Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0038 | 0.0113 | 0.0113 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0164 | 0.0164 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0279 | 0.0279 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.0279 | 0.0403 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0589 | 0.0851 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0038 | 0.0113 | 0.0163 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0053 | 0.0207 | 0.0207 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0053 | 0.0207 | 0.0299 |
Schistosoma mansoni | thyroid hormone receptor | 0.0112 | 0.0589 | 0.0589 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0038 | 0.0113 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0589 | 0.0851 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0064 | 0.0279 | 0.0403 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.01 | 0.01 |
Leishmania major | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0112 | 0.0589 | 0.0613 |
Brugia malayi | RNA binding protein | 0.0064 | 0.0279 | 0.0403 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0112 | 0.0589 | 0.0589 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0589 | 0.0851 |
Brugia malayi | nuclear hormone receptor | 0.0112 | 0.0589 | 0.0851 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0038 | 0.0113 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0248 | 0.0358 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0053 | 0.0207 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0589 | 0.0851 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.1106 | 0.1597 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0164 | 0.0164 |
Trypanosoma brucei | unspecified product | 0.0026 | 0.0036 | 0.0009 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0038 | 0.0113 | 0.012 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0038 | 0.0113 | 0.0163 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.01 | 0.0145 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0112 | 0.0589 | 0.0851 |
Schistosoma mansoni | nuclear receptor | 0.0053 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0112 | 0.0589 | 0.0851 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0026 | 0.0036 | 0.0037 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0053 | 0.0207 | 0.0299 |
Brugia malayi | steroid hormone receptor | 0.0112 | 0.0589 | 0.0851 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0038 | 0.0113 | 0.0113 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0164 | 0.0164 |
Schistosoma mansoni | nuclear receptor | 0.0053 | 0.0207 | 0.0207 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0164 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0248 | 0.0358 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0053 | 0.0207 | 0.0207 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0248 | 0.0358 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0112 | 0.0589 | 0.5328 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0112 | 0.0589 | 0.0589 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0589 | 0.0851 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0026 | 0.0036 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.0279 | 0.0403 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0112 | 0.0589 | 0.0613 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0053 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0589 | 0.0851 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0112 | 0.0589 | 0.0851 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.0036 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0112 | 0.0589 | 0.0589 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Onchocerca volvulus | 0.0112 | 0.0589 | 0.5328 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0164 | 0.0171 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.1568 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Brugia malayi | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0064 | 0.0279 | 0.0361 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0036 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0248 | 0.0358 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0038 | 0.0113 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.0279 | 0.0279 |
Brugia malayi | ecdysone receptor | 0.0053 | 0.0207 | 0.0299 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0112 | 0.0589 | 0.0851 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0053 | 0.0207 | 0.0207 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0112 | 0.0589 | 0.0851 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0112 | 0.0589 | 0.0589 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0059 | 0.0248 | 0.0358 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0059 | 0.0248 | 0.0248 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0038 | 0.0113 | 0.012 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0036 | 0.0009 |
Brugia malayi | nuclear hormone receptor | 0.0053 | 0.0207 | 0.0299 |
Echinococcus granulosus | FTZ F1 alpha | 0.0112 | 0.0589 | 0.0589 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0112 | 0.0589 | 0.0851 |
Brugia malayi | tailless protein | 0.0053 | 0.0207 | 0.0299 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0112 | 0.0589 | 0.0613 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0053 | 0.0207 | 0.0215 |
Schistosoma mansoni | zinc finger protein | 0.0053 | 0.0207 | 0.0207 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0112 | 0.0589 | 0.0589 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0112 | 0.0589 | 0.0613 |
