Detailed information for compound 42155

Basic information

Technical information
  • TDR Targets ID: 42155
  • Name: benzyl N-[(2S)-1-[[(2S,3R)-2-(benzenesulfonyl )-4-oxoazetidin-3-yl]amino]-1-oxo-3-phenylpro pan-2-yl]carbamate
  • MW: 507.558 | Formula: C26H25N3O6S
  • H donors: 3 H acceptors: 5 LogP: 3.58 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(N[C@H](C(=O)N[C@@H]1C(=O)N[C@H]1S(=O)(=O)c1ccccc1)Cc1ccccc1)OCc1ccccc1
  • InChi: 1S/C26H25N3O6S/c30-23(28-22-24(31)29-25(22)36(33,34)20-14-8-3-9-15-20)21(16-18-10-4-1-5-11-18)27-26(32)35-17-19-12-6-2-7-13-19/h1-15,21-22,25H,16-17H2,(H,27,32)(H,28,30)(H,29,31)/t21-,22+,25-/m0/s1
  • InChiKey: JICMCJAFBMCIIX-FBLLAGFSSA-N  


Substructure search Similarity search

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Synonyms

  • benzyl N-[(1S)-2-[[(2S,3R)-2-(benzenesulfonyl)-4-oxo-azetidin-3-yl]amino]-1-benzyl-2-oxo-ethyl]carbamate
  • N-[(1S)-2-[[(2S,3R)-2-(benzenesulfonyl)-4-oxo-3-azetidinyl]amino]-1-benzyl-2-oxoethyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S)-1-oxo-1-[[(3R,4S)-2-oxo-4-(phenylsulfonyl)azetidin-3-yl]amino]-3-phenyl-propan-2-yl]carbamate
  • N-[(1S)-1-benzyl-2-[[(2S,3R)-2-besyl-4-keto-azetidin-3-yl]amino]-2-keto-ethyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S)-1-oxo-1-[[(3R,4S)-2-oxo-4-phenylsulfonylazetidin-3-yl]amino]-3-phenylpropan-2-yl]carbamate
  • phenylmethyl N-[(1S)-2-oxo-2-[[(3R,4S)-2-oxo-4-phenylsulfonyl-azetidin-3-yl]amino]-1-(phenylmethyl)ethyl]carbamate
  • N-[(1S)-2-oxo-2-[[(3R,4S)-2-oxo-4-phenylsulfonyl-3-azetidinyl]amino]-1-(phenylmethyl)ethyl]carbamic acid phenylmethyl ester
  • N-[(1S)-1-(benzyl)-2-keto-2-[[(3R,4S)-2-keto-4-phenylsulfonyl-azetidin-3-yl]amino]ethyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S)-1-oxo-1-[[(3R,4S)-2-oxo-4-phenylsulfonyl-azetidin-3-yl]amino]-3-phenyl-propan-2-yl]carbamate

