Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0681 | 0.0681 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Loa Loa (eye worm) | LGC-31 protein | 0.0145 | 0.2115 | 0.2115 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0145 | 0.2115 | 0.2115 |
Brugia malayi | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0681 | 0.0681 |
Onchocerca volvulus | 0.0078 | 0.0681 | 0.0319 | |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0078 | 0.0681 | 0.1333 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0067 | 0.044 | 0.054 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.042 | 0.7996 | 1 |
Onchocerca volvulus | 0.0078 | 0.0681 | 0.0319 | |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0145 | 0.2115 | 0.2115 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0144 | 0.2098 | 0.2616 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0145 | 0.2115 | 0.2115 |
Brugia malayi | Neuronal acetylcholine receptor protein, alpha-2 chain precursor | 0.0067 | 0.044 | 0.044 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0149 | 0.2188 | 0.4321 |
Schistosoma mansoni | nAChR subunit | 0.0145 | 0.2115 | 0.4177 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0067 | 0.044 | 0.0855 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0681 | 0.0681 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Wolbachia endosymbiont of Brugia malayi | ribonucleotide-diphosphate reductase subunit alpha | 0.0117 | 0.1504 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Brugia malayi | Cation transporter family protein | 0.0282 | 0.5052 | 0.5052 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0145 | 0.2115 | 0.2115 |
Schistosoma mansoni | integrin alpha | 0.015 | 0.2211 | 0.4368 |
Loa Loa (eye worm) | acetyltransferase | 0.0149 | 0.2188 | 0.2188 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0145 | 0.2115 | 0.2115 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0145 | 0.2115 | 0.2115 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Echinococcus granulosus | receptor type guanylyl cyclase | 0.0193 | 0.3144 | 0.3925 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0145 | 0.2115 | 0.4177 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0067 | 0.044 | 0.044 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0145 | 0.2115 | 0.2638 |
Onchocerca volvulus | 0.0282 | 0.5052 | 0.6104 | |
Mycobacterium leprae | conserved hypothetical protein | 0.0347 | 0.6431 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0681 | 0.0681 |
Brugia malayi | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Schistosoma mansoni | tyrosine kinase | 0.0051 | 0.0091 | 0.0163 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0068 | 0.0468 | 0.0468 |
Treponema pallidum | ribonucleotide-diphosphate reductase subunit alpha | 0.0117 | 0.1504 | 0.5 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0145 | 0.2115 | 0.2115 |
Plasmodium vivax | ribonucleoside-diphosphate reductase large chain, putative | 0.0117 | 0.1504 | 0.5 |
Schistosoma mansoni | nAChR subunit | 0.0145 | 0.2115 | 0.4177 |
Trichomonas vaginalis | cyclin A, putative | 0.0083 | 0.0789 | 0.4411 |
Brugia malayi | ribonucleoside-diphosphate reductase large chain, putative | 0.0117 | 0.1504 | 0.1504 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0145 | 0.2115 | 0.2638 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0083 | 0.0789 | 0.0789 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0145 | 0.2115 | 0.2115 |
Chlamydia trachomatis | ribonucleoside-diphosphate reductase subunit alpha | 0.0117 | 0.1504 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.3617 | 0.3617 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Loa Loa (eye worm) | ribonucleoside-diphosphate reductase large subunit | 0.0117 | 0.1504 | 0.1504 |
Schistosoma mansoni | integrin alpha-ps | 0.0067 | 0.0443 | 0.0861 |
Echinococcus multilocularis | receptor type guanylyl cyclase | 0.0193 | 0.3144 | 0.3925 |
Brugia malayi | Guanylyl cyclase protein 23 | 0.0068 | 0.0468 | 0.0468 |
Schistosoma mansoni | nAChR subunit | 0.0145 | 0.2115 | 0.4177 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0067 | 0.044 | 0.044 |
Trichomonas vaginalis | cyclin B, putative | 0.0083 | 0.0789 | 0.4411 |
Echinococcus granulosus | integrin alpha 3 | 0.0115 | 0.1463 | 0.1821 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.5052 | 0.5052 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0078 | 0.0681 | 0.0681 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0193 | 0.3144 | 0.3144 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0067 | 0.044 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0681 | 0.0681 |
