Detailed information for compound 426109

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 462.733 | Formula: C30H42N2S
  • H donors: 2 H acceptors: 0 LogP: 7.73 Rotable bonds: 18
    Rule of 5 violations (Lipinski): 1
  • SMILES: C(CCCCc1ccc(s1)CCCCNCc1ccccc1)CCCNCc1ccccc1
  • InChi: 1S/C30H42N2S/c1(2-4-13-23-31-25-27-15-7-5-8-16-27)3-11-19-29-21-22-30(33-29)20-12-14-24-32-26-28-17-9-6-10-18-28/h5-10,15-18,21-22,31-32H,1-4,11-14,19-20,23-26H2
  • InChiKey: HLJGJYAZSUBZNW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0047 0.0173
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0163 0.2258
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.008 0.0647 0.0986
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0043 0.0225 0.0225
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0236 0.0485
Echinococcus multilocularis sodium and chloride dependent glycine 0.0035 0.013 0.013
Trichomonas vaginalis abcb9, putative 0.0043 0.0225 0.0818
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.0199
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0114 0.1029 0.1029
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Echinococcus multilocularis somatostatin receptor 0.0028 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.008 0.0647 0.0986
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0073 0.0562 0.5462
Leishmania major calcium-transporting ATPase, putative 0.006 0.0413 0.3059
Wolbachia endosymbiont of Brugia malayi DNA polymerase III alpha subunit 0.0239 0.2433 0.5
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0028 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.006 0.0413 0.0413
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0028 0.0061 0.0093
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.005 0.0309 0.2294
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0073 0.0562 0.2047
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0042 0.0212 0.0323
Schistosoma mansoni growth hormone secretagogue receptor 0.0028 0.0061 0.0125
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0171 0.1661 0.3407
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0043 0.0226 0.1672
Echinococcus granulosus intermediate filament protein 0.006 0.0421 0.0863
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0086 0.0711 0.6908
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.005 0.0299 0.0379
Brugia malayi Cathepsin L-like precursor 0.0037 0.0163 0.0248
Schistosoma mansoni cpg binding protein 0.0034 0.0122 0.025
Brugia malayi ecdysteroid receptor 0.0171 0.1661 0.2532
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0043 0.0226 0.1672
Brugia malayi Cathepsin L-like precursor 0.0025 0.0023 0.0036
Plasmodium vivax P-type ATPase4, putative 0.0099 0.0851 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0171 0.1661 0.1661
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0028 0.006 0.0217
Leishmania major cathepsin L-like protease 0.0143 0.1349 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0028 0.0061 0.0093
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0042 0.0212 0.0323
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0043 0.0225 0.046
Echinococcus granulosus tumor protein p63 0.038 0.4016 0.8236
Brugia malayi hypothetical protein 0.0028 0.0061 0.0093
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0073 0.0562 0.7788
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0048 0.0174
Trichomonas vaginalis abcb9, putative 0.0043 0.0225 0.0818
Brugia malayi hypothetical protein 0.0028 0.0061 0.0093
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0043 0.0225 0.0225
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0086 0.0711 0.2589
Trypanosoma cruzi P-type H+-ATPase, putative 0.0032 0.0099 0.0737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0122 0.0445
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0061 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0171 0.1661 0.2532
Schistosoma mansoni survival motor neuron protein 0.0034 0.0118 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0226 0.0824
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0036
Echinococcus granulosus death domain containing protein 0.0032 0.0103 0.0212
Brugia malayi hypoxia-induced factor 1 0.0337 0.3536 0.5389
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0193 0.0703
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0171 0.1661 0.3407
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0061 0.0125
Echinococcus multilocularis Nuclear hormone receptor HR96 0.008 0.0647 0.0647
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0042 0.0212 0.0435
Entamoeba histolytica P-glyco protein 6, putative 0.0043 0.0225 0.3112
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0438 0.5146
Brugia malayi multidrug resistance protein 3 0.0043 0.0225 0.0342
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0084 0.0687 0.1409
Onchocerca volvulus 0.0034 0.0118 0.0348
Loa Loa (eye worm) hypothetical protein 0.0171 0.1661 0.2532
Loa Loa (eye worm) hypothetical protein 0.0042 0.0217 0.0331
Loa Loa (eye worm) hypothetical protein 0.0023 0.0004 0.0006
Giardia lamblia Multidrug resistance-associated protein 1 0.0042 0.0218 0.2122
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0171 0.1661 0.1661
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0061 0.0061
Brugia malayi neuropeptide F receptor 0.0028 0.0061 0.0093
Schistosoma mansoni neuropeptide receptor 0.0028 0.0061 0.0125
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0061 0.0125
Schistosoma mansoni nAChR subunit 0.0042 0.0212 0.0435
Loa Loa (eye worm) serotonin transporter b 0.0204 0.2035 0.3102
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0025 0.0026 0.0053
Leishmania major p-glycoprotein e 0.0043 0.0226 0.1672
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0047 0.0173
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0029 0.0065 0.0485
Echinococcus granulosus tachykinin peptides receptor 99D 0.0028 0.0061 0.0125
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0061 0.0061
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0028 0.0061 0.0093
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0029 0.0065 0.0485
Brugia malayi nuclear hormone receptor 0.0171 0.1661 0.2532
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.006 0.0413 0.3059
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Echinococcus multilocularis lamin dm0 0.006 0.0421 0.0421
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0042 0.0212 0.0212
Leishmania major trypanothione reductase 0.0053 0.0339 0.2514
Schistosoma mansoni hypothetical protein 0.0034 0.0118 0.0242
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0035 0.013 0.0199
Onchocerca volvulus 0.0028 0.0061 0.0139
Onchocerca volvulus 0.0042 0.0212 0.0693
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.032 0.0655
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.0386 0.0791
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0163 0.0593
Loa Loa (eye worm) cysteine protease 0.0037 0.0163 0.0248
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Brugia malayi ABC transporter family protein 0.0043 0.0225 0.0342
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0042 0.0212 0.0435
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0043 0.0225 0.0818
Onchocerca volvulus 0.0028 0.0061 0.0139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Echinococcus multilocularis cysteine protease 0.0037 0.0163 0.0163
Plasmodium falciparum amino acid transporter, putative 0.0035 0.013 0.1532
Entamoeba histolytica ABC transporter, putative 0.0043 0.0226 0.3127
Trypanosoma brucei protein kinase, putative 0.0057 0.0386 0.2858
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0035 0.013 0.0267
Toxoplasma gondii target of rapamycin (TOR), putative 0.0038 0.0164 0.1924
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0025 0.0026 0.0026
Echinococcus granulosus dro:myosuppressin receptor 0.0028 0.0061 0.0125
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0287 0.2971 0.4529
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Echinococcus granulosus G protein coupled receptor 139 0.0028 0.0061 0.0125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0163 0.0593
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0028 0.0061 0.0061
Schistosoma mansoni amine GPCR 0.0028 0.0061 0.0125
Echinococcus multilocularis neuropeptide s receptor 0.0028 0.0061 0.0061
Trichomonas vaginalis cation-transporting ATPase, putative 0.0097 0.0836 0.3046
Schistosoma mansoni coup transcription factor 0.0171 0.1661 0.3407
Echinococcus multilocularis cpg binding protein 0.0034 0.0122 0.0122
Brugia malayi E1-E2 ATPase family protein 0.0048 0.0278 0.0424
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.032 0.032
Brugia malayi intermediate filament protein 0.006 0.0421 0.0641
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0386 0.2858
Plasmodium vivax multidrug resistance protein 1, putative 0.0043 0.0225 0.2639
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0056 0.0372 0.0566
Onchocerca volvulus 0.0037 0.0163 0.0512
Loa Loa (eye worm) hypoxia-induced factor 1 0.0337 0.3536 0.5389
Onchocerca volvulus 0.0028 0.0061 0.0139
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0073 0.0562 0.2047
Schistosoma mansoni nAChR subunit 0.0042 0.0212 0.0435
Echinococcus granulosus serotonin transporter 0.0204 0.2035 0.4174
Echinococcus granulosus lamin 0.006 0.0421 0.0863
Brugia malayi photoreceptor-specific nuclear receptor 0.0171 0.1661 0.2532
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Echinococcus multilocularis cysteine protease 0.0037 0.0163 0.0163
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0042 0.0212 0.0435
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0042 0.0212 0.0323
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0086 0.0711 0.1458
Echinococcus granulosus cathepsin l1 0.0025 0.0023 0.0048
Schistosoma mansoni patched 1 0.0037 0.0162 0.0332
Schistosoma mansoni hypothetical protein 0.0255 0.2611 0.5354
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0061 0.0061
Plasmodium falciparum thioredoxin reductase 0.0053 0.0339 0.3986
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0163 0.0593
