Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.003 | 0.0052 | 0.0052 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1213 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0013 |
Echinococcus granulosus | FK506 binding protein 8 38 kDa | 0.019 | 0.1213 | 0.1213 |
Plasmodium falciparum | plasmepsin IV | 0.0505 | 0.3485 | 0.3547 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0505 | 0.3485 | 1 |
Brugia malayi | Eukaryotic aspartyl protease family protein | 0.0119 | 0.0701 | 0.0711 |
Onchocerca volvulus | 0.0194 | 0.1242 | 1 | |
Schistosoma mansoni | immunophilin | 0.1407 | 1 | 1 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.1217 | 0.8626 | 0.8626 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1213 | 0.1234 |
Leishmania major | FKBP-type peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Echinococcus granulosus | STIP1 y and U box containing protein 1 | 0.0024 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0141 | 0.0143 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type , putative | 0.1407 | 1 | 1 |
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase FKBP35 | 0.1383 | 0.9825 | 1 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 | 0.019 | 0.1213 | 0.1231 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-12 | 0.1383 | 0.9825 | 1 |
Giardia lamblia | 70 kDa peptidylprolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Plasmodium vivax | aspartyl protease, putative | 0.0119 | 0.0701 | 0.0713 |
Onchocerca volvulus | 0.0119 | 0.0701 | 0.5639 | |
Schistosoma mansoni | immunophilin FK506 binding protein FKBP12 | 0.1383 | 0.9825 | 0.9825 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.1383 | 0.9825 | 1 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.0051 | 0.0207 | 0.0207 |
Trypanosoma brucei | serine/threonine protein phosphatase 5 | 0.0024 | 0.0013 | 0.0013 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.019 | 0.1213 | 0.1234 |
Plasmodium vivax | plasmepsin V, putative | 0.0119 | 0.0701 | 0.0713 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0014 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Plasmodium falciparum | plasmepsin I | 0.0505 | 0.3485 | 0.3547 |
Loa Loa (eye worm) | UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase | 0.0024 | 0.0013 | 0.0014 |
Schistosoma mansoni | glutamate receptor kainate | 0.0025 | 0.0018 | 0.0018 |
Onchocerca volvulus | 0.019 | 0.1213 | 0.9763 | |
Trypanosoma cruzi | stress-inducible protein STI1-like, putative | 0.0024 | 0.0013 | 0.0014 |
Onchocerca volvulus | 0.0024 | 0.0013 | 0.0106 | |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.003 | 0.0052 | 0.0052 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Schistosoma mansoni | protein phosphatase-5 | 0.0024 | 0.0013 | 0.0013 |
Giardia lamblia | Hypothetical protein | 0.019 | 0.1213 | 0.1223 |
Treponema pallidum | peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) | 0.019 | 0.1213 | 0.1223 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0505 | 0.3485 | 0.3547 |
Loa Loa (eye worm) | TPR Domain containing protein | 0.0024 | 0.0013 | 0.0013 |
Chlamydia trachomatis | peptidyl-prolyl cis-trans isomerase | 0.019 | 0.1213 | 0.5 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0025 | 0.0018 | 0.0018 |
Plasmodium falciparum | plasmepsin X | 0.0119 | 0.0701 | 0.0713 |
Schistosoma mansoni | fk506 binding protein | 0.019 | 0.1213 | 0.1213 |
Mycobacterium ulcerans | FK-506 binding protein, peptidyl-prolyl cis-trans isomerase | 0.1383 | 0.9825 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0505 | 0.3485 | 0.3547 |
Echinococcus granulosus | stress induced phosphoprotein 1 | 0.0028 | 0.0043 | 0.0043 |
Trypanosoma brucei | small glutamine-rich tetratricopeptide repeat protein, putative | 0.0024 | 0.0013 | 0.0014 |
Entamoeba histolytica | TPR repeat protein | 0.0024 | 0.0013 | 0.0013 |
Trichomonas vaginalis | chaperone binding protein, putative | 0.0024 | 0.0013 | 0.0014 |
Entamoeba histolytica | hypothetical protein, conserved domain containing | 0.0024 | 0.0013 | 0.0013 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.1383 | 0.9825 | 1 |
Entamoeba histolytica | heat shock protein STI1, putative | 0.0024 | 0.0013 | 0.0013 |
Onchocerca volvulus | Kinesin light chain homolog | 0.0024 | 0.0013 | 0.0106 |
Schistosoma mansoni | glutamate receptor NMDA | 0.003 | 0.0052 | 0.0052 |
Entamoeba histolytica | TPR repeat protein | 0.0024 | 0.0013 | 0.0013 |
Plasmodium vivax | plasmepsin IV, putative | 0.0505 | 0.3485 | 0.3547 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.003 | 0.0052 | 0.0052 |