Trichomonas vaginalis | cyclins, putative | 0.0083 | 0.0789 | 0.4411 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0774 | 0.0774 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0789 | 0.0789 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.042 | 0.7996 | 0.7996 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0145 | 0.2115 | 0.2115 |
Mycobacterium ulcerans | adenylylate/guanylate cyclase | 0.0143 | 0.2058 | 0.1126 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0067 | 0.044 | 0.044 |
Entamoeba histolytica | cyclin, putative | 0.0083 | 0.0789 | 0.0188 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0145 | 0.2115 | 0.2638 |
Onchocerca volvulus | 0.0145 | 0.2115 | 0.2217 | |
Trichomonas vaginalis | cyclin B, putative | 0.0083 | 0.0789 | 0.4411 |
Trypanosoma cruzi | ribonucleoside-diphosphate reductase large chain, putative | 0.0117 | 0.1504 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0145 | 0.2115 | 0.4177 |
Onchocerca volvulus | 0.0145 | 0.2115 | 0.2217 | |
Plasmodium falciparum | ribonucleoside-diphosphate reductase large subunit, putative | 0.0117 | 0.1504 | 0.5 |
Schistosoma mansoni | protein kinase | 0.0193 | 0.3144 | 0.6217 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0047 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0047 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0145 | 0.2115 | 0.2115 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0145 | 0.2115 | 0.2115 |
Schistosoma mansoni | acetylcholine receptor-related | 0.0067 | 0.044 | 0.0855 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0149 | 0.2188 | 0.2188 |
Trypanosoma brucei | ribonucleoside-diphosphate reductase large chain | 0.0117 | 0.1504 | 1 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0145 | 0.2115 | 0.2638 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | ACC-1 protein | 0.0145 | 0.2115 | 0.2115 |
Brugia malayi | Integrin beta pat-3 precursor | 0.0306 | 0.555 | 0.555 |
Trichomonas vaginalis | cyclin B, putative | 0.0083 | 0.0789 | 0.4411 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Mycobacterium tuberculosis | Conserved protein | 0.0347 | 0.6431 | 1 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0078 | 0.0681 | 0.1333 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0078 | 0.0681 | 0.0681 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.1522 | 0.1522 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0145 | 0.2115 | 0.2638 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0513 | 1 | 1 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0149 | 0.2188 | 0.2728 |
Echinococcus multilocularis | tyrosine kinase | 0.0051 | 0.0091 | 0.0103 |
Echinococcus multilocularis | ribonucleoside diphosphate reductase large | 0.0117 | 0.1504 | 0.1872 |
Echinococcus multilocularis | integrin alpha 3 | 0.0115 | 0.1463 | 0.1821 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0193 | 0.3144 | 0.3144 |
Toxoplasma gondii | ribonucleoside-diphosphate reductase large chain | 0.0117 | 0.1504 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0145 | 0.2115 | 0.2115 |
Echinococcus multilocularis | cyclin B | 0.0083 | 0.0789 | 0.0977 |
Brugia malayi | Cation transporter family protein | 0.0145 | 0.2115 | 0.2115 |
Echinococcus granulosus | nAChR subunit | 0.0078 | 0.0681 | 0.0842 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0145 | 0.2115 | 0.2115 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0091 | 0.0091 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0145 | 0.2115 | 0.2638 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0145 | 0.2115 | 0.2115 |
Brugia malayi | Cation transporter family protein | 0.0145 | 0.2115 | 0.2115 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0145 | 0.2115 | 0.2638 |
Echinococcus multilocularis | nAChR subunit | 0.0145 | 0.2115 | 0.2638 |
Onchocerca volvulus | Putative nachr subunit | 0.042 | 0.7996 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0145 | 0.2115 | 0.2638 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0145 | 0.2115 | 0.2638 |
Echinococcus multilocularis | atrial natriuretic peptide receptor | 0.0168 | 0.2607 | 0.3253 |
Onchocerca volvulus | Atrial natriuretic peptide receptor 3 homolog | 0.0193 | 0.3144 | 0.3579 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0145 | 0.2115 | 0.2115 |
Echinococcus granulosus | nAChR subunit | 0.0145 | 0.2115 | 0.2638 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0789 | 0.0789 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0145 | 0.2115 | 0.2638 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0145 | 0.2115 | 0.2638 |
