Detailed information for compound 424369

Basic information

Technical information
  • TDR Targets ID: 424369
  • Name: 3-heptoxybenzoate
  • MW: 235.299 | Formula: C14H19O3-
  • H donors: 0 H acceptors: 2 LogP: 4.94 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCOc1cccc(c1)C(=O)[O-]
  • InChi: 1S/C14H20O3/c1-2-3-4-5-6-10-17-13-9-7-8-12(11-13)14(15)16/h7-9,11H,2-6,10H2,1H3,(H,15,16)/p-1
  • InChiKey: FOFZVIUYGPBWLV-UHFFFAOYSA-M  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0173 0.0173
Toxoplasma gondii non-specific serine/threonine protein kinase 0.001 0.0014 0.0079
Plasmodium vivax serine/threonine protein phosphatase 2B catalytic subunit A, putative 0.0322 0.174 0.1734
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.0002
Schistosoma mansoni apoferritin-2 0.0009 0.0008 0.0008
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0147 0.0147
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Brugia malayi Cathepsin L-like precursor 0.0018 0.0058 0.0058
Brugia malayi splicing factor 3B subunit 3 0.0029 0.012 0.012
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0072 0.0072
Plasmodium vivax heat shock protein 90, putative 0.0014 0.0036 0.0026
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0025
Schistosoma mansoni nuclear receptor 0.0039 0.0173 0.0173
Brugia malayi nuclear receptor RXR 0.0043 0.0199 0.0199
Echinococcus multilocularis endoplasmin 0.0027 0.0108 0.0108
Brugia malayi Hsp90 protein 0.0014 0.0036 0.0036
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0044 0.0044
Brugia malayi nuclear receptor RXR 0.0039 0.0173 0.0173
Mycobacterium ulcerans lipase LipD 0.0078 0.0391 0.0391
Brugia malayi Papain family cysteine protease containing protein 0.0009 0.001 0.001
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0256 0.1376 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0218 0.0211
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0058 0.008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0749 0.0749
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0082 0.0082
Onchocerca volvulus 0.0018 0.0058 0.008
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0185 0.0185
Onchocerca volvulus 0.0029 0.012 0.0233
Trypanosoma cruzi cysteine protease, putative 0.0009 0.001 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0484 0.0484
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0058 0.005
Brugia malayi nuclear hormone receptor family member odr-7 0.0039 0.0173 0.0173
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0082 0.0413 0.0413
Schistosoma mansoni hypothetical protein 0.0054 0.0257 0.0257
Plasmodium vivax heat shock protein 86, putative 0.0034 0.0147 0.0137
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0218 0.0219
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0058 0.008
Schistosoma mansoni endoplasmin 0.0034 0.0147 0.0147
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0196 0.0196
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0095 0.0484 0.0484
Loa Loa (eye worm) hypothetical protein 0.0095 0.0484 0.0484
Loa Loa (eye worm) hypothetical protein 0.0029 0.012 0.012
Trichomonas vaginalis fk506-binding protein, putative 0.1813 0.9986 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0196 0.0196
Loa Loa (eye worm) agrin synaptic family protein 0.002 0.0069 0.0069
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0256 0.1376 0.7907
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.0435 0.2363 0.2363
Loa Loa (eye worm) hypothetical protein 0.002 0.0072 0.0072
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0009 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0046 0.0038
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0346 0.0346
Mycobacterium tuberculosis Probable esterase LipL 0.0078 0.0391 0.1438
Leishmania major heat shock protein, putative 0.0014 0.0036 0.0036
Mycobacterium tuberculosis Probable lipase LipD 0.0078 0.0391 0.1438
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0078 0.0391 0.0391
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0031 0.0031
Brugia malayi hypothetical protein 0.0043 0.0199 0.0199
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Echinococcus multilocularis beta LACTamase domain containing family member 0.0078 0.0391 0.0391
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0498 0.2715 1
Loa Loa (eye worm) hypothetical protein 0.0322 0.174 0.1743
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0256 0.1376 0.1378
Trypanosoma cruzi cruzipain precursor, putative 0.0068 0.0334 0.0335
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0072 0.0072
Onchocerca volvulus 0.0029 0.012 0.0233
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0043 0.0043
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0218 0.0218
Echinococcus granulosus axis inhibition protein axin 0.002 0.0072 0.0072
Echinococcus multilocularis agrin 0.002 0.0069 0.0069
Onchocerca volvulus 0.0748 0.4097 1
Echinococcus multilocularis heat shock protein 0.0034 0.0147 0.0147
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0072 0.0072
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0143 0.0749 0.075
Loa Loa (eye worm) DR-78 0.0039 0.0173 0.0173
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.1813 0.9986 1
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0256 0.1376 0.1378
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0334 0.0335
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0118 0.0118
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0027 0.0108 0.0399
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0147 0.0147
Trypanosoma brucei DNA polymerase IV, putative 0.0036 0.0158 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0046 0.0038
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0058 0.0058
Echinococcus multilocularis FTZ F1 alpha 0.0082 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0199
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0391 0.0391
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0484 0.0484
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0078 0.0391 0.1438
Trypanosoma brucei heat shock protein, putative 0.0034 0.0147 0.0147
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.1813 0.9986 1
Mycobacterium tuberculosis Probable hydrolase 0.0078 0.0391 0.1438
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.018 0.0173
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0043 0.0199 0.0199
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0334 0.0335
Toxoplasma gondii protease inhibitor PI2 0.002 0.0069 0.0396
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0015 0.0043 0.0043
Mycobacterium leprae Probable lipase LipE 0.0078 0.0391 0.2838
Trichomonas vaginalis ap endonuclease, putative 0.002 0.007 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0002
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.0002
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0043 0.0043
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0058 0.0058
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0082 0.0413 0.0413
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0134 0.0699 0.0699
Trypanosoma brucei heat shock protein, putative 0.0034 0.0147 0.0147
Echinococcus multilocularis lamin 0.0029 0.0118 0.0118
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.007 0.007
Schistosoma mansoni steroid hormone receptor ad4bp 0.0082 0.0413 0.0413
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0173 0.0173
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0009 0.001 0.001
Onchocerca volvulus Putative organic anion transporter 0.0029 0.012 0.0233
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0058 0.0058
