Brugia malayi Patched related family protein 10 0.0018 0.0014 0.0049
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0124 0.0238 0.0795
Echinococcus multilocularis aurora kinase A 0.0168 0.0332 0.0382
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0082 0.035
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0009 0.003
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0026 0.0104
Loa Loa (eye worm) hypothetical protein 0.0047 0.0074 0.0264
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.006 0.0195
Echinococcus granulosus tumor protein p63 0.0682 0.1427 0.476
Schistosoma mansoni hypothetical protein 0.0087 0.016 0.0535
Brugia malayi RE40412p 0.0015 0.0008 0.0027
Trypanosoma brucei histone deacetylase 4 0.1334 0.2815 1
Schistosoma mansoni hypothetical protein 0.0085 0.0157 0.0522
Echinococcus granulosus tyrosine protein kinase otk 0.0022 0.0022 0.0073
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0078
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0043 0.0049
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0271 0.0956
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0016 0.0062
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.002 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0346 0.1493
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.0082 0.0292
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0043 0.0143
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0213 0.092
Leishmania major hypothetical protein, conserved 0.0016 0.0009 0.0026
Brugia malayi hypothetical protein 0.0027 0.0031 0.0111
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0033 0.0046 0.0153
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.0082 0.0274
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.0082 0.0292
Plasmodium falciparum protein MAM3, putative 0.002 0.0018 0.0016
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0025 0.0084
Leishmania major DNA polymerase kappa, putative 0.0121 0.0231 0.0817
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0346 0.1493
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0009 0.003
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0143 0.0279 0.0532
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0046 0.0156
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0052 0.006
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.0082 0.0274
Schistosoma mansoni brca1-associated protein (brap2) 0.0025 0.0027 0.0089
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0066 0.0115 0.0133
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0938 0.1971 0.1969
Schistosoma mansoni DNA polymerase eta 0.0134 0.0259 0.0865
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0066 0.0115 0.0113
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Trypanosoma brucei histone deacetylase 2 0.0552 0.115 0.4084
Brugia malayi hypothetical protein 0.006 0.0102 0.0361
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0055 0.0233
Trypanosoma cruzi histone deacetylase 1, putative 0.1094 0.2304 0.8186
Leishmania major inosine-5-monophosphate dehydrogenase 0.002 0.0018 0.0058
Echinococcus multilocularis roundabout 2 0.0022 0.0022 0.0025
Chlamydia trachomatis DNA ligase 0.006 0.0102 0.01
Loa Loa (eye worm) glutathione reductase 0.0037 0.0053 0.0188
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0284 0.0948
Echinococcus granulosus alkaline phosphatase 0.0168 0.0332 0.1107
Trypanosoma cruzi histone deacetylase, putative 0.1334 0.2815 1
Echinococcus multilocularis lachesin 0.0022 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0997
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0009 0.0007
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.006 0.0102 0.0434
Loa Loa (eye worm) acetylcholinesterase 1 0.0198 0.0396 0.1408
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0082 0.035
Onchocerca volvulus 0.0032 0.0043 0.0373
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.002 0.0018 0.0033
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0016 0.0056
Plasmodium vivax acetyl-CoA synthetase, putative 0.0042 0.0064 0.0062
Trypanosoma brucei aurora B kinase 0.0168 0.0332 0.1173
Trypanosoma cruzi protein kinase, putative 0.0017 0.0011 0.0034
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0066 0.0115 0.0113
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0021 0.002 0.0066
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0022 0.0022 0.0073
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0064 0.0062
Entamoeba histolytica protein kinase domain containing protein 0.0187 0.0373 0.1559
Onchocerca volvulus 0.0016 0.0009 0.0079
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0168 0.0332 0.1107
Echinococcus multilocularis BC026374 protein (S09 family) 0.0033 0.0046 0.0053
Trypanosoma brucei DNA damage repair protein, putative 0.0033 0.0046 0.0156
Trypanosoma brucei protein kinase, putative 0.0051 0.0082 0.0286
Schistosoma mansoni nephrin 0.0022 0.0022 0.0073
Mycobacterium tuberculosis Probable reductase 0.0084 0.0153 0.0308
