TDR Targets

Basic information

Technical information

TDR Targets ID: 431665
Name: 1-[2-[4-[(4-methoxyphenyl)-phenanthren-9-ylme thyl]phenoxy]ethyl]piperidine
MW: 501.658 | Formula: C35H35NO2
H donors: 0 H acceptors: 0 LogP: 8.62 Rotable bonds: 8
Rule of 5 violations (Lipinski): 2
SMILES: COc1ccc(cc1)C(c1cc2ccccc2c2c1cccc2)c1ccc(cc1)OCCN1CCCCC1
InChi: 1S/C35H35NO2/c1-37-29-17-13-26(14-18-29)35(27-15-19-30(20-16-27)38-24-23-36-21-7-2-8-22-36)34-25-28-9-3-4-10-31(28)32-11-5-6-12-33(32)34/h3-6,9-20,25,35H,2,7-8,21-24H2,1H3
InChiKey: DLBLNSNJKLOGKW-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

1-[2-[4-[(4-methoxyphenyl)-(9-phenanthryl)methyl]phenoxy]ethyl]piperidine
1-[2-[4-[(4-methoxyphenyl)-phenanthren-9-yl-methyl]phenoxy]ethyl]piperidine
AIDS-219773
AIDS219773
Piperidine, 1-[2-[4-[(4-methoxyphenyl)-9-phenanthrenylmethyl]phenoxy]ethyl]-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	follicle stimulating hormone receptor	0.0246	0.2711	0.7754
Brugia malayi	Nuclear hormone receptor-like 1	0.0162	0.1635	0.4675
Brugia malayi	Nuclear hormone receptor-like 1	0.0307	0.3497	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0047	0.0148	0.0148
Loa Loa (eye worm)	bone morphogenetic protein 1b	0.0056	0.0264	0.0345
Brugia malayi	tailless protein	0.0145	0.1411	0.4036
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0154	0.1533	0.5
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0307	0.3497	1
Toxoplasma gondii	calcium binding egf domain-containing protein	0.0056	0.0264	1
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0049	0.0184	0.0327
Schistosoma mansoni	single-minded	0.0047	0.0158	0.0012
Brugia malayi	nuclear receptor NHR-67	0.0145	0.1411	0.4036
Echinococcus granulosus	FTZ F1 alpha	0.0307	0.3497	0.4142
Brugia malayi	ecdysteroid receptor	0.0307	0.3497	1
Brugia malayi	nuclear hormone receptor family member nhr-6	0.0145	0.1411	0.4036
Brugia malayi	Calcium binding EGF domain containing protein	0.0056	0.0264	0.0755
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0047	0.0148	0.0148
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0162	0.1635	0.1635
Onchocerca volvulus	Bile acid receptor homolog	0.0307	0.3497	1
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.0145	0.1411	0.4036
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0047	0.0148	0.0176
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0307	0.3497	0.3497
Schistosoma mansoni	microtubule-associated protein tau	0.0691	0.8443	1
Loa Loa (eye worm)	hypothetical protein	0.0307	0.3497	1
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0307	0.3497	0.4037
Brugia malayi	nuclear hormone receptor	0.0307	0.3497	1
Echinococcus multilocularis	ecdysone induced protein 78C	0.0307	0.3497	0.3497
Schistosoma mansoni	RAR-like nuclear receptor	0.0307	0.3497	0.4037
Trypanosoma cruzi	mitogen activated protein kinase 4, putative	0.0049	0.0184	0.0327
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0307	0.3497	0.3497
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0307	0.3497	0.4142
Onchocerca volvulus	Protein ultraspiracle homolog	0.0307	0.3497	1
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1411	0.3772
Trichomonas vaginalis	CMGC family protein kinase	0.0049	0.0184	0.5
Schistosoma mansoni	nuclear hormone receptor	0.0307	0.3497	0.4037
Schistosoma mansoni	nuclear hormone receptor	0.0145	0.1411	0.1523
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1411	0.3772
Brugia malayi	Steroid receptor seven-up type 2	0.0307	0.3497	1
Brugia malayi	hypothetical protein	0.0162	0.1635	0.4675
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1411	0.3772
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0047	0.0148	0.0425
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0145	0.1411	0.1411
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0307	0.3497	0.4142
Echinococcus granulosus	nuclear receptor nhr 48	0.0145	0.1411	0.1672
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0307	0.3497	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0307	0.3497	1
Loa Loa (eye worm)	hypothetical protein	0.0307	0.3497	1
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0264	0.0345
Brugia malayi	ecdysone receptor	0.0145	0.1411	0.4036
Trypanosoma brucei	protein kinase, putative	0.0049	0.0184	0.0327
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.005	0.0194	0.0358
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0307	0.3497	0.3497
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0047	0.0148	0.0176
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0145	0.1411	0.1672
Loa Loa (eye worm)	DR-78	0.0145	0.1411	0.3772
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0145	0.1411	0.1672
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0307	0.3497	0.4142
Loa Loa (eye worm)	hypothetical protein	0.0162	0.1635	0.4439
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0307	0.3497	0.4037
Brugia malayi	nuclear receptor RXR	0.0162	0.1635	0.4675
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0307	0.3497	0.4037
