Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | G protein-coupled receptor | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | hypothetical protein | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | hypothetical protein | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.5815 | 1 |
Onchocerca volvulus | 0.0026 | 0.5815 | 1 | |
Brugia malayi | GnHR receptor homolog | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.5815 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 1 | 0.5 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0017 | 0.1262 | 0.217 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 1 | 0.5 |
Brugia malayi | hypothetical protein | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | Dopamine receptor | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | hypothetical protein | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 1 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0017 | 0.1262 | 0.217 |
Echinococcus multilocularis | musashi | 0.0026 | 0.5815 | 0.5211 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Onchocerca volvulus | 0.0026 | 0.5815 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | hypothetical protein | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.5815 | 0.5815 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.5815 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Echinococcus granulosus | lamin | 0.0026 | 0.5815 | 0.5211 |
Brugia malayi | Serotonin receptor | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.5815 | 0.5815 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | follicle stimulating hormone receptor | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | AKH receptor | 0.0017 | 0.1262 | 0.1262 |
Schistosoma mansoni | lamin | 0.0026 | 0.5815 | 0.5211 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Schistosoma mansoni | lamin | 0.0026 | 0.5815 | 0.5211 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | hypothetical protein | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.5586 | 0.9606 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | hypothetical protein | 0.0017 | 0.1262 | 0.1262 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 1 | 0.5 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.5815 | 0.5211 |
Brugia malayi | larval opioid receptor | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | RE15519p | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0017 | 0.1262 | 0.1262 |
Echinococcus multilocularis | lamin | 0.0026 | 0.5815 | 0.5211 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | Dopamine receptor protein 1 | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | sulfakinin receptor protein | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | Dopamine receptor protein 2 | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | Melatonin receptor type 1A | 0.0017 | 0.1262 | 0.1262 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.5815 | 0.5211 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | putative neuropeptide receptor | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | hypothetical protein | 0.0017 | 0.1262 | 0.1262 |
Brugia malayi | hypothetical protein | 0.0017 | 0.1262 | 0.1262 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | Serotonin receptor | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Brugia malayi | ORL1-like opioid receptor | 0.0017 | 0.1262 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.5815 | 0.5211 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.5815 | 0.5211 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.1262 | 0.217 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.