Echinococcus granulosus | geminin | 0.0171 | 0.0971 | 0.0971 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0112 | 0.0589 | 0.0589 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0053 | 0.0207 | 0.0207 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.01 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Brugia malayi | nuclear receptor RXR | 0.0053 | 0.0207 | 0.0299 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0038 | 0.0113 | 0.0163 |
Onchocerca volvulus | 0.0053 | 0.0207 | 0.1872 | |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0279 | 0.0403 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0053 | 0.0207 | 0.0299 |
Schistosoma mansoni | nuclear hormone receptor | 0.0053 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0164 | 0.0237 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0112 | 0.0589 | 0.0851 |
Schistosoma mansoni | flap endonuclease-1 | 0.0024 | 0.0019 | 0.0019 |
Echinococcus granulosus | dna polymerase kappa | 0.0038 | 0.0113 | 0.0113 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0279 | 0.0279 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0059 | 0.0248 | 0.0358 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0038 | 0.0113 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0279 | 0.0279 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0038 | 0.0113 | 0.0113 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.1092 | 0.6927 | 1 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.1092 | 0.6927 | 1 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0053 | 0.0207 | 0.0207 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0053 | 0.0207 | 0.0215 |
Brugia malayi | Flap endonuclease-1 | 0.0026 | 0.0036 | 0.0051 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0112 | 0.0589 | 0.0589 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.01 | 0.0145 |
Brugia malayi | ecdysteroid receptor | 0.0112 | 0.0589 | 0.0851 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0053 | 0.0207 | 0.1872 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Leishmania major | DNA polymerase eta, putative | 0.0064 | 0.0279 | 0.0361 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0112 | 0.0589 | 0.0589 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.0971 | 0.0971 |
Brugia malayi | hypothetical protein | 0.0059 | 0.0248 | 0.0358 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0059 | 0.0248 | 0.0358 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0026 | 0.0036 | 0.0051 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0038 | 0.0109 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0053 | 0.0207 | 0.0299 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0164 | 0.0164 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0279 | 0.0279 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0112 | 0.0589 | 0.0851 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0112 | 0.0589 | 0.0851 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.1509 | 0.9618 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0164 | 0.0164 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0059 | 0.0248 | 0.0258 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0112 | 0.0589 | 0.0851 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0038 | 0.0113 | 0.012 |
Brugia malayi | nuclear receptor NHR-88 | 0.0053 | 0.0207 | 0.0299 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0053 | 0.0207 | 0.0207 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0112 | 0.0589 | 0.0851 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0053 | 0.0207 | 0.0299 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0112 | 0.0589 | 0.0613 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0112 | 0.0589 | 0.0851 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0064 | 0.0279 | 0.0361 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0248 | 0.0358 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0112 | 0.0589 | 0.0851 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0053 | 0.0207 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.0036 | 0.0008 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0112 | 0.0589 | 0.0589 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0038 | 0.0113 | 0.5 |
Brugia malayi | nuclear receptor RXR | 0.0059 | 0.0248 | 0.0358 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0053 | 0.0207 | 0.0299 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0112 | 0.0589 | 0.0589 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0038 | 0.0113 | 0.0117 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Schistosoma mansoni | coup transcription factor | 0.0112 | 0.0589 | 0.0589 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.1092 | 0.6927 | 0.6927 |
Brugia malayi | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0036 | 0.0009 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0053 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.0279 | 0.0403 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0053 | 0.0207 | 0.0215 |
Schistosoma mansoni | nuclear hormone receptor | 0.0053 | 0.0207 | 0.0207 |
Giardia lamblia | DINP protein human, muc B family | 0.0038 | 0.0113 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0589 | 0.0851 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0053 | 0.0207 | 0.0207 |
Trypanosoma brucei | unspecified product | 0.0026 | 0.0036 | 0.0009 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0112 | 0.0589 | 0.5328 |
Loa Loa (eye worm) | DR-78 | 0.0053 | 0.0207 | 0.0299 |
