Detailed information for compound 42368

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 389.876 | Formula: C20H24ClN3O3
  • H donors: 2 H acceptors: 1 LogP: 2.34 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(Cl)c(cc1C(=O)NCC1OCCN(C1)Cc1ccccc1)N
  • InChi: 1S/C20H24ClN3O3/c1-26-19-10-17(21)18(22)9-16(19)20(25)23-11-15-13-24(7-8-27-15)12-14-5-3-2-4-6-14/h2-6,9-10,15H,7-8,11-13,22H2,1H3,(H,23,25)
  • InChiKey: LYYSNLKOMKPMQS-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis set domain proteins, putative 0.0231 0.2048 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0241 0.024
Onchocerca volvulus 0.1069 1 1
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0095 0.0081
Echinococcus granulosus expressed conserved protein 0.009 0.0707 0.0706
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0013 0.0143
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0122 0.4201
Loa Loa (eye worm) esterase D 0.0035 0.0179 0.0166
Schistosoma mansoni lipoxygenase 0.0108 0.0874 0.0873
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus granulosus somatostatin receptor 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0288 0.0287
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.1069 1 1
Brugia malayi hypothetical protein 0.1069 1 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.1069 1 1
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0017 0.0013 0.0016
Brugia malayi hypothetical protein 0.0119 0.0979 0.0979
Brugia malayi 6-phosphofructokinase 0.0106 0.0858 0.0858
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0126 0.0125
Schistosoma mansoni hypothetical protein 0.004 0.0227 0.0226
Echinococcus granulosus thyrotropin releasing hormone receptor 0.1069 1 1
Mycobacterium ulcerans secreted antigen 85-B FbpB 0.0035 0.0179 0.0234
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0308 0.0307
Echinococcus granulosus tm gpcr rhodopsin 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Brugia malayi hypothetical protein 0.1069 1 1
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.0858 0.0857
Schistosoma mansoni opsin-like receptor 0.1069 1 1
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.0858 0.0857
Echinococcus multilocularis chromobox protein 1 0.0068 0.0496 0.0495
Leishmania major trypanothione reductase 0.0046 0.0288 0.3347
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.1069 1 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.0962 0.126
Mycobacterium tuberculosis Conserved protein 0.0035 0.0179 0.0234
Loa Loa (eye worm) hypothetical protein 0.0025 0.0083 0.007
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus multilocularis RUN 0.0039 0.0215 0.0214
Onchocerca volvulus 0.0231 0.2048 0.194
Echinococcus granulosus serotonin receptor 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Schistosoma mansoni loxhd1 0.0039 0.0215 0.0214
Echinococcus granulosus allatostatin A receptor 0.1069 1 1
Mycobacterium tuberculosis Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) 0.0819 0.7629 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.0962 0.126
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1069 1 1
Schistosoma mansoni amine GPCR 0.1069 1 1
Plasmodium vivax glutathione reductase, putative 0.0046 0.0288 1
Brugia malayi RE15519p 0.1069 1 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.1069 1 1
Schistosoma mansoni neuropeptide F-like receptor 0.1069 1 1
Brugia malayi glutathione reductase 0.0046 0.0288 0.0288
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0122 0.0589
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0083 0.0956
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0126 0.0125
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0017 0.0013 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0017 0.0013 0.0016
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0122 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0241 0.0228
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0368 0.0355
Echinococcus granulosus g protein coupled receptor 0.1069 1 1
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0017 0.0013 0.0016
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0858 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0288 0.0376
Schistosoma mansoni neuropeptide f receptor 76f 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Schistosoma mansoni rab6-interacting 0.0039 0.0215 0.0214
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0858 0.4187
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.1069 1 1
Brugia malayi Serotonin receptor 0.1069 1 1
Schistosoma mansoni opsin-like receptor 0.1069 1 1
Mycobacterium tuberculosis Probable reductase 0.0105 0.085 0.1113
Schistosoma mansoni biogenic amine (5HT) receptor 0.1069 1 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0322 0.0309
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.0858 1
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0083 0.199
Loa Loa (eye worm) hypothetical protein 0.0039 0.0215 0.0202