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cathepsin L Starlite/ChEMBL References
Homo sapiens cathepsin K Starlite/ChEMBL References
Homo sapiens cathepsin S Starlite/ChEMBL References
Rattus norvegicus Cathepsin B Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania braziliensis cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Giardia lamblia Cathepsin B precursor Get druggable targets OG5_127800 All targets in OG5_127800
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma mansoni SmCB2 peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin B Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Giardia lamblia Cathepsin B precursor Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin B-like protease (Precursor), related Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01363 cathepsin B [EC3.4.22.1], putative Get druggable targets OG5_127800 All targets in OG5_127800
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cathepsin B Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin B-like cysteine proteinase Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase C (CPC), putative,CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like, putative Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania infantum cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase C (CPC), putative Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma cruzi cysteine peptidase C (CPC), putative Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Giardia lamblia Cathepsin B precursor Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Giardia lamblia Cathepsin L precursor Cathepsin B   339 aa 284 aa 21.8 %
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) Cathepsin B   339 aa 294 aa 28.9 %
Babesia bovis preprocathepsin c precursor, putative Cathepsin B   339 aa 282 aa 29.8 %
Theileria parva cathepsin C, putative Cathepsin B   339 aa 295 aa 26.1 %
Cryptosporidium hominis preprocathepsin c precursor Cathepsin B   339 aa 282 aa 29.4 %
Plasmodium falciparum cysteine proteinase falcipain 1 cathepsin L 333 aa 359 aa 30.1 %
Onchocerca volvulus Cathepsin B   339 aa 319 aa 38.9 %
Theileria parva cysteine proteinase, putative Cathepsin B   339 aa 305 aa 22.6 %
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase Cathepsin B   339 aa 287 aa 22.6 %
Plasmodium vivax dipeptidyl aminopeptidase 1, putative Cathepsin B   339 aa 304 aa 27.0 %
Plasmodium yoelii cathepsin c precursor Cathepsin B   339 aa 319 aa 27.0 %
Entamoeba histolytica cysteine protease, putative Cathepsin B   339 aa 275 aa 25.5 %
Giardia lamblia Dipeptidyl-peptidase I precursor Cathepsin B   339 aa 274 aa 27.7 %
Babesia bovis cathepsin C precursor, putative Cathepsin B   339 aa 304 aa 26.6 %
Dictyostelium discoideum cathepsin L-like proteinase Cathepsin B   339 aa 304 aa 28.9 %
Plasmodium knowlesi knowpain-2 Cathepsin B   339 aa 302 aa 24.8 %
Giardia lamblia Cathepsin L-like protease Cathepsin B   339 aa 303 aa 23.8 %
Plasmodium vivax unspecified product Cathepsin B   339 aa 297 aa 22.6 %
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) Cathepsin B   339 aa 327 aa 30.3 %
Plasmodium knowlesi knowpain-4 Cathepsin B   339 aa 304 aa 24.3 %
Schistosoma mansoni cathepsin F (C01 family) Cathepsin B   339 aa 273 aa 28.9 %
Dictyostelium discoideum cysteine proteinase 5 precursor Cathepsin B   339 aa 303 aa 22.4 %
Cryptosporidium parvum preprocathepsin c precursor, putative Cathepsin B   339 aa 287 aa 30.3 %
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Cathepsin B   339 aa 301 aa 23.6 %
Plasmodium falciparum serine repeat antigen 8 Cathepsin B   339 aa 272 aa 25.0 %
Brugia malayi Papain family cysteine protease containing protein Cathepsin B   339 aa 337 aa 21.4 %
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Cathepsin B   339 aa 298 aa 23.8 %
Entamoeba histolytica cysteine protease, putative Cathepsin B   339 aa 275 aa 22.5 %
Plasmodium knowlesi dipeptidyl aminopeptidase 2, putative Cathepsin B   339 aa 293 aa 26.6 %
Plasmodium vivax dipeptidyl aminopeptidase 2, putative Cathepsin B   339 aa 284 aa 26.4 %
Plasmodium falciparum cysteine proteinase falcipain 1 cathepsin S 281 aa 226 aa 34.1 %
Dictyostelium discoideum cysteine protease Cathepsin B   339 aa 283 aa 24.7 %
Toxoplasma gondii cathepsin CPC1 Cathepsin B   339 aa 310 aa 29.4 %
Plasmodium falciparum cysteine proteinase falcipain 1 cathepsin K 329 aa 349 aa 33.2 %
Neospora caninum hypothetical protein Cathepsin B   339 aa 321 aa 28.3 %
Schistosoma japonicum Cathepsin C precursor, putative Cathepsin B   339 aa 332 aa 26.8 %
Giardia lamblia Cathepsin L precursor Cathepsin B   339 aa 278 aa 27.0 %
