Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | eukaryotic translation initiation factor 4e | 0.0034 | 0.0293 | 0.0293 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0091 | 0.1143 | 0.3346 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0177 | 0.0414 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0028 | 0.0194 | 0.0194 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.0239 | 0.3354 | 1 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.0239 | 0.3354 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.004 | 0.0119 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0058 | 0.0645 | 0.1849 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0038 | 0.0348 | 0.0928 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0017 | 0.004 | 0.004 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0177 | 0.0441 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0086 | 0.106 | 0.8756 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0018 | 0.0057 | 0.0051 |
Toxoplasma gondii | Kazal-type serine protease inhibitor domain-containing protein | 0.0019 | 0.0064 | 0.0444 |
Brugia malayi | Cytochrome P450 family protein | 0.0037 | 0.0332 | 0.099 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0064 | 0.074 | 0.074 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0033 | 0.0274 | 0.0707 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0516 | 0.146 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0031 | 0.0031 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0028 | 0.0194 | 0.0194 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0028 | 0.0194 | 0.0194 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.0033 | 0.0274 | 0.0733 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0192 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0177 | 0.0528 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.0033 | 0.0274 | 0.0733 |
Trypanosoma cruzi | MFS transporter, putative | 0.0028 | 0.0195 | 0.0496 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.0033 | 0.0274 | 0.319 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.018 | 0.2467 | 0.2467 |
Treponema pallidum | peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) | 0.0239 | 0.3354 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0028 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0194 | 0.0579 |
Entamoeba histolytica | hypothetical protein | 0.0017 | 0.004 | 0.0028 |
Mycobacterium ulcerans | hypothetical protein | 0.0033 | 0.0274 | 0.0659 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0794 | 0.2298 |
Mycobacterium tuberculosis | Probable reductase | 0.0086 | 0.106 | 0.8756 |
Echinococcus granulosus | FTZ F1 alpha | 0.0028 | 0.0194 | 0.0194 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0064 | 0.074 | 0.074 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0028 | 0.0194 | 0.0579 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0028 | 0.0194 | 0.0194 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0086 | 0.106 | 0.8756 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0274 | 0.0733 |
Schistosoma mansoni | agrin | 0.0019 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | FKBP5 protein | 0.0239 | 0.3354 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0037 | 0.0343 | 0.1022 |
Toxoplasma gondii | protease inhibitor PI2 | 0.0019 | 0.0064 | 0.0444 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.005 | 0.0525 | 0.1488 |
Trypanosoma brucei | macrophage infectivity potentiator, precursor, putative | 0.0033 | 0.0274 | 0.0707 |
Onchocerca volvulus | Putative organic anion transporter | 0.0028 | 0.0195 | 0.5783 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0727 | 0.2074 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0091 | 0.1143 | 0.3329 |
Leishmania major | FKBP-type peptidyl-prolyl cis-trans isomerase, putative | 0.0033 | 0.0274 | 0.0733 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0148 | 0.0352 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0028 | 0.0194 | 0.0194 |
Plasmodium vivax | hypothetical protein, conserved | 0.0059 | 0.0668 | 0.1919 |
Leishmania major | cytochrome p450-like protein | 0.0037 | 0.0332 | 0.0907 |
Leishmania major | fk506-binding protein 1-like protein | 0.0239 | 0.3354 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0177 | 0.0441 |
Echinococcus multilocularis | follistatin | 0.0019 | 0.0064 | 0.0064 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 | 0.0033 | 0.0274 | 0.0817 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0029 | 0.0029 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type , putative | 0.024 | 0.3372 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.0239 | 0.3354 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0195 | 0.0583 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.0329 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0028 | 0.0194 | 0.0579 |
Plasmodium falciparum | thioredoxin reductase | 0.0037 | 0.0343 | 0.0939 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0086 | 0.106 | 0.8756 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0057 | 0.0057 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0029 | 0.0088 |
Schistosoma mansoni | single-minded | 0.0048 | 0.0503 | 0.0503 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0031 | 0.0031 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.018 | 0.2467 | 0.7355 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.0329 | 0.3914 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.0033 | 0.0274 | 0.0733 |
