Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Cathepsin B precursor | 0.0155 | 0.1035 | 1 |
Echinococcus granulosus | cathepsin b | 0.046 | 0.3566 | 0.7938 |
Brugia malayi | Protein kinase domain containing protein | 0.0082 | 0.0431 | 0.1209 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0038 | 0.0067 | 0.0188 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0037 | 0.0061 | 0.0591 |
Echinococcus multilocularis | cysteine protease | 0.0038 | 0.0067 | 0.0013 |
Onchocerca volvulus | 0.0038 | 0.0067 | 0.0851 | |
Trypanosoma cruzi | cyclin, putative | 0.0044 | 0.0116 | 0.0325 |
Onchocerca volvulus | 0.0037 | 0.0061 | 0.078 | |
Trichomonas vaginalis | neuroendocrine convertase 2 precursor, putative | 0.0031 | 0.0005 | 0.0048 |
Leishmania major | hypothetical protein, conserved | 0.0082 | 0.0431 | 0.3761 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0038 | 0.0067 | 0.0013 |
Loa Loa (eye worm) | cysteine protease | 0.0038 | 0.0067 | 0.0188 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0061 | 0.0172 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0571 | 0.4493 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Brugia malayi | Cathepsin L-like precursor | 0.0038 | 0.0067 | 0.0188 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0155 | 0.1035 | 0.2902 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0061 | 0.0172 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.046 | 0.3566 | 1 |
Schistosoma mansoni | subfamily S8B non-peptidase homologue (S08 family) | 0.0037 | 0.0061 | 0.0061 |
Onchocerca volvulus | 0.0038 | 0.0067 | 0.0851 | |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.046 | 0.3566 | 0.3566 |
Echinococcus multilocularis | cathepsin b | 0.046 | 0.3566 | 0.791 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0044 | 0.0116 | 0.0325 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0431 | 0.1209 |
Brugia malayi | Cathepsin L-like precursor | 0.0038 | 0.0067 | 0.0188 |
Trypanosoma cruzi | cyclin, putative | 0.0044 | 0.0116 | 0.0325 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0037 | 0.0061 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0061 | 0.0172 |
Onchocerca volvulus | 0.0099 | 0.0574 | 0.7289 | |
Echinococcus multilocularis | proprotein convertase subtilisin:kexin type 5 | 0.0096 | 0.0549 | 0.1102 |
Toxoplasma gondii | PAN domain-containing protein | 0.0348 | 0.2641 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0038 | 0.0067 | 0.0188 |
Toxoplasma gondii | kringle domain-containing protein | 0.0082 | 0.0431 | 0.1434 |
Echinococcus multilocularis | cyclin B | 0.0044 | 0.0116 | 0.0123 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0061 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0068 | 0.0191 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0082 | 0.0431 | 0.096 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0061 | 0.0172 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Brugia malayi | Kringle domain containing protein | 0.0082 | 0.0431 | 0.1209 |
Trichomonas vaginalis | cyclins, putative | 0.0044 | 0.0116 | 0.1119 |
Entamoeba histolytica | cyclin, putative | 0.0044 | 0.0116 | 1 |
Echinococcus granulosus | cyclin B | 0.0044 | 0.0116 | 0.0258 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0038 | 0.0067 | 0.0067 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0038 | 0.0067 | 0.5789 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.046 | 0.3566 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Echinococcus granulosus | calpain A | 0.0064 | 0.0283 | 0.063 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Onchocerca volvulus | 0.0037 | 0.0061 | 0.078 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0005 | 0.0048 |
Onchocerca volvulus | 0.0038 | 0.0067 | 0.0851 | |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.026 | 0.0729 |
Brugia malayi | proprotein convertase 2 | 0.0099 | 0.0576 | 0.1616 |
Onchocerca volvulus | 0.0038 | 0.0067 | 0.0851 | |
Echinococcus granulosus | neuroendocrine convertase 2 | 0.0099 | 0.0576 | 0.1283 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Loa Loa (eye worm) | endoprotease bli-4 | 0.0158 | 0.1065 | 0.2985 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.1065 | 0.2985 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0045 | 0.0126 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.3566 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0038 | 0.0067 | 0.0149 |
Brugia malayi | calpain family protein 1 | 0.0061 | 0.026 | 0.0729 |
Onchocerca volvulus | 0.0037 | 0.0061 | 0.078 | |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0037 | 0.0061 | 0.0591 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0061 | 0.0172 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0061 | 0.0172 |
Trichomonas vaginalis | cyclin A, putative | 0.0044 | 0.0116 | 0.1119 |
Schistosoma mansoni | cyclin B | 0.0044 | 0.0116 | 0.0116 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0005 | 0.0048 |
Onchocerca volvulus | 0.0037 | 0.0061 | 0.078 | |
Onchocerca volvulus | 0.0037 | 0.0061 | 0.078 | |
Brugia malayi | neuroendocrine convertase 1 precursor | 0.0099 | 0.0576 | 0.1616 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0038 | 0.0067 | 0.0188 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0037 | 0.0061 | 0.0172 |
