Detailed information for compound 435821

Basic information

Technical information
  • TDR Targets ID: 435821
  • Name: 3-chloro-N-[4-chloro-2-[(4-chlorophenyl)carba moyl]phenyl]-4-[[2-dimethylaminoethyl(methyl) amino]methyl]thiophene-2-carboxamide
  • MW: 539.905 | Formula: C24H25Cl3N4O2S
  • H donors: 2 H acceptors: 2 LogP: 5.91 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: CN(Cc1csc(c1Cl)C(=O)Nc1ccc(cc1C(=O)Nc1ccc(cc1)Cl)Cl)CCN(C)C
  • InChi: 1S/C24H25Cl3N4O2S/c1-30(2)10-11-31(3)13-15-14-34-22(21(15)27)24(33)29-20-9-6-17(26)12-19(20)23(32)28-18-7-4-16(25)5-8-18/h4-9,12,14H,10-11,13H2,1-3H3,(H,28,32)(H,29,33)
  • InChiKey: QDKKSLVXVLBPRN-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • 3-chloro-N-[4-chloro-2-[(4-chloroanilino)-oxomethyl]phenyl]-4-[[2-dimethylaminoethyl(methyl)amino]methyl]-2-thiophenecarboxamide
  • 3-chloro-N-[4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl]-4-[(2-dimethylaminoethyl-methylamino)methyl]thiophene-2-carboxamide
  • 3-chloro-N-[4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl]-4-[(2-dimethylaminoethyl-methyl-amino)methyl]thiophene-2-carboxamide
  • 3-chloro-N-[4-chloro-2-[[(4-chlorophenyl)amino]-oxomethyl]phenyl]-4-[(2-dimethylaminoethyl-methylamino)methyl]-2-thiophenecarboxamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor X Starlite/ChEMBL References
Homo sapiens coagulation factor II (thrombin) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis hypothetical protein 0.0014 0.0139 0.036
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0759 0.1959
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0185 0.2929 0.7569
Echinococcus granulosus neurogenic locus notch protein 0.0011 0.0086 0.0222
Loa Loa (eye worm) hypothetical protein 0.0009 0.0047 0.0122
Toxoplasma gondii P-type ATPase4, putative 0.001 0.0071 0.0062
Echinococcus granulosus lysine specific demethylase 5A 0.0008 0.0038 0.0099
Onchocerca volvulus 0.0044 0.0624 0.3986
Trichomonas vaginalis D-aminoacylase, putative 0.0022 0.026 0.0658
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Echinococcus granulosus cathepsin l1 0.0102 0.1566 0.4048
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0007 0.0013 0.0003
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0242 0.387 1
Brugia malayi Na,K-ATPase alpha subunit 0.0027 0.0348 0.0898
Trichomonas vaginalis A-type flavoprotein 0.0009 0.0047 0.0106
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0209 0.0541
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0007 0.0013 0.0033
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0008 0.0035 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Plasmodium vivax vivapain-2 0.0102 0.1566 0.4033
Giardia lamblia Hypothetical protein 0.0019 0.0209 0.0517
Echinococcus granulosus voltage gated potassium channel 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0034 0.0452 0.1169
Trypanosoma cruzi transcription factor btf3, putative 0.0008 0.0029 0.01
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0044 0.0617 0.1594
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0019 0.0209 0.0526
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0044 0.0617 0.1594
Entamoeba histolytica metallo-beta-lactamase family protein 0.0009 0.0047 0.0118
Schistosoma mansoni transient receptor potential channel 4 0.0008 0.0035 0.009
Echinococcus granulosus neuropeptide receptor A26 0.0146 0.2288 0.5912
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Loa Loa (eye worm) G-protein coupled receptor 0.0044 0.0617 0.1594
Echinococcus granulosus orexin receptor type 2 0.0044 0.0617 0.1594
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Entamoeba histolytica cysteine protease, putative 0.0019 0.0209 0.0537
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0044 0.0624 0.1613
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Plasmodium vivax hypothetical protein, conserved 0.0022 0.026 0.0649
Echinococcus multilocularis calcium transporting atpase 0.001 0.0071 0.0184
Echinococcus multilocularis protein jagged 1 0.0011 0.0086 0.0222
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0066 0.0978 0.2528
Trypanosoma cruzi cysteine peptidase, putative 0.0124 0.1928 1
Echinococcus granulosus slit 2 protein 0.0011 0.0086 0.0222
Loa Loa (eye worm) hypothetical protein 0.0034 0.0452 0.1169
Entamoeba histolytica type A flavoprotein, putative 0.0009 0.0047 0.0118
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0022 0.026 0.0672
Echinococcus multilocularis two pore calcium channel protein 1 0.0008 0.0035 0.009
Loa Loa (eye worm) ctsf protein 0.0102 0.1566 0.4048
Entamoeba histolytica hypothetical protein 0.0006 0.0006 0.0011
Brugia malayi hypothetical protein 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Echinococcus multilocularis peroxidasin 0.0016 0.0159 0.0411
Echinococcus granulosus cathepsin L 0.0019 0.0209 0.0541
Giardia lamblia Cathepsin B precursor 0.0019 0.0209 0.0517
Entamoeba histolytica hypothetical protein 0.0006 0.0006 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0019 0.0209 0.0526
Brugia malayi Calcium binding EGF domain containing protein 0.0016 0.0166 0.043
Plasmodium vivax unspecified product 0.0052 0.0759 0.1942
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0008 0.0035 0.0025
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0025
Toxoplasma gondii hypothetical protein 0.0008 0.0035 0.0025
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0022 0.026 0.0214
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0066 0.0978 0.2528
Echinococcus multilocularis neuropeptide s receptor 0.0146 0.2288 0.5912
Brugia malayi cathepsin L precursor 0.0019 0.0209 0.0541
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0009 0.0056 0.014
Onchocerca volvulus Putative cubilin 0.0011 0.0086 0.0549
Onchocerca volvulus 0.0021 0.0251 0.1599
Echinococcus granulosus ryanodine receptor 44f 0.0008 0.0035 0.009
Entamoeba histolytica cysteine protease, putative 0.0052 0.0759 0.1959
Echinococcus multilocularis geminin 0.0076 0.1142 0.2952
Brugia malayi hypothetical protein 0.0044 0.0617 0.1594
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.001 0.0071 0.0062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0209 0.0541
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0006 0.0006 0.0017
Echinococcus granulosus potassium voltage gated channel protein 0.0008 0.0035 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0019 0.0209 0.0526
Brugia malayi cation channel family protein 0.0008 0.0035 0.009
Trichomonas vaginalis D-aminoacylase, putative 0.0022 0.026 0.0658
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0044 0.0617 0.1594
Loa Loa (eye worm) ryanodine receptor 0.0008 0.0035 0.009
Brugia malayi Animal haem peroxidase family protein 0.0016 0.0159 0.0411
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Loa Loa (eye worm) ion channel NompC 0.0008 0.0035 0.009
Onchocerca volvulus 0.0102 0.1566 1
Echinococcus multilocularis fibrillin 1 0.0016 0.0166 0.043
Echinococcus granulosus exocyst complex component 2 0.0006 0.0006 0.0015
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0044 0.0617 0.1594
Leishmania major P-type ATPase, putative 0.001 0.0071 0.0223
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0008 0.0035 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0209 0.0526
Loa Loa (eye worm) PHD-finger family protein 0.0007 0.001 0.0025
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0009 0.0047 0.0122
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0066 0.0978 0.2516
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.026 0.1305
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0019 0.0209 0.0541
Brugia malayi G protein-coupled receptor F59B2.13 0.0044 0.0617 0.1594
Brugia malayi Animal haem peroxidase family protein 0.0016 0.0159 0.0411
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0029 0.006
Loa Loa (eye worm) G-protein coupled receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Schistosoma mansoni calcium-activated potassium channel 0.0008 0.0035 0.009
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.024 0.3833 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Trichomonas vaginalis apoptosis inducing factor, putative 0.0009 0.0047 0.0106
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0759 0.1959
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0066 0.0978 0.2509
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0009 0.0047 0.0122
Brugia malayi RE15519p 0.0044 0.0617 0.1594
Entamoeba histolytica metallo-beta-lactamase family protein 0.0009 0.0047 0.0118
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Onchocerca volvulus 0.0016 0.0159 0.1016
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0008 0.0035 0.003
Leishmania major hypothetical protein, conserved 0.0008 0.0035 0.003
Echinococcus multilocularis cathepsin L cysteine protease 0.0102 0.1566 0.4048
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.0009 0.0047 0.0194
Loa Loa (eye worm) hypothetical protein 0.0019 0.0209 0.0541
Brugia malayi cathepsin F-like cysteine proteinase 0.0034 0.0452 0.1169
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0209 0.0541
Onchocerca volvulus 0.0014 0.0139 0.0889
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0242 0.387 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0102 0.1566 0.4048
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0035 0.009
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.001 0.0071 0.0184
Schistosoma mansoni transient receptor potential channel 0.0008 0.0035 0.009
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0044 0.0617 0.1594
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.0617 0.1594
Schistosoma mansoni hypothetical protein 0.0009 0.0047 0.0122
Loa Loa (eye worm) hypothetical protein 0.0016 0.0166 0.043
Loa Loa (eye worm) hypothetical protein 0.0016 0.0166 0.043
Giardia lamblia Cathepsin B precursor 0.0019 0.0209 0.0517
Echinococcus multilocularis fat cadherin tumor suppressor 0.0011 0.0086 0.0222
Onchocerca volvulus 0.0026 0.0332 0.2119
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.0209 0.0541
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0066 0.0978 0.2528
Echinococcus multilocularis cathepsin L cysteine protease 0.0102 0.1566 0.4048
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0063 0.0931 0.2405
Echinococcus multilocularis cysteine protease 0.0102 0.1566 0.4048
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0044 0.0617 0.1594
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0008 0.0035 0.009
Toxoplasma gondii kringle domain-containing protein 0.0021 0.0251 0.0241
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0242 0.387 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0022 0.026 0.0672
Onchocerca volvulus 0.0022 0.026 0.166
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0053 0.0775 0.2003
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0008 0.0035 0.009