Echinococcus multilocularis | glutamate receptor 4 | 0.0042 | 0.0141 | 0.0141 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Trichomonas vaginalis | O-linked N-acetylglucosamine transferase, ogt, putative | 0.0028 | 0.0043 | 0.0043 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.019 | 0.1213 | 0.3481 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Plasmodium vivax | Hsp70/Hsp90 organizing protein, putative | 0.0024 | 0.0013 | 0.0014 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0013 |
Toxoplasma gondii | tetratricopeptide repeat domain containing protein | 0.0024 | 0.0013 | 0.0038 |
Loa Loa (eye worm) | FKBP5 protein | 0.1383 | 0.9825 | 1 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.1407 | 1 | 1 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 | 0.1387 | 0.9855 | 1 |
Leishmania major | peptidylprolyl isomerase-like protein | 0.1383 | 0.9825 | 1 |
Onchocerca volvulus | Tetratricopeptide repeat protein 5 homolog | 0.0024 | 0.0013 | 0.0106 |
Plasmodium vivax | aspartyl protease, putative | 0.0119 | 0.0701 | 0.0713 |
Plasmodium falciparum | plasmepsin VIII, putative | 0.0119 | 0.0701 | 0.0713 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0025 | 0.0018 | 0.0018 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 | 0.1383 | 0.9825 | 0.997 |
Brugia malayi | Pepsin A precursor | 0.0119 | 0.0701 | 0.0711 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0013 | 0.0013 |
Echinococcus granulosus | FK506 binding protein 2 | 0.019 | 0.1213 | 0.1213 |
Leishmania major | peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative | 0.019 | 0.1213 | 0.1234 |
Echinococcus multilocularis | 0.019 | 0.1213 | 0.1213 | |
Brugia malayi | TPR Domain containing protein | 0.0024 | 0.0013 | 0.0014 |
Echinococcus granulosus | glutamate receptor 4 | 0.0042 | 0.0141 | 0.0141 |
Trypanosoma cruzi | serine/threonine protein phosphatase type 5, putative | 0.0024 | 0.0013 | 0.0013 |
Trichomonas vaginalis | immunophilin, putative | 0.1383 | 0.9825 | 1 |
Loa Loa (eye worm) | TPR Domain containing protein | 0.0024 | 0.0013 | 0.0014 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.019 | 0.1213 | 0.1223 |
Plasmodium vivax | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.003 | 0.0052 | 0.0052 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.019 | 0.1213 | 0.3481 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0025 | 0.0018 | 0.0018 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.019 | 0.1213 | 0.5 |
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase, putative | 0.0024 | 0.0013 | 0.0013 |
Onchocerca volvulus | 0.0119 | 0.0701 | 0.5639 | |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.1383 | 0.9825 | 1 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0505 | 0.3485 | 1 |
Toxoplasma gondii | eukaryotic aspartyl protease superfamily protein | 0.0119 | 0.0701 | 0.201 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0013 |
Mycobacterium tuberculosis | Probable trigger factor (TF) protein Tig | 0.019 | 0.1213 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0701 | 0.0713 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0067 | 0.032 | 0.0326 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0141 | 0.0143 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase, putative | 0.1383 | 0.9825 | 1 |
Trypanosoma brucei | stress-induced protein sti1, putative | 0.0024 | 0.0013 | 0.0014 |
Echinococcus granulosus | glutamate receptor 1 | 0.0042 | 0.0141 | 0.0141 |
Plasmodium falciparum | Hsp70/Hsp90 organizing protein | 0.0024 | 0.0013 | 0.0014 |
Loa Loa (eye worm) | aspartic protease BmAsp-1 | 0.0119 | 0.0701 | 0.0713 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0024 | 0.0013 | 0.0013 |
Toxoplasma gondii | peptidyl-prolyl isomerase FKBP12, putative | 0.019 | 0.1213 | 0.3481 |
Trypanosoma brucei | stress-inducible protein STI1-like, putative | 0.0024 | 0.0013 | 0.0014 |
Echinococcus granulosus | glutamate receptor 2 | 0.0071 | 0.0354 | 0.0354 |
Onchocerca volvulus | 0.0028 | 0.0043 | 0.0345 | |
Echinococcus multilocularis | mitochondrial import receptor subunit tom34 | 0.0024 | 0.0013 | 0.0013 |
Plasmodium vivax | 70 kDa peptidylprolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma brucei | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type , putative | 0.019 | 0.1213 | 0.1213 |
Echinococcus multilocularis | STIP1 y and U box containing protein 1 | 0.0024 | 0.0013 | 0.0013 |
Echinococcus multilocularis | stress induced phosphoprotein 1 | 0.0028 | 0.0043 | 0.0043 |
Trypanosoma cruzi | serine/threonine protein phosphatase type 5, putative | 0.0024 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0505 | 0.3485 | 0.3547 |
Trichomonas vaginalis | chaperone binding protein, putative | 0.0024 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-30 | 0.019 | 0.1213 | 0.1234 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0701 | 0.0713 |