Brugia malayi Calcitonin receptor-like protein seb-1 0.03 0.0613 0.2177
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0027
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0021 0.007
Echinococcus multilocularis protein dispatched 1 0.0149 0.0291 0.0336
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0082 0.035
Brugia malayi tailless protein 0.0024 0.0025 0.009
Plasmodium falciparum histone deacetylase 1 0.1094 0.2304 0.2303
Echinococcus granulosus expressed conserved protein 0.0285 0.0582 0.1942
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.0082 0.0095
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0163
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0016 0.0018
Toxoplasma gondii hypothetical protein 0.0018 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.009
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0022 0.0022 0.0025
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0036 0.0052 0.0174
Onchocerca volvulus Alicorn homolog 0.0096 0.0179 0.1559
Schistosoma mansoni cellular tumor antigen P53 0.01 0.0187 0.0624
Loa Loa (eye worm) hypothetical protein 0.0183 0.0364 0.1292
Loa Loa (eye worm) pigment dispersing factor receptor c 0.03 0.0613 0.2177
Leishmania major CBS domain protein, conserved 0.002 0.0018 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0346 0.1493
Brugia malayi serine/threonine protein kinase 6 0.0168 0.0332 0.1178
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0168 0.0332 0.0383
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0162
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0009 0.001
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0018 0.0021
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0785 0.1646 0.3321
Echinococcus granulosus neuroglian 0.0022 0.0022 0.0073
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0042 0.0064 0.0093
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0213 0.0863
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.0237 0.0842
Brugia malayi Muscleblind-like protein 0.0606 0.1266 0.4497
Trypanosoma cruzi histone deacetylase, putative 0.1334 0.2815 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0022 0.0078
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0033 0.0046 0.0191
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0016 0.005
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.002 0.0018 0.0462
Trypanosoma cruzi GMP reductase 0.002 0.0018 0.0058
Loa Loa (eye worm) carboxylesterase 0.0033 0.0046 0.0163
Brugia malayi hypothetical protein 0.006 0.0102 0.0361
Toxoplasma gondii histone deacetylase HDAC3 0.1094 0.2304 0.2303
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0044 0.0149
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0066 0.0115 0.0113
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0039 0.0162
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0018 0.0064
Echinococcus granulosus contactin 0.0022 0.0022 0.0073
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0055 0.0184
Schistosoma mansoni neuroglian 0.0022 0.0022 0.0073
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0085 0.0157 0.0556
Loa Loa (eye worm) hypothetical protein 0.0044 0.0068 0.024
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0039 0.0037
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Brugia malayi Ets-domain containing protein 0.0074 0.0133 0.0473
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0022 0.0078
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0048 0.0076 0.027
Trypanosoma cruzi chloride channel protein, putative 0.002 0.0018 0.0058
Brugia malayi histone deacetylase 3 (HD3) 0.1094 0.2304 0.8187
Giardia lamblia Fructose-bisphosphate aldolase 0.0424 0.0878 0.3805
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0033 0.0112
Echinococcus multilocularis histone deacetylase 3 0.1094 0.2304 0.2657
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0084 0.0153 0.0308
Schistosoma mansoni rotamase 0.0033 0.0045 0.0151
Echinococcus multilocularis GPCR, family 2 0.0095 0.0177 0.0204
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0082 0.0292
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0042 0.0064 0.0062
Plasmodium vivax hypothetical protein, conserved 0.0066 0.0115 0.0113
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.0366 0.158
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0046 0.0156
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0021 0.002 0.0066
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0042 0.0064 0.0126
Brugia malayi RNA recognition motif domain containing protein 0.0129 0.0249 0.0885
Plasmodium vivax histone deacetylase, putative 0.1334 0.2815 0.2813
Entamoeba histolytica hypothetical protein 0.0036 0.0052 0.0157
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.054 0.2338
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.0102 0.0355
Schistosoma mansoni tyrosine kinase 0.0027 0.0032 0.0107
Mycobacterium ulcerans DNA polymerase IV 0.0161 0.0317 0.0315