Echinococcus multilocularis somatostatin receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0066 0.0978 0.2528
Echinococcus granulosus G protein coupled receptor 139 0.0044 0.0617 0.1594
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0759 0.195
Loa Loa (eye worm) cathepsin B 0.0019 0.0209 0.0541
Onchocerca volvulus 0.0008 0.0035 0.0221
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1928 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0044 0.0617 0.1594
Brugia malayi neuropeptide F receptor 0.0044 0.0617 0.1594
Echinococcus granulosus transient receptor potential cation channel 0.0008 0.0035 0.009
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0035 0.009
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0063 0.0931 0.2405
Mycobacterium tuberculosis Possible penicillin-binding protein 0.014 0.2189 0.5659
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0056 0.0129
Echinococcus granulosus transient receptor potential gamma protein 0.0008 0.0035 0.009
Schistosoma mansoni myosin xvIII 0.0044 0.0617 0.1594
Echinococcus granulosus cathepsin L cysteine protease 0.0052 0.0759 0.1962
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0047 0.0106
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0027 0.0348 0.0898
Brugia malayi Dopamine receptor protein 1 0.0044 0.0617 0.1594
Onchocerca volvulus 0.0016 0.0159 0.1016
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0021 0.0251 0.0624
Mycobacterium tuberculosis Probable lipase LipD 0.0022 0.026 0.0563
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0242 0.387 1
Entamoeba histolytica cysteine protease, putative 0.0052 0.0759 0.1959
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.1566 0.4038
Echinococcus granulosus potassium voltage gated channel protein 0.0008 0.0035 0.009
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0044 0.0617 0.1594
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0209 0.1335
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Echinococcus granulosus transient receptor potential cation channel 0.0008 0.0035 0.009
Schistosoma mansoni neuropeptide F-like receptor 0.0044 0.0617 0.1594
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0009 0.0056 0.0239
Echinococcus granulosus PHD finger protein rhinoceros 0.0007 0.001 0.0025
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0242 0.387 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.026 0.0672
Leishmania major cathepsin L-like protease 0.0124 0.1928 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0044 0.0617 0.1594
Schistosoma mansoni notch 0.0011 0.0086 0.0222
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0008 0.0035 0.009
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0035 0.0074
Leishmania major calcium-translocating P-type ATPase 0.0009 0.0056 0.014
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0617 1 1
Echinococcus granulosus dro:myosuppressin receptor 0.0044 0.0617 0.1594
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0019 0.0209 0.0517
Loa Loa (eye worm) hypothetical protein 0.0007 0.0013 0.0033
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0034 0.0452 0.1169
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1928 1
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0016 0.0166 0.043
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.0009 0.0047 0.0194
Echinococcus granulosus calcium transporting atpase 0.001 0.0071 0.0184
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Brugia malayi E1-E2 ATPase family protein 0.0006 0.0002 0.0004
Entamoeba histolytica cysteine protease, putative 0.0019 0.0209 0.0537
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0063 0.0931 0.4802
Echinococcus multilocularis Tolloid protein 1 0.0016 0.0166 0.043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1928 1
Schistosoma mansoni opsin-like receptor 0.0044 0.0617 0.1594
Schistosoma mansoni cathepsin S (C01 family) 0.0019 0.0209 0.0541
Brugia malayi cathepsin F-like cysteine proteinase 0.0019 0.0209 0.0541
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Echinococcus multilocularis lysine specific demethylase 5A 0.0008 0.0032 0.0083
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.0009 0.0047 0.0194
Echinococcus multilocularis neurogenic locus protein delta 0.0011 0.0086 0.0222
Schistosoma mansoni cathepsin F (C01 family) 0.0102 0.1566 0.4048
Loa Loa (eye worm) hypothetical protein 0.0035 0.047 0.1213
Brugia malayi Papain family cysteine protease containing protein 0.0052 0.0759 0.1962
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0044 0.0617 0.1594
Plasmodium vivax unspecified product 0.0034 0.0452 0.1147
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0022 0.026 0.0672
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0223
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0044 0.0624 0.1613
Brugia malayi cathepsin L-like precursor 0.0068 0.1016 0.2626
Entamoeba histolytica type A flavoprotein, putative 0.0009 0.0047 0.0118
Echinococcus multilocularis nervana 2 0.0053 0.0775 0.2003
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0066 0.0978 0.2528
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Echinococcus multilocularis transcription factor btf3 0.0008 0.0029 0.0075
Onchocerca volvulus 0.0035 0.047 0.2998
Entamoeba histolytica cysteine protease, putative 0.0052 0.0759 0.1959
Toxoplasma gondii hypothetical protein 0.0063 0.0931 0.0922
Loa Loa (eye worm) hypothetical protein 0.0016 0.0166 0.043
Schistosoma mansoni neuropeptide receptor 0.0044 0.0617 0.1594
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0019 0.0209 0.0541
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0047 0.0106
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0008 0.0035 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0019 0.0209 0.0541
Echinococcus granulosus voltage dependent calcium channel 0.0053 0.0764 0.1974
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0019 0.0209 0.0517
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0044 0.0624 0.1613
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0027 0.0348 0.0876
Brugia malayi hypothetical protein 0.0009 0.0047 0.0122
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0209 0.0526
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0377 0.6069 1
Brugia malayi Pre-SET motif family protein 0.0046 0.066 0.1706
Trypanosoma cruzi transcription factor btf3, putative 0.0008 0.0029 0.01
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0059 0.0872 0.4497
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.0009 0.0047 0.0194
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0027 0.0348 0.0898
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0019 0.0209 0.0949
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0617 0.1594
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Trypanosoma cruzi cruzipain precursor, putative 0.0034 0.0452 0.2307
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.1566 0.4038
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0019 0.0209 0.0517
Schistosoma mansoni cpg binding protein 0.0007 0.0012 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Toxoplasma gondii preprocathepsin c precursor, putative 0.0019 0.0209 0.02
Leishmania major calcium motive p-type ATPase, putative 0.001 0.0071 0.0223
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0063 0.0931 0.2402
Brugia malayi Plexin repeat family protein 0.0035 0.047 0.1213
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0759 0.1959
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0008 0.0035 0.009
Trypanosoma brucei cysteine peptidase C (CPC) 0.0019 0.0209 0.104
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0008 0.0035 0.009
Loa Loa (eye worm) voltage-gated potassium channel 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0035 0.009
Brugia malayi Cathepsin L-like precursor 0.0102 0.1566 0.4048
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Echinococcus multilocularis potassium voltage gated channel protein 0.0008 0.0035 0.009
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0019 0.0209 0.0517
Onchocerca volvulus 0.0007 0.0013 0.0081
Brugia malayi plexin A 0.0041 0.0573 0.1482
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0011 0.0086 0.0549
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0044 0.0617 0.1594
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0008 0.0035 0.009
Brugia malayi GCC2 and GCC3 family protein 0.0011 0.0086 0.0222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Mycobacterium tuberculosis Probable esterase LipL 0.0022 0.026 0.0563
Onchocerca volvulus Slit protein homolog 0.0011 0.0086 0.0549
Trypanosoma brucei hypothetical protein, conserved 0.0063 0.0931 0.4802
Echinococcus multilocularis peregrin 0.0007 0.001 0.0025
Onchocerca volvulus 0.0102 0.1566 1
Schistosoma mansoni cathepsin F (C01 family) 0.0102 0.1566 0.4048
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.0617 0.1594
Trypanosoma brucei calcium-translocating P-type ATPase 0.001 0.0071 0.0321
Echinococcus multilocularis exocyst complex component 2 0.0006 0.0006 0.0015
Loa Loa (eye worm) TYRA-2 protein 0.0044 0.0617 0.1594
Echinococcus granulosus neurogenic locus notch protein 4 0.0011 0.0086 0.0222
Onchocerca volvulus Putative hydrolase PNKD 0.0009 0.0047 0.03
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0066 0.0978 0.2525
Brugia malayi hypothetical protein 0.0014 0.0139 0.036
Plasmodium vivax SET domain protein, putative 0.0007 0.0013 0.0008
Entamoeba histolytica cysteine protease, putative 0.0019 0.0209 0.0537
Toxoplasma gondii NAC domain-containing protein 0.0008 0.0029 0.002
Echinococcus granulosus transient receptor potential cation channel 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Brugia malayi AKH receptor 0.0044 0.0617 0.1594
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1928 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0166 0.043
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.001 0.0071 0.0321
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0008 0.0035 0.009
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Brugia malayi EGF-like domain containing protein 0.0011 0.0086 0.0222
Trypanosoma brucei calcium motive p-type ATPase, putative 0.001 0.0071 0.0321
Loa Loa (eye worm) hypothetical protein 0.0053 0.0775 0.2003
Brugia malayi cathepsin B-like cysteine proteinase 0.0019 0.0209 0.0541
Loa Loa (eye worm) hypothetical protein 0.0014 0.0139 0.036
Toxoplasma gondii EGF family domain-containing protein 0.0011 0.0086 0.0076
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0035 0.009
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0008 0.0035 0.009
Echinococcus granulosus neuropeptide receptor 0.0044 0.0617 0.1594
Brugia malayi Blistered cuticle protein 3 0.0016 0.0159 0.0411
Onchocerca volvulus Dual oxidase homolog 0.0016 0.0159 0.1016
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0044 0.0617 0.1594
