Detailed information for compound 423106

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 567.718 | Formula: C28H49N5O7
  • H donors: 5 H acceptors: 6 LogP: 3.26 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCC1CC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O1)C(C)C)C)CC(C)C
  • InChi: 1S/C28H49N5O7/c1-9-10-11-19-13-21(34)29-14-22(35)32-23(16(4)5)27(38)31-20(12-15(2)3)26(37)30-18(8)25(36)33-24(17(6)7)28(39)40-19/h15-20,23-24H,9-14H2,1-8H3,(H,29,34)(H,30,37)(H,31,38)(H,32,35)(H,33,36)/t18-,19?,20+,23-,24-/m0/s1
  • InChiKey: MMGAMUCWYNLSNI-OUQCLNPOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus expressed conserved protein 0.0187 0.104 0.1697
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0039 0.015 0.0414
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0039 0.015 0.0757
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0039 0.015 0.0422
Echinococcus granulosus Protein patched homolog 1 0.0086 0.0431 0.0698
Echinococcus granulosus Niemann Pick C1 protein 0.0285 0.1624 0.2657
Echinococcus granulosus survival motor neuron protein 1 0.0249 0.1411 0.2307
Toxoplasma gondii exonuclease III APE 0.002 0.0038 0.0083
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0192 0.0984
Echinococcus granulosus tar DNA binding protein 0.0125 0.0668 0.1087
Brugia malayi jmjC domain containing protein 0.0057 0.026 0.0737
Loa Loa (eye worm) hypothetical protein 0.0303 0.1733 0.4895
Loa Loa (eye worm) oxidoreductase 0.0039 0.015 0.0399
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0039 0.015 0.0757
Echinococcus granulosus sterol regulatory element binding protein 0.0086 0.0431 0.0698
Schistosoma mansoni hypothetical protein 0.0082 0.0412 0.0677
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.015 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0431 0.1216
Mycobacterium tuberculosis Conserved hypothetical protein 0.0171 0.0944 0.2803
Echinococcus multilocularis expressed conserved protein 0.0187 0.104 0.1034
Mycobacterium ulcerans hypothetical protein 0.0201 0.112 0.3308
Brugia malayi MH2 domain containing protein 0.0041 0.0165 0.0467
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0066 0.0315 0.0917
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0039 0.015 0.0374
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0066 0.0315 0.1643
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0315 0.0864
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0063 0.0178
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0064 0.0299 0.0294
Echinococcus granulosus phd:f box containing protein 0.0015 0.001 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0072 0.0129
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0066 0.0315 0.0864
Brugia malayi jmjC domain containing protein 0.0015 0.001 0.0028
Entamoeba histolytica 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein 0.0066 0.0315 0.2558
Brugia malayi Calcitonin receptor-like protein seb-1 0.0201 0.1121 0.3177
Schistosoma mansoni hypothetical protein 0.0082 0.0412 0.0677
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0066 0.0315 0.1643
Echinococcus multilocularis geminin 0.1033 0.6096 0.6094
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0154 0.1071
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.001 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0063 0.0178
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.002 0.0024
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0765 0.1247
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0026 0.0073
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0064 0.0299 0.0482
Echinococcus granulosus Niemann Pick C1 protein 0.0199 0.1112 0.1816
Loa Loa (eye worm) hypothetical protein 0.0066 0.0315 0.0866
Echinococcus granulosus mothers against decapentaplegic 2 0.0018 0.0029 0.0038
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0571 0.3334 1
Brugia malayi Muscleblind-like protein 0.0303 0.1733 0.491
Schistosoma mansoni ap endonuclease 0.002 0.0038 0.0062
Onchocerca volvulus 0.0051 0.0223 0.1658
Schistosoma mansoni phd/f-box containing protein 0.0015 0.001 0.0016
Brugia malayi Heterochromatin protein 1 0.0075 0.0368 0.1042
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0325 0.1864 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0063 0.0285
Brugia malayi hypothetical protein 0.0016 0.0017 0.0049
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0064 0.0299 0.0294
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0389 0.1095
Loa Loa (eye worm) hypothetical protein 0.0201 0.112 0.3155
Schistosoma mansoni hypothetical protein 0.0834 0.4906 0.8048
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0056 0.0252 0.1307
Schistosoma mansoni hypothetical protein 0.0064 0.0299 0.0491
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0206 0.1151 0.6155
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0039 0.015 0.0422
Trichomonas vaginalis hypothetical protein 0.0571 0.3334 1
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0039 0.015 0.0374
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0063 0.0178
Schistosoma mansoni hypothetical protein 0.0064 0.0299 0.0491
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.002 0.0024
Echinococcus multilocularis mothers against decapentaplegic 2 0.0018 0.0029 0.0023
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.015 0.0374
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0027 0.0021
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.079 0.2237
