Detailed information for compound 436928

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 580.803 | Formula: C37H48N4O2
  • H donors: 1 H acceptors: 2 LogP: 4.84 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: CN(CC(=O)N1CCC[C@H]2[C@]31CC(=C[C@H]2Cc1c3ccc(=O)[nH]1)C)CCCCCCN(Cc1cccc2c1cccc2)C
  • InChi: 1S/C37H48N4O2/c1-27-22-30-23-34-33(17-18-35(42)38-34)37(24-27)32(30)16-11-21-41(37)36(43)26-40(3)20-9-5-4-8-19-39(2)25-29-14-10-13-28-12-6-7-15-31(28)29/h6-7,10,12-15,17-18,22,30,32H,4-5,8-9,11,16,19-21,23-26H2,1-3H3,(H,38,42)/t30-,32+,37+/m0/s1
  • InChiKey: LRAHGMFKJZCSRN-WHMCYVJPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Acetylcholinesterase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) carboxylesterase Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis carboxylesterase 5A Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma japonicum ko:K01049 acetylcholinesterase [EC3.1.1.7], putative Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma japonicum Acetylcholinesterase 1 precursor, putative Get druggable targets OG5_126875 All targets in OG5_126875
Brugia malayi Carboxylesterase family protein Get druggable targets OG5_126875 All targets in OG5_126875
Brugia malayi Carboxylesterase family protein Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) acetylcholinesterase 1 Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus carboxylesterase 5A Get druggable targets OG5_126875 All targets in OG5_126875
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) hypothetical protein Acetylcholinesterase   614 aa 570 aa 25.4 %
Onchocerca volvulus Molybdopterin synthase catalytic subunit homolog Acetylcholinesterase   614 aa 564 aa 29.8 %
Echinococcus multilocularis neuroligin Acetylcholinesterase   614 aa 496 aa 24.0 %
Loa Loa (eye worm) hypothetical protein Acetylcholinesterase   614 aa 574 aa 24.0 %
Brugia malayi Carboxylesterase family protein Acetylcholinesterase   614 aa 507 aa 26.4 %
Onchocerca volvulus Acetylcholinesterase   614 aa 583 aa 30.7 %
Drosophila melanogaster CG10175 gene product from transcript CG10175-RE Acetylcholinesterase   614 aa 547 aa 32.5 %
Onchocerca volvulus Acetylcholinesterase   614 aa 632 aa 25.6 %
Echinococcus granulosus BC026374 protein S09 family Acetylcholinesterase   614 aa 642 aa 34.1 %
Echinococcus multilocularis BC026374 protein (S09 family) Acetylcholinesterase   614 aa 642 aa 34.0 %
Onchocerca volvulus Acetylcholinesterase   614 aa 581 aa 27.0 %
Brugia malayi Carboxylesterase family protein Acetylcholinesterase   614 aa 573 aa 30.5 %
Onchocerca volvulus Putative nuclear protein Acetylcholinesterase   614 aa 577 aa 40.7 %
Onchocerca volvulus Carnitine O-palmitoyltransferase 2, mitochondrial homolog Acetylcholinesterase   614 aa 531 aa 39.7 %
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) Acetylcholinesterase   614 aa 602 aa 24.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni endoplasmin 0.0136 0.0129 0.0128
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0116 0.0105 0.0765
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1136 0.1294 1
Toxoplasma gondii subtilisin SUB12 0.0132 0.0125 0.0433
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0038 0.0014 0.0015
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Plasmodium vivax apical membrane antigen 1 0.0279 0.0296 0.1038
Brugia malayi metabotropic glutamate receptor type 2 0.0034 0.001 0.0011
Onchocerca volvulus 0.0925 0.1048 0.8677
Entamoeba histolytica tubulin family protein 0.0225 0.0232 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.0009
Toxoplasma gondii type I fatty acid synthase, putative 0.0058 0.0039 0.0128
Echinococcus multilocularis 0.0092 0.0078 0.0076
Schistosoma mansoni tubulin subunit beta 0.0225 0.0232 0.0231
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0925 0.1048 0.8677
Schistosoma mansoni integrin alpha-ps 0.0272 0.0287 0.0286
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0029 0.0005 0.0004
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0118 0.0108 0.0353
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.277 0.3198 0.3197
Brugia malayi hypothetical protein 0.0027 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0043 0.0292
Loa Loa (eye worm) subtilase 0.0118 0.0108 0.0129
Leishmania major beta tubulin 0.0225 0.0232 1
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.029 0.1019
Onchocerca volvulus 0.0035 0.0011 0.0072
Entamoeba histolytica cell division protein kinase 2, putative 0.0047 0.0026 0.1062
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0002 0.0002
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0118 0.0108 0.0131
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0925 0.1048 0.1047
Trypanosoma brucei heat shock protein, putative 0.0136 0.0129 0.1091
Plasmodium vivax glutathione reductase, putative 0.0062 0.0043 0.0143
Brugia malayi EGF-like domain containing protein 0.0132 0.0124 0.015
Schistosoma mansoni alpha-1 adrenergic receptor 0.0925 0.1048 0.1047
