Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.2756 | 0.2756 |
Brugia malayi | follicle stimulating hormone receptor | 0.0034 | 0.693 | 0.7724 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0019 | 0.2756 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.2756 | 0.3071 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0019 | 0.2756 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0012 | 0.1028 | 0.1145 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.2756 | 0.3071 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | opsin-like receptor | 0.0034 | 0.693 | 0.693 |
Schistosoma mansoni | amine GPCR | 0.0034 | 0.693 | 0.693 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0034 | 0.693 | 0.7724 |
Mycobacterium leprae | putative cytochrome p450 | 0.0019 | 0.2756 | 0.5 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0034 | 0.693 | 0.693 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | cytochrome P450 | 0.0019 | 0.2756 | 0.2756 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0034 | 0.693 | 0.7724 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0019 | 0.2756 | 0.5 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0034 | 0.693 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0042 | 0.8972 | 1 |
Brugia malayi | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.2756 | 0.3071 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0034 | 0.693 | 0.693 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0034 | 0.693 | 0.693 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0034 | 0.693 | 0.7724 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0034 | 0.693 | 0.7724 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0019 | 0.2756 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0019 | 0.2756 | 0.5 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0019 | 0.2756 | 0.5 |
Brugia malayi | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1028 | 0.1145 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0034 | 0.693 | 0.693 |
Brugia malayi | cytochrome P450 | 0.0019 | 0.2756 | 0.3071 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0034 | 0.693 | 0.7724 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0019 | 0.2756 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0034 | 0.693 | 0.693 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Schistosoma mansoni | biogenic amine receptor | 0.0034 | 0.693 | 0.693 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0019 | 0.2756 | 0.5 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | orexin receptor type 2 | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | serotonin receptor | 0.0034 | 0.693 | 0.7724 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0019 | 0.2756 | 0.5 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0019 | 0.2756 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0034 | 0.693 | 0.693 |
Brugia malayi | neuropeptide F receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0019 | 0.2756 | 0.5 |
Brugia malayi | putative neuropeptide receptor | 0.0034 | 0.693 | 0.7724 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.2756 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0019 | 0.2756 | 0.5 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0034 | 0.693 | 0.693 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.7495 | 0.8354 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | neuropeptide receptor | 0.0034 | 0.693 | 0.693 |
Brugia malayi | G-protein coupled receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.693 | 0.693 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0034 | 0.693 | 0.7724 |
Leishmania major | cytochrome p450-like protein | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 | 0.0019 | 0.2756 | 0.3071 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0034 | 0.693 | 0.693 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0034 | 0.693 | 0.693 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.2756 | 0.3071 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | adenoreceptor | 0.0034 | 0.693 | 0.693 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.2756 | 0.3071 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0034 | 0.693 | 0.7724 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0034 | 0.693 | 0.693 |
Echinococcus multilocularis | sex peptide receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0042 | 0.8972 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0012 | 0.1028 | 0.1145 |
Echinococcus granulosus | somatostatin receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | allatostatin A receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0042 | 0.8972 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0034 | 0.693 | 0.693 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0019 | 0.2756 | 0.5 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | neuropeptide F receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | neuropeptide s receptor | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.693 | 0.693 |
Schistosoma mansoni | neuropeptide receptor | 0.0034 | 0.693 | 0.693 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Brugia malayi | G protein-coupled receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0034 | 0.693 | 0.693 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Leishmania major | cytochrome p450-like protein | 0.0019 | 0.2756 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0034 | 0.693 | 0.693 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | somatostatin receptor | 0.0034 | 0.693 | 0.7724 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0019 | 0.2756 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.693 | 0.693 |
Brugia malayi | larval opioid receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0034 | 0.693 | 0.693 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0034 | 0.693 | 0.7724 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0019 | 0.2756 | 0.5 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Brugia malayi | G-protein coupled receptor | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | voltage gated potassium channel | 0.0012 | 0.1028 | 0.1145 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0039 | 0.8236 | 1 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | g protein coupled receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | sex peptide receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | g protein coupled receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | neuropeptide receptor | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | opsin-like receptor | 0.0034 | 0.693 | 0.693 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0034 | 0.693 | 0.693 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0019 | 0.2756 | 0.3071 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0019 | 0.2756 | 0.5 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0012 | 0.1028 | 0.1145 |