Giardia lamblia GTOR 0.005 0.0309 0.3007
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.008 0.0647 0.2288
Echinococcus multilocularis ecdysone induced protein 78C 0.0171 0.1661 0.1661
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0164 0.0596
Brugia malayi hypothetical protein 0.0108 0.0961 0.1465
Brugia malayi tailless protein 0.008 0.0647 0.0986
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0086 0.0711 0.1083
Loa Loa (eye worm) hypothetical protein 0.0171 0.1661 0.2532
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0164 0.0596
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Mycobacterium tuberculosis Probable reductase 0.0121 0.1105 0.1404
Loa Loa (eye worm) hypothetical protein 0.009 0.0755 0.1151
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0126 0.0259
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0028 0.0061 0.0139
Echinococcus granulosus single minded 2 0.0081 0.0648 0.133
Echinococcus multilocularis calcium transporting atpase 0.0084 0.0687 0.0687
Echinococcus multilocularis musashi 0.006 0.0421 0.0421
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Schistosoma mansoni intermediate filament proteins 0.006 0.0421 0.0863
Loa Loa (eye worm) hypothetical protein 0.0171 0.1661 0.2532
Trichomonas vaginalis ABC transporter, putative 0.0043 0.0225 0.0818
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0035 0.013 0.1532
Echinococcus granulosus netrin receptor unc 5 0.0032 0.0103 0.0212
Loa Loa (eye worm) hypothetical protein 0.0081 0.0656 0.0999
Schistosoma mansoni nuclear hormone receptor 0.0171 0.1661 0.3407
Schistosoma mansoni steroid hormone receptor ad4bp 0.0171 0.1661 0.3407
Brugia malayi Death domain containing protein 0.0032 0.0103 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0048 0.0174
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0037 0.0163 0.0163
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0043 0.0225 0.046
Schistosoma mansoni sodium/chloride dependent transporter 0.0035 0.0136 0.0279
Loa Loa (eye worm) hypothetical protein 0.0043 0.0226 0.0344
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.0386 0.2858
Echinococcus granulosus FTZ F1 alpha 0.0171 0.1661 0.3407
Echinococcus granulosus sterol regulatory element binding protein 0.0037 0.0162 0.0332
Leishmania major P-type H -ATPase, putative 0.0046 0.0263 0.1952
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0077 0.0281
Onchocerca volvulus 0.008 0.0647 0.2288
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0722 0.7872 1
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0061 0.0125
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0043 0.0225 0.2639
Brugia malayi putative neuropeptide receptor 0.0028 0.0061 0.0093
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.0386 0.2858
Echinococcus granulosus cathepsin L cysteine proteinase 0.0037 0.0163 0.0334
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Echinococcus multilocularis orexin receptor type 2 0.0028 0.0061 0.0061
Brugia malayi Cathepsin L-like precursor 0.0037 0.0163 0.0248
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0025 0.0022 0.0162
Schistosoma mansoni retinoic acid receptor RXR 0.028 0.2899 0.5946
Brugia malayi RNA recognition motif domain containing protein 0.0044 0.0236 0.036
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Loa Loa (eye worm) thioredoxin reductase 0.0053 0.0339 0.0517
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0042 0.0212 0.0323
Trypanosoma cruzi target of rapamycin kinase 3 0.004 0.0194 0.1435
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0061 0.0125
Brugia malayi Cathepsin L-like precursor 0.0037 0.0163 0.0248
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Brugia malayi Cation transporter family protein 0.0042 0.0212 0.0323
Plasmodium vivax vivapain-2 0.0037 0.0163 0.1915
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0028 0.0061 0.0125
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0042 0.0212 0.0212
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0032 0.0103 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0171 0.1661 0.2532
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.0199
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0061 0.0125
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0061 0.0125
Echinococcus granulosus multidrug resistance protein 1 0.0043 0.0225 0.046
Brugia malayi Dopamine receptor 0.0028 0.0061 0.0093
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0035 0.013 0.013
Onchocerca volvulus 0.0028 0.0061 0.0139
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0061 0.0061
Schistosoma mansoni RAR-like nuclear receptor 0.0171 0.1661 0.3407
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0099 0.0851 0.1081
Brugia malayi TAR-binding protein 0.0044 0.0236 0.036
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0171 0.1661 0.3407
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.008 0.0647 0.1327
Loa Loa (eye worm) RNA binding protein 0.0044 0.0236 0.036
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0386 0.1404
Loa Loa (eye worm) hypothetical protein 0.009 0.0755 0.1151
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0164 0.0596
Brugia malayi hypothetical protein 0.0056 0.0376 0.0573
Schistosoma mansoni cpg binding protein 0.0032 0.0101 0.0208
Echinococcus granulosus neuropeptide receptor A26 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0042 0.0212 0.0323
Echinococcus granulosus sodium and chloride dependent glycine 0.0035 0.013 0.0267
Echinococcus granulosus ecdysone induced protein 78C 0.0171 0.1661 0.3407
Trypanosoma cruzi hypothetical protein 0.0025 0.0017 0.0125
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.006 0.0413 0.0846
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0339 0.2514
Echinococcus granulosus peptide allatostatin:somatostatin 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0163 0.0593
Echinococcus multilocularis serotonin receptor 0.0028 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0043 0.0225 0.0342
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0171 0.1661 0.601
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.0386 0.0791
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.0105 0.016
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0043 0.0225 0.0818
Loa Loa (eye worm) hypothetical protein 0.009 0.0755 0.1151
Brugia malayi hypothetical protein 0.0081 0.0648 0.0987
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0204 0.2035 0.4174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Loa Loa (eye worm) hypothetical protein 0.0097 0.0836 0.1274
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0029 0.0065 0.0485
Schistosoma mansoni hypothetical protein 0.0268 0.2754 0.5649
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0163 0.0593
Echinococcus granulosus sex peptide receptor 0.0028 0.0061 0.0125
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0042 0.0217 0.0446
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0126 0.0259
Echinococcus multilocularis G-protein coupled receptor, putative 0.0028 0.0061 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0171 0.1661 0.2532
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0171 0.1661 0.3407
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0074 0.0577 0.0577
Brugia malayi hypothetical protein 0.0028 0.0061 0.0093
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.014 0.1321 0.271
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0036
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0042 0.0212 0.0435
Leishmania major cathepsin L-like protease 0.0143 0.1349 1
Brugia malayi Na,K-ATPase alpha subunit 0.0129 0.1193 0.1818
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0061 0.0093
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0163 0.0593
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Plasmodium falciparum glutathione reductase 0.0053 0.0339 0.3986
Loa Loa (eye worm) hypothetical protein 0.0494 0.5299 0.8077
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0061 0.0125
Onchocerca volvulus Cathepsin F homolog 0.0037 0.0163 0.0512
Loa Loa (eye worm) hypothetical protein 0.0029 0.0069 0.0105
Brugia malayi hypothetical protein 0.009 0.0755 0.1151
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0386 0.1404
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0032 0.0099 0.0151
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0171 0.1661 0.3407
Brugia malayi Thioredoxin reductase 0.0053 0.0339 0.0517
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0028 0.006 0.0091
Leishmania major P-type H -ATPase, putative 0.0046 0.0263 0.1952
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0171 0.1661 0.2532
Entamoeba histolytica hypothetical protein 0.0081 0.0648 0.8977
Toxoplasma gondii isocitrate dehydrogenase 0.0025 0.0022 0.0257
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0061 0.0061
Onchocerca volvulus 0.0028 0.0061 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0061 0.0125
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.004 0.0194 0.1435
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0086 0.0711 0.5269
Entamoeba histolytica cysteine proteinase, putative 0.0025 0.0023 0.0324
Schistosoma mansoni cathepsin F (C01 family) 0.0037 0.0163 0.0334
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0025 0.0022 0.0028
Plasmodium vivax vivapain-2 0.0037 0.0163 0.1915
Echinococcus multilocularis Niemann Pick C1 protein 0.0087 0.0722 0.0722
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0043 0.0226 0.1672
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0061 0.0061
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.0386 0.0386
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0035 0.013 0.0267
Brugia malayi Cathepsin L-like precursor 0.0025 0.0023 0.0036
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0035 0.013 0.1532
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0086 0.0711 0.5269
Brugia malayi hypothetical protein 0.008 0.0647 0.0986
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0042 0.0212 0.0323
Echinococcus granulosus survival motor neuron protein 1 0.0164 0.1591 0.3263