Brugia malayi RNA binding protein 0.0125 0.0668 0.1892
Brugia malayi latrophilin 2 splice variant baaae 0.0137 0.0741 0.2099
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0154 0.4188
Echinococcus granulosus smad 0.0041 0.0165 0.0261
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0026 0.0049
Plasmodium falciparum polyprenol reductase, putative 0.0066 0.0315 0.0917
Echinococcus granulosus chromobox protein 1 0.0075 0.0368 0.0594
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0039 0.015 0.0374
Brugia malayi CHD4 protein 0.0016 0.0012 0.0035
Loa Loa (eye worm) hypothetical protein 0.0024 0.0063 0.015
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0038 0.0026
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0026 0.0041
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0325 0.1864 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0064 0.0299 0.0848
Echinococcus multilocularis phd:f box containing protein 0.0015 0.001 0.0004
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0125 0.0668 0.1869
Echinococcus multilocularis protein dispatched 1 0.0098 0.0503 0.0498
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0027 0.0035
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0303 0.1733 0.4895
Schistosoma mansoni hypothetical protein 0.0082 0.0412 0.0677
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0039 0.015 0.0246
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.015 0.0374
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.028 0.0459
Trichomonas vaginalis chromobox protein, putative 0.0045 0.019 0.0485
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0389 0.1095
Brugia malayi jmjC domain containing protein 0.0015 0.001 0.0028
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0026 0.0049
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0175 0.0441
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.015 0.0374
Plasmodium falciparum 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0066 0.0315 0.0917
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0039 0.015 0.0267
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0668 0.1095
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0039 0.015 0.0342
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.002 0.0024
Schistosoma mansoni hypothetical protein 0.0082 0.0412 0.0677
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0571 0.3334 1
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0039 0.015 0.0414
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0175 0.0278
Schistosoma mansoni hypothetical protein 0.1033 0.6096 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.0546 0.1523
Trypanosoma brucei beta lactamase 0.0063 0.0297 0.1547
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.017 0.0428
Trichomonas vaginalis chromobox protein, putative 0.0045 0.019 0.0485
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0039 0.015 0.0237
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0071 0.0184
Brugia malayi MH1 domain containing protein 0.0023 0.0055 0.0156
Brugia malayi Synaptic glycoprotein SC2 0.0066 0.0315 0.0891
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.002 0.0024
Echinococcus granulosus Smad4 0.0041 0.0165 0.0261
Echinococcus granulosus muscleblind protein 0.0303 0.1733 0.2836
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0066 0.0315 0.0917
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0063 0.011
Brugia malayi isocitrate dehydrogenase 0.0016 0.0013 0.0036
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0013 0.0008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.015 0.0374
Brugia malayi Smad1 0.0041 0.0165 0.0467
Echinococcus multilocularis lysine specific demethylase 5A 0.0057 0.026 0.0254
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0066 0.0315 0.0864
Brugia malayi hypothetical protein 0.0249 0.1411 0.3997
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0013 0.0015
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.0604 0.1786
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0047
Schistosoma mansoni smad 0.0018 0.0029 0.0047
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0154 0.0432
Giardia lamblia Synaptic glycoprotein SC2 0.0066 0.0315 1
Brugia malayi TAR-binding protein 0.0125 0.0668 0.1892
Loa Loa (eye worm) Smad1 0.0041 0.0165 0.044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0047
Brugia malayi hypothetical protein 0.0025 0.0071 0.0201
Entamoeba histolytica steroid 5-alpha reductase, putative 0.0201 0.112 1
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0039 0.015 0.0422
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0201 0.112 0.3302
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0063 0.011
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0389 0.0628
Onchocerca volvulus 0.0033 0.0116 0.0862
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0041 0.0165 0.0271
Echinococcus multilocularis muscleblind protein 1 0.0303 0.1733 0.1728
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0039 0.015 0.0144
Echinococcus multilocularis synaptic glycoprotein sc2 0.0066 0.0315 0.0309
Brugia malayi S-adenosyl-methionine cycloartenol-C24-methyltransferase 0.01 0.0519 0.1472
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.1285 0.2101
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0039 0.015 0.0757
Echinococcus multilocularis Smad4 0.0041 0.0165 0.0159
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0012 0.0011