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0307	0.3497	0.4142
Brugia malayi	steroid hormone receptor	0.0307	0.3497	1
Schistosoma mansoni	coup transcription factor	0.0307	0.3497	0.4037
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0307	0.3497	0.3497
Brugia malayi	hypothetical protein	0.0159	0.1593	0.4555
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0307	0.3497	0.4142
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0307	0.3497	1
Mycobacterium ulcerans	hypothetical protein	0.0154	0.1533	1
Trypanosoma cruzi	mitochondrial DNA polymerase beta, putative	0.0292	0.3315	1
Brugia malayi	Nuclear hormone receptor-like 1	0.0162	0.1635	0.4675
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0307	0.3497	1
Brugia malayi	Low-density lipoprotein receptor repeat class B containing protein	0.0056	0.0264	0.0755
Echinococcus granulosus	mitogen activated protein kinase	0.0049	0.0184	0.0218
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0307	0.3497	0.3497
Loa Loa (eye worm)	hypothetical protein	0.0162	0.1635	0.4439
Echinococcus multilocularis	nuclear receptor nhr 48	0.0145	0.1411	0.1411
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.0145	0.1411	0.1672
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0307	0.3497	1
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0162	0.1635	0.1792
Trypanosoma brucei	mitochondrial DNA polymerase beta	0.0292	0.3315	1
Brugia malayi	nuclear receptor NHR-88	0.0145	0.1411	0.4036
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0307	0.3497	1
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1411	0.3772
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0162	0.1635	0.1936
Schistosoma mansoni	subfamily M12A unassigned peptidase (M12 family)	0.0056	0.0264	0.0139
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0307	0.3497	0.3497
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0145	0.1411	0.4036
Echinococcus multilocularis	laminin	0.0056	0.0264	0.0264
Trypanosoma cruzi	mitochondrial DNA polymerase beta, putative	0.0292	0.3315	1
Brugia malayi	hypoxia-induced factor 1	0.0146	0.1435	0.4102
Brugia malayi	conserved hypotetical protein	0.0145	0.1411	0.4036
Brugia malayi	hypothetical protein	0.0145	0.1411	0.4036
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0145	0.1411	0.4036
Loa Loa (eye worm)	nuclear hormone receptor	0.0145	0.1411	0.3772
Schistosoma mansoni	egf-like domain protein	0.0056	0.0264	0.0139
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0307	0.3497	0.4142
Brugia malayi	MAP kinase sur-1	0.0049	0.0184	0.0527
Brugia malayi	Fibulin-1 precursor	0.0056	0.0264	0.0755
Schistosoma mansoni	zinc finger protein	0.0145	0.1411	0.1523
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0049	0.0184	0.0327
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0264	0.0345
Loa Loa (eye worm)	hypothetical protein	0.0159	0.1593	0.4314
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0162	0.1635	0.1792
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1411	0.3772
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0307	0.3497	1
Trichomonas vaginalis	CMGC family protein kinase	0.0049	0.0184	0.5
Brugia malayi	photoreceptor-specific nuclear receptor	0.0307	0.3497	1
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0307	0.3497	1
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0162	0.1635	0.4439
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0307	0.3497	0.4037
Brugia malayi	nuclear hormone receptor family member odr-7	0.0145	0.1411	0.4036
Echinococcus multilocularis	mitogen activated protein kinase 3	0.0049	0.0184	0.0184
Trypanosoma cruzi	mitogen activated protein kinase 2, putative	0.0049	0.0184	0.0327
Echinococcus granulosus	thyroid hormone receptor alpha	0.0145	0.1411	0.1672
Loa Loa (eye worm)	hypothetical protein	0.0307	0.3497	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0307	0.3497	1
Schistosoma mansoni	thyroid hormone receptor	0.0307	0.3497	0.4037
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1411	0.3772
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.0138	0.1331	0.3871
Leishmania major	mitochondrial DNA polymerase beta	0.0292	0.3315	1
Echinococcus granulosus	mitogen activated protein kinase 3	0.0049	0.0184	0.0218
Giardia lamblia	Kinase, CMGC MAPK	0.0049	0.0184	0.5
Schistosoma mansoni	retinoic acid receptor RXR	0.0307	0.3497	0.4037
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0307	0.3497	1
Leishmania major	mitochondrial DNA polymerase beta-PAK, putative	0.0138	0.1331	0.3664
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0307	0.3497	1
Schistosoma mansoni	nuclear hormone receptor	0.0145	0.1411	0.1523
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0264	0.0345
Echinococcus multilocularis	microtubule associated protein 2	0.0691	0.8443	0.8443
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0307	0.3497	1
Onchocerca volvulus	Arrow homolog	0.0056	0.0264	0.0755
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0145	0.1411	0.1672
