TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 211.241 | Formula: C8H9N3O2S
H donors: 4 H acceptors: 2 LogP: 0.49 Rotable bonds: 3
Rule of 5 violations (Lipinski): 1
SMILES: NC(=S)N/N=C/c1ccc(cc1O)O
InChi: 1S/C8H9N3O2S/c9-8(14)11-10-4-5-1-2-6(12)3-7(5)13/h1-4,12-13H,(H3,9,11,14)/b10-4+
InChiKey: DZTQPWJXTVXKJK-ONNFQVAWSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0044	0.1067	0.1067
Leishmania major	GTP-binding protein, putative	0.0022	0.0313	0.1208
Trichomonas vaginalis	glutaminase, putative	0.0279	0.8835	1
Trypanosoma brucei	unspecified product	0.0013	0.0029	0.0113
Trypanosoma brucei	DNA polymerase kappa, putative	0.0013	0.0029	0.0113
Schistosoma mansoni	hypothetical protein	0.0015	0.0103	0.0103
Trypanosoma brucei	importin beta-1 subunit, putative	0.0029	0.0571	0.22
Mycobacterium ulcerans	glucose-6-phosphate 1-dehydrogenase	0.009	0.2594	0.2752
Trichomonas vaginalis	glucosamine-6-phosphate isomerase, putative	0.0099	0.2861	0.3238
Schistosoma mansoni	ran	0.0022	0.0313	0.0313
Onchocerca volvulus		0.0033	0.0684	0.0186
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0015	0.0103	0.0103
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0015	0.0103	0.0117
Schistosoma mansoni	DNA polymerase eta	0.0044	0.1053	0.1053
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0015	0.0103	0.0103
Chlamydia trachomatis	glucose-6-phosphate 1-dehydrogenase	0.009	0.2594	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0036	0.0778	0.088
Brugia malayi	ImpB/MucB/SamB family protein	0.0044	0.1053	0.1192
Echinococcus granulosus	importin subunit beta 1	0.0029	0.0571	0.0571
Trichomonas vaginalis	conserved hypothetical protein	0.0036	0.0778	0.088
Schistosoma mansoni	caspase-7 (C14 family)	0.003	0.0602	0.0602
Schistosoma mansoni	terminal deoxycytidyl transferase	0.0019	0.0224	0.0224
Echinococcus multilocularis	importin subunit beta 1	0.0029	0.0571	0.0571
Loa Loa (eye worm)	transcription factor SMAD2	0.0116	0.3434	0.3434
Trypanosoma brucei	GTP-binding nuclear protein rtb2, putative	0.0022	0.0313	0.1208
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0684	0.0684
Trichomonas vaginalis	glucosylceramidase, putative	0.0251	0.7898	0.894
Leishmania major	basic transcription factor 3a, putative	0.0036	0.0778	0.2999
Loa Loa (eye worm)	hypothetical protein	0.0239	0.751	0.751
Trypanosoma brucei	DNA polymerase eta, putative	0.0044	0.1053	0.4061
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Echinococcus multilocularis	Coagulation factor 5 8 type, C terminal	0.0071	0.1943	0.1943
Trypanosoma cruzi	DNA polymerase eta, putative	0.0044	0.1053	0.4061
Giardia lamblia	GTP-binding nuclear protein RAN/TC4	0.0022	0.0313	0.1096
Trypanosoma cruzi	glucose-6-phosphate 1-dehydrogenase, putative	0.003	0.0589	0.2273
Trichomonas vaginalis	glucosylceramidase, putative	0.0164	0.5044	0.5708
Trypanosoma cruzi	transcription factor btf3, putative	0.0036	0.0778	0.2999
Schistosoma mansoni	ubiquitin-like protein sumo/smt3-related	0.0053	0.1358	0.1358
Trichomonas vaginalis	glucosylceramidase, putative	0.0164	0.5044	0.5708
Trypanosoma brucei	small ubiquitin-related modifier	0.0053	0.1358	0.5237
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0692	0.0692
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0015	0.0103	0.0103
Echinococcus granulosus	GTP binding nuclear protein Ran	0.0022	0.0313	0.0313
Trichomonas vaginalis	glucosylceramidase, putative	0.0164	0.5044	0.5708
Brugia malayi	hypothetical protein	0.003	0.0602	0.0681
Toxoplasma gondii	glucose-6-phosphate 1-dehydrogenase	0.0099	0.2861	1
Schistosoma mansoni	glutaminase	0.0279	0.8835	0.8835
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0044	0.1067	0.1067
Schistosoma mansoni	glucose-6-phosphate 1-dehydrogenase	0.009	0.2594	0.2594
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Brugia malayi	Ubiquitin-like protein SMT3	0.0053	0.1358	0.1538
Plasmodium vivax	glucose-6-phosphate 1-dehydrogenase, putative	0.0099	0.2861	1