Schistosoma mansoni | tyrosine kinase | 0.0051 | 0.0091 | 0.0163 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0347 | 0.6431 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.143 | 0.143 |
Mycobacterium ulcerans | hypothetical protein | 0.0347 | 0.6431 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0145 | 0.2115 | 0.4177 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0145 | 0.2115 | 0.2638 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0347 | 0.6431 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.042 | 0.7996 | 0.7996 |
Loa Loa (eye worm) | integrin alpha pat-2 | 0.0231 | 0.3947 | 0.3947 |
Schistosoma mansoni | nAChR subunit | 0.0145 | 0.2115 | 0.4177 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.042 | 0.7996 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.1173 | 0.1173 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0145 | 0.2115 | 0.2115 |
Echinococcus granulosus | tyrosine kinase | 0.0051 | 0.0091 | 0.0103 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0145 | 0.2115 | 0.4177 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0193 | 0.3144 | 0.3144 |
Echinococcus multilocularis | integrin beta 2 | 0.0226 | 0.3854 | 0.4814 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0145 | 0.2115 | 0.2638 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0145 | 0.2115 | 0.2638 |
Loa Loa (eye worm) | integrin beta-2 | 0.0306 | 0.555 | 0.555 |
Echinococcus multilocularis | nAChR subunit | 0.0078 | 0.0681 | 0.0842 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0145 | 0.2115 | 0.2638 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0148 | 0.2176 | 0.2176 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0078 | 0.0681 | 0.0681 |
Onchocerca volvulus | 0.0083 | 0.0789 | 0.0462 | |
Loa Loa (eye worm) | ACC-1 protein | 0.0145 | 0.2115 | 0.2115 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0067 | 0.044 | 0.044 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0067 | 0.044 | 0.0855 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0681 | 0.0681 |
Echinococcus granulosus | integrin alpha ps | 0.0067 | 0.0443 | 0.0544 |
Echinococcus granulosus | atrial natriuretic peptide receptor | 0.0168 | 0.2607 | 0.3253 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0282 | 0.5052 | 1 |
Schistosoma mansoni | ribonucleoside-diphosphate reductase alpha subunit | 0.0117 | 0.1504 | 0.2965 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0145 | 0.2115 | 0.2638 |
Echinococcus granulosus | cyclin B | 0.0083 | 0.0789 | 0.0977 |
Brugia malayi | Integrin alpha cytoplasmic region family protein | 0.0113 | 0.143 | 0.143 |
Trichomonas vaginalis | cyclins, putative | 0.0083 | 0.0789 | 0.4411 |
Brugia malayi | Integrin alpha pat-2 precursor | 0.015 | 0.2211 | 0.2211 |
Trichomonas vaginalis | cyclins, putative | 0.0083 | 0.0789 | 0.4411 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0067 | 0.044 | 0.044 |
Brugia malayi | Acetylcholine receptor protein, alpha-like chain 1 precursor | 0.0067 | 0.044 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0009 | 0.0009 |
Mycobacterium ulcerans | hypothetical protein | 0.0347 | 0.6431 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Schistosoma mansoni | nAChR subunit | 0.0067 | 0.044 | 0.0855 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0078 | 0.0681 | 0.0681 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0083 | 0.0789 | 0.5 |
Brugia malayi | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.2176 | 0.2176 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0145 | 0.2115 | 0.2638 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Schistosoma mansoni | nAChR subunit | 0.0067 | 0.044 | 0.0855 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0145 | 0.2115 | 0.2115 |
Onchocerca volvulus | 0.0282 | 0.5052 | 0.6104 | |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0145 | 0.2115 | 0.2115 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0078 | 0.0681 | 0.0681 |
Echinococcus granulosus | ribonucleoside diphosphate reductase large | 0.0117 | 0.1504 | 0.1872 |
Schistosoma mansoni | nAChR subunit | 0.0145 | 0.2115 | 0.4177 |
Brugia malayi | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.042 | 0.7996 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.042 | 0.7996 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.042 | 0.7996 | 1 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.042 | 0.7996 | 0.7996 |
Loa Loa (eye worm) | neuronal acetylcholine receptor protein | 0.0067 | 0.044 | 0.044 |
