Detailed information for compound 425751

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 351.399 | Formula: C15H18FN5O2S
  • H donors: 2 H acceptors: 1 LogP: 1.53 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNC(=S)N/N=C\1/c2cc(F)ccc2N(C1=O)CN1CCOCC1
  • InChi: 1S/C15H18FN5O2S/c1-17-15(24)19-18-13-11-8-10(16)2-3-12(11)21(14(13)22)9-20-4-6-23-7-5-20/h2-3,8H,4-7,9H2,1H3,(H2,17,19,24)/b18-13-
  • InChiKey: ANVINTOYIMZOQS-AQTBWJFISA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0007 0.0006 0.0021
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0157 0.0261
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0007 0.0006 0.0021
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0008 0.0024 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0219 0.0364
Echinococcus granulosus cathepsin l1 0.0016 0.0127 0.0149
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.2778 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0152 0.0251
Loa Loa (eye worm) CYP4Cod1 0.0024 0.0223 0.0371
Trypanosoma brucei heat shock protein, putative 0.0032 0.0321 0.0533
Schistosoma mansoni immunophilin 0.0484 0.6043 0.7111
Echinococcus multilocularis 0.0007 0.0006 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0007 0.0006 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0157 0.0261
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0239 0.0397
Echinococcus granulosus cysteine protease 0.0008 0.0026 0.003
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0264 0.0438
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0264 0.031
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.008 0.0095
Echinococcus granulosus dnaJ subfamily B 0.0402 0.5004 0.5888
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0047 0.0514 0.0854
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0427 0.0709
Loa Loa (eye worm) hypothetical protein 0.0019 0.0154 0.0257
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0321 0.0534
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.0154 0.0257
Onchocerca volvulus 0.0027 0.0264 0.0916
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0047 0.0514 0.0855
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0239 0.0397
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0047 0.0514 0.0854
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0298 0.035
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0026 0.003
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.0042
Brugia malayi nuclear receptor RXR 0.0022 0.0199 0.0331
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0041 0.0437 0.0437
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0098 0.0162
Trypanosoma brucei heat shock protein, putative 0.0032 0.0321 0.0533
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0008 0.0024 0.0275
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0006 0.0001 0.0001
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.0154 0.0256
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0047 0.0514 0.0855
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0127 0.0211
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.0042
Echinococcus granulosus thyroid hormone receptor alpha 0.0022 0.0199 0.0235
Echinococcus multilocularis thyroid hormone receptor alpha 0.0171 0.2079 0.2079
Loa Loa (eye worm) hypothetical protein 0.0025 0.0233 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0026 0.0043
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0058 0.0095
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0008 0.0024 0.0039
Toxoplasma gondii exonuclease III APE 0.0018 0.0152 0.1817
Echinococcus granulosus heat shock protein 90 0.0025 0.0239 0.0281
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0303 0.0504
Leishmania major DNA polymerase kappa, putative 0.0021 0.0179 0.0297
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0007 0.0006 0.0009
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0219 0.0363
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0047 0.0514 0.0605
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0026 0.0043
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0362 0.06
Loa Loa (eye worm) hypothetical protein 0.0025 0.0233 0.0388
Brugia malayi nuclear receptor NHR-88 0.0022 0.0199 0.0331
Brugia malayi cytochrome P450 0.0007 0.0006 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0154 0.0257
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0366 0.0609
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0427 0.0709
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0007 0.0006 0.0021
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0047 0.0514 0.0605
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0264 0.0264
Onchocerca volvulus 0.0016 0.0127 0.044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0007 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0047 0.0514 0.0855
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0007 0.0006 0.0009
Trypanosoma brucei heat shock protein, putative 0.0032 0.0321 0.0533
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0332
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0427 0.0709
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0127 0.0211
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0157 0.0185
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0007 0.0006 0.0009
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0157 0.0157
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0542 0.09
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0254 0.0422
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0072 0.0837 0.1391
Trypanosoma cruzi heat shock protein, putative 0.0013 0.0084 0.0138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0475 0.079
Brugia malayi Cathepsin L-like precursor 0.0016 0.0127 0.0211
Loa Loa (eye worm) hypothetical protein 0.0009 0.0036 0.006
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0006 0.0001 0.0001
Brugia malayi orphan nuclear receptor NR2E1 0.0022 0.0199 0.0331
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0007 0.0006 0.0009
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.0239 0.0281
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0514 0.0514
Brugia malayi CXXC zinc finger family protein 0.0028 0.0276 0.0458
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0264 0.0917
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0254 0.0422
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0182 0.0301
Schistosoma mansoni pyruvate dehydrogenase 0.0006 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.0514 0.0854
Schistosoma mansoni ferritin 0.0008 0.0024 0.0028
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0008 0.0024 0.0275
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0127 0.0127
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0127 0.0211
Onchocerca volvulus 0.0035 0.0366 0.1274
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0072 0.0837 0.0985
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0712 0.1183
Toxoplasma gondii ABC1 family protein 0.0035 0.0366 0.4374
Loa Loa (eye worm) hypothetical protein 0.0011 0.0058 0.0096
Mycobacterium ulcerans hypothetical protein 0.0035 0.0366 0.0608
Onchocerca volvulus Bile acid receptor homolog 0.0047 0.0514 0.1788
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0098 0.0163
Brugia malayi nuclear receptor NHR-88 0.0047 0.0514 0.0854
Plasmodium vivax unspecified product 0.0008 0.0026 0.0042
Trichomonas vaginalis immunophilin, putative 0.0481 0.6014 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0154 0.1838
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0152 0.0548
Entamoeba histolytica hypothetical protein 0.0008 0.0024 0.0039
Mycobacterium ulcerans bacterioferritin BfrA 0.0008 0.0024 0.0038
Leishmania major cathepsin L-like protease 0.0016 0.0127 0.021
Loa Loa (eye worm) hypothetical protein 0.0047 0.0514 0.0855
Loa Loa (eye worm) hypothetical protein 0.0047 0.0514 0.0855
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0047 0.0514 0.0605
Trichomonas vaginalis sensor histidine kinase, putative 0.0006 0.0001 0.0001
Leishmania major cathepsin L-like protease 0.0063 0.0712 0.1183
Loa Loa (eye worm) beta-lactamase 0.0035 0.0366 0.0609
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0411 0.5125 0.6031
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0072 0.0837 1