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0063 0.0931 0.2405
Echinococcus multilocularis neuropeptides capa receptor 0.0044 0.0617 0.1594
Echinococcus granulosus peregrin 0.0007 0.001 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.026 0.1305
Plasmodium falciparum serine repeat antigen 2 0.0019 0.0209 0.0517
Echinococcus granulosus transcription factor collier 0.0006 0.0006 0.0015
Echinococcus multilocularis neuropeptide receptor 0.0044 0.0617 0.1594
Plasmodium falciparum serine repeat antigen 9 0.0019 0.0209 0.0517
Toxoplasma gondii cathepsin B 0.0019 0.0209 0.02
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0063 0.0931 0.2393
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.001 0.0071 0.0184
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Schistosoma mansoni transient receptor potential channel 0.0008 0.0035 0.009
Brugia malayi Papain family cysteine protease containing protein 0.0102 0.1566 0.4048
Echinococcus granulosus neuropeptide FF receptor 2 0.0044 0.0617 0.1594
Schistosoma mansoni hypothetical protein 0.0011 0.0086 0.0222
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0008 0.0035 0.009
Echinococcus multilocularis neurogenic locus protein delta 0.0011 0.0086 0.0222
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Echinococcus granulosus neuropeptides capa receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis shaker cognate 0.0008 0.0035 0.009
Onchocerca volvulus Cathepsin L homolog 0.0102 0.1566 1
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0008 0.0035 0.013
Plasmodium vivax vivapain-1 0.0052 0.0759 0.1942
Schistosoma mansoni amine GPCR 0.0044 0.0617 0.1594
Onchocerca volvulus 0.0009 0.0047 0.03
Echinococcus multilocularis transcription factor collier 0.0006 0.0006 0.0015
Onchocerca volvulus 0.0022 0.026 0.166
Loa Loa (eye worm) hypothetical protein 0.002 0.0232 0.0601
Entamoeba histolytica cysteine proteinase 1, putative 0.0052 0.0759 0.1959
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0035 0.009
Loa Loa (eye worm) metallo-beta-lactamase superfamily protein 0.0009 0.0047 0.0122
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Brugia malayi Cathepsin L-like precursor 0.0068 0.1016 0.2626
Echinococcus granulosus fibropellin Ia 0.0011 0.0086 0.0222
Echinococcus multilocularis neurogenic locus notch protein 0.0011 0.0086 0.0222
Leishmania major cathepsin L-like protease 0.0124 0.1928 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0209 0.0526
Schistosoma mansoni amine GPCR 0.0044 0.0617 0.1594
Echinococcus multilocularis voltage gated potassium channel 0.0008 0.0035 0.009
Brugia malayi beta-lactamase 0.0022 0.026 0.0672
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0044 0.0617 0.1594
Plasmodium vivax calcium-transporting ATPase, putative 0.001 0.0071 0.016
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0019 0.0209 0.0537
Brugia malayi Serotonin receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis fmrfamide receptor 0.0044 0.0617 0.1594
Brugia malayi jmjC domain containing protein 0.0008 0.0038 0.0099
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0009 0.0056 0.0046
Loa Loa (eye worm) notch protein 0.0011 0.0086 0.0222
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0022 0.026 0.0563
Brugia malayi Tachykinin-like peptides receptor 99D 0.0044 0.0617 0.1594
Onchocerca volvulus 0.0063 0.0931 0.5942
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Entamoeba histolytica cysteine protease, putative 0.0019 0.0209 0.0537
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis sex peptide receptor 0.0044 0.0617 0.1594
Giardia lamblia Cysteine protease 0.0019 0.0209 0.0517
Echinococcus granulosus notch 0.0011 0.0086 0.0222
Brugia malayi Cadherin domain containing protein 0.0011 0.0086 0.0222
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.001 0.0071 0.0169
Plasmodium vivax vivapain-2 0.0102 0.1566 0.4033
Brugia malayi GnHR receptor homolog 0.0044 0.0617 0.1594
Giardia lamblia Cysteine protease 0.0019 0.0209 0.0517
Onchocerca volvulus 0.0044 0.0617 0.3939
Onchocerca volvulus 0.0102 0.1566 1
Schistosoma mansoni fibrocystin l 0.0006 0.0006 0.0015
Schistosoma mansoni hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) 0.0009 0.0047 0.0122
Onchocerca volvulus 0.0044 0.0617 0.3939
Brugia malayi Transient-receptor-potential like protein 0.0008 0.0035 0.009
Entamoeba histolytica hypothetical protein 0.0019 0.0209 0.0537
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0052 0.0759 0.3909
Brugia malayi neuropeptide F receptor 0.0044 0.0617 0.1594
Echinococcus granulosus ETHE1 protein 0.0009 0.0047 0.0122
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Giardia lamblia Cathepsin B precursor 0.0019 0.0209 0.0517
Entamoeba histolytica hypothetical protein 0.0006 0.0006 0.0011
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0021 0.0254 0.0657
Brugia malayi Membrane calcium atpase protein 3 0.001 0.0071 0.0184
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0019 0.0209 0.0517
Schistosoma mansoni plexin 0.002 0.0232 0.0601
Schistosoma mansoni hypothetical protein 0.0006 0.0006 0.0015
Leishmania major metallo-beta-lactamase family protein-like protein 0.0009 0.0047 0.0095
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.001 0.0071 0.0184
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.0617 0.1594
Brugia malayi beta-lactamase family protein 0.0022 0.026 0.0672
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0377 0.6069 0.6051
Trichomonas vaginalis beta lactamase domain, putative 0.0009 0.0047 0.0106
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Echinococcus granulosus Tolloid protein 1 0.0016 0.0166 0.043
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0008 0.0035 0.009
Leishmania major metallo-beta-lactamase family-like protein 0.0009 0.0047 0.0095
Plasmodium falciparum cysteine proteinase falcipain 3 0.0102 0.1566 0.4033
Leishmania major calcium-transporting ATPase, putative 0.001 0.0071 0.0223
Loa Loa (eye worm) hypothetical protein 0.0185 0.2929 0.7569
Plasmodium falciparum serine repeat antigen 5 0.0019 0.0209 0.0517
Schistosoma mansoni opsin-like receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0185 0.2929 0.7569
Schistosoma mansoni microtubule-associated protein tau 0.0153 0.2409 0.6224
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0019 0.0209 0.0517
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0242 0.387 1
Echinococcus granulosus protein jagged 2 0.0011 0.0086 0.0222
Echinococcus multilocularis allatostatin A receptor 0.0044 0.0617 0.1594
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0063 0.0931 0.2405
Trypanosoma cruzi hypothetical protein, conserved 0.0063 0.0931 0.4802
Brugia malayi Kringle domain containing protein 0.0021 0.0251 0.0647
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0008 0.0035 0.009
Trypanosoma cruzi glyoxalase II 0.0009 0.0047 0.0194
Toxoplasma gondii hypothetical protein 0.0045 0.0631 0.0623
Brugia malayi ORL1-like opioid receptor 0.0044 0.0617 0.1594
Schistosoma mansoni two-pore calcium channel 0.0008 0.0035 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Echinococcus granulosus neuropeptide Y receptor 0.0044 0.0617 0.1594
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0022 0.027 0.0224
Echinococcus granulosus tachykinin peptides receptor 99D 0.0044 0.0617 0.1594
Brugia malayi EGF-like domain containing protein 0.0011 0.0086 0.0222
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.0209 0.0541
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0185 0.2929 0.7569
Echinococcus multilocularis neuropeptide receptor 0.0044 0.0617 0.1594
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0059 0.0872 0.4497
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0044 0.0617 0.1594
Echinococcus granulosus laminin 0.0016 0.0166 0.043
Echinococcus multilocularis g protein coupled receptor 0.0044 0.0617 0.1594
Trichomonas vaginalis D-aminoacylase, putative 0.0022 0.026 0.0658
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0242 0.387 1
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0009 0.0056 0.0239
Onchocerca volvulus 0.0044 0.0617 0.3939
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.0209 0.0541
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1928 1
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Schistosoma mansoni biogenic amine receptor 0.0044 0.0617 0.1594
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0022 0.026 0.0563
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.001 0.0071 0.0321
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0044 0.0617 0.1594
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0035 0.009
Toxoplasma gondii ABC1 family protein 0.0022 0.026 0.0251
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.0009 0.0047 0.0194
Echinococcus multilocularis short transient receptor potential channel 6 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Plasmodium falciparum cysteine proteinase falcipain 1 0.0052 0.0759 0.1942
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0008 0.0035 0.009
Echinococcus granulosus nervana 2 0.0053 0.0775 0.2003
Echinococcus multilocularis potassium voltage gated channel protein 0.0008 0.0035 0.009
Leishmania major hypothetical protein, conserved 0.0009 0.0047 0.0095
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Plasmodium falciparum calcium-transporting ATPase 0.001 0.0071 0.016
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0021 0.0248 0.0641
Schistosoma mansoni hypothetical protein 0.0011 0.0086 0.0222
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.001 0.0071 0.016
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0759 0.1959
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Brugia malayi EGF-like domain containing protein 0.0011 0.0086 0.0222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0053 0.0775 0.2003
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0053 0.0775 0.2003
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0016 0.0166 0.043
Trypanosoma cruzi cysteine proteinase, putative 0.0052 0.0759 0.3909
Loa Loa (eye worm) hypothetical protein 0.0009 0.0047 0.0122
Onchocerca volvulus Cathepsin F homolog 0.0102 0.1566 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Echinococcus multilocularis dnaJ subfamily B 0.0091 0.1388 0.3586
Echinococcus granulosus nervana 2 0.0044 0.0624 0.1613
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0102 0.1566 0.4048
Loa Loa (eye worm) Notch2 0.0011 0.0086 0.0222
Entamoeba histolytica hypothetical protein 0.0008 0.0029 0.0071
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0008 0.0035 0.009
Brugia malayi Peroxidasin 0.0016 0.0159 0.0411
Echinococcus multilocularis microtubule associated protein 2 0.0153 0.2409 0.6224
Brugia malayi G-protein coupled receptor 0.0044 0.0617 0.1594
Onchocerca volvulus 0.0006 0.0006 0.0041
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0009 0.0056 0.0129
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0617 1 1