Leishmania major | eukaryotic translation initiation factor eIF-4E, putative | 0.0034 | 0.0293 | 0.079 |
Mycobacterium ulcerans | putative regulatory protein | 0.0036 | 0.0316 | 0.0785 |
Schistosoma mansoni | immunophilin FK506 binding protein FKBP12 | 0.0239 | 0.3354 | 0.3354 |
Brugia malayi | Cytochrome P450 family protein | 0.0018 | 0.0057 | 0.017 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0028 | 0.0194 | 0.0579 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0028 | 0.0195 | 0.0583 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0028 | 0.0194 | 0.0579 |
Brugia malayi | bHLH-PAS transcription factor | 0.0036 | 0.0316 | 0.0941 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0194 | 0.0579 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0239 | 0.0627 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.0239 | 0.3354 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0727 | 0.2074 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 | 0.0033 | 0.0274 | 0.0817 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.2199 | 0.6556 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0073 | 0.0866 | 0.2512 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0091 | 0.1143 | 0.3328 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0029 | 0.0029 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0329 | 0.0899 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0031 | 0.0239 | 0.06 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0091 | 0.1143 | 0.3407 |
Echinococcus multilocularis | organic anion transporting polypeptide 30B | 0.0028 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0195 | 0.0583 |
Trypanosoma cruzi | macrophage infectivity potentiator, precursor, putative | 0.0033 | 0.0274 | 0.0733 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0029 | 0.0029 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.018 | 0.2467 | 0.2467 |
Onchocerca volvulus | 0.0028 | 0.0195 | 0.5783 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0727 | 0.2096 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0091 | 0.1143 | 0.3346 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase, putative | 0.0239 | 0.3354 | 1 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0018 | 0.0057 | 0.0079 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0031 | 0.0091 |
Onchocerca volvulus | 0.0028 | 0.0195 | 0.5783 | |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0028 | 0.0194 | 0.0579 |
Trypanosoma brucei | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.0239 | 0.3354 | 1 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 | 0.0239 | 0.3354 | 1 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0031 | 0.0239 | 0.0239 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0031 | 0.0031 |
Echinococcus multilocularis | fk506 binding protein | 0.0239 | 0.3354 | 0.3354 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0177 | 0.0528 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.024 | 0.3372 | 0.3372 |
Toxoplasma gondii | FATC domain-containing protein | 0.0017 | 0.004 | 0.0122 |
Mycobacterium ulcerans | FK-506 binding protein, peptidyl-prolyl cis-trans isomerase | 0.0239 | 0.3354 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0072 | 0.0865 | 0.2509 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0073 | 0.0866 | 0.2491 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0031 | 0.0031 |
Chlamydia trachomatis | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0274 | 0.5 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.024 | 0.3372 | 0.3372 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0028 | 0.0194 | 0.0579 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0031 | 0.0031 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0195 | 0.0583 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0727 | 0.2074 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.155 | 0.4622 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0195 | 0.0583 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0018 | 0.0057 | 0.0346 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.018 | 0.2467 | 0.7355 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0194 | 0.0579 |
Entamoeba histolytica | eukaryotic translation initiation factor 4E, putative | 0.0034 | 0.0293 | 0.0786 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0037 | 0.0111 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0516 | 0.146 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0031 | 0.0091 |
Brugia malayi | nuclear receptor NHR-88 | 0.0028 | 0.0194 | 0.0579 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0028 | 0.0194 | 0.5737 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0064 | 0.074 | 0.5959 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0064 | 0.074 | 0.9286 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0239 | 0.0627 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0031 | 0.0239 | 0.0627 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0072 | 0.0865 | 0.2509 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0794 | 0.2298 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0727 | 0.2074 |
Echinococcus granulosus | FK506 binding protein 8 38 kDa | 0.0033 | 0.0274 | 0.0274 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-12 | 0.0239 | 0.3354 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0195 | 0.0583 |