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.0321 0.0533
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0047 0.0514 0.0855
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0366 0.0609
Brugia malayi hypothetical protein 0.0027 0.0264 0.0438
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0008 0.0026 0.0042
Schistosoma mansoni steroid hormone receptor ad4bp 0.0047 0.0514 0.0605
Entamoeba histolytica hypothetical protein 0.0019 0.0157 0.0259
Brugia malayi conserved hypotetical protein 0.0022 0.0199 0.0331
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0484 0.6043 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0366 0.0366
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0248 0.0412
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.008 0.008
Leishmania major hypothetical protein, conserved 0.0035 0.0366 0.0608
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0007 0.0006 0.0009
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0007 0.0006 0.0009
Brugia malayi Hsp90 protein 0.0013 0.0084 0.0139
Schistosoma mansoni hypothetical protein 0.0332 0.4123 0.4851
Trypanosoma cruzi DNA polymerase eta, putative 0.0014 0.0098 0.0162
Schistosoma mansoni hypothetical protein 0.0332 0.4123 0.4851
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0041 0.0437 0.0726
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0072 0.0837 0.139
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0043 0.0043
Toxoplasma gondii FATC domain-containing protein 0.0008 0.0024 0.0278
Trypanosoma brucei cytochrome P450, putative 0.0024 0.0223 0.037
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0006 0.0001 0.0001
Echinococcus multilocularis ferritin 0.0008 0.0024 0.0024
Echinococcus granulosus cathepsin L 0.0008 0.0026 0.003
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0007 0.0006 0.0009
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0007 0.0006 0.0009
Plasmodium vivax splicing factor 3B subunit 3, putative 0.0027 0.0264 0.0437
Trichomonas vaginalis ferritin, putative 0.0008 0.0024 0.0039
Mycobacterium tuberculosis Probable two component sensor kinase 0.0006 0.0001 0.0001
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0009 0.0036 0.0422
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0041 0.0069
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0837 0.1391
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0006 0.0001 0.0001
Brugia malayi photoreceptor-specific nuclear receptor 0.0047 0.0514 0.0854
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0041 0.0437 0.0723
Loa Loa (eye worm) hypothetical protein 0.0035 0.0366 0.0609
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0047 0.0514 0.0855
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0025 0.0239 0.2852
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0475 0.0789
Onchocerca volvulus 0.003 0.0298 0.1035
Entamoeba histolytica protein kinase rad3, putative 0.0008 0.0024 0.0039
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0014 0.0098 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0024 0.004
Brugia malayi Cytochrome P450 family protein 0.0007 0.0006 0.001
Toxoplasma gondii Hsp90 domain-containing protein 0.0013 0.0084 0.0992
Leishmania major serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0041 0.0437 0.0726
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.1484 0.1484
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0332
Brugia malayi Papain family cysteine protease containing protein 0.0008 0.0026 0.0043
Schistosoma mansoni endoplasmin 0.0032 0.0321 0.0378
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0251 0.0417
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.0042
Echinococcus multilocularis agrin 0.0019 0.0154 0.0154
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0251 0.0417
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Onchocerca volvulus 0.0022 0.0199 0.0693
Trichomonas vaginalis esterase, putative 0.0035 0.0366 0.0609
Loa Loa (eye worm) hypothetical protein 0.0072 0.0837 0.1391
Onchocerca volvulus 0.0026 0.0254 0.0882
Brugia malayi hypothetical protein 0.0019 0.0157 0.0261
Loa Loa (eye worm) nuclear hormone receptor 0.0022 0.0199 0.0332
Schistosoma mansoni hypothetical protein 0.0007 0.0006 0.0007
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0007 0.0006 0.0009
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0264 0.0438
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.0514 0.0854
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0006 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0332 0.0553
Trichomonas vaginalis heat shock protein, putative 0.0013 0.0084 0.0139
Onchocerca volvulus 0.0016 0.0127 0.044
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0041 0.0437 0.0514
Brugia malayi ecdysteroid receptor 0.0047 0.0514 0.0854
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0264 0.0439
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.0042
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0007 0.0006 0.0009
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0006 0.0001 0.0001
Plasmodium vivax heat shock protein, putative 0.0013 0.0084 0.0138
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0127 0.0127
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0199 0.0199
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0007 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0011 0.0058 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0361 0.06
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0157 0.0185
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0041 0.0437 0.0723
Brugia malayi cathepsin L-like precursor 0.0011 0.0058 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0124 0.0205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0041 0.0437 0.0514
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0154 0.0256
Schistosoma mansoni protein phosphatase-2b 0.0041 0.0437 0.0514
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0276 0.0458
Mycobacterium tuberculosis Conserved protein 0.0035 0.0366 0.1317
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0006 0.0001 0.0001
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0127 0.0211
Schistosoma mansoni terminal deoxycytidyl transferase 0.0014 0.0098 0.0115
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0127 0.0127
Leishmania major DNA polymerase eta, putative 0.0014 0.0098 0.0162
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0006 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0019 0.0157 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0047 0.0514 0.0854
Brugia malayi nuclear hormone receptor 0.0022 0.0199 0.0331
Plasmodium vivax vivapain-1 0.0008 0.0026 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0475 0.079
Echinococcus multilocularis follistatin 0.0019 0.0154 0.0154
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0481 0.6014 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0047 0.0514 0.0514
Echinococcus granulosus splicing factor 3b subunit 3 0.0027 0.0264 0.031
Brugia malayi Cathepsin L-like precursor 0.0011 0.0058 0.0096
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0321 0.0533
Schistosoma mansoni nuclear receptor 0.0022 0.0199 0.0235
Schistosoma mansoni hypothetical protein 0.0124 0.1484 0.1746
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0321 0.3831
Echinococcus granulosus follistatin 0.0019 0.0154 0.0182
Echinococcus multilocularis expressed protein 0.0019 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0332
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0366 0.0608
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0157 0.0261
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0007 0.0006 0.0009
Brugia malayi nuclear hormone receptor family member nhr-6 0.0022 0.0199 0.0331
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0152 0.0254
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0394 0.0654
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0105 0.0174
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0179 0.0645
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0025 0.0233 0.0274
Schistosoma mansoni immunophilin 0.0484 0.6043 0.7111
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0157 0.0185
Echinococcus granulosus expressed protein 0.0366 0.4559 0.5365
