Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0302 | 0.8749 | 0.9905 |
Schistosoma mansoni | hypothetical protein | 0.0343 | 1 | 1 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0195 | 0.5449 | 0.5422 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0289 | 0.8359 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0199 | 0.5581 | 0.5554 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0049 | 0.0947 | 0.1072 |
Echinococcus granulosus | hexokinase | 0.024 | 0.6835 | 0.6816 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0108 | 0.2782 | 0.2738 |
Schistosoma mansoni | hypothetical protein | 0.0299 | 0.8667 | 0.8658 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0541 | 0.0469 |
Brugia malayi | Muscleblind-like protein | 0.0302 | 0.8749 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0541 | 0.0613 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0301 | 0.8735 | 0.9983 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0154 | 0.0094 |
Brugia malayi | hypothetical protein | 0.0051 | 0.1013 | 0.0969 |
Schistosoma mansoni | hypothetical protein | 0.0305 | 0.8834 | 0.8827 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.2782 | 0.3201 |
Loa Loa (eye worm) | glutaminase 2 | 0.0271 | 0.7783 | 0.881 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.821 | 0.9817 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0322 | 0.0264 |
Loa Loa (eye worm) | intermediate filament protein | 0.0054 | 0.1095 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.021 | 0.0238 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0541 | 0.0484 |
Trypanosoma brucei | hexokinase | 0.024 | 0.6835 | 0.8288 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.821 | 0.9817 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0077 | 0.1828 | 0.2164 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0077 | 0.1828 | 0.1778 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0903 | 0.1022 |
Schistosoma mansoni | lamin | 0.0054 | 0.1095 | 0.1041 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1095 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0302 | 0.8749 | 0.9905 |
Echinococcus granulosus | hexokinase | 0.024 | 0.6835 | 0.6816 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0056 | 0.1156 | 0.1102 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0541 | 0.0469 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0026 | 0.024 | 0.0181 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0029 | 0.0328 | 0.0169 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0049 | 0.0947 | 0.0892 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0284 | 0.821 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0154 | 0.0094 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.821 | 0.9817 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 0.3115 | 0.3526 |
Trichomonas vaginalis | glutaminase, putative | 0.0271 | 0.7783 | 0.9297 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0049 | 0.0947 | 0.0892 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0199 | 0.5581 | 0.5554 |
Schistosoma mansoni | hexokinase | 0.024 | 0.6835 | 0.6816 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0141 | 0.3799 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0047 | 0.0903 | 0.0848 |
Onchocerca volvulus | 0.024 | 0.6835 | 0.8208 | |
Echinococcus granulosus | muscleblind protein | 0.0302 | 0.8749 | 0.8742 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.1439 | 0.1387 |
Trypanosoma brucei | unspecified product | 0.0077 | 0.1828 | 0.2049 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0322 | 0.021 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0651 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0788 | 0.0892 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0174 | 0.4795 | 0.5428 |
Echinococcus multilocularis | hexokinase | 0.024 | 0.6835 | 0.6816 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0903 | 0.0848 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0305 | 0.8834 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0302 | 0.8749 | 0.8742 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0056 | 0.1156 | 0.1102 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0056 | 0.1156 | 0.1102 |
Leishmania major | DNA polymerase eta, putative | 0.0128 | 0.3388 | 0.4013 |
Entamoeba histolytica | hexokinase 1 | 0.024 | 0.6835 | 0.8142 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0049 | 0.0947 | 0.0892 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.1441 | 0.1389 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2049 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0289 | 0.8359 | 1 |
Echinococcus granulosus | hexokinase type 2 | 0.024 | 0.6835 | 0.6816 |
Onchocerca volvulus | 0.0054 | 0.1095 | 0.0722 | |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.3388 | 0.3836 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0047 | 0.0903 | 0.1022 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0077 | 0.1828 | 0.192 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1013 | 0.1147 |
Onchocerca volvulus | 0.024 | 0.6835 | 0.8208 | |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0284 | 0.821 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0077 | 0.1828 | 0.2173 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0289 | 0.8359 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.0077 | 0.1828 | 0.1778 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0903 | 0.0848 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0541 | 0.0471 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0284 | 0.821 | 0.937 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0289 | 0.8359 | 1 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0024 | 0.0183 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0947 | 0.1072 |