Onchocerca volvulus | 0.0037 | 0.0061 | 0.078 | |
Trichomonas vaginalis | cyclins, putative | 0.0044 | 0.0116 | 0.1119 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0005 | 0.0048 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0082 | 0.0431 | 0.1209 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0202 | 0.0567 |
Toxoplasma gondii | cathepsin CPL | 0.0038 | 0.0067 | 0.0022 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0061 | 0.0172 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0082 | 0.0431 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0125 | 0.0788 | 0.0788 |
Echinococcus multilocularis | cathepsin b | 0.046 | 0.3566 | 0.791 |
Onchocerca volvulus | 0.0037 | 0.0061 | 0.078 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0005 | 0.0048 |
Trichomonas vaginalis | cyclins, putative | 0.0044 | 0.0116 | 0.1119 |
Trichomonas vaginalis | proprotein convertase subtilisin/kexin type, putative | 0.0031 | 0.0005 | 0.0048 |
Loa Loa (eye worm) | fibroinase | 0.0038 | 0.0067 | 0.0188 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0037 | 0.0061 | 0.0172 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0044 | 0.0116 | 0.0325 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0155 | 0.1035 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0038 | 0.0067 | 0.0851 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0038 | 0.0067 | 0.0188 |
Echinococcus granulosus | furin | 0.0158 | 0.1065 | 0.237 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0005 | 0.0048 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0044 | 0.0116 | 0.0504 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Onchocerca volvulus | 0.0037 | 0.0061 | 0.078 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0005 | 0.0048 |
Onchocerca volvulus | 0.0125 | 0.0788 | 1 | |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0064 | 0.0283 | 0.0283 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Brugia malayi | Cathepsin L-like precursor | 0.0038 | 0.0067 | 0.0188 |
Brugia malayi | Cathepsin L-like precursor | 0.0038 | 0.0067 | 0.0188 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0061 | 0.026 | 0.0729 |
Toxoplasma gondii | cathepsin B | 0.0155 | 0.1035 | 0.3775 |
Brugia malayi | celfurPC protein | 0.0128 | 0.081 | 0.2273 |
Brugia malayi | endoprotease bli-4 precursor | 0.0158 | 0.1065 | 0.2985 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Trypanosoma cruzi | cyclin 6, putative | 0.0044 | 0.0116 | 0.0325 |
Brugia malayi | Cathepsin L-like precursor | 0.0038 | 0.0067 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0061 | 0.0172 |
Giardia lamblia | Cathepsin B precursor | 0.0155 | 0.1035 | 1 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0045 | 0.0126 | 0.0353 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0037 | 0.0061 | 0.0172 |
Entamoeba histolytica | cysteine protease, putative | 0.0038 | 0.0067 | 0.5789 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0038 | 0.0067 | 0.0188 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0005 | 0.0048 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0082 | 0.0431 | 0.1209 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0067 | 0.0188 |
Echinococcus granulosus | Furin 1 | 0.0037 | 0.0061 | 0.0136 |
Onchocerca volvulus | 0.0082 | 0.0431 | 0.5475 | |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0064 | 0.0283 | 0.063 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0096 | 0.0549 | 0.5307 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0788 | 0.2208 |
Onchocerca volvulus | 0.0038 | 0.0067 | 0.0851 | |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0061 | 0.0172 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0044 | 0.0116 | 0.0325 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0116 | 0.0325 |
Trichomonas vaginalis | cyclin B, putative | 0.0044 | 0.0116 | 0.1119 |
Onchocerca volvulus | Cathepsin L homolog | 0.0038 | 0.0067 | 0.0851 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0038 | 0.0067 | 0.5789 |
Onchocerca volvulus | 0.0038 | 0.0067 | 0.0851 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0038 | 0.0067 | 0.0188 |
Toxoplasma gondii | PAN domain-containing protein | 0.0348 | 0.2641 | 1 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0061 | 0.0172 |
Schistosoma mansoni | subfamily S8B unassigned peptidase (S08 family) | 0.0158 | 0.1065 | 0.1065 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0037 | 0.0061 | 0.0172 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0037 | 0.0061 | 0.0591 |
Trichomonas vaginalis | cyclin B, putative | 0.0044 | 0.0116 | 0.1119 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0096 | 0.0549 | 0.5307 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0061 | 0.026 | 0.026 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0037 | 0.0061 | 0.0591 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0082 | 0.0431 | 0.0835 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0061 | 0.0172 |
Schistosoma mansoni | family A2 unassigned peptidase (A02 family) | 0.0225 | 0.1614 | 0.1614 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0038 | 0.0067 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0061 | 0.0172 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0037 | 0.0061 | 0.0591 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0266 | 0.0746 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0005 | 0.0048 |