Echinococcus multilocularis heat shock protein 90 0.0032 0.0321 0.0321
Loa Loa (eye worm) hypothetical protein 0.0013 0.008 0.0134
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0475 0.079
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0006 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0366 0.0609
Schistosoma mansoni zinc finger protein 0.0022 0.0199 0.0235
Loa Loa (eye worm) hypothetical protein 0.0027 0.0264 0.0438
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0105 0.0174
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0712 0.1183
Brugia malayi PXA domain containing protein 0.0019 0.0157 0.0261
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0298 0.0298
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0264 0.0438
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.0042
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0157 0.0157
Trypanosoma brucei heat shock protein, putative 0.0032 0.0321 0.0533
Giardia lamblia Hypothetical protein 0.0072 0.0837 0.139
Loa Loa (eye worm) histone methyltransferase 0.001 0.0043 0.0071
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0072 0.0837 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0047 0.0514 0.1788
Loa Loa (eye worm) hypothetical protein 0.0025 0.0233 0.0388
Schistosoma mansoni cpg binding protein 0.0028 0.0276 0.0324
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Leishmania major serine/threonine protein phosphatase, putative 0.0041 0.0437 0.0726
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0366 0.0609
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0072 0.0837 0.139
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0025 0.0233 0.0274
Entamoeba histolytica cysteine proteinase 1, putative 0.0008 0.0026 0.0042
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0008 0.0026 0.0042
Loa Loa (eye worm) hypothetical protein 0.0006 0.0001 0.0001
Echinococcus granulosus FK506 binding protein 2 0.0113 0.1354 0.1593
Loa Loa (eye worm) cytochrome P450 0.0007 0.0006 0.001
Trypanosoma cruzi cysteine protease, putative 0.0008 0.0026 0.0042
Brugia malayi hypothetical protein 0.0022 0.0199 0.0331
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0475 0.0559
Leishmania major heat shock protein, putative 0.0013 0.0084 0.0138
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0292 0.0485
Echinococcus granulosus ferritin 0.0008 0.0024 0.0028
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0072 0.0837 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0264 0.0439
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0025 0.0239 0.2852
Trichomonas vaginalis fk506 binding protein, putative 0.0072 0.0837 0.1391
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0157 0.0185
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0047 0.0514 0.0605
Brugia malayi Nuclear hormone receptor-like 1 0.0047 0.0514 0.0854
Onchocerca volvulus 0.0016 0.0127 0.044
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0007 0.0006 0.0009
Trichomonas vaginalis spliceosomal protein sap, putative 0.0027 0.0264 0.0438
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0484 0.6043 1
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0072 0.0837 0.139
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0072 0.0837 0.139
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0047 0.0514 0.0605
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0007 0.0006 0.0021
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0022 0.0199 0.0332
Entamoeba histolytica cysteine proteinase 2 0.0008 0.0026 0.0042
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0475 0.0475
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0475 0.0789
Loa Loa (eye worm) hypothetical protein 0.004 0.043 0.0715
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0127 0.044
Echinococcus granulosus geminin 0.0332 0.4123 0.4851
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0021 0.0021
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0105 0.0124
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0006 0.0001 0.0001
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0026 0.003
Trichomonas vaginalis endoplasmin, putative 0.0019 0.0165 0.0275
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0481 0.6014 1
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0321 0.0533
Onchocerca volvulus 0.0022 0.0199 0.0693
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0712 0.1183
Entamoeba histolytica cysteine protease, putative 0.0016 0.0127 0.0209
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0712 0.1183
Loa Loa (eye worm) hypothetical protein 0.0047 0.0514 0.0855
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0041 0.0437 0.0726
Plasmodium vivax vivapain-3 0.0008 0.0026 0.0042
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0366 0.1317
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0427 0.071
Echinococcus multilocularis heat shock protein 0.0032 0.0321 0.0321
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0332 0.0553
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0712 0.1183
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0366 0.0431
Loa Loa (eye worm) hypothetical protein 0.0047 0.0514 0.0855
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0427 0.0709
Loa Loa (eye worm) hypothetical protein 0.0041 0.0437 0.0727
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0105 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0157 0.0185
Loa Loa (eye worm) FKBP5 protein 0.0481 0.6014 1
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0105 0.0124
Loa Loa (eye worm) hypothetical protein 0.0027 0.0264 0.0439
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0254 0.0422
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0124 0.0205
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0157 0.0185
Onchocerca volvulus 0.0027 0.0264 0.0917
Brugia malayi Cathepsin L-like precursor 0.0016 0.0127 0.0211
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0006 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0124 0.0205
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0007 0.0006 0.0021
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0157 0.0185
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0127 0.0211
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0152 0.0253
Loa Loa (eye worm) ctsf protein 0.0016 0.0127 0.0211
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0127 0.0211
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0481 0.6014 0.7077
Echinococcus granulosus endoplasmin 0.0025 0.0239 0.0281
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0157 0.0157
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0072 0.0837 0.1384
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0157 0.0261
Echinococcus granulosus cpg binding protein 0.003 0.0296 0.0348
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0332 0.0553
Echinococcus multilocularis microtubule associated protein 2 0.0677 0.8498 0.8498
Loa Loa (eye worm) cysteine protease 0.0016 0.0127 0.0211
Brugia malayi hypothetical protein 0.0025 0.0233 0.0387
Loa Loa (eye worm) hypothetical protein 0.0008 0.0024 0.004
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0006 0.0001 0.0001
Leishmania major cytochrome p450-like protein 0.0007 0.0006 0.0009
Schistosoma mansoni cpg binding protein 0.003 0.0296 0.0348
Brugia malayi Nuclear hormone receptor E75 0.0022 0.0199 0.0331
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0072 0.0837 1
Mycobacterium tuberculosis Conserved protein 0.0035 0.0366 0.1317
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0072 0.0837 0.139
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0068 0.0113
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.0042
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0014 0.0098 0.0115
Schistosoma mansoni nuclear receptor 0.0022 0.0199 0.0235
Onchocerca volvulus 0.0011 0.0058 0.02
Schistosoma mansoni apoferritin-2 0.0008 0.0024 0.0028
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0027 0.0264 0.0439
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0127 0.021
Loa Loa (eye worm) heat shock protein 75 0.0013 0.0084 0.0139
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0264 0.0917
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0007 0.0006 0.0021
