Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0666 | 1 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0314 | 0.459 | 0.4559 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0666 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0666 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.1123 | 0.1072 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0666 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0666 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0314 | 0.459 | 0.444 |
Schistosoma mansoni | nuclear hormone receptor | 0.0314 | 0.459 | 0.4559 |
Schistosoma mansoni | coup transcription factor | 0.0666 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0666 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0314 | 0.459 | 0.444 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0666 | 1 | 1 |
Mycobacterium ulcerans | glutaminase | 0.0267 | 0.3869 | 0.5 |
Brugia malayi | nuclear receptor RXR | 0.0352 | 0.517 | 0.5142 |
Brugia malayi | steroid hormone receptor | 0.0666 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 1 | 1 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0327 | 0.4781 | 0.4635 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | glutaminase | 0.0267 | 0.3869 | 0.3869 |
Echinococcus granulosus | FTZ F1 alpha | 0.0666 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0666 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0352 | 0.517 | 0.5142 |
Schistosoma mansoni | nuclear hormone receptor | 0.0666 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0352 | 0.517 | 0.5142 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0666 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0666 | 1 | 1 |
Onchocerca volvulus | 0.0314 | 0.459 | 0.4216 | |
Brugia malayi | hypothetical protein | 0.0352 | 0.517 | 0.5142 |
Schistosoma mansoni | thyroid hormone receptor | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0666 | 1 | 1 |
Onchocerca volvulus | 0.0112 | 0.1483 | 0.0894 | |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0511 | 0.0511 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0099 | 0.1274 | 0.1274 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0666 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0314 | 0.459 | 0.4559 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0352 | 0.517 | 0.5142 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.459 | 0.459 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.1123 | 0.0875 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0089 | 0.1123 | 0.1072 |
Loa Loa (eye worm) | glutaminase 2 | 0.0267 | 0.3869 | 0.3869 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0666 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0058 | 0.0647 | 0.0593 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0666 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0666 | 1 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0314 | 0.459 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.459 | 0.459 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0314 | 0.459 | 0.4559 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0314 | 0.459 | 0.459 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0352 | 0.517 | 0.5142 |
Loa Loa (eye worm) | DR-78 | 0.0314 | 0.459 | 0.459 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0666 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0666 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0666 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0352 | 0.517 | 0.5035 |
Loa Loa (eye worm) | glutamate receptor | 0.004 | 0.037 | 0.037 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.1123 | 0.0875 |
Brugia malayi | ecdysone receptor | 0.0314 | 0.459 | 0.4559 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0666 | 1 | 1 |
Trichomonas vaginalis | glutaminase, putative | 0.0267 | 0.3869 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0666 | 1 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0314 | 0.459 | 0.4559 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0352 | 0.517 | 0.5035 |
Loa Loa (eye worm) | hypothetical protein | 0.0352 | 0.517 | 0.517 |
Echinococcus granulosus | geminin | 0.0165 | 0.2292 | 0.2078 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0314 | 0.459 | 0.4559 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0314 | 0.459 | 0.459 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0666 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0666 | 1 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0314 | 0.459 | 0.444 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0314 | 0.459 | 0.4559 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0314 | 0.459 | 0.459 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.1123 | 0.1072 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0666 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.1123 | 0.0875 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0666 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0314 | 0.459 | 0.444 |
Echinococcus multilocularis | geminin | 0.0165 | 0.2292 | 0.2078 |
Loa Loa (eye worm) | hypothetical protein | 0.0352 | 0.517 | 0.517 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0314 | 0.459 | 0.444 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0352 | 0.517 | 0.517 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0666 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.459 | 0.459 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.459 | 0.459 |
Brugia malayi | tailless protein | 0.0314 | 0.459 | 0.4559 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0666 | 1 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0045 | 0.0454 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.459 | 0.459 |
Loa Loa (eye worm) | hypothetical protein | 0.0352 | 0.517 | 0.517 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 1 | 1 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.004 | 0.037 | 0.0315 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0352 | 0.517 | 0.5142 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0666 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0314 | 0.459 | 0.444 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0314 | 0.459 | 0.4216 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0314 | 0.459 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.459 | 0.459 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0666 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0666 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0666 | 1 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0314 | 0.459 | 0.4559 |
Brugia malayi | nuclear receptor NHR-67 | 0.0314 | 0.459 | 0.4559 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0314 | 0.459 | 0.4559 |
Brugia malayi | conserved hypotetical protein | 0.0314 | 0.459 | 0.4559 |
Brugia malayi | Pre-SET motif family protein | 0.0099 | 0.1274 | 0.1224 |
Brugia malayi | nuclear receptor RXR | 0.0314 | 0.459 | 0.4559 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0666 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0666 | 1 | 1 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0314 | 0.459 | 0.4559 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0666 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0314 | 0.459 | 0.4559 |
Onchocerca volvulus | 0.0666 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0647 | 0.0647 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0666 | 1 | 1 |
Brugia malayi | glutaminase DH11.1 | 0.0267 | 0.3869 | 0.3833 |
Schistosoma mansoni | thyroid hormone receptor | 0.0666 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0314 | 0.459 | 0.4559 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.1123 | 0.0875 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0666 | 1 | 1 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0049 | 0.0511 | 0.0247 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.2292 | 0.2248 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0647 | 0.0647 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0666 | 1 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0314 | 0.459 | 0.444 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.1123 | 0.1072 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0666 | 1 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0314 | 0.459 | 0.4559 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0049 | 0.0511 | 0.0247 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0314 | 0.459 | 0.444 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0314 | 0.459 | 0.4559 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.459 | 0.459 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.459 | 0.459 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.459 | 0.459 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.459 | 0.459 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0666 | 1 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0327 | 0.4781 | 0.4635 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0314 | 0.459 | 0.4559 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0089 | 0.1123 | 0.1123 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0033 | 0.0271 | 0.0215 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0666 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0666 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0666 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0314 | 0.459 | 0.4559 |
Schistosoma mansoni | glutaminase | 0.0267 | 0.3869 | 0.3833 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0352 | 0.517 | 0.517 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0314 | 0.459 | 0.444 |
Loa Loa (eye worm) | hypothetical protein | 0.0352 | 0.517 | 0.517 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0666 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0314 | 0.459 | 0.4559 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.2292 | 0.2248 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0314 | 0.459 | 0.444 |
Onchocerca volvulus | 0.0314 | 0.459 | 0.4216 | |
Schistosoma mansoni | microtubule-associated protein tau | 0.0327 | 0.4781 | 0.4751 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.459 | 0.459 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.459 | 0.459 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.459 | 0.459 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0314 | 0.459 | 0.4216 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0036 | 0.0313 | 0.0257 |
Brugia malayi | nuclear receptor NHR-88 | 0.0314 | 0.459 | 0.4559 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.