Loa Loa (eye worm) hypothetical protein 0.0193 0.0195 0.0235
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0011 0.0035
Loa Loa (eye worm) glutaminase 2 0.0541 0.0601 0.0732
Echinococcus granulosus furin 0.277 0.3198 0.3197
Echinococcus multilocularis cyclins 0.0087 0.0071 0.007
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0172 0.0171 0.0596
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Brugia malayi Sushi domain 0.0047 0.0026 0.003
Echinococcus multilocularis fmrfamide receptor 0.0925 0.1048 0.1047
Mycobacterium ulcerans Type I modular polyketide synthase 0.0079 0.0063 0.0203
Giardia lamblia High cysteine protein 0.0132 0.0124 0.1006
Echinococcus multilocularis DNA excision repair protein ERCC 1 0.0031 0.0007 0.0006
Toxoplasma gondii heat shock protein 75, putative 0.004 0.0017 0.0052
Echinococcus granulosus integrin alpha ps 0.0272 0.0287 0.0286
Entamoeba histolytica serine/threonine protein kinase, putative 0.0093 0.0079 0.3358
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0172 0.0171 0.729
Mycobacterium leprae Probable lipase LipE 0.0035 0.0011 0.0035
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.032 0.0344 0.1118
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0068 0.005 0.0162
Onchocerca volvulus 0.0925 0.1048 0.8677
Onchocerca volvulus 0.0181 0.0181 0.1486
Leishmania major RAD51/dmc1 protein 0.0046 0.0024 0.0857
Loa Loa (eye worm) glutaminase 0.0541 0.0601 0.0732
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0077 0.006 0.007
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0043 0.0292
Echinococcus granulosus cyclin B3 1 0.0087 0.0071 0.007
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0132 0.0124 0.043
Schistosoma mansoni protein kinase 0.0126 0.0118 0.0117
Schistosoma mansoni hypothetical protein 0.0418 0.0457 0.0456
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0081 0.008
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0134 0.0126 0.0125
Giardia lamblia Furin precursor putative serine protease 0.0536 0.0595 0.5055
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.006 0.0041 0.1385
Echinococcus granulosus neuropeptides capa receptor 0.0925 0.1048 0.1047
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0034 0.001 0.0011
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.018 0.0629
Echinococcus multilocularis integrin alpha ps 0.0272 0.0287 0.0286
Plasmodium falciparum apical membrane antigen 1 0.0279 0.0296 0.1038
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0011 0.0035
Plasmodium vivax aspartyl protease, putative 0.0607 0.0677 0.2389
Echinococcus granulosus fmrfamide receptor 0.0925 0.1048 0.1047
Brugia malayi Kelch motif family protein 0.1096 0.1248 0.1524
Brugia malayi hypothetical protein 0.0047 0.0026 0.003
Schistosoma mansoni hypothetical protein 0.0925 0.1048 0.1047
Schistosoma mansoni septate junction protein 0.0027 0.0002 0.0001
Schistosoma mansoni tyrosine kinase 0.0095 0.0081 0.008
Schistosoma mansoni aminopeptidase A (M01 family) 0.006 0.0041 0.004
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0011 0.0011
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0925 0.1048 0.1047
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0049 0.0028 0.0027
Loa Loa (eye worm) TK/INSR protein kinase 0.0095 0.0081 0.0096
Loa Loa (eye worm) hypothetical protein 0.0132 0.0124 0.0148
Plasmodium falciparum plasmepsin VI 0.2451 0.2827 1
Brugia malayi metalloprotease 0.0049 0.0028 0.0033
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0084 0.0069 0.0222
Echinococcus granulosus Furin 1 0.0654 0.0733 0.0732
Echinococcus granulosus cyclin B 0.0181 0.0181 0.018
Loa Loa (eye worm) hypothetical protein 0.0142 0.0135 0.0162
Echinococcus multilocularis membrane associated guanylate kinase, WW and PDZ 0.0049 0.0028 0.0027
Schistosoma mansoni amine GPCR 0.0925 0.1048 0.1047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0925 0.1048 0.1047
Plasmodium vivax plasmepsin IV, putative 0.2451 0.2827 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Echinococcus granulosus ubiquitin conjugating enzyme e2 i 0.0051 0.003 0.0029
Brugia malayi G protein-coupled receptor 0.0925 0.1048 0.1279
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0011 0.0036
Echinococcus multilocularis g protein coupled receptor 0.0925 0.1048 0.1047
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0047 0.0026 0.0028
Echinococcus multilocularis NMDA receptor 0.0079 0.0062 0.0061
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0058 0.0038 0.0037
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0172 0.0171 0.017
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0036 0.012
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.2451 0.2827 1
Schistosoma mansoni glutaminase 0.0541 0.0601 0.06
Echinococcus multilocularis G-protein coupled receptor, putative 0.0925 0.1048 0.1047
Loa Loa (eye worm) heat shock protein 90 0.0136 0.0129 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0079 0.0271
