Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0031 | 0.0087 | 0.0188 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0018 | 0.0018 | 0.0028 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0126 | 0.0604 | 0.0455 |
Trichomonas vaginalis | heat shock protein, putative | 0.0039 | 0.0135 | 0.0069 |
Onchocerca volvulus | 0.0126 | 0.0604 | 0.1279 | |
Echinococcus granulosus | carbonyl reductase 1 | 0.0021 | 0.0033 | 0.0071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0018 | 0.0038 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0028 | 0.0075 | 0.0187 |
Mycobacterium ulcerans | acyl carrier protein | 0.0052 | 0.0204 | 0.005 |
Brugia malayi | hypothetical protein | 0.0066 | 0.028 | 0.0694 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0018 | 0.0044 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0018 | 0.0018 | 0.0028 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0018 | 0.0044 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.1854 | 1 | 1 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.1854 | 1 | 1 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0126 | 0.0604 | 0.0455 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0018 | 0.0022 | 0.0054 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0104 | 0.0487 | 0.0424 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.0171 | 0.1499 |
Schistosoma mansoni | carbonyl reductase | 0.0028 | 0.0075 | 0.012 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.0126 | 0.0604 | 0.9263 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0018 | 0.0044 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0028 | 0.0075 | 0.0162 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0018 | 0.0038 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.0171 | 0.1499 |
Brugia malayi | ecdysteroid receptor | 0.0018 | 0.0018 | 0.0044 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0046 | 0.0171 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0018 | 0.0038 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Brugia malayi | Endoplasmin precursor | 0.0046 | 0.0171 | 0.0423 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0018 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0018 | 0.0038 |
Echinococcus multilocularis | Acyl carrier protein, mitochondrial | 0.0052 | 0.0204 | 0.0441 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Onchocerca volvulus | 0.0027 | 0.0068 | 0.0112 | |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0104 | 0.0487 | 0.0424 |
Leishmania major | protein kinase, putative | 0.0104 | 0.0487 | 0.7222 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0018 | 0.0038 |
Schistosoma mansoni | endoplasmin | 0.0046 | 0.0171 | 0.0273 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0031 | 0.0087 | 0.0188 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.0327 | 0.4645 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0028 | 0.0075 | 0.0162 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0084 | 0.0379 | 0.0818 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.012 | 0.0572 | 0.124 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0126 | 0.0604 | 0.0455 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0018 | 0.0038 |
Schistosoma mansoni | carbonyl reductase | 0.0028 | 0.0075 | 0.012 |
Onchocerca volvulus | 0.03 | 0.1552 | 0.3345 | |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0126 | 0.0604 | 0.0455 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0174 | 0.0867 | 0.0806 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.0327 | 0.4645 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0104 | 0.0487 | 0.0424 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0104 | 0.0487 | 0.0424 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0046 | 0.0171 | 0.1499 |
Echinococcus granulosus | PP-binding domain containing protein | 0.0038 | 0.0129 | 0.0278 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.0327 | 0.4645 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0018 | 0.0018 | 0.0028 |
Onchocerca volvulus | 0.0066 | 0.028 | 0.0574 | |
Schistosoma mansoni | dihydropteridine reductase | 0.0126 | 0.0604 | 0.0968 |
Echinococcus granulosus | lamin | 0.0027 | 0.0068 | 0.0147 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0133 | 0.0646 | 0.0498 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0068 | 0.0169 |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0126 | 0.0604 | 0.0455 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0028 | 0.0075 | 0.0162 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0018 | 0.0044 |
Onchocerca volvulus | 0.0028 | 0.0075 | 0.0127 | |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Leishmania major | acyl carrier protein, putative | 0.0052 | 0.0204 | 0.2261 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0018 | 0.0044 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0126 | 0.0604 | 0.0455 |
Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0028 | 0.0075 | 0.08 |
Brugia malayi | heat shock protein 90 | 0.0046 | 0.0171 | 0.0423 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0293 | 0.0469 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0046 | 0.0171 | 0.0096 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0104 | 0.0487 | 0.7444 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0126 | 0.0604 | 0.0455 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0075 | 0.0327 | 0.0707 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0202 | 0.1018 | 0.2519 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0074 | 0.0322 | 0.0696 |
