Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Cytochrome P450 family protein | 0.0059 | 0.6064 | 0.6758 |
Schistosoma mansoni | hypothetical protein | 0.0059 | 0.6064 | 0.6064 |
Schistosoma mansoni | thyroid hormone receptor | 0.0025 | 0.1252 | 0.1252 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.008 | 0.8972 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0025 | 0.1252 | 0.1252 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0059 | 0.6064 | 0.5 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0025 | 0.1252 | 0.1252 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0059 | 0.6064 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.002 | 0.0667 | 0.0667 |
Echinococcus granulosus | fmrfamide receptor | 0.002 | 0.0667 | 0.0743 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0059 | 0.6064 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.002 | 0.0667 | 0.0743 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0059 | 0.6064 | 0.5 |
Brugia malayi | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.008 | 0.8972 | 1 |
Schistosoma mansoni | amine GPCR | 0.002 | 0.0667 | 0.0667 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0025 | 0.1252 | 0.1396 |
Brugia malayi | Cytochrome P450 family protein | 0.0059 | 0.6064 | 0.6758 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.002 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | amine GPCR | 0.002 | 0.0667 | 0.0667 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.002 | 0.0667 | 0.0743 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0059 | 0.6064 | 0.5 |
Brugia malayi | follicle stimulating hormone receptor | 0.002 | 0.0667 | 0.0743 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0059 | 0.6064 | 0.5 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | g-protein coupled receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0059 | 0.6064 | 0.5 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.002 | 0.0667 | 0.0667 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0059 | 0.6064 | 0.5 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.002 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | amine GPCR | 0.002 | 0.0667 | 0.0667 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | adenoreceptor | 0.002 | 0.0667 | 0.0667 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0059 | 0.6064 | 0.5 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1252 | 0.1396 |
Echinococcus multilocularis | fmrfamide receptor | 0.002 | 0.0667 | 0.0743 |
Leishmania major | cytochrome p450-like protein | 0.0059 | 0.6064 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0059 | 0.6064 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0025 | 0.1252 | 0.1396 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0025 | 0.1252 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | Cytochrome P450 family protein | 0.0059 | 0.6064 | 0.6758 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | opsin-like receptor | 0.002 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0059 | 0.6064 | 0.5 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0667 | 0.0667 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0023 | 0.1028 | 0.1028 |
Brugia malayi | Dopamine receptor protein 1 | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0025 | 0.1252 | 0.1396 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0025 | 0.1252 | 0.1396 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0074 | 0.8236 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | Serotonin receptor | 0.002 | 0.0667 | 0.0743 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.002 | 0.0667 | 0.0743 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0059 | 0.6064 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0025 | 0.1252 | 1 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0025 | 0.1252 | 0.1396 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0025 | 0.1252 | 0.1252 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0025 | 0.1252 | 0.1396 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0023 | 0.1028 | 0.1145 |
Brugia malayi | G-protein coupled receptor | 0.002 | 0.0667 | 0.0743 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0059 | 0.6064 | 0.5 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.002 | 0.0667 | 0.0667 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0059 | 0.6064 | 0.5 |
Echinococcus multilocularis | 0.0059 | 0.6064 | 0.6758 | |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0025 | 0.1252 | 0.1396 |
Brugia malayi | neuropeptide F receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.002 | 0.0667 | 0.0743 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0059 | 0.6064 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0059 | 0.6064 | 0.5 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | neuropeptide s receptor | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | biogenic amine receptor | 0.002 | 0.0667 | 0.0667 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0667 | 0.0667 |
Echinococcus multilocularis | somatostatin receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | Melatonin receptor type 1A | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1252 | 0.1396 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.002 | 0.0667 | 0.0743 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0025 | 0.1252 | 0.1396 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0667 | 0.0667 |
Brugia malayi | Serotonin receptor | 0.002 | 0.0667 | 0.0743 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0059 | 0.6064 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0667 | 0.0667 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.002 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.008 | 0.8972 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | nuclear hormone receptor | 0.0025 | 0.1252 | 0.1396 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0059 | 0.6064 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0059 | 0.6064 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0025 | 0.1252 | 0.1252 |