Entamoeba histolytica cysteine proteinase 2 0.0052 0.0759 0.1959
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0008 0.0035 0.009
Echinococcus multilocularis g protein coupled receptor 0.0044 0.0617 0.1594
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Trichomonas vaginalis beta lactamase domain, putative 0.0009 0.0047 0.0106
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0053 0.0775 0.2003
Brugia malayi larval opioid receptor 0.0044 0.0617 0.1594
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0019 0.0209 0.0517
Brugia malayi CXXC zinc finger family protein 0.0006 0.0006 0.0016
Schistosoma mansoni voltage-gated ion channel 0.0008 0.0035 0.009
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0063 0.0931 0.2386
Echinococcus granulosus dnaJ subfamily B 0.0091 0.1388 0.3586
Echinococcus multilocularis potassium large conductance calcium activated 0.0008 0.0035 0.009
Echinococcus granulosus transient receptor potential cation channel 0.0008 0.0035 0.009
Schistosoma mansoni hypothetical protein 0.0076 0.1142 0.2952
Echinococcus granulosus neuropeptide receptor 0.0044 0.0617 0.1594
Trypanosoma cruzi glyoxalase II 0.0009 0.0047 0.0194
Brugia malayi G protein-coupled receptor 0.0044 0.0617 0.1594
Brugia malayi Cathepsin L-like precursor 0.0102 0.1566 0.4048
Brugia malayi metallo-beta-lactamase superfamily protein 0.0009 0.0047 0.0122
Onchocerca volvulus Chorion peroxidase homolog 0.0016 0.0159 0.1016
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0102 0.1566 0.4038
Schistosoma mansoni neuropeptide receptor 0.0044 0.0617 0.1594
Brugia malayi hypothetical protein 0.0044 0.0617 0.1594
Toxoplasma gondii transporter, cation channel family protein 0.0053 0.0764 0.0755
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0209 0.0526
Echinococcus granulosus somatostatin receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0044 0.0617 0.1594
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0035 0.009
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0056 0.0129
Loa Loa (eye worm) ICD-1 protein 0.0008 0.0029 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0209 0.0526
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0044 0.0617 0.1594
Brugia malayi IPT/TIG domain containing protein 0.0006 0.0006 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0007 0.0013 0.0033
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0056 0.0129
Onchocerca volvulus 0.0011 0.0086 0.0549
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0019 0.0209 0.0541
Onchocerca volvulus 0.0053 0.0775 0.495
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0044 0.0617 0.1594
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0242 0.387 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0022 0.026 0.0672
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Onchocerca volvulus 0.0044 0.0617 0.3939
Echinococcus granulosus g-protein coupled receptor 0.0044 0.0617 0.1594
Echinococcus granulosus cpg binding protein 0.0007 0.0012 0.0032
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.0759 0.3909
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0242 0.387 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Brugia malayi cathepsin L-like cysteine proteinase 0.0019 0.0209 0.0541
Plasmodium falciparum serine repeat antigen 1 0.0019 0.0209 0.0517
Brugia malayi hypothetical protein 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Echinococcus multilocularis neuropeptide Y receptor 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0053 0.0764 0.1974
Echinococcus granulosus plexin a4 0.0041 0.0573 0.1482
Echinococcus granulosus histone lysine methyltransferase setb 0.0007 0.0013 0.0033
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.001 0.0071 0.0024
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0008 0.0035 0.009
Echinococcus granulosus sex peptide receptor 0.0044 0.0617 0.1594
Entamoeba histolytica cysteine protease, putative 0.0102 0.1566 0.4045
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0044 0.0617 0.1594
Giardia lamblia Cathepsin L-like protease 0.0019 0.0209 0.0517
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0019 0.0209 0.0517
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0035 0.009
Echinococcus multilocularis zinc phosphodiesterase 0.0009 0.0047 0.0122
Echinococcus multilocularis notch 0.0011 0.0086 0.0222
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0007 0.0013 0.0033
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0056 0.0129
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0068 0.1016 0.2626
Echinococcus multilocularis protein jagged 2 0.0011 0.0086 0.0222
Echinococcus granulosus 7TM GPCR rhodopsin 0.0044 0.0617 0.1594
Echinococcus granulosus voltage dependent calcium channel 0.0185 0.2929 0.7569
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.1566 0.4038
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0044 0.0617 0.3939
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0044 0.0617 0.1594
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0027 0.0348 0.0898
Echinococcus granulosus nervana 2 0.0053 0.0775 0.2003
Echinococcus granulosus delta-like protein 1 0.0011 0.0086 0.0222
Brugia malayi Cadherin domain containing protein 0.0011 0.0086 0.0222
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1928 1
Schistosoma mansoni hypothetical protein 0.0014 0.0139 0.036
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.009 0.1377 0.7131
Brugia malayi Cathepsin L-like precursor 0.0102 0.1566 0.4048
Loa Loa (eye worm) hypothetical protein 0.0014 0.0139 0.036
Schistosoma mansoni transient receptor potential channel 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0045 0.0631 0.1632
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Onchocerca volvulus 0.0016 0.0159 0.1016
Schistosoma mansoni hypothetical protein 0.0076 0.1142 0.2952
Loa Loa (eye worm) hypothetical protein 0.0022 0.026 0.0672
Brugia malayi Delta serrate ligand family protein 0.0011 0.0086 0.0222
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0019 0.0209 0.104
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0009 0.0056 0.0239
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.024 0.3833 0.3804
Schistosoma mansoni amine GPCR 0.0044 0.0617 0.1594
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0008 0.0035 0.009
Toxoplasma gondii hypothetical protein 0.0008 0.0035 0.0025
Schistosoma mansoni hypothetical protein 0.0091 0.1388 0.3586
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Loa Loa (eye worm) animal heme peroxidase 0.0016 0.0159 0.0411
Schistosoma mansoni laminin gamma-3 chain 0.0011 0.0086 0.0222
Leishmania major cathepsin L-like protease 0.0102 0.1566 0.8097
Giardia lamblia Cysteine protease 0.0019 0.0209 0.0517
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Echinococcus multilocularis cathepsin L 0.0019 0.0209 0.0541
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Onchocerca volvulus 0.0011 0.0086 0.0549
Giardia lamblia Cathepsin L precursor 0.0019 0.0209 0.0517
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0029 0.006
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.001 0.0071 0.0062
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0009 0.0056 0.0144
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1928 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0044 0.0617 0.1594
Onchocerca volvulus 0.0053 0.0765 0.4882
Brugia malayi hypothetical protein 0.0044 0.0617 0.1594
Mycobacterium tuberculosis Conserved protein 0.0022 0.026 0.0563
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.001 0.0071 0.0184
Echinococcus granulosus short transient receptor potential channel 6 0.0008 0.0035 0.009
Plasmodium falciparum basic transcription factor 3b, putative 0.0008 0.0029 0.005
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0014 0.0139 0.036
Loa Loa (eye worm) hypothetical protein 0.0034 0.0452 0.1169
Giardia lamblia Cathepsin L-like protease 0.0019 0.0209 0.0517
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0008 0.0035 0.009
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0019 0.0209 0.0517
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0066 0.0978 0.5049
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0019 0.0209 0.0526
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Brugia malayi Cathepsin L-like precursor 0.0068 0.1016 0.2626
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Onchocerca volvulus 0.0009 0.0047 0.03
Loa Loa (eye worm) beta-lactamase 0.0022 0.026 0.0672
Brugia malayi Calcium binding EGF domain containing protein 0.0011 0.0086 0.0222
Schistosoma mansoni ATPase 0.0009 0.0056 0.0144
Echinococcus multilocularis transfer RNA-Gly 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Brugia malayi EGF-like domain containing protein 0.0011 0.0086 0.0222
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0035 0.009
Schistosoma mansoni jumonji/arid domain-containing protein 0.0008 0.0038 0.0099
Loa Loa (eye worm) hypothetical protein 0.0022 0.026 0.0672
Echinococcus multilocularis tissue type plasminogen activator 0.0021 0.0251 0.0647
Brugia malayi hypothetical protein 0.0044 0.0617 0.1594
Echinococcus granulosus sodium channel protein 0.0008 0.0035 0.009
Echinococcus granulosus sodium leak channel non selective protein 0.0008 0.0035 0.009
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Echinococcus granulosus short transient receptor potential channel 6 0.0008 0.0035 0.009
Plasmodium vivax serine-repeat antigen (SERA) 0.0019 0.0209 0.0517
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Trypanosoma cruzi major cysteine proteinase, putative 0.0019 0.0209 0.104
Loa Loa (eye worm) hypothetical protein 0.0045 0.0631 0.1632
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0044 0.0617 0.1594
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0182 0.047
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Brugia malayi Calcium binding EGF domain containing protein 0.0011 0.0086 0.0222
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0242 0.387 1
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0035 0.009
Schistosoma mansoni cathepsin s 0.0034 0.0452 0.1169
Echinococcus multilocularis fibropellin Ia 0.0011 0.0086 0.0222
Giardia lamblia Rab geranylgeranyltransferase 0.0063 0.0931 0.2386
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0044 0.0624 0.1613
Brugia malayi Animal haem peroxidase family protein 0.0016 0.0159 0.0411
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0009 0.0056 0.0144
Echinococcus multilocularis cathepsin b 0.0019 0.0209 0.0541
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0019 0.0209 0.0517
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1928 1
Giardia lamblia Metallo-beta-lactamase superfamily protein 0.0009 0.0047 0.0097
Schistosoma mansoni notch 0.0011 0.0086 0.0222
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0617 1 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0008 0.0035 0.009