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0322 0.1568
Schistosoma mansoni biogenic amine receptor 0.1069 1 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0215 0.0214
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0083 0.0956
Echinococcus granulosus rhodopsin orphan GPCR 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.1069 1 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.0962 0.126
Schistosoma mansoni amine GPCR 0.1069 1 1
Onchocerca volvulus 0.1069 1 1
Brugia malayi Cytochrome P450 family protein 0.0026 0.0095 0.0095
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0297 0.0297
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0239 0.1163
Onchocerca volvulus 0.1069 1 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.085 0.1113
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.1069 1 1
Echinococcus granulosus tumor protein p63 0.033 0.2986 0.2985
Mycobacterium ulcerans hypothetical protein 0.0035 0.0179 0.0234
Loa Loa (eye worm) hypothetical protein 0.031 0.2794 0.2784
Loa Loa (eye worm) melatonin receptor type 1A 0.1069 1 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0792 0.7376 0.7376
Schistosoma mansoni alpha-1 adrenergic receptor 0.1069 1 1
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0017 0.0013 0.0016
Echinococcus granulosus RUN 0.0039 0.0215 0.0214
Schistosoma mansoni growth hormone secretagogue receptor 0.1069 1 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0122 0.4201
Echinococcus multilocularis neuropeptide FF receptor 2 0.1069 1 1
Brugia malayi larval opioid receptor 0.1069 1 1
Echinococcus multilocularis fmrfamide receptor 0.1069 1 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.085 0.1113
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0013 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0322 0.0321
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0017 0.0013 0.0016
Schistosoma mansoni jumonji/arid domain-containing protein 0.0057 0.0395 0.0394
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0288 0.3347
Loa Loa (eye worm) G-protein coupled receptor 0.1069 1 1
Schistosoma mansoni hypothetical protein 0.1069 1 1
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0017 0.0013 0.0016
Brugia malayi Pre-SET motif family protein 0.0029 0.0126 0.0126
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.1069 1 1
Echinococcus multilocularis CREB binding protein 0.0016 0.0003 0.0002
Schistosoma mansoni neuropeptide receptor 0.1069 1 1
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0322 0.0321
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0017 0.0013 0.0016
Loa Loa (eye worm) neuropeptide F receptor 0.1069 1 1
Onchocerca volvulus 0.1069 1 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.1069 1 1
Schistosoma mansoni histamine h1 receptor 0.1069 1 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0322 0.0321
Onchocerca volvulus 0.0039 0.0215 0.0083
Onchocerca volvulus 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Onchocerca volvulus 0.004 0.0232 0.01
Schistosoma mansoni hypothetical protein 0.004 0.0227 0.0226
Loa Loa (eye worm) hypothetical protein 0.0051 0.0329 0.0317
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0453 0.0593
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0322 0.3745
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0017 0.0013 0.0016
Echinococcus granulosus biogenic amine 5HT receptor 0.1069 1 1
Brugia malayi TAZ zinc finger family protein 0.0099 0.079 0.079
Schistosoma mansoni opsin-like receptor 0.1069 1 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.1069 1 1
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0095 0.1093
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0288 0.0275
Schistosoma mansoni survival motor neuron protein 0.0047 0.0297 0.0296
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0858 0.4187
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0858 0.4187
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Loa Loa (eye worm) G-protein coupled receptor 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0215 0.0202
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0288 1
Echinococcus granulosus neuropeptide receptor A26 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Onchocerca volvulus 0.1069 1 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0308 0.0295
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0122 0.0589
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0858 0.0846
Brugia malayi GnHR receptor homolog 0.1069 1 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0322 0.3745
Brugia malayi hypothetical protein 0.1069 1 1
Schistosoma mansoni hypothetical protein 0.0017 0.0013 0.0012
Onchocerca volvulus 0.1069 1 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0064 0.0453 0.528
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Schistosoma mansoni hypothetical protein 0.0047 0.0297 0.0296
Echinococcus granulosus rhodopsin orphan GPCR 0.1069 1 1
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0017 0.0013 0.0016