Echinococcus granulosus | orexin receptor type 2 | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0667 | 0.0667 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0025 | 0.1252 | 0.1396 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0025 | 0.1252 | 0.1396 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0667 | 0.0667 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.002 | 0.0667 | 0.0667 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.002 | 0.0667 | 0.0667 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0025 | 0.1252 | 0.1396 |
Mycobacterium leprae | putative cytochrome p450 | 0.0059 | 0.6064 | 0.5 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.002 | 0.0667 | 0.0667 |
Schistosoma mansoni | biogenic amine receptor | 0.002 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | neuropeptide F receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | voltage gated potassium channel | 0.0023 | 0.1028 | 0.1145 |
Schistosoma mansoni | neuropeptide receptor | 0.002 | 0.0667 | 0.0667 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0025 | 0.1252 | 0.1252 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0059 | 0.6064 | 0.6758 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0025 | 0.1252 | 0.1396 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0025 | 0.1252 | 0.1396 |
Brugia malayi | ORL1-like opioid receptor | 0.002 | 0.0667 | 0.0743 |
Trypanosoma brucei | cytochrome P450, putative | 0.0059 | 0.6064 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | ecdysteroid receptor | 0.0025 | 0.1252 | 0.1396 |
Echinococcus multilocularis | allatostatin A receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0025 | 0.1252 | 0.1396 |
Brugia malayi | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | amine GPCR | 0.002 | 0.0667 | 0.0667 |
Brugia malayi | steroid hormone receptor | 0.0025 | 0.1252 | 0.1396 |
Echinococcus granulosus | neuropeptide Y receptor | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0025 | 0.1252 | 0.1396 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.7495 | 0.8354 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0025 | 0.1252 | 0.1396 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.002 | 0.0667 | 0.0743 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0059 | 0.6064 | 0.5 |
Echinococcus granulosus | neuropeptides capa receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.002 | 0.0667 | 0.0667 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0059 | 0.6064 | 0.5 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.002 | 0.0667 | 0.0667 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.002 | 0.0667 | 0.0667 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0023 | 0.1028 | 0.1028 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1252 | 0.1396 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.002 | 0.0667 | 0.0667 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.002 | 0.0667 | 0.0743 |
Onchocerca volvulus | 0.0025 | 0.1252 | 1 | |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0025 | 0.1252 | 0.1252 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0025 | 0.1252 | 0.1396 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0025 | 0.1252 | 0.1396 |
Echinococcus granulosus | g-protein coupled receptor | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1028 | 0.1145 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0025 | 0.1252 | 0.1396 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.002 | 0.0667 | 0.0667 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0059 | 0.6064 | 0.5 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0023 | 0.1028 | 0.1145 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0059 | 0.6064 | 0.6758 |
Echinococcus multilocularis | neuropeptide receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | g protein coupled receptor | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0025 | 0.1252 | 0.1396 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0025 | 0.1252 | 0.1396 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0025 | 0.1252 | 0.1396 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0059 | 0.6064 | 0.6758 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0059 | 0.6064 | 0.5 |
Echinococcus granulosus | allatostatin A receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | histamine h1 receptor | 0.002 | 0.0667 | 0.0667 |
Brugia malayi | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0059 | 0.6064 | 0.5 |
Echinococcus granulosus | g protein coupled receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | neuropeptide Y receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | neuropeptide receptor | 0.002 | 0.0667 | 0.0743 |
Leishmania major | cytochrome p450-like protein | 0.0059 | 0.6064 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0025 | 0.1252 | 0.1252 |
Schistosoma mansoni | coup transcription factor | 0.0025 | 0.1252 | 0.1252 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0025 | 0.1252 | 0.1396 |
Brugia malayi | larval opioid receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0023 | 0.1028 | 0.1145 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0059 | 0.6064 | 0.6758 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0025 | 0.1252 | 0.1396 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0059 | 0.6064 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0059 | 0.6064 | 0.5 |
Brugia malayi | cytochrome P450 | 0.0059 | 0.6064 | 0.6758 |
Brugia malayi | GnHR receptor homolog | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.002 | 0.0667 | 0.0743 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0059 | 0.6064 | 0.5 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | serotonin receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | neuropeptide s receptor | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0667 | 0.0667 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | Dopamine receptor | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | Dopamine receptor protein 2 | 0.002 | 0.0667 | 0.0743 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0074 | 0.8236 | 1 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.008 | 0.8972 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0025 | 0.1252 | 0.1252 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | neuropeptides capa receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0025 | 0.1252 | 0.1396 |
Schistosoma mansoni | nuclear hormone receptor | 0.0025 | 0.1252 | 0.1252 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | G protein-coupled receptor | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0667 | 0.0667 |
