Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 2 ug ml-1 | Minimum inhibitory concentration (MIC) to C. albicans after 48 hr | ChEMBL. | 12668003 |
MIC (functional) | = 2 ug ml-1 | Minimum inhibitory concentration (MIC) to C. albicans after 48 hr | ChEMBL. | 12668003 |
MIC (functional) | = 8 ug ml-1 | Minimum inhibitory concentration (MIC) to Candida glabrata after 48 hours | ChEMBL. | 12668003 |
MIC (functional) | > 128 ug ml-1 | Minimum inhibitory concentration (MIC) to C. parapsilosis after 48 hr | ChEMBL. | 12668003 |
MIC (functional) | > 128 ug ml-1 | Minimum inhibitory concentration against Cryptoccocus neoformans after 48 hours | ChEMBL. | 12668003 |
MIC (functional) | > 128 ug ml-1 | Minimum inhibitory concentration (MIC) to Aspergillus fumigatus after 48 hr | ChEMBL. | 12668003 |
MIC (functional) | > 128 ug ml-1 | Minimum inhibitory concentration (MIC) of the compound against Aspergillus flavus after 24 hours | ChEMBL. | 12668003 |
MIC (functional) | > 128 ug ml-1 | Minimum inhibitory concentration against Cryptoccocus neoformans after 48 hours | ChEMBL. | 12668003 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.