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.1069 1 1
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.0858 0.1123
Echinococcus granulosus orexin receptor type 2 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0017 0.0013 0.0016
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0122 0.4201
Mycobacterium ulcerans hypothetical protein 0.0035 0.0179 0.0234
Schistosoma mansoni adenoreceptor 0.1069 1 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0108 0.0874 0.0873
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0322 0.0321
Brugia malayi ORL1-like opioid receptor 0.1069 1 1
Schistosoma mansoni hypothetical protein 0.1069 1 1
Echinococcus granulosus g protein coupled receptor 0.1069 1 1
Brugia malayi G protein-coupled receptor F59B2.13 0.1069 1 1
Brugia malayi cytochrome P450 0.0017 0.0013 0.0013
Echinococcus granulosus rhodopsin orphan GPCR 0.1069 1 1
Brugia malayi Melatonin receptor type 1A 0.1069 1 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0413 0.054
Brugia malayi sulfakinin receptor protein 0.1069 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.1069 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1069 1 1
Brugia malayi jmjC domain containing protein 0.0057 0.0395 0.0395
Onchocerca volvulus 0.1069 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.1069 1 1
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0083 0.2855
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0413 0.4803
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0288 0.0287
Onchocerca volvulus 0.1069 1 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0413 0.0412
Echinococcus granulosus peptide allatostatin:somatostatin 0.1069 1 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0126 0.0125
Echinococcus multilocularis neuropeptide s receptor 0.1069 1 1
Echinococcus multilocularis CREB binding protein 0.0068 0.0495 0.0494
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1069 1 1
Schistosoma mansoni biogenic amine receptor 0.1069 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1069 1 1
Echinococcus granulosus lysine specific demethylase 5A 0.0057 0.0395 0.0394
Schistosoma mansoni amine GPCR 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Mycobacterium ulcerans secreted Mpt51/Mpb51 antigen protein FbpD 0.0035 0.0179 0.0234
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0239 0.0107
Echinococcus granulosus fmrfamide receptor 0.1069 1 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0215 0.0214
Mycobacterium leprae SECRETED ANTIGEN 85-C FBPC (85C) (ANTIGEN 85 COMPLEX C) (AG58C) (MYCOLYL TRANSFERASE 85C) (FIBRONECTIN-BINDING PROTEIN C) 0.0819 0.7629 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.1781 0.177
Schistosoma mansoni chromobox protein 0.0068 0.0496 0.0495
Mycobacterium tuberculosis Probable conserved exported protein 0.0035 0.0179 0.0234
Loa Loa (eye worm) phosphofructokinase 0.0106 0.0858 0.0846
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0095 0.0123
Brugia malayi G-protein coupled receptor 0.1069 1 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0083 0.0956
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.1069 1 1
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0858 0.0857
Onchocerca volvulus 0.1069 1 1
Brugia malayi G protein-coupled receptor 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0291 0.0278
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0122 0.0589
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0017 0.0013 0.0016
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0017 0.0013 0.0016
Brugia malayi hypothetical protein 0.0039 0.0215 0.0215
Echinococcus multilocularis neuropeptide Y receptor 0.1069 1 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.1069 1 1
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0215 0.0202
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.085 0.1113
Echinococcus multilocularis G protein coupled receptor 139 0.1069 1 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0858 0.0846
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0215 0.0214
Echinococcus multilocularis chromobox protein 1 0.0068 0.0496 0.0495
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0017 0.0013 0.0016
Onchocerca volvulus 0.1069 1 1
Mycobacterium tuberculosis Secreted antigen 85-a FbpA (mycolyl transferase 85A) (fibronectin-binding protein A) (antigen 85 complex A) 0.0035 0.0179 0.0234
Trypanosoma brucei trypanothione reductase 0.0046 0.0288 0.3347
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0095 0.0081
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0413 0.054
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.085 0.1113
Entamoeba histolytica endo-1,4-beta-xylanase, putative 0.0035 0.0179 0.0786
Onchocerca volvulus 0.1069 1 1
Echinococcus multilocularis neuropeptide receptor 0.1069 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.1069 1 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0777 0.0776
Schistosoma mansoni neuropeptide receptor 0.1069 1 1