Echinococcus multilocularis 0.0113 0.1354 0.1354
Schistosoma mansoni heat shock protein 0.0032 0.0321 0.0378
Echinococcus multilocularis cathepsin L 0.0008 0.0026 0.0026
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0321 0.0534
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0006 0.0001 0.0001
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0007 0.0006 0.0009
Brugia malayi Probable DNA topoisomerase II 0.0006 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0019 0.0157 0.0259
Schistosoma mansoni thyroid hormone receptor 0.0171 0.2079 0.2447
Brugia malayi Cytochrome P450 family protein 0.0024 0.0223 0.0371
Echinococcus multilocularis cysteine protease 0.0016 0.0127 0.0127
Echinococcus multilocularis serine protein kinase ATM 0.0008 0.0024 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0712 0.1183
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0152 0.0253
Loa Loa (eye worm) hypothetical protein 0.0019 0.0157 0.0261
Leishmania major cathepsin L-like protease 0.0063 0.0712 0.1183
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0481 0.6014 1
Echinococcus multilocularis dna polymerase eta 0.0014 0.0098 0.0098
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Trichomonas vaginalis heat shock protein, putative 0.0019 0.0165 0.0275
Schistosoma mansoni DNA polymerase eta 0.0014 0.0098 0.0115
Echinococcus multilocularis geminin 0.0332 0.4123 0.4123
Trypanosoma brucei heat shock protein, putative 0.0032 0.0321 0.0533
Mycobacterium ulcerans hypothetical protein 0.0113 0.1354 0.2251
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0157 0.0261
Trichomonas vaginalis receptor histidine kinase, putative 0.0006 0.0001 0.0001
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0475 0.0789
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0072 0.0837 1
Schistosoma mansoni ferritin light chain 0.0008 0.0024 0.0028
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0025 0.0239 0.0859
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0298 0.035
Brugia malayi nuclear hormone receptor family member odr-7 0.0022 0.0199 0.0331
Schistosoma mansoni heat shock protein 0.0032 0.0321 0.0378
Schistosoma mansoni intermediate filament proteins 0.0026 0.0254 0.0299
Mycobacterium tuberculosis Possible two component sensor kinase 0.0006 0.0001 0.0001
Schistosoma mansoni organic anion transporter 0.0027 0.0264 0.031
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0481 0.6014 0.7077
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0157 0.0157
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0127 0.044
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0152 0.0179
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0223 0.0371
Loa Loa (eye worm) hypothetical protein 0.0019 0.0154 0.0257
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0127 0.044
Echinococcus multilocularis cpg binding protein 0.003 0.0296 0.0296
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0105 0.0175
Echinococcus granulosus dna polymerase eta 0.0014 0.0098 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0105 0.0175
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0179 0.0297
Schistosoma mansoni cpg binding protein 0.003 0.0296 0.0348
Echinococcus granulosus cathepsin l1 0.0011 0.0058 0.0068
Loa Loa (eye worm) nuclear receptor NHR-67 0.0022 0.0199 0.0332
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0127 0.0149
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0013 0.0084 0.0137
Schistosoma mansoni lamin 0.0026 0.0254 0.0299
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0427 0.0709
Echinococcus granulosus heat shock protein 90 0.0032 0.0321 0.0378
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0113 0.1354 0.2251
Schistosoma mansoni ferritin 0.0008 0.0024 0.0028
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0223 0.037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0712 0.1183
Brugia malayi steroid hormone receptor 0.0047 0.0514 0.0854
Echinococcus multilocularis FTZ F1 alpha 0.0047 0.0514 0.0514
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0251 0.0417
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0152 0.0253
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0321 0.0533
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0007 0.0006 0.0009
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0007 0.0006 0.0009
Schistosoma mansoni fk506 binding protein 0.0072 0.0837 0.0985
Mycobacterium ulcerans heat shock protein 90 0.0025 0.0239 0.0396
Loa Loa (eye worm) hypothetical protein 0.0035 0.0366 0.0609
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0411 0.5125 0.5125
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0321 0.3831
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0152 0.0253
Loa Loa (eye worm) endoplasmin 0.0032 0.0321 0.0534
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0366 0.1317
Echinococcus multilocularis cysteine protease 0.0016 0.0127 0.0127
Treponema pallidum heat shock protein 90 0.0025 0.0239 0.0396
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0157 0.0261
Trypanosoma cruzi cysteine proteinase, putative 0.0008 0.0026 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0047 0.0514 0.0855
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0008 0.0024 0.0039
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.0199 0.0693
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0219 0.0363
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0332
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0321 0.0533
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0427 0.0709
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0021 0.0025
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0152 0.0253
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0007 0.0006 0.0021
Plasmodium vivax vivapain-2 0.0016 0.0127 0.021
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0072 0.0837 1
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0007 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0154 0.0257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0332 0.0553
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0157 0.0261
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0007 0.0006 0.0009
Onchocerca volvulus 0.0073 0.0844 0.2936
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0427 0.0709
Toxoplasma gondii protease inhibitor PI2 0.0019 0.0154 0.1838
Schistosoma mansoni ferritin 0.0008 0.0024 0.0028
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0021 0.0025
Schistosoma mansoni ferritin 0.0008 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0332
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0481 0.6014 1
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.0042
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0157 0.0185
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0007 0.0006 0.0021
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0022 0.0199 0.0331
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0481 0.6014 1
Schistosoma mansoni cytochrome P450 0.0007 0.0006 0.0007
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0157 0.0185
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0007 0.0006 0.0021
Plasmodium vivax SET domain protein, putative 0.003 0.0298 0.0494
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0481 0.6014 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0157 0.0157
Echinococcus granulosus lamin 0.0026 0.0254 0.0299
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.0042
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0152 0.0253
Mycobacterium leprae Probable lipase LipE 0.0035 0.0366 0.4374
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0154 0.1838
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0156 0.0259
Echinococcus multilocularis endoplasmin 0.0025 0.0239 0.0239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0332 0.0553
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0837 0.1391
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0233 0.0387
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0127 0.0211
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0427 0.0709
Trypanosoma brucei heat shock protein, putative 0.0032 0.0321 0.0533
Schistosoma mansoni immunophilin 0.0411 0.5125 0.6031
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0427 0.0709
