Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.102 | 0.102 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.0384 | 0.0384 |
Schistosoma mansoni | glutaminase | 0.0264 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0011 | 0.0011 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0229 | 0.0423 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Treponema pallidum | NADH oxidase | 0.0013 | 0.0098 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Onchocerca volvulus | 0.0037 | 0.102 | 0.162 | |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0021 | 0.0384 | 0.0599 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Plasmodium falciparum | glutathione reductase | 0.0039 | 0.1093 | 0.9521 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0229 | 0.0423 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.102 | 0.7757 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0384 | 0.0384 |
Toxoplasma gondii | cathepsin CPL | 0.0017 | 0.0229 | 0.1103 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.102 | 0.102 |
Echinococcus multilocularis | tar DNA binding protein | 0.0129 | 0.4671 | 0.8641 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.102 | 0.102 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.102 | 0.101 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.102 | 0.1056 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0017 | 0.0229 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.102 | 0.102 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.102 | 0.1945 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.0384 | 0.071 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4671 | 0.4671 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0229 | 0.1924 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0229 | 0.0423 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0148 | 0.5405 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0384 | 0.0384 |
Toxoplasma gondii | thioredoxin reductase | 0.0039 | 0.1093 | 0.8375 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.0384 | 0.0384 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.102 | 0.102 |
Mycobacterium ulcerans | glutaminase | 0.0264 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0011 | 0.0011 | 0.0011 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.0384 | 0.0384 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.084 | 0.084 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0058 | 0.1862 | 0.8901 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.2314 | 0.2314 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0229 | 0.0661 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.102 | 0.101 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0017 | 0.0229 | 0.1254 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.102 | 0.0931 |
Onchocerca volvulus | 0.0037 | 0.102 | 0.162 | |
Loa Loa (eye worm) | cysteine protease | 0.0017 | 0.0229 | 0.0229 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0144 | 0.5242 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0384 | 0.0384 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.0384 | 0.071 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.102 | 0.102 |
Brugia malayi | RNA binding protein | 0.0129 | 0.4671 | 0.4671 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.102 | 0.0931 |
Echinococcus granulosus | tar DNA binding protein | 0.0129 | 0.4671 | 0.8911 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0229 | 0.0661 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0011 | 0.0011 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0017 | 0.0229 | 0.0437 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.084 | 0.084 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.102 | 0.102 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0013 | 0.0098 | 0.0087 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.102 | 0.102 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.004 | 0.1143 | 1 |
Leishmania major | trypanothione reductase | 0.0039 | 0.1093 | 0.502 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0229 | 0.1103 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0229 | 0.0661 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0234 | 0.8831 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0384 | 0.0732 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0098 | 0.3432 | 0.3818 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.102 | 0.465 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0021 | 0.0384 | 0.071 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0257 | 0.9731 | 0.9731 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0169 | 0.6237 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0384 | 0.0384 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.084 | 0.1554 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0257 | 0.9731 | 0.9731 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0148 | 0.5405 | 0.5405 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0384 | 0.0384 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.084 | 0.084 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0039 | 0.1093 | 0.8375 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.1286 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0011 | 0.0011 | 0.0011 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.102 | 0.1056 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0229 | 0.035 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.0384 | 0.0384 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0229 | 0.0423 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.102 | 0.465 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4671 | 0.4671 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | TAR-binding protein | 0.0129 | 0.4671 | 0.4671 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Plasmodium vivax | glutathione reductase, putative | 0.0039 | 0.1093 | 0.8375 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0229 | 0.0229 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.084 | 0.084 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.0384 | 0.0384 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.2314 | 0.2314 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0013 | 0.0098 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0064 | 0.208 | 1 |
Brugia malayi | beta-lactamase | 0.0037 | 0.102 | 0.102 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4671 | 0.4671 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.102 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0011 | 0.0011 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0013 | 0.0098 | 0.5 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0098 | 0.3432 | 0.3818 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0229 | 0.1103 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.1286 | 0.1276 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0384 | 0.071 |
Loa Loa (eye worm) | glutaminase | 0.0264 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0384 | 0.0384 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.1286 | 0.2454 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0229 | 0.0229 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.208 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.4377 | 0.4377 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0017 | 0.0229 | 0.0661 |
Brugia malayi | Thioredoxin reductase | 0.0039 | 0.1093 | 0.1093 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0384 | 0.0732 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0088 | 0.3044 | 0.3374 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0257 | 0.9731 | 0.9731 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0384 | 0.0384 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0229 | 0.035 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.005 | 0.1543 | 0.729 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.084 | 0.1603 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0384 | 0.071 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0098 | 0.3432 | 0.3818 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0384 | 0.0732 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0102 | 0.3584 | 0.3584 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.102 | 0.101 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0229 | 0.0229 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.084 | 0.1603 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0148 | 0.5405 | 0.5405 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0384 | 0.0384 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.084 | 0.084 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0229 | 0.0229 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.004 | 0.1143 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0017 | 0.0229 | 0.0229 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.102 | 0.1056 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.102 | 0.465 |