Loa Loa (eye worm) neuropeptide F receptor 0.1069 1 1
Schistosoma mansoni hypothetical protein 0.004 0.0227 0.0226
Echinococcus multilocularis rhodopsin orphan GPCR 0.1069 1 1
Brugia malayi hypothetical protein 0.0025 0.0083 0.0083
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0346 0.0333
Brugia malayi G-protein coupled receptor 0.1069 1 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.1069 1 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.2044 0.2043
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0322 0.3745
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Brugia malayi Cytochrome P450 family protein 0.0017 0.0013 0.0013
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1069 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0241 0.1173
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0017 0.0013 0.0016
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0241 0.0228
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1069 1 1
Brugia malayi Serotonin receptor 0.1069 1 1
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0017 0.0013 0.0016
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Schistosoma mansoni chromobox protein 0.0068 0.0496 0.0495
Brugia malayi putative neuropeptide receptor NPR1 0.1069 1 1
Echinococcus granulosus 7tm_1 domain containing protein 0.1069 1 1
Echinococcus multilocularis somatostatin receptor 0.1069 1 1
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0099 0.079 0.0789
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1069 1 1
Schistosoma mansoni neuropeptide receptor 0.1069 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.1069 1 1
Echinococcus multilocularis neuropeptides capa receptor 0.1069 1 1
Echinococcus multilocularis protein dispatched 1 0.0047 0.0297 0.0296
Schistosoma mansoni biogenic amine (dopamine) receptor 0.1069 1 1
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0858 1
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0413 0.0412
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0095 0.1093
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.2044 0.2043
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0122 0.0589
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.1069 1 1
Schistosoma mansoni patched 1 0.0041 0.0241 0.024
Echinococcus multilocularis expressed conserved protein 0.009 0.0707 0.0706
Echinococcus granulosus hypothetical protein 0.1069 1 1
Brugia malayi phosphofructokinase 0.0106 0.0858 0.0858
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0241 0.024
Onchocerca volvulus 0.1069 1 1
Brugia malayi hypothetical protein 0.0039 0.0215 0.0215
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0017 0.0013 0.0016
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.1069 1 1
Onchocerca volvulus 0.1069 1 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0122 0.0589
Echinococcus granulosus sex peptide receptor 0.1069 1 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.1069 1 1
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0017 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Brugia malayi hypothetical protein 0.1069 1 1
Echinococcus multilocularis neuropeptide receptor A26 0.1069 1 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0215 0.0214
Brugia malayi gonadotropin-releasing hormone receptor 2 0.1069 1 1
Plasmodium falciparum glutathione reductase 0.0046 0.0288 1
Schistosoma mansoni neuropeptide receptor 0.1069 1 1
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0017 0.0013 0.0016
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1069 1 1
Schistosoma mansoni amine GPCR 0.1069 1 1
Brugia malayi Dopamine receptor 0.1069 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0106 0.0511
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.1069 1 1
Brugia malayi Dopamine receptor protein 1 0.1069 1 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0001 0.5
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0322 0.1568
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0763 0.8709
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0322 0.3745
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.1069 1 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0057 0.0395 0.0394
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0017 0.0013 0.0016
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0413 1
Echinococcus granulosus g protein coupled receptor 0.1069 1 1
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0017 0.0013 0.0016
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0858 0.0857
Onchocerca volvulus 0.0047 0.0297 0.0166
Echinococcus multilocularis rhodopsin orphan GPCR 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0322 0.1568
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1069 1 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0322 0.3745
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0057 0.0395 0.0394
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0017 0.0013 0.0016