Echinococcus granulosus | endoplasmin | 0.0043 | 0.0156 | 0.0336 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0018 | 0.0044 |
Plasmodium falciparum | acyl carrier protein | 0.0052 | 0.0204 | 0.0139 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0126 | 0.0604 | 0.1494 |
Echinococcus multilocularis | heat shock protein 90 | 0.0046 | 0.0171 | 0.0369 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0126 | 0.0604 | 0.0455 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0126 | 0.0604 | 0.0455 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0691 | 0.368 | 0.5898 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0046 | 0.0171 | 0.1621 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0062 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0126 | 0.0604 | 0.0455 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0018 | 0.0044 |
Trypanosoma cruzi | heat shock protein, putative | 0.0031 | 0.0087 | 0.0989 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0126 | 0.0604 | 0.0455 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0018 | 0.0018 | 0.0038 |
Echinococcus multilocularis | roundabout 2 | 0.002 | 0.0029 | 0.0061 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0018 | 0.0018 | 0.0028 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0126 | 0.0604 | 0.0455 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0111 | 0.0523 | 0.0326 |
Plasmodium vivax | heat shock protein, putative | 0.0174 | 0.0867 | 0.0787 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0018 | 0.0038 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0018 | 0.0044 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0108 | 0.0506 | 0.1094 |
Toxoplasma gondii | acyl carrier protein ACP | 0.0052 | 0.0204 | 0.013 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Schistosoma mansoni | endoplasmin | 0.0046 | 0.0171 | 0.0273 |
Brugia malayi | acyl carrier protein, mitochondrial precursor, putative | 0.0052 | 0.0204 | 0.0506 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0068 | 0.0148 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0046 | 0.0171 | 0.1499 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0039 | 0.0135 | 0.1758 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0108 | 0.0506 | 0.1099 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0018 | 0.0038 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0046 | 0.0171 | 0.2339 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0126 | 0.0604 | 0.0455 |
Echinococcus granulosus | heat shock protein 90 | 0.0046 | 0.0171 | 0.0369 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0084 | 0.0379 | 0.0818 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0126 | 0.0604 | 0.0455 |
Echinococcus multilocularis | heat shock protein 90 | 0.0039 | 0.0135 | 0.0291 |
Leishmania major | pteridine reductase 1 | 0.0133 | 0.0646 | 1 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0104 | 0.0487 | 0.0424 |
Schistosoma mansoni | hypothetical protein | 0.0075 | 0.0327 | 0.0524 |
Echinococcus multilocularis | geminin | 0.017 | 0.0844 | 0.1824 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.0171 | 0.1499 |
Loa Loa (eye worm) | oxidoreductase | 0.0126 | 0.0604 | 0.1311 |
Brugia malayi | hypothetical protein | 0.0104 | 0.0487 | 0.1206 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.1854 | 1 | 1 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0126 | 0.0604 | 0.1311 |
Plasmodium falciparum | heat shock protein 90 | 0.0046 | 0.0171 | 0.0105 |
Mycobacterium leprae | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI | 0.0126 | 0.0604 | 0.0481 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0062 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0133 | 0.0646 | 0.0498 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0126 | 0.0604 | 0.0455 |
Schistosoma mansoni | carbonyl reductase | 0.0028 | 0.0075 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0066 | 0.0142 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0018 | 0.0018 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0487 | 0.1058 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0297 | 0.1534 | 0.3314 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.0171 | 0.1499 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0018 | 0.0018 | 0.0038 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0126 | 0.0604 | 0.9322 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.0126 | 0.0604 | 0.0455 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0126 | 0.0604 | 0.0455 |
Echinococcus granulosus | heat shock protein | 0.0046 | 0.0171 | 0.0369 |
Trichomonas vaginalis | heat shock protein, putative | 0.0043 | 0.0156 | 0.009 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0068 | 0.0148 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Echinococcus multilocularis | heat shock protein | 0.0046 | 0.0171 | 0.0369 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0018 | 0.0044 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0018 | 0.0028 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0018 | 0.0018 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0018 | 0.0038 |