Loa Loa (eye worm) hypothetical protein 0.0014 0.0098 0.0163
Schistosoma mansoni coup transcription factor 0.0047 0.0514 0.0605
Echinococcus multilocularis lamin dm0 0.0026 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0026 0.0248 0.0412
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0127 0.021
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0047 0.0514 0.0605
Brugia malayi Papain family cysteine protease containing protein 0.0008 0.0026 0.0043
Brugia malayi Cathepsin L-like precursor 0.0016 0.0127 0.0211
Echinococcus granulosus agrin 0.0019 0.0154 0.0182
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0514 0.0605
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0332
Leishmania major cytochrome p450-like protein 0.0024 0.0223 0.037
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0043 0.005
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0047 0.0514 0.0854
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0157 0.0261
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0105 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0157 0.0261
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0154 0.1838
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0321 0.0533
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0007 0.0006 0.0009
Brugia malayi hypothetical protein 0.0025 0.0233 0.0387
Loa Loa (eye worm) hypothetical protein 0.0026 0.0254 0.0422
Brugia malayi polk-prov protein 0.003 0.0303 0.0504
Brugia malayi ecdysone receptor 0.0022 0.0199 0.0331
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0481 0.6014 1
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0239 0.0396
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0264 0.0438
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0113 0.1354 0.2251
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0484 0.6043 0.6043
Onchocerca volvulus 0.0019 0.0154 0.0535
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0127 0.0149
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0427 0.0709
Brugia malayi Cathepsin L-like precursor 0.0016 0.0127 0.0211
Brugia malayi Endoplasmin precursor 0.0032 0.0321 0.0533
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.2514 0.418
Schistosoma mansoni ap endonuclease 0.0018 0.0152 0.0179
Echinococcus multilocularis nuclear receptor nhr 48 0.0022 0.0199 0.0199
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0008 0.0024 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0058 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0219 0.0364
Loa Loa (eye worm) hypothetical protein 0.0019 0.0154 0.0257
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Brugia malayi Cathepsin L-like precursor 0.0011 0.0058 0.0096
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0152 0.0253
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0113 0.1354 0.224
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0014 0.0098 0.0163
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0264 0.0264
Toxoplasma gondii cathepsin CPL 0.0016 0.0127 0.151
Brugia malayi Cytochrome P450 family protein 0.0024 0.0223 0.0371
Loa Loa (eye worm) hypothetical protein 0.0035 0.0366 0.0609
Mycobacterium ulcerans lipase LipD 0.0035 0.0366 0.0608
Loa Loa (eye worm) hypothetical protein 0.0025 0.0233 0.0388
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.0042
Onchocerca volvulus 0.0027 0.0264 0.0917
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0127 0.0127
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0481 0.6014 1
Onchocerca volvulus 0.0027 0.0264 0.0917
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0013 0.0084 0.0098
Brugia malayi nuclear receptor RXR 0.0025 0.0233 0.0387
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0366 0.4374
Onchocerca volvulus 0.0016 0.0127 0.044
Schistosoma mansoni hypothetical protein 0.0051 0.0559 0.0658
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.0199 0.0235
Brugia malayi Cathepsin L-like precursor 0.0016 0.0127 0.0211
Schistosoma mansoni ap endonuclease 0.0018 0.0152 0.0179
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0007 0.0006 0.0021
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0157 0.0261
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0157 0.0185
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0481 0.6014 0.9989
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0298 0.035
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0127 0.0149
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0006 0.0001 0.0001
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0427 0.0709
Trichomonas vaginalis DNA topoisomerase II, putative 0.0006 0.0001 0.0001
Entamoeba histolytica CPSF A subunit region protein, putative 0.0027 0.0264 0.0435
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0157 0.0261
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0026 0.0042
Onchocerca volvulus 0.0027 0.0264 0.0917
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0006 0.0001 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0298 0.035
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0366 0.1317
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0179 0.0297
Mycobacterium ulcerans bacterioferritin BfrB 0.0008 0.0024 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0127 0.0211
Trypanosoma cruzi serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0041 0.0437 0.0726
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0127 0.021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0298 0.035
Brugia malayi Serine/threonine protein phosphatase 2B catalytic subunit 2 0.0041 0.0437 0.0726
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0008 0.0024 0.0028
Brugia malayi hypothetical protein 0.0027 0.0264 0.0438
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0127 0.0211
Giardia lamblia DINP protein human, muc B family 0.0021 0.0179 0.0297
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0047 0.0514 0.0514
Loa Loa (eye worm) hypothetical protein 0.0027 0.0264 0.0439
Brugia malayi intermediate filament protein 0.0026 0.0254 0.0422
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0609 0.7274
Loa Loa (eye worm) hypothetical protein 0.0047 0.0514 0.0855
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0075 0.0866 0.0866
Trypanosoma brucei heat shock protein, putative 0.0032 0.0321 0.0533
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0026 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0366 0.0608
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0643 0.1068
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0332
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0157 0.0261
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Toxoplasma gondii cytochrome p450 superfamily protein 0.0007 0.0006 0.0068
Echinococcus granulosus serine protein kinase ATM 0.0008 0.0024 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0127 0.0211
Trichomonas vaginalis fk506-binding protein, putative 0.0481 0.6014 1
Onchocerca volvulus 0.0072 0.0837 0.2913
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0041 0.0437 0.0723
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0712 0.1183
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0481 0.6014 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0362 0.06
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.0514 0.0854
Onchocerca volvulus 0.0016 0.0127 0.044
Brugia malayi Steroid receptor seven-up type 2 0.0047 0.0514 0.0854
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0332 0.0553
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0072 0.0837 0.139
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Loa Loa (eye worm) hypothetical protein 0.0016 0.0127 0.0211
Echinococcus multilocularis heat shock protein 90 0.0025 0.0239 0.0239
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0366 0.1317
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0157 0.0261
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0008 0.0024 0.0039
Plasmodium vivax endoplasmin, putative 0.0032 0.0321 0.0533
Echinococcus granulosus cytochrome P450 2K1 0.0007 0.0006 0.0007
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0072 0.0837 0.139
Loa Loa (eye worm) cytochrome P450 family protein 0.0007 0.0006 0.001
Schistosoma mansoni protein phosphatase-2b 0.0041 0.0437 0.0514