Schistosoma mansoni | kinase | 0.0145 | 0.3898 | 0.3861 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0541 | 0.0484 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0284 | 0.821 | 1 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0229 | 0.0053 |
Leishmania major | hexokinase, putative | 0.024 | 0.6835 | 0.8293 |
Loa Loa (eye worm) | hexokinase | 0.0074 | 0.173 | 0.1959 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0322 | 0.021 |
Onchocerca volvulus | 0.024 | 0.6835 | 0.8208 | |
Brugia malayi | Hexokinase family protein | 0.0074 | 0.173 | 0.1806 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0024 | 0.0183 | 0.0033 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.1441 | 0.1468 |
Echinococcus multilocularis | geminin | 0.0343 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.1441 | 0.1631 |
Schistosoma mansoni | intermediate filament proteins | 0.0054 | 0.1095 | 0.1041 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0284 | 0.821 | 0.9293 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.2597 | 0.2552 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0228 | 0.646 | 1 |
Toxoplasma gondii | hexokinase | 0.024 | 0.6835 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0541 | 0.0446 |
Echinococcus multilocularis | dna polymerase eta | 0.0128 | 0.3388 | 0.3348 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0077 | 0.1828 | 0.2069 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.2782 | 0.3201 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0094 | 0.0034 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0026 | 0.024 | 0.0181 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0541 | 0.0469 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0077 | 0.1828 | 0.1778 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0284 | 0.821 | 0.8199 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0183 | 0.0033 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0056 | 0.1156 | 0.1102 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0322 | 0.0264 |
Echinococcus granulosus | GPCR family 2 | 0.0047 | 0.0903 | 0.0848 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0077 | 0.1828 | 0.2173 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.024 | 0.0272 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0284 | 0.821 | 0.8199 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0154 | 0.0094 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.2782 | 0.3201 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0195 | 0.5449 | 0.5422 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0541 | 0.0613 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0284 | 0.821 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0051 | 0.1013 | 0.1064 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0049 | 0.0947 | 0.0892 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0541 | 0.0613 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0077 | 0.1828 | 0.2049 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0075 | 0.1744 | 0.2346 |
Schistosoma mansoni | DNA polymerase eta | 0.0128 | 0.3388 | 0.3348 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0077 | 0.1828 | 0.2038 |
Echinococcus multilocularis | GPCR, family 2 | 0.0047 | 0.0903 | 0.0848 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0094 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.2597 | 0.294 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0302 | 0.8749 | 0.8742 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1793 | 0.203 |
Plasmodium falciparum | hexokinase | 0.024 | 0.6835 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0541 | 0.0478 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0054 | 0.1095 | 0.124 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0541 | 0.0478 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0541 | 0.0613 |
Trypanosoma brucei | polo-like protein kinase | 0.0284 | 0.821 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0322 | 0.0365 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0056 | 0.1156 | 0.1135 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0541 | 0.0613 |
Onchocerca volvulus | Hexokinase homolog | 0.015 | 0.408 | 0.4615 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0141 | 0.3799 | 0.4758 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0541 | 0.0469 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0541 | 0.0471 |
Echinococcus granulosus | dna polymerase eta | 0.0128 | 0.3388 | 0.3348 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4485 | 0.5077 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0176 | 0.4877 | 0.5479 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0077 | 0.1828 | 0.2038 |
Loa Loa (eye worm) | hexokinase type II | 0.024 | 0.6835 | 0.7738 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0541 | 0.0471 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0047 | 0.0903 | 0.084 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0289 | 0.8359 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0541 | 0.0484 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2075 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0541 | 0.0613 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0289 | 0.8359 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0077 | 0.1808 | 0.1897 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0284 | 0.821 | 0.9817 |
Brugia malayi | Hexokinase family protein | 0.024 | 0.6835 | 0.7765 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.1013 | 0.1064 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2075 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.0947 | 0.0892 |
Schistosoma mansoni | hypothetical protein | 0.0108 | 0.2782 | 0.2738 |
Brugia malayi | hypothetical protein | 0.0108 | 0.2782 | 0.3034 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0541 | 0.0613 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0541 | 0.0418 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.821 | 0.9817 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0653 | 0.0739 |
