Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0047 | 1 | 1 |
Brugia malayi | larval opioid receptor | 0.0047 | 1 | 1 |
Echinococcus multilocularis | allatostatin A receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0047 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0047 | 1 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0022 | 0.3789 | 0.5 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0037 | 0.7459 | 0.7459 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0022 | 0.3789 | 0.5 |
Leishmania major | cytochrome p450-like protein | 0.0022 | 0.3789 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0022 | 0.3789 | 0.5 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 1 | 1 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0047 | 1 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0037 | 0.7459 | 0.7459 |
Schistosoma mansoni | histamine h1 receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0047 | 1 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0047 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0047 | 1 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0047 | 1 | 1 |
Brugia malayi | AKH receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0047 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0022 | 0.3789 | 0.3789 |
Brugia malayi | sulfakinin receptor protein | 0.0047 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0047 | 1 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0022 | 0.3789 | 0.5 |
Brugia malayi | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0047 | 1 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0022 | 0.3789 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0047 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0047 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0022 | 0.3789 | 0.5 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0022 | 0.3789 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0047 | 1 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0047 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0022 | 0.3789 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0022 | 0.3789 | 0.5 |
Brugia malayi | hypothetical protein | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0022 | 0.3789 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0047 | 1 | 1 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0047 | 1 | 0.5 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0022 | 0.3789 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0047 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.6231 | 0.6231 |
Brugia malayi | neuropeptide F receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0022 | 0.3789 | 0.5 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0011 | 0.0854 | 0.0854 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0047 | 1 | 0.5 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0047 | 1 | 1 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0022 | 0.3789 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0047 | 1 | 1 |
Echinococcus multilocularis | 0.0022 | 0.3789 | 0.3789 | |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0034 | 0.6847 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0022 | 0.3789 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0011 | 0.0854 | 0.0854 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Brugia malayi | G protein-coupled receptor | 0.0047 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0047 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0022 | 0.3789 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0022 | 0.3789 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0022 | 0.3789 | 0.5 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0022 | 0.3789 | 0.5 |
Echinococcus multilocularis | somatostatin receptor | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0022 | 0.3789 | 0.5 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0011 | 0.0854 | 0.0854 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0047 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.004 | 0.8314 | 0.8314 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0047 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0047 | 1 | 1 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0047 | 1 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | g-protein coupled receptor | 0.0047 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0022 | 0.3789 | 0.5 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Brugia malayi | Serotonin receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Schistosoma mansoni | opsin-like receptor | 0.0047 | 1 | 1 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0011 | 0.0854 | 0.0854 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0047 | 1 | 1 |
Mycobacterium leprae | putative cytochrome p450 | 0.0022 | 0.3789 | 0.5 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0022 | 0.3789 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0047 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0022 | 0.3789 | 0.5 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0022 | 0.3789 | 0.3789 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0022 | 0.3789 | 0.5 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0047 | 1 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.0047 | 1 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0047 | 1 | 1 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0047 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0047 | 1 | 1 |
Echinococcus granulosus | sex peptide receptor | 0.0047 | 1 | 1 |
Brugia malayi | Serotonin receptor | 0.0047 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0022 | 0.3789 | 0.5 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Echinococcus granulosus | fmrfamide receptor | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0022 | 0.3789 | 0.5 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0047 | 1 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0047 | 1 | 1 |
Brugia malayi | GnHR receptor homolog | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | serotonin receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0047 | 1 | 1 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0047 | 1 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0047 | 1 | 1 |
Brugia malayi | Dopamine receptor protein 1 | 0.0047 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0047 | 1 | 1 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0022 | 0.3789 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Brugia malayi | cytochrome P450 | 0.0022 | 0.3789 | 0.3789 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0047 | 1 | 1 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0047 | 1 | 1 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0022 | 0.3789 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0047 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0011 | 0.0854 | 0.0854 |
