Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | zinc finger protein | 0.0281 | 0.3529 | 0.3495 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.0152 | 0.0109 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0281 | 0.3529 | 0.3495 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0722 | 0.953 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0024 | 0.0137 | 0.0137 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3529 | 0.4476 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0281 | 0.3529 | 0.3495 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.0152 | 0.0109 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0596 | 0.7689 | 0.7689 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0596 | 0.7689 | 0.9752 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0722 | 0.953 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0054 | 0.0532 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3529 | 0.4476 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0596 | 0.7689 | 0.7689 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0771 | 1 | 1 |
Brugia malayi | tailless protein | 0.0281 | 0.3529 | 0.4462 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0152 | 0.1414 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0596 | 0.7689 | 0.7689 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0596 | 0.7689 | 0.7676 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0281 | 0.3529 | 0.4462 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0596 | 0.7689 | 0.9752 |
Loa Loa (eye worm) | hypothetical protein | 0.0315 | 0.3974 | 0.5041 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3529 | 0.4476 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.002 | 0.0026 |
Echinococcus multilocularis | lamin | 0.0029 | 0.0199 | 0.0199 |
Echinococcus granulosus | lamin | 0.0029 | 0.0199 | 0.0199 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0082 | 0.003 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0281 | 0.3529 | 0.4552 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0596 | 0.7689 | 0.7689 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0053 | 0.0067 |
Leishmania major | hypothetical protein, conserved | 0.0054 | 0.0532 | 0.6834 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.0199 | 0.0252 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0722 | 0.953 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0054 | 0.0528 | 0.6779 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0152 | 0.0109 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0071 | 0.0754 | 0.0754 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3529 | 0.4476 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0069 | 0.0722 | 0.955 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0082 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0596 | 0.7689 | 0.7689 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0152 | 0.1414 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0596 | 0.7689 | 0.7676 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0152 | 0.0168 |
Schistosoma mansoni | nuclear receptor | 0.0281 | 0.3529 | 0.3495 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.0152 | 0.0109 |
Schistosoma mansoni | nuclear receptor | 0.0281 | 0.3529 | 0.3495 |
Brugia malayi | nuclear hormone receptor | 0.0596 | 0.7689 | 0.9751 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0596 | 0.7689 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0596 | 0.7689 | 0.7689 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.0152 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0281 | 0.3529 | 0.3529 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0278 | 0.0327 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0596 | 0.7689 | 0.9751 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0532 | 0.0675 |
Brugia malayi | steroid hormone receptor | 0.0596 | 0.7689 | 0.9751 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0152 | 0.1414 |
Echinococcus multilocularis | musashi | 0.0029 | 0.0199 | 0.0199 |
Echinococcus multilocularis | cysteine protease | 0.0018 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3529 | 0.4476 |
Brugia malayi | ecdysone receptor | 0.0281 | 0.3529 | 0.4462 |
Loa Loa (eye worm) | hypothetical protein | 0.0315 | 0.3974 | 0.5041 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0054 | 0.0532 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0281 | 0.3529 | 0.3495 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0596 | 0.7689 | 0.7689 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0152 | 0.0109 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0082 | 0.0419 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.0053 | 0.0042 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0596 | 0.7689 | 0.9751 |
Brugia malayi | conserved hypotetical protein | 0.0281 | 0.3529 | 0.4462 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0018 | 0.0053 | 0.0053 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0281 | 0.3529 | 0.4552 |
Loa Loa (eye worm) | hypothetical protein | 0.0596 | 0.7689 | 0.9752 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0722 | 0.953 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0067 | 0.0085 |
Onchocerca volvulus | 0.0026 | 0.0152 | 0.013 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0069 | 0.0722 | 0.955 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0281 | 0.3529 | 0.3529 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0596 | 0.7689 | 1 |
Onchocerca volvulus | 0.0281 | 0.3529 | 0.4552 | |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0071 | 0.0754 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.0199 | 0.0199 |
Onchocerca volvulus | 0.0029 | 0.0199 | 0.0191 | |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.0199 | 0.0199 |