Mycobacterium leprae | PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG | 0.0033 | 0.0274 | 0.1896 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0017 | 0.0031 | 0.0091 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0038 | 0.035 | 0.035 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0017 | 0.004 | 0.0028 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.0033 | 0.0274 | 0.319 |
Trichomonas vaginalis | immunophilin, putative | 0.0239 | 0.3354 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0078 | 0.0944 | 0.2748 |
Loa Loa (eye worm) | kazal-type serine protease inhibitor domain-containing protein | 0.0019 | 0.0064 | 0.0192 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0028 | 0.0194 | 0.0579 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.0033 | 0.0274 | 0.0733 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0028 | 0.0194 | 0.0194 |
Brugia malayi | Cytochrome P450 family protein | 0.0057 | 0.0638 | 0.1902 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0031 | 0.0239 | 0.0627 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0064 | 0.074 | 0.2134 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.0329 | 0.0329 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0018 | 0.0057 | 0.0079 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.0595 | 0.1699 |
Schistosoma mansoni | organic anion transporter | 0.0028 | 0.0195 | 0.0195 |
Trypanosoma cruzi | FKBP-type peptidylprolyl cis-trans isomerase, putative | 0.0033 | 0.0274 | 0.0733 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0028 | 0.0194 | 0.0194 |
Brugia malayi | cytochrome P450 | 0.0018 | 0.0057 | 0.017 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0072 | 0.0865 | 0.2509 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0031 | 0.0091 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0031 | 0.0239 | 0.0712 |
Brugia malayi | hypothetical protein | 0.0162 | 0.2199 | 0.6556 |
Trypanosoma cruzi | Eukaryotic translation initiation factor 4E-1 | 0.0034 | 0.0293 | 0.079 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0033 | 0.0274 | 0.0729 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.0587 | 0.1675 |
Brugia malayi | Kazal-type serine protease inhibitor domain containing protein | 0.0019 | 0.0064 | 0.0192 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0239 | 0.0627 |
Echinococcus granulosus | single minded 2 | 0.0036 | 0.0316 | 0.0316 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0239 | 0.0627 |
Loa Loa (eye worm) | hypothetical protein | 0.0206 | 0.2863 | 0.8535 |
Leishmania major | cytochrome p450-like protein | 0.0018 | 0.0057 | 0.0079 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0517 | 0.1464 |
Trypanosoma brucei | trypanothione reductase | 0.0037 | 0.0343 | 0.0914 |
Loa Loa (eye worm) | sodium-independent organic anion transporter | 0.0028 | 0.0195 | 0.0583 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0058 | 0.0172 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0059 | 0.0666 | 0.1911 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type, putative | 0.024 | 0.3372 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0017 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0037 | 0.0332 | 0.099 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0095 | 0.1203 | 1 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0031 | 0.0239 | 0.06 |
Echinococcus granulosus | cathepsin l1 | 0.0017 | 0.0031 | 0.0031 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0031 | 0.0239 | 0.0239 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0031 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0195 | 0.0583 |
Schistosoma mansoni | follistatin | 0.0019 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0028 | 0.0194 | 0.0579 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.0595 | 0.1699 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.0239 | 0.3354 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0037 | 0.0332 | 0.0882 |
Echinococcus multilocularis | Solute carrier organic anion transporter family | 0.0028 | 0.0195 | 0.0195 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0177 | 0.0441 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0038 | 0.035 | 0.035 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0063 | 0.0727 | 0.2096 |
Echinococcus granulosus | agrin | 0.0019 | 0.0064 | 0.0064 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0028 | 0.0194 | 0.0194 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0028 | 0.0194 | 0.0194 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.0207 | 0.288 | 0.288 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0028 | 0.0194 | 0.0579 |
Onchocerca volvulus | 0.0028 | 0.0195 | 0.5783 | |
Toxoplasma gondii | Kazal-type serine protease inhibitor domain-containing protein | 0.0019 | 0.0064 | 0.0444 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0029 | 0.0029 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0028 | 0.0194 | 0.0579 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0727 | 0.2096 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-30 | 0.0033 | 0.0274 | 0.0817 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0517 | 0.1464 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0031 | 0.0091 |