Echinococcus multilocularis geminin 0.0263 0.0276 0.0275
Toxoplasma gondii heat shock protein 90, putative 0.0136 0.0129 0.0447
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0027 0.0002 0.0001
Brugia malayi Peptidase family M1 containing protein 0.0172 0.0171 0.0207
Echinococcus granulosus Tubulin beta 2C chain 0.0225 0.0232 0.0231
Loa Loa (eye worm) heat shock protein 75 0.004 0.0017 0.0018
Echinococcus granulosus nmda type glutamate receptor 0.0034 0.001 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.018 0.0629
Brugia malayi larval opioid receptor 0.0925 0.1048 0.1279
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0671 0.0752 0.0917
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0005 0.001
Schistosoma mansoni hypothetical protein 0.013 0.0122 0.0121
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Leishmania major beta tubulin 0.0225 0.0232 1
Loa Loa (eye worm) runx1 0.0056 0.0036 0.0041
Onchocerca volvulus 0.0037 0.0013 0.0089
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0607 0.0677 0.0676
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0051 0.003 0.126
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.2451 0.2827 0.2826
Trypanosoma brucei beta tubulin 0.0225 0.0232 0.2054
Schistosoma mansoni histamine h1 receptor 0.0925 0.1048 0.1047
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Schistosoma mansoni ADAMTS14 peptidase (M12 family) 0.0049 0.0028 0.0027
Echinococcus granulosus 7TM GPCR rhodopsin 0.0925 0.1048 0.1047
Loa Loa (eye worm) hypothetical protein 0.0135 0.0128 0.0153
Plasmodium falciparum tubulin beta chain 0.0225 0.0232 0.0814
Onchocerca volvulus 0.0047 0.0026 0.0193
Mycobacterium ulcerans beta-lactamase 0.0035 0.0011 0.0035
Echinococcus granulosus leucine aminopeptidase protein 0.0102 0.009 0.0089
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0134 0.0126 0.0125
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0159 0.0155 0.0506
Loa Loa (eye worm) hypothetical protein 0.0046 0.0024 0.0026
Brugia malayi Cyclin, N-terminal domain containing protein 0.0181 0.0181 0.022
Echinococcus granulosus g-protein coupled receptor 0.0925 0.1048 0.1047
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0029 0.0005 0.0008
Echinococcus granulosus beta tubulin 0.0225 0.0232 0.0231
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0925 0.1048 0.1047
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0111 0.01 0.4059
Echinococcus multilocularis cyclin dependent kinase 1 0.0047 0.0026 0.0025
Schistosoma mansoni tyrosine kinase 0.0036 0.0012 0.0011
Brugia malayi hypothetical protein 0.0172 0.0171 0.0207
Toxoplasma gondii subtilisin SUB2 0.0118 0.0108 0.0375
Onchocerca volvulus 0.0143 0.0137 0.1116
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Schistosoma mansoni hypothetical protein 0.0671 0.0752 0.0751
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.0009
Loa Loa (eye worm) carboxylesterase 0.0082 0.0066 0.0077
Trypanosoma brucei beta tubulin 0.0225 0.0232 0.2054
Leishmania major beta tubulin 0.0225 0.0232 1
Leishmania major beta tubulin 0.0225 0.0232 1
Loa Loa (eye worm) endoprotease bli-4 0.277 0.3198 0.3906
Loa Loa (eye worm) beta-tubulin 0.0225 0.0232 0.0281
Echinococcus granulosus glutamate NMDA receptor subunit 0.0593 0.0661 0.066
Echinococcus multilocularis neuropeptide receptor A26 0.1381 0.158 0.1579
Loa Loa (eye worm) hypothetical protein 0.0459 0.0505 0.0614
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.006 0.0041 0.0136
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0043 0.1463
Plasmodium vivax endoplasmin, putative 0.0136 0.0129 0.0447
Loa Loa (eye worm) hypothetical protein 0.5852 0.679 0.8297
Mycobacterium tuberculosis Probable holliday junction DNA helicase RuvA 0.0031 0.0007 0.0023
Loa Loa (eye worm) TYRA-2 protein 0.0925 0.1048 0.1278
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.006 0.0041 0.1585
Echinococcus granulosus fibrillin 2 0.0132 0.0124 0.0123
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1684 0.1932 0.6833
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0134 0.0126 0.0125
Brugia malayi aspartic protease BmAsp-2, identical 0.0607 0.0677 0.0826
Trichomonas vaginalis heat shock protein, putative 0.0116 0.0105 0.0365
Loa Loa (eye worm) hypothetical protein 0.0105 0.0092 0.011
Trichomonas vaginalis cyclin A, putative 0.0181 0.0181 0.0634
Trypanosoma brucei heat shock protein, putative 0.0136 0.0129 0.1091
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0002 0.0002
Trichomonas vaginalis tubulin gamma chain, putative 0.0225 0.0232 0.0814
Brugia malayi Angiotensin-converting enzyme family protein 0.0645 0.0722 0.0881
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0037 0.0013 0.0015
Loa Loa (eye worm) RGC/RGC protein kinase 0.0036 0.0012 0.0012
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0002 0.0002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0925 0.1048 0.1047