Trypanosoma brucei trypanothione reductase 0.0053 0.0339 0.2514
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.006 0.0217
Schistosoma mansoni biogenic amine receptor 0.0028 0.0061 0.0125
Brugia malayi Uncoordinated protein 44 0.0032 0.0103 0.0157
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0061 0.0125
Schistosoma mansoni hypothetical protein 0.0036 0.0147 0.03
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0061 0.0125
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0043 0.0225 0.0818
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0163 0.2258
Brugia malayi G protein-coupled receptor F59B2.13 0.0028 0.0061 0.0093
Onchocerca volvulus 0.0028 0.0061 0.0139
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0081 0.0648 0.1328
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0042 0.0212 0.0212
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0024 0.0015 0.0202
Mycobacterium tuberculosis Conserved hypothetical protein 0.0045 0.025 0.0318
Onchocerca volvulus 0.0028 0.0061 0.0139
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0043 0.0225 0.0818
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0061 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Loa Loa (eye worm) hypothetical protein 0.0606 0.6561 1
Brugia malayi Pre-SET motif family protein 0.0234 0.2382 0.363
Onchocerca volvulus 0.0043 0.0225 0.0738
Echinococcus granulosus Nuclear hormone receptor HR96 0.008 0.0647 0.1327
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0061 0.0125
Entamoeba histolytica P-glycoprotein-5 0.0043 0.0225 0.3112
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0035 0.013 0.0199
Echinococcus multilocularis lamin 0.006 0.0421 0.0421
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.009 0.0755 0.1549
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0061 0.0061
Leishmania major calcium motive p-type ATPase, putative 0.006 0.0413 0.3059
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Onchocerca volvulus 0.0204 0.2035 0.7382
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0042 0.0212 0.0323
Trichomonas vaginalis taga, putative 0.0043 0.0225 0.0818
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0042 0.0212 0.0323
Schistosoma mansoni multidrug resistance protein 0.0043 0.0226 0.0463
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0061 0.0125
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0043 0.0225 0.0342
Brugia malayi nuclear receptor NHR-88 0.008 0.0647 0.0986
Trypanosoma cruzi cysteine peptidase, putative 0.0143 0.1349 1
Schistosoma mansoni nAChR subunit 0.0042 0.0212 0.0435
Schistosoma mansoni multidrug resistance protein 0.0043 0.0226 0.0463
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.009 0.0755 0.1549
Plasmodium vivax SET domain protein, putative 0.0034 0.0126 0.1486
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0042 0.0212 0.0323
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0028 0.0061 0.0061
Plasmodium vivax amine transporter, putative 0.0035 0.013 0.1532
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0099 0.0851 0.1745
Schistosoma mansoni hypothetical protein 0.0268 0.2754 0.5649
Onchocerca volvulus 0.0056 0.0367 0.1259
Trichomonas vaginalis cation-transporting ATPase, putative 0.0073 0.0562 0.2047
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0043 0.0225 0.046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0037 0.0163 0.0163
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0037 0.0162 0.0246
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0073 0.0562 0.4166
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0028 0.006 0.006
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0061 0.0125
Onchocerca volvulus 0.0032 0.0101 0.0286
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0025 0.0022 0.0162
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0061 0.0125
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0376 0.4422
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0035 0.013 0.0267
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0035 0.013 0.0267
Schistosoma mansoni hypothetical protein 0.0028 0.0061 0.0125
Schistosoma mansoni ankyrin 23/unc44 0.0032 0.0103 0.0212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0143 0.1349 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0171 0.1661 0.2532
Echinococcus granulosus g-protein coupled receptor 0.0028 0.0061 0.0125
Schistosoma mansoni myosin xvIII 0.0028 0.0061 0.0125
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0028 0.006 0.0122
Leishmania major ABC-thiol transporter 0.0043 0.0226 0.1672
Leishmania major protein kinase, putative 0.0029 0.0065 0.0485
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0032 0.0099 0.0737
Brugia malayi hypothetical protein 0.0028 0.0061 0.0093
Brugia malayi Dopamine receptor protein 1 0.0028 0.0061 0.0093
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0035 0.013 0.0199
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0081 0.0648 0.0648
Schistosoma mansoni sodium/chloride dependent transporter 0.0204 0.2035 0.4174
Trypanosoma brucei calcium-transporting ATPase, putative 0.0036 0.0149 0.1106
Brugia malayi Serotonin receptor 0.0028 0.0061 0.0093
Brugia malayi Nuclear hormone receptor-like 1 0.0171 0.1661 0.2532
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0204 0.2035 0.3102
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0088 0.0737 0.1511
Loa Loa (eye worm) fibroinase 0.0037 0.0163 0.0248
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0126 0.1486
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0061 0.0061
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0035 0.013 0.0267
Brugia malayi PAS domain containing protein 0.0109 0.0967 0.1474
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.008 0.0647 0.0986
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0376 0.2789
Loa Loa (eye worm) hypothetical protein 0.0025 0.0023 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0081 0.0294
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0042 0.0212 0.0435
Schistosoma mansoni multidrug resistance protein 0.0043 0.0226 0.0463
Schistosoma mansoni hypothetical protein 0.0456 0.4876 1
Schistosoma mansoni hypothetical protein 0.014 0.1321 0.271
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Loa Loa (eye worm) hypothetical protein 0.008 0.0647 0.0986
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.005 0.0309 0.0635
Toxoplasma gondii P-type ATPase4, putative 0.0074 0.0577 0.6776
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0061 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Plasmodium falciparum transporter, putative 0.0035 0.013 0.1532
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0073 0.0562 0.4166
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0086 0.0711 0.5269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0047 0.0173
Loa Loa (eye worm) ACC-1 protein 0.0042 0.0212 0.0323
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0061 0.0061
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.005 0.0309 0.2294
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0043 0.0225 0.0818
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0037 0.0163 0.1915
Echinococcus granulosus nuclear receptor 2DBD gamma 0.008 0.0647 0.1327
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.005 0.0309 0.0309
Echinococcus granulosus g protein coupled receptor 0.0028 0.0061 0.0125
Giardia lamblia Multidrug resistance-associated protein 1 0.0043 0.0226 0.2193
Loa Loa (eye worm) hypothetical protein 0.0043 0.0225 0.0342
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0171 0.1661 0.2532
Brugia malayi putative neuropeptide receptor NPR1 0.0028 0.0061 0.0093
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0376 0.2789
Echinococcus multilocularis survival motor neuron protein 1 0.0164 0.1591 0.1591
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0028 0.0061 0.0125
Brugia malayi Dopamine receptor protein 2 0.0028 0.0061 0.0093
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0028 0.0061 0.0093
Brugia malayi MH2 domain containing protein 0.0189 0.1864 0.2841
Echinococcus multilocularis allatostatin A receptor 0.0028 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.009 0.0755 0.1151
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0036 0.0149 0.1106
Onchocerca volvulus 0.0035 0.013 0.0392
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0043 0.0225 0.0818
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0037 0.0163 0.0248
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.005 0.0309 0.0472
Brugia malayi Intermediate filament tail domain containing protein 0.006 0.0421 0.0641
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0101 0.0155
Echinococcus granulosus hypothetical protein 0.0028 0.0061 0.0125
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0025 0.0022 0.0045
Echinococcus granulosus ubiquitin specific protease 41 0.0086 0.0711 0.1458
Toxoplasma gondii hypothetical protein 0.0035 0.013 0.1532
Leishmania major cathepsin L-like protease 0.0037 0.0163 0.1208
Loa Loa (eye worm) hypothetical protein 0.008 0.0647 0.0986
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.0386 0.3747
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.0105 0.016
Loa Loa (eye worm) hypothetical protein 0.0108 0.0961 0.1465
Schistosoma mansoni ATPase 0.0097 0.0836 0.1715
Loa Loa (eye worm) E1-E2 ATPase 0.0046 0.0263 0.0401
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0028 0.0061 0.0093
Echinococcus granulosus somatostatin receptor 0.0028 0.0061 0.0125
Onchocerca volvulus 0.0037 0.0163 0.0512
Echinococcus multilocularis netrin receptor unc 5 0.0032 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.0199
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0041 0.0203 0.2819
Brugia malayi Nuclear hormone receptor-like 1 0.009 0.0755 0.1151
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0025 0.0022 0.0257
Schistosoma mansoni amine GPCR 0.0028 0.0061 0.0125
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0043 0.0225 0.046
Schistosoma mansoni neuropeptide receptor 0.0028 0.0061 0.0125
Brugia malayi RNA binding protein 0.0044 0.0236 0.036