Leishmania major	DNA polymerase eta, putative	0.0031	0.062	0.2391
Trichomonas vaginalis	glucosylceramidase, putative	0.0173	0.5337	0.604
Brugia malayi	MH2 domain containing protein	0.0116	0.3434	0.3887
Plasmodium vivax	GTP-binding nuclear protein RAN/TC4, putative	0.0022	0.0313	0.1096
Echinococcus multilocularis	Small ubiquitin modifier 2	0.0053	0.1358	0.1358
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0022	0.0313	0.1208
Trypanosoma cruzi	small ubiquitin protein, putative	0.0053	0.1358	0.5237
Loa Loa (eye worm)	hypothetical protein	0.0048	0.1199	0.1199
Loa Loa (eye worm)	glutaminase	0.0279	0.8835	0.8835
Trypanosoma cruzi	importin beta-1 subunit, putative	0.0024	0.0386	0.149
Brugia malayi	ImpB/MucB/SamB family protein	0.0019	0.0224	0.0254
Entamoeba histolytica	hypothetical protein	0.0024	0.0386	0.2844
Echinococcus multilocularis	dna polymerase kappa	0.0019	0.0224	0.0224
Mycobacterium ulcerans	glutaminase	0.0279	0.8835	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Trypanosoma brucei	glucose-6-phosphate 1-dehydrogenase	0.009	0.2594	1
Brugia malayi	glucose-6-phosphate dehydrogenase	0.009	0.2594	0.2936
Plasmodium falciparum	small ubiquitin-related modifier	0.0053	0.1358	0.4748
Schistosoma mansoni	ran	0.0022	0.0313	0.0313
Trypanosoma brucei	DNA polymerase IV, putative	0.0019	0.0224	0.0865
Trypanosoma brucei	importin beta-1 subunit, putative	0.0029	0.0571	0.22
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0019	0.0224	0.0254
Trichomonas vaginalis	glucosylceramidase, putative	0.0251	0.7898	0.894
Trichomonas vaginalis	glucosamine-6-phosphate isomerase, putative	0.0099	0.2861	0.3238
Trichomonas vaginalis	ran, putative	0.0022	0.0313	0.0355
Trichomonas vaginalis	conserved hypothetical protein	0.0036	0.0778	0.088
Schistosoma mansoni	hypothetical protein	0.003	0.0602	0.0602
Echinococcus granulosus	Small ubiquitin modifier 2	0.0053	0.1358	0.1358
Echinococcus multilocularis	dedicator of cytokinesis protein	0.006	0.1572	0.1572
Trypanosoma cruzi	Glucose-6-phosphate dehydrogenase, putative	0.0029	0.0561	0.2162
Trichomonas vaginalis	glucosylceramidase, putative	0.0164	0.5044	0.5708
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.0019	0.0224	0.0224
Brugia malayi	beta-NAC-like protein	0.0036	0.0778	0.088
Toxoplasma gondii	small ubiquitin family modifier, putative	0.0053	0.1358	0.4748
Plasmodium vivax	basic transcription factor 3b, putative	0.0036	0.0778	0.2719
Brugia malayi	RNA, U transporter 1	0.0084	0.2368	0.268
Trypanosoma brucei	DNA polymerase IV, putative	0.0019	0.0224	0.0865
Brugia malayi	Cell death protein 3 precursor	0.003	0.0602	0.0681
Entamoeba histolytica	hypothetical protein	0.0033	0.0684	0.5038
Loa Loa (eye worm)	hypothetical protein	0.0044	0.1053	0.1053
Trichomonas vaginalis	6-phosphogluconolactonase, putative	0.0099	0.2861	0.3238
Leishmania major	glucose-6-phosphate 1-dehydrogenase, putative	0.009	0.2594	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0013	0.0029	0.0113
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0044	0.1067	0.1067
Leishmania major	importin beta-1 subunit, putative	0.0024	0.0386	0.149
Trichomonas vaginalis	conserved hypothetical protein	0.0053	0.1358	0.1538
Trichomonas vaginalis	glucosylceramidase, putative	0.0164	0.5044	0.5708
Mycobacterium tuberculosis	Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD)	0.0031	0.0636	1
Entamoeba histolytica	hypothetical protein	0.0036	0.0778	0.5726
Echinococcus granulosus	dna polymerase eta	0.0044	0.1053	0.1053
Trichomonas vaginalis	glucosylceramidase, putative	0.0251	0.7898	0.894
Brugia malayi	Importin beta-1 subunit	0.0029	0.0571	0.0646
Loa Loa (eye worm)	glucose-6-phosphate dehydrogenase	0.009	0.2594	0.2594
Echinococcus multilocularis	ubiquitin	0.0033	0.0684	0.0684
Brugia malayi	Latrophilin receptor protein 2	0.0015	0.0103	0.0117
Schistosoma mansoni	importin beta-1	0.0029	0.0571	0.0571
Giardia lamblia	DINP protein human, muc B family	0.0019	0.0224	0.0784