Echinococcus granulosus thioredoxin glutathione reductase 0.0037 0.0054 0.018
Brugia malayi conserved hypotetical protein 0.0024 0.0025 0.009
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0016 0.0014
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0048 0.0077 0.0267
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0064 0.0062
Entamoeba histolytica acyl-coA synthetase, putative 0.0143 0.0279 0.1148
Schistosoma mansoni septate junction protein 0.0022 0.0022 0.0073
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.002 0.0018 0.0058
Loa Loa (eye worm) hypothetical protein 0.0036 0.0052 0.0186
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0042 0.0064 0.0062
Trichomonas vaginalis antibiotic synthetase, putative 0.0042 0.0064 0.027
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0009 0.0032
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0213 0.092
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0084 0.0153 0.0308
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.0292
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.002 0.0018 0.0058
Echinococcus multilocularis hemicentin 1 0.0022 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0198 0.0396 0.1408
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0044 0.0149
Brugia malayi Carboxylesterase family protein 0.0033 0.0046 0.0163
Onchocerca volvulus 0.0051 0.0082 0.0715
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0018 0.0021
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0055 0.0184
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0249 0.0831
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0028 0.0033 0.0032
Trypanosoma cruzi histone deacetylase, putative 0.1334 0.2815 1
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0039 0.0101
Toxoplasma gondii zinc finger CDGSH-type domain-containing protein 0.0015 0.0008 0.0006
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.1094 0.2304 1
Brugia malayi hypothetical protein 0.0036 0.0052 0.0184
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Brugia malayi AMP-binding enzyme family protein 0.0143 0.0279 0.099
Plasmodium vivax patched family protein, putative 0.0018 0.0014 0.0012
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.002 0.0018 0.0021
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0055 0.0064
Giardia lamblia Replication factor C, subunit 1 0.006 0.0102 0.0434
Brugia malayi CXXC zinc finger family protein 0.0059 0.01 0.0356
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0179 0.0355 0.403
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.009
Schistosoma mansoni hypothetical protein 0.0126 0.0242 0.0808
Schistosoma mansoni patched 1 0.013 0.0252 0.0841
Trypanosoma cruzi DNA polymerase kappa, putative 0.0161 0.0317 0.1121
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.002 0.0018 0.0021
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0028 0.0033 0.0118
Loa Loa (eye worm) hypothetical protein 0.0782 0.1639 0.5822
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0179 0.0355 1
Onchocerca volvulus 0.0042 0.0064 0.0555
Loa Loa (eye worm) hypothetical protein 0.0143 0.0279 0.099
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0051 0.0082 0.0286
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0025 0.009
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0522 0.1086 0.3858
Schistosoma mansoni topbp1 0.006 0.0102 0.0339
Trypanosoma cruzi UDP-galactopyranose mutase 0.0066 0.0115 0.0403
Brugia malayi Csnk2b protein 0.0036 0.0051 0.0181
Echinococcus granulosus phd:f box containing protein 0.0016 0.0009 0.003
Echinococcus granulosus nibrin 0.006 0.0102 0.0339
Trypanosoma brucei DNA polymerase IV, putative 0.0161 0.0317 0.1121
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0044 0.0149
Onchocerca volvulus 0.0018 0.0014 0.012
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0176 0.0349 0.303
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0085 0.0083
Echinococcus multilocularis roundabout 2 0.0059 0.01 0.0115
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0021 0.0068
Trypanosoma brucei unspecified product 0.0074 0.0132 0.0464
Mycobacterium ulcerans carboxylesterase, LipT 0.0033 0.0046 0.0044
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0078
Schistosoma mansoni zinc finger protein 0.0024 0.0025 0.0084
Trypanosoma brucei histone deacetylase, putative 0.1334 0.2815 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0431 0.0893 0.3172
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0031 0.0105
Brugia malayi nuclear receptor RXR 0.0027 0.0031 0.0111
Loa Loa (eye worm) DR-78 0.0024 0.0025 0.009
Onchocerca volvulus 0.0018 0.0014 0.012
Onchocerca volvulus 0.0033 0.0046 0.0398
Echinococcus multilocularis cyclin dependent kinase 0.0048 0.0076 0.0088
Onchocerca volvulus 0.0018 0.0014 0.012
Echinococcus multilocularis muscleblind protein 1 0.0606 0.1266 0.1459
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0082 0.0274
Echinococcus granulosus histone deacetylase 0.1334 0.2815 0.9389