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0043 0.0225 0.0818
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0386 0.1404
Echinococcus multilocularis thioredoxin glutathione reductase 0.0053 0.0339 0.0339
Echinococcus granulosus orexin receptor type 2 0.0028 0.0061 0.0125
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.005 0.0309 0.4288
Echinococcus multilocularis isocitrate dehydrogenase 0.0025 0.0022 0.0022
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0099 0.0851 1
Entamoeba histolytica P-glycoprotein-1 0.0043 0.0225 0.3112
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0084 0.0687 0.1047
Brugia malayi Cathepsin L-like precursor 0.0037 0.0163 0.0248
Schistosoma mansoni lamin 0.006 0.0421 0.0863
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Brugia malayi sulfakinin receptor protein 0.0028 0.0061 0.0093
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0042 0.0212 0.0323
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0171 0.1661 0.2532
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.032 0.032
Brugia malayi hypothetical protein 0.0164 0.1591 0.2425
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Onchocerca volvulus 0.0037 0.0163 0.0512
Brugia malayi Cathepsin L-like precursor 0.0037 0.0163 0.0248
Loa Loa (eye worm) isocitrate dehydrogenase 0.0025 0.0022 0.0033
Brugia malayi Serotonin receptor 0.0028 0.0061 0.0093
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0025 0.0022 0.0022
Schistosoma mansoni aryl hydrocarbon receptor 0.0109 0.0967 0.1983
Schistosoma mansoni amine GPCR 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Echinococcus multilocularis tar DNA binding protein 0.0044 0.0236 0.0236
Schistosoma mansoni smdr2 0.0043 0.0225 0.046
Schistosoma mansoni nuclear receptor 0.008 0.0647 0.1327
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0037 0.0163 0.1915
Brugia malayi hypothetical protein 0.0028 0.0061 0.0093
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0042 0.0218 0.3021
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0084 0.0687 0.1409
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.006 0.0441
Onchocerca volvulus 0.0028 0.0061 0.0139
Loa Loa (eye worm) glutathione reductase 0.0053 0.0339 0.0517
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0028 0.006 0.0217
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Onchocerca volvulus 0.0028 0.0061 0.0139
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0061 0.0125
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0121 0.1105 0.1404
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0061 0.0125
Schistosoma mansoni hypothetical protein 0.0025 0.0026 0.0053
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.008 0.0647 0.1327
Echinococcus multilocularis FTZ F1 alpha 0.0171 0.1661 0.1661
Mycobacterium leprae PROBABLE DNA POLYMERASE III (ALPHA CHAIN) DNAE1 (DNA NUCLEOTIDYLTRANSFERASE) 0.024 0.2446 0.3108
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0074 0.0577 0.21
Brugia malayi Steroid receptor seven-up type 2 0.0171 0.1661 0.2532
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0073 0.0562 0.7788
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0028 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0032 0.0106 0.0218
Leishmania major protein kinase, putative 0.0029 0.0065 0.0485
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0042 0.0212 0.0212
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.006 0.0217
Echinococcus granulosus neuropeptide s receptor 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0108 0.0961 0.1465
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0129 0.1193 0.1818
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0114 0.1029 0.211
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0035 0.013 0.0267
Loa Loa (eye worm) hypothetical protein 0.008 0.0647 0.0986
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Echinococcus multilocularis cathepsin L cysteine protease 0.0037 0.0163 0.0163
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0143 0.1349 1
Leishmania major calcium-translocating P-type ATPase 0.0097 0.0836 0.6199
Onchocerca volvulus 0.0034 0.0126 0.0378
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0061 0.0061
Echinococcus multilocularis geminin 0.0268 0.2754 0.2754
Echinococcus multilocularis multidrug resistance associated protein 7 0.0043 0.0226 0.0226
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0061 0.0125
Leishmania major cathepsin L-like protease 0.0143 0.1349 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0028 0.0061 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0126 0.0259
Brugia malayi Pre-SET motif family protein 0.0034 0.0126 0.0193
Onchocerca volvulus Neuropeptide F receptor homolog 0.0028 0.0061 0.0139
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0171 0.1661 0.3407
Loa Loa (eye worm) hypothetical protein 0.0171 0.1661 0.2532
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0163 0.1208
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.008 0.0647 0.0647
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0061 0.0093
Echinococcus granulosus fmrfamide receptor 0.0028 0.0061 0.0125
Brugia malayi Nuclear hormone receptor E75 0.008 0.0647 0.0986
Onchocerca volvulus 0.0028 0.0061 0.0139
Loa Loa (eye worm) hypothetical protein 0.006 0.0421 0.0641
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0042 0.0212 0.0435
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0042 0.0212 0.0435
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.032 0.0655
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0121 0.1105 0.1404
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0143 0.1349 1
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0236 0.0485
Brugia malayi Protein kinase domain containing protein 0.0033 0.0109 0.0166
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Trypanosoma brucei PAB1-binding protein , putative 0.0056 0.0376 0.2789
Loa Loa (eye worm) melatonin receptor type 1A 0.0028 0.0061 0.0093
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0236 0.0485
Echinococcus granulosus nAChR subunit 0.0042 0.0212 0.0435
Loa Loa (eye worm) hypothetical protein 0.0056 0.0367 0.0559
Loa Loa (eye worm) hypothetical protein 0.0036 0.0149 0.0227
Echinococcus multilocularis serotonin receptor 0.0028 0.0061 0.0061
Echinococcus multilocularis ubiquitin specific protease 41 0.0086 0.0711 0.0711
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0143 0.1349 1
Mycobacterium ulcerans error-prone DNA polymerase 0.0239 0.2433 0.309
Echinococcus multilocularis multidrug resistance protein 1 0.0025 0.0023 0.0023
Loa Loa (eye worm) calcium ATPase 0.0042 0.0218 0.0332
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0061 0.0125
Brugia malayi small heat shock protein 0.0606 0.6561 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0043 0.0226 0.2652
Echinococcus granulosus lamin dm0 0.006 0.0421 0.0863
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0061 0.0061
Brugia malayi hypothetical protein 0.0028 0.0061 0.0093
Echinococcus granulosus glycine receptor subunit alpha 1 0.0042 0.0212 0.0435
Brugia malayi hypothetical protein 0.0028 0.0061 0.0093
Schistosoma mansoni neuropeptide f receptor 76f 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.0199
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0028 0.0061 0.0061
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0043 0.0226 0.1672
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0172 0.0262
Loa Loa (eye worm) norepinephrine transporter 0.0204 0.2035 0.3102
Trichomonas vaginalis ABC transporter, putative 0.0043 0.0225 0.0818
Schistosoma mansoni opsin-like receptor 0.0028 0.0061 0.0125
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0073 0.0562 0.6605
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0043 0.0226 0.1672
Loa Loa (eye worm) hypothetical protein 0.0129 0.1193 0.1818
Echinococcus multilocularis transfer RNA-Lys 0.0081 0.0648 0.0648
Onchocerca volvulus Netrin receptor homolog 0.0032 0.0103 0.0293
Echinococcus multilocularis sodium and chloride dependent glycine 0.0035 0.013 0.013
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0042 0.0212 0.0323
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0386 0.2858
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0061 0.0061
Mycobacterium ulcerans hypothetical protein 0.0045 0.025 0.0318
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0032 0.0099 0.1168
Entamoeba histolytica P-glycoprotein-2 0.0043 0.0225 0.3112
Echinococcus multilocularis serotonin transporter 0.0204 0.2035 0.2035
Plasmodium falciparum multidrug resistance protein 1 0.0043 0.0225 0.2639
Schistosoma mansoni sodium/chloride dependent transporter 0.0035 0.013 0.0267
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0061 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0081 0.0294
Schistosoma mansoni netrin receptor unc5 0.0032 0.0103 0.0212
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0025 0.0022 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0126 0.0259
Schistosoma mansoni hypothetical protein 0.0058 0.039 0.08
Schistosoma mansoni multidrug resistance protein 0.0043 0.0225 0.046
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0035 0.013 0.013
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0086 0.0711 0.1458
Loa Loa (eye worm) hypothetical protein 0.0037 0.0162 0.0246
Schistosoma mansoni lamin 0.006 0.0421 0.0863
Loa Loa (eye worm) hypothetical protein 0.0043 0.0226 0.0344
Trypanosoma cruzi major cysteine proteinase, putative 0.0112 0.1005 0.7449
Loa Loa (eye worm) hypothetical protein 0.0038 0.0172 0.0262
Schistosoma mansoni neuropeptide receptor 0.0028 0.0061 0.0125
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.001 0.0072
Echinococcus granulosus 7tm_1 domain containing protein 0.0028 0.0061 0.0125
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0061 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0309 0.1127
Echinococcus granulosus cathepsin l1 0.0037 0.0163 0.0334
Echinococcus granulosus g protein coupled receptor 0.0028 0.0061 0.0125
Echinococcus granulosus Niemann Pick C1 protein 0.0087 0.0722 0.148