Loa Loa (eye worm) | cathepsin B | 0.0155 | 0.1035 | 0.2902 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0038 | 0.0067 | 0.0188 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.046 | 0.3566 | 0.3566 |
Brugia malayi | calpain family protein 1 | 0.0061 | 0.026 | 0.0729 |
Giardia lamblia | High cysteine membrane protein Group 2 | 0.0059 | 0.0239 | 0.2272 |
Giardia lamblia | Cathepsin B precursor | 0.0155 | 0.1035 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0038 | 0.0067 | 0.0013 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0061 | 0.0172 |
Echinococcus granulosus | cathepsin l1 | 0.0038 | 0.0067 | 0.0149 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0571 | 0.4493 | 1 |
Echinococcus multilocularis | 0.0128 | 0.081 | 0.1691 | |
Trichomonas vaginalis | hypothetical protein | 0.0031 | 0.0005 | 0.0048 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0155 | 0.1035 | 0.1035 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0064 | 0.0283 | 0.0283 |
Loa Loa (eye worm) | proprotein convertase 2 | 0.0037 | 0.0061 | 0.0171 |
Echinococcus multilocularis | cysteine protease | 0.0038 | 0.0067 | 0.0013 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.046 | 0.3566 | 0.3566 |
Echinococcus multilocularis | neuroendocrine convertase 2 | 0.0099 | 0.0576 | 0.1163 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.046 | 0.3566 | 0.3566 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0155 | 0.1035 | 1 |
Brugia malayi | Trypsin family protein | 0.0125 | 0.0788 | 0.2208 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0037 | 0.0061 | 0.0591 |
Onchocerca volvulus | 0.0037 | 0.0061 | 0.078 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | ctsf protein | 0.0038 | 0.0067 | 0.0188 |
Trichomonas vaginalis | leucine-rich repeat protein, BspA family | 0.0031 | 0.0005 | 0.0048 |
Onchocerca volvulus | Cathepsin F homolog | 0.0038 | 0.0067 | 0.0851 |
Echinococcus multilocularis | calpain A | 0.0064 | 0.0283 | 0.0501 |
Trichomonas vaginalis | cyclin B, putative | 0.0044 | 0.0116 | 0.1119 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0126 | 0.0353 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0005 | 0.0048 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0431 | 0.0431 |
Trichomonas vaginalis | cyclins, putative | 0.003 | 0 | 0.0004 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Trichomonas vaginalis | cyclins, putative | 0.0044 | 0.0116 | 0.1119 |
Onchocerca volvulus | 0.0038 | 0.0067 | 0.0851 | |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0064 | 0.0283 | 0.0501 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0116 | 0.0325 |
Toxoplasma gondii | subtilisin SUB12 | 0.0044 | 0.0118 | 0.0218 |
Echinococcus granulosus | cathepsin b | 0.046 | 0.3566 | 0.7938 |
Leishmania major | cyclin | 0.0044 | 0.0116 | 0.0504 |
Trichomonas vaginalis | cyclin B, putative | 0.0044 | 0.0116 | 0.1119 |
Brugia malayi | PAN domain containing protein | 0.0037 | 0.0061 | 0.0172 |
Schistosoma mansoni | furin-1 (S08 family) | 0.0069 | 0.0322 | 0.0322 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0038 | 0.0067 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0788 | 0.2208 |
Onchocerca volvulus | 0.0037 | 0.0061 | 0.078 | |
Onchocerca volvulus | 0.0038 | 0.0068 | 0.0864 | |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0061 | 0.0172 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0005 | 0.0048 |
Echinococcus granulosus | proprotein convertase subtilisin:kexin type 5 | 0.0096 | 0.0549 | 0.1223 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0155 | 0.1035 | 1 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0044 | 0.0116 | 0.1076 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Onchocerca volvulus | 0.0044 | 0.0116 | 0.1471 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Onchocerca volvulus | 0.0037 | 0.0061 | 0.078 | |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0082 | 0.0431 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0061 | 0.0172 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0005 | 0.0048 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0044 | 0.0116 | 0.0504 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0038 | 0.0067 | 0.0067 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0038 | 0.0067 | 0.0013 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0038 | 0.0067 | 0.0188 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0125 | 0.0788 | 0.0788 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0038 | 0.0067 | 0.0648 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0038 | 0.0067 | 0.0188 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (ADMET) | = 233.2 uM | Cytotoxicity against Vero cells after 48 hrs | ChEMBL. | 17045364 |
IC50 (functional) | = 47.8 uM | Antiviral activity against Rubella virus strain THERIEN in Vero cells | ChEMBL. | 17045364 |
Inhibition (functional) | = 96.5 % | Inhibition of Rubella virus strain THERIEN in Vero cells after 48 hrs of high multiplicity infection by plaque assay | ChEMBL. | 17045364 |
Ratio CC50/IC50 (functional) | = 4.9 | Selectivity index, Ratio of CC50 for Vero cells to IC50 for Rubella virus strain THERIEN | ChEMBL. | 17045364 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.