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.009
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0213 0.0753
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0076 0.0322
Trypanosoma cruzi FHA domain containing protein, putative 0.006 0.0102 0.0355
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0213 0.0753
Loa Loa (eye worm) hypothetical protein 0.0304 0.0621 0.2208
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0051 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0008 0.0006
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0785 0.1646 0.1644
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.006 0.0102 0.0355
Brugia malayi hypothetical protein 0.0018 0.0014 0.0049
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0048 0.0076 0.0253
Trypanosoma cruzi chloride channel protein, putative 0.002 0.0018 0.0058
Chlamydia trachomatis CBS domain-containing protein 0.002 0.0018 0.0016
Treponema pallidum fructose-bisphosphate aldolase 0.0424 0.0878 1
Loa Loa (eye worm) histone deacetylase 1 0.1094 0.2304 0.8187
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0129 0.0249 0.0885
Brugia malayi BRCA1-associated protein 2 containing protein 0.0025 0.0027 0.0095
Echinococcus multilocularis nibrin 0.006 0.0102 0.0117
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0161 0.0317 0.1369
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0009 0.001
Plasmodium falciparum CDGSH iron-sulfur domain-containing protein, putative 0.0015 0.0008 0.0006
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.0271 0.0956
Leishmania major histone deacetylase, putative 0.1094 0.2304 0.8186
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0022 0.0025
Echinococcus granulosus importin subunit beta 1 0.003 0.0038 0.0125
Echinococcus granulosus histone deacetylase 1 0.1094 0.2304 0.7687
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0021 0.002 0.0066
Echinococcus granulosus neuroligin 0.0033 0.0046 0.0153
Entamoeba histolytica Ran family GTPase 0.0022 0.0021 0.0022
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.002 0.0018 0.0064
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0213 0.0863
Leishmania major chloride channel protein, putative 0.002 0.0018 0.0058
Brugia malayi Fli-1 protein 0.0226 0.0456 0.162
Loa Loa (eye worm) hypothetical protein 0.03 0.0613 0.2177
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0021 0.0019
Brugia malayi histone deacetylase 1 (HD1) 0.1094 0.2304 0.8187
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0025 0.0027 0.0089
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0162
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.006 0.0102 0.01
Brugia malayi hypothetical protein 0.0124 0.024 0.0851
Trypanosoma brucei cdc2-related kinase 3 0.0048 0.0076 0.0264
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.0082 0.0714
Treponema pallidum DNA ligase (lig) 0.006 0.0102 0.1141
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Echinococcus granulosus geminin 0.0347 0.0714 0.2383
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0051 0.0082 0.0275
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0213 0.092
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.006 0.0059
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0082 0.0274
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0042 0.0064 0.0062
Loa Loa (eye worm) hypothetical protein 0.0038 0.0055 0.0196
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0028 0.0033 0.0112
Trichomonas vaginalis histone deacetylase, putative 0.1094 0.2304 1
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.0213 0.0246
Schistosoma mansoni hypothetical protein 0.0095 0.0177 0.0589
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0016 0.0062
Echinococcus granulosus bloom syndrome protein 0.002 0.0018 0.006
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0025 0.0084
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0006
Toxoplasma gondii histone deacetylase HDAC1 0.1334 0.2815 0.2813
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.002 0.0018 0.0058
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0002 0.0006
Toxoplasma gondii propionate-CoA ligase 0.0042 0.0064 0.0062
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.011 0.0209 0.09
Toxoplasma gondii ATPase, AAA family protein 0.006 0.0102 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0077 0.0256
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0018 0.006
Entamoeba histolytica acyl-CoA synthetase, putative 0.0143 0.0279 0.1148
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0025 0.0084
Trypanosoma brucei GMP reductase 0.002 0.0018 0.0058
Loa Loa (eye worm) hypothetical protein 0.0032 0.0043 0.0152
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.0292
Chlamydia trachomatis Mg++ transporter 0.002 0.0018 0.0016
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0304 0.0621 0.2646
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.0033 0.0137
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0332 0.1433
