Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | acetylcholinesterase | 0.0729 | 0.5 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0729 | 0.5 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0729 | 0.5 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0729 | 0.5 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0729 | 0.5 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0729 | 0.5 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0729 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0729 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0729 | 0.5 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0729 | 0.5 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0729 | 0.5 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0729 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC80 (functional) | = 0.0152 ug ml-1 | Antifungal activity against Candida parapsilosis ATCC 0306392 after 7 days by microbroth dilution method | ChEMBL. | 17335940 |
MIC80 (functional) | = 0.0625 ug ml-1 | Antifungal activity against Candida tropicalis after 7 days by microbroth dilution method | ChEMBL. | 17335940 |
MIC80 (functional) | = 0.0625 ug ml-1 | Antifungal activity against Trichophyton rubrum after 7 days by microbroth dilution method | ChEMBL. | 17335940 |
MIC80 (functional) | = 0.0625 ug ml-1 | Antifungal activity against Microsporum gypseum after 7 days by microbroth dilution method | ChEMBL. | 17335940 |
MIC80 (functional) | = 0.25 ug ml-1 | Antifungal activity against Candida albicans ATCC Y0109 after 24 hrs by microbroth dilution method | ChEMBL. | 17335940 |
MIC80 (functional) | = 0.25 ug ml-1 | Antifungal activity against Cryptococcus neoformans ATCC BLS108 after 72 hrs by microbroth dilution method | ChEMBL. | 17335940 |
MIC80 (functional) | = 0.25 ug ml-1 | Antifungal activity against Fonsecaea compacta after 7 days by microbroth dilution method | ChEMBL. | 17335940 |
MIC80 (functional) | = 0.25 ug ml-1 | Antifungal activity against Candida albicans ATCC Y0109 after 24 hrs by microbroth dilution method | ChEMBL. | 17335940 |
MIC80 (functional) | = 0.25 ug ml-1 | Antifungal activity against Cryptococcus neoformans ATCC BLS108 after 72 hrs by microbroth dilution method | ChEMBL. | 17335940 |
MIC80 (functional) | = 4 ug ml-1 | Antifungal activity against Aspergillus fumigatus after 7 days by microbroth dilution method | ChEMBL. | 17335940 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.