Chlamydia trachomatis DNA polymerase III subunit alpha 0.0239 0.2433 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0061 0.0125
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0236 0.0485
Entamoeba histolytica hypothetical protein 0.0043 0.0226 0.3127
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0025 0.0022 0.0162
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0171 0.1661 0.1661
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0035 0.013 0.0267
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0029 0.0065 0.0485
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0074 0.0577 0.1182
Brugia malayi CHE-14 protein 0.0037 0.0162 0.0246
Echinococcus granulosus nuclear receptor nhr 48 0.008 0.0647 0.1327
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0105 0.0215
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0073 0.0562 0.4166
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0171 0.1661 0.2532
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0043 0.0225 0.1664
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0061 0.0125
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0043 0.0225 0.0818
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0097 0.0836 0.0836
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0163 0.0512
Echinococcus granulosus glycine receptor subunit alpha 1 0.0042 0.0212 0.0435
Echinococcus granulosus multidrug resistance associated protein 1 0.0043 0.0226 0.0463
Loa Loa (eye worm) hypothetical protein 0.0032 0.0103 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0164 0.0596
Brugia malayi hypothetical protein 0.0028 0.0061 0.0093
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0103 0.0157
Onchocerca volvulus 0.0042 0.0212 0.0693
Echinococcus granulosus thioredoxin glutathione reductase 0.0053 0.0339 0.0695
Brugia malayi isocitrate dehydrogenase 0.0025 0.0022 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0143 0.1349 1
Schistosoma mansoni thyroid hormone receptor 0.0311 0.3242 0.6649
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0097 0.0836 0.1715
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0061 0.0061
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0053 0.0339 0.0431
Plasmodium vivax hypothetical protein, conserved 0.0035 0.013 0.1532
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0044 0.0236 0.036
Loa Loa (eye worm) ctsf protein 0.0037 0.0163 0.0248
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0042 0.0212 0.0435
Schistosoma mansoni amine GPCR 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0171 0.1661 0.2532
Onchocerca volvulus 0.0035 0.013 0.0392
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0372 0.0566
Schistosoma mansoni hypothetical protein 0.0028 0.0061 0.0125
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.014 0.1321 0.1321
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.0386 0.2858
Mycobacterium ulcerans DNA polymerase III subunit alpha 0.0239 0.2433 0.309
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0042 0.0212 0.0323
Brugia malayi Cathepsin L-like cysteine proteinase 0.0025 0.0023 0.0036
Brugia malayi AKH receptor 0.0028 0.0061 0.0093
Echinococcus granulosus Niemann Pick C1 protein 0.0124 0.1142 0.2343
Onchocerca volvulus 0.0042 0.0212 0.0693
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0073 0.0562 0.2047
Loa Loa (eye worm) hypothetical protein 0.008 0.0647 0.0986
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0193 0.0703
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0086 0.0711 0.0711
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.0386 0.4531
Schistosoma mansoni nAChR subunit 0.0042 0.0212 0.0435
Brugia malayi Cation transporter family protein 0.0042 0.0212 0.0323
Schistosoma mansoni hypothetical protein 0.0036 0.0147 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0048 0.0174
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0035 0.013 0.0267
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0086 0.0711 0.1458
Loa Loa (eye worm) hypothetical protein 0.0037 0.0163 0.0248
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.006 0.0217
Schistosoma mansoni hypothetical protein 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Schistosoma mansoni transcription factor LCR-F1 0.0081 0.0648 0.1328
Entamoeba histolytica P-glycoprotein-2 0.0043 0.0225 0.3112
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0034 0.0118 0.018
Brugia malayi nuclear receptor NHR-67 0.008 0.0647 0.0986
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0372 0.0566
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0171 0.1661 0.3407
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0193 0.0703
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0043 0.0225 0.0225
Brugia malayi nuclear receptor RXR 0.009 0.0755 0.1151
Giardia lamblia Multidrug resistance-associated protein 1 0.0043 0.0226 0.2193
Loa Loa (eye worm) hypothetical protein 0.0171 0.1661 0.2532
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0043 0.0225 0.0818
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0033 0.0114 0.1579
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0035 0.013 0.013
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.009 0.0755 0.1151
Echinococcus multilocularis multidrug resistance associated protein 4 0.0025 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0023 0.0085
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0121 0.1105 0.1404
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.006 0.0217
Onchocerca volvulus Bile acid receptor homolog 0.0171 0.1661 0.601
Trypanosoma brucei p-glycoprotein 0.0043 0.0226 0.1672
Brugia malayi orphan nuclear receptor NR2E1 0.008 0.0647 0.0986
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0171 0.1661 0.2532
Brugia malayi glutathione reductase 0.0053 0.0339 0.0517
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0386 0.1404
Toxoplasma gondii cathepsin CPL 0.0037 0.0163 0.1915
Echinococcus granulosus multidrug resistance protein 1 0.0043 0.0225 0.046
Echinococcus multilocularis dnaJ subfamily B 0.0456 0.4876 0.4876
Giardia lamblia ABC transporter, putative 0.0043 0.0226 0.2193
Echinococcus multilocularis protein patched 0.0037 0.0162 0.0162
Schistosoma mansoni cpg binding protein 0.0034 0.0122 0.025
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0162 0.0589
Brugia malayi Cathepsin L-like precursor 0.0037 0.0163 0.0248
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0042 0.0212 0.0435
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0061 0.0125
Schistosoma mansoni nuclear hormone receptor 0.008 0.0647 0.1327
Brugia malayi nuclear receptor RXR 0.008 0.0647 0.0986
Onchocerca volvulus Huntingtin homolog 0.0108 0.0961 0.3441
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0042 0.0212 0.0323
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0025 0.0022 0.0045
Schistosoma mansoni ATPase 0.0097 0.0836 0.1715
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0087 0.0722 1
Echinococcus granulosus neuropeptide receptor 0.0028 0.0061 0.0125
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0025 0.0022 0.0022
Brugia malayi MAP kinase sur-1 0.0057 0.0386 0.0588
Loa Loa (eye worm) nuclear receptor NHR-67 0.008 0.0647 0.0986
Entamoeba histolytica P-glycoprotein-2, putative 0.0043 0.0225 0.3112
Leishmania major cysteine peptidase A (CPA) 0.0037 0.0163 0.1208
Echinococcus multilocularis glycine receptor subunit beta 0.0042 0.0212 0.0212
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0073 0.0562 0.2047
Brugia malayi calcium ATPase 0.0028 0.0054 0.0082
Leishmania major pentamidine resistance protein 1 0.0043 0.0226 0.1672
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0171 0.1661 0.2532
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.006 0.0441
Echinococcus granulosus Nuclear hormone receptor HR96 0.008 0.0647 0.1327
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.0386 0.0588
Brugia malayi cathepsin L-like precursor 0.0025 0.0023 0.0036
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0171 0.1661 0.1661
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Brugia malayi G-protein coupled receptor 0.0028 0.0061 0.0093
Brugia malayi ABC transporter transmembrane region family protein 0.0043 0.0226 0.0344
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0099 0.0851 0.0851
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0037 0.0163 0.0593
Loa Loa (eye worm) TYRA-2 protein 0.0028 0.0061 0.0093
Mycobacterium ulcerans proteasome PrcA 0.0722 0.7872 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Brugia malayi multidrug resistance related protein 1 0.0043 0.0226 0.0344
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0043 0.0225 0.0818
Plasmodium vivax ataxin-2 like protein, putative 0.0056 0.0376 0.4422
Echinococcus multilocularis nAChR subunit 0.0042 0.0212 0.0212
Echinococcus granulosus Ankyrin 0.0032 0.0106 0.0218
Brugia malayi Membrane calcium atpase protein 3 0.006 0.0413 0.0629
Echinococcus granulosus serotonin receptor 0.0028 0.0061 0.0125
Echinococcus granulosus multidrug resistance associated protein 4 0.0025 0.0017 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0171 0.1661 0.2532
Onchocerca volvulus 0.0037 0.0163 0.0512
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0086
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0043 0.0225 0.0818
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0032 0.0103 0.0103
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0035 0.013 0.0199
Brugia malayi hypothetical protein 0.0036 0.0151 0.023
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0073 0.0562 0.4166
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0171 0.1661 0.1661
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0042 0.0212 0.0323
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0171 0.1661 0.2532
Schistosoma mansoni nuclear hormone receptor 0.008 0.0647 0.1327
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0042 0.0212 0.0323
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0061 0.0061
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0086 0.0711 0.9851
Entamoeba histolytica ATP-binding cassette protein, putative 0.0043 0.0226 0.3127
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0722 0.7872 1