Plasmodium falciparum | plasmepsin IX | 0.0119 | 0.0701 | 0.0713 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Echinococcus multilocularis | Tetratricopeptide repeat protein 1 | 0.0024 | 0.0013 | 0.0013 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type, putative | 0.1407 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0014 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0025 | 0.0018 | 0.0018 |
Schistosoma mansoni | heat shock protein 70 | 0.0024 | 0.0013 | 0.0013 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0025 | 0.0018 | 0.0018 |
Echinococcus multilocularis | small glutamine rich tetratricopeptide | 0.0024 | 0.0013 | 0.0013 |
Brugia malayi | aspartic protease BmAsp-2, identical | 0.0119 | 0.0701 | 0.0711 |
Trichomonas vaginalis | conserved hypothetical protein | 0.019 | 0.1213 | 0.1234 |
Trypanosoma cruzi | FKBP-type peptidylprolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0013 | 0.0013 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Plasmodium falciparum | plasmepsin II | 0.0505 | 0.3485 | 0.3547 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0505 | 0.3485 | 0.3485 |
Trypanosoma brucei | FKBP-type peptidylprolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Echinococcus multilocularis | fk506 binding protein | 0.1383 | 0.9825 | 0.9825 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.019 | 0.1213 | 0.3481 |
Plasmodium falciparum | plasmepsin VII | 0.0119 | 0.0701 | 0.0713 |
Trichomonas vaginalis | fk506 binding protein, putative | 0.019 | 0.1213 | 0.1234 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0014 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0025 | 0.0018 | 0.0018 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0071 | 0.0354 | 0.0354 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-13 | 0.019 | 0.1213 | 0.1234 |
Toxoplasma gondii | aspartyl protease | 0.0119 | 0.0701 | 0.201 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.003 | 0.0052 | 0.0052 |
Brugia malayi | hypothetical protein | 0.0119 | 0.0701 | 0.0711 |
Toxoplasma gondii | O-linked N-acetylglucosamine transferase | 0.0024 | 0.0013 | 0.0038 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Schistosoma mansoni | heat shock protein 70 | 0.0024 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | TPR domain-containing protein | 0.0024 | 0.0013 | 0.0014 |
Echinococcus multilocularis | O glycosyltransferase | 0.0024 | 0.0013 | 0.0013 |
Treponema pallidum | peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) | 0.1383 | 0.9825 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.1383 | 0.9825 | 1 |
Onchocerca volvulus | 0.0024 | 0.0013 | 0.0106 | |
Toxoplasma gondii | aspartyl protease ASP3 | 0.0119 | 0.0701 | 0.201 |
Mycobacterium leprae | PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG | 0.019 | 0.1213 | 0.5 |
Echinococcus granulosus | mitochondrial import receptor subunit tom34 | 0.0024 | 0.0013 | 0.0013 |
Echinococcus multilocularis | FK506 binding protein 8, 38 kDa | 0.0215 | 0.1388 | 0.1388 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0786 | 0.5512 | 0.5512 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-33 | 0.019 | 0.1213 | 0.1234 |
Leishmania major | fk506-binding protein 1-like protein | 0.1383 | 0.9825 | 1 |
Echinococcus granulosus | glutamate receptor 2 | 0.0062 | 0.0288 | 0.0288 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0043 | 0.0043 |
Trichomonas vaginalis | chaperone binding protein, putative | 0.0024 | 0.0013 | 0.0014 |
Plasmodium vivax | aspartyl protease, putative | 0.0119 | 0.0701 | 0.0713 |
Loa Loa (eye worm) | hypothetical protein | 0.1197 | 0.8481 | 0.8631 |
Schistosoma mansoni | o-linked n-acetylglucosamine transferase ogt | 0.0024 | 0.0013 | 0.0013 |
Echinococcus granulosus | O glycosyltransferase | 0.0024 | 0.0013 | 0.0013 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0062 | 0.0288 | 0.0288 |
Trypanosoma cruzi | N-acetyltransferase subunit Nat1, putative | 0.0024 | 0.0013 | 0.0013 |
Schistosoma mansoni | immunophilin | 0.1217 | 0.8626 | 0.8626 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0067 | 0.032 | 0.0325 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0505 | 0.3485 | 0.3485 |
Schistosoma mansoni | DNAj homolog subfamily C member | 0.0028 | 0.0043 | 0.0043 |
Schistosoma mansoni | hypothetical protein | 0.019 | 0.1213 | 0.1213 |
Schistosoma mansoni | DNAj homolog subfamily C member | 0.0028 | 0.0043 | 0.0043 |
Trichomonas vaginalis | chaperone binding protein, putative | 0.0024 | 0.0013 | 0.0013 |
Plasmodium falciparum | plasmepsin III | 0.0119 | 0.0701 | 0.0713 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0119 | 0.0701 | 0.0713 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Leishmania major | stress-inducible protein STI1 homolog | 0.0028 | 0.0043 | 0.0043 |