Plasmodium falciparum heat shock protein 90, putative 0.0014 0.0036 0.0026
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0046 0.0046
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0009 0.0008 0.0008
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0322 0.174 0.1734
Loa Loa (eye worm) hypothetical protein 0.0082 0.0413 0.0413
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0009 0.0008 0.003
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0185 0.1291
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Echinococcus multilocularis cysteine protease 0.0018 0.0058 0.0058
Loa Loa (eye worm) cysteine protease 0.0018 0.0058 0.0058
Echinococcus granulosus beta LACTamase domain containing family member 0.0078 0.0391 0.0391
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0058 0.0049
Schistosoma mansoni fk506 binding protein 0.0256 0.1376 0.1376
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0025 0.0017
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0256 0.1376 0.1378
Loa Loa (eye worm) nuclear receptor NHR-67 0.0039 0.0173 0.0173
Treponema pallidum heat shock protein 90 0.0027 0.0108 0.0101
Mycobacterium tuberculosis Conserved protein 0.0078 0.0391 0.1438
Echinococcus granulosus expressed protein 0.0397 0.2153 0.2153
Loa Loa (eye worm) hypothetical protein 0.0078 0.0391 0.0391
Echinococcus granulosus cathepsin l1 0.0018 0.0058 0.0058
Echinococcus multilocularis splicing factor 3b subunit 3 0.0029 0.012 0.012
Onchocerca volvulus 0.0029 0.012 0.0233
Trichomonas vaginalis ap endonuclease, putative 0.002 0.007 0.0062
Brugia malayi sodium-independent organic anion transporter family protein 0.0029 0.012 0.012
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.007 0.0062
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0072 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0082 0.0413 0.0413
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0027 0.0108 0.0734
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0218 0.0219
Schistosoma mansoni ferritin light chain 0.0009 0.0008 0.0008
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0108 0.0101
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0749 0.0749
Schistosoma mansoni nuclear receptor nhr-48 0.0039 0.0173 0.0173
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0749 0.0749
Schistosoma mansoni ferritin 0.0009 0.0008 0.0008
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0015 0.0043 0.0043
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0072 0.0072
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0391 0.0383
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0185 0.0185
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0043 0.0199 0.0199
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0218 0.0219
Onchocerca volvulus 0.0029 0.012 0.0233
Loa Loa (eye worm) ctsf protein 0.0018 0.0058 0.0058
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0046 0.0046
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0046 0.0046
Echinococcus granulosus cathepsin L 0.0009 0.001 0.001
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0015 0.0043 0.0043
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0043 0.0199 0.0199
Plasmodium falciparum endoplasmin, putative 0.0021 0.0074 0.0064
Entamoeba histolytica hypothetical protein 0.002 0.0072 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0334 0.0335
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0078 0.0391 0.0391
Mycobacterium tuberculosis Conserved hypothetical protein 0.0015 0.0043 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0256 0.1376 0.1371
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0218 0.0218
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0072 0.0072
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0072 0.0072
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0334 0.0335
Leishmania major serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0322 0.174 0.1743
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0199
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.002 0.0069 0.0069
Schistosoma mansoni ap endonuclease 0.002 0.007 0.007
Giardia lamblia Heat shock protein HSP 90-alpha 0.0027 0.0108 0.0039
Loa Loa (eye worm) TAR-binding protein 0.007 0.0346 0.0346
Echinococcus granulosus intermediate filament protein 0.0029 0.0118 0.0118
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0346 0.0346
Brugia malayi sodium-independent organic anion transporter family protein 0.0029 0.012 0.012
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0029 0.012 0.012
Schistosoma mansoni axis inhibition protein axin 0.002 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0029 0.012 0.012
Plasmodium vivax vivapain-2 0.0018 0.0058 0.0048
Echinococcus multilocularis thyroid hormone receptor alpha 0.0216 0.1153 0.1153
Plasmodium falciparum heat shock protein 90, putative 0.0014 0.0036 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0114 0.0106
Trypanosoma brucei heat shock protein, putative 0.0034 0.0147 0.0147
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0072 0.0072
Plasmodium vivax heat shock protein, putative 0.0014 0.0036 0.0026
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0322 0.174 0.1734
Loa Loa (eye worm) hypothetical protein 0.0078 0.0391 0.0391
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.001 0.001
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0082 0.0413 0.0413
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0173 0.0173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0046 0.0038
Echinococcus multilocularis musashi 0.0029 0.0118 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0334 0.0335
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Brugia malayi steroid hormone receptor 0.0082 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0082 0.0413 0.0413
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0657 0.3595 0.36
Brugia malayi Cytochrome P450 family protein 0.0026 0.0101 0.0101
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.1815 1 1
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.1559 0.8583 0.8583
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0058 0.0048
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0027 0.0108 0.0788
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0014 0.0006
Loa Loa (eye worm) hypothetical protein 0.0082 0.0413 0.0413
Leishmania major cathepsin L-like protease 0.0018 0.0058 0.0058
Onchocerca volvulus 0.0018 0.0058 0.008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0082 0.0413 0.0413
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0099 0.0091
Mycobacterium tuberculosis Conserved protein 0.0078 0.0391 0.1438
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0147 0.0147
Brugia malayi photoreceptor-specific nuclear receptor 0.0082 0.0413 0.0413
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0199 0.0199
Echinococcus granulosus follistatin 0.002 0.0069 0.0069
Leishmania major serine/threonine protein phosphatase, putative 0.0322 0.174 0.1743
Schistosoma mansoni lamin 0.0029 0.0118 0.0118
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0082 0.0413 0.0413
Brugia malayi hypothetical protein 0.0029 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0033 0.0033
Echinococcus multilocularis dna polymerase kappa 0.0043 0.0196 0.0196
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0072 0.0072
Onchocerca volvulus 0.0095 0.0484 0.1127
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.012 0.0689
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0199
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0256 0.1376 0.1378