Echinococcus multilocularis tissue type plasminogen activator 0.0054 0.0033 0.0032
Entamoeba histolytica hypothetical protein 0.0046 0.0024 0.099
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0029 0.0005 0.0008
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0172 0.0171 0.7226
Brugia malayi hypothetical protein 0.0034 0.001 0.0011
Echinococcus multilocularis tyrosine kinase 0.0036 0.0012 0.0011
Onchocerca volvulus 0.0925 0.1048 0.8677
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0607 0.0677 0.0825
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0925 0.1048 0.1278
Plasmodium falciparum plasmepsin VIII, putative 0.0607 0.0677 0.2389
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0111 0.01 0.0099
Echinococcus multilocularis fibrillin 1 0.0145 0.0139 0.0138
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0011 0.0035
Echinococcus granulosus GPCR family 2 0.0671 0.0752 0.0751
Onchocerca volvulus 0.0035 0.0011 0.0072
Trypanosoma cruzi heat shock protein 85, putative 0.0116 0.0105 0.4288
Echinococcus multilocularis cyclins 0.0087 0.0071 0.007
Onchocerca volvulus 0.0925 0.1048 0.8677
Brugia malayi hypothetical protein 0.0925 0.1048 0.1279
Schistosoma mansoni dihydroceramide desaturase 0.0074 0.0057 0.0056
Entamoeba histolytica heat shock protein 90, putative 0.0136 0.0129 0.5512
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0118 0.0108 0.0107
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0925 0.1048 0.1047
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Trypanosoma brucei aminopeptidase, putative 0.006 0.0041 0.0276
Echinococcus granulosus neuroendocrine convertase 2 0.1741 0.1999 0.1998
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0047 0.0026 0.0082
Loa Loa (eye worm) glutamate receptor 2 0.01 0.0087 0.0103
Brugia malayi Melatonin receptor type 1A 0.0925 0.1048 0.1279
Echinococcus multilocularis Tubulin beta 2C chain 0.0225 0.0232 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0108 0.0375
Onchocerca volvulus 0.0925 0.1048 0.8677
Trypanosoma brucei heat shock protein, putative 0.0136 0.0129 0.1091
Giardia lamblia Heat shock protein HSP 90-alpha 0.0136 0.0129 0.1047
Mycobacterium ulcerans Type I modular polyketide synthase 0.0079 0.0063 0.0203
Loa Loa (eye worm) hypothetical protein 0.0037 0.0013 0.0013
Schistosoma mansoni biogenic amine (5HT) receptor 0.0925 0.1048 0.1047
Loa Loa (eye worm) hypothetical protein 0.0179 0.0179 0.0216
Trichomonas vaginalis cyclins, putative 0.0181 0.0181 0.0634
Trichomonas vaginalis cyclin B, putative 0.0181 0.0181 0.0634
Echinococcus granulosus somatostatin receptor 0.0925 0.1048 0.1047
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0172 0.0171 0.017
Echinococcus granulosus rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Echinococcus multilocularis beta adrenergic receptor kinase 0.0095 0.0081 0.008
Schistosoma mansoni kinase 0.0048 0.0026 0.0025
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Loa Loa (eye worm) reprolysin 0.0179 0.0179 0.0216
Plasmodium vivax aspartyl proteinase, putative 0.2451 0.2827 1
Plasmodium falciparum endoplasmin, putative 0.006 0.004 0.0135
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0038 0.0014 0.0042
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0925 0.1048 0.1047
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0249 0.026 0.0259
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0925 0.1048 0.1047
Loa Loa (eye worm) glutathione reductase 0.0062 0.0043 0.0049
Plasmodium falciparum plasmepsin V 0.0607 0.0677 0.2389
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0011 0.005
Brugia malayi latrophilin 2 splice variant baaae 0.1449 0.1659 0.2026
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0194 0.0197 0.0196
Echinococcus multilocularis acetylcholinesterase 0.0082 0.0066 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0043 0.0292
Brugia malayi hypothetical protein 0.0925 0.1048 0.1279
Echinococcus multilocularis cpg binding protein 0.0031 0.0007 0.0005
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0051 0.003 0.0097
Echinococcus multilocularis heat shock protein 0.0136 0.0129 0.0128
Trypanosoma brucei heat shock protein 90, putative 0.0136 0.0129 0.1091
Echinococcus multilocularis orexin receptor type 2 0.0925 0.1048 0.1047
Giardia lamblia hypothetical protein 0.0132 0.0124 0.1006
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0047 0.0026 0.0025
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0038 0.0014 0.0042
Echinococcus multilocularis g protein coupled receptor 0.0925 0.1048 0.1047
Trichomonas vaginalis cyclins, putative 0.0181 0.0181 0.0634
Plasmodium falciparum SUMO-conjugating enzyme UBC9 0.0051 0.003 0.0099
Echinococcus granulosus protein will die slowly 0.0201 0.0205 0.0204
Echinococcus multilocularis neuropeptide s receptor 0.1381 0.158 0.1579
Trichomonas vaginalis cyclins, putative 0.0087 0.0071 0.0244
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0058 0.0038 0.0037