Onchocerca volvulus Cathepsin B   339 aa 330 aa 35.2 %
Plasmodium berghei berghepain-1 Cathepsin B   339 aa 273 aa 19.8 %
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Cathepsin B   339 aa 302 aa 24.5 %
Plasmodium berghei dipeptidyl aminopeptidase 1, putative Cathepsin B   339 aa 319 aa 26.6 %
Giardia lamblia Cathepsin L precursor Cathepsin B   339 aa 285 aa 25.6 %
Schistosoma japonicum ko:K01275 cathepsin C [EC3.4.14.1], putative Cathepsin B   339 aa 334 aa 29.3 %
Onchocerca volvulus Cathepsin B-like cysteine proteinase 6 homolog Cathepsin B   339 aa 326 aa 51.2 %
Plasmodium falciparum cysteine proteinase falcipain 1 Cathepsin B   339 aa 283 aa 22.6 %
Schistosoma mansoni cathepsin F (C01 family) Cathepsin B   339 aa 273 aa 28.9 %
Schistosoma mansoni cathepsin F (C01 family) Cathepsin B   339 aa 273 aa 28.9 %
Plasmodium falciparum dipeptidyl aminopeptidase 2 Cathepsin B   339 aa 300 aa 27.3 %
Plasmodium vivax vivapain-1 Cathepsin B   339 aa 289 aa 22.5 %
Plasmodium falciparum dipeptidyl aminopeptidase 1 Cathepsin B   339 aa 367 aa 25.9 %
Plasmodium knowlesi dipeptidyl aminopeptidase 1, putative Cathepsin B   339 aa 312 aa 26.3 %
Giardia lamblia Encystation-specific protease Cathepsin B   339 aa 272 aa 23.5 %
Plasmodium yoelii cysteine proteinase precursor Cathepsin B   339 aa 273 aa 20.1 %
Plasmodium berghei dipeptidyl aminopeptidase 2 Cathepsin B   339 aa 314 aa 24.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.2924 1
Echinococcus granulosus cathepsin b 0.0181 1 1
Brugia malayi Papain family cysteine protease containing protein 0.0086 0.2924 0.2924
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.2924 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0086 0.2924 1
Onchocerca volvulus Cathepsin L homolog 0.0086 0.2924 1
Brugia malayi Cathepsin L-like precursor 0.0086 0.2924 0.2924
Leishmania major cathepsin L-like protease 0.0086 0.2924 1
Leishmania major cathepsin L-like protease 0.0086 0.2924 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.2924 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.2924 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.007 0.1716 0.5868
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1
Loa Loa (eye worm) fibroinase 0.0086 0.2924 0.2198
Giardia lamblia Cathepsin B precursor 0.007 0.1716 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.2924 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0181 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.2924 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.2924 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0086 0.2924 0.2198
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.2924 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0086 0.2924 0.2924
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1
Onchocerca volvulus 0.0086 0.2924 1
Schistosoma mansoni cathepsin F (C01 family) 0.0059 0.093 0.093
Giardia lamblia Cathepsin B precursor 0.007 0.1716 0.5
Onchocerca volvulus 0.0086 0.2924 1
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0181 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1
Trypanosoma cruzi cysteine peptidase, putative 0.0086 0.2924 0.2924
Onchocerca volvulus 0.0086 0.2924 1
Onchocerca volvulus 0.0086 0.2924 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0181 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.2924 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.2924 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0086 0.2924 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0181 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0086 0.2924 1
Brugia malayi Cathepsin L-like precursor 0.0086 0.2924 0.2924
Brugia malayi Cathepsin L-like cysteine proteinase 0.0059 0.093 0.093
Loa Loa (eye worm) cathepsin B 0.007 0.1716 0.0866
Echinococcus granulosus cathepsin l1 0.0086 0.2924 0.2924
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.007 0.1716 0.1716
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0086 0.2924 0.2924
Echinococcus multilocularis cysteine protease 0.0086 0.2924 0.2924
Plasmodium vivax vivapain-2 0.0086 0.2924 1
Brugia malayi Cathepsin L-like precursor 0.0086 0.2924 0.2924
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.093 0.3182
Trypanosoma cruzi cysteine peptidase, putative 0.0086 0.2924 0.2924
Onchocerca volvulus 0.0086 0.2924 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.2924 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1
Giardia lamblia Cathepsin B precursor 0.007 0.1716 0.5
Echinococcus multilocularis cysteine protease 0.0086 0.2924 0.2924
Entamoeba histolytica cysteine proteinase, putative 0.0059 0.093 0.3182