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0006 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0427 0.0709
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0105 0.0175
Echinococcus multilocularis musashi 0.0026 0.0254 0.0254
Brugia malayi nuclear receptor NHR-67 0.0022 0.0199 0.0331
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.1484 0.1746
Toxoplasma gondii transporter, major facilitator family protein 0.0027 0.0264 0.3147
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0008 0.0024 0.0024
Brugia malayi prostaglandin transporter 0.0027 0.0264 0.0438
Trypanosoma brucei unspecified product 0.001 0.0042 0.0069
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0157 0.0157
Schistosoma mansoni ferritin light chain 0.0008 0.0024 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0427 0.0709
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0157 0.0261
Brugia malayi heat shock protein 90 0.0032 0.0321 0.0533
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0332
Loa Loa (eye worm) fibroinase 0.0016 0.0127 0.0211
Echinococcus granulosus heat shock protein 0.0032 0.0321 0.0378
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0345 0.0573
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0157 0.0185
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0105 0.0175
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0007 0.0006 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0157 0.0157
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.0199 0.0235
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.0514 0.0854
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0058 0.0068
Mycobacterium leprae Conserved hypothetical protein 0.0007 0.0006 0.0068
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0006 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0157 0.0261
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0332 0.3968
Loa Loa (eye worm) hypothetical protein 0.0409 0.5103 0.8485
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0058 0.0096
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0264 0.0917
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0366 0.0609
Loa Loa (eye worm) hypothetical protein 0.0019 0.0157 0.0261
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0481 0.6014 1
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0366 0.0608
Echinococcus granulosus dna polymerase kappa 0.004 0.0427 0.0502
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0514 0.0605
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0475 0.0785
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0321 0.0533
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0481 0.6014 1
Giardia lamblia Grp94/Hsp90 0.0025 0.0239 0.0396
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0154 0.0256
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.0514 0.0854
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0321 0.0533
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0321 0.053
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0041 0.0437 0.0723
Mycobacterium tuberculosis Conserved protein 0.0035 0.0366 0.1317
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0157 0.0261
Trypanosoma brucei unspecified product 0.001 0.0042 0.0069
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0007 0.0006 0.0021
Loa Loa (eye worm) hypothetical protein 0.0012 0.0074 0.0124
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0366 0.0608
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0152 0.0254
Brugia malayi kinase, mitochondrial precursor 0.0006 0.0001 0.0001
Trichomonas vaginalis fk506-binding protein, putative 0.0072 0.0837 0.1391
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0105 0.0175
Leishmania major cathepsin L-like protease 0.0063 0.0712 0.1183
Trypanosoma brucei heat shock protein 84, putative 0.0013 0.0084 0.0138
Trichomonas vaginalis set domain proteins, putative 0.0233 0.2871 0.4775
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0712 0.1183
Schistosoma mansoni fkbp-rapamycin associated protein 0.0008 0.0024 0.0028
Plasmodium falciparum heat shock protein 90, putative 0.0013 0.0084 0.0138
Brugia malayi Nuclear hormone receptor E75 0.0022 0.0199 0.0331
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0154 0.0256
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0006 0.0001 0.0001
Schistosoma mansoni RAR-like nuclear receptor 0.0047 0.0514 0.0605
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0152 0.0253
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.015 0.0248
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0366 0.1317
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.0199 0.0199
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0022 0.0199 0.0199
Echinococcus granulosus cathepsin L cysteine protease 0.0008 0.0026 0.003
Echinococcus multilocularis ecdysone induced protein 78C 0.0047 0.0514 0.0514
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0157 0.0185
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0514 0.0514
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0481 0.6014 1
Brugia malayi hypothetical protein 0.0019 0.0157 0.0261
Mycobacterium tuberculosis Conserved hypothetical protein 0.0014 0.0098 0.0351
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0366 0.1317
Echinococcus granulosus FTZ F1 alpha 0.0047 0.0514 0.0605
Echinococcus granulosus intermediate filament protein 0.0026 0.0254 0.0299
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0022 0.0199 0.0235
Schistosoma mansoni thyroid hormone receptor 0.0171 0.2079 0.2447
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0321 0.0533
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0007 0.0006 0.0009
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0072 0.0837 0.1391
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0152 0.1817
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0127 0.021
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0127 0.0209
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0361 0.06
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0022 0.0199 0.0235
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0022 0.0199 0.0199
Brugia malayi beta-lactamase family protein 0.0035 0.0366 0.0608
Plasmodium falciparum cysteine proteinase falcipain 1 0.0008 0.0026 0.0042
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0007 0.0006 0.0021
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0113 0.1354 0.2251
Trypanosoma cruzi cysteine proteinase, putative 0.0008 0.0026 0.0042
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.069 0.0812
Loa Loa (eye worm) hypothetical protein 0.0025 0.0233 0.0388
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0047 0.0514 0.0605
Onchocerca volvulus 0.0047 0.0514 0.1788
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0427 0.071
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.0199 0.0199
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0223 0.037
Schistosoma mansoni agrin 0.0019 0.0154 0.0182
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0332 0.0553
Schistosoma mansoni DNA topoisomerase II 0.0006 0.0001 0.0001
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0321 0.0533
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0007 0.0006 0.0009
Onchocerca volvulus 0.0035 0.0366 0.1274
Onchocerca volvulus 0.0028 0.0276 0.0958
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0154 0.1838
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0041 0.0437 0.0723
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0366 0.0608
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0072 0.0837 0.139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0475 0.079
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0127 0.0211
Schistosoma mansoni apoferritin-2 0.0008 0.0024 0.0028
Schistosoma mansoni heat shock protein 0.0013 0.0084 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0427 0.0709
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0072 0.0837 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Echinococcus multilocularis expressed protein 0.0366 0.4559 0.4559
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0105 0.0174
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0113 0.1354 0.2251
Echinococcus multilocularis dna polymerase kappa 0.004 0.0427 0.0427
