Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0441 | 0.0441 |
Schistosoma mansoni | tyrosine kinase | 0.0204 | 0.2447 | 0.2447 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.017 | 0.0086 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0278 | 0.3386 | 0.3386 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0278 | 0.3386 | 1 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0074 | 0.081 | 0.2392 |
Onchocerca volvulus | 0.0023 | 0.017 | 0.2103 | |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0278 | 0.3386 | 0.3386 |
Entamoeba histolytica | NAD(FAD)-dependent dehydrogenase, putative | 0.0074 | 0.081 | 1 |
Echinococcus multilocularis | fibroblast growth factor receptor 4 | 0.0204 | 0.2447 | 0.2447 |
Echinococcus multilocularis | neuroglian | 0.003 | 0.0255 | 0.0255 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0074 | 0.081 | 0.081 |
Treponema pallidum | NADH oxidase | 0.0278 | 0.3386 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0074 | 0.081 | 0.0731 |
Mycobacterium tuberculosis | Possible dehydrogenase/reductase | 0.0074 | 0.081 | 0.0731 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.017 | 0.2103 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0179 | 0.0179 |
Echinococcus granulosus | roundabout 2 | 0.003 | 0.0255 | 0.0255 |
Plasmodium falciparum | thioredoxin reductase | 0.0803 | 1 | 1 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0024 | 0.0179 | 0.0179 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0803 | 1 | 1 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0074 | 0.081 | 0.2392 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0278 | 0.3386 | 0.333 |
Plasmodium falciparum | glutathione reductase | 0.0278 | 0.3386 | 0.3386 |
Plasmodium falciparum | glutathione reductase | 0.0803 | 1 | 1 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0803 | 1 | 1 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0074 | 0.081 | 0.081 |
Plasmodium falciparum | thioredoxin reductase | 0.0278 | 0.3386 | 0.3386 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0074 | 0.081 | 0.081 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.017 | 0.017 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.081 | 0.2392 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0204 | 0.2455 | 0.2455 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0672 | 0.8358 | 0.8358 |
Toxoplasma gondii | thioredoxin reductase | 0.0803 | 1 | 1 |
Leishmania major | trypanothione reductase | 0.0803 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.017 | 0.0503 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3386 | 0.3386 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0278 | 0.3386 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0179 | 0.0179 |
Giardia lamblia | Glycerol-3-phosphate dehydrogenase | 0.0074 | 0.081 | 0.2392 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0441 | 0.0441 |
Echinococcus multilocularis | glutamate synthase | 0.0074 | 0.081 | 0.081 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.017 | 0.017 |
Plasmodium falciparum | ferrodoxin reductase-like protein | 0.0074 | 0.081 | 0.081 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0024 | 0.0179 | 0.0179 |
Echinococcus granulosus | basic fibroblast growth factor receptor 1 A | 0.0204 | 0.2447 | 0.2447 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0278 | 0.3386 | 1 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0074 | 0.081 | 0.081 |
Mycobacterium tuberculosis | Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) | 0.0074 | 0.081 | 0.0731 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3386 | 0.3386 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.017 | 0.0503 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0803 | 1 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0803 | 1 | 1 |
Mycobacterium leprae | THIOREDOXIN TRXC (TRX) (MPT46) | 0.0074 | 0.081 | 0.2392 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0441 | 0.0441 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0074 | 0.081 | 0.081 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.017 | 0.0503 |
Echinococcus granulosus | geminin | 0.0165 | 0.1961 | 0.1961 |
Schistosoma mansoni | sulfide quinone reductase | 0.0074 | 0.081 | 0.081 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0074 | 0.081 | 0.081 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3386 | 0.3272 |
Mycobacterium ulcerans | dehydrogenase | 0.0074 | 0.081 | 0.2392 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.017 | 0.2103 |
Giardia lamblia | Thioredoxin reductase | 0.0074 | 0.081 | 0.2392 |
Brugia malayi | Thioredoxin reductase | 0.0803 | 1 | 1 |
Toxoplasma gondii | selenide, water dikinase | 0.0074 | 0.081 | 0.081 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0097 | 0.0097 |
Wolbachia endosymbiont of Brugia malayi | NADPH-dependent glutamate synthase beta chain | 0.0074 | 0.081 | 0.2392 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0074 | 0.081 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0097 | 0.0097 |
Entamoeba histolytica | thioredoxin reductase, putative | 0.0074 | 0.081 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.017 | 0.0503 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0074 | 0.081 | 0.0731 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase-like protein, putative | 0.0074 | 0.081 | 0.081 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0278 | 0.3386 | 0.3386 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0074 | 0.081 | 0.2392 |
Mycobacterium tuberculosis | NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) | 0.0074 | 0.081 | 0.0731 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0074 | 0.081 | 0.2392 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0278 | 0.3386 | 0.3386 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.081 | 0.0651 |