Echinococcus multilocularis | expressed protein | 0.0019 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0195 | 0.0583 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0057 | 0.0638 | 0.1902 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0195 | 0.0583 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0086 | 0.106 | 0.8756 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0037 | 0.0343 | 0.0939 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0177 | 0.1919 |
Schistosoma mansoni | nuclear hormone receptor | 0.0028 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0028 | 0.0194 | 0.0579 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0086 | 0.106 | 0.8756 |
Entamoeba histolytica | Phosphatidylinositol 3- and 4-kinase family | 0.0017 | 0.004 | 0.0028 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.074 | 0.2071 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0028 | 0.0194 | 0.0194 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0029 | 0.0029 |
Plasmodium vivax | peptidyl-prolyl cis-trans isomerase, putative | 0.0033 | 0.0274 | 0.0733 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.018 | 0.2467 | 0.2467 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0091 | 0.1143 | 0.3328 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0073 | 0.0866 | 0.2512 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0028 | 0.0194 | 0.0579 |
Echinococcus granulosus | follistatin | 0.0019 | 0.0064 | 0.0064 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0031 | 0.0239 | 0.0627 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0028 | 0.0194 | 0.0194 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0031 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0028 | 0.0194 | 0.0579 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.074 | 0.074 |
Plasmodium vivax | glutathione reductase, putative | 0.0037 | 0.0343 | 0.0939 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0194 | 0.0579 |
Brugia malayi | Kazal-type serine protease inhibitor domain containing protein | 0.0019 | 0.0064 | 0.0192 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.0329 | 0.0827 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0037 | 0.0332 | 0.0907 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0684 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.018 | 0.2467 | 0.2467 |
Trypanosoma brucei | Eukaryotic translation initiation factor 4E-1 | 0.0034 | 0.0293 | 0.0764 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0061 | 0.0695 | 0.1999 |
Onchocerca volvulus | Putative organic anion transporter | 0.0028 | 0.0195 | 0.5783 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0329 | 0.0329 |
Onchocerca volvulus | 0.0028 | 0.0195 | 0.5783 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0031 | 0.0091 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0037 | 0.0343 | 0.2494 |
Trypanosoma cruzi | Eukaryotic translation initiation factor 4E-1 | 0.0034 | 0.0293 | 0.079 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0028 | 0.0194 | 0.0194 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0036 | 0.0316 | 0.0316 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0037 | 0.0343 | 0.0939 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0028 | 0.0194 | 0.0579 |
Schistosoma mansoni | fkbp-rapamycin associated protein | 0.0017 | 0.004 | 0.004 |
Schistosoma mansoni | organic anion transporter | 0.0028 | 0.0195 | 0.0195 |
Brugia malayi | secreted modular calcium-binding protein 1 | 0.0019 | 0.0064 | 0.0192 |
Leishmania major | cytochrome p450-like protein | 0.0018 | 0.0057 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0316 | 0.0942 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0028 | 0.0194 | 0.0194 |
Plasmodium vivax | 70 kDa peptidylprolyl isomerase, putative | 0.0239 | 0.3354 | 1 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.0033 | 0.0274 | 0.319 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-33 | 0.0033 | 0.0274 | 0.0817 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.0595 | 0.1699 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0517 | 0.1464 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0091 | 0.1143 | 0.1143 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0727 | 0.2074 |
Leishmania major | peptidyl-prolyl cis-trans isomerase, putative | 0.0033 | 0.0274 | 0.0733 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.0727 | 0.2096 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.0727 | 0.2096 |
Echinococcus multilocularis | 0.0033 | 0.0274 | 0.0274 | |
Echinococcus granulosus | organic anion transporting polypeptide 30B | 0.0028 | 0.0195 | 0.0195 |
Plasmodium falciparum | glutathione reductase | 0.0037 | 0.0343 | 0.0939 |
Brugia malayi | prostaglandin transporter | 0.0028 | 0.0195 | 0.0583 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0028 | 0.0194 | 0.0579 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0028 | 0.0194 | 0.0579 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0017 | 0.004 | 0.0119 |
Brugia malayi | PAS domain containing protein | 0.0048 | 0.0503 | 0.1499 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0037 | 0.0332 | 0.099 |
Toxoplasma gondii | peptidyl-prolyl isomerase FKBP12, putative | 0.0033 | 0.0274 | 0.319 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0028 | 0.0194 | 0.0579 |
Giardia lamblia | GTOR | 0.0091 | 0.1143 | 0.282 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.0272 | 0.1878 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0028 | 0.0194 | 0.0579 |
Brugia malayi | translation initiation factor 4E | 0.0034 | 0.0293 | 0.0874 |