Echinococcus multilocularis	Tolloid protein 1	0.0056	0.0264	0.0264
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0145	0.1411	0.1411
Loa Loa (eye worm)	hypothetical protein	0.0162	0.1635	0.4439
Brugia malayi	nuclear receptor NHR-88	0.0307	0.3497	1
Loa Loa (eye worm)	hypothetical protein	0.0307	0.3497	1
Loa Loa (eye worm)	multiple epidermal growth factor-like domains 6	0.0056	0.0264	0.0345
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0264	0.0345
Echinococcus multilocularis	fibrillin 1	0.0056	0.0264	0.0264
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0264	0.0345
Schistosoma mansoni	thyroid hormone receptor	0.0307	0.3497	0.4037
Echinococcus multilocularis	mitogen activated protein kinase	0.0049	0.0184	0.0184
Brugia malayi	nuclear hormone receptor	0.0145	0.1411	0.4036
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1411	0.3772
Brugia malayi	nuclear receptor RXR	0.0145	0.1411	0.4036
Brugia malayi	hypothetical protein	0.0145	0.1411	0.4036
Loa Loa (eye worm)	steroid hormone receptor	0.0307	0.3497	1
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0307	0.3497	1
Loa Loa (eye worm)	hypothetical protein	0.0162	0.1635	0.4439
Brugia malayi	hypothetical protein	0.0162	0.1635	0.4675
Brugia malayi	Nuclear hormone receptor E75	0.0145	0.1411	0.4036
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0307	0.3497	1
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0246	0.2711	0.7654
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1411	0.3772
Schistosoma mansoni	aryl hydrocarbon receptor	0.0047	0.0158	0.0012
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0307	0.3497	1
Loa Loa (eye worm)	hypothetical protein	0.0307	0.3497	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0307	0.3497	1
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0307	0.3497	0.4037
Trichomonas vaginalis	CMGC family protein kinase	0.0049	0.0184	0.5
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0307	0.3497	0.4037
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1411	0.3772
Trypanosoma brucei	mitochondrial DNA polymerase beta-PAK	0.0138	0.1331	0.3871
Loa Loa (eye worm)	hypothetical protein	0.0307	0.3497	1
Onchocerca volvulus		0.0307	0.3497	1
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0307	0.3497	1
Brugia malayi	PAS domain containing protein	0.0047	0.0158	0.0453
Echinococcus multilocularis	FTZ F1 alpha	0.0307	0.3497	0.3497
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.0145	0.1411	0.1523
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.0145	0.1411	0.1523
Schistosoma mansoni	nuclear receptor	0.0145	0.1411	0.1523
Echinococcus granulosus	laminin	0.0056	0.0264	0.0313
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1411	0.3772
Brugia malayi	Nuclear hormone receptor E75	0.0145	0.1411	0.4036
Toxoplasma gondii	CMGC kinase, MAPK family (ERK) MAPK-1	0.0049	0.0184	0.2605
Onchocerca volvulus		0.0145	0.1411	0.4036
Loa Loa (eye worm)	hypothetical protein	0.0307	0.3497	1
Echinococcus granulosus	Tolloid protein 1	0.0056	0.0264	0.0313
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.0145	0.1411	0.3772
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0307	0.3497	0.4142
Trypanosoma brucei	mitogen activated protein kinase 4, putative	0.0049	0.0184	0.0327
Loa Loa (eye worm)	hypoxia-induced factor 1	0.0146	0.1435	0.3841
Toxoplasma gondii	calcium binding egf domain-containing protein	0.0056	0.0264	1
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0307	0.3497	0.3497
Loa Loa (eye worm)	hypothetical protein	0.0162	0.1635	0.4439
Echinococcus granulosus	ecdysone induced protein 78C	0.0307	0.3497	0.4142
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0307	0.3497	1
Echinococcus granulosus	microtubule associated protein 2	0.0691	0.8443	1
Loa Loa (eye worm)	CMGC/MAPK/ERK1 protein kinase	0.0049	0.0184	0.0107
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1411	0.3772
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.0145	0.1411	0.1411
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1411	0.3772
Brugia malayi	orphan nuclear receptor NR2E1	0.0145	0.1411	0.4036
Schistosoma mansoni	nuclear receptor	0.0145	0.1411	0.1523
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1411	0.3772
Loa Loa (eye worm)	nuclear receptor NHR-67	0.0145	0.1411	0.3772
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0307	0.3497	1
Trichomonas vaginalis	CMGC family protein kinase	0.0049	0.0184	0.5
Schistosoma mansoni	serine/threonine protein kinase	0.0049	0.0184	0.0043
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0307	0.3497	1
Schistosoma mansoni	nuclear receptor nhr-48	0.0145	0.1411	0.1523
Onchocerca volvulus		0.0145	0.1411	0.4036
Loa Loa (eye worm)	hypothetical protein	0.0307	0.3497	1
Loa Loa (eye worm)	low-density lipoprotein receptor repeat class B containing protein	0.0056	0.0264	0.0345
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0307	0.3497	0.4037
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0145	0.1411	0.1411
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.0145	0.1411	0.1411