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0097 0.0836 0.6199
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0386 0.0791
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0043 0.0225 0.0818
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0711 0.2589
Leishmania major cathepsin L-like protease 0.0037 0.0163 0.1208
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0081 0.0294
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.008 0.0647 0.0986
Loa Loa (eye worm) hypothetical protein 0.008 0.0647 0.0986
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0042 0.0212 0.0212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0143 0.1349 1
Schistosoma mansoni nuclear receptor 0.008 0.0647 0.1327
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0042 0.0212 0.0212
Echinococcus granulosus multidrug resistance associated protein 7 0.0043 0.0226 0.0463
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0042 0.0212 0.0435
Schistosoma mansoni alpha-1 adrenergic receptor 0.0028 0.0061 0.0125
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0028 0.0061 0.0125
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.005 0.0309 0.0635
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) 0.024 0.2446 0.3108
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0114 0.1029 1
Trypanosoma brucei P-type H+-ATPase, putative 0.0046 0.0263 0.1952
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.005 0.0299 0.0379
Echinococcus granulosus geminin 0.0268 0.2754 0.5649
Onchocerca volvulus 0.0028 0.0061 0.0139
Loa Loa (eye worm) hypothetical protein 0.0164 0.1591 0.2425
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0042 0.0212 0.0435
Onchocerca volvulus 0.006 0.0421 0.1458
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0171 0.1661 0.2532
Plasmodium vivax glutathione reductase, putative 0.0053 0.0339 0.3986
Brugia malayi hypothetical protein 0.0028 0.0061 0.0093
Brugia malayi G protein-coupled receptor 0.0028 0.0061 0.0093
Loa Loa (eye worm) hypothetical protein 0.0042 0.0218 0.0333
Brugia malayi hypothetical protein 0.017 0.1653 0.2519
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0171 0.1661 0.2532
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0035 0.013 0.0199
Loa Loa (eye worm) hypothetical protein 0.009 0.0755 0.1151
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0376 0.4422
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0043 0.0225 0.0818
Echinococcus multilocularis Niemann Pick C1 protein 0.0124 0.1142 0.1142
Trichomonas vaginalis cation-transporting ATPase, putative 0.0046 0.0263 0.0959
Onchocerca volvulus 0.0028 0.0061 0.0139
Loa Loa (eye worm) hypothetical protein 0.0046 0.0256 0.0391
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0121 0.1105 0.1404
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0025 0.0022 0.0257
Echinococcus multilocularis Ankyrin 0.0032 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Brugia malayi hypothetical protein 0.008 0.0647 0.0986
Echinococcus granulosus Na:K ATPase alpha subunit 0.0114 0.1029 0.211
Schistosoma mansoni neuropeptide receptor 0.0028 0.0061 0.0125
Onchocerca volvulus 0.0042 0.0212 0.0693
Brugia malayi hypothetical protein 0.0365 0.3855 0.5875
Onchocerca volvulus Huntingtin homolog 0.0108 0.0961 0.3441
Loa Loa (eye worm) hypothetical protein 0.0494 0.5299 0.8077
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0171 0.1661 0.2532
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0037 0.0163 0.0593
Toxoplasma gondii isocitrate dehydrogenase 0.0025 0.0022 0.0257
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0104 0.0915 0.1162
Loa Loa (eye worm) hypothetical protein 0.0204 0.2035 0.3102
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0135 0.1258 0.1598
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.006 0.0217
Loa Loa (eye worm) hypothetical protein 0.0048 0.0278 0.0424
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0135 0.1258 0.1598
Onchocerca volvulus Putative nachr subunit 0.0042 0.0212 0.0693
Brugia malayi steroid hormone receptor 0.0171 0.1661 0.2532
Echinococcus multilocularis sterol regulatory element binding protein 0.0037 0.0162 0.0162
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0442 0.4721 0.9683
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0163 0.0593
Brugia malayi CXXC zinc finger family protein 0.0032 0.0101 0.0155
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0051 0.0314 0.2326
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.013 0.1209 0.8966
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0171 0.1661 0.3407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.011 0.04
Loa Loa (eye worm) hypothetical protein 0.0056 0.0376 0.0573
Brugia malayi conserved hypotetical protein 0.008 0.0647 0.0986
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.008 0.0647 0.0647
Echinococcus granulosus tar DNA binding protein 0.0044 0.0236 0.0485
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0061 0.0061
Schistosoma mansoni opsin-like receptor 0.0028 0.0061 0.0125
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.006 0.0421 0.0641
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0042 0.0212 0.0435
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0061 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0171 0.1661 0.2532
Trypanosoma cruzi cysteine peptidase, putative 0.0143 0.1349 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Brugia malayi G-protein coupled receptor 0.0028 0.0061 0.0093
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.0199
Echinococcus multilocularis multidrug resistance associated protein 1 0.0043 0.0226 0.0226
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.0386 0.0386
Schistosoma mansoni retinoid-x-receptor (RXR) 0.009 0.0755 0.1549
Schistosoma mansoni cathepsin F (C01 family) 0.0037 0.0163 0.0334
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0086 0.0711 0.1083
Echinococcus multilocularis protein dispatched 1 0.0043 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.008 0.0647 0.0986
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0171 0.1661 0.3407
Schistosoma mansoni hypothetical protein 0.0036 0.0147 0.03
Echinococcus multilocularis expressed conserved protein 0.0082 0.0662 0.0662
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0171 0.1661 0.3407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0164 0.0596
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0034 0.0126 0.0193
Schistosoma mansoni hypothetical protein 0.0081 0.0648 0.1328
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0234 0.2382 0.363
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0171 0.1661 0.2532
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0043 0.0226 0.1672
Echinococcus granulosus expressed conserved protein 0.0082 0.0662 0.1358
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0043 0.0225 0.0818
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.006 0.0413 0.3059
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.008 0.0647 0.2288
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0061 0.0125
Echinococcus multilocularis multidrug resistance protein 1 0.0043 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Trichomonas vaginalis adenylate cyclase, putative 0.0028 0.006 0.0217
Brugia malayi RE15519p 0.0028 0.0061 0.0093
Loa Loa (eye worm) DR-78 0.008 0.0647 0.0986
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0069 0.0069
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0028 0.0061 0.0093
Loa Loa (eye worm) hypothetical protein 0.0032 0.0106 0.0162
Schistosoma mansoni adenoreceptor 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0171 0.1661 0.1661
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0028 0.006 0.0245
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.005 0.0309 0.2294
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0073 0.0562 0.4166
Loa Loa (eye worm) ACC-1 protein 0.0042 0.0212 0.0323
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Onchocerca volvulus 0.006 0.0421 0.1458
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0043 0.0225 0.0818
Onchocerca volvulus 0.0028 0.0061 0.0139
Brugia malayi Nuclear hormone receptor-like 1 0.009 0.0755 0.1151
Schistosoma mansoni single-minded 0.0109 0.0967 0.1983
Echinococcus granulosus multidrug resistance protein 1 0.0043 0.0225 0.046
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0043 0.0225 0.2639
Brugia malayi hypothetical protein 0.0035 0.013 0.0199
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0042 0.0212 0.0323
Entamoeba histolytica ATP-binding cassette protein, putative 0.0043 0.0226 0.3127
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0035 0.013 0.0536
Trichomonas vaginalis cation-transporting ATPase, putative 0.0097 0.0836 0.3046
Loa Loa (eye worm) hypothetical protein 0.0204 0.2035 0.3102
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0028 0.0061 0.0061
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.008 0.0647 0.0986
Entamoeba histolytica hypothetical protein 0.0081 0.0648 0.8977
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0028 0.0061 0.0125
Brugia malayi Cation transporter family protein 0.0042 0.0212 0.0323
Onchocerca volvulus 0.0028 0.0061 0.0139
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0042 0.0212 0.0323
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0028 0.0061 0.0093
Onchocerca volvulus 0.0081 0.0648 0.2293
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.006 0.0413 0.0846
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0365 0.3855 0.5875
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.005 0.0309 0.2294
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0042 0.0212 0.0323
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0042 0.0212 0.0323
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0143 0.1349 1
Schistosoma mansoni multidrug resistance protein 0.0043 0.0225 0.046
Onchocerca volvulus 0.0037 0.0163 0.0512
Loa Loa (eye worm) nuclear receptor nhr-7B 0.008 0.0647 0.0986
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0043 0.0225 0.0923
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0061 0.0125