Echinococcus granulosus | FK506 binding protein 2 | 0.0033 | 0.0274 | 0.0274 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0031 | 0.0091 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0091 | 0.1143 | 0.1143 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0194 | 0.0579 |
Brugia malayi | Kazal-type serine protease inhibitor domain containing protein | 0.0019 | 0.0064 | 0.0192 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0794 | 0.2298 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0017 | 0.004 | 0.0028 |
Schistosoma mansoni | fk506 binding protein | 0.0033 | 0.0274 | 0.0274 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0028 | 0.0195 | 0.0583 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 | 0.0033 | 0.0274 | 0.0817 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.0727 | 0.2096 |
Brugia malayi | nuclear hormone receptor | 0.0028 | 0.0194 | 0.0579 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0727 | 0.2074 |
Toxoplasma gondii | thioredoxin reductase | 0.0037 | 0.0343 | 0.4087 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0029 | 0.0029 |
Schistosoma mansoni | immunophilin | 0.024 | 0.3372 | 0.3372 |
Schistosoma mansoni | immunophilin | 0.024 | 0.3372 | 0.3372 |
Toxoplasma gondii | Kazal-type serine protease inhibitor domain-containing protein | 0.0019 | 0.0064 | 0.0444 |
Loa Loa (eye worm) | translation initiation factor 4E | 0.0034 | 0.0293 | 0.0874 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0017 | 0.004 | 0.0028 |
Brugia malayi | ecdysteroid receptor | 0.0028 | 0.0194 | 0.0579 |
Toxoplasma gondii | MA3 domain-containing protein | 0.0059 | 0.0668 | 0.8351 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0548 | 0.0548 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0794 | 0.2298 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0029 | 0.0029 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0048 | 0.0503 | 0.0503 |
Echinococcus multilocularis | eukaryotic translation initiation factor 4E | 0.0034 | 0.0293 | 0.0293 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0029 | 0.0029 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0274 | 0.0274 |
Trichomonas vaginalis | eukaryotic translation initiation factor 4E, putative | 0.0034 | 0.0293 | 0.079 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.0329 | 0.0982 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0329 | 0.0899 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0028 | 0.0194 | 0.0579 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0149 | 0.2012 | 0.5998 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0095 | 0.1203 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0086 | 0.106 | 0.8756 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.0239 | 0.3354 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0329 | 0.0329 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0091 | 0.1143 | 0.3346 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0018 | 0.0057 | 0.0079 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0037 | 0.0332 | 0.0835 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.006 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0274 | 0.0817 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0516 | 0.146 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.0329 | 0.0899 |
Brugia malayi | SPARC precursor | 0.0019 | 0.0064 | 0.0192 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0028 | 0.0194 | 0.0194 |
Leishmania major | peptidylprolyl isomerase-like protein | 0.0239 | 0.3354 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0192 |
Entamoeba histolytica | eukaryotic translation initiation factor 4E, putative | 0.0034 | 0.0293 | 0.0786 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0563 | 0.1678 |
Loa Loa (eye worm) | agrin synaptic family protein | 0.0019 | 0.0064 | 0.0192 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type , putative | 0.0033 | 0.0274 | 0.0729 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0028 | 0.0194 | 0.0194 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.0727 | 0.2096 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0727 | 0.2074 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0517 | 0.1464 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.0239 | 0.3354 | 1 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0091 | 0.1143 | 0.3329 |
Echinococcus multilocularis | agrin | 0.0019 | 0.0064 | 0.0064 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0017 | 0.004 | 0.0028 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0274 | 0.0733 |
Loa Loa (eye worm) | cytochrome P450 | 0.0018 | 0.0057 | 0.017 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0028 | 0.0195 | 0.0583 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0017 | 0.004 | 0.0119 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.018 | 0.2467 | 0.2467 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0031 | 0.0239 | 0.0712 |
Trichomonas vaginalis | fk506 binding protein, putative | 0.0033 | 0.0274 | 0.0733 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0028 | 0.0194 | 0.0194 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0095 | 0.1203 | 1 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase, putative | 0.0033 | 0.0274 | 0.0707 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0028 | 0.0194 | 0.0579 |
Brugia malayi | Kazal-type serine protease inhibitor domain containing protein | 0.0019 | 0.0064 | 0.0192 |