Brugia malayi tailless protein 0.0039 0.0173 0.0173
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.1813 0.9986 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0082 0.0413 0.0413
Trypanosoma brucei DNA polymerase eta, putative 0.0015 0.0043 0.0043
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Mycobacterium tuberculosis Conserved protein 0.0078 0.0391 0.1438
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0058 0.008
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0046 0.0046
Schistosoma mansoni nuclear receptor 0.0039 0.0173 0.0173
Trichomonas vaginalis heat shock protein, putative 0.0034 0.0147 0.0139
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0072 0.0072
Giardia lamblia Hypothetical protein 0.0256 0.1376 0.1317
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0196 0.0196
Echinococcus granulosus mixed lineage leukemia protein mll 0.0011 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.1557 0.8573 0.8584
Brugia malayi Inositol-1 0.0041 0.0185 0.0185
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0134 0.0699 0.0699
Echinococcus multilocularis microtubule associated protein 2 0.0733 0.4015 0.4015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0391 0.0391
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0082 0.0413 0.0413
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0152 0.0144
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0058 0.005
Loa Loa (eye worm) hypothetical protein 0.0078 0.0391 0.0391
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.002 0.0072 0.0072
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0072 0.0072
Plasmodium vivax endoplasmin, putative 0.0034 0.0147 0.0137
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0082 0.0413 0.0413
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0072 0.0072
Schistosoma mansoni axis inhibition protein axin 0.002 0.0072 0.0072
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0013 0.0033 0.0033
Plasmodium vivax SET domain protein, putative 0.0095 0.0484 0.0475
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0082 0.0413 0.0413
Echinococcus granulosus cpg binding protein 0.0032 0.0138 0.0138
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0014 0.0036 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0099 0.0091
Loa Loa (eye worm) hypothetical protein 0.0009 0.0008 0.0008
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.007 0.007
Echinococcus granulosus ferritin 0.0009 0.0008 0.0008
Echinococcus multilocularis geminin 0.0357 0.1932 0.1932
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Schistosoma mansoni regulator of G protein signaling 0.002 0.0072 0.0072
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.007 0.0062
Schistosoma mansoni tar DNA-binding protein 0.007 0.0346 0.0346
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.1813 0.9986 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0173 0.0173
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.007 0.006
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0185 0.1061
Onchocerca volvulus 0.0031 0.0128 0.0253
Schistosoma mansoni immunophilin 0.1815 1 1
Schistosoma mansoni regulator of G protein signaling 0.002 0.0072 0.0072
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0101 0.0101
Schistosoma mansoni fkbp-rapamycin associated protein 0.0009 0.0008 0.0008
Echinococcus granulosus endoplasmin 0.0027 0.0108 0.0108
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.1813 0.9986 1
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0072 0.0072
Trypanosoma cruzi heat shock protein, putative 0.0014 0.0036 0.0036
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0039 0.0173 0.0173
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0322 0.174 0.1734
Trypanosoma brucei heat shock protein, putative 0.0034 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0173
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0391 0.0383
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0072 0.0064
Echinococcus multilocularis expressed protein 0.002 0.0069 0.0069
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0072 0.0072
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0014 0.0036 0.0027
Trypanosoma cruzi DNA polymerase eta, putative 0.0015 0.0043 0.0043
Brugia malayi hypothetical protein 0.0029 0.012 0.012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0196 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0072 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0114 0.0106
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0043 0.0199 0.0199
Schistosoma mansoni hypothetical protein 0.0357 0.1932 0.1932
Schistosoma mansoni regulator of G protein signaling 0.002 0.0072 0.0072
Echinococcus granulosus expressed protein 0.0009 0.0008 0.0008
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0196 0.0196
Trypanosoma brucei hypothetical protein, conserved 0.0078 0.0391 0.0391
Schistosoma mansoni retinoic acid receptor RXR 0.0082 0.0413 0.0413
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0138 0.0139
Schistosoma mansoni cpg binding protein 0.0032 0.0138 0.0138
Giardia lamblia Heat shock protein HSP 90-alpha 0.0034 0.0147 0.0078
Schistosoma mansoni lamin 0.0029 0.0118 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0082 0.0413 0.0413
Onchocerca volvulus 0.0039 0.0173 0.0364
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0025
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.0002
Brugia malayi prostaglandin transporter 0.0029 0.012 0.012
Leishmania major cytochrome p450-like protein 0.0026 0.0101 0.0101
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0072 0.0072
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0082 0.0413 0.0413
Echinococcus granulosus heat shock protein 90 0.0027 0.0108 0.0108
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0072 0.0072
Mycobacterium ulcerans hypothetical protein 0.0078 0.0391 0.0391
Echinococcus multilocularis cysteine protease 0.0018 0.0058 0.0058
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0185 0.0177
Brugia malayi Pre-SET motif family protein 0.0095 0.0484 0.0484
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0015 0.0043 0.0043
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0036 0.0036
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0196 0.0196
Entamoeba histolytica cysteine proteinase, putative 0.0009 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0173
Schistosoma mansoni organic anion transporter 0.0029 0.012 0.012
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.0002
Echinococcus multilocularis dna polymerase eta 0.0015 0.0043 0.0043
Echinococcus granulosus heat shock protein 0.0034 0.0147 0.0147
Trichomonas vaginalis immunophilin, putative 0.1813 0.9986 1
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0322 0.174 0.1734
Onchocerca volvulus 0.0029 0.0118 0.0227
Brugia malayi Cytochrome P450 family protein 0.0026 0.0101 0.0101
Echinococcus multilocularis fk506 binding protein 0.1813 0.9986 0.9986
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.007 0.007
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0009 0.0008 0.0008
Loa Loa (eye worm) inositol-1 0.0041 0.0185 0.0185
Entamoeba histolytica CPSF A subunit region protein, putative 0.0029 0.012 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Leishmania major hypothetical protein, conserved 0.0078 0.0391 0.0391
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0058 0.0049
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0152 0.0873
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0055 0.0055
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0046 0.0046