Brugia malayi | hypothetical protein | 0.0054 | 0.0532 | 0.0651 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.0199 | 0.0227 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0596 | 0.7689 | 0.9751 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0067 | 0.0085 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.0082 | 0.5 |
Brugia malayi | hypothetical protein | 0.0281 | 0.3529 | 0.4462 |
Echinococcus multilocularis | muscleblind protein | 0.0161 | 0.194 | 0.194 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0596 | 0.7689 | 0.7689 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3529 | 0.4476 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0082 | 0.0613 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0281 | 0.3529 | 0.3529 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.0053 | 0.0042 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0281 | 0.3529 | 0.3529 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.0199 | 0.0252 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0071 | 0.0754 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0722 | 0.953 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0019 | 0.0067 | 0.0288 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0596 | 0.7689 | 0.9751 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0152 | 0.0168 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0018 | 0.0053 | 0.0053 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0082 | 0.2958 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0199 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0596 | 0.7689 | 0.9752 |
Brugia malayi | hypothetical protein | 0.0315 | 0.3974 | 0.5028 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0082 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0067 | 0.0085 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0281 | 0.3529 | 0.3529 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3529 | 0.4476 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0041 | 0.0358 | 0.0358 |
Loa Loa (eye worm) | glutaminase 2 | 0.0611 | 0.7884 | 1 |
Schistosoma mansoni | glutaminase | 0.0611 | 0.7884 | 0.7873 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.0152 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0281 | 0.3529 | 0.3495 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0281 | 0.3529 | 0.4462 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0315 | 0.3974 | 0.3942 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0071 | 0.0754 | 0.0956 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0152 | 0.0193 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0082 | 0.0419 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0152 | 0.0168 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0054 | 0.0532 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0722 | 0.953 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0596 | 0.7689 | 0.7689 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.0722 | 0.955 |
Loa Loa (eye worm) | hypothetical protein | 0.0596 | 0.7689 | 0.9752 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0596 | 0.7689 | 0.7689 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0596 | 0.7689 | 0.9752 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0596 | 0.7689 | 0.7689 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.0722 | 0.955 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.0152 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0161 | 0.194 | 0.2441 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0722 | 0.953 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0596 | 0.7689 | 0.9752 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.0152 | 0.0109 |
Schistosoma mansoni | nuclear hormone receptor | 0.0281 | 0.3529 | 0.3495 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0137 | 0.0084 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0281 | 0.3529 | 0.3529 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3529 | 0.4476 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0281 | 0.3529 | 0.4462 |
Schistosoma mansoni | nuclear hormone receptor | 0.0596 | 0.7689 | 0.7676 |
Loa Loa (eye worm) | hypothetical protein | 0.0596 | 0.7689 | 0.9752 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0067 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0596 | 0.7689 | 0.7676 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0018 | 0.0053 | 0.0067 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0018 | 0.0053 | 0.0053 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0596 | 0.7689 | 0.7676 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0082 | 0.0037 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0596 | 0.7689 | 0.7689 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0071 | 0.0754 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0161 | 0.194 | 0.194 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0281 | 0.3529 | 0.3529 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.0053 | 0.0042 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0281 | 0.3529 | 0.3529 |
Loa Loa (eye worm) | cysteine protease | 0.0018 | 0.0053 | 0.0067 |
Loa Loa (eye worm) | fibroinase | 0.0018 | 0.0053 | 0.0067 |
Brugia malayi | nuclear receptor RXR | 0.0315 | 0.3974 | 0.5028 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0315 | 0.3974 | 0.3942 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3529 | 0.4476 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0082 | 0.0082 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0596 | 0.7689 | 0.9751 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0019 | 0.0067 | 0.0288 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0071 | 0.0754 | 0.0754 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0067 | 0.139 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0596 | 0.7689 | 0.9752 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0315 | 0.3974 | 0.3974 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0082 | 0.003 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0281 | 0.3529 | 0.4462 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0018 | 0.0053 | 0.0067 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0722 | 0.953 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3529 | 0.4476 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0281 | 0.3529 | 0.4462 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0082 | 0.0419 |