Schistosoma mansoni | cell adhesion molecule | 0.0017 | 0.0011 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0366 | 0.0795 |
Onchocerca volvulus | 0.0018 | 0.0018 | 0.0002 | |
Echinococcus granulosus | single minded 2 | 0.0297 | 0.1534 | 0.3314 |
Plasmodium vivax | endoplasmin, putative | 0.0046 | 0.0171 | 0.0085 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0018 | 0.0018 | 0.0044 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0018 | 0.0018 | 0.0028 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.0171 | 0.1499 |
Echinococcus multilocularis | jun protein | 0.0084 | 0.0379 | 0.0818 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0043 | 0.0156 | 0.0027 |
Echinococcus granulosus | geminin | 0.017 | 0.0844 | 0.1824 |
Trypanosoma brucei | Acyl carrier protein, mitochondrial | 0.0052 | 0.0204 | 0.2099 |
Brugia malayi | Hsp90 protein | 0.0031 | 0.0087 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0011 | 0.0025 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0126 | 0.0604 | 0.0455 |
Schistosoma mansoni | heat shock protein | 0.0046 | 0.0171 | 0.0273 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0126 | 0.0604 | 0.1305 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0104 | 0.0487 | 0.7444 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0104 | 0.0487 | 0.0424 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0104 | 0.0487 | 0.7444 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0126 | 0.0604 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0 | 0.0001 |
Brugia malayi | aryl hydrocarbon receptor AHR-1 | 0.0758 | 0.4041 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Brugia malayi | nuclear receptor NHR-88 | 0.0018 | 0.0018 | 0.0044 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0039 | 0.0135 | 0.1758 |
Schistosoma mansoni | heat shock protein | 0.0046 | 0.0171 | 0.0273 |
Schistosoma mansoni | lamin | 0.0027 | 0.0068 | 0.0109 |
Giardia lamblia | Grp94/Hsp90 | 0.0043 | 0.0156 | 0.5748 |
Brugia malayi | bHLH-PAS transcription factor | 0.0297 | 0.1534 | 0.3795 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0126 | 0.0604 | 0.0455 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0017 | 0.0011 | 0.0024 |
Chlamydia trachomatis | oxoacy-ACP reductase | 0.0126 | 0.0604 | 0.0408 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0126 | 0.0604 | 0.0455 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0018 | 0.0038 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0866 | 0.4626 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.0327 | 0.4645 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0028 | 0.0075 | 0.0162 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0018 | 0.0018 | 0.0002 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0046 | 0.0171 | 0.0371 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0126 | 0.0604 | 0.0455 |
Schistosoma mansoni | heat shock protein | 0.0031 | 0.0087 | 0.0139 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0126 | 0.0604 | 0.0455 |
Echinococcus granulosus | neuroglian | 0.0016 | 0.0007 | 0.0013 |
Schistosoma mansoni | nephrin | 0.0016 | 0.0007 | 0.001 |
Trypanosoma brucei | pteridine reductase 1 | 0.0126 | 0.0604 | 0.9247 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0126 | 0.0604 | 0.0455 |
Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0028 | 0.0075 | 0.08 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.0171 | 0.1499 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Brugia malayi | steroid hormone receptor | 0.0018 | 0.0018 | 0.0044 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.1854 | 1 | 1 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0031 | 0.0087 | 0.0012 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0018 | 0.0022 | 0.0046 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.1162 | 0.6239 | 1 |
Schistosoma mansoni | single-minded | 0.0401 | 0.21 | 0.3365 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0046 | 0.0171 | 0.1621 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0018 | 0.0018 | 0.0038 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0104 | 0.0487 | 0.7444 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.0126 | 0.0604 | 0.0521 |
Trichomonas vaginalis | heat shock protein, putative | 0.0043 | 0.0156 | 0.009 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.012 | 0.0572 | 0.124 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0031 | 0.0087 | 0.0153 |
Mycobacterium ulcerans | 20-beta-hydroxysteroid dehydrogenase FabG3 | 0.0126 | 0.0604 | 0.0455 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0075 | 0.0327 | 0.0707 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0126 | 0.0604 | 0.0455 |
Onchocerca volvulus | 0.0185 | 0.0928 | 0.1984 | |
Echinococcus granulosus | acyl carrier protein mitochondrial | 0.0052 | 0.0204 | 0.0441 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0104 | 0.0487 | 0.7444 |
Mycobacterium ulcerans | putative regulatory protein | 0.0297 | 0.1534 | 0.14 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0046 | 0.0171 | 0.2339 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0126 | 0.0604 | 1 |
Brugia malayi | PAS domain containing protein | 0.0401 | 0.21 | 0.5195 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0133 | 0.0646 | 0.0498 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0028 | 0.0075 | 0.0162 |