Schistosoma mansoni endoplasmin 0.0034 0.0147 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0152 0.0144
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0749 0.0749
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0256 0.1376 0.7907
Onchocerca volvulus 0.0018 0.0058 0.008
Echinococcus multilocularis tar DNA binding protein 0.007 0.0346 0.0346
Onchocerca volvulus 0.0082 0.0413 0.0952
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.002 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0014 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0082 0.0413 0.0413
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.1813 0.9986 0.9986
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0101 0.0101
Entamoeba histolytica hypothetical protein 0.002 0.0072 0.0064
Entamoeba histolytica cysteine proteinase 1, putative 0.0009 0.001 0.0002
Loa Loa (eye worm) nuclear hormone receptor 0.0039 0.0173 0.0173
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0161 0.0593
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0173 0.0173
Brugia malayi Endoplasmin precursor 0.0034 0.0147 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0113 0.0105
Echinococcus granulosus lamin 0.0029 0.0118 0.0118
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0749 0.0749
Toxoplasma gondii heat shock protein HSP90 0.0034 0.0147 0.0843
Brugia malayi PXA domain containing protein 0.002 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0072 0.0064
Echinococcus multilocularis lamin dm0 0.0029 0.0118 0.0118
Brugia malayi secreted modular calcium-binding protein 1 0.002 0.0069 0.0069
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0009 0.001 0.001
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.002 0.0069 0.0069
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0322 0.174 0.174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0334 0.0335
Brugia malayi intermediate filament protein 0.0029 0.0118 0.0118
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0072 0.0072
Schistosoma mansoni heat shock protein 0.0034 0.0147 0.0147
Echinococcus granulosus dna polymerase eta 0.0015 0.0043 0.0043
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0334 0.0335
Brugia malayi polk-prov protein 0.0032 0.0138 0.0139
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0082 0.0413 0.0413
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0058 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0165 0.0158
Echinococcus multilocularis cathepsin L 0.0009 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0078 0.0391 0.0391
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0165 0.0158
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0072 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Brugia malayi Steroid receptor seven-up type 2 0.0082 0.0413 0.0413
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0152 0.0144
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0009 0.001 0.001
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0218 0.0211
Schistosoma mansoni thyroid hormone receptor 0.0216 0.1153 0.1153
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0185 0.0185
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0082 0.0413 0.0413
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0322 0.174 0.1743
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0165 0.0158
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.0002
Echinococcus granulosus axis inhibition protein axin 0.002 0.0072 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0152 0.0144
Mycobacterium ulcerans bacterioferritin BfrB 0.0009 0.0008 0.0008
Schistosoma mansoni RAR-like nuclear receptor 0.0082 0.0413 0.0413
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0082 0.0413 0.0413
Brugia malayi cathepsin L-like precursor 0.0012 0.0025 0.0025
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0082 0.0413 0.0413
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0118 0.0118
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.007 0.007
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0256 0.1376 0.1378
Schistosoma mansoni thyroid hormone receptor 0.0216 0.1153 0.1153
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.1813 0.9986 0.9997
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0334 0.0335
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0072 0.0064
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0014
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0003 0.0003
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0199 0.0199
Loa Loa (eye worm) RNA binding protein 0.007 0.0346 0.0346
Trichomonas vaginalis DNA polymerase eta, putative 0.0043 0.0196 0.0188
Echinococcus granulosus tar DNA binding protein 0.007 0.0346 0.0346
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.03 0.1617 0.1619
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0196 0.0196
Mycobacterium ulcerans beta-lactamase 0.0078 0.0391 0.0391
Loa Loa (eye worm) hypothetical protein 0.0256 0.1376 0.1378
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0256 0.1376 0.1377
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.1559 0.8583 0.8583
Chlamydia trachomatis UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 0.0871 0.4778 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0029 0.0021
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0025
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0058 0.0058
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.002 0.0069 0.0396
Loa Loa (eye worm) hypothetical protein 0.0078 0.0391 0.0391
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0484 0.0484
Schistosoma mansoni tar DNA-binding protein 0.007 0.0346 0.0346
Brugia malayi nuclear receptor NHR-67 0.0039 0.0173 0.0173
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0009 0.0008 0.0059
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0108 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0152 0.0144
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0218 0.0219
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0058 0.005
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0256 0.1376 0.1376
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0256 0.1376 0.1377
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0082 0.0413 0.0413
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.007 0.0257
Echinococcus multilocularis serine protein kinase ATM 0.0009 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0134 0.0699 0.0699
Onchocerca volvulus Protein ultraspiracle homolog 0.0082 0.0413 0.0952
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Echinococcus granulosus thyroid hormone receptor alpha 0.0039 0.0173 0.0173
Schistosoma mansoni DNA polymerase eta 0.0015 0.0043 0.0043
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0218 0.021
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0218 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0113 0.0105
Loa Loa (eye worm) hypothetical protein 0.0028 0.0115 0.0115
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0101 0.0101
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.1813 0.9986 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0082 0.0413 0.0413
Onchocerca volvulus 0.0039 0.0173 0.0364
Brugia malayi SPARC precursor 0.002 0.0069 0.0069
Brugia malayi hypothetical protein 0.0039 0.0173 0.0173
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Plasmodium vivax hypothetical protein, conserved 0.0078 0.0391 0.0382
Brugia malayi Cathepsin L-like precursor 0.0012 0.0025 0.0025
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0011 0.002 0.002
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0082 0.0413 0.0413
Schistosoma mansoni hypothetical protein 0.0357 0.1932 0.1932