Echinococcus multilocularis cathepsin L cysteine protease 0.0086 0.2924 0.2924
Leishmania major cathepsin L-like protease 0.0086 0.2924 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.2924 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.2924 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0086 0.2924 1
Brugia malayi Cathepsin L-like precursor 0.0086 0.2924 0.2924
Onchocerca volvulus 0.0086 0.2924 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0086 0.2924 0.2198
Entamoeba histolytica cysteine protease, putative 0.0086 0.2924 1
Echinococcus multilocularis cathepsin b 0.0181 1 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.093 0.093
Plasmodium vivax vivapain-2 0.0086 0.2924 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0181 1 1
Loa Loa (eye worm) cysteine protease 0.0086 0.2924 0.2198
Leishmania major cathepsin L-like protease 0.0086 0.2924 1
Brugia malayi Cathepsin L-like precursor 0.0059 0.093 0.093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.2924 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.2924 1
Leishmania major cathepsin L-like protease 0.0086 0.2924 1
Leishmania major cathepsin L-like protease 0.0086 0.2924 1
Echinococcus granulosus cathepsin l1 0.0059 0.093 0.093
Loa Loa (eye worm) hypothetical protein 0.0086 0.2924 0.2198
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.2924 1
Entamoeba histolytica cysteine proteinase, putative 0.0086 0.2924 1
Trypanosoma cruzi cruzipain precursor, putative 0.0086 0.2924 0.2924
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1
Leishmania major cathepsin L-like protease 0.0086 0.2924 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.007 0.1716 0.5868
Brugia malayi Cathepsin L-like precursor 0.0086 0.2924 0.2924
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.2924 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.007 0.1716 0.1716
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.2924 1
Schistosoma mansoni cathepsin F (C01 family) 0.0086 0.2924 0.2924
Echinococcus multilocularis cathepsin L cysteine protease 0.0086 0.2924 0.2924
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.2924 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0086 0.2924 0.2924
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1
Loa Loa (eye worm) ctsf protein 0.0086 0.2924 0.2198
Trypanosoma cruzi cysteine peptidase, putative 0.0086 0.2924 0.2924
Onchocerca volvulus 0.0086 0.2924 1
Echinococcus granulosus cathepsin b 0.0181 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0086 0.2924 0.2924
Schistosoma mansoni cathepsin F (C01 family) 0.0086 0.2924 0.2924
Leishmania major cysteine peptidase A (CPA) 0.0086 0.2924 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1
Entamoeba histolytica cysteine proteinase, putative 0.0086 0.2924 1
Loa Loa (eye worm) hypothetical protein 0.0181 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.093 0.3182
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0086 0.2924 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1
Leishmania major cathepsin L-like protease 0.0086 0.2924 1
Brugia malayi Cathepsin L-like precursor 0.0086 0.2924 0.2924
Onchocerca volvulus Cathepsin F homolog 0.0086 0.2924 1
Brugia malayi cathepsin L-like precursor 0.0059 0.093 0.093
Brugia malayi Cathepsin L-like precursor 0.0059 0.093 0.093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.2924 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0086 0.2924 0.2924
Toxoplasma gondii cathepsin CPL 0.0086 0.2924 1
Echinococcus multilocularis cathepsin b 0.0181 1 1
Onchocerca volvulus Cathepsin L homolog 0.0086 0.2924 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.2924 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.0001 uM Inhibition of recombinant human Cathepsin L ChEMBL. 12467634
IC50 (binding) = 0.0001 uM Inhibition of recombinant human Cathepsin L ChEMBL. 12467634
IC50 (binding) = 0.0065 uM Inhibition of recombinant human Cathepsin K ChEMBL. 12467634
IC50 (binding) = 0.0065 uM Inhibition of recombinant human Cathepsin K ChEMBL. 12467634
IC50 (binding) = 0.048 uM Inhibition of recombinant human cathepsin S ChEMBL. 12467634
IC50 (binding) = 0.048 uM Inhibition of recombinant human cathepsin S ChEMBL. 12467634
IC50 (binding) = 7.39 uM Inhibition of recombinant rat Cathepsin B ChEMBL. 12467634
IC50 (binding) = 7.39 uM Inhibition of recombinant rat Cathepsin B ChEMBL. 12467634
IC50 (binding) > 50 uM Inhibition of human leukocyte elastase(HLE) ChEMBL. 12467634
IC50 (binding) > 50 uM Inhibition of human leukocyte elastase(HLE) ChEMBL. 12467634

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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