Echinococcus granulosus | twitchin | 0.0016 | 0.0007 | 0.0013 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0018 | 0.0038 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0018 | 0.0028 |
Trichomonas vaginalis | heat shock protein, putative | 0.0033 | 0.0102 | 0.0036 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0018 | 0.0038 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0043 | 0.0156 | 0.1405 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0018 | 0.0044 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0126 | 0.0604 | 0.9263 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0039 | 0.0135 | 0.0291 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0866 | 0.4626 | 1 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0202 | 0.1018 | 0.2209 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0126 | 0.0604 | 0.0455 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.1854 | 1 | 1 |
Schistosoma mansoni | carbonyl reductase | 0.0021 | 0.0033 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0862 | 0.4608 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0068 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0761 | 0.406 | 0.8812 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.0126 | 0.0604 | 0.0532 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0104 | 0.0487 | 0.0424 |
Loa Loa (eye worm) | hypothetical protein | 0.0758 | 0.4041 | 0.8771 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0018 | 0.0038 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0126 | 0.0604 | 0.0455 |
Schistosoma mansoni | coup transcription factor | 0.0018 | 0.0018 | 0.0028 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0104 | 0.0487 | 0.0424 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0133 | 0.0646 | 0.0498 |
Echinococcus multilocularis | neuroglian | 0.0016 | 0.0007 | 0.0013 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0018 | 0.0018 | 0.0028 |
Trichomonas vaginalis | hypothetical protein | 0.1854 | 1 | 1 |
Onchocerca volvulus | 0.0022 | 0.0039 | 0.0047 | |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0018 | 0.0018 | 0.0002 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0046 | 0.0171 | 0.1499 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0018 | 0.0038 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0018 | 0.0038 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0018 | 0.0038 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0046 | 0.0171 | 0.0096 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0046 | 0.0171 | 0.2339 |
Plasmodium falciparum | endoplasmin, putative | 0.0033 | 0.0102 | 0.0036 |
Onchocerca volvulus | 0.0862 | 0.4608 | 1 | |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0126 | 0.0604 | 0.1311 |
Wolbachia endosymbiont of Brugia malayi | acyl carrier protein | 0.0052 | 0.0204 | 0.005 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0133 | 0.0646 | 0.0498 |
Schistosoma mansoni | jun-related protein | 0.0068 | 0.0293 | 0.0469 |
Echinococcus multilocularis | endoplasmin | 0.0043 | 0.0156 | 0.0336 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0018 | 0.0038 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0133 | 0.0646 | 1 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0018 | 0.0022 | 0.0046 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0068 | 0.0147 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.0126 | 0.0604 | 0.0532 |
Leishmania major | heat shock protein 83-1 | 0.0046 | 0.0171 | 0.1673 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0018 | 0.0018 | 0.0038 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0133 | 0.0646 | 0.0575 |
Echinococcus granulosus | heat shock protein 90 | 0.0039 | 0.0135 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.0604 | 0.1311 |
Mycobacterium ulcerans | oxidoreductase | 0.0126 | 0.0604 | 0.0455 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0188 | 0.0945 | 0.2022 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0108 | 0.0506 | 0.1094 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0046 | 0.0171 | 0.2339 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0133 | 0.0646 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0068 | 0.0169 |
Echinococcus granulosus | jun protein | 0.0084 | 0.0379 | 0.0818 |
Echinococcus granulosus | PP-binding domain containing protein | 0.0038 | 0.0129 | 0.0278 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0126 | 0.0604 | 0.0455 |
Trichomonas vaginalis | endoplasmin, putative | 0.0033 | 0.0102 | 0.0036 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0018 | 0.0038 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.0126 | 0.0604 | 0.0455 |
Schistosoma mansoni | acyl carrier protein | 0.0052 | 0.0204 | 0.0327 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0068 | 0.0147 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0104 | 0.0487 | 0.7444 |
Schistosoma mansoni | netrin receptor unc5 | 0.0018 | 0.0022 | 0.0034 |
Leishmania major | protein kinase, putative | 0.0104 | 0.0487 | 0.7222 |
Mycobacterium tuberculosis | Meromycolate extension acyl carrier protein AcpM | 0.0052 | 0.0204 | 0.005 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0126 | 0.0604 | 0.1305 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0068 | 0.0147 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.1854 | 1 | 1 |