Loa Loa (eye worm) | ctsf protein | 0.0017 | 0.0031 | 0.0091 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0043 | 0.0426 | 0.1165 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.155 | 0.4622 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.074 | 0.074 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase, putative | 0.0017 | 0.004 | 0.0028 |
Toxoplasma gondii | eukaryotic initiation factor-4E, putative | 0.0034 | 0.0293 | 0.344 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.0587 | 0.1675 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0017 | 0.0031 | 0.0091 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0031 | 0.0031 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0028 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0029 | 0.0088 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0029 | 0.0088 |
Echinococcus granulosus | serine protein kinase ATM | 0.0017 | 0.004 | 0.004 |
Loa Loa (eye worm) | glutathione reductase | 0.0037 | 0.0343 | 0.1022 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0177 | 0.0441 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0194 | 0.0579 |
Trypanosoma cruzi | FKBP-type peptidylprolyl cis-trans isomerase, putative | 0.0033 | 0.0274 | 0.0733 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0727 | 0.2074 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0794 | 0.2298 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0069 | 0.0206 |
Echinococcus multilocularis | FK506 binding protein 8, 38 kDa | 0.0034 | 0.0291 | 0.0291 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0091 | 0.1143 | 0.3346 |
Echinococcus granulosus | Solute carrier organic anion transporter family | 0.0028 | 0.0195 | 0.0195 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0091 | 0.1143 | 0.3346 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0329 | 0.0899 |
Onchocerca volvulus | 0.0019 | 0.0064 | 0.119 | |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0329 | 0.0874 |
Echinococcus granulosus | programmed cell death protein 4 | 0.0059 | 0.0668 | 0.0668 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0091 | 0.1143 | 0.3346 |
Echinococcus multilocularis | 0.0018 | 0.0057 | 0.0057 | |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0018 | 0.0057 | 0.0057 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0684 | 1 | 1 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0059 | 0.0668 | 0.1919 |
Leishmania major | peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative | 0.0033 | 0.0274 | 0.0733 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.018 | 0.2467 | 0.2467 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0017 | 0.0031 | 0.0031 |
Schistosoma mansoni | immunophilin | 0.0207 | 0.288 | 0.288 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0563 | 0.1678 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0018 | 0.0057 | 0.0079 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 | 0.0239 | 0.3354 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0028 | 0.0194 | 0.5737 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0727 | 0.2074 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0072 | 0.0865 | 0.2509 |
Onchocerca volvulus | 0.0028 | 0.0195 | 0.5783 | |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0028 | 0.0194 | 0.0194 |
Trichomonas vaginalis | eukaryotic translation initiation factor 4E, putative | 0.0034 | 0.0293 | 0.079 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0329 | 0.0899 |
Onchocerca volvulus | 0.0033 | 0.0274 | 0.8543 | |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0028 | 0.0194 | 0.0194 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0794 | 0.2298 |
Onchocerca volvulus | Putative organic anion transporter | 0.0028 | 0.0195 | 0.5783 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0095 | 0.1203 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0028 | 0.0194 | 0.0194 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0239 | 0.0627 |
Brugia malayi | Inositol-1 | 0.0037 | 0.0329 | 0.0982 |
Onchocerca volvulus | 0.0036 | 0.0316 | 1 | |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0329 | 0.0899 |
Brugia malayi | glutathione reductase | 0.0037 | 0.0343 | 0.1022 |
Leishmania major | eukaryotic translation initiation factor-like | 0.0034 | 0.0293 | 0.079 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0177 | 0.0441 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0037 | 0.0332 | 0.099 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0727 | 0.2074 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0029 | 0.0088 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0028 | 0.0194 | 0.0194 |
Echinococcus granulosus | serine:threonine protein kinase SMG1 | 0.0017 | 0.004 | 0.004 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0069 | 0.0117 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.0329 | 0.0895 |
Brugia malayi | hypoxia-induced factor 1 | 0.0149 | 0.2012 | 0.5998 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0028 | 0.0194 | 0.0194 |
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase, putative | 0.0033 | 0.0274 | 0.0733 |
Leishmania major | eukaryotic translation initiation factor-like protein | 0.0034 | 0.0293 | 0.079 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.0207 | 0.288 | 0.288 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0.0272 | 0.1878 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0563 | 0.1678 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0028 | 0.0194 | 0.0194 |
Trichomonas vaginalis | eukaryotic translation initiation factor 4E, putative | 0.0034 | 0.0293 | 0.079 |
