Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0098 | 0.3432 | 0.3818 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.102 | 0.101 |
Loa Loa (eye worm) | RNA binding protein | 0.0129 | 0.4671 | 0.4671 |
Trichomonas vaginalis | glutaminase, putative | 0.0264 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0011 | 0.0011 | 0.0011 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0257 | 0.9731 | 0.9731 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0234 | 0.8831 | 1 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0229 | 0.1103 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.102 | 0.0931 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0178 | 0.6596 | 0.6592 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.1286 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0017 | 0.0229 | 0.0229 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0257 | 0.9731 | 0.9731 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0148 | 0.5405 | 0.5405 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.1286 | 1 |
Mycobacterium ulcerans | glutaminase | 0.0264 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0102 | 0.3584 | 0.3584 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.208 | 1 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.1286 | 0.2454 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0144 | 0.5242 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.102 | 0.102 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0011 | 0.0011 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4671 | 0.4671 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Leishmania major | cysteine peptidase A (CPA) | 0.0017 | 0.0229 | 0.0661 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0384 | 0.0384 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0229 | 0.035 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0257 | 0.9731 | 0.9731 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.084 | 0.084 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.084 | 0.1554 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0129 | 0.4671 | 0.4671 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0229 | 0.0661 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.0011 | 0.0011 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.102 | 0.1886 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0384 | 0.0384 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.102 | 0.102 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.0384 | 0.0384 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0257 | 0.9731 | 0.9731 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0229 | 0.035 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0011 | 0.0011 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0257 | 0.9731 | 0.9731 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.004 | 0.1143 | 1 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0257 | 0.9731 | 0.9731 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0017 | 0.0229 | 0.0437 |
Loa Loa (eye worm) | cysteine protease | 0.0017 | 0.0229 | 0.0229 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.102 | 0.102 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0039 | 0.1093 | 0.1093 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0064 | 0.208 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0384 | 0.071 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0129 | 0.4671 | 0.4671 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0229 | 0.0661 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0013 | 0.0098 | 0.0187 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0229 | 0.0423 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4671 | 0.4671 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.102 | 0.465 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.084 | 0.084 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0021 | 0.0384 | 0.071 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0229 | 0.0423 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.102 | 0.102 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.102 | 0.1056 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.0384 | 0.0732 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0039 | 0.1093 | 0.1093 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.005 | 0.1543 | 0.729 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.208 | 1 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0229 | 0.1103 |
Loa Loa (eye worm) | glutaminase 2 | 0.0264 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0021 | 0.0384 | 0.0599 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.102 | 0.101 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.4377 | 0.4377 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0013 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.0384 | 0.071 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.208 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.4377 | 0.4377 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0039 | 0.1093 | 0.502 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.102 | 0.101 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0013 | 0.0098 | 0.0087 |
Loa Loa (eye worm) | TAR-binding protein | 0.0129 | 0.4671 | 0.4671 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.084 | 0.1554 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.102 | 0.465 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0229 | 0.0423 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0013 | 0.0098 | 0.0087 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.102 | 0.465 |
