Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | serine/threonine protein kinase | 0.024 | 0.6292 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 0.9356 | 0.9356 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0141 | 0.2388 | 0.3795 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0141 | 0.2397 | 0.381 |
Loa Loa (eye worm) | hypothetical protein | 0.0279 | 0.7801 | 0.7801 |
Loa Loa (eye worm) | hypothetical protein | 0.0279 | 0.7801 | 0.7801 |
Brugia malayi | protein kinase C II. | 0.024 | 0.6292 | 1 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0141 | 0.2388 | 0.5 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0086 | 0.0246 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.0279 | 0.7801 | 0.7801 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.018 | 0.3952 | 0.6281 |
Schistosoma mansoni | serine/threonine protein kinase | 0.018 | 0.3952 | 0.5865 |
Echinococcus multilocularis | protein kinase c iota type | 0.0096 | 0.0633 | 0.1006 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.024 | 0.6292 | 1 |
Echinococcus granulosus | protein kinase c epsilon type | 0.024 | 0.6292 | 1 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.018 | 0.3952 | 0.6281 |
Onchocerca volvulus | 0.0279 | 0.7801 | 0.5 | |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0195 | 0.4539 | 0.7214 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.1555 | 0.1555 |
Echinococcus granulosus | protein kinase C gamma type | 0.0141 | 0.2397 | 0.381 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.024 | 0.6292 | 0.6292 |
Schistosoma mansoni | serine/threonine protein kinase | 0.018 | 0.3952 | 0.5865 |
Echinococcus granulosus | protein kinase c iota type | 0.0096 | 0.0633 | 0.1006 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Decrease (functional) | NA 0 % | Decrease in blood glucose in mice compared to vehicle controls. | ChEMBL. | 2329563 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.