Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | methionyl aminopeptidase 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | type A flavoprotein, putative | 0.0236 | 0 | 0.5 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0618 | 1 | 1 |
Trichomonas vaginalis | sulfite reductase, putative | 0.0618 | 1 | 1 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0618 | 1 | 1 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0618 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0618 | 1 | 1 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0618 | 1 | 1 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0618 | 1 | 1 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0236 | 0 | 0.5 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0618 | 1 | 1 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.0618 | 1 | 0.5 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0618 | 1 | 1 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0381 | 0.3805 | 0.3805 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0618 | 1 | 1 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0306 | 0.1841 | 0.5 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0618 | 1 | 1 |
Schistosoma mansoni | NADPH flavin oxidoreductase | 0.0311 | 0.1964 | 0.0151 |
Brugia malayi | FAD binding domain containing protein | 0.0618 | 1 | 1 |
Giardia lamblia | Nitric oxide synthase, inducible | 0.0547 | 0.8159 | 0.5 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.0618 | 1 | 1 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0618 | 1 | 1 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0618 | 1 | 1 |
Treponema pallidum | flavodoxin | 0.0236 | 0 | 0.5 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.0618 | 1 | 1 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0236 | 0 | 0.5 |
Plasmodium vivax | flavodoxin domain containing protein | 0.0547 | 0.8159 | 0.8159 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0236 | 0 | 0.5 |
Chlamydia trachomatis | sulfite reductase | 0.0381 | 0.3805 | 0.5 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.0618 | 1 | 1 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0236 | 0 | 0.5 |
Trypanosoma cruzi | p450 reductase, putative | 0.0618 | 1 | 1 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0618 | 1 | 1 |
Leishmania major | cytochrome P450 reductase, putative | 0.0547 | 0.8159 | 0.8159 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0618 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.0547 | 0.8159 | 0.5 |
Brugia malayi | FAD binding domain containing protein | 0.0381 | 0.3805 | 0.3805 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0381 | 0.3805 | 0.2407 |
Trichomonas vaginalis | NADPH fad oxidoreductase, putative | 0.0547 | 0.8159 | 0.8159 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0306 | 0.1841 | 0.5 |
Leishmania major | p450 reductase, putative | 0.0618 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.