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.002 0.0069 0.0069
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.0002
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0009 0.0008 0.0008
Brugia malayi Cathepsin L-like precursor 0.0018 0.0058 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0165 0.0158
Leishmania major cathepsin L-like protease 0.0068 0.0334 0.0335
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.03 0.1617 0.1619
Schistosoma mansoni heat shock protein 0.0034 0.0147 0.0147
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0138 0.0139
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0256 0.1376 0.1371
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.002 0.0069 0.0396
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0259 0.139 0.139
Loa Loa (eye worm) hypothetical protein 0.002 0.0072 0.0072
Brugia malayi TAR-binding protein 0.007 0.0346 0.0346
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0173 0.0173
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0256 0.1376 0.7907
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0069
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.003 0.003
Toxoplasma gondii Hsp90 domain-containing protein 0.0014 0.0036 0.0207
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0082 0.0413 0.0413
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0118 0.0118
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0256 0.1376 0.1378
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0082 0.0413 0.0413
Echinococcus multilocularis heat shock protein 90 0.0027 0.0108 0.0108
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0256 0.1376 0.1369
Schistosoma mansoni tar DNA-binding protein 0.007 0.0346 0.0346
Schistosoma mansoni coup transcription factor 0.0082 0.0413 0.0413
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.007 0.007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0046 0.0046
Echinococcus granulosus cathepsin l1 0.0012 0.0025 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0334 0.0335
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0039 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.002 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.002 0.0072 0.0072
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0161 0.117
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0082 0.0413 0.0413
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0072 0.0072
Toxoplasma gondii splicing factor 3b, subunit 3, putative 0.0029 0.012 0.0689
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0009 0.001 0.001
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.1813 0.9986 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0058 0.005
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0173
Echinococcus granulosus nuclear receptor nhr 48 0.0039 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0018 0.0058 0.0058
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0058 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0025 0.0017
Schistosoma mansoni inositol monophosphatase 0.0041 0.0185 0.0185
Trypanosoma brucei protein phosphatase 2B, putative 0.0322 0.174 0.1743
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0029 0.012 0.012
Leishmania major cathepsin L-like protease 0.0018 0.0058 0.0058
Schistosoma mansoni ferritin 0.0009 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0173
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0334 0.0335
Entamoeba histolytica cysteine proteinase 2 0.0009 0.001 0.0002
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0322 0.174 0.174
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0058 0.0058
Echinococcus granulosus ecdysone induced protein 78C 0.0082 0.0413 0.0413
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0009 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0133 0.0125
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0256 0.1376 0.1376
Schistosoma mansoni agrin 0.002 0.0069 0.0069
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.1813 0.9986 1
Leishmania major cathepsin L-like protease 0.0018 0.0058 0.0058
Brugia malayi Cathepsin L-like precursor 0.0018 0.0058 0.0058
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0062 0.0302 0.0302
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0114 0.0106
Entamoeba histolytica hypothetical protein 0.002 0.0072 0.0064
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0039 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0069
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0128 0.0128
Trichomonas vaginalis esterase, putative 0.0078 0.0391 0.0383
Toxoplasma gondii cathepsin CPL 0.0018 0.0058 0.0331
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0058 0.005
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0173
Echinococcus multilocularis cpg binding protein 0.0032 0.0138 0.0138
Entamoeba histolytica deoxycytidyl transferase, putative 0.0015 0.0043 0.0034
Echinococcus granulosus cathepsin L cysteine protease 0.0009 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0173
Echinococcus granulosus splicing factor 3b subunit 3 0.0029 0.012 0.012
Onchocerca volvulus 0.002 0.0069 0.0108
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0046 0.0046
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0072 0.0072
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0196 0.0196
Schistosoma mansoni organic anion transporter 0.0029 0.012 0.012
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0067 0.0067
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.03 0.1617 0.1619
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0196 0.0196
Brugia malayi hypothetical protein 0.002 0.0072 0.0072
Schistosoma mansoni inositol monophosphatase 0.0041 0.0185 0.0185
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.1813 0.9986 1
Trypanosoma cruzi cysteine proteinase, putative 0.0009 0.001 0.001
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0058 0.0058
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0029 0.012 0.012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0058 0.005
Plasmodium vivax vivapain-2 0.0018 0.0058 0.0048
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0322 0.174 0.174
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0185 0.0185
Echinococcus multilocularis dnaJ subfamily B 0.0435 0.2363 0.2363
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.002 0.002
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0147 0.0139
Loa Loa (eye worm) hypothetical protein 0.0082 0.0413 0.0413
Trichomonas vaginalis conserved hypothetical protein 0.0256 0.1376 0.1371
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.1815 1 1
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0173 0.0173
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.007 0.006
Brugia malayi nuclear receptor NHR-88 0.0039 0.0173 0.0173
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0039 0.0173 0.0173
Trypanosoma cruzi heat shock protein 85, putative 0.0027 0.0108 0.0109
Echinococcus granulosus Solute carrier organic anion transporter family 0.0029 0.012 0.012
Schistosoma mansoni cpg binding protein 0.0031 0.0128 0.0128
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0185 0.0177
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0152 0.0144
Trichomonas vaginalis set domain proteins, putative 0.0748 0.4097 0.4098
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0199
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0147 0.0147
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0196 0.0196
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0298 0.1713
Brugia malayi Cathepsin L-like precursor 0.0018 0.0058 0.0058