Brugia malayi chloride channel protein 7 0.002 0.0018 0.0064
Loa Loa (eye worm) hypothetical protein 0.0124 0.024 0.0851
Entamoeba histolytica acyl-CoA synthetase, putative 0.0143 0.0279 0.1148
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0025 0.0027 0.0095
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0043 0.0143
Brugia malayi Pax transcription activation domain interacting protein 0.006 0.0102 0.0361
Plasmodium vivax flap endonuclease 1, putative 0.0052 0.0085 0.0084
Echinococcus multilocularis geminin 0.0347 0.0714 0.0824
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0022 0.0078
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.002 0.0018 0.0033
Mycobacterium ulcerans hypothetical protein 0.0155 0.0304 0.0303
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0016 0.0056
Toxoplasma gondii ImpB/MucB/SamB family protein 0.006 0.0102 0.01
Loa Loa (eye worm) phosphofructokinase 0.0112 0.0213 0.0758
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0021 0.002 0.0019
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0085 0.0083
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0021 0.002 0.0066
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0032
Echinococcus granulosus serine:threonine kinase SAD 1 0.0048 0.0077 0.0256
Echinococcus multilocularis cpg binding protein 0.0062 0.0107 0.0124
Brugia malayi AMP-binding enzyme family protein 0.0143 0.0279 0.099
Brugia malayi Protein kinase domain containing protein 0.0048 0.0076 0.027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.009
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0016 0.005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0051 0.0082 0.0081
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0025 0.009
Echinococcus granulosus carboxylesterase 5A 0.0198 0.0396 0.1321
Trypanosoma brucei DNA polymerase IV, putative 0.0148 0.0289 0.102
Loa Loa (eye worm) hypothetical protein 0.0198 0.0396 0.1408
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0162
Loa Loa (eye worm) hypothetical protein 0.006 0.0102 0.0361
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0082 0.0095
Mycobacterium ulcerans acyl-CoA synthetase 0.0042 0.0064 0.0062
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0016 0.0014
Loa Loa (eye worm) glutaminase 0.0563 0.1174 0.4171
Leishmania major 4-coumarate:coa ligase-like protein 0.0143 0.0279 0.0985
Toxoplasma gondii glycogen synthase, putative 0.0014 0.0004 0.0003
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.002 0.0018 0.0058
Schistosoma mansoni acetyl-CoA synthetase 0.0042 0.0064 0.0213
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0162
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0042 0.0064 0.0126
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0028 0.0033 0.0118
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.0133 0.0153
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Schistosoma mansoni DNA helicase recq1 0.002 0.0018 0.006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.0082 0.0292
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0031 0.0036
Onchocerca volvulus 0.0066 0.0115 0.1001
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.1094 0.2304 1
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0042 0.0064 0.0074
Mycobacterium tuberculosis Conserved protein 0.002 0.0018 0.0033
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0003 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.016 0.0564
Brugia malayi Prion-like- 0.0022 0.0022 0.0078
Loa Loa (eye worm) patched family protein 0.0018 0.0014 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0161 0.0317 0.1121
Toxoplasma gondii NEK kinase 0.0021 0.002 0.0019
Toxoplasma gondii patched family protein 0.0018 0.0014 0.0012
Trypanosoma cruzi DNA damage repair protein, putative 0.0033 0.0046 0.0156
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0068 0.0067
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0078
Toxoplasma gondii NEK kinase 0.0021 0.002 0.0019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0424 0.0878 0.3805
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0025 0.009
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.002 0.0018 0.0016
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0016 0.0029
Loa Loa (eye worm) AUR protein kinase 0.0168 0.0332 0.1178
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0184 0.0366 0.0422
Leishmania major hypothetical protein, conserved 0.0025 0.0027 0.0089
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.0213 0.0712
Brugia malayi Niemann-Pick C1 protein precursor 0.0304 0.0621 0.2208
Echinococcus multilocularis histone deacetylase 6 0.1358 0.2867 0.3306
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0044 0.0121
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0039 0.0427
Schistosoma mansoni protein kinase subunit gamma 0.0227 0.0457 0.1526
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0028 0.0033 0.0111
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0085 0.0157 0.0181