Mycobacterium tuberculosis Probable oxidoreductase 0.0135 0.1258 0.1598
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Echinococcus multilocularis ATP binding cassette sub family B 0.0042 0.0217 0.0217
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0043 0.0225 0.0818
Trichomonas vaginalis ABC transporter, putative 0.0043 0.0225 0.0818
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Onchocerca volvulus 0.0171 0.1661 0.601
Onchocerca volvulus 0.0037 0.0163 0.0512
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0061 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0048 0.0174
Treponema pallidum sodium- and chloride- dependent transporter 0.0204 0.2035 0.8366
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0171 0.1661 0.2532
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0126 0.0259
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0073 0.0562 0.4166
Brugia malayi hypothetical protein 0.0028 0.0061 0.0093
Toxoplasma gondii hypothetical protein 0.0035 0.013 0.1532
Loa Loa (eye worm) nuclear hormone receptor 0.008 0.0647 0.0986
Loa Loa (eye worm) hypothetical protein 0.0171 0.1661 0.2532
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0042 0.0212 0.0212
Schistosoma mansoni biogenic amine receptor 0.0028 0.0061 0.0125
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0061 0.0061
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0143 0.1349 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0043 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.008 0.0647 0.0986
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0061 0.0423 0.0645
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.006 0.0413 0.1503
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0086 0.0711 0.5269
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0042 0.0212 0.0435
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0035 0.013 0.0267
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.006 0.0441
Loa Loa (eye worm) MH2 domain-containing protein 0.0189 0.1864 0.2841
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.0199
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0028 0.0061 0.0093
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0035 0.013 0.0199
Loa Loa (eye worm) hypothetical protein 0.017 0.1653 0.2519
Echinococcus granulosus aryl hydrocarbon receptor 0.0028 0.006 0.0122
Echinococcus multilocularis dro:myosuppressin receptor 0.0028 0.0061 0.0061
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0099 0.0851 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0135 0.1258 0.1598
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0043 0.0225 0.0285
Loa Loa (eye worm) multidrug resistance-associated protein 0.0025 0.0024 0.0037
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0028 0.0061 0.0061
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0042 0.0212 0.0212
Schistosoma mansoni zinc finger protein 0.008 0.0647 0.1327
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0025 0.0022 0.0162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0164 0.0596
Trichomonas vaginalis ABC transporter, putative 0.0043 0.0225 0.0818
Brugia malayi ecdysone receptor 0.008 0.0647 0.0986
Entamoeba histolytica P-glycoprotein 5, putative 0.0043 0.0225 0.3112
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0061 0.0061
Echinococcus granulosus neuropeptide FF receptor 2 0.0028 0.0061 0.0125
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.052 0.1065
Entamoeba histolytica ATP-binding cassette protein, putative 0.0043 0.0226 0.3127
Loa Loa (eye worm) solute carrier family 6 member 4 0.0204 0.2035 0.3102
Mycobacterium leprae Possible regulatory protein 0.0028 0.006 0.0076
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0061 0.0125
Loa Loa (eye worm) steroid hormone receptor 0.0171 0.1661 0.2532
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0106 0.0929 0.1417
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0042 0.0212 0.0323
Echinococcus multilocularis neuropeptide receptor A26 0.0028 0.0061 0.0061
Brugia malayi calcium ATPase 0.0032 0.0099 0.0151
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0106 0.0929 0.1417
Loa Loa (eye worm) multidrug resistance protein 3 0.0043 0.0225 0.0342
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0163 0.0512
Echinococcus granulosus g protein coupled receptor 0.0028 0.0061 0.0125
Echinococcus granulosus X box binding protein 1 0.0255 0.2611 0.5354
Onchocerca volvulus 0.0128 0.1178 0.4238
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.005 0.0309 0.2294
Entamoeba histolytica hypothetical protein 0.0081 0.0648 0.8977
Trypanosoma brucei calcium-translocating P-type ATPase 0.0084 0.0687 0.5092
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0043 0.0225 0.0818
Trypanosoma brucei calcium motive p-type ATPase, putative 0.006 0.0413 0.3059
Giardia lamblia MRP-like ABC transporter 0.0043 0.0226 0.2193
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.006 0.0413 0.0846
Echinococcus granulosus cathepsin l cysteine peptidase 0.0037 0.0163 0.0334
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0042 0.0218 0.0332
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0163 0.0593
Echinococcus multilocularis nuclear receptor nhr 48 0.008 0.0647 0.0647
Onchocerca volvulus 0.0028 0.0061 0.0139
Schistosoma mansoni multidrug resistance protein 0.0043 0.0226 0.0463
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0037 0.0163 0.0248
Loa Loa (eye worm) phosphatidylinositol 3 0.005 0.0309 0.0472
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0069 0.0141
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0023 0.0085
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.019 0.1884 0.1884
Schistosoma mansoni cellular tumor antigen P53 0.0056 0.0367 0.0752
Toxoplasma gondii LsmAD domain-containing protein 0.0056 0.0376 0.4422
Echinococcus granulosus multidrug resistance protein 1 0.0025 0.0023 0.0047
Echinococcus granulosus cpg binding protein 0.0034 0.0122 0.025
Echinococcus granulosus sodium and chloride dependent glycine 0.0035 0.013 0.0267
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Entamoeba histolytica hypothetical protein 0.0081 0.0648 0.8977
Echinococcus granulosus neuropeptide receptor 0.0028 0.0061 0.0125
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0032 0.0099 0.0151
Schistosoma mansoni nAChR subunit 0.0042 0.0212 0.0435
Brugia malayi Tachykinin-like peptides receptor 99D 0.0028 0.0061 0.0093
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0171 0.1661 0.3407
Brugia malayi GnHR receptor homolog 0.0028 0.0061 0.0093
Leishmania major P-type ATPase, putative 0.006 0.0413 0.3059
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0086 0.0711 0.2589
Loa Loa (eye worm) hypothetical protein 0.0087 0.0722 0.11
Schistosoma mansoni histamine h1 receptor 0.0028 0.0061 0.0125
Leishmania major cathepsin L-like protease 0.0037 0.0163 0.1208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0143 0.1349 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0171 0.1661 0.3407
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0073 0.0562 0.7788
Trypanosoma cruzi cruzipain precursor, putative 0.0143 0.1349 1
Onchocerca volvulus 0.008 0.0647 0.2288
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0043 0.0226 0.1672
Echinococcus granulosus Protein patched homolog 1 0.0037 0.0162 0.0332
Mycobacterium ulcerans putative regulatory protein 0.0081 0.0648 0.0824
Trypanosoma cruzi cysteine peptidase, putative 0.0143 0.1349 1
Plasmodium falciparum calcium-transporting ATPase 0.0084 0.0687 0.8073
Brugia malayi hypothetical protein 0.009 0.0755 0.1151
Loa Loa (eye worm) intermediate filament protein 0.006 0.0421 0.0641
Echinococcus granulosus retinoic acid receptor rxr beta a 0.028 0.2899 0.5946
Schistosoma mansoni tar DNA-binding protein 0.0044 0.0236 0.0485
Treponema pallidum DNA polymerase III subunit alpha 0.0239 0.2433 1
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0061 0.0125
Echinococcus granulosus glycine receptor subunit alpha 1 0.0042 0.0212 0.0435
Echinococcus multilocularis Nuclear hormone receptor HR96 0.008 0.0647 0.0647
Schistosoma mansoni sodium-dependent amino acid transporter 0.0035 0.013 0.0267
Schistosoma mansoni cathepsin F (C01 family) 0.0025 0.0023 0.0048
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.032 0.0487
Schistosoma mansoni nuclear receptor nhr-48 0.008 0.0647 0.1327
Echinococcus multilocularis tumor protein p63 0.038 0.4016 0.4016
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0061 0.0061
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0061 0.0125
Echinococcus granulosus glycine receptor subunit beta 0.0042 0.0212 0.0435
Brugia malayi larval opioid receptor 0.0028 0.0061 0.0093
Schistosoma mansoni opsin-like receptor 0.0028 0.0061 0.0125
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0061 0.0061
Brugia malayi Isocitrate dehydrogenase 0.0025 0.0022 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.006 0.0217
Leishmania major cathepsin L-like protease 0.0037 0.0163 0.1208
Trichomonas vaginalis guanylate cyclase, putative 0.0028 0.006 0.0217
Schistosoma mansoni amine GPCR 0.0028 0.0061 0.0125
Onchocerca volvulus 0.0028 0.0061 0.0139
Echinococcus multilocularis aryl hydrocarbon receptor 0.0028 0.006 0.006
Entamoeba histolytica ATP-binding cassette protein, putative 0.0043 0.0226 0.3127
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0061 0.0093
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0042 0.0212 0.0323
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0143 0.1349 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0035 0.013 0.0267
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0028 0.0061 0.0093
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0025 0.0022 0.0162
Brugia malayi nuclear hormone receptor family member nhr-6 0.008 0.0647 0.0986
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0163 0.0593
Echinococcus granulosus allatostatin A receptor 0.0028 0.0061 0.0125
Trypanosoma brucei target of rapamycin kinase 3, putative 0.004 0.0194 0.1435
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0165 0.1597 0.1597
Entamoeba histolytica multidrug resistance protein, putative 0.0043 0.0226 0.3127