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0047 0.0514 0.0854
Loa Loa (eye worm) hypothetical protein 0.0009 0.0032 0.0053
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0157 0.0185
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0007 0.0006 0.0021
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0366 0.0608
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0239 0.0397
Trypanosoma brucei unspecified product 0.0034 0.0345 0.0573
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0006 0.0001 0.0001
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0072 0.0837 0.139
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0321 0.053
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0157 0.0261
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0007 0.0006 0.0021
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0362 0.06
Trypanosoma brucei heat shock protein, putative 0.0032 0.0321 0.0533
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0157 0.0185
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0157 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0047 0.0514 0.0854
Loa Loa (eye worm) TOPoisomerase family member 0.0006 0.0001 0.0001
Schistosoma mansoni lamin 0.0026 0.0254 0.0299
Leishmania major peptidylprolyl isomerase-like protein 0.0481 0.6014 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0475 0.0789
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0366 0.0608
Onchocerca volvulus 0.0233 0.2871 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0157 0.0185
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0006 0.0001 0.0001
Schistosoma mansoni follistatin 0.0019 0.0154 0.0182
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0366 0.1317
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0475 0.0785
Plasmodium falciparum endoplasmin, putative 0.0019 0.0165 0.0274
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0105 0.0175
Brugia malayi Pre-SET motif family protein 0.003 0.0298 0.0494
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.0223 0.037
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0199 0.0235
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0047 0.0514 0.0855
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0013 0.0084 0.0084
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0157 0.0185
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0332
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0036 0.006
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0007 0.0006 0.0021
Echinococcus granulosus lamin dm0 0.0026 0.0254 0.0299
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.0042
Loa Loa (eye worm) hypothetical protein 0.0006 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0712 0.1183
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0157 0.0157
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0157 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0047 0.0514 0.0854
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0157 0.0261
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0298 0.3552
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0072 0.0837 0.139
Leishmania major cytochrome p450-like protein 0.0007 0.0006 0.0009
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0007 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0264 0.0439
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0157 0.0261
Brugia malayi tailless protein 0.0022 0.0199 0.0331
Echinococcus multilocularis fk506 binding protein 0.0481 0.6014 0.6014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0248 0.0412
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0007 0.0006 0.0021
Onchocerca volvulus 0.0026 0.0254 0.0882
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0239 0.0396
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0481 0.6014 1
Loa Loa (eye worm) steroid hormone receptor 0.0047 0.0514 0.0855
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0298 0.0298
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0041 0.0437 0.0437
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0199 0.0235
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0475 0.0789
Schistosoma mansoni microtubule-associated protein tau 0.0677 0.8498 1
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0007 0.0006 0.0009
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0427 0.0709
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0008 0.0026 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Onchocerca volvulus 0.0035 0.0366 0.1274
Loa Loa (eye worm) DR-78 0.0022 0.0199 0.0332
Loa Loa (eye worm) hypothetical protein 0.0017 0.0136 0.0225
Mycobacterium ulcerans beta-lactamase 0.0035 0.0366 0.0608
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0366 0.0609
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0152 0.0254
Brugia malayi nuclear hormone receptor 0.0047 0.0514 0.0854
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0024 0.004
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0008 0.0024 0.0084
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Toxoplasma gondii heat shock protein 75, putative 0.0013 0.0084 0.0992
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0712 0.1183
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0072 0.0837 0.3011
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0157 0.0185
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0157 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0361 0.06
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0047 0.0514 0.0605
Echinococcus granulosus expressed protein 0.0008 0.0024 0.0028
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0072 0.0837 0.139
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0264 0.031
Loa Loa (eye worm) hypothetical protein 0.0047 0.0514 0.0855
Leishmania major cathepsin L-like protease 0.0016 0.0127 0.021
Leishmania major fk506-binding protein 1-like protein 0.0481 0.6014 1
Brugia malayi Pre-SET motif family protein 0.0205 0.2514 0.4175
Onchocerca volvulus 0.0016 0.0127 0.044
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0484 0.6043 0.7111
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0072 0.0837 0.139
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0047 0.0514 0.0514
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0025 0.0239 0.0396
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0047 0.0514 0.0605
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0014 0.0098 0.0115
Onchocerca volvulus 0.0027 0.0264 0.0917
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0481 0.6014 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0105 0.0174
Treponema pallidum bacterioferrin (TpF1) 0.0008 0.0024 0.0038
Schistosoma mansoni retinoic acid receptor RXR 0.0047 0.0514 0.0605
Leishmania major cathepsin L-like protease 0.0016 0.0127 0.021
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0072 0.0837 0.139
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.0233 0.0274
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0514 0.0605
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0233 0.0387
Echinococcus granulosus ecdysone induced protein 78C 0.0047 0.0514 0.0605
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0024 0.004
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0006 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0047 0.0514 0.0855
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0366 0.0431
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0113 0.1354 0.2249
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0712 0.1183
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0152 0.0253
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0013 0.0084 0.0289
Trypanosoma brucei protein phosphatase 2B, putative 0.0041 0.0437 0.0726
Plasmodium falciparum splicing factor 3B subunit 3, putative 0.0027 0.0264 0.0437
Brugia malayi PXA domain containing protein 0.0019 0.0157 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0361 0.06
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0157 0.0261
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0047 0.0514 0.0514
Brugia malayi beta-lactamase family protein 0.0035 0.0366 0.0608
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0157 0.0185
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0475 0.0789