Schistosoma mansoni alkaline phosphatase 0.0168 0.0332 0.1107
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0009 0.001
Echinococcus multilocularis conserved hypothetical protein 0.0015 0.0008 0.0009
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0168 0.0332 0.138
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.0292
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Loa Loa (eye worm) hypothetical protein 0.0205 0.0411 0.146
Brugia malayi TAR-binding protein 0.0129 0.0249 0.0885
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0009 0.003
Treponema pallidum P26 0.0014 0.0004 0.0029
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0042 0.0064 0.0126
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0003 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0006
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0033 0.0112
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0025 0.009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0111
Echinococcus multilocularis dna polymerase kappa 0.0161 0.0317 0.0365
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0213 0.0863
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0104 0.012
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0346 0.1493
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0055 0.0064
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0785 0.1646 0.3344
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0028 0.0033 0.0111
Onchocerca volvulus 0.0246 0.0498 0.4328
Schistosoma mansoni protein kinase 0.0168 0.0332 0.1106
Echinococcus granulosus roundabout 2 0.0059 0.01 0.0333
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0053 0.0051
Brugia malayi Patched family protein 0.0018 0.0014 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0077 0.0256
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0017 0.001 0.0012
Entamoeba histolytica serine/threonine protein kinase, putative 0.0021 0.002 0.0019
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0121 0.0231 0.0817
Plasmodium vivax DNA repair protein REV1, putative 0.0033 0.0046 0.0044
Trypanosoma brucei histone deacetylase 1 0.1094 0.2304 0.8186
Echinococcus multilocularis importin subunit beta 1 0.003 0.0038 0.0043
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0025 0.0029
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.009
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0055 0.0233
Loa Loa (eye worm) hypothetical protein 0.0134 0.0259 0.0921
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0102 0.0434
Schistosoma mansoni neuroligin 3 (S09 family) 0.0033 0.0046 0.0153
Loa Loa (eye worm) hypothetical protein 0.0552 0.115 0.4087
Schistosoma mansoni vesicular amine transporter 0.0036 0.0052 0.0174
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0031 0.0111
Brugia malayi intracellular kinase 0.0051 0.0082 0.0292
Trypanosoma cruzi DNA polymerase kappa, putative 0.0161 0.0317 0.1121
Echinococcus granulosus Niemann Pick C1 protein 0.0304 0.0621 0.2073
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0038 0.0126
Trypanosoma brucei DNA polymerase kappa, putative 0.0161 0.0317 0.1121
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0009 0.003
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0076 0.0253
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0016 0.0162
Echinococcus granulosus tar DNA binding protein 0.0129 0.0249 0.0831
Brugia malayi cell division control protein 2 homolog 0.0048 0.0076 0.027
Mycobacterium tuberculosis Probable dehydrogenase 0.0084 0.0153 0.0308
Brugia malayi CHE-14 protein 0.013 0.0252 0.0896
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0025 0.0029
Plasmodium falciparum histone deacetylase 2 0.1334 0.2815 0.2813
Entamoeba histolytica protein kinase, putative 0.0168 0.0332 0.138
Echinococcus granulosus Niemann Pick C1 protein 0.0434 0.0899 0.2999
Trypanosoma brucei DNA polymerase kappa, putative 0.0161 0.0317 0.1121
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.0082 0.0292
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0045 0.0161
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0309 0.0631 0.2106
Schistosoma mansoni brca1-associated protein (brap2) 0.0025 0.0027 0.0089
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.0133 0.0444
Giardia lamblia Histone deacetylase 0.1094 0.2304 1
Brugia malayi steroid hormone receptor 0.0051 0.0082 0.0292
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0038 0.0127
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Onchocerca volvulus 0.0033 0.0046 0.0398
Plasmodium falciparum chorismate synthase 0.4709 1 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0115 0.0409
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0424 0.0878 0.3805
Toxoplasma gondii patched family protein 0.0018 0.0014 0.0012
Loa Loa (eye worm) patched family protein 0.0018 0.0014 0.0049
Toxoplasma gondii CBS domain-containing protein 0.002 0.0018 0.0016
Echinococcus multilocularis Immunoglobulin 0.0036 0.0052 0.006