Toxoplasma gondii transporter, cation channel family protein 0.0008 0.0035 0.0025
Loa Loa (eye worm) hypothetical protein 0.0014 0.0139 0.036
Onchocerca volvulus Huntingtin homolog 0.0027 0.0347 0.2216
Loa Loa (eye worm) sema domain-containing protein 0.0014 0.0139 0.036
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.0617 0.1594
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0019 0.0209 0.0517
Toxoplasma gondii hydroxyacylglutathione hydrolase 0.0009 0.0047 0.0038
Echinococcus multilocularis cpg binding protein 0.0007 0.0012 0.0032
Loa Loa (eye worm) hydroxyacylglutathione hydrolase 0.0009 0.0047 0.0122
Loa Loa (eye worm) animal heme peroxidase 0.0016 0.0159 0.0411
Brugia malayi Dopamine receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis nervana 2 0.0053 0.0775 0.2003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0209 0.0541
Entamoeba histolytica cysteine protease, putative 0.0052 0.0759 0.1959
Brugia malayi putative neuropeptide receptor 0.0044 0.0617 0.1594
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0011 0.0086 0.0222
Brugia malayi follicle stimulating hormone receptor 0.0095 0.1452 0.3753
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0008 0.0035 0.0025
Toxoplasma gondii transporter, cation channel family protein 0.0008 0.0035 0.0025
Schistosoma mansoni voltage-dependent calcium channel 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0009 0.0047 0.0122
Loa Loa (eye worm) hypothetical protein 0.0068 0.1016 0.2626
Trypanosoma brucei transcription factor BTF3, putative 0.0008 0.0029 0.01
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0019 0.0209 0.0541
Echinococcus granulosus cathepsin b 0.0019 0.0209 0.0541
Loa Loa (eye worm) hypothetical protein 0.0006 0.0006 0.0015
Onchocerca volvulus Peroxidase homolog 0.0016 0.0159 0.1016
Schistosoma mansoni hypothetical protein 0.0044 0.0617 0.1594
Entamoeba histolytica cysteine protease, putative 0.0052 0.0759 0.1959
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0759 0.3909
Loa Loa (eye worm) blistered cuticle protein 3 0.0016 0.0159 0.0411
Loa Loa (eye worm) hypothetical protein 0.0014 0.0139 0.036
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0019 0.0209 0.0517
Loa Loa (eye worm) neuropeptide F receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis serotonin receptor 0.0044 0.0617 0.1594
Onchocerca volvulus Peroxidasin homolog 0.0016 0.0159 0.1016
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0066 0.0978 0.5049
Brugia malayi hypothetical protein 0.0027 0.0347 0.0897
Schistosoma mansoni egf-like domain protein 0.0016 0.0166 0.043
Brugia malayi jmjC domain containing protein 0.0021 0.0254 0.0657
Schistosoma mansoni cell polarity protein 0.0011 0.0086 0.0222
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0008 0.0035 0.013
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0102 0.1566 0.4038
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis neuropeptide Y receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis conserved hypothetical protein 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0068 0.1016 0.2626
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0016 0.0166 0.043
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0179 0.2841 0.7338
Echinococcus multilocularis orexin receptor type 2 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Leishmania major hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative 0.0009 0.0047 0.0095
Schistosoma mansoni transmemberane protein 0.0053 0.0775 0.2003
Brugia malayi notch-like transmembrane receptor 0.0011 0.0086 0.0222
Entamoeba histolytica cysteine proteinase, putative 0.0102 0.1566 0.4045
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0185 0.2929 0.7569
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Plasmodium falciparum serine repeat antigen 7 0.0019 0.0209 0.0517
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0066 0.0978 0.5049
Brugia malayi G-protein coupled receptor 0.0044 0.0617 0.1594
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0009 0.0056 0.012
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Echinococcus granulosus beta LACTamase domain containing family member 0.0022 0.026 0.0672
Loa Loa (eye worm) jmjC domain-containing protein 0.0014 0.0124 0.0321
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Schistosoma mansoni neuropeptide F-like receptor 0.0044 0.0617 0.1594
Giardia lamblia Encystation-specific protease 0.0019 0.0209 0.0517
Entamoeba histolytica hypothetical protein 0.0006 0.0006 0.0011
Plasmodium vivax unspecified product 0.0009 0.0047 0.0097
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0063 0.0931 0.2405
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0019 0.0209 0.0541
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.001 0.0071 0.0184
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0209 0.0526
Schistosoma mansoni adenoreceptor 0.0044 0.0617 0.1594
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0025
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0066 0.0978 0.4999
Loa Loa (eye worm) hypothetical protein 0.0006 0.0006 0.0015
Brugia malayi Animal haem peroxidase family protein 0.0016 0.0159 0.0411
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Plasmodium falciparum serine repeat antigen 3 0.0019 0.0209 0.0517
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0007 0.001 0.0025
Loa Loa (eye worm) animal heme peroxidase 0.0016 0.0159 0.0411
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.001 0.0071 0.018
Onchocerca volvulus Neuropeptide F receptor homolog 0.0044 0.0617 0.3939
Onchocerca volvulus 0.0044 0.0617 0.3939
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0035 0.009
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.001 0.0071 0.0184
Brugia malayi Cyclic-nucleotide gated cation channel 0.0008 0.0035 0.009
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0008 0.0035 0.009
Toxoplasma gondii cathepsin CPC2 0.0019 0.0209 0.02
Onchocerca volvulus 0.0102 0.1566 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Loa Loa (eye worm) hydroxyacylglutathione hydrolase cytoplasmic 0.0009 0.0047 0.0122
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0044 0.0617 0.1594
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Onchocerca volvulus 0.0044 0.0617 0.3939
Brugia malayi beta-lactamase family protein 0.0022 0.026 0.0672
Schistosoma mansoni hypothetical protein 0.0021 0.0251 0.0647
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0019 0.0209 0.0526
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0063 0.0931 0.4802
Echinococcus granulosus g protein coupled receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis cathepsin b 0.0019 0.0209 0.0541
Schistosoma mansoni 3-dehydroquinate synthase 0.024 0.3833 0.9904
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0044 0.0617 0.1594
Entamoeba histolytica cysteine protease, putative 0.0019 0.0209 0.0537
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Echinococcus granulosus shaker cognate 0.0008 0.0035 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0209 0.0526
Giardia lamblia Hypothetical protein 0.0019 0.0209 0.0517
Trichomonas vaginalis beta lactamase domain, putative 0.0009 0.0047 0.0106
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0009 0.0047 0.0122
Echinococcus granulosus protein jagged 2 0.0011 0.0086 0.0222
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.1566 0.4038
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0009 0.0056 0.014
Brugia malayi cation channel family protein 0.0008 0.0035 0.009
Plasmodium falciparum serine repeat antigen 6 0.0019 0.0209 0.0517
Trichomonas vaginalis esterase, putative 0.0022 0.026 0.0658
Mycobacterium tuberculosis Probable lipase LipE 0.0022 0.026 0.0563
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.1566 0.4038
Echinococcus granulosus nervana 2 0.0044 0.0624 0.1613
Echinococcus multilocularis sodium channel protein 0.0015 0.0143 0.0369
Onchocerca volvulus 0.0044 0.0617 0.3939
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0102 0.1566 0.4048
Onchocerca volvulus 0.0068 0.1016 0.6487
Schistosoma mansoni opsin-like receptor 0.0044 0.0617 0.1594
Entamoeba histolytica alkyl sulfatase, putative 0.0009 0.0047 0.0118
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0026 0.0332 0.0286
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0044 0.0617 0.1594
Schistosoma mansoni hypothetical protein 0.0014 0.0139 0.036
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0019 0.0209 0.104
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.0617 0.1594
Loa Loa (eye worm) voltage-dependent calcium channel 0.0053 0.0764 0.1974
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0185 0.2929 0.7569
Entamoeba histolytica alkyl sulfatase, putative 0.0009 0.0047 0.0118
Echinococcus granulosus peptide allatostatin:somatostatin 0.0044 0.0617 0.1594
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.0053 0.0775 0.2003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0617 0.1594
Echinococcus multilocularis neural cadherin 0.0011 0.0086 0.0222
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1928 1
Leishmania major cleavage and polyadenylation specificity factor, putative 0.0009 0.0047 0.0095
Onchocerca volvulus 0.0011 0.0086 0.0549
Onchocerca volvulus Peroxidase homolog 0.0016 0.0159 0.1016
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0063 0.0931 0.4749
Loa Loa (eye worm) fibroinase 0.0102 0.1566 0.4048
Entamoeba histolytica hypothetical protein, conserved 0.0009 0.0047 0.0118
Echinococcus multilocularis two pore calcium channel protein 2 0.0008 0.0035 0.009
Echinococcus multilocularis voltage dependent calcium channel 0.0185 0.2929 0.7569
Echinococcus granulosus neuropeptides capa receptor 0.0044 0.0617 0.1594
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0009 0.0056 0.0239
Leishmania major hypothetical protein, conserved 0.0022 0.026 0.1217
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Echinococcus multilocularis plexin a4 0.0041 0.0573 0.1482
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0008 0.0035 0.009
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0019 0.0209 0.0517
Plasmodium vivax unspecified product 0.0019 0.0209 0.0517
Entamoeba histolytica cell surface protease gp63, putative 0.0006 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0063 0.0931 0.4802
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0053 0.0775 0.2003
Plasmodium falciparum cytosolic glyoxalase II 0.0009 0.0047 0.0097
Loa Loa (eye worm) voltage-gated potassium channel 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0063 0.0931 0.2405
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0019 0.0209 0.0541
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Onchocerca volvulus 0.0044 0.0617 0.3939
Loa Loa (eye worm) neuropeptide F receptor 0.0044 0.0617 0.1594
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0022 0.026 0.0672