Echinococcus granulosus | fmrfamide receptor | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | Melatonin receptor type 1A | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | neuropeptide receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | opsin-like receptor | 0.0034 | 0.693 | 0.693 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0012 | 0.1028 | 0.1028 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | RE15519p | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0034 | 0.693 | 0.693 |
Brugia malayi | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.2756 | 0.3071 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.2756 | 0.3071 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | amine GPCR | 0.0034 | 0.693 | 0.693 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.2756 | 0.5 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0012 | 0.1028 | 0.1145 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0019 | 0.2756 | 0.5 |
Trypanosoma brucei | cytochrome P450, putative | 0.0019 | 0.2756 | 0.5 |
Brugia malayi | Dopamine receptor | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0019 | 0.2756 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0019 | 0.2756 | 0.5 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0034 | 0.693 | 0.693 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0034 | 0.693 | 0.693 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0034 | 0.693 | 0.7724 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0019 | 0.2756 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0034 | 0.693 | 0.693 |
Brugia malayi | Serotonin receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | neuropeptide receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | g protein coupled receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | fmrfamide receptor | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0046 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | sulfakinin receptor protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | neuropeptide receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | 0.0019 | 0.2756 | 0.3071 | |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0019 | 0.2756 | 0.3071 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0019 | 0.2756 | 0.5 |
Echinococcus granulosus | allatostatin A receptor | 0.0034 | 0.693 | 0.7724 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0019 | 0.2756 | 0.5 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0019 | 0.2756 | 0.5 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Brugia malayi | AKH receptor | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0034 | 0.693 | 0.693 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.693 | 0.693 |
Brugia malayi | GnHR receptor homolog | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0019 | 0.2756 | 0.5 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0034 | 0.693 | 0.693 |
Echinococcus granulosus | g protein coupled receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | g-protein coupled receptor | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.693 | 0.693 |
Echinococcus multilocularis | serotonin receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.693 | 0.693 |
Schistosoma mansoni | amine GPCR | 0.0034 | 0.693 | 0.693 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.693 | 0.693 |
Brugia malayi | ORL1-like opioid receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0034 | 0.693 | 0.693 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | myosin xvIII | 0.0034 | 0.693 | 0.693 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0034 | 0.693 | 0.693 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.693 | 0.693 |
Echinococcus multilocularis | serotonin receptor | 0.0034 | 0.693 | 0.7724 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0034 | 0.693 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.693 | 0.693 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0034 | 0.693 | 0.7724 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0019 | 0.2756 | 0.5 |
Brugia malayi | Serotonin receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0019 | 0.2756 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.693 | 0.693 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0019 | 0.2756 | 0.5 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0019 | 0.2756 | 0.5 |
Brugia malayi | Dopamine receptor protein 1 | 0.0034 | 0.693 | 0.7724 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0019 | 0.2756 | 0.5 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0019 | 0.2756 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0019 | 0.2756 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0034 | 0.693 | 0.693 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0034 | 0.693 | 0.7724 |
Brugia malayi | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.693 | 0.693 |
Echinococcus multilocularis | g protein coupled receptor | 0.0034 | 0.693 | 0.7724 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0012 | 0.1028 | 0.1028 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0034 | 0.693 | 0.7724 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0019 | 0.2756 | 0.5 |
Echinococcus multilocularis | fmrfamide receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.693 | 0.693 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.693 | 0.693 |
Schistosoma mansoni | amine GPCR | 0.0034 | 0.693 | 0.693 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0034 | 0.693 | 0.693 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0019 | 0.2756 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.693 | 0.7724 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0034 | 0.693 | 0.693 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0019 | 0.2756 | 0.5 |
Brugia malayi | Dopamine receptor protein 2 | 0.0034 | 0.693 | 0.7724 |
Onchocerca volvulus | 0.0034 | 0.693 | 0.5 | |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0034 | 0.693 | 0.7724 |
Leishmania major | cytochrome p450-like protein | 0.0019 | 0.2756 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0019 | 0.2756 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.0034 | 0.693 | 0.7724 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0034 | 0.693 | 0.7724 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0039 | 0.8236 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0042 | 0.8972 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 2 uM | Antiviral activity against HIV1 by focal infectivity assay | ChEMBL. | 17074494 |
IC50 (ADMET) | = 7.8 uM | Cytotoxicity against HeLa H1-JC.37 cells by MTS assay | ChEMBL. | 17074494 |
IC50 (binding) | > 100 uM | Inhibition of HIV1 integrase-mediated 3'-processing activity | ChEMBL. | 17074494 |
IC50 (binding) | > 100 uM | Inhibition of HIV1 integrase-mediated integration activity | ChEMBL. | 17074494 |
IC50 (binding) | > 100 uM | Inhibition of HIV1 integrase-mediated 3'-processing activity | ChEMBL. | 17074494 |
IC50 (binding) | > 100 uM | Inhibition of HIV1 integrase-mediated integration activity | ChEMBL. | 17074494 |
Ratio IC50/EC50 (functional) | = 3.9 | Selectivity ratio of EC50 for HIV1 to IC50 for HeLa H1-JC.37 cells | ChEMBL. | 17074494 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.