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.028 0.0465
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0482 0.6021 1
Schistosoma mansoni nuclear receptor nhr-48 0.0022 0.0199 0.0235
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0332
Entamoeba histolytica deoxycytidyl transferase, putative 0.0014 0.0098 0.0161
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0021 0.0025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0127 0.0211
Onchocerca volvulus 0.0016 0.0127 0.044
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0047 0.0514 0.0855
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0072 0.0837 0.139
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0025 0.0233 0.0233
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0366 0.0431
Loa Loa (eye worm) hypothetical protein 0.0027 0.0264 0.0439
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0712 0.1183
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0008 0.0024 0.004
Schistosoma mansoni hypothetical protein 0.0072 0.0837 0.0985
Plasmodium vivax vivapain-2 0.0016 0.0127 0.021
Schistosoma mansoni organic anion transporter 0.0027 0.0264 0.031
Brugia malayi beta-lactamase 0.0035 0.0366 0.0608
Giardia lamblia GTOR 0.0044 0.0475 0.0789
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0332
Trichomonas vaginalis fk506-binding protein, putative 0.0072 0.0837 0.1391
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0154 0.0256
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0008 0.0024 0.0028
Trypanosoma cruzi cysteine peptidase, putative 0.0008 0.0026 0.0042
Plasmodium falciparum serine/threonine protein phosphatase 2B catalytic subunit A 0.0041 0.0437 0.0726
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.0199 0.0693
Schistosoma mansoni endoplasmin 0.0032 0.0321 0.0378
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.0042
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0072 0.0837 0.139
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0098 0.0163
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0332
Echinococcus granulosus microtubule associated protein 2 0.0677 0.8498 1
Brugia malayi SPARC precursor 0.0019 0.0154 0.0256
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0223 0.0371
Toxoplasma gondii splicing factor 3b, subunit 3, putative 0.0027 0.0264 0.3146
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0127 0.021
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0072 0.0837 0.139
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0007 0.0006 0.0021
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0366 0.0609
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0276 0.0325
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0007 0.0006 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0219 0.0363
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0712 0.1183
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0157 0.0157
Onchocerca volvulus Protein ultraspiracle homolog 0.0047 0.0514 0.1788
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0105 0.0174
Loa Loa (eye worm) hypothetical protein 0.003 0.0303 0.0504
Plasmodium vivax serine/threonine protein phosphatase 2B catalytic subunit A, putative 0.0041 0.0437 0.0726
Loa Loa (eye worm) hypothetical protein 0.0035 0.0366 0.0609
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0127 0.0211
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0022 0.0199 0.0235
Brugia malayi Cytochrome P450 family protein 0.0007 0.0006 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0219 0.0364
Leishmania major cathepsin L-like protease 0.0016 0.0127 0.021
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Brugia malayi hypothetical protein 0.0022 0.0199 0.0331
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.0042
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0475 0.0559
Loa Loa (eye worm) hypothetical protein 0.0022 0.0199 0.0332
Plasmodium falciparum heat shock protein 90, putative 0.0013 0.0084 0.0138
Loa Loa (eye worm) hypothetical protein 0.0019 0.0157 0.0261
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0127 0.0209
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0361 0.06
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.0042
Loa Loa (eye worm) hypothetical protein 0.0006 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0219 0.0364
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0837 0.139
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0006 0.0001 0.0001
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.0239 0.0396
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0712 0.1183
Loa Loa (eye worm) hypothetical protein 0.0011 0.0058 0.0096
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0199 0.0235
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0127 0.0211
Echinococcus multilocularis expressed protein 0.0008 0.0024 0.0024
Plasmodium falciparum heat shock protein 90 0.0032 0.0321 0.0533
Echinococcus multilocularis lamin 0.0026 0.0254 0.0254
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0127 0.0211
Schistosoma mansoni hypothetical protein 0.0402 0.5004 0.5888
Toxoplasma gondii protein phosphatase 2B catalytic subunit, calcineurin family phosphatse superfamily protein 0.0041 0.0437 0.5221
Mycobacterium tuberculosis Conserved protein 0.0006 0.0001 0.0001
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0152 0.0253
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0427 0.0709
Echinococcus granulosus nuclear receptor nhr 48 0.0022 0.0199 0.0235
Loa Loa (eye worm) hypothetical protein 0.0035 0.0366 0.0609
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0127 0.0149
Leishmania major heat shock protein 83-1 0.0032 0.0321 0.0533
Loa Loa (eye worm) hypothetical protein 0.003 0.0298 0.0495
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0427 0.0709
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0157 0.0185
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0157 0.0185
Plasmodium vivax heat shock protein 90, putative 0.0013 0.0084 0.0138
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0011 0.0056 0.0662
Trypanosoma brucei DNA polymerase eta, putative 0.0014 0.0098 0.0162
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0041 0.0437 0.0723
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0006 0.0001 0.0001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0008 0.0024 0.004
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0072 0.0837 1
Brugia malayi splicing factor 3B subunit 3 0.0027 0.0264 0.0438
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0025 0.0233 0.0388
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0098 0.0162
Loa Loa (eye worm) hypothetical protein 0.0019 0.0157 0.0261
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0047 0.0514 0.0605
Trichomonas vaginalis receptor histidine kinase, putative 0.0006 0.0001 0.0001
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.5004 0.5004
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0303 0.0504
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0007 0.0006 0.0009
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0047 0.0514 0.0605
Brugia malayi Cathepsin L-like precursor 0.0016 0.0127 0.0211
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0157 0.0185
Entamoeba histolytica cysteine protease, putative 0.0008 0.0026 0.0042
Leishmania major cathepsin L-like protease 0.0016 0.0127 0.021
Mycobacterium leprae putative cytochrome p450 0.0007 0.0006 0.0068
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.0514 0.0854
Echinococcus multilocularis splicing factor 3b subunit 3 0.0027 0.0264 0.0264
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0475 0.0789
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0481 0.6014 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0058 0.0096
Loa Loa (eye worm) hypothetical protein 0.0027 0.0264 0.0439

Activities

Activity type Activity value Assay description Source Reference
GI (functional) = 12 % Growth inhibition of Mycobacterium tuberculosis H37Rv at 6.25 ug/mL by microplate alamar blue assay ChEMBL. 17561405
GI (functional) = 12 % Growth inhibition of Mycobacterium tuberculosis H37Rv at 6.25 ug/mL by microplate alamar blue assay ChEMBL. 17561405

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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