Echinococcus granulosus cpg binding protein 0.0062 0.0289 0.0465
Leishmania major sterol 24-c-methyltransferase, putative 0.0206 0.1151 0.6155
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0269 0.0736
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0081 0.123
Onchocerca volvulus 0.0024 0.0063 0.0466
Schistosoma mansoni chromobox protein 0.0075 0.0368 0.0603
Schistosoma mansoni jumonji domain containing protein 0.0015 0.001 0.0016
Mycobacterium ulcerans hypothetical protein 0.0171 0.0944 0.2773
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0175 0.0496
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.015 0.0374
Loa Loa (eye worm) hypothetical protein 0.0066 0.0315 0.0866
Brugia malayi MH2 domain containing protein 0.0604 0.353 1
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.0201 0.112 0.5989
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0063 0.0151
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0201 0.112 0.5989
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.028 0.0768
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0038 0.0106
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0013 0.0021
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0027 0.0049
Echinococcus granulosus dnaJ subfamily B 0.0834 0.4906 0.8046
Leishmania major mitochondrial DNA polymerase beta 0.0325 0.1864 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0063 0.0232
Brugia malayi MH1 domain containing protein 0.0041 0.0165 0.0467
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0012 0.0007
Brugia malayi jmjC domain containing protein 0.0015 0.001 0.0028
Trypanosoma brucei Sterol methyltransferase, putative 0.0206 0.1151 0.6155
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0389 0.1139
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.1285 0.128
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0039 0.015 0.0374
Onchocerca volvulus 0.0066 0.0315 0.2337
Leishmania major pteridine reductase 1 0.0039 0.015 0.0757
Schistosoma mansoni cpg binding protein 0.0062 0.0289 0.0474
Plasmodium vivax polyprenol reductase, putative 0.0066 0.0315 0.0917
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0013 0.0011
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0132 0.0706 0.2087
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0571 0.3334 1
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0389 1
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0389 0.1095
Leishmania major hypothetical protein, conserved 0.0025 0.0071 0.033
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0013 0.0015
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.019 0.1408
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0071 0.0184
Schistosoma mansoni Smad4 0.0041 0.0165 0.0271
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0029 0.0054
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.079 0.0784
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0038 0.0026
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0066 0.0315 0.0864
Brugia malayi jmjC domain containing protein 0.006 0.028 0.0793
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0063 0.011
Loa Loa (eye worm) hypothetical protein 0.0024 0.0063 0.015
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0389 0.1139
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.001 0.0016
Brugia malayi Niemann-Pick C1 protein precursor 0.0199 0.1112 0.315
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.0066 0.0315 0.0507
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.0201 0.112 0.3174
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0039 0.015 0.0414
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0066 0.0315 0.0516
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0013 0.0007
Brugia malayi mothers against decapentaplegic homolog 3 0.0018 0.0029 0.0082
Brugia malayi jmjC domain containing protein 0.0015 0.001 0.0028
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.015 0.0374
Entamoeba histolytica hypothetical protein 0.0066 0.0315 0.2558
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0063 0.011
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0013 0.0008
Loa Loa (eye worm) MH1 domain-containing protein 0.0041 0.0165 0.044
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0039 0.015 0.0399
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0137 0.0741 0.2077
Schistosoma mansoni jumonji domain containing protein 0.0057 0.026 0.0427
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0038 0.0149
Echinococcus multilocularis survival motor neuron protein 1 0.0249 0.1411 0.1406
Loa Loa (eye worm) hypothetical protein 0.0042 0.017 0.0456
Onchocerca volvulus 0.0239 0.1346 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.0389 0.1076
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0071 0.033
Brugia malayi chromobox protein homolog 3 0.0042 0.017 0.0483
Brugia malayi MH2 domain containing protein 0.0018 0.0029 0.0082
Loa Loa (eye worm) hypothetical protein 0.0064 0.0299 0.0822
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.001 0.0007
Echinococcus granulosus chromobox protein 1 0.0075 0.0368 0.0594
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0038 0.0032
Loa Loa (eye worm) TAR-binding protein 0.0125 0.0668 0.1869
Loa Loa (eye worm) hypothetical protein 0.0159 0.0871 0.2447
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0006 0.001
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0039 0.015 0.0414
Brugia malayi MH2 domain containing protein 0.0041 0.0165 0.0467