Mycobacterium leprae | Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) | 0.0074 | 0.081 | 0.2392 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0074 | 0.081 | 0.081 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.081 | 0.081 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0803 | 1 | 1 |
Plasmodium vivax | NAD(P)H-dependent glutamate synthase, putative | 0.0074 | 0.081 | 0.081 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0255 | 0.0255 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0278 | 0.3386 | 0.333 |
Chlamydia trachomatis | thioredoxin reductase | 0.0074 | 0.081 | 0.2392 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0074 | 0.081 | 0.081 |
Echinococcus multilocularis | basic fibroblast growth factor receptor 1 A | 0.0204 | 0.2447 | 0.2447 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0074 | 0.081 | 0.081 |
Mycobacterium ulcerans | thioredoxin reductase TrxB2 | 0.0074 | 0.081 | 0.2392 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0278 | 0.3386 | 0.3386 |
Giardia lamblia | Glutamate synthase | 0.0074 | 0.081 | 0.2392 |
Mycobacterium tuberculosis | Probable thioredoxin reductase TrxB2 (TRXR) (TR) | 0.0074 | 0.081 | 0.0731 |
Treponema pallidum | oxidoreductase | 0.0074 | 0.081 | 0.2392 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0074 | 0.081 | 0.081 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0097 | 0.0097 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.017 | 0.0503 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0278 | 0.3386 | 0.3386 |
Plasmodium falciparum | type II NADH:ubiquinone oxidoreductase | 0.0074 | 0.081 | 0.081 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0097 | 0.0097 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0672 | 0.8358 | 0.8358 |
Mycobacterium ulcerans | monoxygenase | 0.0074 | 0.081 | 0.2392 |
Mycobacterium ulcerans | ferredoxin reductase | 0.0074 | 0.081 | 0.2392 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0074 | 0.081 | 0.081 |
Entamoeba histolytica | disulphide oxidoreductase, putative | 0.0074 | 0.081 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0074 | 0.081 | 0.0731 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.081 | 0.0651 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0074 | 0.081 | 0.081 |
Loa Loa (eye worm) | glutathione reductase | 0.0803 | 1 | 1 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0074 | 0.081 | 0.081 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0278 | 0.3386 | 0.3386 |
Echinococcus granulosus | neuroglian | 0.003 | 0.0255 | 0.0255 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3386 | 0.3386 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0074 | 0.081 | 0.081 |
Mycobacterium leprae | PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) | 0.0074 | 0.081 | 0.2392 |
Echinococcus granulosus | glutamate synthase | 0.0074 | 0.081 | 0.081 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0278 | 0.3386 | 0.3386 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0179 | 0.0179 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.017 | 0.0503 |
Leishmania major | 2,4-dienoyl-coa reductase fadh1, putative | 0.0074 | 0.081 | 0.0651 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0074 | 0.081 | 0.081 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0074 | 0.081 | 0.081 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0074 | 0.081 | 0.081 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.081 | 0.081 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.017 | 0.2103 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0179 | 0.0179 |
Leishmania major | 2,4-dienoyl-coa reductase-like protein | 0.0074 | 0.081 | 0.0651 |
Trypanosoma brucei | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0074 | 0.081 | 0.081 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0278 | 0.3386 | 0.3386 |
Treponema pallidum | thioredoxin reductase (trxB) | 0.0074 | 0.081 | 0.2392 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0278 | 0.3386 | 0.3386 |
Schistosoma mansoni | glutamate synthase | 0.0074 | 0.081 | 0.081 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0278 | 0.3386 | 0.3386 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.1961 | 0.1961 |
Schistosoma mansoni | glutamate synthase | 0.0074 | 0.081 | 0.081 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0097 | 0.0097 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0024 | 0.0179 | 0.0179 |
Schistosoma mansoni | glutamate synthase | 0.0074 | 0.081 | 0.081 |
Leishmania major | NADH dehydrogenase, putative | 0.0074 | 0.081 | 0.0651 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0278 | 0.3386 | 0.3386 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0074 | 0.081 | 0.081 |
Brugia malayi | glutamate synthase | 0.0074 | 0.081 | 0.081 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0074 | 0.081 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0074 | 0.081 | 0.0731 |
Schistosoma mansoni | cell adhesion molecule | 0.0024 | 0.0179 | 0.0179 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3386 | 0.3386 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0278 | 0.3386 | 0.3386 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0097 | 0.0097 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0278 | 0.3386 | 0.3386 |
Mycobacterium tuberculosis | Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) | 0.0074 | 0.081 | 0.0731 |
Wolbachia endosymbiont of Brugia malayi | thioredoxin reductase | 0.0074 | 0.081 | 0.2392 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0278 | 0.3386 | 0.3386 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0278 | 0.3386 | 1 |