Echinococcus multilocularis | tar DNA binding protein | 0.0129 | 0.4671 | 0.8641 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0229 | 0.0661 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.0011 | 0.0011 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.102 | 0.0931 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.084 | 0.084 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4671 | 0.4671 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.102 | 0.1056 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0384 | 0.0732 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0229 | 0.0229 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0229 | 0.0229 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0088 | 0.3044 | 0.3374 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0257 | 0.9731 | 0.9731 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.102 | 0.102 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0229 | 0.0423 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0011 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Plasmodium falciparum | glutathione reductase | 0.0039 | 0.1093 | 0.9521 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0229 | 0.0229 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.102 | 0.1056 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.102 | 0.7757 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.0384 | 0.0384 |
Toxoplasma gondii | cathepsin CPL | 0.0017 | 0.0229 | 0.1103 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.3584 | 0.3584 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.102 | 0.7757 |
Loa Loa (eye worm) | fibroinase | 0.0017 | 0.0229 | 0.0229 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.1286 | 0.1276 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0229 | 0.1924 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.084 | 0.084 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0229 | 0.0423 |
Echinococcus granulosus | cathepsin l1 | 0.0017 | 0.0229 | 0.0437 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0229 | 0.1924 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0058 | 0.1862 | 0.8901 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.084 | 0.084 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0039 | 0.1113 | 0.206 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.1286 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.102 | 0.102 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0229 | 0.0229 |
Brugia malayi | glutathione reductase | 0.0039 | 0.1093 | 0.1093 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0039 | 0.1113 | 0.2124 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0013 | 0.0098 | 0.5 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0098 | 0.3432 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.084 | 0.084 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4671 | 0.4671 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0017 | 0.0229 | 0.1254 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0229 | 0.0229 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0229 | 0.0229 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0088 | 0.3044 | 0.3374 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.102 | 0.101 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.102 | 0.0931 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0384 | 0.0384 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Onchocerca volvulus | 0.0037 | 0.102 | 0.162 | |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0088 | 0.3044 | 0.3374 |
Brugia malayi | RNA binding protein | 0.0129 | 0.4671 | 0.4671 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.102 | 0.1056 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0384 | 0.0384 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0088 | 0.3044 | 0.8393 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0384 | 0.0384 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.208 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0148 | 0.5405 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.084 | 0.1603 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0384 | 0.071 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.0384 | 0.0384 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.084 | 0.1554 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.0384 | 0.0384 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.102 | 0.102 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.004 | 0.1143 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.102 | 0.1056 |
Onchocerca volvulus | 0.0021 | 0.0384 | 0.0599 | |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.084 | 0.084 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0102 | 0.3584 | 0.3584 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0229 | 0.0229 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.102 | 0.102 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.102 | 0.101 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0384 | 0.0384 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0229 | 0.0661 |
Toxoplasma gondii | thioredoxin reductase | 0.0039 | 0.1093 | 0.8375 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0257 | 0.9731 | 0.9731 |
Loa Loa (eye worm) | glutaminase | 0.0264 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.084 | 0.1603 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.0384 | 0.0384 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0013 | 0.0098 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.2314 | 0.2314 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0384 | 0.0384 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0229 | 0.1924 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.102 | 0.1056 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0017 | 0.0229 | 0.0661 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.102 | 0.465 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.102 | 0.102 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.2314 | 0.2314 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0169 | 0.6237 | 0.6233 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0229 | 0.0661 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.102 | 0.0931 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.102 | 0.0931 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0017 | 0.0229 | 0.0229 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.0384 | 0.0384 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0384 | 0.071 |
Brugia malayi | cathepsin L-like precursor | 0.0011 | 0.0011 | 0.0011 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.084 | 0.084 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0011 | 0.0011 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.0384 | 0.0732 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.0384 | 0.0732 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0021 | 0.0384 | 0.0599 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0229 | 0.0229 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0013 | 0.0098 | 0.0098 |
