Detailed information for compound 423414

Basic information

Technical information
  • TDR Targets ID: 423414
  • Name: (2S)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl )phenyl]ethanamine
  • MW: 297.782 | Formula: C17H16ClN3
  • H donors: 2 H acceptors: 1 LogP: 3.24 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC[C@H](c1ccc(cc1)Cl)c1ccc(cc1)c1c[nH]nc1
  • InChi: 1S/C17H16ClN3/c18-16-7-5-14(6-8-16)17(9-19)13-3-1-12(2-4-13)15-10-20-21-11-15/h1-8,10-11,17H,9,19H2,(H,20,21)/t17-/m0/s1
  • InChiKey: HWVGILTYGZFGLR-KRWDZBQOSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • [(2S)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]ethyl]amine
  • GVO

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens v-akt murine thymoma viral oncogene homolog 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis rac serine:threonine kinase Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) AGC/RSK/P70 protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium vivax rac-beta serine/threonine protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus serine threonine protein kinase nrc Get druggable targets OG5_126635 All targets in OG5_126635
Toxoplasma gondii AGC kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma cruzi rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum ko:K07390 monothiol glutaredoxin, putative Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma congolense rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium knowlesi RAC-beta serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Neospora caninum Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1), related Get druggable targets OG5_126635 All targets in OG5_126635
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma cruzi rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) AGC/AKT protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium falciparum RAC-beta serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum RAC serine/threonine-protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma cruzi Protein kinase B Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit Get druggable targets OG5_126635 All targets in OG5_126635
Giardia lamblia Kinase, AGC PKA Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium berghei rac-beta serine/threonine protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma brucei rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus sodium:potassium dependent atpase beta subunit Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis Glutaredoxin protein 5 Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma brucei gambiense rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma mansoni serine/threonine-protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum ko:K08792 serum/glucocorticoid regulated kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus calcium:calmodulin dependent protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus Glutaredoxin protein 5 Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum ko:K04456 RAC serine/threonine-protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma mansoni serine/threonine-protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium yoelii kinase Akt/PKB-related Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum Sodium/potassium-transporting ATPase subunit beta-1, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Brugia malayi p70 ribosomal S6 kinase beta Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase 2, putative Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans likely protein kinase similar to S. cerevisiae YPK2 (YMR104C) Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0574 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0541 0.0541
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.005 0.0541 0.0541
Trypanosoma cruzi cyclin 6, putative 0.0119 0.5186 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0047 0.0343 0.0343
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.009 0.3199 0.3199
Onchocerca volvulus Protein ultraspiracle homolog 0.009 0.3199 0.6169
Echinococcus multilocularis cyclins 0.0062 0.1305 0.1305
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.009 0.3199 0.3199
Entamoeba histolytica cyclin family protein 0.0062 0.1305 0.1645
Brugia malayi Nuclear hormone receptor family member nhr-3 0.009 0.3199 0.3199
Plasmodium falciparum cyclin 0.0062 0.1305 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.009 0.3199 0.3199
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.009 0.3199 0.3199
Schistosoma mansoni coup transcription factor 0.009 0.3199 0.3199
Echinococcus multilocularis cyclin dependent kinase 5 0.005 0.0541 0.0541
Trichomonas vaginalis cyclin D, putative 0.0062 0.1305 0.1645
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.009 0.3199 0.3199
Echinococcus multilocularis FTZ F1 alpha 0.009 0.3199 0.3199
Loa Loa (eye worm) hypothetical protein 0.0119 0.5186 0.5186
Trichomonas vaginalis cyclins, putative 0.0119 0.5186 1
Brugia malayi steroid hormone receptor 0.009 0.3199 0.3199
Brugia malayi Nuclear hormone receptor-like 1 0.0047 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0119 0.5186 0.5186