Brugia malayi neuropeptide F receptor 0.1069 1 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0122 0.0589
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0322 0.3745
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0064 0.0453 0.0452
Echinococcus multilocularis neuropeptides capa receptor 0.1069 1 1
Echinococcus multilocularis CREB binding protein 0.0016 0.0003 0.0002
Echinococcus granulosus G protein coupled receptor 139 0.1069 1 1
Echinococcus granulosus CREB binding protein 0.0099 0.079 0.0789
Echinococcus granulosus neuropeptide receptor 0.1069 1 1
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0496 0.2417
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1069 1 1
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0017 0.0013 0.0016
Echinococcus multilocularis neuropeptide receptor 0.1069 1 1
Schistosoma mansoni biogenic amine receptor 0.1069 1 1
Loa Loa (eye worm) glutathione reductase 0.0046 0.0288 0.0275
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.0858 0.1109
Brugia malayi hypothetical protein 0.1069 1 1
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0241 0.024
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0215 0.7463
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0017 0.0013 0.0016
Echinococcus multilocularis neuropeptide Y receptor 0.1069 1 1
Brugia malayi chromobox protein homolog 3 0.0038 0.0211 0.0211
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.1155 0.1154
Toxoplasma gondii thioredoxin reductase 0.0046 0.0288 0.697
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0017 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0231 0.2044 0.2033
Onchocerca volvulus 0.0039 0.0215 0.0083
Brugia malayi Thioredoxin reductase 0.0046 0.0288 0.0288
Leishmania major hypothetical protein, conserved 0.0025 0.0083 0.0956
Echinococcus granulosus rhodopsin orphan GPCR 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0126 0.0113
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0413 0.0412
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.085 0.1113
Leishmania major cytochrome p450-like protein 0.0017 0.0013 0.0143
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0108 0.0874 0.0873
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0017 0.0013 0.0016
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0017 0.0013 0.0016
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0122 1
Mycobacterium tuberculosis Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-bind 0.0035 0.0179 0.0234
Onchocerca volvulus Neuropeptide F receptor homolog 0.1069 1 1
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0858 0.4187
Onchocerca volvulus 0.1069 1 1
Echinococcus multilocularis allatostatin A receptor 0.1069 1 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0122 0.1406
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0122 0.2928
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0453 0.0452
Loa Loa (eye worm) jmjC domain-containing protein 0.0057 0.0395 0.0382
Echinococcus multilocularis g-protein coupled receptor 0.1069 1 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.1069 1 1
Brugia malayi Doublecortin family protein 0.0039 0.0215 0.0215
Echinococcus multilocularis S formylglutathione hydrolase 0.0035 0.0179 0.0178
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0017 0.0013 0.0016
Schistosoma mansoni polycystin 1-related 0.0039 0.0215 0.0214
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.0858 0.1123
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Brugia malayi Dopamine receptor protein 2 0.1069 1 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0126 0.0125
Brugia malayi hypothetical protein 0.1069 1 1
Brugia malayi follicle stimulating hormone receptor 0.1069 1 1
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0858 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1069 1 1
Schistosoma mansoni hypothetical protein 0.004 0.0227 0.0226
Brugia malayi AKH receptor 0.1069 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1069 1 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0095 0.0081
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0322 0.3745
Echinococcus multilocularis lysine specific demethylase 5A 0.0057 0.0395 0.0394
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0215 0.0214
Echinococcus multilocularis tumor protein p63 0.033 0.2986 0.2985
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0413 0.054
Schistosoma mansoni cytochrome P450 0.0017 0.0013 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0017 0.0013 0.0016
Schistosoma mansoni hypothetical protein 0.0039 0.0215 0.0214
Echinococcus multilocularis protein patched 0.0041 0.0241 0.024
Schistosoma mansoni hypothetical protein 0.1069 1 1
Schistosoma mansoni hypothetical protein 0.1069 1 1
Mycobacterium tuberculosis Possible conserved membrane protein 0.0035 0.0179 0.0234
Brugia malayi hypothetical protein 0.1069 1 1
Mycobacterium ulcerans secreted antigen 85-C FbpC 0.0819 0.7629 1
Echinococcus granulosus chromobox protein 1 0.0068 0.0496 0.0495