Trypanosoma cruzi	DNA polymerase eta, putative	0.0031	0.062	0.2391
Echinococcus granulosus	caspase 2	0.003	0.0602	0.0602
Echinococcus granulosus	Coagulation factor 5 8 type C terminal	0.0071	0.1943	0.1943
Echinococcus granulosus	ubiquitin	0.0033	0.0684	0.0684
Schistosoma mansoni	hypothetical protein	0.0314	1	1
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.1067	0.1067
Echinococcus multilocularis	transcription factor btf3	0.0036	0.0778	0.0778
Brugia malayi	hypothetical protein	0.0033	0.0684	0.0775
Echinococcus multilocularis	snurportin 1	0.0314	1	1
Leishmania major	DNA polymerase kappa, putative,DNA polymerase IV, putative	0.0019	0.0224	0.0865
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.0019	0.0224	0.0224
Loa Loa (eye worm)	hypothetical protein	0.003	0.0602	0.0602
Echinococcus granulosus	dna polymerase kappa	0.0019	0.0224	0.0224
Toxoplasma gondii	HEAT repeat-containing protein	0.0029	0.0571	0.1995
Toxoplasma gondii	glucose-6-phosphate 1-dehydrogenase	0.0059	0.1554	0.5432
Plasmodium falciparum	basic transcription factor 3b, putative	0.0036	0.0778	0.2719
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0225	0.7042	0.7042
Plasmodium falciparum	glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0.0099	0.2861	1
Echinococcus multilocularis	dna polymerase eta	0.0044	0.1053	0.1053
Brugia malayi	glutaminase DH11.1	0.0279	0.8835	1
Loa Loa (eye worm)	O-glycosyl hydrolase family 30 protein	0.0251	0.7898	0.7898
Echinococcus multilocularis	caspase 2	0.003	0.0602	0.0602
Trichomonas vaginalis	DNA polymerase eta, putative	0.0019	0.0224	0.0254
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0044	0.1067	0.1067
Brugia malayi	GTP-binding nuclear protein RAN/TC4	0.0022	0.0313	0.0355
Giardia lamblia	Sentrin	0.0053	0.1358	0.4748
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Schistosoma mansoni	hypothetical protein	0.0024	0.0391	0.0391
Echinococcus multilocularis	glucose 6 phosphate 1 dehydrogenase	0.009	0.2594	0.2594
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Loa Loa (eye worm)	ICD-1 protein	0.0036	0.0778	0.0778
Trichomonas vaginalis	glucosylceramidase, putative	0.0251	0.7898	0.894
Entamoeba histolytica	deoxycytidyl transferase, putative	0.0019	0.0224	0.1651
Trichomonas vaginalis	glucosylceramidase, putative	0.0164	0.5044	0.5708
Onchocerca volvulus	Glucosylceramidase homolog	0.0164	0.5044	1
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0571	0.0571
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0015	0.0103	0.0103
Entamoeba histolytica	Ran family GTPase	0.0022	0.0313	0.2307
Schistosoma mansoni	dock	0.0071	0.1943	0.1943
Trypanosoma brucei	unspecified product	0.0019	0.0224	0.0865
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0015	0.0103	0.0103
Echinococcus multilocularis	GPCR, family 2	0.0015	0.0103	0.0103
Echinococcus multilocularis	apoptotic protease activating factor 1	0.003	0.0602	0.0602
Schistosoma mansoni	hypothetical protein	0.0015	0.0103	0.0103
Brugia malayi	follicle stimulating hormone receptor	0.0225	0.7042	0.797
Trypanosoma cruzi	transcription factor btf3, putative	0.0036	0.0778	0.2999
Schistosoma mansoni	hypothetical protein	0.0015	0.0103	0.0103
Plasmodium vivax	importin-beta 2, putative	0.0029	0.0571	0.1995
Trypanosoma brucei	DNA polymerase IV, putative	0.0019	0.0224	0.0865
Trypanosoma brucei	transcription factor BTF3, putative	0.0036	0.0778	0.2999
Toxoplasma gondii	GTP-binding nuclear protein ran/tc4	0.0022	0.0313	0.1096
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.1067	0.1067
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Entamoeba histolytica	transcription factor BTF3, putative	0.0036	0.0778	0.5726
Entamoeba histolytica	ubiquitin like protein	0.0053	0.1358	1
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0314	1	1
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0044	0.1067	0.1067
Plasmodium falciparum	importin beta, putative	0.0029	0.0571	0.1995