Onchocerca volvulus 0.0102 0.1566 1
Echinococcus granulosus peroxidasin 0.0016 0.0159 0.0411
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0209 0.0526
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis hydroxyacylglutathione hydrolase 0.0009 0.0047 0.0122
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0044 0.0617 0.1594
Brugia malayi hypothetical protein 0.0044 0.0617 0.1594
Entamoeba histolytica cysteine protease, putative 0.0052 0.0759 0.1959
Trichomonas vaginalis beta lactamase domain, putative 0.0009 0.0047 0.0106
Brugia malayi Cathepsin L-like precursor 0.0034 0.0452 0.1169
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0377 0.6069 1
Leishmania major hypothetical protein, unknown function 0.0008 0.0035 0.003
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0023 0.0286 0.0739
Plasmodium falciparum serine repeat antigen 8 0.0019 0.0209 0.0517
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0053 0.0775 0.2003
Echinococcus granulosus neurogenic locus notch protein 0.0011 0.0086 0.0222
Mycobacterium ulcerans esterase/lipase LipP 0.0022 0.026 0.0214
Loa Loa (eye worm) hypothetical protein 0.0009 0.0047 0.0122
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.001 0.0071 0.0184
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0027 0.0348 0.0898
Echinococcus multilocularis semaphorin 5B 0.0014 0.0139 0.036
Entamoeba histolytica transcription factor BTF3, putative 0.0008 0.0029 0.0071
Echinococcus granulosus transient receptor potential cation channel 0.0008 0.0035 0.009
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0019 0.0209 0.0517
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0019 0.0209 0.0526
Brugia malayi Serotonin receptor 0.0044 0.0617 0.1594
Onchocerca volvulus 0.0022 0.026 0.166
Schistosoma mansoni biogenic amine (5HT) receptor 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0014 0.0139 0.036
Brugia malayi Cathepsin L-like precursor 0.0102 0.1566 0.4048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Entamoeba histolytica cysteine protease, putative 0.0052 0.0759 0.1959
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0617 0.1594
Giardia lamblia Cathepsin B precursor 0.0019 0.0209 0.0517
Onchocerca volvulus 0.0044 0.0617 0.3939
Echinococcus granulosus semaphorin 1A 0.0014 0.0139 0.036
Onchocerca volvulus 0.0102 0.1566 1
Schistosoma mansoni slit 0.0011 0.0086 0.0222
Brugia malayi Papain family cysteine protease containing protein 0.0052 0.0759 0.1962
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Schistosoma mansoni hypothetical protein 0.0011 0.0086 0.0222
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0617 0.1594
Giardia lamblia Cathepsin B precursor 0.0019 0.0209 0.0517
Echinococcus granulosus potassium voltage gated channel protein 0.0008 0.0035 0.009
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0008 0.0035 0.009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0759 0.3909
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.0009 0.0047 0.0194
Schistosoma mansoni plexin 0.0035 0.047 0.1213
Echinococcus multilocularis neuropeptide FF receptor 2 0.0044 0.0617 0.1594
Echinococcus granulosus cathepsin b 0.0019 0.0209 0.0541
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0008 0.0035 0.009
Schistosoma mansoni vesicular amine transporter 0.0008 0.0038 0.0099
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.0209 0.0541
Giardia lamblia Cathepsin B precursor 0.0019 0.0209 0.0517
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Echinococcus granulosus potassium voltage gated channel protein 0.0008 0.0035 0.009
Trypanosoma cruzi hypothetical protein, conserved 0.0063 0.0931 0.4802
Entamoeba histolytica cysteine protease, putative 0.0019 0.0209 0.0537
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0047 0.0106
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0008 0.0035 0.009
Brugia malayi Protein kinase domain containing protein 0.0023 0.0278 0.0719
Brugia malayi fibroinase precursor 0.0019 0.0209 0.0541
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0044 0.0617 0.1594
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.0209 0.0541
Toxoplasma gondii hypothetical protein 0.0179 0.2841 0.2834
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0009 0.0056 0.014
Brugia malayi Calcium binding EGF domain containing protein 0.0011 0.0086 0.0222
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0044 0.0617 0.1594
Echinococcus multilocularis potassium voltage gated channel protein 0.0008 0.0035 0.009
Onchocerca volvulus Neurogenic locus notch homolog 0.0011 0.0086 0.0549
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.001 0.0071 0.0169
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0127 0.0329
Schistosoma mansoni amine GPCR 0.0044 0.0617 0.1594
Echinococcus granulosus jumonji domain containing protein 0.0009 0.0052 0.0134
Brugia malayi Sema domain containing protein 0.0014 0.0139 0.036
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.0053 0.0775 0.2003
Entamoeba histolytica metallo-beta-lactamase family protein 0.0009 0.0047 0.0118
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.001 0.0071 0.0184
Schistosoma mansoni biogenic amine (5HT) receptor 0.0044 0.0617 0.1594
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0047 0.0106
Mycobacterium leprae conserved hypothetical protein 0.0022 0.026 0.0214
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0035 0.009
Schistosoma mansoni hypothetical protein 0.0007 0.001 0.0025
Echinococcus multilocularis fmrfamide receptor 0.0044 0.0617 0.1594
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0029 0.006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0007 0.0013 0.0033
Mycobacterium ulcerans 3-dehydroquinate synthase 0.024 0.3833 0.3804
Echinococcus granulosus transient receptor potential cation channel 0.0008 0.0035 0.009
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0008 0.0035 0.009
Loa Loa (eye worm) calcium channel 0.0185 0.2929 0.7569
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0019 0.0209 0.0517
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0021 0.0254 0.0657
Brugia malayi Bromodomain containing protein 0.0007 0.001 0.0025
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0008 0.0035 0.009
Brugia malayi Sema domain containing protein 0.0014 0.0139 0.036
Brugia malayi ethe1-prov protein 0.0009 0.0047 0.0122
Onchocerca volvulus Alhambra homolog 0.0007 0.001 0.0061
Schistosoma mansoni ATPase 0.0009 0.0056 0.0144
Schistosoma mansoni cathepsin B (C01 family) 0.0019 0.0209 0.0541
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0066 0.0978 0.2528
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Echinococcus granulosus neuropeptide Y receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis transient receptor potential gamma protein 0.0008 0.0035 0.009
Brugia malayi ion channel NompC 0.0008 0.0035 0.009
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0066 0.0978 0.2516
Echinococcus granulosus potassium large conductance calcium activated 0.0008 0.0035 0.009
Echinococcus granulosus hypothetical protein 0.0008 0.0035 0.009
Giardia lamblia Cathepsin L precursor 0.0019 0.0209 0.0517
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0016 0.0166 0.043
Echinococcus granulosus geminin 0.0076 0.1142 0.2952
Onchocerca volvulus Arrow homolog 0.0016 0.0166 0.1061
Echinococcus granulosus g protein coupled receptor 0.0044 0.0617 0.1594
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0019 0.0209 0.0526
Brugia malayi Melatonin receptor type 1A 0.0044 0.0617 0.1594
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0027 0.0347 0.0897
Echinococcus granulosus 7tm_1 domain containing protein 0.0044 0.0617 0.1594
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.0209 0.0541
Schistosoma mansoni zinc phosphodiesterase 0.0009 0.0047 0.0122
Entamoeba histolytica cysteine protease, putative 0.0052 0.0759 0.1959
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Entamoeba histolytica cysteine protease, putative 0.0052 0.0759 0.1959
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.0617 0.1594
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0009 0.0056 0.014
Giardia lamblia Rab geranylgeranyltransferase 0.0242 0.387 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Brugia malayi Cathepsin L-like precursor 0.0102 0.1566 0.4048
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0209 0.0526
Echinococcus granulosus cathepsin L cysteine proteinase 0.0102 0.1566 0.4048
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0008 0.0035 0.009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1928 1
Giardia lamblia High cysteine protein 0.0011 0.0086 0.0198
Toxoplasma gondii calcium binding egf domain-containing protein 0.0016 0.0166 0.0157
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0063 0.0931 0.4802
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Brugia malayi DNA-binding protein LAG-1 0.0006 0.0006 0.0015
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0044 0.0617 0.1594
Brugia malayi cathepsin Z-like cysteine proteinase 0.0019 0.0209 0.0541
Schistosoma mansoni histamine h1 receptor 0.0044 0.0617 0.1594
Echinococcus granulosus potassium voltage gated channel protein 0.0008 0.0035 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0019 0.0209 0.0526
Brugia malayi beta-NAC-like protein 0.0008 0.0029 0.0075
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Echinococcus multilocularis neurogenic locus notch protein 4 0.0011 0.0086 0.0222
Loa Loa (eye worm) hypothetical protein 0.0027 0.0347 0.0897
Trichomonas vaginalis beta lactamase domain, putative 0.0009 0.0047 0.0106
Echinococcus granulosus neurogenic locus protein delta 0.0011 0.0086 0.0222
Onchocerca volvulus 0.0044 0.0617 0.3939
Echinococcus granulosus Na:K ATPase alpha subunit 0.0027 0.0348 0.0898
Trypanosoma brucei hydroxyacylglutathione hydrolase, putative 0.0009 0.0047 0.0194
Loa Loa (eye worm) hypothetical protein 0.0242 0.387 1
Schistosoma mansoni notch 0.0011 0.0086 0.0222
Echinococcus granulosus neuropeptide s receptor 0.0146 0.2288 0.5912
Onchocerca volvulus Hydroxyacylglutathione hydrolase, mitochondrial homolog 0.0009 0.0047 0.03
Echinococcus multilocularis sodium leak channel non selective protein 0.0008 0.0035 0.009
Echinococcus multilocularis slit 2 protein 0.0011 0.0086 0.0222
Trypanosoma brucei metallo-beta-lactamase-like protein, putative 0.0009 0.0047 0.0194
Loa Loa (eye worm) hypothetical protein 0.0022 0.026 0.0672
Trypanosoma brucei cleavage and polyadenylation specificity factor subunit, putative 0.0009 0.0047 0.0194
Brugia malayi Cathepsin L-like precursor 0.0102 0.1566 0.4048
Chlamydia trachomatis dehyroquinate synthase 0.024 0.3833 0.3804
Loa Loa (eye worm) cysteine protease 0.0102 0.1566 0.4048
Brugia malayi Pre-SET motif family protein 0.0007 0.0013 0.0033
Onchocerca volvulus 0.0044 0.0617 0.3939
Loa Loa (eye worm) hypothetical protein 0.0006 0.0006 0.0015