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0173 0.0364
Echinococcus granulosus dna polymerase kappa 0.0043 0.0196 0.0196
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.0002
Schistosoma mansoni terminal deoxycytidyl transferase 0.0015 0.0043 0.0043
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0256 0.1376 0.7907
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.007 0.007
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0029 0.012 0.012
Loa Loa (eye worm) fibroinase 0.0018 0.0058 0.0058
Echinococcus multilocularis heat shock protein 90 0.0034 0.0147 0.0147
Trypanosoma brucei heat shock protein, putative 0.0034 0.0147 0.0147
Giardia lamblia Grp94/Hsp90 0.0027 0.0108 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0218 0.0211
Onchocerca volvulus 0.0018 0.0058 0.008
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0082 0.0413 0.0413
Echinococcus granulosus microtubule associated protein 2 0.0733 0.4015 0.4015
Toxoplasma gondii heat shock protein 75, putative 0.0014 0.0036 0.0207
Plasmodium vivax splicing factor 3B subunit 3, putative 0.0029 0.012 0.011
Trichomonas vaginalis heat shock protein, putative 0.0014 0.0036 0.0028
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0078 0.0391 0.0391
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0009 0.0008 0.003
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0322 0.174 0.1734
Plasmodium falciparum splicing factor 3B subunit 3, putative 0.0029 0.012 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0058 0.005
Loa Loa (eye worm) hypothetical protein 0.002 0.0072 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0082 0.0413 0.0413
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.012 0.012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0152 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0185 0.0177
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0391 0.0383
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0072 0.0064
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0095 0.0484 0.0484
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0256 0.1376 0.5068
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0082 0.0413 0.0413
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Echinococcus multilocularis ferritin 0.0009 0.0008 0.0008
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0043 0.0196 0.0188
Echinococcus granulosus agrin 0.002 0.0069 0.0069
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.0002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0336 0.0336
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Onchocerca volvulus 0.0257 0.1379 0.3326
Loa Loa (eye worm) hypothetical protein 0.0032 0.0138 0.0139
Brugia malayi Serine/threonine protein phosphatase 2B catalytic subunit 2 0.0322 0.174 0.1742
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0196 0.0196
Trypanosoma cruzi serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0322 0.174 0.1743
Toxoplasma gondii ABC1 family protein 0.0078 0.0391 0.2244
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0101 0.0101
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0023 0.0133
Trypanosoma brucei unspecified product 0.001 0.0017 0.0017
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0082 0.0413 0.0413
Brugia malayi nuclear hormone receptor family member nhr-6 0.0039 0.0173 0.0173
Mycobacterium ulcerans heat shock protein 90 0.0027 0.0108 0.0109
Trichomonas vaginalis fk506-binding protein, putative 0.0256 0.1376 0.1371
Loa Loa (eye worm) histone methyltransferase 0.0013 0.0031 0.0031
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.007 0.007
Toxoplasma gondii heat shock protein 90, putative 0.0034 0.0147 0.0843
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0058 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0082 0.0413 0.0413
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0072 0.0064
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.1813 0.9986 1
Brugia malayi Papain family cysteine protease containing protein 0.0009 0.001 0.001
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0074 0.0066
Schistosoma mansoni microtubule-associated protein tau 0.0733 0.4015 0.4015
Schistosoma mansoni intermediate filament proteins 0.0029 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0173
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0025 0.0017
Echinococcus granulosus histone lysine methyltransferase setb 0.0095 0.0484 0.0484
Trichomonas vaginalis endoplasmin, putative 0.0021 0.0074 0.0066
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0166 0.0166
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.0002
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0072 0.0072
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0009 0.0008 0.0008
Entamoeba histolytica cysteine proteinase, putative 0.0009 0.001 0.0002
Brugia malayi hypothetical protein 0.0039 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0015 0.0043 0.0043
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0082 0.0413 0.0413
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.1813 0.9986 1
Leishmania major peptidylprolyl isomerase-like protein 0.1813 0.9986 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.012 0.012
Brugia malayi CXXC zinc finger family protein 0.0031 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0029 0.012 0.012
Trypanosoma cruzi MFS transporter, putative 0.0029 0.012 0.012
Brugia malayi beta-lactamase 0.0078 0.0391 0.0391
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.002 0.002
Echinococcus multilocularis follistatin 0.002 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0078 0.0391 0.0391
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0081 0.0297
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0046 0.0046
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0391 0.0391
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0039 0.0173 0.0173
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0072 0.0072
Mycobacterium ulcerans hypothetical protein 0.03 0.1617 0.1619
Schistosoma mansoni regulator of G protein signaling 0.002 0.0072 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0334 0.0335
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0072 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0072 0.0072
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0196 0.0196
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0072 0.0072
Onchocerca volvulus 0.0018 0.0058 0.008
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0218 0.0219
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0391 0.0383
Leishmania major DNA polymerase eta, putative 0.0015 0.0043 0.0043
Echinococcus granulosus FTZ F1 alpha 0.0082 0.0413 0.0413
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.03 0.1617 0.161
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0095 0.0484 0.0484
Schistosoma mansoni regulator of G protein signaling 0.002 0.0072 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0082 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0173
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Trypanosoma brucei heat shock protein, putative 0.0034 0.0147 0.0147
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0256 0.1376 0.1317
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0334 0.0335
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0101 0.0101
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0014 0.0036 0.0036
Echinococcus granulosus cysteine protease 0.0009 0.001 0.001
Trypanosoma brucei heat shock protein 84, putative 0.0014 0.0036 0.0036
Plasmodium falciparum heat shock protein 90 0.0034 0.0147 0.0137