Schistosoma mansoni hypothetical protein 0.0137 0.0741 0.1215
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0201 0.112 0.3302
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.1285 0.2108
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0071 0.0184
Onchocerca volvulus Bile acid receptor homolog 0.0159 0.0871 0.6472
Echinococcus multilocularis mothers against decapentaplegic 5 0.0041 0.0165 0.0159
Echinococcus granulosus geminin 0.1033 0.6096 1
Brugia malayi CXXC zinc finger family protein 0.0059 0.0269 0.0762
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0039 0.015 0.0374
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0154 0.084 0.4474
Loa Loa (eye worm) hypothetical protein 0.0025 0.0071 0.0174
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0192 0.0984
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0038 0.0149
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0038 0.0034
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.015 0.0374
Loa Loa (eye worm) nuclear factor I 0.0023 0.0055 0.0128
Trypanosoma brucei pteridine reductase 1 0.0039 0.015 0.0757
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0206 0.1151 0.6155
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0012 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0072 0.0129
Mycobacterium tuberculosis Possible oxidoreductase 0.0039 0.015 0.0414
Echinococcus multilocularis muscleblind protein 0.0303 0.1733 0.1728
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0063 0.011
Loa Loa (eye worm) hypothetical protein 0.0086 0.0431 0.1196
Echinococcus multilocularis smad 0.0041 0.0165 0.0159
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0047
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0039 0.015 0.0757
Loa Loa (eye worm) hypothetical protein 0.0039 0.015 0.0399
Onchocerca volvulus 0.0059 0.0269 0.1999
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0029 0.0054
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0063 0.011
Loa Loa (eye worm) latrophilin receptor protein 2 0.0064 0.0299 0.0822
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.1285 0.2101
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0571 0.3334 1
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.0066 0.0315 0.0309
Echinococcus multilocularis dnaJ subfamily B 0.0834 0.4906 0.4903
Plasmodium falciparum enoyl-acyl carrier reductase 0.0571 0.3334 1
Mycobacterium ulcerans lipoprotein LpqF 0.0063 0.0297 0.0817
Echinococcus granulosus mothers against decapentaplegic 6 0.0018 0.0029 0.0038
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.001 0.0004
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0389 0.1139
Echinococcus multilocularis sterol regulatory element binding protein 0.0086 0.0431 0.0425
Echinococcus granulosus TGF beta signal transducer SmadC 0.0041 0.0165 0.0261
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0201 0.112 0.5989
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0039 0.015 0.0422
Entamoeba histolytica trans-2,3-enoyl-CoA reductase, putative 0.0066 0.0315 0.2558
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.015 0.0374
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0571 0.3334 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0063 0.0285
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.1285 0.128
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0175 0.0496
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0039 0.015 0.0374
Echinococcus multilocularis chromobox protein 1 0.0075 0.0368 0.0362
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0201 0.112 0.3341
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0206 0.1151 0.6155
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0038 0.0083
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0081 0.0213
Loa Loa (eye worm) RNA binding protein 0.0125 0.0668 0.1869
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0039 0.015 0.104
Brugia malayi RNA recognition motif domain containing protein 0.0125 0.0668 0.1892
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0192 0.0984
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0097 0.0205
Echinococcus multilocularis mothers against decapentaplegic 6 0.0018 0.0029 0.0023
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0322 0.1846 0.5521
Schistosoma mansoni hypothetical protein 0.0064 0.0299 0.0491
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0097 0.0205
Brugia malayi ecdysteroid receptor 0.0159 0.0871 0.2468
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.017 0.1266
Brugia malayi MH1 domain containing protein 0.0023 0.0055 0.0156
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0206 0.1151 0.6155
Schistosoma mansoni cpg binding protein 0.0059 0.0269 0.0441
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0368 0.1024
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0039 0.015 0.0757
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.015 0.0374
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0066 0.0315 0.0516
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0013 0.0007
Schistosoma mansoni smad1 5 8 and 0.0041 0.0165 0.0271
Schistosoma mansoni smad1 5 8 and 0.0041 0.0165 0.0271
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.015 0.0374
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0041 0.0165 0.0159
Echinococcus multilocularis Niemann Pick C1 protein 0.0285 0.1624 0.1619
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0081 0.0213