Loa Loa (eye worm) | hypothetical protein | 0.0315 | 0.3974 | 0.5041 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0596 | 0.7689 | 0.9751 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.0053 | 0.0042 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0152 | 0.0109 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0024 | 0.0137 | 0.0137 |
Brugia malayi | hypothetical protein | 0.0281 | 0.3529 | 0.4462 |
Schistosoma mansoni | lamin | 0.0029 | 0.0199 | 0.0146 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0018 | 0.0053 | 0.0053 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.0053 | 0.0042 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0596 | 0.7689 | 0.7676 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.194 | 0.2461 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0054 | 0.0532 | 0.6834 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0281 | 0.3529 | 0.4476 |
Mycobacterium ulcerans | glutaminase | 0.0611 | 0.7884 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0722 | 0.953 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0018 | 0.0053 | 0.0042 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0596 | 0.7689 | 0.9751 |
Echinococcus multilocularis | cysteine protease | 0.0018 | 0.0053 | 0.0053 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0596 | 0.7689 | 0.9751 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0281 | 0.3529 | 0.4462 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0054 | 0.0532 | 0.6695 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0071 | 0.0754 | 1 |
Loa Loa (eye worm) | DR-78 | 0.0281 | 0.3529 | 0.4476 |
Schistosoma mansoni | thyroid hormone receptor | 0.0596 | 0.7689 | 0.7676 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0281 | 0.3529 | 0.3529 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0082 | 0.0079 |
Echinococcus granulosus | muscleblind protein | 0.0161 | 0.194 | 0.194 |
Brugia malayi | nuclear receptor NHR-88 | 0.0281 | 0.3529 | 0.4462 |
Brugia malayi | ecdysteroid receptor | 0.0596 | 0.7689 | 0.9751 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0722 | 0.953 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0596 | 0.7689 | 0.9751 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0281 | 0.3529 | 0.3529 |
Schistosoma mansoni | coup transcription factor | 0.0596 | 0.7689 | 0.7676 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0067 | 0.0085 |
Onchocerca volvulus | 0.0596 | 0.7689 | 1 | |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0315 | 0.3974 | 0.3974 |
Loa Loa (eye worm) | ctsf protein | 0.0018 | 0.0053 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3529 | 0.4476 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0722 | 0.953 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0069 | 0.0722 | 0.955 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0063 | 0.0644 | 0.8426 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0771 | 1 | 1 |
Schistosoma mansoni | lamin | 0.0029 | 0.0199 | 0.0146 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0596 | 0.7689 | 0.7689 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3529 | 0.4476 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.0152 | 0.0109 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0596 | 0.7689 | 0.7689 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0596 | 0.7689 | 0.9751 |
Brugia malayi | nuclear receptor NHR-88 | 0.0596 | 0.7689 | 0.9751 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0071 | 0.0754 | 0.0705 |
Brugia malayi | nuclear receptor NHR-67 | 0.0281 | 0.3529 | 0.4462 |
Loa Loa (eye worm) | hypothetical protein | 0.0315 | 0.3974 | 0.5041 |
Schistosoma mansoni | intermediate filament proteins | 0.0029 | 0.0199 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 0.3529 | 0.4476 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0082 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.194 | 0.2461 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.0152 | 0.1414 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0082 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0067 | 0.0085 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0596 | 0.7689 | 0.7676 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0596 | 0.7689 | 0.9751 |
Loa Loa (eye worm) | hypothetical protein | 0.0315 | 0.3974 | 0.5041 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0082 | 0.0105 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0315 | 0.3974 | 0.5028 |
Onchocerca volvulus | 0.0281 | 0.3529 | 0.4552 | |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0082 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0596 | 0.7689 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0596 | 0.7689 | 0.9752 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0069 | 0.0722 | 0.955 |
Brugia malayi | nuclear hormone receptor | 0.0281 | 0.3529 | 0.4462 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.0082 | 0.0419 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0281 | 0.3529 | 0.4476 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0596 | 0.7689 | 0.7689 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.0152 | 0.5 |
Brugia malayi | nuclear receptor RXR | 0.0281 | 0.3529 | 0.4462 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.0722 | 0.955 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0596 | 0.7689 | 0.9751 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0082 | 0.0613 |