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0322 0.174 0.1734
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0218 0.0219
Schistosoma mansoni tar DNA-binding protein 0.007 0.0346 0.0346
Trypanosoma cruzi cysteine proteinase, putative 0.0009 0.001 0.001
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0014 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0317 0.1715 0.1717
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0069
Onchocerca volvulus 0.0029 0.012 0.0233
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0185 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Mycobacterium tuberculosis Probable lipase LipE 0.0078 0.0391 0.1438
Loa Loa (eye worm) hypothetical protein 0.0029 0.012 0.012
Brugia malayi ecdysone receptor 0.0039 0.0173 0.0173
Schistosoma mansoni cpg binding protein 0.0032 0.0138 0.0138
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0218 0.021
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.0002
Echinococcus multilocularis nuclear receptor nhr 48 0.0039 0.0173 0.0173
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0256 0.1376 0.1369
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0101 0.0101
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0108 0.0101
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0218 0.0219
Brugia malayi hypothetical protein 0.0043 0.0199 0.0199
Trichomonas vaginalis fk506 binding protein, putative 0.0256 0.1376 0.1371
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0254 0.0254
Mycobacterium ulcerans esterase/lipase LipP 0.0078 0.0391 0.0391
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0101 0.0101
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0082 0.0413 0.0952
Schistosoma mansoni ferritin 0.0009 0.0008 0.0008
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0173
Brugia malayi conserved hypotetical protein 0.0039 0.0173 0.0173
Toxoplasma gondii protein phosphatase 2B catalytic subunit, calcineurin family phosphatse superfamily protein 0.0322 0.174 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0185 0.0177
Brugia malayi Pre-SET motif family protein 0.0657 0.3595 0.3599
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0058 0.0058
Onchocerca volvulus 0.0078 0.0391 0.0898
Trichomonas vaginalis fk506-binding protein, putative 0.0256 0.1376 0.1371
Loa Loa (eye worm) heat shock protein 75 0.0014 0.0036 0.0036
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.007 0.0451
Brugia malayi Cathepsin L-like precursor 0.0012 0.0025 0.0025
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.002 0.0069 0.0396
Echinococcus multilocularis 0.03 0.1617 0.1617
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0046 0.0046
Brugia malayi beta-lactamase family protein 0.0078 0.0391 0.0391
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0127 0.012
Plasmodium falciparum serine/threonine protein phosphatase 2B catalytic subunit A 0.0322 0.174 0.1734
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0082 0.0413 0.0413
Onchocerca volvulus Putative organic anion transporter 0.0029 0.012 0.0233
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0082 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0173
Onchocerca volvulus 0.0018 0.0058 0.008
Trypanosoma cruzi heat shock protein 90, putative 0.0027 0.0108 0.0109
Schistosoma mansoni heat shock protein 0.0014 0.0036 0.0036
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.0461 0.0461
Echinococcus granulosus lamin dm0 0.0029 0.0118 0.0118
Echinococcus multilocularis expressed protein 0.0009 0.0008 0.0008
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0196 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0099 0.0091
Echinococcus granulosus FK506 binding protein 2 0.03 0.1617 0.1617
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0046 0.0038
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Brugia malayi Nuclear hormone receptor-like 1 0.0082 0.0413 0.0413
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0058 0.0058
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0256 0.1376 0.1378
Echinococcus granulosus dnaJ subfamily B 0.0435 0.2363 0.2363
Onchocerca volvulus 0.0078 0.0391 0.0898
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0029 0.012 0.012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0082 0.0413 0.0413
Mycobacterium ulcerans bacterioferritin BfrA 0.0009 0.0008 0.0008
Entamoeba histolytica cysteine proteinase, putative 0.0009 0.001 0.0002
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0072 0.0072
Toxoplasma gondii exonuclease III APE 0.002 0.007 0.0401
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.0025 0.0025
Onchocerca volvulus 0.0018 0.0058 0.008
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.1813 0.9986 1
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0009 0.0008 0.0008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.007 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0196 0.0196
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0166 0.0166
Brugia malayi RNA binding protein 0.007 0.0346 0.0346
Schistosoma mansoni ferritin 0.0009 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0173
Trypanosoma brucei unspecified product 0.001 0.0017 0.0017
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0256 0.1376 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0082 0.0413 0.0413
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0055 0.0055
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0749 0.0749
Giardia lamblia DINP protein human, muc B family 0.0022 0.0081 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0099 0.0091
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.1813 0.9986 0.9986
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0256 0.1376 0.1317
Echinococcus granulosus heat shock protein 90 0.0034 0.0147 0.0147
Brugia malayi heat shock protein 90 0.0034 0.0147 0.0147
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0185 0.0185
Schistosoma mansoni tar DNA-binding protein 0.007 0.0346 0.0346
Brugia malayi nuclear receptor NHR-88 0.0082 0.0413 0.0413
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0095 0.0484 0.278
Echinococcus multilocularis expressed protein 0.0397 0.2153 0.2153
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0072 0.0072
Echinococcus multilocularis ecdysone induced protein 78C 0.0082 0.0413 0.0413
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.1813 0.9986 1
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0173 0.0173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0099 0.0091
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0058 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0099 0.0091
Loa Loa (eye worm) beta-lactamase 0.0078 0.0391 0.0391
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0058 0.0058
Entamoeba histolytica cysteine proteinase, putative 0.0009 0.001 0.0002
Giardia lamblia GTOR 0.0047 0.0218 0.015
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0391 0.0391
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0029 0.012 0.012
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0039 0.0173 0.0173
Brugia malayi ecdysteroid receptor 0.0082 0.0413 0.0413
Schistosoma mansoni immunophilin 0.1815 1 1
Trypanosoma brucei hypothetical protein, conserved 0.0256 0.1376 0.1378
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0196 0.0196
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0391 0.0383
Onchocerca volvulus 0.0029 0.012 0.0233
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0072 0.0072
Brugia malayi beta-lactamase family protein 0.0078 0.0391 0.0391
Leishmania major cathepsin L-like protease 0.0068 0.0334 0.0335
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0749 0.0749