Toxoplasma gondii | transporter, major facilitator family protein | 0.0028 | 0.0195 | 0.2159 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0563 | 0.1678 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0028 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0194 | 0.0579 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0028 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | fibroinase | 0.0017 | 0.0031 | 0.0091 |
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase FKBP35 | 0.0239 | 0.3354 | 1 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0091 | 0.1143 | 0.3346 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0028 | 0.0194 | 0.0579 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.155 | 0.4622 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0028 | 0.0194 | 0.0579 |
Mycobacterium tuberculosis | Probable trigger factor (TF) protein Tig | 0.0033 | 0.0274 | 0.1896 |
Giardia lamblia | 70 kDa peptidylprolyl isomerase, putative | 0.0239 | 0.3354 | 1 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.0329 | 0.0329 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0794 | 0.2298 |
Toxoplasma gondii | non-specific serine/threonine protein kinase | 0.0019 | 0.0069 | 0.0507 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0037 | 0.0332 | 0.0907 |
Brugia malayi | steroid hormone receptor | 0.0028 | 0.0194 | 0.0579 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP1A | 0.0239 | 0.3354 | 0.3354 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0031 | 0.0239 | 0.0627 |
Onchocerca volvulus | 0.0033 | 0.0274 | 0.8543 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0316 | 0.0942 |
Schistosoma mansoni | cytochrome P450 | 0.0018 | 0.0057 | 0.0057 |
Echinococcus multilocularis | serine:threonine protein kinase SMG1 | 0.0017 | 0.004 | 0.004 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0195 | 0.0583 |
Schistosoma mansoni | programmed cell death protein | 0.0059 | 0.0668 | 0.0668 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.0727 | 0.2074 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0072 | 0.0865 | 0.2509 |
Leishmania major | trypanothione reductase | 0.0037 | 0.0343 | 0.0939 |
Schistosoma mansoni | programmed cell death protein | 0.0059 | 0.0668 | 0.0668 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0028 | 0.0194 | 0.0579 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0091 | 0.1143 | 0.1143 |
Loa Loa (eye worm) | cysteine protease | 0.0017 | 0.0031 | 0.0091 |
Trichomonas vaginalis | eukaryotic translation initiation factor 4E, putative | 0.0034 | 0.0293 | 0.079 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0028 | 0.0194 | 0.0579 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0031 | 0.0239 | 0.0239 |
Trypanosoma brucei | FKBP-type peptidylprolyl cis-trans isomerase, putative | 0.0033 | 0.0274 | 0.0707 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.0239 | 0.3354 | 1 |
Echinococcus multilocularis | programmed cell death protein 4 | 0.0059 | 0.0668 | 0.0668 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0028 | 0.0194 | 0.0194 |
Toxoplasma gondii | Kazal-type serine protease inhibitor domain-containing protein | 0.0019 | 0.0064 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0192 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0028 | 0.0194 | 0.5737 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.074 | 0.2071 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.018 | 0.2467 | 0.2467 |
Onchocerca volvulus | 0.0028 | 0.0194 | 0.5737 | |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0194 | 0.0579 |
Brugia malayi | Cytochrome P450 family protein | 0.0037 | 0.0332 | 0.099 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0031 | 0.0031 |
Schistosoma mansoni | thyroid hormone receptor | 0.0028 | 0.0194 | 0.0194 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0017 | 0.004 | 0.004 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-13 | 0.0033 | 0.0274 | 0.0817 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0316 | 0.0316 |
Entamoeba histolytica | protein kinase rad3, putative | 0.0017 | 0.004 | 0.0028 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0037 | 0.0343 | 0.1022 |
Echinococcus granulosus | eukaryotic translation initiation factor 4E | 0.0034 | 0.0293 | 0.0293 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0031 | 0.0091 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0068 | 0.0794 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0028 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0091 | 0.1143 | 0.3407 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.074 | 0.2071 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0177 | 0.0441 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 2.88 mg | Antithrombotic activity in Wistar rat assessed as dry thrombus weight at 0.5 umol/kg, iv | ChEMBL. | 17590343 |
Activity (functional) | = 9.06 mg | Antithrombotic activity in Wistar rat assessed as wet thrombus weight at 0.5 umol/kg, iv | ChEMBL. | 17590343 |
IC50 (functional) | = 0.112 umol/L | Inhibition of ADP-induced platelet aggregation in pig platelet rich plasma | ChEMBL. | 17590343 |
IC50 (functional) | = 0.294 umol/L | Inhibition of PAF-induced platelet aggregation in pig platelet rich plasma | ChEMBL. | 17590343 |
log K (ADMET) | = 0.71 | Partition coefficient, log K of the compound | ChEMBL. | 17590343 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.