Brugia malayi ADAM-TS Spacer 1 family protein 0.0105 0.0092 0.0111
Trichomonas vaginalis heat shock protein, putative 0.006 0.004 0.0135
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0011 0.001
Brugia malayi Hsp90 protein 0.004 0.0017 0.002
Brugia malayi glutathione reductase 0.0062 0.0043 0.0051
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0051 0.003 0.1123
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0925 0.1048 0.1047
Schistosoma mansoni ATP-binding cassette transporter 0.0103 0.009 0.0089
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0925 0.1048 0.1047
Echinococcus granulosus g protein coupled receptor 0.0925 0.1048 0.1047
Echinococcus granulosus tubulin beta 4A class IVa 0.0225 0.0232 0.0231
Echinococcus multilocularis c4b binding protein beta chain 0.0047 0.0026 0.0024
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0002 0.0055
Loa Loa (eye worm) hypothetical protein 0.013 0.0122 0.0146
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.004 0.0017 0.0122
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0118 0.0108 0.0351
Schistosoma mansoni neuropeptide receptor 0.0925 0.1048 0.1047
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0654 0.0733 0.2586
Brugia malayi putative neuropeptide receptor 0.0925 0.1048 0.1279
Brugia malayi Latrophilin receptor protein 2 0.0671 0.0752 0.0917
Schistosoma mansoni neuropeptide receptor 0.0925 0.1048 0.1047
Echinococcus granulosus Tubulin beta 2C chain 0.0225 0.0232 0.0231
Plasmodium falciparum subtilisin-like protease 3 0.0118 0.0108 0.0375
Trypanosoma cruzi DNA repair protein RAD51, putative 0.0046 0.0024 0.064
Echinococcus multilocularis fmrfamide receptor 0.0925 0.1048 0.1047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0043 0.0292
Brugia malayi MH2 domain containing protein 0.0088 0.0073 0.0087
Schistosoma mansoni integrin alpha-ps 0.0142 0.0135 0.0134
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0082 0.0066 0.0065
Brugia malayi sulfakinin receptor protein 0.0925 0.1048 0.1279
Brugia malayi Carboxylesterase family protein 0.0082 0.0066 0.0079
Brugia malayi Pepsin A precursor 0.0607 0.0677 0.0826
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Schistosoma mansoni hypothetical protein 0.0058 0.0038 0.0037
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0064 0.0045 0.0148
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Loa Loa (eye worm) tubulin beta-1 chain 0.0225 0.0232 0.0281
Leishmania major beta tubulin 0.0225 0.0232 1
Echinococcus granulosus membrane bound transcription factor site 1 0.0118 0.0108 0.0107
Echinococcus multilocularis cyclin dependent kinase 0.0047 0.0026 0.0025
Giardia lamblia Cyclin A 0.0087 0.0071 0.0553
Echinococcus granulosus adam 0.0366 0.0397 0.0396
Echinococcus granulosus neuropeptide s receptor 0.1381 0.158 0.1579
Loa Loa (eye worm) hypothetical protein 0.0047 0.0026 0.0028
Echinococcus granulosus dnaJ subfamily B 0.0418 0.0457 0.0456
Echinococcus multilocularis glutamate receptor 2 0.01 0.0087 0.0086
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Loa Loa (eye worm) hypothetical protein 0.0111 0.01 0.012
Brugia malayi Metabotropic glutamate receptor precursor. 0.0034 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.018 0.0629
Brugia malayi aspartic protease BmAsp-1, identical 0.0607 0.0677 0.0826
Schistosoma mansoni metabotropic glutamate receptor 0.0034 0.001 0.0009
Plasmodium falciparum subtilisin-like protease 1 0.0118 0.0108 0.0375
Loa Loa (eye worm) hypothetical protein 0.0607 0.0677 0.0825
Leishmania major cyclin 0.0181 0.0181 0.7759
Plasmodium vivax subtilisin-like protease 1 0.0118 0.0108 0.0375
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.017 0.0169 0.0549
Brugia malayi hypothetical protein 0.0047 0.0026 0.003
Toxoplasma gondii aspartyl protease ASP3 0.0857 0.097 0.3424
Echinococcus multilocularis fibrillin 2 0.0132 0.0124 0.0123
Toxoplasma gondii aminopeptidase n, putative 0.006 0.0041 0.0136
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0079 0.0062 0.0061
Brugia malayi Guanylyl cyclase protein 23 0.0036 0.0012 0.0013
Trypanosoma brucei cdc2-related kinase 3 0.0047 0.0026 0.0136
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0031
Schistosoma mansoni neuropeptide receptor 0.0925 0.1048 0.1047
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0036 0.0035
Trypanosoma cruzi Heat shock protein 83, putative 0.0136 0.0129 0.5333
Loa Loa (eye worm) WD40 repeat protein 0.0201 0.0205 0.0247
Echinococcus granulosus cpg binding protein 0.0031 0.0007 0.0005
Echinococcus granulosus glutamate receptor 2 0.0055 0.0035 0.0034
Treponema pallidum heat shock protein 90 0.0116 0.0105 0.0797
Toxoplasma gondii type I fatty acid synthase, putative 0.0084 0.0069 0.0235
Mycobacterium tuberculosis Probable thioesterase TesA 0.0068 0.005 0.0163
Leishmania major hypothetical protein, conserved 0.0054 0.0033 0.1232
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0025 0.008