Onchocerca volvulus | 0.0068 | 0.0468 | 0.0037 | |
Brugia malayi | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0145 | 0.2115 | 0.2115 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0145 | 0.2115 | 0.2115 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0681 | 0.0681 |
Trichomonas vaginalis | cyclin B, putative | 0.0083 | 0.0789 | 0.4411 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0145 | 0.2115 | 0.2115 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.0067 | 0.044 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.042 | 0.7996 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0101 | 0.1173 | 0.1173 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0681 | 0.0681 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0282 | 0.5052 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.1173 | 0.2308 |
Leishmania major | ribonucleoside-diphosphate reductase large chain, putative | 0.0117 | 0.1504 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0145 | 0.2115 | 0.4177 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0047 | 0.0009 | 0.0009 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0145 | 0.2115 | 0.2638 |
Onchocerca volvulus | 0.0282 | 0.5052 | 0.6104 | |
Schistosoma mansoni | integrin beta subunit | 0.018 | 0.286 | 0.5653 |
Schistosoma mansoni | nAChR subunit | 0.0145 | 0.2115 | 0.4177 |
Echinococcus multilocularis | integrin alpha ps | 0.0067 | 0.0443 | 0.0544 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0083 | 0.0789 | 0.0789 |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.0067 | 0.044 | 0.054 |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.0067 | 0.044 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.2115 | 0.2115 |
Echinococcus granulosus | integrin beta 2 | 0.0226 | 0.3854 | 0.4814 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.044 | 0.044 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0067 | 0.044 | 0.0855 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.5052 | 0.5052 |
Trichomonas vaginalis | cyclins, putative | 0.0083 | 0.0789 | 0.4411 |
Trichomonas vaginalis | ribonucleoside-diphosphate reductase alpha chain, putative | 0.0117 | 0.1504 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0078 | 0.0681 | 0.1333 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0145 | 0.2115 | 0.2638 |
Echinococcus multilocularis | integrin alpha ps | 0.0067 | 0.0443 | 0.0544 |
Onchocerca volvulus | 0.0145 | 0.2115 | 0.2217 | |
Loa Loa (eye worm) | acetylcholine receptor protein | 0.0067 | 0.044 | 0.044 |
Schistosoma mansoni | cyclin B | 0.0083 | 0.0789 | 0.1548 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (ADMET) | = 77.1 uM | Cytotoxicity against Vero cells | ChEMBL. | 17562368 |
MIC (functional) | = 6.39 uM | Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis CIBIN 687 isolates | ChEMBL. | 17562368 |
MIC (functional) | = 6.39 uM | Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis CIBIN 687 isolates | ChEMBL. | 17562368 |
MIC (functional) | = 12.77 uM | Antimycobacterial activity against streptomycin, isoniazid, ethambutol-resistant Mycobacterium tuberculosis CIBIN 112 isolates | ChEMBL. | 17562368 |
MIC (functional) | = 12.77 uM | Antimycobacterial activity against streptomycin, isoniazid, ethambutol-resistant Mycobacterium tuberculosis CIBIN 112 isolates | ChEMBL. | 17562368 |
MIC (functional) | = 25.54 uM | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv | ChEMBL. | 17562368 |
MIC (functional) | = 25.54 uM | Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis CIBIN 650 isolates | ChEMBL. | 17562368 |
MIC (functional) | = 25.54 uM | Antimycobacterial activity against streptomycin and isoniazid-resistant Mycobacterium tuberculosis CIBIN 675 isolates | ChEMBL. | 17562368 |
MIC (functional) | = 25.54 uM | Antimycobacterial activity against streptomycin, isoniazid, rifampicin, pyrazinamide-resistant Mycobacterium tuberculosis CIBIN 234 isolates | ChEMBL. | 17562368 |
MIC (functional) | = 25.54 uM | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv | ChEMBL. | 17562368 |
MIC (functional) | = 25.54 uM | Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis CIBIN 650 isolates | ChEMBL. | 17562368 |
MIC (functional) | = 25.54 uM | Antimycobacterial activity against streptomycin and isoniazid-resistant Mycobacterium tuberculosis CIBIN 675 isolates | ChEMBL. | 17562368 |
MIC (functional) | = 25.54 uM | Antimycobacterial activity against streptomycin, isoniazid, rifampicin, pyrazinamide-resistant Mycobacterium tuberculosis CIBIN 234 isolates | ChEMBL. | 17562368 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.