Echinococcus granulosus | cathepsin l1 | 0.0011 | 0.0011 | 0.0021 |
Leishmania major | trypanothione reductase | 0.0039 | 0.1093 | 0.502 |
Plasmodium falciparum | thioredoxin reductase | 0.0039 | 0.1093 | 0.9521 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.2314 | 0.2314 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.0384 | 0.0384 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0229 | 0.0229 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0017 | 0.0229 | 0.0437 |
Treponema pallidum | NADH oxidase | 0.0013 | 0.0098 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.102 | 0.1056 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0148 | 0.5405 | 0.5405 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.4377 | 0.4377 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0039 | 0.1093 | 0.8375 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.0384 | 0.071 |
Brugia malayi | Thioredoxin reductase | 0.0039 | 0.1093 | 0.1093 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0384 | 0.0732 |
Loa Loa (eye worm) | acetyltransferase | 0.0148 | 0.5405 | 0.5405 |
Mycobacterium tuberculosis | Probable reductase | 0.0088 | 0.3044 | 0.3374 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0098 | 0.3432 | 0.3818 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.102 | 0.102 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.1286 | 0.1276 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.102 | 0.102 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.102 | 0.101 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0088 | 0.3044 | 0.3374 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0178 | 0.6596 | 0.6592 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0229 | 0.0229 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0229 | 0.0423 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0384 | 0.0732 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0384 | 0.071 |
Brugia malayi | beta-lactamase | 0.0037 | 0.102 | 0.102 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0384 | 0.0732 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4671 | 0.4671 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.0384 | 0.0384 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0098 | 0.3432 | 0.3818 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0017 | 0.0229 | 0.0229 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.102 | 0.1056 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0169 | 0.6237 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.0384 | 0.071 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.0384 | 0.0732 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.0384 | 0.0384 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.084 | 0.1603 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.102 | 0.102 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.0384 | 0.0384 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0013 | 0.0098 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0384 | 0.0384 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.004 | 0.1143 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.102 | 0.102 |
Brugia malayi | TAR-binding protein | 0.0129 | 0.4671 | 0.4671 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0017 | 0.0229 | 0.1254 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0017 | 0.0229 | 0.1254 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0088 | 0.3044 | 0.3374 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0384 | 0.0732 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0229 | 0.0218 |
Trypanosoma brucei | trypanothione reductase | 0.0039 | 0.1093 | 0.502 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0384 | 0.0384 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.208 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0102 | 0.3584 | 0.3584 |
Onchocerca volvulus | 0.0017 | 0.0229 | 0.035 | |
Onchocerca volvulus | 0.0037 | 0.102 | 0.162 | |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.102 | 0.1056 |
Echinococcus granulosus | tar DNA binding protein | 0.0129 | 0.4671 | 0.8911 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.208 | 1 |
Onchocerca volvulus | 0.0037 | 0.102 | 0.162 | |
Onchocerca volvulus | Bile acid receptor homolog | 0.0021 | 0.0384 | 0.0599 |
Schistosoma mansoni | glutaminase | 0.0264 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0384 | 0.071 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.102 | 0.1056 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0039 | 0.1093 | 0.114 |
Onchocerca volvulus | Cathepsin F homolog | 0.0017 | 0.0229 | 0.035 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.102 | 0.1945 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0013 | 0.0098 | 0.0181 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0384 | 0.0384 |
Plasmodium vivax | glutathione reductase, putative | 0.0039 | 0.1093 | 0.8375 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0384 | 0.0384 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Inhibition of [3H]GlySar uptake at human PepT1 in Caco2 cells | ChEMBL. | 17887660 | |
Activity (binding) | 0 | Inhibition of [3H]GlySar uptake at human PepT1 in Caco2 cells | ChEMBL. | 17887660 |
Papp (ADMET) | = 12.9 10^-8cm/s | Apparent permeability from basolateral to apical side of human Caco2 cells | ChEMBL. | 17887660 |
Papp (ADMET) | = 12.9 10^-8cm/s | Apparent permeability from basolateral to apical side of human Caco2 cells | ChEMBL. | 17887660 |
Papp (ADMET) | = 29.1 10^-8cm/s | Apparent permeability from apical to basolateral side of human Caco2 cells in presence of 5 mM GlySar | ChEMBL. | 17887660 |
Papp (ADMET) | = 29.1 10^-8cm/s | Apparent permeability from apical to basolateral side of human Caco2 cells in presence of 5 mM GlySar | ChEMBL. | 17887660 |
Papp (ADMET) | = 61.3 10^-8cm/s | Apparent permeability from apical to basolateral side of human Caco2 cells | ChEMBL. | 17887660 |
Papp (ADMET) | = 61.3 10^-8cm/s | Apparent permeability from apical to basolateral side of human Caco2 cells | ChEMBL. | 17887660 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.