Brugia malayi hypothetical protein 0.006 0.0041 0.0048
Plasmodium falciparum M1-family alanyl aminopeptidase 0.006 0.0041 0.0136
Loa Loa (eye worm) hypothetical protein 0.2451 0.2827 0.3452
Plasmodium vivax aspartyl protease, putative 0.0857 0.097 0.3424
Trypanosoma brucei heat shock protein 90, putative 0.0136 0.0129 0.1091
Trichomonas vaginalis heat shock protein, putative 0.0116 0.0105 0.0365
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0047 0.0026 0.0028
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0026 0 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.029 0.1019
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0051 0.003 0.0912
Schistosoma mansoni serine-type protease inhibitor 0.4976 0.5769 0.5768
Plasmodium falciparum heat shock protein 90 0.0136 0.0129 0.0447
Leishmania major cathepsin L-like protease 0.0062 0.0043 0.1661
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Echinococcus multilocularis somatostatin receptor 0.0925 0.1048 0.1047
Schistosoma mansoni opsin-like receptor 0.0925 0.1048 0.1047
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0925 0.1048 0.1278
Loa Loa (eye worm) hypothetical protein 0.0607 0.0677 0.0825
Toxoplasma gondii beta-tubulin, putative 0.0225 0.0232 0.0814
Mycobacterium leprae 3-dehydroquinate dehydratase AroD (AroQ) (3-dehydroquinase) (Type II DHQase) 0.2661 0.3071 1
Brugia malayi hypothetical protein 0.0047 0.0026 0.003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0925 0.1048 0.1047
Onchocerca volvulus Fatty acid synthase homolog 0.0148 0.0143 0.1166
Loa Loa (eye worm) rad51 0.0046 0.0024 0.0027
Loa Loa (eye worm) hypothetical protein 0.1086 0.1236 0.1508
Brugia malayi glutaminase DH11.1 0.0541 0.0601 0.0733
Toxoplasma gondii apical membrane antigen 1 domain-containing protein 0.0279 0.0296 0.1038
Echinococcus granulosus carboxylesterase 5A 0.0082 0.0066 0.0065
Echinococcus granulosus G protein coupled receptor kinase 1 0.0085 0.007 0.0069
Schistosoma mansoni thyroid hormone receptor 0.014 0.0133 0.0132
Echinococcus multilocularis Tubulin beta 2C chain 0.0225 0.0232 0.0231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0043 0.0292
Mycobacterium ulcerans Type I modular polyketide synthase 0.0079 0.0063 0.0203
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.2451 0.2827 0.2826
Trichomonas vaginalis set domain proteins, putative 0.0234 0.0243 0.0851
Schistosoma mansoni hypothetical protein 0.0058 0.0038 0.0037
Echinococcus granulosus tm gpcr rhodopsin 0.0925 0.1048 0.1047
Plasmodium falciparum plasmepsin I 0.2451 0.2827 1
Leishmania major beta tubulin 0.0225 0.0232 1
Leishmania major beta tubulin 0.0225 0.0232 1
Echinococcus granulosus neuropeptide Y receptor 0.0925 0.1048 0.1047
Schistosoma mansoni neuropeptide receptor 0.8608 1 1
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Schistosoma mansoni hypothetical protein 0.0201 0.0205 0.0204
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0536 0.0595 0.2097
Trichomonas vaginalis cyclin B, putative 0.0181 0.0181 0.0634
Echinococcus granulosus integrin alpha ps 0.013 0.0122 0.0121
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0079 0.0063 0.0075
Echinococcus granulosus cyclins 0.0087 0.0071 0.007
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Onchocerca volvulus Neuropeptide F receptor homolog 0.0925 0.1048 0.8677
Onchocerca volvulus 0.0925 0.1048 0.8677
Echinococcus multilocularis heat shock protein 90 0.0136 0.0129 0.0128
Schistosoma mansoni hypothetical protein 0.0925 0.1048 0.1047
Trichomonas vaginalis heat shock protein, putative 0.0136 0.0129 0.0447
Echinococcus multilocularis rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Brugia malayi Reprolysin 0.0105 0.0093 0.0112
Brugia malayi Cyclin, N-terminal domain containing protein 0.0087 0.0071 0.0086
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0671 0.0752 0.0751
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0172 0.0171 0.017
Brugia malayi Dopamine receptor protein 1 0.0925 0.1048 0.1279
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0925 0.1048 0.1047
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0925 0.1048 0.1047
Echinococcus multilocularis membrane associated guanylate kinase ww and pdz 0.0049 0.0028 0.0027
Chlamydia trachomatis glutamine binding protein 0.017 0.0169 0.1255
Schistosoma mansoni opsin-like receptor 0.0925 0.1048 0.1047
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0925 0.1048 0.1279
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0095 0.0081 0.0096
Onchocerca volvulus 0.0036 0.0012 0.0079
Onchocerca volvulus 0.0337 0.0363 0.2994
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0033 0.0009 0.0007
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0134 0.0126 0.0125
Brugia malayi GnHR receptor homolog 0.4568 0.5294 0.6468
Leishmania major heat shock protein, putative 0.004 0.0017 0.0546
Echinococcus granulosus neuropeptide Y receptor 0.0925 0.1048 0.1047
Echinococcus granulosus neuropeptide FF receptor 2 0.0925 0.1048 0.1047