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0058 0.0398 0.3868
Brugia malayi excitatory GABA receptor EXP-1A 0.0042 0.0212 0.0323
Brugia malayi ORL1-like opioid receptor 0.0028 0.0061 0.0093
Echinococcus granulosus glycine receptor subunit beta 0.0042 0.0212 0.0435
Echinococcus multilocularis thyroid hormone receptor alpha 0.0311 0.3242 0.3242
Entamoeba histolytica cysteine protease, putative 0.0037 0.0163 0.2258
Schistosoma mansoni thyroid hormone receptor 0.0311 0.3242 0.6649
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0061 0.0125
Toxoplasma gondii P-type ATPase PMA1 0.0046 0.0263 0.3095
Schistosoma mansoni hypothetical protein 0.0036 0.0147 0.03
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.032 0.0655
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Loa Loa (eye worm) hypothetical protein 0.008 0.0647 0.0986
Loa Loa (eye worm) TAR-binding protein 0.0044 0.0236 0.036
Loa Loa (eye worm) hypothetical protein 0.0032 0.0099 0.0151
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.032 0.0655
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0035 0.013 0.1532
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0171 0.1661 0.2532
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0193 0.0703
Echinococcus multilocularis cathepsin L cysteine protease 0.0037 0.0163 0.0163
Plasmodium vivax thioredoxin reductase, putative 0.0053 0.0339 0.3986
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0043 0.0226 0.1672
Echinococcus granulosus thyroid hormone receptor alpha 0.008 0.0647 0.1327
Brugia malayi nuclear hormone receptor family member odr-7 0.008 0.0647 0.0986
Echinococcus multilocularis sex peptide receptor 0.0028 0.0061 0.0061
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0073 0.0562 0.4166
Brugia malayi neuropeptide F receptor 0.0028 0.0061 0.0093
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0032 0.0099 0.0737
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0028 0.0061 0.0061
Trichomonas vaginalis set domain proteins, putative 0.0267 0.2746 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0037 0.0163 0.1915
Onchocerca volvulus 0.017 0.1653 0.5978
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0042 0.0212 0.0435
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0043 0.0225 0.0818
Echinococcus multilocularis neuropeptide FF receptor 2 0.0028 0.0061 0.0061
Echinococcus multilocularis X box binding protein 1 0.0255 0.2611 0.2611
Onchocerca volvulus Protein ultraspiracle homolog 0.0171 0.1661 0.601
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0171 0.1661 0.2532
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0061 0.0061
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0086 0.0711 0.1458
Brugia malayi Nuclear hormone receptor E75 0.008 0.0647 0.0986
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.032 0.0487
Toxoplasma gondii thioredoxin reductase 0.0053 0.0339 0.3986
Mycobacterium tuberculosis Probable dehydrogenase 0.0121 0.1105 0.1404
Onchocerca volvulus 0.0028 0.0061 0.0139
Brugia malayi nuclear receptor NHR-88 0.0171 0.1661 0.2532
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.006 0.0413 0.4849
Echinococcus granulosus nuclear factor of activated T cells 5 0.0165 0.1597 0.3275
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0126 0.0126
Trichomonas vaginalis guanylate cyclase, putative 0.0028 0.006 0.0217
Loa Loa (eye worm) hypothetical protein 0.008 0.0647 0.0986
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0024 0.0015 0.0019
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0043 0.0225 0.0818
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0028 0.0061 0.0125
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.0386 0.2858
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.009 0.0755 0.0755
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0164 0.0596
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0077 0.0281
Echinococcus granulosus 7TM GPCR rhodopsin 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0086
Brugia malayi Niemann-Pick C1 protein precursor 0.0087 0.0722 0.11
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0126 0.0126
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0372 0.0566
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0163 0.0248
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.0386 0.2858
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0042 0.0212 0.0212
Echinococcus granulosus alpha 1A adrenergic receptor 0.0028 0.0061 0.0125
Plasmodium vivax calcium-transporting ATPase, putative 0.0099 0.0851 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0043 0.0225 0.0818
Brugia malayi bHLH-PAS transcription factor 0.0081 0.0648 0.0988
Onchocerca volvulus 0.0028 0.006 0.0133
Schistosoma mansoni hypothetical protein 0.0038 0.0172 0.0353
Schistosoma mansoni biogenic amine receptor 0.0028 0.0061 0.0125
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.032 0.0655
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0043 0.0226 0.0344
Schistosoma mansoni hypothetical protein 0.0032 0.0103 0.0212
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0055 0.0357 0.0544
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0309 0.1127
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0129 0.1193 0.2446
Echinococcus granulosus calcium transporting atpase 0.0084 0.0687 0.1409
Onchocerca volvulus 0.0037 0.0163 0.0512
Echinococcus multilocularis g-protein coupled receptor 0.0028 0.0061 0.0061
Echinococcus multilocularis glycine receptor subunit beta 0.0042 0.0212 0.0212
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.005 0.0309 0.4288
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0121 0.1105 0.1404
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0025 0.0022 0.0022
Onchocerca volvulus 0.0042 0.0212 0.0693
Schistosoma mansoni nAChR subunit 0.0042 0.0212 0.0435
Onchocerca volvulus 0.0035 0.013 0.0392
Loa Loa (eye worm) hypothetical protein 0.0078 0.0616 0.0939
Loa Loa (eye worm) hypothetical protein 0.0171 0.1661 0.2532
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0084 0.0687 0.1409
Leishmania major cathepsin L-like protease 0.0037 0.0163 0.1208
Trypanosoma cruzi P-type H+-ATPase, putative 0.0046 0.0263 0.1952
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.006 0.0413 0.0846
Echinococcus multilocularis G protein coupled receptor 139 0.0028 0.0061 0.0061
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) 0.024 0.2446 0.3108
Echinococcus multilocularis multidrug resistance protein 1 0.0043 0.0225 0.0225
Trypanosoma brucei multidrug resistance protein E 0.0043 0.0226 0.1672
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0043 0.0225 0.0818
Schistosoma mansoni hypothetical protein 0.0028 0.0061 0.0125
Echinococcus granulosus multidrug resistance protein 1 0.0025 0.0023 0.0047
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0042 0.0212 0.0323
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0093
Loa Loa (eye worm) hypothetical protein 0.0028 0.006 0.0091
Loa Loa (eye worm) hypothetical protein 0.0059 0.0408 0.0622
Onchocerca volvulus 0.0267 0.2749 1
Brugia malayi nuclear hormone receptor 0.008 0.0647 0.0986
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0042 0.0212 0.0212
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.005 0.0309 0.2294
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0032 0.0103 0.0212
Loa Loa (eye worm) hypothetical protein 0.0204 0.2035 0.3102
Onchocerca volvulus 0.0042 0.0212 0.0693
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0061 0.0423 0.0645
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0043 0.0225 0.0818
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0035 0.013 0.0267
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.0199
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Trypanosoma cruzi multidrug resistance protein E, putative 0.0043 0.0226 0.1672
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0073 0.0562 0.2047
Loa Loa (eye worm) LGC-31 protein 0.0042 0.0212 0.0323
Loa Loa (eye worm) transcription factor SMAD2 0.0189 0.1864 0.2841
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0028 0.0061 0.0125
Leishmania major hypothetical protein, conserved 0.0056 0.0376 0.2789
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0061 0.0125
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Echinococcus granulosus dnaJ subfamily B 0.0456 0.4876 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0028 0.0061 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0193 0.0703
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0086 0.0711 0.0711
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0074 0.0577 0.799
Brugia malayi Melatonin receptor type 1A 0.0028 0.0061 0.0093
Trypanosoma cruzi P-type H+-ATPase, putative 0.0046 0.0263 0.1952
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0309 0.1127
Brugia malayi follicle stimulating hormone receptor 0.0287 0.2971 0.4529
Trypanosoma brucei P-type H+-ATPase, putative 0.0046 0.0263 0.1952
Schistosoma mansoni multidrug resistance protein 0.0043 0.0225 0.046
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.006 0.0413 0.0413
Trichomonas vaginalis abcb9, putative 0.0043 0.0225 0.0818
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0128 0.1178 0.1497
Leishmania major p-glycoprotein 0.0043 0.0225 0.1664
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0025 0.0023 0.0084
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0035 0.013 0.0267
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0143 0.1349 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0163 0.0593
Loa Loa (eye worm) hypothetical protein 0.0042 0.0212 0.0323
Schistosoma mansoni nAChR subunit 0.0042 0.0212 0.0435
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0043 0.0225 0.0225

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.98 uM Displacement of [3H]MK801 from NMDA receptor in rat brain in presence of 100 uM spermine ChEMBL. 17112642
IC50 (binding) = 8.67 uM Displacement of [3H]MK801 from rat brain NMDA receptor ChEMBL. 17112642

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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