Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | potassium voltage-gated channel, subfamily H (eag-related), member 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0042 | 0.8236 | 1 |
Entamoeba histolytica | recQ family helicase, putative | 0.002 | 0.2749 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.3929 | 0.4373 |
Echinococcus multilocularis | bloom syndrome protein | 0.002 | 0.2749 | 0.306 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.8985 | 0.8985 |
Schistosoma mansoni | DNA helicase recq1 | 0.002 | 0.2749 | 0.2749 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0013 | 0.1028 | 0.1144 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.3929 | 1 |
Echinococcus granulosus | voltage gated potassium channel | 0.0013 | 0.1028 | 0.1144 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.001 | 0.022 | 0.022 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0.3929 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.3929 | 1 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0045 | 0.8972 | 0.9986 |
Brugia malayi | Bloom's syndrome protein homolog | 0.002 | 0.2749 | 0.306 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0013 | 0.1028 | 0.1144 |
Brugia malayi | hypothetical protein | 0.0024 | 0.3929 | 0.4373 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.002 | 0.2749 | 0.306 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.3929 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0542 | 0.0542 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0045 | 0.8972 | 0.9986 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0013 | 0.1028 | 0.1028 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0045 | 0.8972 | 0.9986 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0049 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.8985 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.3929 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0013 | 0.1028 | 0.1144 |
Echinococcus granulosus | bloom syndrome protein | 0.002 | 0.2749 | 0.306 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.2749 | 0.6819 |
Treponema pallidum | ATP-dependent DNA helicase | 0.001 | 0.0316 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0042 | 0.8236 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.8985 | 1 |
Schistosoma mansoni | DNA helicase recq5 | 0.002 | 0.2749 | 0.2749 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.002 | 0.2749 | 0.306 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.1028 | 0.1144 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.2749 | 0.306 |
Entamoeba histolytica | recQ family DNA helicase | 0.001 | 0.0316 | 0.0381 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0013 | 0.1028 | 0.1144 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.8985 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0.3929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0316 | 0.0352 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.002 | 0.2749 | 0.5 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.2749 | 0.306 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.2749 | 0.6734 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.8985 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.8985 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.2749 | 0.3338 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0542 | 0.0603 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.2749 | 0.3338 |
Brugia malayi | hypothetical protein | 0.0016 | 0.1752 | 0.195 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.002 | 0.2749 | 0.3338 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.3929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.2749 | 0.306 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.8985 | 0.8985 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0045 | 0.8972 | 0.9986 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.3929 | 1 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0542 | 0.0603 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0316 | 0.0352 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.7495 | 0.8342 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.002 | 0.2749 | 0.306 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.8985 | 0.8985 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.2749 | 0.6819 |
Loa Loa (eye worm) | RecQ helicase | 0.002 | 0.2749 | 0.306 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0316 | 0.026 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.001 | 0.0316 | 0.0316 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0013 | 0.1028 | 0.1028 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.002 | 0.2749 | 0.306 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.8985 | 1 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.001 | 0.0316 | 0.026 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.002 | 0.2749 | 0.306 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.