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0025 0.008
Brugia malayi Integrin beta pat-3 precursor 0.7048 0.8183 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.1061 0.1207 0.1206
Toxoplasma gondii subtilisin SUB9 0.0118 0.0108 0.0375
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1684 0.1932 0.6833
Schistosoma mansoni adenoreceptor 0.0925 0.1048 0.1047
Brugia malayi Receptor family ligand binding region containing protein 0.0036 0.0012 0.0013
Echinococcus multilocularis protein arginine methyltransferase 0.0029 0.0005 0.0004
Leishmania major beta tubulin 0.0225 0.0232 1
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.006 0.0041 0.004
Loa Loa (eye worm) hypothetical protein 0.1061 0.1207 0.1472
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0134 0.0126 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0925 0.1048 0.1047
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.029 0.1019
Trypanosoma brucei polo-like protein kinase 0.0093 0.0079 0.0628
Toxoplasma gondii subtilisin SUB4 0.0118 0.0108 0.0375
Echinococcus multilocularis integrin beta 2 0.5196 0.6025 0.6024
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Echinococcus granulosus 7tm_1 domain containing protein 0.0925 0.1048 0.1047
Leishmania major beta tubulin 0.0225 0.0232 1
Trypanosoma brucei cdc2-related kinase 1 0.0047 0.0026 0.0136
Echinococcus granulosus rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Leishmania major beta tubulin 0.0225 0.0232 1
Echinococcus granulosus cyclin dependent kinase 1 0.0047 0.0026 0.0025
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0036 0.0035
Plasmodium falciparum cyclin 0.0087 0.0071 0.0244
Echinococcus granulosus metabotropic glutamate receptor 2 0.0034 0.001 0.0009
Echinococcus multilocularis serotonin receptor 0.0925 0.1048 0.1047
Echinococcus granulosus tachykinin peptides receptor 99D 0.0925 0.1048 0.1047
Echinococcus multilocularis 0.0069 0.005 0.0049
Schistosoma mansoni heat shock protein 0.0136 0.0129 0.0128
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0925 0.1048 0.1047
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1136 0.1294 1
Brugia malayi Pre-SET motif family protein 0.003 0.0005 0.0005
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0116 0.0105 0.0343
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0005 0.0004
Echinococcus multilocularis integrin alpha 3 0.0465 0.0512 0.0511
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Brugia malayi beta-lactamase family protein 0.0035 0.0011 0.0012
Onchocerca volvulus Glucosylceramidase homolog 0.018 0.018 0.1475
Echinococcus granulosus Tubulin beta 2C chain 0.0225 0.0232 0.0231
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0925 0.1048 0.1278
Trichomonas vaginalis cyclin B, putative 0.0181 0.0181 0.0634
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.0816 0.0921 0.2999
Brugia malayi Eukaryotic aspartyl protease family protein 0.0607 0.0677 0.0826
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0074 0.0057 0.0056
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0172 0.0171 0.017
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0038 0.0014 0.0042
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.006 0.0041 0.0136
Loa Loa (eye worm) leukotriene A4 hydrolase 0.006 0.0041 0.0047
Plasmodium falciparum plasmepsin X 0.0857 0.097 0.3424
Schistosoma mansoni DNA repair protein RAD51 0.0046 0.0024 0.0023
Echinococcus multilocularis cyclins 0.0087 0.0071 0.007
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0034 0.001 0.0009
Echinococcus granulosus integrin alpha 3 0.0465 0.0512 0.0511
Mycobacterium leprae Polyketide synthase Pks13 0.012 0.011 0.0357
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Onchocerca volvulus 0.0925 0.1048 0.8677
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0925 0.1048 0.1279
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0172 0.0171 0.017
Leishmania major extracellular receptor, putative 0.0034 0.001 0.0232
Trichomonas vaginalis hypothetical protein 0.0132 0.0124 0.043
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0925 0.1048 0.1279
Loa Loa (eye worm) hypothetical protein 0.0118 0.0108 0.0129
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Brugia malayi Protein kinase domain containing protein 0.0095 0.0081 0.0098
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.006 0.0041 0.1385
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0925 0.1048 0.1047
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0038 0.0014 0.0193
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1136 0.1294 0.4214
Toxoplasma gondii subtilisin SUB10 0.0118 0.0108 0.0375
Loa Loa (eye worm) pigment dispersing factor receptor c 0.2119 0.244 0.298
Schistosoma mansoni hypothetical protein 0.0925 0.1048 0.1047
Echinococcus granulosus tissue type plasminogen activator 0.0054 0.0033 0.0032
Trichomonas vaginalis cyclin D, putative 0.0087 0.0071 0.0244