Brugia malayi | glutathione reductase | 0.0039 | 0.1093 | 0.1093 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0178 | 0.6596 | 0.6592 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0384 | 0.0384 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.0011 | 0.0011 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0229 | 0.0229 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.084 | 0.084 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.102 | 0.1056 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0102 | 0.3584 | 0.3584 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0088 | 0.3044 | 0.3374 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0257 | 0.9731 | 0.9731 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.102 | 0.0931 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4671 | 0.4671 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.102 | 0.101 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0102 | 0.3584 | 0.3584 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.102 | 0.102 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0011 | 0.0011 | 0.0011 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0013 | 0.0098 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0129 | 0.4671 | 0.4671 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.084 | 0.1554 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0013 | 0.0098 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0384 | 0.0384 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.102 | 0.1886 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.102 | 0.465 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.2314 | 0.2314 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.0384 | 0.0732 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0384 | 0.071 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0013 | 0.0098 | 0.0098 |
Onchocerca volvulus | 0.0037 | 0.102 | 0.162 | |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.102 | 0.102 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0384 | 0.0384 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0017 | 0.0229 | 0.1254 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.1286 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0384 | 0.0732 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0039 | 0.1093 | 0.502 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0088 | 0.3044 | 0.3374 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0039 | 0.1093 | 0.114 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0017 | 0.0229 | 0.035 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.084 | 0.1554 |
Loa Loa (eye worm) | RNA binding protein | 0.0129 | 0.4671 | 0.4671 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0229 | 0.0229 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0178 | 0.6596 | 0.6592 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0229 | 0.0229 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0088 | 0.3044 | 0.3374 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0229 | 0.0661 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.102 | 0.1056 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.102 | 0.102 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0384 | 0.071 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0129 | 0.4671 | 0.4671 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0257 | 0.9731 | 0.9731 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.084 | 0.1603 |
Trichomonas vaginalis | glutaminase, putative | 0.0264 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0017 | 0.0229 | 0.0229 |
Onchocerca volvulus | 0.0021 | 0.0384 | 0.0599 | |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | TAR-binding protein | 0.0129 | 0.4671 | 0.4671 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0229 | 0.0423 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0229 | 0.1924 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0017 | 0.0229 | 0.0437 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.084 | 0.084 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.102 | 0.1056 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0088 | 0.3044 | 0.3374 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.0384 | 0.0384 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.1286 | 1 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Loa Loa (eye worm) | acetyltransferase | 0.0148 | 0.5405 | 0.5405 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0013 | 0.0098 | 0.0087 |
Plasmodium falciparum | thioredoxin reductase | 0.0039 | 0.1093 | 0.9521 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0384 | 0.0384 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0088 | 0.3044 | 0.8393 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0098 | 0.3432 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.208 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0229 | 0.0229 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.102 | 0.101 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0229 | 0.0423 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.102 | 0.102 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.1286 | 0.1276 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0229 | 0.0229 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0039 | 0.1113 | 0.2124 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.0384 | 0.0384 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.102 | 0.0931 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0039 | 0.1093 | 0.1093 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.0384 | 0.0384 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0013 | 0.0098 | 0.0098 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.102 | 0.1056 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0229 | 0.0229 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0021 | 0.0384 | 0.0599 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.102 | 0.1056 |
Echinococcus granulosus | cathepsin l1 | 0.0011 | 0.0011 | 0.0021 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.084 | 0.084 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.102 | 0.1056 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0257 | 0.9731 | 0.9731 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0039 | 0.1113 | 0.206 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0229 | 0.0661 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.0384 | 0.0732 |
Echinococcus granulosus | cathepsin l1 | 0.0017 | 0.0229 | 0.0437 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0229 | 0.1924 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.4377 | 0.4377 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0257 | 0.9731 | 0.9731 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0384 | 0.071 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.4377 | 0.4377 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.208 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0039 | 0.1093 | 0.502 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | fibroinase | 0.0017 | 0.0229 | 0.0229 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0013 | 0.0098 | 0.0187 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.208 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4671 | 0.4671 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0017 | 0.0229 | 0.1254 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Loa Loa (eye worm) | glutathione reductase | 0.0039 | 0.1093 | 0.1093 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.102 | 0.101 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.102 | 0.102 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0257 | 0.9731 | 0.9731 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0384 | 0.0732 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.0011 | 0.0011 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.102 | 0.1056 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.0384 | 0.071 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0384 | 0.0384 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.208 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0017 | 0.0229 | 0.0661 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.0384 | 0.0732 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.102 | 0.7757 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0021 | 0.0384 | 0.0599 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.208 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.3584 | 0.3584 |
Loa Loa (eye worm) | glutaminase 2 | 0.0264 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.0384 | 0.0384 |
Mycobacterium tuberculosis | Probable reductase | 0.0088 | 0.3044 | 0.3374 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.004 | 0.1143 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.0384 | 0.0732 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Inhibition of [3H]GlySar uptake at human PepT1 in Caco2 cells | ChEMBL. | 17887660 | |
Activity (binding) | 0 | Inhibition of [3H]GlySar uptake at human PepT1 in Caco2 cells | ChEMBL. | 17887660 |
Papp (ADMET) | = 5.5 10^-8cm/s | Apparent permeability from apical to basolateral side of human Caco2 cells in presence of 5 mM GlySar | ChEMBL. | 17887660 |
Papp (ADMET) | = 5.5 10^-8cm/s | Apparent permeability from apical to basolateral side of human Caco2 cells in presence of 5 mM GlySar | ChEMBL. | 17887660 |
Papp (ADMET) | = 8.4 10^-8cm/s | Apparent permeability from basolateral to apical side of human Caco2 cells | ChEMBL. | 17887660 |
Papp (ADMET) | = 8.4 10^-8cm/s | Apparent permeability from basolateral to apical side of human Caco2 cells | ChEMBL. | 17887660 |
Papp (ADMET) | = 9.5 10^-8cm/s | Apparent permeability from apical to basolateral side of human Caco2 cells | ChEMBL. | 17887660 |
Papp (ADMET) | = 9.5 10^-8cm/s | Apparent permeability from apical to basolateral side of human Caco2 cells | ChEMBL. | 17887660 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.