Brugia malayi Nuclear hormone receptor-like 1 0.0047 0.0343 0.0343
Entamoeba histolytica cyclin family protein 0.0062 0.1305 0.1645
Brugia malayi Nuclear hormone receptor family member nhr-19 0.009 0.3199 0.3199
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.009 0.3199 0.3199
Echinococcus granulosus cyclin B 0.0119 0.5186 0.5186
Entamoeba histolytica cyclin, putative 0.0062 0.1305 0.1645
Loa Loa (eye worm) hypothetical protein 0.009 0.3199 0.3199
Echinococcus granulosus cyclin b3 0.0062 0.1305 0.1305
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0047 0.0343 0.0343
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.005 0.0541 0.0541
Loa Loa (eye worm) hypothetical protein 0.0047 0.0343 0.0343
Schistosoma mansoni nuclear hormone receptor 0.009 0.3199 0.3199
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0574 0.0071
Schistosoma mansoni thyroid hormone receptor 0.009 0.3199 0.3199
Loa Loa (eye worm) hypothetical protein 0.009 0.3199 0.3199
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0047 0.0343 0.0343
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.009 0.3199 0.3199
Loa Loa (eye worm) hypothetical protein 0.009 0.3199 0.3199
Echinococcus multilocularis cyclin dependent kinase 1 0.005 0.0541 0.0541
Brugia malayi Steroid receptor seven-up type 2 0.009 0.3199 0.3199
Echinococcus granulosus cyclins 0.0062 0.1305 0.1305
Loa Loa (eye worm) cyclin domain-containing protein 0.019 1 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0047 0.0343 0.0343
Trichomonas vaginalis cyclins, putative 0.0062 0.1305 0.1645
Loa Loa (eye worm) AGC/AKT protein kinase 0.0051 0.0574 0.0574
Echinococcus granulosus nuclear receptor 2DBD gamma 0.009 0.3199 0.3199
Echinococcus granulosus G2:mitotic specific cyclin B3 0.019 1 1
Echinococcus granulosus cyclin B3 1 0.0062 0.1305 0.1305
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.009 0.3199 0.3199
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.009 0.3199 0.3199
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.009 0.3199 0.3199
Brugia malayi Cyclin, N-terminal domain containing protein 0.0119 0.5186 0.5186
Giardia lamblia G2/mitotic-specific cyclin B 0.0119 0.5186 1
Trichomonas vaginalis cyclin B, putative 0.0062 0.1305 0.1645
Brugia malayi Nuclear hormone receptor family member nhr-49 0.009 0.3199 0.3199
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.005 0.0541 0.0541
Brugia malayi Nuclear hormone receptor family member nhr-19 0.009 0.3199 0.3199
Trichomonas vaginalis cyclin D, putative 0.0062 0.1305 0.1645
Entamoeba histolytica protein kinase, putative 0.0051 0.0574 0.0071
Loa Loa (eye worm) hypothetical protein 0.009 0.3199 0.3199
Echinococcus multilocularis cyclins 0.0062 0.1305 0.1305
Trypanosoma cruzi cyclin, putative 0.0119 0.5186 1
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0574 0.0071
Loa Loa (eye worm) hypothetical protein 0.009 0.3199 0.3199
Loa Loa (eye worm) hypothetical protein 0.0047 0.0343 0.0343
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.009 0.3199 0.3199
Echinococcus granulosus cyclin dependent kinase 0.005 0.0541 0.0541
Echinococcus multilocularis cyclins 0.0062 0.1305 0.1305
Entamoeba histolytica cyclin, putative 0.0119 0.5186 1
Trichomonas vaginalis cyclins, putative 0.0119 0.5186 1
Trichomonas vaginalis cyclin A, putative 0.0119 0.5186 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.009 0.3199 0.3199
Echinococcus multilocularis cyclin b3 0.0062 0.1305 0.1305
Schistosoma mansoni cyclin B3 0.019 1 1
Brugia malayi ecdysteroid receptor 0.009 0.3199 0.3199
Brugia malayi Nuclear hormone receptor family member nhr-40 0.009 0.3199 0.3199
Entamoeba histolytica protein kinase, putative 0.0051 0.0574 0.0071
Loa Loa (eye worm) hypothetical protein 0.0047 0.0343 0.0343
Trypanosoma cruzi cyclin, putative 0.0119 0.5186 1
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0574 0.0071
Onchocerca volvulus 0.0119 0.5186 1
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0051 0.0574 0.0574
Echinococcus multilocularis cyclins 0.0062 0.1305 0.1305
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0047 0.0343 0.0343
Echinococcus multilocularis thyroid hormone receptor alpha 0.009 0.3199 0.3199
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.005 0.0541 0.0541
Echinococcus multilocularis cyclin dependent kinase 1 0.005 0.0541 0.0541
Brugia malayi Nuclear hormone receptor family member nhr-41 0.009 0.3199 0.3199
Brugia malayi Nuclear hormone receptor family member nhr-25 0.009 0.3199 0.3199
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.019 1 1
Plasmodium vivax protein kinase Crk2 0.005 0.0541 0.5
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0541 0.0541
Echinococcus multilocularis cyclin B 0.0119 0.5186 0.5186
Brugia malayi Nuclear hormone receptor family member nhr-31 0.009 0.3199 0.3199
Loa Loa (eye worm) hypothetical protein 0.009 0.3199 0.3199
Giardia lamblia Hypothetical protein 0.0062 0.1305 0.1645
Leishmania major cyclin 0.0119 0.5186 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.009 0.3199 0.3199
Brugia malayi nuclear receptor RXR 0.0047 0.0343 0.0343
Brugia malayi nuclear receptor NHR-88 0.009 0.3199 0.3199
Brugia malayi Protein kinase domain containing protein 0.005 0.0541 0.0541
