Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | chemokine (C-C motif) receptor 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0151 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0151 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0151 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0151 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0151 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0151 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0151 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0151 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0151 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0151 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0151 | 1 | 1 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0104 | 0.3399 | 0.3399 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0151 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0151 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0151 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0151 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0104 | 0.3399 | 0.3399 |
Brugia malayi | nuclear hormone receptor | 0.0151 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0151 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0151 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0151 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0151 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0151 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0104 | 0.3399 | 0.3399 |
Echinococcus granulosus | serotonin transporter | 0.0104 | 0.3399 | 0.3399 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0151 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0151 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0151 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0151 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.3399 | 0.3399 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0151 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0151 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0151 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0151 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.3399 | 0.3399 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0151 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0151 | 1 | 1 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0104 | 0.3399 | 0.5 |
Loa Loa (eye worm) | serotonin transporter b | 0.0104 | 0.3399 | 0.3399 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0151 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0151 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0151 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0151 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 1 | 1 |
Echinococcus multilocularis | serotonin transporter | 0.0104 | 0.3399 | 0.3399 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.3399 | 0.3399 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0104 | 0.3399 | 0.3399 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0151 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0151 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0151 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0151 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0151 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0151 | 1 | 1 |
Onchocerca volvulus | 0.0151 | 1 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0151 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0151 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0151 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0151 | 1 | 1 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0104 | 0.3399 | 0.3399 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0151 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0151 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0151 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.