Echinococcus granulosus | Immunoglobulin | 0.0024 | 0.0179 | 0.0179 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0074 | 0.081 | 0.081 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.017 | 0.0503 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.081 | 0.2392 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.081 | 0.2392 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.017 | 0.017 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0074 | 0.081 | 0.2392 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0074 | 0.081 | 0.2392 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0441 | 0.0441 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3386 | 0.3386 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0097 | 0.0097 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.081 | 0.0651 |
Wolbachia endosymbiont of Brugia malayi | thioredoxin reductase | 0.0074 | 0.081 | 0.2392 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.021 | 0.2524 | 0.2524 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0074 | 0.081 | 0.2392 |
Plasmodium vivax | ferrodoxin reductase, putative | 0.0074 | 0.081 | 0.081 |
Schistosoma mansoni | nephrin | 0.003 | 0.0255 | 0.0255 |
Mycobacterium tuberculosis | Probable reductase | 0.0074 | 0.081 | 0.0731 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0441 | 0.0441 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0179 | 0.0179 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0441 | 0.0441 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0803 | 1 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.0803 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0179 | 0.0179 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.081 | 0.2392 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0097 | 0.0286 |
Trichomonas vaginalis | dihydrolipoamide dehydrogenase, putative | 0.0074 | 0.081 | 0.2392 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0074 | 0.081 | 0.081 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0441 | 0.0441 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0097 | 0.0012 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.017 | 0.0086 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.1961 | 0.1961 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.017 | 0.017 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0026 | 0.0206 | 0.0206 |
Loa Loa (eye worm) | TK protein kinase | 0.021 | 0.2524 | 0.2524 |
Mycobacterium tuberculosis | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0074 | 0.081 | 0.0731 |
Plasmodium falciparum | NAD(P)H-dependent glutamate synthase, putative | 0.0074 | 0.081 | 0.081 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0074 | 0.081 | 0.2392 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0672 | 0.8358 | 0.8358 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.017 | 0.017 |
Echinococcus granulosus | twitchin | 0.003 | 0.0255 | 0.0255 |
Trypanosoma cruzi | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0074 | 0.081 | 0.081 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.081 | 0.2392 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.081 | 0.081 |
Mycobacterium leprae | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0074 | 0.081 | 0.2392 |
Entamoeba histolytica | pyridine nucleotide-disulfide oxidoreductase family protein | 0.0074 | 0.081 | 1 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0278 | 0.3386 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0278 | 0.3386 | 0.3386 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0278 | 0.3386 | 1 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0024 | 0.0179 | 0.0179 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0278 | 0.3386 | 0.3272 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh | 0.0074 | 0.081 | 0.2392 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0441 | 0.0441 |
Echinococcus multilocularis | Immunoglobulin | 0.0024 | 0.0179 | 0.0179 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0074 | 0.081 | 0.081 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3386 | 0.3272 |
Trypanosoma brucei | NADH dehydrogenase | 0.0074 | 0.081 | 0.081 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.017 | 0.017 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0278 | 0.3386 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0179 | 0.0179 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0278 | 0.3386 | 1 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0024 | 0.0179 | 0.0179 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.081 | 0.081 |
Echinococcus granulosus | defective proboscis extension response | 0.0024 | 0.0179 | 0.0179 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0074 | 0.081 | 0.081 |
Mycobacterium ulcerans | hypothetical protein | 0.0074 | 0.081 | 0.2392 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0278 | 0.3386 | 0.3272 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0074 | 0.081 | 0.081 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0074 | 0.081 | 0.081 |
Echinococcus multilocularis | roundabout 2 | 0.003 | 0.0255 | 0.0255 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0074 | 0.081 | 0.081 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0278 | 0.3386 | 0.3386 |
Schistosoma mansoni | vesicular amine transporter | 0.0024 | 0.0179 | 0.0179 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0017 | 0.0097 | 0.0286 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.3386 | 0.3386 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0074 | 0.081 | 0.081 |
Echinococcus multilocularis | geminin | 0.0165 | 0.1961 | 0.1961 |
Mycobacterium ulcerans | NADPH dependent 2,4-dienoyl-CoA reductase FadH | 0.0074 | 0.081 | 0.2392 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0074 | 0.081 | 0.081 |
Trypanosoma brucei | trypanothione reductase | 0.0803 | 1 | 1 |
Onchocerca volvulus | 0.0074 | 0.081 | 1 | |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.017 | 0.0503 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0278 | 0.3386 | 0.333 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0278 | 0.3386 | 1 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0074 | 0.081 | 0.081 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0204 | 0.2455 | 0.2455 |