Schistosoma mansoni cyclin B 0.0119 0.5186 0.5186
Echinococcus granulosus ecdysone induced protein 78C 0.009 0.3199 0.3199
Echinococcus granulosus cyclin dependent kinase 1 0.005 0.0541 0.0541
Schistosoma mansoni retinoid-x-receptor (RXR) 0.009 0.3199 0.3199
Trichomonas vaginalis cyclin B3, putative 0.0062 0.1305 0.1645
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.009 0.3199 0.3199
Echinococcus granulosus retinoic acid receptor rxr beta a 0.009 0.3199 0.3199
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0574 0.0071
Loa Loa (eye worm) hypothetical protein 0.009 0.3199 0.3199
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.009 0.3199 0.3199
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.009 0.3199 0.3199
Echinococcus multilocularis cyclin dependent kinase 0.005 0.0541 0.0541
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0574 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.009 0.3199 0.3199
Brugia malayi nuclear hormone receptor 0.009 0.3199 0.3199
Echinococcus granulosus nuclear receptor 2DBD gamma 0.009 0.3199 0.3199
Echinococcus granulosus cyclins 0.0062 0.1305 0.1305
Brugia malayi cell division control protein 2 homolog 0.005 0.0541 0.0541
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.009 0.3199 0.3199
Onchocerca volvulus 0.009 0.3199 0.6169
Trichomonas vaginalis cyclin B, putative 0.0119 0.5186 1
Schistosoma mansoni cyclins 0.0062 0.1305 0.1305
Echinococcus multilocularis cyclins 0.0062 0.1305 0.1305
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.009 0.3199 0.3199
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0119 0.5186 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.009 0.3199 0.3199
Brugia malayi Nuclear hormone receptor family member nhr-25 0.009 0.3199 0.3199
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.009 0.3199 0.3199
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.009 0.3199 0.3199
Loa Loa (eye worm) hypothetical protein 0.0047 0.0343 0.0343
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0574 0.0071
Loa Loa (eye worm) hypothetical protein 0.009 0.3199 0.3199
Giardia lamblia Cyclin A 0.0062 0.1305 0.1645
Toxoplasma gondii AGC kinase 0.0051 0.0574 1
Trichomonas vaginalis cyclins, putative 0.0119 0.5186 1
Trichomonas vaginalis cyclin B, putative 0.0119 0.5186 1
Trypanosoma brucei rac serine-threonine kinase, putative 0.0051 0.0574 0.0071
Schistosoma mansoni RAR-like nuclear receptor 0.009 0.3199 0.3199
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.005 0.0541 0.8787
Echinococcus granulosus FTZ F1 alpha 0.009 0.3199 0.3199
Echinococcus multilocularis cyclins 0.0062 0.1305 0.1305
Brugia malayi p70 ribosomal S6 kinase beta 0.0051 0.0574 0.0574
Schistosoma mansoni retinoic acid receptor RXR 0.009 0.3199 0.3199
Echinococcus multilocularis cyclins 0.0062 0.1305 0.1305
Loa Loa (eye worm) hypothetical protein 0.0057 0.1024 0.1024
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.009 0.3199 0.3199
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.009 0.3199 0.3199
Loa Loa (eye worm) hypothetical protein 0.0049 0.048 0.048
Echinococcus granulosus cyclins 0.0062 0.1305 0.1305
Echinococcus multilocularis ecdysone induced protein 78C 0.009 0.3199 0.3199
Trypanosoma cruzi CYC2-like cyclin, putative 0.0119 0.5186 1
Trichomonas vaginalis cyclins, putative 0.0072 0.2029 0.3203
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.009 0.3199 0.6169
Onchocerca volvulus Bile acid receptor homolog 0.009 0.3199 0.6169
Loa Loa (eye worm) hypothetical protein 0.0047 0.0343 0.0343
Brugia malayi photoreceptor-specific nuclear receptor 0.009 0.3199 0.3199
Brugia malayi hypothetical protein 0.0047 0.0343 0.0343
Brugia malayi Protein kinase domain containing protein 0.0051 0.0574 0.0574
Entamoeba histolytica protein kinase, putative 0.0051 0.0574 0.0071
Echinococcus granulosus cyclin dependent kinase 5 0.005 0.0541 0.0541
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.009 0.3199 0.3199
Trichomonas vaginalis cyclin B, putative 0.0119 0.5186 1
Echinococcus granulosus cyclins 0.0062 0.1305 0.1305
Trypanosoma brucei mitotic cyclin 6 0.0119 0.5186 1
Brugia malayi hypothetical protein 0.0047 0.0343 0.0343
Echinococcus granulosus cyclins 0.0062 0.1305 0.1305
Brugia malayi Nuclear hormone receptor-like 1 0.009 0.3199 0.3199
Trichomonas vaginalis cyclins, putative 0.0119 0.5186 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.009 0.3199 0.3199
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.1305 0.1645
Trichomonas vaginalis cyclin B, putative 0.0119 0.5186 1
Schistosoma mansoni thyroid hormone receptor 0.009 0.3199 0.3199
Loa Loa (eye worm) steroid hormone receptor 0.009 0.3199 0.3199
Brugia malayi Cyclin, N-terminal domain containing protein 0.0119 0.5186 0.5186
Echinococcus multilocularis cyclin B3 1 0.0062 0.1305 0.1305
Brugia malayi Nuclear hormone receptor family member nhr-14 0.009 0.3199 0.3199

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.28 uM Inhibition of PKBbeta by radiometric filter binding assay ChEMBL. 17451234
IC50 (binding) = 0.28 uM Inhibition of PKBbeta by radiometric filter binding assay ChEMBL. 17451234

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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