Echinococcus granulosus dro:myosuppressin receptor 0.1069 1 1
Echinococcus multilocularis g protein coupled receptor 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.1069 1 1
Brugia malayi Pre-SET motif family protein 0.0203 0.1781 0.1781
Echinococcus granulosus tachykinin peptides receptor 99D 0.1069 1 1
Brugia malayi Heterochromatin protein 1 0.0068 0.0496 0.0496
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.1069 1 1
Brugia malayi putative neuropeptide receptor 0.1069 1 1
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0239 0.1163
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.1069 1 1
Mycobacterium leprae SECRETED ANTIGEN 85-B FBPB (85B) (ANTIGEN 85 COMPLEX B) (MYCOLYL TRANSFERASE 85B) (FIBRONECTIN-BINDING PROTEIN B) (EXTRACELLULAR 0.0035 0.0179 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0211 0.1028
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0122 0.2928
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0858 1
Schistosoma mansoni lipoxygenase 0.0039 0.0215 0.0214
Brugia malayi hypothetical protein 0.1069 1 1
Schistosoma mansoni jumonji domain containing protein 0.0057 0.0395 0.0394
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0322 0.1568
Schistosoma mansoni amine GPCR 0.1069 1 1
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0017 0.0013 0.0143
Echinococcus multilocularis sex peptide receptor 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0126 0.0125
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.085 0.1099
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0017 0.0013 0.0016
Echinococcus multilocularis CREB binding protein 0.0016 0.0003 0.0002
Brugia malayi CHE-14 protein 0.0041 0.0241 0.0241
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0496 0.0483
Schistosoma mansoni jumonji/arid domain-containing protein 0.0057 0.0395 0.0394
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Mycobacterium ulcerans hypothetical protein 0.0035 0.0179 0.0234
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0083 0.2855
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0017 0.0013 0.0016
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.1069 1 1
Echinococcus multilocularis 0.0017 0.0013 0.0012
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0017 0.0013 0.0016
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0322 0.0321
Echinococcus multilocularis dro:myosuppressin receptor 0.1069 1 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.1069 1 1
Echinococcus granulosus CREB binding protein 0.0016 0.0003 0.0002
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.0962 0.1246
Echinococcus multilocularis serotonin receptor 0.1069 1 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.1069 1 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.1069 1 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.1069 1 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1069 1 1
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0017 0.0013 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0211 0.1028
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.1069 1 1
Echinococcus granulosus chromobox protein 1 0.0068 0.0496 0.0495
Echinococcus multilocularis rhodopsin orphan GPCR 0.1069 1 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.1069 1 1
Plasmodium vivax SET domain protein, putative 0.0029 0.0126 0.4358
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0763 0.0762
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0858 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.1069 1 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.1069 1 1
Mycobacterium ulcerans hypothetical protein 0.0035 0.0179 0.0234
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0322 1
Onchocerca volvulus 0.1069 1 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0126 0.3037
Loa Loa (eye worm) hypothetical protein 0.0096 0.0763 0.0751
Echinococcus multilocularis g protein coupled receptor 0.1069 1 1
Echinococcus granulosus neuropeptide FF receptor 2 0.1069 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.1069 1 1
Brugia malayi hypothetical protein 0.0231 0.2044 0.2044
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0215 0.7463
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0017 0.0013 0.0016
Schistosoma mansoni biogenic amine (dopamine) receptor 0.1069 1 1
Echinococcus granulosus CREB binding protein 0.0016 0.0003 0.0002
Echinococcus multilocularis orexin receptor type 2 0.1069 1 1
Echinococcus granulosus neuropeptide Y receptor 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0017 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0453 0.0452
Mycobacterium tuberculosis Secreted antigen 85-B FbpB (85B) (antigen 85 complex B) (mycolyl transferase 85B) (fibronectin-binding protein B) (extracellular 0.0035 0.0179 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0106 0.0511
Schistosoma mansoni neuropeptide F-like receptor 0.1069 1 1
Brugia malayi MAP kinase sur-1 0.005 0.0322 0.0322
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0322 0.7797