Leishmania major cathepsin L-like protease 0.0068 0.0334 0.0335
Schistosoma mansoni follistatin 0.002 0.0069 0.0069
Schistosoma mansoni ap endonuclease 0.002 0.007 0.007
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0082 0.0413 0.0413
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0218 0.0219
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0196 0.0196
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0046 0.0046
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0036 0.0036
Mycobacterium leprae conserved hypothetical protein 0.0078 0.0391 0.2838
Schistosoma mansoni ferritin light chain 0.0009 0.0008 0.0008
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0081 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0081 0.0081
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0334 0.0335
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0058 0.0058
Brugia malayi orphan nuclear receptor NR2E1 0.0039 0.0173 0.0173
Trypanosoma cruzi heat shock protein 90, putative 0.0034 0.0147 0.0147
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1756 0.9674 0.9674
Leishmania major cathepsin L-like protease 0.0018 0.0058 0.0058
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0256 0.1376 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0099 0.0091
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0256 0.1376 0.1369
Schistosoma mansoni protein phosphatase-2b 0.0322 0.174 0.174
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0039 0.0173 0.0173
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0185 0.0185
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.002 0.0069 0.0069
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0143 0.0749 0.075
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.0002
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0166 0.0166
Brugia malayi sodium-independent organic anion transporter family protein 0.0029 0.012 0.012
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0256 0.1376 0.1317
Loa Loa (eye worm) hypothetical protein 0.0082 0.0413 0.0413
Leishmania major heat shock protein 83-1 0.0034 0.0147 0.0147
Schistosoma mansoni immunophilin 0.1559 0.8583 0.8583
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0072 0.0072
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0256 0.1376 0.1378
Brugia malayi hypothetical protein 0.002 0.0072 0.0072
Onchocerca volvulus 0.0029 0.0118 0.0227
Leishmania major fk506-binding protein 1-like protein 0.1813 0.9986 1
Schistosoma mansoni zinc finger protein 0.0039 0.0173 0.0173
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0078 0.0391 0.1438
Loa Loa (eye worm) endoplasmin 0.0034 0.0147 0.0147
Trypanosoma cruzi Heat shock protein 83, putative 0.0034 0.0147 0.0147
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0082 0.0413 0.0413
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0078 0.0391 0.1438
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0031 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0082 0.0413 0.0413
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0082 0.0413 0.0413
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.1815 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0196 0.0196
Trypanosoma brucei heat shock protein, putative 0.0034 0.0147 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0082 0.0413 0.0413
Trypanosoma brucei heat shock protein, putative 0.0034 0.0147 0.0147
Echinococcus granulosus serine protein kinase ATM 0.0009 0.0008 0.0008
Loa Loa (eye worm) heat shock protein 90 0.0034 0.0147 0.0147
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0058 0.005
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0256 0.1376 0.1378
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0173 0.0173
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0027 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0173
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0009 0.0008 0.0008
Onchocerca volvulus Putative organic anion transporter 0.0029 0.012 0.0233
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0334 0.0335
Schistosoma mansoni nuclear hormone receptor 0.0082 0.0413 0.0413
Trypanosoma cruzi cysteine peptidase, putative 0.0009 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0046 0.0038
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0058 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.001 0.001
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.03 0.1617 0.1619
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0322 0.174 0.1743
Onchocerca volvulus 0.0078 0.0391 0.0898
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.03 0.1617 0.1619
Onchocerca volvulus 0.0256 0.1376 0.3318
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0072 0.0072
Toxoplasma gondii FATC domain-containing protein 0.0009 0.0008 0.0047
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0046 0.0046
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0027 0.0108 0.0109
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0044 0.0044
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0173 0.0364
Onchocerca volvulus Bile acid receptor homolog 0.0082 0.0413 0.0952
Trichomonas vaginalis spliceosomal protein sap, putative 0.0029 0.012 0.0112
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.002 0.0069 0.0396
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0072 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0165 0.0158
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0082 0.0413 0.0413
Loa Loa (eye worm) RGS-3 protein 0.002 0.0072 0.0072
Brugia malayi nuclear hormone receptor 0.0039 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0012
Leishmania major DNA polymerase kappa, putative 0.0022 0.0081 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0058 0.005
Brugia malayi Cathepsin L-like precursor 0.0018 0.0058 0.0058
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0256 0.1376 0.1378
Echinococcus granulosus geminin 0.0357 0.1932 0.1932
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0082 0.0413 0.0413
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0058 0.005
Brugia malayi Cathepsin L-like precursor 0.0018 0.0058 0.0058
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0322 0.174 0.174
Loa Loa (eye worm) FKBP5 protein 0.1813 0.9986 1
Leishmania major cathepsin L-like protease 0.0018 0.0058 0.0058
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0082 0.0413 0.0413
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.1813 0.9986 1
Brugia malayi PXA domain containing protein 0.002 0.0072 0.0072
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.1813 0.999 1
Schistosoma mansoni apoferritin-2 0.0009 0.0008 0.0008
Trypanosoma brucei unspecified product 0.0036 0.0158 0.0158
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0072 0.0072
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0058 0.0058
Entamoeba histolytica cysteine protease, putative 0.0018 0.0058 0.0049
Schistosoma mansoni protein phosphatase-2b 0.0322 0.174 0.174
Loa Loa (eye worm) steroid hormone receptor 0.0082 0.0413 0.0413
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0072 0.0072
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0147 0.0139
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.1813 0.9986 1
Brugia malayi nuclear hormone receptor 0.0082 0.0413 0.0413
Trypanosoma brucei Heat shock protein 83, putative 0.0034 0.0147 0.0147

Activities

Activity type Activity value Assay description Source Reference
Kd (binding) = 2 uM Binding affinity to Aquifex aeolicus LpxC by isothermal titration calorimetry ChEMBL. 17296300

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.