Echinococcus granulosus neural cadherin 0.0011 0.0086 0.0222
Trypanosoma cruzi cysteine peptidase, putative 0.0034 0.0452 0.2307
Giardia lamblia Cathepsin L precursor 0.0019 0.0209 0.0517
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0518
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.1566 0.4038
Brugia malayi EGF-like domain containing protein 0.0011 0.0086 0.0222
Echinococcus granulosus calcium transporting ATPase type 2C member 0.001 0.0071 0.0184
Schistosoma mansoni zinc phosphodiesterase 0.0009 0.0047 0.0122
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.1016 0.2614
Echinococcus granulosus voltage gated hydrogen channel 1 0.0008 0.0035 0.009
Brugia malayi hypothetical protein 0.0044 0.0617 0.1594
Brugia malayi olfactory channel protein osm-9 0.0008 0.0035 0.009
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0008 0.0035 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0617 0.1594
Trichomonas vaginalis penicillin-binding protein, putative 0.0022 0.026 0.0658
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0209 0.0541
Schistosoma mansoni alpha-1 adrenergic receptor 0.0044 0.0617 0.1594
Loa Loa (eye worm) CXXC zinc finger family protein 0.0006 0.0006 0.0016
Schistosoma mansoni neuropeptide receptor 0.0044 0.0617 0.1594
Toxoplasma gondii histone lysine methyltransferase SET1 0.0012 0.0104 0.0094
Echinococcus multilocularis g protein coupled receptor 0.0044 0.0617 0.1594
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.001 0.0071 0.0184
Leishmania major cathepsin L-like protease 0.0124 0.1928 1
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.001 0.0071 0.0184
Echinococcus multilocularis ryanodine receptor 44f 0.0008 0.0035 0.009
Schistosoma mansoni peroxidasin 0.0016 0.0159 0.0411
Schistosoma mansoni hypothetical protein 0.002 0.0232 0.0601
Schistosoma mansoni ryanodine receptor related 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0209 0.0526
Echinococcus multilocularis protein jagged 1 0.0011 0.0086 0.0222
Echinococcus multilocularis nervana 2 0.0044 0.0624 0.1613
Brugia malayi hypothetical protein 0.0016 0.0159 0.0411
Echinococcus granulosus serotonin receptor 0.0044 0.0617 0.1594
Echinococcus granulosus hydroxyacylglutathione hydrolase 0.0009 0.0047 0.0122
Mycobacterium ulcerans hypothetical protein 0.0022 0.026 0.0214
Schistosoma mansoni hypothetical protein 0.0011 0.0086 0.0222
Leishmania major cathepsin L-like protease 0.0102 0.1566 0.8097
Echinococcus multilocularis jumonji domain containing protein 0.0009 0.0052 0.0134
Entamoeba histolytica cysteine proteinase, putative 0.0102 0.1566 0.4045
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0022 0.026 0.0563
Echinococcus multilocularis laminin 0.0016 0.0166 0.043
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0452 0.1169
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0185 0.2929 0.7569
Onchocerca volvulus 0.0044 0.0617 0.3939
Giardia lamblia Cysteine protease 0.0019 0.0209 0.0517
Loa Loa (eye worm) plexin A 0.0041 0.0573 0.1482
Echinococcus multilocularis G-protein coupled receptor, putative 0.0044 0.0617 0.1594
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0007 0.001 0.0025
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0008 0.0035 0.009
Toxoplasma gondii calcium binding egf domain-containing protein 0.0016 0.0166 0.0157
Giardia lamblia Cathepsin L precursor 0.0019 0.0209 0.0517
Onchocerca volvulus 0.0044 0.0617 0.3939
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Schistosoma mansoni cathepsin C 0.0019 0.0209 0.0541
Echinococcus granulosus microtubule associated protein 2 0.0153 0.2409 0.6224
Schistosoma mansoni jumonji/arid domain-containing protein 0.0008 0.0038 0.0099
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0035 0.009
Giardia lamblia Cathepsin L precursor 0.0019 0.0209 0.0517
Schistosoma mansoni neuropeptide receptor 0.0044 0.0617 0.1594
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0052 0.0759 0.1962
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0185 0.2929 0.7569
Loa Loa (eye worm) hypothetical protein 0.0053 0.0775 0.2003
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0009 0.0056 0.012
Echinococcus granulosus cathepsin L 0.0052 0.0759 0.1962
Giardia lamblia Cathepsin L precursor 0.0019 0.0209 0.0517
Echinococcus granulosus alpha 1A adrenergic receptor 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0019 0.0209 0.0541
Onchocerca volvulus 0.0011 0.0086 0.0549
Schistosoma mansoni voltage-gated cation channel 0.0185 0.2929 0.7569
Mycobacterium ulcerans lipase LipD 0.0022 0.026 0.0214
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0008 0.0035 0.009
Echinococcus granulosus allatostatin A receptor 0.0044 0.0617 0.1594
Toxoplasma gondii cathepsin CPL 0.0102 0.1566 0.1558
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.0209 0.0541
Schistosoma mansoni biogenic amine receptor 0.0044 0.0617 0.1594
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0035 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0047 0.0106
Entamoeba histolytica cysteine proteinase, putative 0.0068 0.1016 0.2623
Loa Loa (eye worm) hypothetical protein 0.0102 0.1566 0.4048
Mycobacterium leprae Probable lipase LipE 0.0022 0.026 0.0214
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0019 0.0209 0.0537
Brugia malayi Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. 0.0009 0.0047 0.0122
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.0209 0.0541
Leishmania major cathepsin L-like protease 0.0102 0.1566 0.8097
Echinococcus multilocularis voltage gated potassium channel 0.0008 0.0035 0.009
Echinococcus granulosus cysteine protease 0.0052 0.0759 0.1962
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Echinococcus granulosus transcription factor btf3 0.0008 0.0029 0.0075
Leishmania major hypothetical protein, conserved 0.0021 0.0251 0.1167
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0066 0.0978 0.2528
Entamoeba histolytica protein kinase domain containing protein 0.0008 0.0034 0.0083
Schistosoma mansoni hypothetical protein 0.0044 0.0617 0.1594
Echinococcus multilocularis dro:myosuppressin receptor 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0016 0.0166 0.043
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0019 0.0209 0.0541
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0052 0.0759 0.1962
Loa Loa (eye worm) hypothetical protein 0.0019 0.0209 0.0541
Schistosoma mansoni hypothetical protein 0.0011 0.0086 0.0222
Onchocerca volvulus Huntingtin homolog 0.0027 0.0347 0.2216
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0052 0.0759 0.1962
Loa Loa (eye worm) hypothetical protein 0.0021 0.0251 0.0647
Schistosoma mansoni transcription factor btf3 0.0008 0.0029 0.0075
Trypanosoma cruzi cysteine peptidase, putative 0.0124 0.1928 1
Echinococcus multilocularis g-protein coupled receptor 0.0044 0.0617 0.1594
Echinococcus granulosus fmrfamide receptor 0.0044 0.0617 0.1594
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0046 0.066 0.1706
Schistosoma mansoni hypothetical protein 0.0009 0.0047 0.0122
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0022 0.026 0.0672
Loa Loa (eye worm) voltage-gated calcium channel 0.0008 0.0035 0.009
Mycobacterium ulcerans beta-lactamase 0.0022 0.026 0.0214
Onchocerca volvulus 0.0044 0.0617 0.3939
Brugia malayi cathepsin Z-like cysteine proteinase 0.0019 0.0209 0.0541
Onchocerca volvulus 0.0044 0.0617 0.3939
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.1566 0.4038
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Echinococcus multilocularis serotonin receptor 0.0044 0.0617 0.1594
Mycobacterium tuberculosis Conserved protein 0.0022 0.026 0.0563
Echinococcus granulosus cathepsin l1 0.0068 0.1016 0.2626
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0035 0.009
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0008 0.0035 0.009
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0035 0.009
Brugia malayi Dopamine receptor protein 2 0.0044 0.0617 0.1594
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0056 0.0129
Brugia malayi voltage-dependent calcium channel 0.0008 0.0035 0.009
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0035 0.009
Schistosoma mansoni hypothetical protein 0.0011 0.0086 0.0222
Echinococcus granulosus cathepsin l cysteine peptidase 0.0102 0.1566 0.4048
Loa Loa (eye worm) hypothetical protein 0.0009 0.0056 0.0144
Schistosoma mansoni hypothetical protein 0.0011 0.0086 0.0222
Echinococcus multilocularis neuropeptide receptor A26 0.0146 0.2288 0.5912
Onchocerca volvulus 0.0102 0.1566 1
Schistosoma mansoni septate junction protein 0.0011 0.0086 0.0222
Onchocerca volvulus Cathepsin L homolog 0.0102 0.1566 1
Schistosoma mansoni peroxidasin 0.0016 0.0159 0.0411
Trypanosoma cruzi glyoxalase II 0.0009 0.0047 0.0194
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Brugia malayi metallo-beta-lactamase superfamily protein 0.0009 0.0047 0.0122
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.0009 0.0047 0.0118
Schistosoma mansoni notch 0.0011 0.0086 0.0222
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0015 0.0143 0.0369
Mycobacterium tuberculosis Conserved protein 0.0022 0.026 0.0563
Echinococcus granulosus semaphorin 5B 0.0014 0.0139 0.036
Brugia malayi Cathepsin L-like cysteine proteinase 0.0068 0.1016 0.2626
Brugia malayi EGF-like domain containing protein 0.0011 0.0086 0.0222
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0209 0.0541
Schistosoma mansoni cpg binding protein 0.0007 0.0012 0.0032
Plasmodium vivax hydroxyacyl glutathione hydrolase, putative 0.0009 0.0047 0.0097
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0009 0.0056 0.0239
Brugia malayi Fibulin-1 precursor 0.0016 0.0166 0.043
Echinococcus granulosus TRP transient receptor potential channel 0.0008 0.0035 0.009
Schistosoma mansoni cathepsin F (C01 family) 0.0068 0.1016 0.2626
Echinococcus multilocularis ETHE1 protein 0.0009 0.0047 0.0122
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0035 0.009
Brugia malayi hypothetical protein 0.0044 0.0617 0.1594
Schistosoma mansoni hypothetical protein 0.0044 0.0617 0.1594
Brugia malayi Muscle positioning protein 4 0.0011 0.0086 0.0222
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0185 0.2929 0.7569
Leishmania major cathepsin L-like protease 0.0102 0.1566 0.8097
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0047 0.0106
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0011 0.0086 0.0222
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.1566 0.4038
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0019 0.0209 0.0526
Toxoplasma gondii metallo-beta-lactamase domain-containing protein 0.0009 0.0047 0.0038
Loa Loa (eye worm) animal heme peroxidase 0.0016 0.0159 0.0411
Loa Loa (eye worm) hypothetical protein 0.0019 0.0209 0.0541
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.001 0.0071 0.0184
Leishmania major cathepsin L-like protease 0.0102 0.1566 0.8097
Echinococcus granulosus protein jagged 1 0.0011 0.0086 0.0222