Echinococcus granulosus | orexin receptor type 2 | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0022 | 0.3789 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0022 | 0.3789 | 0.3789 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.3789 | 0.3789 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0047 | 1 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0047 | 1 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0022 | 0.3789 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0022 | 0.3789 | 0.5 |
Brugia malayi | hypothetical protein | 0.0047 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0022 | 0.3789 | 0.5 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 | 0.0022 | 0.3789 | 0.3789 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0047 | 1 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.0047 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0034 | 0.6847 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0022 | 0.3789 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.004 | 0.8314 | 0.8314 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Echinococcus multilocularis | orexin receptor type 2 | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0037 | 0.7459 | 0.7459 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0047 | 1 | 1 |
Brugia malayi | Dopamine receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus granulosus | voltage gated potassium channel | 0.0011 | 0.0854 | 0.0854 |
Schistosoma mansoni | adenoreceptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.3789 | 0.3789 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0047 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0037 | 0.7459 | 0.7459 |
Brugia malayi | RE15519p | 0.0047 | 1 | 1 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0047 | 1 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0047 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.3789 | 0.3789 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0022 | 0.3789 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0047 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0047 | 1 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0022 | 0.3789 | 0.5 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0022 | 0.3789 | 0.5 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0047 | 1 | 1 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0022 | 0.3789 | 0.5 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | somatostatin receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0047 | 1 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0047 | 1 | 1 |
Brugia malayi | Melatonin receptor type 1A | 0.0047 | 1 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0022 | 0.3789 | 0.5 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.3789 | 0.3789 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Echinococcus multilocularis | sex peptide receptor | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0022 | 0.3789 | 0.5 |
Schistosoma mansoni | myosin xvIII | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0047 | 1 | 1 |
Schistosoma mansoni | cytochrome P450 | 0.0022 | 0.3789 | 0.3789 |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.3789 | 0.3789 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0022 | 0.3789 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0022 | 0.3789 | 0.3789 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0022 | 0.3789 | 0.3789 |
Brugia malayi | Dopamine receptor protein 2 | 0.0047 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0047 | 1 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0011 | 0.0854 | 0.0854 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0022 | 0.3789 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0047 | 1 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0047 | 1 | 1 |
Echinococcus granulosus | allatostatin A receptor | 0.0047 | 1 | 1 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0022 | 0.3789 | 0.5 |
Echinococcus granulosus | g protein coupled receptor | 0.0047 | 1 | 1 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0047 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0022 | 0.3789 | 0.5 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0047 | 1 | 1 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0047 | 1 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0022 | 0.3789 | 0.5 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0047 | 1 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0022 | 0.3789 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0047 | 1 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0047 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0047 | 1 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0022 | 0.3789 | 0.5 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0047 | 1 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0022 | 0.3789 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0047 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0022 | 0.3789 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0022 | 0.3789 | 0.5 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0047 | 1 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Leishmania major | cytochrome p450-like protein | 0.0022 | 0.3789 | 0.5 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0022 | 0.3789 | 0.5 |
Onchocerca volvulus | 0.0047 | 1 | 0.5 | |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0047 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0022 | 0.3789 | 0.5 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0047 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0022 | 0.3789 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0854 | 0.0854 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0022 | 0.3789 | 0.5 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0047 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | 0 | Inhibition of HIV1 RT K103N mutant | ChEMBL. | 16279773 |
IC50 (binding) | 0 | Inhibition of HIV1 RT V106A mutant | ChEMBL. | 16279773 |
IC50 (binding) | 0 | Inhibition of HIV1 RT Y181I mutant | ChEMBL. | 16279773 |
IC50 (binding) | 0 | Inhibition of HIV1 RT Y188L mutant | ChEMBL. | 16279773 |
IC50 (binding) | 0 | Inhibition of HIV1 RT L100I mutant | ChEMBL. | 16279773 |
Inhibition (binding) | <= 10 % | Inhibition of HIV1 RT at 100 uM | ChEMBL. | 16279773 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.