Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | methionyl aminopeptidase 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | acetylcholinesterase | 0.0604 | 1 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0102 | 0.0897 | 0.0897 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0102 | 0.0897 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0604 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0102 | 0.0897 | 0.0897 |
Schistosoma mansoni | gliotactin | 0.0102 | 0.0897 | 0.0897 |
Plasmodium falciparum | methionine aminopeptidase 2 | 0.0053 | 0 | 0.5 |
Entamoeba histolytica | methionine aminopeptidase, putative | 0.0053 | 0 | 0.5 |
Plasmodium vivax | methionine aminopeptidase 2, putative | 0.0053 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0897 | 0.0897 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0102 | 0.0897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0897 | 0.0897 |
Echinococcus granulosus | acetylcholinesterase | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0897 | 0.0897 |
Echinococcus multilocularis | neuroligin | 0.0102 | 0.0897 | 0.0897 |
Echinococcus multilocularis | acetylcholinesterase | 0.0604 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0604 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0604 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0102 | 0.0897 | 0.0897 |
Loa Loa (eye worm) | carboxylesterase | 0.0604 | 1 | 1 |
Trypanosoma brucei | methionine aminopeptidase 2, putative | 0.0053 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0604 | 1 | 1 |
Toxoplasma gondii | methionine aminopeptidase 2, putative | 0.0053 | 0 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0102 | 0.0897 | 0.0897 |
Giardia lamblia | Methionine aminopeptidase | 0.0053 | 0 | 0.5 |
Trypanosoma brucei | metallo-peptidase, Clan MG, Family M24 | 0.0053 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0102 | 0.0897 | 0.0897 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0897 | 0.0897 |
Brugia malayi | Carboxylesterase family protein | 0.0102 | 0.0897 | 0.0897 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0102 | 0.0897 | 0.0897 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0102 | 0.0897 | 0.0897 |
Onchocerca volvulus | 0.0102 | 0.0897 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0102 | 0.0897 | 0.0897 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0102 | 0.0897 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0897 | 0.0897 |
Onchocerca volvulus | 0.0102 | 0.0897 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0897 | 0.0897 |
Onchocerca volvulus | 0.0102 | 0.0897 | 1 | |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0102 | 0.0897 | 0.0897 |
Loa Loa (eye worm) | carboxylesterase | 0.0102 | 0.0897 | 0.0897 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0604 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0102 | 0.0897 | 0.0897 |
Onchocerca volvulus | 0.0102 | 0.0897 | 1 | |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0102 | 0.0897 | 0.0897 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24 | 0.0053 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0102 | 0.0897 | 0.0897 |
Brugia malayi | Carboxylesterase family protein | 0.0102 | 0.0897 | 0.0897 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0102 | 0.0897 | 0.0897 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24 | 0.0053 | 0 | 0.5 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0102 | 0.0897 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0897 | 0.0897 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0102 | 0.0897 | 0.0897 |
Onchocerca volvulus | 0.0102 | 0.0897 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0102 | 0.0897 | 0.0897 |
Leishmania major | methionine aminopeptidase 2, putative | 0.0053 | 0 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0102 | 0.0897 | 0.0897 |
Echinococcus granulosus | neuroligin | 0.0102 | 0.0897 | 0.0897 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0102 | 0.0897 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0102 | 0.0897 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.