Loa Loa (eye worm) hypothetical protein 0.0606 0.1266 0.4497
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.0082 0.0274
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0028 0.0033 0.0032
Loa Loa (eye worm) hypothetical protein 0.0059 0.01 0.0354
Echinococcus multilocularis histone deacetylase 8 0.0552 0.115 0.1327
Loa Loa (eye worm) hypothetical protein 0.0072 0.0127 0.0453
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0002 0.0002
Plasmodium falciparum NIMA related kinase 4 0.0021 0.002 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Loa Loa (eye worm) hypothetical protein 0.0066 0.0115 0.0409
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0249 0.0831
Toxoplasma gondii CBS domain-containing protein 0.002 0.0018 0.0016
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.0033 0.0137
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.0304 0.0615
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0077 0.0326
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.002 0.0018 0.0058
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0107 0.0202 0.02
Trypanosoma cruzi DNA polymerase eta, putative 0.0134 0.0259 0.0916
Loa Loa (eye worm) patched family protein 0.0018 0.0014 0.0049
Loa Loa (eye worm) hypothetical protein 0.0036 0.0052 0.0186
Schistosoma mansoni gliotactin 0.0033 0.0046 0.0153
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0066 0.0115 0.0384
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.0082 0.0274
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0002 0.0006
Onchocerca volvulus 0.0051 0.0082 0.0714
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0051 0.0214
Leishmania major DNA polymerase kappa, putative 0.0033 0.0046 0.0156
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.006 0.0102 0.0434
Schistosoma mansoni cpg binding protein 0.0059 0.01 0.0334
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.001 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0009 0.0032
Leishmania major DNA polymerase eta, putative 0.006 0.0102 0.0355
Leishmania major hypothetical protein, conserved 0.002 0.0018 0.0058
Brugia malayi Carboxylesterase family protein 0.0198 0.0396 0.1408
Loa Loa (eye worm) hypothetical protein 0.0806 0.1691 0.6008
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0021 0.0074
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0042 0.0064 0.0221
Trypanosoma cruzi histone deacetylase, putative 0.0552 0.115 0.4084
Trypanosoma brucei DNA polymerase kappa, putative 0.0161 0.0317 0.1121
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0046 0.0156
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0082 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.0161 0.0317 0.1121
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0111 0.037
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0235 0.0474 0.1685
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.0022 0.0078
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0016 0.005
Entamoeba histolytica protein kinase, putative 0.0051 0.0082 0.029
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0051 0.0175
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.011 0.0209 0.0743
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0055 0.019
Echinococcus granulosus cyclin dependent kinase 1 0.0048 0.0076 0.0253
Loa Loa (eye worm) hypothetical protein 0.0033 0.0046 0.0163
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0184 0.0366 0.122
Echinococcus multilocularis tumor protein p63 0.0682 0.1427 0.1645
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0025 0.0027 0.0025
Loa Loa (eye worm) patched family protein 0.0018 0.0014 0.0049
Entamoeba histolytica histone deacetylase, putative 0.1094 0.2304 1
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.002 0.0018 0.006
Schistosoma mansoni histone deacetylase 4 5 0.1334 0.2815 0.9389
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0042 0.0064 0.0093
Schistosoma mansoni hypothetical protein 0.0095 0.0177 0.0589
Brugia malayi amine oxidase, flavin-containing family protein 0.0066 0.0115 0.0409

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 100 uM In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactor ChEMBL. 1573633
IC50 (functional) > 100 uM Compound was evaluated for inhibition of [3H]-methotrexate uptake into MOLT-4 cells ChEMBL. 1573633
IC50 (functional) > 100 uM Compound was evaluated in vitro for inhibition of growth of MCF-7 human breast adenocarcinoma using 72 hours continuous exposure ChEMBL. 1573633
IC50 (binding) > 100 uM In vitro inhibition of hog liver GAR transformylase with (6R)-10-formyl-FH4 as cofactor ChEMBL. 1573633
IC50 (functional) > 100 uM Compound was evaluated for inhibition of [3H]-methotrexate uptake into MOLT-4 cells ChEMBL. 1573633
IC50 (functional) > 100 uM Compound was evaluated in vitro for inhibition of growth of MCF-7 human breast adenocarcinoma using 72 hours continuous exposure ChEMBL. 1573633

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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