Echinococcus granulosus | fibroblast growth factor receptor 4 | 0.0204 | 0.2447 | 0.2447 |
Schistosoma mansoni | sulfide quinone reductase | 0.0074 | 0.081 | 0.081 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0074 | 0.081 | 0.081 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.017 | 0.0503 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprB | 0.0074 | 0.081 | 0.2392 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0074 | 0.081 | 0.2392 |
Echinococcus multilocularis | Immunoglobulin | 0.0024 | 0.0179 | 0.0179 |
Mycobacterium ulcerans | NADH dehydrogenase | 0.0074 | 0.081 | 0.2392 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase fadh1, putative | 0.0074 | 0.081 | 0.081 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0024 | 0.0179 | 0.0179 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0179 | 0.0179 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.081 | 0.2392 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0074 | 0.081 | 0.0731 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0074 | 0.081 | 0.081 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0255 | 0.0255 |
Trypanosoma brucei | 2,4-dienoyl-coa reductase-like protein | 0.0074 | 0.081 | 0.081 |
Plasmodium vivax | type II NADH:ubiquinone oxidoreductase, putative | 0.0074 | 0.081 | 0.081 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.017 | 0.0503 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0441 | 0.0441 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh1 | 0.0074 | 0.081 | 0.2392 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0278 | 0.3386 | 0.333 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0278 | 0.3386 | 1 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0074 | 0.081 | 1 |
Mycobacterium ulcerans | glutamate synthase subunit beta | 0.0074 | 0.081 | 0.2392 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0026 | 0.0206 | 0.0206 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | 0 | Antibacterial activity against Escherichia coli at 0.125% (w/v) concentration after 24 hrs by disc diffusion method | ChEMBL. | 17331623 |
Activity (functional) | 0 | Antifungal activity against Penicillium funiculosum at 0.5% (w/v) concentration by disc diffusion method | ChEMBL. | 17331623 |
Activity (functional) | = 0.3 % | Induction of chromosomal aberration in human peripheral blood leukocytes assessed as number of chromatid breaks at 20 ug/mL after 24 hrs | ChEMBL. | 17331623 |
Activity (functional) | = 0.6 % | Induction of chromosomal aberration in human peripheral blood leukocytes assessed as number of chromatid gaps at 20 ug/mL after 24 hrs | ChEMBL. | 17331623 |
IZ (functional) | = 2 mm | Antibacterial activity against Escherichia coli at 0.25% (w/v) concentration after 24 hrs by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 2 mm | Antifungal activity against Aspergillus flavus at 0.5% (w/v) concentration by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 2 mm | Antifungal activity against Fusarium oxysporum at 0.5% (w/v) concentration by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 2 mm | Antibacterial activity against Escherichia coli at 0.25% (w/v) concentration after 24 hrs by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 3 mm | Antifungal activity against Penicillium funiculosum at 1% (w/v) concentration by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 3 mm | Antifungal activity against Alternaria macrospora at 0.5% (w/v) concentration by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 4 mm | Antibacterial activity against Aeromonas hydrophila at 0.125% (w/v) concentration after 24 hrs by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 4 mm | Antifungal activity against Aspergillus flavus at 1% (w/v) concentration by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 5 mm | Antibacterial activity against Salmonella typhi at 0.125% (w/v) concentration after 24 hrs by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 6 mm | Antibacterial activity against Escherichia coli at 0.5% (w/v) concentration by after 24 hrs by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 6 mm | Antifungal activity against Alternaria macrospora at 1% (w/v) concentration by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 6 mm | Antifungal activity against Fusarium oxysporum at 1% (w/v) concentration by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 6 mm | Antibacterial activity against Escherichia coli at 0.5% (w/v) concentration by after 24 hrs by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 7 mm | Antibacterial activity against Aeromonas hydrophila at 0.25% (w/v) concentration after 24 hrs by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 7 mm | Antibacterial activity against Salmonella typhi at 0.25% (w/v) concentration after 24 hrs by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 8 mm | Antifungal activity against Aspergillus flavus at 2% (w/v) concentration by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 10 mm | Antifungal activity against Penicillium funiculosum at 2% (w/v) concentration by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 10 mm | Antifungal activity against Alternaria macrospora at 2% (w/v) concentration by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 10 mm | Antifungal activity against Fusarium oxysporum at 2% (w/v) concentration by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 11 mm | Antibacterial activity against Aeromonas hydrophila at 0.5% (w/v) concentration after 24 hrs by disc diffusion method | ChEMBL. | 17331623 |
IZ (functional) | = 12 mm | Antibacterial activity against Salmonella typhi at 0.5% (w/v) concentration after 24 hrs by disc diffusion method | ChEMBL. | 17331623 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.