Loa Loa (eye worm) | hexokinase | 0.024 | 0.6835 | 0.7738 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0183 | 0.0207 |
Leishmania major | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2075 |
Loa Loa (eye worm) | glutaminase | 0.0271 | 0.7783 | 0.881 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0541 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0728 | 0.0824 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0051 | 0.1013 | 0.1248 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.1326 | 0.1273 |
Brugia malayi | hexokinase type II | 0.0076 | 0.1793 | 0.188 |
Brugia malayi | glutaminase DH11.1 | 0.0271 | 0.7783 | 0.8871 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2049 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0077 | 0.1828 | 0.1778 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0171 | 0.4718 | 0.6817 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2075 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.1013 | 0.1248 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0049 | 0.0947 | 0.053 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0077 | 0.1828 | 0.2038 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0075 | 0.1744 | 0.1971 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0289 | 0.8359 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0289 | 0.8359 | 1 |
Trypanosoma brucei | hexokinase | 0.024 | 0.6835 | 0.8288 |
Brugia malayi | hexokinase | 0.024 | 0.6835 | 0.7765 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.1441 | 0.1389 |
Loa Loa (eye worm) | hexokinase | 0.024 | 0.6835 | 0.7738 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.1441 | 0.1468 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0541 | 0.0471 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.0947 | 0.0892 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0541 | 0.0469 |
Trypanosoma cruzi | hexokinase, putative | 0.024 | 0.6835 | 0.8293 |
Schistosoma mansoni | lamin | 0.0054 | 0.1095 | 0.1041 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0047 | 0.0903 | 0.084 |
Echinococcus multilocularis | hexokinase | 0.024 | 0.6835 | 0.6816 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.021 | 0.0238 |
Echinococcus granulosus | dna polymerase kappa | 0.0077 | 0.1828 | 0.1778 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.1673 | 0.1894 |
Echinococcus granulosus | snurportin 1 | 0.0305 | 0.8834 | 0.8827 |
Echinococcus multilocularis | snurportin 1 | 0.0305 | 0.8834 | 0.8827 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0051 | 0.1013 | 0.1034 |
Brugia malayi | Hexokinase family protein | 0.015 | 0.408 | 0.455 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0541 | 0.0471 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0541 | 0.0539 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0102 | 0.2597 | 0.2818 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0128 | 0.3388 | 0.4013 |
Loa Loa (eye worm) | MBCTL1 | 0.0056 | 0.1156 | 0.1308 |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.1441 | 0.1389 |
Echinococcus granulosus | intermediate filament protein | 0.0054 | 0.1095 | 0.1041 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0147 | 0.0087 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0147 | 0.0087 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0077 | 0.1828 | 0.1778 |
Echinococcus multilocularis | lamin | 0.0054 | 0.1095 | 0.1041 |
Trypanosoma brucei | unspecified product | 0.0053 | 0.1087 | 0.1127 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0322 | 0.0163 |
Echinococcus granulosus | lamin | 0.0054 | 0.1095 | 0.1041 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0903 | 0.0848 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.2782 | 0.3201 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0108 | 0.2782 | 0.2738 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0541 | 0.0418 |
Onchocerca volvulus | 0.0054 | 0.1095 | 0.0722 | |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0289 | 0.8359 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0541 | 0.0418 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0077 | 0.1828 | 0.2049 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0576 | 0.0519 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0077 | 0.1828 | 0.2049 |
Echinococcus multilocularis | hexokinase | 0.024 | 0.6835 | 0.6816 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0128 | 0.3388 | 0.3993 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0541 | 0.0418 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0141 | 0.3783 | 0.4421 |
Giardia lamblia | Kinase, PLK | 0.0284 | 0.821 | 0.9817 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0053 | 0.1087 | 0.1127 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0541 | 0.0478 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0576 | 0.0519 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0289 | 0.8359 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2049 |
Leishmania major | DNA polymerase kappa, putative | 0.0024 | 0.0183 | 0.0033 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.1441 | 0.1389 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.1013 | 0.1248 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.015 | 0.4057 | 0.4592 |
Echinococcus multilocularis | hexokinase type 2 | 0.024 | 0.6835 | 0.6816 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0141 | 0.3799 | 0.5503 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0183 | 0.0033 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0147 | 0.0087 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.1441 | 0.1631 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0541 | 0.0539 |