Schistosoma mansoni | glutamate receptor kainate | 0.0025 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0141 | 0.0143 |
Brugia malayi | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase | 0.0024 | 0.0013 | 0.0014 |
Trypanosoma brucei | stress-inducible protein STI1-like, putative | 0.0024 | 0.0013 | 0.0014 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0505 | 0.3485 | 0.3547 |
Brugia malayi | TPR Domain containing protein | 0.0024 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | TPR Domain containing protein | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma brucei | stress-inducible protein STI1-like, putative | 0.0024 | 0.0013 | 0.0014 |
Trypanosoma cruzi | small glutamine-rich tetratricopeptide repeat protein, putative | 0.0024 | 0.0013 | 0.0014 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.019 | 0.1213 | 0.1234 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0067 | 0.032 | 0.0325 |
Plasmodium falciparum | plasmepsin VI | 0.0505 | 0.3485 | 0.3547 |
Trypanosoma cruzi | N-acetyltransferase subunit Nat1, putative | 0.0024 | 0.0013 | 0.0013 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 | 0.019 | 0.1213 | 0.1231 |
Trypanosoma brucei | hypothetical protein, conserved | 0.019 | 0.1213 | 0.1234 |
Plasmodium vivax | peptidyl-prolyl cis-trans isomerase, putative | 0.0024 | 0.0013 | 0.0013 |
Leishmania major | stress-induced protein sti1 | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0013 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.1217 | 0.8626 | 0.8626 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Leishmania major | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0071 | 0.0354 | 0.0354 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0071 | 0.0354 | 0.0354 |
Brugia malayi | aspartic protease BmAsp-1, identical | 0.0119 | 0.0701 | 0.0711 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0043 | 0.0044 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0786 | 0.5512 | 0.5512 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.0051 | 0.0207 | 0.0207 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Echinococcus granulosus | Tetratricopeptide repeat protein 1 | 0.0024 | 0.0013 | 0.0013 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0505 | 0.3485 | 0.3485 |
Schistosoma mansoni | immunophilin | 0.1407 | 1 | 1 |
Trypanosoma brucei | macrophage infectivity potentiator, precursor, putative | 0.019 | 0.1213 | 0.1234 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.019 | 0.1213 | 0.1223 |
Brugia malayi | TPR Domain containing protein | 0.0024 | 0.0013 | 0.0013 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0025 | 0.0018 | 0.0018 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.019 | 0.1213 | 0.1223 |
Trypanosoma brucei | TPR-repeat-containing chaperone protein DNAJ, putative | 0.0028 | 0.0043 | 0.0043 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP1A | 0.1383 | 0.9825 | 0.9825 |
Trichomonas vaginalis | conserved hypothetical protein | 0.019 | 0.1213 | 0.1234 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.019 | 0.1213 | 0.5 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 | 0.019 | 0.1213 | 0.1231 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Trypanosoma cruzi | stress-inducible protein STI1-like, putative | 0.0024 | 0.0013 | 0.0014 |
Trypanosoma cruzi | FKBP-type peptidylprolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Brugia malayi | hypothetical protein | 0.0119 | 0.0701 | 0.0711 |
Echinococcus granulosus | small glutamine rich tetratricopeptide | 0.0024 | 0.0013 | 0.0013 |
Plasmodium falciparum | plasmepsin V | 0.0119 | 0.0701 | 0.0713 |
Schistosoma mansoni | glutamate receptor kainate | 0.0025 | 0.0018 | 0.0018 |
Trypanosoma cruzi | macrophage infectivity potentiator, precursor, putative | 0.019 | 0.1213 | 0.1234 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.003 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | aspartyl protease 6 | 0.0119 | 0.0701 | 0.0713 |
Leishmania major | small glutamine-rich tetratricopeptide repeat protein, putative | 0.0024 | 0.0013 | 0.0014 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0067 | 0.032 | 0.032 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 14.5 % | Vasorelaxant activity against KCl-induced contraction in Wistar rat aorta at 10 ug/ml | ChEMBL. | 17547457 |
IC50 (functional) | = 5.8 uM | Vasorelaxant activity against KCl-induced contraction in Wistar rat aorta | ChEMBL. | 17547457 |
IC50 (ADMET) | = 118.3 uM | Cytotoxicity against human HeLa cells by MTT method | ChEMBL. | 17547457 |
IC50 (ADMET) | = 118.3 uM | Cytotoxicity against human HeLa cells by MTT method | ChEMBL. | 17547457 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.