Activities

Activity type	Activity value	Assay description	Source	Reference
MIC (functional)	= 6.25 ug ml-1	Antitubercular activity against Mycobacterium tuberculosis H37Rv by MABA assay	ChEMBL.	17112639
MIC (functional)	= 6.25 ug ml-1	Antitubercular activity against Mycobacterium tuberculosis H37Rv by microdilution method	ChEMBL.	17112639
MIC (functional)	= 6.25 ug ml-1	Antitubercular activity against Mycobacterium tuberculosis H37Rv by BACTEC method	ChEMBL.	17112639
MIC (functional)	= 6.25 ug ml-1	Antitubercular activity against Mycobacterium tuberculosis H37Rv by MABA assay	ChEMBL.	17112639
MIC (functional)	= 6.25 ug ml-1	Antitubercular activity against Mycobacterium tuberculosis H37Rv by microdilution method	ChEMBL.	17112639
MIC (functional)	= 6.25 ug ml-1	Antitubercular activity against Mycobacterium tuberculosis H37Rv by BACTEC method	ChEMBL.	17112639
Selectivity index (functional)	= 10	Selectivity index, IC50 for vero cells to MIC for Mycobacterium tuberculosis H37Rv	ChEMBL.	17112639

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL245251
PubChem: 3011967

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 431665