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0122 0.2928
Schistosoma mansoni myosin xvIII 0.1069 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.1069 1 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0001 0.5
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0122 0.4201
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.1155 0.1154
Echinococcus multilocularis rhodopsin orphan GPCR 0.1069 1 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.1069 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.1069 1 1
Brugia malayi jmjC domain containing protein 0.0057 0.0395 0.0395
Echinococcus granulosus CREB binding protein 0.0061 0.043 0.0429
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0133 0.012
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0453 0.0453
Echinococcus multilocularis g protein coupled receptor 0.1069 1 1
Brugia malayi hypothetical protein 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0035 0.0179 0.0234
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0017 0.0013 0.0016
Trypanosoma brucei protein kinase, putative 0.005 0.0322 0.3745
Echinococcus granulosus g-protein coupled receptor 0.1069 1 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0013 0.0143
Brugia malayi Cytochrome P450 family protein 0.0026 0.0095 0.0095
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0017 0.0013 0.0016
Mycobacterium leprae Secreted antigen 85A FbpA (mycolyl transferase 85A) (fibronectin-binding protein A) (antigen 85 complex A) 0.0035 0.0179 0.0218
Echinococcus granulosus neuropeptides capa receptor 0.1069 1 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0211 0.0079
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0215 0.0214
Echinococcus granulosus neuropeptide s receptor 0.1069 1 1
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0496 0.2417
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0122 0.3755
Leishmania major cytochrome p450-like protein 0.0026 0.0095 0.1093
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0126 0.0125
Loa Loa (eye worm) CBP-B 0.0069 0.0503 0.049
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0413 0.054
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0198
Leishmania major cytochrome p450-like protein 0.0017 0.0013 0.0143
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.1069 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0064 0.0453 0.0593
Echinococcus granulosus neuropeptide receptor 0.1069 1 1
Echinococcus multilocularis fmrfamide receptor 0.1069 1 1
Mycobacterium ulcerans secreted antigen 85-A FbpA 0.0035 0.0179 0.0234
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.0858 1
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0017 0.0013 0.0016
Brugia malayi neuropeptide F receptor 0.1069 1 1
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0017 0.0013 0.0016
Brugia malayi 6-phosphofructokinase 0.0106 0.0858 0.0858
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0017 0.0013 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0122 0.0589
Schistosoma mansoni CREB-binding protein 2 0.0099 0.079 0.0789
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0116 0.0115
Toxoplasma gondii cytochrome p450 superfamily protein 0.0017 0.0013 0.0298
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.1069 1 1
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0017 0.0013 0.0143
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0453 0.0593
Onchocerca volvulus 0.0048 0.0308 0.0177
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0413 0.0412
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0763 0.0762
Echinococcus granulosus neuropeptide Y receptor 0.1069 1 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.004 0.0232 0.0231
Brugia malayi Cytochrome P450 family protein 0.0055 0.0368 0.0368
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0083 0.2855
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0095 0.1093
Onchocerca volvulus 0.1069 1 1
Schistosoma mansoni rab6-interacting 0.0039 0.0215 0.0214
Echinococcus granulosus S formylglutathione hydrolase 0.0035 0.0179 0.0178
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.1069 1 1
Loa Loa (eye worm) hypothetical protein 0.1069 1 1
Loa Loa (eye worm) TYRA-2 protein 0.1069 1 1
Echinococcus multilocularis serotonin receptor 0.1069 1 1
Echinococcus granulosus neuropeptides capa receptor 0.1069 1 1
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0017 0.0013 0.0143
Schistosoma mansoni biogenic amine (5HT) receptor 0.1069 1 1
Plasmodium falciparum thioredoxin reductase 0.0046 0.0288 1
Brugia malayi Esterase D 0.0035 0.0179 0.0179

Activities

Activity type Activity value Assay description Source Reference
GE (functional) = 10 % Evaluated for the effects on the gastric emptying rates of phenol red semisolid meal through the stomach in rats, at a dose of 2.0 mg/Kg administered perorally. ChEMBL. 2139471

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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