Echinococcus multilocularis GPCR, family 2 0.0064 0.0299 0.0294
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0064 0.0299 0.0482
Trypanosoma brucei oxidoreductase-like protein 0.0039 0.015 0.0757
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0223 0.0632
Brugia malayi Pax transcription factor protein 2 0.0239 0.1346 0.3814
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0066 0.0315 0.0917
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0368 0.1016
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0013 0.0008
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.001 0.0007
Schistosoma mansoni smad 0.0041 0.0165 0.0271
Onchocerca volvulus 0.0039 0.015 0.1116
Onchocerca volvulus 0.0039 0.015 0.1116
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0038 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0668 0.1095
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0063 0.0232
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0227 0.0221
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0228 0.1285 0.3623
Loa Loa (eye worm) hypothetical protein 0.01 0.0519 0.1448
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0072 0.0129
Schistosoma mansoni protein phosphatase 2C 0.0015 0.001 0.0016
Leishmania major oxidoreductase-like protein 0.0039 0.015 0.0757
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0227 0.0645
Loa Loa (eye worm) hypothetical protein 0.0249 0.1411 0.398
Brugia malayi CHE-14 protein 0.0086 0.0431 0.1221
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.015 0.0374
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0227 0.0363
Echinococcus multilocularis tar DNA binding protein 0.0125 0.0668 0.0662
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.015 0.0374
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0039 0.015 0.0757
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0154 0.084 0.4474
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0039 0.015 0.0374
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.0201 0.112 0.5989
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.015 0.0425
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0116 0.0302
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.015 0.0374
Brugia malayi Latrophilin receptor protein 2 0.0064 0.0299 0.0848
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0389 0.0383
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0107 0.0562 0.2975
Mycobacterium tuberculosis Probable oxidoreductase 0.0039 0.015 0.0414
Schistosoma mansoni survival motor neuron protein 0.0051 0.0223 0.0366
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0063 0.0151
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0081 0.0055
Echinococcus multilocularis cpg binding protein 0.0062 0.0289 0.0283
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0201 0.1121 0.3177
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0047
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0389 0.1139
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0175 0.0441
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0071 0.033
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0389 0.1095
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0013 0.0007
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0227 0.0502
Schistosoma mansoni dihydropteridine reductase 0.0039 0.015 0.0246
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.001 0.0007
Mycobacterium ulcerans epoxide hydrolase EphA 0.0322 0.1846 0.5502
Loa Loa (eye worm) hypothetical protein 0.0024 0.0063 0.015
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0063 0.011
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.015 0.0374
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.028 0.0459
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0039 0.015 0.0374
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0039 0.015 0.0422
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0227 0.0645
Loa Loa (eye worm) hypothetical protein 0.0023 0.0055 0.0128
Loa Loa (eye worm) MH2 domain-containing protein 0.0041 0.0165 0.044
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0368 0.1024
Echinococcus granulosus mothers against decapentaplegic 5 0.0041 0.0165 0.0261
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0063 0.0232
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0038 0.0083
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0389 0.0638
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0571 0.3334 1
Echinococcus granulosus GPCR family 2 0.0064 0.0299 0.0482
Echinococcus multilocularis protein patched 0.0086 0.0431 0.0425
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.015 0.0374
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0013 0.0015
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0325 0.1864 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0054
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0668 0.1095
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0038 0.0149
Loa Loa (eye worm) retinol dehydrogenase 12 0.0039 0.015 0.0399
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0039 0.015 0.0425
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0013 0.0008
Loa Loa (eye worm) pax transcription factor protein 2 0.0239 0.1346 0.3796
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0039 0.015 0.0414
Loa Loa (eye worm) hypothetical protein 0.0201 0.1121 0.3158
Schistosoma mansoni Smad4 0.0018 0.0029 0.0047
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.003 0.0024
