Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0273 | 0.0375 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0228 | 0.7275 | 0.7275 |
Loa Loa (eye worm) | MBCTL1 | 0.0055 | 0.0273 | 0.0375 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.0228 | 0.7275 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.6306 | 0.8667 |
Mycobacterium ulcerans | leucyl aminopeptidase | 0.0107 | 0.2387 | 0.5 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0055 | 0.0273 | 0.0375 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0055 | 0.0273 | 0.0375 |
Mycobacterium tuberculosis | Probable aminopeptidase PepB | 0.0107 | 0.2387 | 0.5 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0055 | 0.0273 | 0.0375 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0166 | 0.4756 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0166 | 0.4756 | 0.6537 |
Leishmania major | cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 | 0.0107 | 0.2387 | 0.5 |
Echinococcus granulosus | leucine aminopeptidase protein | 0.0107 | 0.2387 | 0.3281 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0055 | 0.0273 | 0.0273 |
Schistosoma mansoni | alpha-glucosidase | 0.0142 | 0.382 | 0.382 |
Echinococcus granulosus | sterol O acyltransferase 1 | 0.0226 | 0.7201 | 0.9899 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0055 | 0.0273 | 0.0573 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0055 | 0.0273 | 0.0375 |
Brugia malayi | hypothetical protein | 0.0105 | 0.2281 | 0.4796 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0166 | 0.4756 | 0.6537 |
Trypanosoma cruzi | metallo-peptidase, Clan MF, Family M17, putative | 0.0107 | 0.2387 | 0.5 |
Chlamydia trachomatis | cytosol aminopeptidase | 0.0107 | 0.2387 | 0.5 |
Toxoplasma gondii | leucyl aminopeptidase LAP | 0.0107 | 0.2387 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0142 | 0.382 | 0.382 |
Plasmodium falciparum | M17 leucyl aminopeptidase | 0.0107 | 0.2387 | 0.5 |
Trypanosoma brucei | metallo-peptidase, Clan MF, Family M17 | 0.0107 | 0.2387 | 0.5 |
Schistosoma mansoni | sterol O-acyltransferase 1 | 0.0226 | 0.7201 | 0.7201 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0166 | 0.4756 | 0.6537 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0166 | 0.4756 | 0.6537 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0228 | 0.7275 | 1 |
Onchocerca volvulus | 0.0096 | 0.1921 | 1 | |
Echinococcus multilocularis | sterol O acyltransferase 1 | 0.0226 | 0.7201 | 0.9899 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0191 | 0.579 | 0.7958 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.0228 | 0.7275 | 1 |
Mycobacterium leprae | Probable cytosol aminopeptidase PepB | 0.0107 | 0.2387 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | leucyl aminopeptidase | 0.0107 | 0.2387 | 0.5 |
Trypanosoma cruzi | cytosolic leucyl aminopeptidase, putative | 0.0107 | 0.2387 | 0.5 |
Plasmodium vivax | M17 leucyl aminopeptidase, putative | 0.0107 | 0.2387 | 0.5 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0191 | 0.579 | 0.7958 |
Echinococcus multilocularis | leucine aminopeptidase protein | 0.0107 | 0.2387 | 0.3281 |
Loa Loa (eye worm) | hypothetical protein | 0.0226 | 0.7201 | 0.9899 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.