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Trichomonas vaginalis	glucosylceramidase, putative	0.0173	0.5337	0.604
Toxoplasma gondii	NAC domain-containing protein	0.0036	0.0778	0.2719
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0048	0.1199	0.1357
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.1067	0.1067
Trichomonas vaginalis	ubiquitin, putative	0.0033	0.0684	0.0775
Loa Loa (eye worm)	hypothetical protein	0.003	0.0602	0.0602
Trichomonas vaginalis	importin beta-1, putative	0.0024	0.0386	0.0437
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0022	0.0313	0.1208
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Brugia malayi	photoreceptor-specific nuclear receptor	0.0239	0.751	0.85
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0048	0.1199	0.1199
Mycobacterium ulcerans	glucose-6-phosphate 1-dehydrogenase	0.0059	0.1554	0.1544
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.0019	0.0224	0.0224
Trypanosoma brucei	unspecified product	0.0013	0.0029	0.0113
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0103	0.0103
Trichomonas vaginalis	glucosylceramidase, putative	0.0251	0.7898	0.894
Brugia malayi	O-Glycosyl hydrolase family 30 protein	0.0251	0.7898	0.894
Echinococcus granulosus	GPCR family 2	0.0015	0.0103	0.0103
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Leishmania major	small ubiquitin protein, putative	0.0053	0.1358	0.5237
Loa Loa (eye worm)	SMO-1 protein	0.0053	0.1358	0.1358
Schistosoma mansoni	transcription factor btf3	0.0036	0.0778	0.0778
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0044	0.1067	0.1207
Loa Loa (eye worm)	MH2 domain-containing protein	0.0116	0.3434	0.3434
Loa Loa (eye worm)	GTP-binding nuclear protein RAN/TC4	0.0022	0.0313	0.0313
Toxoplasma gondii	ImpB/MucB/SamB family protein	0.0031	0.062	0.2168
Leishmania major	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Echinococcus granulosus	glucose 6 phosphate 1 dehydrogenase	0.009	0.2594	0.2594
Trypanosoma cruzi	small ubiquitin protein, putative	0.0053	0.1358	0.5237
Trypanosoma cruzi	glucose-6-phosphate 1-dehydrogenase, putative	0.009	0.2594	1
Leishmania major	DNA polymerase eta, putative	0.0044	0.1053	0.4061
Trichomonas vaginalis	glucosylceramidase, putative	0.0251	0.7898	0.894
Brugia malayi	latrophilin 2 splice variant baaae	0.0033	0.0692	0.0783
Trypanosoma brucei	DNA polymerase kappa, putative	0.0013	0.0029	0.0113
Schistosoma mansoni	hypothetical protein	0.0033	0.0692	0.0692
Treponema pallidum	glucose-6-phosphate 1-dehydrogenase	0.009	0.2594	0.5
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Loa Loa (eye worm)	glutaminase 2	0.0279	0.8835	0.8835
Schistosoma mansoni	hypothetical protein	0.0015	0.0103	0.0103
Plasmodium falciparum	GTP-binding nuclear protein RAN/TC4	0.0022	0.0313	0.1096
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0684	0.0775
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Echinococcus granulosus	transcription factor btf3	0.0036	0.0778	0.0778
Trichomonas vaginalis	glucosylceramidase, putative	0.0164	0.5044	0.5708
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0024	0.0386	0.0437
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.0019	0.0224	0.0224
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0019	0.0224	0.0865
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0024	0.0386	0.0437
Echinococcus multilocularis	GTP binding nuclear protein Ran	0.0022	0.0313	0.0313
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0048	0.1199	0.1357
Echinococcus granulosus	apoptotic protease activating factor 1	0.003	0.0602	0.0602
Plasmodium vivax	small ubiquitin-related modifier, putative	0.0053	0.1358	0.4748
Giardia lamblia	Glucose-6-phosphate 1-dehydrogenase	0.0099	0.2861	1

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 1.05 10^-3mmol/L	Inhibition of pieris rapae Phenoloxidase	ChEMBL.	17258462
Log IC50 (binding)	= 5.98	Inhibition of pieris rapae Phenoloxidase	ChEMBL.	17258462

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 436599