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0013 0.0007
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0013 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0072 0.0129
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0063 0.0285
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0072 0.0129
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0013 0.0036
Schistosoma mansoni cpg binding protein 0.0062 0.0289 0.0474
Loa Loa (eye worm) acetyltransferase 0.0146 0.079 0.2215
Schistosoma mansoni hypothetical protein 0.1033 0.6096 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0057 0.026 0.0254
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0203 0.113 0.1854
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0071 0.0184
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0201 0.1121 0.3158
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.1285 0.2108
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0038 0.0079
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0063 0.0297 0.0855
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.001 0.0004
Brugia malayi Probable ClpP-like protease 0.0079 0.0389 0.1101
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0066 0.0315 0.0864
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.015 0.0374
Echinococcus multilocularis Niemann Pick C1 protein 0.0199 0.1112 0.1107
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0039 0.015 0.0757
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0192 0.0984
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0072 0.0129
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0571 0.3334 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0389 0.0996
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0668 0.1095
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0057 0.026 0.0417
Mycobacterium tuberculosis Possible oxidoreductase 0.0039 0.015 0.0414
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0086 0.0431 0.1196
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0071 0.033
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0668 0.1095
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.028 0.045
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0035 0.0018
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.015 0.0374
Toxoplasma gondii hypothetical protein 0.0027 0.0081 0.0213
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0154 0.084 0.4474
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.0662 0.1085
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0035 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.017 0.0428
Schistosoma mansoni patched 1 0.0086 0.0431 0.0707
Schistosoma mansoni ap endonuclease 0.002 0.0038 0.0062
Schistosoma mansoni Smad4 0.0018 0.0029 0.0047
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0039 0.015 0.0374
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0199 0.1112 0.9921
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0206 0.1151 0.6155
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0315 0.0864
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.003 0.0039
Leishmania major sterol 24-c-methyltransferase, putative 0.0206 0.1151 0.6155
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0013 0.0015
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0175 0.0496
Mycobacterium ulcerans hypothetical protein 0.0024 0.0063 0.011
Schistosoma mansoni hypothetical protein 0.0051 0.0223 0.0366
Loa Loa (eye worm) hypothetical protein 0.0199 0.1112 0.3131
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0132 0.0706 0.2055
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0072 0.0129
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0072 0.0129
Toxoplasma gondii hypothetical protein 0.0052 0.0233 0.067
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0201 0.112 0.3302
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0228 0.1285 0.3641
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.1285 0.2108
Loa Loa (eye worm) MH2 domain-containing protein 0.0604 0.353 1
Schistosoma mansoni smad1 5 8 and 0.0041 0.0165 0.0271
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0038 0.0149
Brugia malayi MH1 domain containing protein 0.0041 0.0165 0.0467
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0063 0.0297 0.0715
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0047
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0039 0.015 0.0267
Loa Loa (eye worm) transcription factor SMAD2 0.0604 0.353 1
Mycobacterium ulcerans oxidoreductase 0.0039 0.015 0.0374
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.079 0.1295
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0039 0.015 0.0414
Echinococcus multilocularis chromobox protein 1 0.0075 0.0368 0.0362
Schistosoma mansoni chromobox protein 0.0075 0.0368 0.0603
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0039 0.015 0.0374
Schistosoma mansoni hypothetical protein 0.0064 0.0299 0.0491
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0389 0.1065
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0018 0.0029 0.0214
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0038 0.0075
Mycobacterium ulcerans short chain dehydrogenase 0.0039 0.015 0.0374
Echinococcus granulosus synaptic glycoprotein sc2 0.0066 0.0315 0.0507
Chlamydia trachomatis oxoacy-ACP reductase 0.0039 0.015 0.0374

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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