Brugia malayi | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | g protein coupled receptor | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.002 | 0.0667 | 0.0667 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.002 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0667 | 0.0667 |
Echinococcus multilocularis | g protein coupled receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | sex peptide receptor | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1252 | 0.1396 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1252 | 0.1396 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | TYRA-2 protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | neuropeptide receptor | 0.002 | 0.0667 | 0.0743 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0059 | 0.6064 | 0.5 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0023 | 0.1028 | 0.1145 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0025 | 0.1252 | 0.1396 |
Echinococcus multilocularis | fmrfamide receptor | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0025 | 0.1252 | 0.1396 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0059 | 0.6064 | 0.5 |
Echinococcus granulosus | g protein coupled receptor | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | cytochrome P450 | 0.0059 | 0.6064 | 0.6064 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0025 | 0.1252 | 1 |
Brugia malayi | G-protein coupled receptor | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | neuropeptide receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0025 | 0.1252 | 0.1396 |
Schistosoma mansoni | amine GPCR | 0.002 | 0.0667 | 0.0667 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0059 | 0.6064 | 0.5 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0025 | 0.1252 | 0.1396 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0025 | 0.1252 | 0.1396 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | neuropeptide receptor | 0.002 | 0.0667 | 0.0667 |
Schistosoma mansoni | biogenic amine receptor | 0.002 | 0.0667 | 0.0667 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | neuropeptide receptor | 0.002 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0667 | 0.0667 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.002 | 0.0667 | 0.0667 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0025 | 0.1252 | 0.1396 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0059 | 0.6064 | 0.5 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.002 | 0.0667 | 0.0667 |
Brugia malayi | RE15519p | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | g protein coupled receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.002 | 0.0667 | 0.0743 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0059 | 0.6064 | 0.5 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0025 | 0.1252 | 0.1396 |
Brugia malayi | Cytochrome P450 family protein | 0.0059 | 0.6064 | 0.6758 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0025 | 0.1252 | 0.1396 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0025 | 0.1252 | 0.1252 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0025 | 0.1252 | 0.1396 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0025 | 0.1252 | 0.1396 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0059 | 0.6064 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.002 | 0.0667 | 0.0743 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0059 | 0.6064 | 0.5 |
Leishmania major | cytochrome p450-like protein | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | orexin receptor type 2 | 0.002 | 0.0667 | 0.0743 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0025 | 0.1252 | 0.1396 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1252 | 0.1396 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.002 | 0.0667 | 0.0667 |
Schistosoma mansoni | opsin-like receptor | 0.002 | 0.0667 | 0.0667 |
Echinococcus granulosus | somatostatin receptor | 0.002 | 0.0667 | 0.0743 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1252 | 0.1396 |
Echinococcus granulosus | FTZ F1 alpha | 0.0025 | 0.1252 | 0.1396 |
Schistosoma mansoni | neuropeptide receptor | 0.002 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | cytochrome P450 | 0.0059 | 0.6064 | 0.6758 |
Schistosoma mansoni | myosin xvIII | 0.002 | 0.0667 | 0.0667 |
Schistosoma mansoni | opsin-like receptor | 0.002 | 0.0667 | 0.0667 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | sulfakinin receptor protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0025 | 0.1252 | 0.1396 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | AKH receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus granulosus | serotonin receptor | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | sex peptide receptor | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.002 | 0.0667 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1252 | 0.1396 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.002 | 0.0667 | 0.0667 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0025 | 0.1252 | 0.1252 |
Brugia malayi | nuclear receptor NHR-88 | 0.0025 | 0.1252 | 0.1396 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.002 | 0.0667 | 0.0743 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0025 | 0.1252 | 0.1396 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0025 | 0.1252 | 0.1396 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.002 | 0.0667 | 0.0743 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0087 | 1 | 1 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0059 | 0.6064 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.002 | 0.0667 | 0.0743 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0025 | 0.1252 | 0.1396 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0025 | 0.1252 | 0.1396 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0059 | 0.6064 | 0.6758 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0059 | 0.6064 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0667 | 0.0667 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0059 | 0.6064 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0667 | 0.0743 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 8 ug ml-1 | Antibacterial activity against Streptococcus mutans after 16 to 20 hrs | ChEMBL. | 17296741 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.