Onchocerca volvulus | 0.0192 | 0.1106 | 1 | |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0026 | 0.0036 | 0.0694 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.1106 | 0.1597 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0112 | 0.0589 | 0.0851 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0279 | 0.0279 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0112 | 0.0589 | 0.5328 |
Schistosoma mansoni | DNA polymerase eta | 0.0064 | 0.0279 | 0.0279 |
Echinococcus granulosus | dna polymerase eta | 0.0064 | 0.0279 | 0.0279 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.0279 | 0.0403 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0112 | 0.0589 | 0.0851 |
Brugia malayi | hypothetical protein | 0.0059 | 0.0248 | 0.0358 |
Schistosoma mansoni | thyroid hormone receptor | 0.0112 | 0.0589 | 0.0589 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.1092 | 0.6927 | 1 |
Trypanosoma brucei | unspecified product | 0.0038 | 0.0113 | 0.012 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.1092 | 0.6927 | 0.6927 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0632 | 0.3953 | 0.411 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0059 | 0.0248 | 0.0248 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0112 | 0.0589 | 0.0851 |
Brugia malayi | hypothetical protein | 0.0192 | 0.1106 | 0.1597 |
Brugia malayi | hypothetical protein | 0.0036 | 0.01 | 0.0145 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0112 | 0.0589 | 0.0851 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.1092 | 0.6927 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0112 | 0.0589 | 0.0589 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0112 | 0.0589 | 0.0851 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.1092 | 0.6927 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0589 | 0.0851 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.01 | 0.01 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0112 | 0.0589 | 0.0613 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0112 | 0.0589 | 0.0851 |
Schistosoma mansoni | nuclear hormone receptor | 0.0112 | 0.0589 | 0.0589 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0059 | 0.0248 | 0.0248 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.01 | 0.01 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0112 | 0.0589 | 0.0851 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0038 | 0.0113 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0112 | 0.0589 | 0.0589 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.0036 | 0.0008 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0632 | 0.3953 | 0.3953 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0112 | 0.0589 | 0.0613 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0053 | 0.0207 | 0.0215 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0112 | 0.0589 | 0.0589 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0053 | 0.0207 | 0.1872 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0038 | 0.0113 | 0.012 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.0971 | 0.0971 |
Brugia malayi | conserved hypotetical protein | 0.0053 | 0.0207 | 0.0299 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0053 | 0.0207 | 0.0299 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0112 | 0.0589 | 0.0613 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.01 | 0.0145 |
Echinococcus multilocularis | dna polymerase eta | 0.0064 | 0.0279 | 0.029 |
Echinococcus multilocularis | dna polymerase kappa | 0.0038 | 0.0113 | 0.0117 |
Leishmania major | DNA polymerase eta, putative | 0.0038 | 0.0109 | 0.0114 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.1092 | 0.6927 | 0.7202 |
Plasmodium falciparum | flap endonuclease 1 | 0.0026 | 0.0036 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.1092 | 0.6927 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0112 | 0.0589 | 0.0851 |
Brugia malayi | hypothetical protein | 0.0025 | 0.003 | 0.0044 |
Brugia malayi | nuclear receptor NHR-88 | 0.0112 | 0.0589 | 0.0851 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.1092 | 0.6927 | 1 |
Onchocerca volvulus | 0.0053 | 0.0207 | 0.1872 | |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0164 | 0.0237 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.0279 | 0.0403 |
Entamoeba histolytica | Flap nuclease, putative | 0.0026 | 0.0036 | 0.0051 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0112 | 0.0589 | 0.0851 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.01 | 0.0145 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0112 | 0.0589 | 0.0589 |
Echinococcus multilocularis | geminin | 0.0171 | 0.0971 | 0.1009 |
Echinococcus granulosus | flap endonuclease 1 | 0.0026 | 0.0036 | 0.0036 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0112 | 0.0589 | 0.0613 |
Brugia malayi | nuclear receptor NHR-67 | 0.0053 | 0.0207 | 0.0299 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0112 | 0.0589 | 0.0589 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0053 | 0.0207 | 0.0299 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0113 | 0.012 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0112 | 0.0589 | 0.0851 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.003 | 0.0044 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.0279 | 0.029 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0207 | 0.0299 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0038 | 0.0109 | 0.0114 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0112 | 0.0589 | 0.0851 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 1000 nM | Inhibition of human CYP24 hydroxylase expressed in V79 cells | ChEMBL. | 15615534 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.