Loa Loa (eye worm) | glutaminase | 0.0611 | 0.7884 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0596 | 0.7689 | 0.9752 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0054 | 0.0532 | 0.6834 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0041 | 0.0358 | 0.0358 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0596 | 0.7689 | 0.9752 |
Schistosoma mansoni | thyroid hormone receptor | 0.0596 | 0.7689 | 0.7676 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0071 | 0.0754 | 0.0933 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0071 | 0.0754 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0082 | 0.0613 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0192 | 0.0243 |
Onchocerca volvulus | 0.0029 | 0.0199 | 0.0191 | |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0596 | 0.7689 | 0.9751 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.0199 | 0.0227 |
Echinococcus granulosus | cathepsin l1 | 0.0018 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0596 | 0.7689 | 0.9752 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0281 | 0.3529 | 0.4476 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0152 | 0.0193 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0596 | 0.7689 | 0.7676 |
Brugia malayi | hypothetical protein | 0.0315 | 0.3974 | 0.5028 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0596 | 0.7689 | 0.7689 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0054 | 0.0532 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0018 | 0.0053 | 0.0053 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0596 | 0.7689 | 0.7689 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0152 | 0.1414 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0596 | 0.7689 | 0.7676 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0281 | 0.3529 | 0.3529 |
Loa Loa (eye worm) | hypothetical protein | 0.0596 | 0.7689 | 0.9752 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0596 | 0.7689 | 0.9751 |
Loa Loa (eye worm) | hypothetical protein | 0.0596 | 0.7689 | 0.9752 |
Brugia malayi | Cathepsin L-like precursor | 0.0018 | 0.0053 | 0.0042 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0018 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0596 | 0.7689 | 0.9752 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0596 | 0.7689 | 0.9751 |
Brugia malayi | glutaminase DH11.1 | 0.0611 | 0.7884 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0596 | 0.7689 | 0.9751 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0315 | 0.3974 | 0.5028 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0152 | 0.0193 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0315 | 0.3974 | 0.5041 |
Trichomonas vaginalis | glutaminase, putative | 0.0611 | 0.7884 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0281 | 0.3529 | 0.3529 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0596 | 0.7689 | 0.7689 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0596 | 0.7689 | 0.7676 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0152 | 0.1414 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 47.3 % | Antioxidant activity assessed as DPPH radical scavenging activity at 0.0156 g/L | ChEMBL. | 17166720 |
Activity (functional) | = 72.4 % | Antioxidant activity assessed as DPPH radical scavenging activity at 0.0312 g/L | ChEMBL. | 17166720 |
Activity (functional) | = 86.9 % | Antioxidant activity assessed as DPPH radical scavenging activity at 0.0625 g/L | ChEMBL. | 17166720 |
Activity (functional) | = 92.1 % | Antioxidant activity assessed as DPPH radical scavenging activity at 0.125 g/L | ChEMBL. | 17166720 |
Activity (functional) | = 94.7 % | Antioxidant activity assessed as DPPH radical scavenging activity at 0.250 g/L | ChEMBL. | 17166720 |
EC50 (functional) | = 0.00873 g/L | Antioxidant activity assessed as inhibition of lipid peroxidation after 2 hrs by beta carotene bleaching method | ChEMBL. | 17166720 |
EC50 (functional) | = 0.0173 g/L | Antioxidant activity assessed as DPPH radical scavenging activity | ChEMBL. | 17166720 |
EC50 (functional) | = 0.0189 g/L | Inhibition of AAPH-induced ram erythrocyte hemolysis | ChEMBL. | 17166720 |
EC50 (functional) | = 0.0227 g/L | Antioxidant activity assessed as reduction of ferric cyanide complex by reducing power assay | ChEMBL. | 17166720 |
Inhibition (functional) | = 47.8 % | Inhibition of AAPH-induced ram erythrocyte hemolysis at 0.0156 g/L | ChEMBL. | 17166720 |
Inhibition (functional) | = 58.3 % | Inhibition of AAPH-induced ram erythrocyte hemolysis at 0.0312 g/L | ChEMBL. | 17166720 |
Inhibition (functional) | = 61.2 % | Inhibition of AAPH-induced ram erythrocyte hemolysis at 0.0625 g/L | ChEMBL. | 17166720 |
Inhibition (functional) | = 62.1 % | Inhibition of AAPH-induced ram erythrocyte hemolysis at 0.125 g/L | ChEMBL. | 17166720 |
Inhibition (functional) | = 62.9 % | Inhibition of AAPH-induced ram erythrocyte hemolysis at 0.250 g/L | ChEMBL. | 17166720 |
Inhibition (functional) | = 89.3 % | Antioxidant activity assessed as inhibition of lipid peroxidation at 0.0156 g/L after 2 hrs by beta carotene bleaching method | ChEMBL. | 17166720 |
Inhibition (functional) | = 91.4 % | Antioxidant activity assessed as inhibition of lipid peroxidation at 0.0312 g/L after 2 hrs by beta carotene bleaching method | ChEMBL. | 17166720 |
Inhibition (functional) | = 100 % | Antioxidant activity assessed as inhibition of lipid peroxidation at 0.250 g/L after 2 hrs by beta carotene bleaching method | ChEMBL. | 17166720 |
Inhibition (functional) | = 100 % | Antioxidant activity assessed as inhibition of lipid peroxidation at 0.125 g/L after 2 hrs by beta carotene bleaching method | ChEMBL. | 17166720 |
Inhibition (functional) | = 100 % | Antioxidant activity assessed as inhibition of lipid peroxidation at 0.0625 g/L after 2 hrs by beta carotene bleaching method | ChEMBL. | 17166720 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.