Echinococcus granulosus | lamin dm0 | 0.0054 | 0.1095 | 0.1041 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0053 | 0.1087 | 0.1127 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2049 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0322 | 0.0264 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0322 | 0.0174 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0289 | 0.8359 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1793 | 0.203 |
Mycobacterium ulcerans | glutaminase | 0.0271 | 0.7783 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0903 | 0.0848 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.1013 | 0.1064 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.821 | 0.9817 |
Giardia lamblia | DINP protein human, muc B family | 0.0077 | 0.1828 | 0.2011 |
Onchocerca volvulus | 0.0049 | 0.0947 | 0.053 | |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.1326 | 0.1273 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.8735 | 0.9889 |
Echinococcus multilocularis | lamin dm0 | 0.0054 | 0.1095 | 0.1041 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0049 | 0.0947 | 0.0892 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0541 | 0.0613 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0108 | 0.2782 | 0.2738 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2049 |
Echinococcus granulosus | traf and tnf receptor associated protein | 0.0176 | 0.4877 | 0.4846 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2049 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1156 | 0.1308 |
Entamoeba histolytica | hexokinase 2 | 0.024 | 0.6835 | 0.8142 |
Trypanosoma cruzi | hexokinase, putative | 0.024 | 0.6835 | 0.8293 |
Schistosoma mansoni | glutaminase | 0.0271 | 0.7783 | 0.7769 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0051 | 0.1013 | 0.1248 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0289 | 0.8359 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.015 | 0.4057 | 0.4522 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0056 | 0.1156 | 0.1102 |
Brugia malayi | intermediate filament protein | 0.0054 | 0.1095 | 0.1065 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0047 | 0.0903 | 0.0848 |
Loa Loa (eye worm) | hexokinase | 0.015 | 0.408 | 0.4619 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0029 | 0.0328 | 0.0371 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0322 | 0.0174 |
Plasmodium vivax | hexokinase, putative | 0.024 | 0.6835 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0284 | 0.821 | 0.8199 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.0322 | 0.021 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0128 | 0.3388 | 0.3742 |
Echinococcus multilocularis | traf and tnf receptor associated protein | 0.0176 | 0.4877 | 0.4846 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0457 | 0.0319 |
Leishmania major | DNA damage repair protein, putative | 0.0024 | 0.0183 | 0.0033 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0054 | 0.1095 | 0.1065 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.1065 | 0.1205 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 0.3115 | 0.3526 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2075 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0541 | 0.0469 |
Brugia malayi | RNA binding protein | 0.0065 | 0.1441 | 0.1468 |
Echinococcus multilocularis | musashi | 0.0054 | 0.1095 | 0.1041 |
Leishmania major | DNA polymerase eta, putative | 0.0075 | 0.1744 | 0.1971 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.1441 | 0.1631 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.1441 | 0.1389 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0024 | 0.0183 | 0.0033 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.0947 | 0.0892 |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.3115 | 0.3423 |
Onchocerca volvulus | 0.015 | 0.408 | 0.4615 | |
Trypanosoma brucei | unspecified product | 0.0053 | 0.1087 | 0.1127 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0141 | 0.3783 | 0.4421 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0053 | 0.1087 | 0.1127 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0077 | 0.1828 | 0.2049 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.1441 | 0.1389 |
Echinococcus granulosus | hexokinase | 0.024 | 0.6835 | 0.6816 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.1944 | 0.2056 |
Schistosoma mansoni | hypothetical protein | 0.0343 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0077 | 0.1828 | 0.2075 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.0947 | 0.0892 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.821 | 0.9817 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0284 | 0.821 | 0.9817 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0077 | 0.1828 | 0.2164 |
Trypanosoma brucei | hexokinase, putative | 0.024 | 0.6835 | 0.8288 |
Leishmania major | hexokinase, putative | 0.024 | 0.6835 | 0.8293 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.1441 | 0.1389 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 8.32 uM | Nitric oxide radical scavenging activity in PC12 cells by survival assay | ChEMBL. | 17306423 |
EC50 (functional) | = 29.71 uM | Hydroxyl radical scavenging activity in PC12 cell by survival assay | ChEMBL. | 17306423 |
EC50 (functional) | = 30.4 uM | Hydrogen peroxide radical scavenging activity in PC12 cell by survival assay | ChEMBL. | 17306423 |
Log EC50 (functional) | = 4.52 | Hydrogen peroxide radical scavenging activity in PC12 cell by survival assay | ChEMBL. | 17306423 |
Log EC50 (functional) | = 4.53 | Hydroxyl radical scavenging activity in PC12 cell by survival assay | ChEMBL. | 17306423 |
Log EC50 (functional) | = 5.08 | Nitric oxide radical scavenging activity in PC12 cells by survival assay | ChEMBL. | 17306423 |
log K (ADMET) | = 0.905 | Retention time, log K of the compound | ChEMBL. | 17306423 |
LogP | = 1.146 | Partition coefficient, log P of the compound | ChEMBL. | 17306423 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.