Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.0929 | 0.8208 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0622 | 0.488 | 0.5946 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0929 | 0.8208 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0929 | 0.8208 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0478 | 0.3327 | 0.4054 |
Toxoplasma gondii | cathepsin CPL | 0.0929 | 0.8208 | 1 |
Leishmania major | cathepsin L-like protease | 0.0929 | 0.8208 | 1 |
Giardia lamblia | Cathepsin L-like protease | 0.0171 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Plasmodium vivax | vivapain-1 | 0.0478 | 0.3327 | 0.4054 |
Loa Loa (eye worm) | ctsf protein | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0478 | 0.3327 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0622 | 0.488 | 0.5946 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0478 | 0.3327 | 0.4054 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.1094 | 1 | 0.5 |
Giardia lamblia | Cysteine protease | 0.0171 | 0 | 0.5 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0478 | 0.3327 | 0.4054 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0929 | 0.8208 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0622 | 0.488 | 0.5946 |
Entamoeba histolytica | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Giardia lamblia | Cathepsin B precursor | 0.0171 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0622 | 0.488 | 0.5946 |
Giardia lamblia | Cathepsin B precursor | 0.0171 | 0 | 0.5 |
Onchocerca volvulus | 0.0622 | 0.488 | 0.5946 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0929 | 0.8208 | 1 |
Plasmodium vivax | vivapain-2 | 0.0929 | 0.8208 | 1 |
Leishmania major | cathepsin L-like protease | 0.0929 | 0.8208 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0478 | 0.3327 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0929 | 0.8208 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0171 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0929 | 0.8208 | 1 |
Giardia lamblia | Cysteine protease | 0.0171 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0307 | 0.147 | 0.1791 |
Onchocerca volvulus | Cathepsin F homolog | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0622 | 0.488 | 0.5946 |
Loa Loa (eye worm) | hypothetical protein | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Echinococcus granulosus | cathepsin L | 0.0478 | 0.3327 | 0.4054 |
Giardia lamblia | Encystation-specific protease | 0.0171 | 0 | 0.5 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0929 | 0.8208 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0929 | 0.8208 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0171 | 0 | 0.5 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0478 | 0.3327 | 0.4054 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0622 | 0.488 | 0.5946 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0929 | 0.8208 | 1 |
Schistosoma mansoni | cathepsin s | 0.0307 | 0.147 | 0.1791 |
Entamoeba histolytica | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0929 | 0.8208 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0478 | 0.3327 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0929 | 0.8208 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0929 | 0.8208 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0478 | 0.3327 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0307 | 0.147 | 0.1791 |
Giardia lamblia | Cathepsin B precursor | 0.0171 | 0 | 0.5 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0307 | 0.147 | 0.1791 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0929 | 0.8208 | 1 |
Leishmania major | cathepsin L-like protease | 0.0929 | 0.8208 | 1 |
Leishmania major | cathepsin L-like protease | 0.0929 | 0.8208 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0171 | 0 | 0.5 |
Brugia malayi | cathepsin L-like precursor | 0.0622 | 0.488 | 0.5946 |
Loa Loa (eye worm) | hypothetical protein | 0.0307 | 0.147 | 0.1791 |
Echinococcus multilocularis | cysteine protease | 0.0929 | 0.8208 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0171 | 0 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0307 | 0.147 | 0.1791 |
Giardia lamblia | Cathepsin B precursor | 0.0171 | 0 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0929 | 0.8208 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0478 | 0.3327 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0929 | 0.8208 | 1 |
Onchocerca volvulus | 0.0929 | 0.8208 | 1 | |
Loa Loa (eye worm) | cysteine protease | 0.0929 | 0.8208 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0478 | 0.3327 | 0.4054 |
Trypanosoma cruzi | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Giardia lamblia | Hypothetical protein | 0.0171 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0171 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0478 | 0.3327 | 0.4054 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0478 | 0.3327 | 0.4054 |
Onchocerca volvulus | 0.0929 | 0.8208 | 1 | |
Giardia lamblia | Cathepsin L-like protease | 0.0171 | 0 | 0.5 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0171 | 0 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0929 | 0.8208 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0929 | 0.8208 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0478 | 0.3327 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0929 | 0.8208 | 1 |
Plasmodium vivax | unspecified product | 0.0478 | 0.3327 | 0.4054 |
Echinococcus multilocularis | cathepsin L | 0.0478 | 0.3327 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0929 | 0.8208 | 1 |
Plasmodium vivax | unspecified product | 0.0307 | 0.147 | 0.1791 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0478 | 0.3327 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0622 | 0.488 | 0.5946 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Plasmodium vivax | vivapain-3 | 0.0478 | 0.3327 | 0.4054 |
Giardia lamblia | Cysteine protease | 0.0171 | 0 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0929 | 0.8208 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0929 | 0.8208 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0929 | 0.8208 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Onchocerca volvulus | 0.0929 | 0.8208 | 1 | |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0171 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0478 | 0.3327 | 0.4054 |
Echinococcus granulosus | cathepsin l1 | 0.0929 | 0.8208 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0622 | 0.488 | 0.5946 |
Brugia malayi | Cathepsin L-like precursor | 0.0929 | 0.8208 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0929 | 0.8208 | 1 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0171 | 0 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0929 | 0.8208 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0478 | 0.3327 | 0.4054 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.0171 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0929 | 0.8208 | 1 |
Giardia lamblia | Cysteine protease | 0.0171 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Onchocerca volvulus | 0.0929 | 0.8208 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0171 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0478 | 0.3327 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0622 | 0.488 | 0.5946 |
Onchocerca volvulus | 0.0929 | 0.8208 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0929 | 0.8208 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0478 | 0.3327 | 0.4054 |
Giardia lamblia | Cathepsin B precursor | 0.0171 | 0 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0929 | 0.8208 | 1 |
Onchocerca volvulus | 0.0929 | 0.8208 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0929 | 0.8208 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0929 | 0.8208 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0171 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0929 | 0.8208 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0307 | 0.147 | 0.1791 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0929 | 0.8208 | 1 |
Leishmania major | cathepsin L-like protease | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0307 | 0.147 | 0.1791 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0307 | 0.147 | 0.1791 |
Giardia lamblia | Hypothetical protein | 0.0171 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0478 | 0.3327 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Echinococcus granulosus | cysteine protease | 0.0478 | 0.3327 | 0.4054 |
Giardia lamblia | Cathepsin L precursor | 0.0171 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0929 | 0.8208 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0622 | 0.488 | 0.5946 |
Leishmania major | cathepsin L-like protease | 0.0929 | 0.8208 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0622 | 0.488 | 0.5946 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0929 | 0.8208 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0171 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0478 | 0.3327 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0478 | 0.3327 | 0.4054 |
Onchocerca volvulus | 0.0929 | 0.8208 | 1 | |
Plasmodium vivax | vivapain-2 | 0.0929 | 0.8208 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0929 | 0.8208 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0929 | 0.8208 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0307 | 0.147 | 0.1791 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0929 | 0.8208 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0478 | 0.3327 | 0.4054 |
Echinococcus granulosus | cathepsin l1 | 0.0622 | 0.488 | 0.5946 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0929 | 0.8208 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.