Mycobacterium leprae | Possible regulatory protein | 0.0104 | 0.0487 | 0.0363 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.0844 | 0.1353 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0075 | 0.0327 | 0.0524 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.0171 | 0.1499 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0018 | 0.0018 | 0.0038 |
Schistosoma mansoni | lamin | 0.0027 | 0.0068 | 0.0109 |
Trypanosoma brucei | heat shock protein, putative | 0.0046 | 0.0171 | 0.1499 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0068 | 0.0147 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0021 | 0.0033 | 0.0071 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0126 | 0.0604 | 0.9263 |
Brugia malayi | MH2 domain containing protein | 0.012 | 0.0572 | 0.1414 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0126 | 0.0604 | 0.0455 |
Onchocerca volvulus | 0.0027 | 0.0068 | 0.0112 | |
Echinococcus granulosus | roundabout 2 | 0.002 | 0.0029 | 0.0061 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.0126 | 0.0604 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0018 | 0.0038 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0126 | 0.0604 | 0.0455 |
Brugia malayi | hypothetical protein | 0.0075 | 0.0327 | 0.081 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0018 | 0.0044 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0028 | 0.0075 | 0.0162 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0126 | 0.0604 | 0.0455 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0028 | 0.0075 | 0.0162 |
Trypanosoma cruzi | Acyl carrier protein, mitochondrial, putative | 0.0052 | 0.0204 | 0.288 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0691 | 0.368 | 0.7954 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0031 | 0.0087 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0068 | 0.0148 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0018 | 0.0038 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0691 | 0.368 | 0.7954 |
Onchocerca volvulus | 0.0133 | 0.0646 | 0.137 | |
Echinococcus granulosus | carbonyl reductase 1 | 0.0028 | 0.0075 | 0.0162 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.0126 | 0.0604 | 0.9247 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0126 | 0.0604 | 0.0455 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0018 | 0.0018 | 0.0002 |
Plasmodium vivax | acyl carrier protein, putative | 0.0052 | 0.0204 | 0.0118 |
Echinococcus granulosus | FTZ F1 alpha | 0.0018 | 0.0018 | 0.0038 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0126 | 0.0604 | 0.1494 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0018 | 0.0038 |
Trichomonas vaginalis | heat shock protein, putative | 0.0046 | 0.0171 | 0.0105 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.1854 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0104 | 0.0487 | 0.0424 |
Plasmodium vivax | heat shock protein 86, putative | 0.0046 | 0.0171 | 0.0085 |
Leishmania major | oxidoreductase-like protein | 0.0133 | 0.0646 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0018 | 0.0018 | 0.0038 |
Loa Loa (eye worm) | acyl carrier protein | 0.0052 | 0.0204 | 0.0444 |
Loa Loa (eye worm) | endoplasmin | 0.0046 | 0.0171 | 0.0371 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0018 | 0.0018 | 0.0044 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0018 | 0.0044 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0126 | 0.0604 | 0.9322 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0126 | 0.0604 | 0.0455 |
Mycobacterium leprae | POSSIBLE OXIDOREDUCTASE | 0.0126 | 0.0604 | 0.0481 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0068 | 0.0147 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0018 | 0.0018 | 0.0044 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0018 | 0.0018 | 0.0028 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0104 | 0.0487 | 0.0424 |
Treponema pallidum | acyl carrier protein | 0.0052 | 0.0204 | 1 |
Brugia malayi | bZIP transcription factor family protein | 0.0084 | 0.0379 | 0.0937 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0174 | 0.0867 | 0.0798 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0018 | 0.0018 | 0.0028 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0018 | 0.0038 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0046 | 0.0171 | 0.2339 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0021 | 0.0033 | 0.0071 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0018 | 0.0038 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0074 | 0.0322 | 0.0696 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0104 | 0.0487 | 0.7222 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0018 | 0.0018 | 0.0038 |
Leishmania major | heat shock protein, putative | 0.0031 | 0.0087 | 0.0205 |
Brugia malayi | nuclear hormone receptor | 0.0018 | 0.0018 | 0.0044 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0104 | 0.0487 | 0.0424 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0018 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0018 | 0.0038 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0018 | 0.0018 | 0.0038 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.0844 | 0.1353 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Relative potency (functional) | = 0.001 | In vitro ability of the compound to disrupt infectious activity of Eimeria sporozoites expressed as potency relative to frenolicin (B=1) | ChEMBL. | 9871641 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.