Giardia lamblia Cathepsin B precursor 0.0019 0.0209 0.0517
Plasmodium vivax serine-repeat antigen (SERA) 0.0019 0.0209 0.0517
Echinococcus multilocularis nervana 2 0.0044 0.0624 0.1613
Echinococcus multilocularis calcium activated potassium channel 0.0008 0.0035 0.009
Schistosoma mansoni neuropeptide f receptor 76f 0.0044 0.0617 0.1594
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0008 0.0035 0.0221
Echinococcus multilocularis cathepsin L 0.0052 0.0759 0.1962
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0035 0.009
Brugia malayi hypothetical protein 0.0044 0.0617 0.1594
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.026 0.1305
Echinococcus granulosus protein jagged 1 0.0011 0.0086 0.0222
Schistosoma mansoni 60S ribosomal protein L21 0.0008 0.0035 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0063 0.0931 0.2386
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Brugia malayi Probable exocyst complex component Sec5 0.0006 0.0006 0.0015
Echinococcus granulosus zinc phosphodiesterase 0.0009 0.0047 0.0122
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0095 0.1452 0.3753
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.001 0.0071 0.0184
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0007 0.0013 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Schistosoma mansoni hypothetical protein 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.024 0.3833 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0041 0.057 0.2923
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0102 0.1566 0.4048
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.0009 0.0047 0.0118
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0008 0.0035 0.0221
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Echinococcus multilocularis neurogenic locus notch protein 0.0011 0.0086 0.0222
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0242 0.387 1
Entamoeba histolytica cysteine protease, putative 0.0052 0.0759 0.1959
Loa Loa (eye worm) hypothetical protein 0.0022 0.026 0.0672
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Schistosoma mansoni semaphorin 5-related 0.0014 0.0139 0.036
Echinococcus multilocularis neuropeptides capa receptor 0.0044 0.0617 0.1594
Schistosoma mansoni hypothetical protein 0.0008 0.0035 0.009
Trichomonas vaginalis penicillin-binding protein, putative 0.0022 0.026 0.0658
Echinococcus multilocularis cysteine protease 0.0102 0.1566 0.4048
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0019 0.0209 0.0517
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0008 0.0035 0.009
Loa Loa (eye worm) jmjC domain-containing protein 0.0008 0.0038 0.0099
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0016 0.0166 0.043
Entamoeba histolytica cysteine protease, putative 0.0052 0.0759 0.1959
Onchocerca volvulus 0.0044 0.0617 0.3939
Echinococcus multilocularis potassium voltage gated channel protein 0.0008 0.0035 0.009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0007 0.0013 0.0033
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0102 0.1566 0.4033
Echinococcus granulosus biogenic amine 5HT receptor 0.0044 0.0617 0.1594
Echinococcus multilocularis PHD finger protein rhinoceros 0.0007 0.001 0.0025
Giardia lamblia Hydroxyacylglutathione hydrolase 0.0009 0.0047 0.0097
Plasmodium falciparum cysteine repeat modular protein 1 0.0021 0.0251 0.0624
Schistosoma mansoni growth hormone secretagogue receptor 0.0044 0.0617 0.1594
Entamoeba histolytica cysteine protease, putative 0.0052 0.0759 0.1959
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0209 0.0541
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Loa Loa (eye worm) TK/ROR protein kinase 0.0023 0.0278 0.0719
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.1016 0.2614
Echinococcus multilocularis G protein coupled receptor 139 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0027 0.0348 0.0898
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0019 0.0209 0.0517
Trichomonas vaginalis beta lactamase domain, putative 0.0009 0.0047 0.0106
Brugia malayi Animal haem peroxidase family protein 0.0016 0.0159 0.0411
Entamoeba histolytica tyrosin kinase, putative 0.0008 0.0034 0.0083
Trypanosoma cruzi cysteine peptidase, putative 0.0124 0.1928 1
Echinococcus multilocularis voltage dependent calcium channel 0.0185 0.2929 0.7569
Echinococcus granulosus tissue type plasminogen activator 0.0021 0.0251 0.0647
Plasmodium falciparum serine repeat antigen 4 0.0019 0.0209 0.0517
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0008 0.0035 0.009
Trypanosoma cruzi cruzipain precursor, putative 0.0124 0.1928 1
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0008 0.0035 0.009
Giardia lamblia Cathepsin B precursor 0.0019 0.0209 0.0517
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0008 0.0035 0.009
Onchocerca volvulus 0.0011 0.0086 0.0549
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Echinococcus granulosus g protein coupled receptor 0.0044 0.0617 0.1594
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0056 0.0129
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0044 0.0617 0.1594
Echinococcus granulosus calcium activated potassium channel 0.0008 0.0035 0.009
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0066 0.0978 0.2509
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.001 0.0071 0.0184
Brugia malayi hypothetical protein 0.0014 0.0139 0.036
Trypanosoma cruzi cysteine protease, putative 0.0052 0.0759 0.3909
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1928 1
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0063 0.0931 0.2405
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.0209 0.0541
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0009 0.0047 0.0122
Echinococcus granulosus two pore calcium channel protein 2 0.0008 0.0035 0.009
Brugia malayi putative neuropeptide receptor NPR1 0.0044 0.0617 0.1594
Plasmodium vivax P-type ATPase4, putative 0.001 0.0071 0.016
Schistosoma mansoni amine GPCR 0.0044 0.0617 0.1594
Echinococcus granulosus voltage gated potassium channel 0.0008 0.0035 0.009
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0008 0.0035 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0047 0.0106
Mycobacterium tuberculosis Probable hydrolase 0.0022 0.026 0.0563
Loa Loa (eye worm) sema domain-containing protein 0.0014 0.0139 0.036
Echinococcus granulosus two pore calcium channel protein 1 0.0008 0.0035 0.009
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0617 0.1594
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0063 0.0931 0.4802
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.0617 0.1594
Schistosoma mansoni notch 0.0011 0.0086 0.0222
Toxoplasma gondii cathepsin CPC1 0.0019 0.0209 0.02
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0759 0.195
Trypanosoma cruzi cysteine proteinase, putative 0.0052 0.0759 0.3909
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0007 0.001 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.0617 0.1594
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0008 0.0035 0.009
Loa Loa (eye worm) hypothetical protein 0.0011 0.0086 0.0222
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0008 0.0035 0.009
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0102 0.1566 0.4033
Schistosoma mansoni notch 0.0011 0.0086 0.0222
Brugia malayi hypothetical protein 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0008 0.0035 0.009
Echinococcus granulosus hypothetical protein 0.0044 0.0617 0.1594
Schistosoma mansoni cpg binding protein 0.0006 0.0006 0.0016
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0008 0.0035 0.009
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0185 0.2929 0.7569
Trichomonas vaginalis set domain proteins, putative 0.0053 0.0765 0.1964
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0377 0.6069 0.6051
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0056 0.0129
Entamoeba histolytica cysteine protease, putative 0.0052 0.0759 0.1959
Brugia malayi sulfakinin receptor protein 0.0044 0.0617 0.1594
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0009 0.0056 0.014
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0251 0.1255
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0066 0.0978 0.097
Leishmania major cysteine peptidase A (CPA) 0.0102 0.1566 0.8097
Schistosoma mansoni hypothetical protein 0.0006 0.0006 0.0015
Trypanosoma cruzi cysteine peptidase, putative 0.0102 0.1566 0.8116
Plasmodium vivax vivapain-3 0.0052 0.0759 0.1942
Brugia malayi EGF-like domain containing protein 0.0011 0.0086 0.0222
Loa Loa (eye worm) hypothetical protein 0.0016 0.0159 0.0411
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.1566 0.4038
Schistosoma mansoni hypothetical protein 0.0009 0.0047 0.0122
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0009 0.0056 0.0239
Loa Loa (eye worm) hypothetical protein 0.0017 0.0178 0.0461
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0063 0.0931 0.4802
Trypanosoma brucei glyoxalase II 0.0009 0.0047 0.0194
Brugia malayi PHD-finger family protein 0.0007 0.001 0.0025
Giardia lamblia Hydroxyacylglutathione hydrolase 0.0009 0.0047 0.0097
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1594
Loa Loa (eye worm) hypothetical protein 0.0006 0.0006 0.0015
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0185 0.2929 0.7569
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1566 0.4038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0209 0.0526
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0023 0.0286 0.0739
Schistosoma mansoni biogenic amine receptor 0.0044 0.0617 0.1594
Onchocerca volvulus 0.0019 0.0209 0.1335
Echinococcus multilocularis short transient receptor potential channel 6 0.0008 0.0035 0.009
Plasmodium vivax basic transcription factor 3b, putative 0.0008 0.0029 0.005
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0044 0.0617 0.1594
Onchocerca volvulus 0.0044 0.0617 0.3939
Echinococcus granulosus biogenic amine 5HT receptor 0.0044 0.0617 0.1594
Onchocerca volvulus Peroxidasin homolog 0.0016 0.0159 0.1016
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0044 0.0617 0.1594
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.0617 0.1594

Activities

Activity type Activity value Assay description Source Reference
Cp (functional) = 4.6 uM Anticoagulant activity in human plasma assessed as concentration required to double prothrombin time ChEMBL. 17227710
Ki (binding) = 0.45 nM Binding affinity to human factor 10a after 10 mins ChEMBL. 17227710
Ki (binding) = 160 nM Binding affinity to human thrombin after 10 mins ChEMBL. 17227710
Ki app (binding) = 0.45 nM Binding affinity to human factor 10a after 10 mins ChEMBL. 17227710
Ki app (binding) = 160 nM Binding affinity to human thrombin after 10 mins ChEMBL. 17227710
Ki app (binding) > 5000 nM Binding affinity to bovine trypsin after 10 mins ChEMBL. 17227710

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.