Loa Loa (eye worm) TATA binding protein associated factor 0.006 0.0041 0.0047
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0172 0.0171 0.017
Brugia malayi ADAMTS-like protease 0.0105 0.0092 0.0111
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0011 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Plasmodium vivax aspartyl protease, putative 0.0857 0.097 0.3424
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0038 0.0014 0.0013
Schistosoma mansoni tubulin subunit beta 0.0225 0.0232 0.0231
Plasmodium vivax merozoite adhesive erythrocytic binding protein 0.0066 0.0047 0.0159
Brugia malayi Kringle domain containing protein 0.0054 0.0033 0.0039
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Loa Loa (eye worm) aspartyl protease 6 0.0607 0.0677 0.0825
Echinococcus multilocularis glutamate receptor 2 0.0055 0.0035 0.0034
Onchocerca volvulus 0.1061 0.1207 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0036 0.1183
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0011 0.0031
Trichomonas vaginalis esterase, putative 0.0035 0.0011 0.0031
Echinococcus granulosus collagen alpha 1VII chain 0.0027 0.0002 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0925 0.1048 0.1047
Echinococcus multilocularis cyclins 0.0087 0.0071 0.007
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0607 0.0677 0.0676
Loa Loa (eye worm) RGC/RGC protein kinase 0.0036 0.0012 0.0012
Brugia malayi von Willebrand Factor 0.0027 0.0002 0.0002
Toxoplasma gondii apical membrane antigen 1 protein 0.0066 0.0047 0.0159
Echinococcus granulosus geminin 0.0263 0.0276 0.0275
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.4403 0.5101 0.5101
Schistosoma mansoni neuropeptide F-like receptor 0.0925 0.1048 0.1047
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0172 0.0171 0.017
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.017 0.0169 0.1286
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0034 0.001 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0011 0.005
Toxoplasma gondii ABC1 family protein 0.0035 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Trichomonas vaginalis ubiquitin-conjugating enzyme rad6, putative 0.0051 0.003 0.0099
Toxoplasma gondii meiotic recombination protein DMC1 family protein 0.0046 0.0024 0.0077
Echinococcus multilocularis neuroendocrine convertase 2 0.1741 0.1999 0.1998
Loa Loa (eye worm) hypothetical protein 0.0037 0.0013 0.0013
Schistosoma mansoni excision repair cross-complementing 1 ercc1 0.0031 0.0007 0.0006
Echinococcus multilocularis g protein coupled receptor 0.0925 0.1048 0.1047
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0027 0.0002 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0925 0.1048 0.1047
Mycobacterium ulcerans aminopeptidase N PepN 0.0172 0.0171 0.0555
Trypanosoma cruzi cdc2-related kinase 3 0.0047 0.0026 0.0706
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0077 0.006 0.0195
Loa Loa (eye worm) aminopeptidase N 0.0172 0.0171 0.0206
Schistosoma mansoni lozenge 0.0056 0.0036 0.0035
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0005 0.0004
Schistosoma mansoni site-1 peptidase (S08 family) 0.0118 0.0108 0.0107
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0593 0.0661 0.066
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.018 0.0629
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0047 0.0026 0.0922
Echinococcus granulosus peptide allatostatin:somatostatin 0.0925 0.1048 0.1047
Echinococcus multilocularis tubulin beta 1 chain 0.0225 0.0232 0.0231
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0038 0.0014 0.0569
Loa Loa (eye worm) peptidase family M1 containing protein 0.0225 0.0233 0.0282
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0172 0.0171 0.017
Schistosoma mansoni hypothetical protein 0.0027 0.0002 0.0001
Mycobacterium leprae Possible secreted protease 0.0118 0.0108 0.0351
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.011 0.0098 0.0117
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0191 0.0669
Plasmodium falciparum heat shock protein 90, putative 0.004 0.0017 0.0052
Trichomonas vaginalis cyclin B3, putative 0.0087 0.0071 0.0244
Loa Loa (eye worm) hypothetical protein 0.006 0.0041 0.0047
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0036 0.0041
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0011 0.0031
Echinococcus granulosus leukotriene A 4 hydrolase 0.006 0.0041 0.004
Schistosoma mansoni amine GPCR 0.0925 0.1048 0.1047
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0093 0.0079 0.0078
Toxoplasma gondii hypothetical protein 0.0066 0.0047 0.0158
Echinococcus granulosus nmda type glutamate receptor 0.0249 0.026 0.0259
Echinococcus multilocularis GPCR, family 2 0.0671 0.0752 0.0751
Brugia malayi Endoplasmin precursor 0.0136 0.0129 0.0156
Brugia malayi heat shock protein 90 0.0136 0.0129 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0108 0.0375
Trypanosoma brucei Heat shock protein 83, putative 0.0136 0.0129 0.1091
Brugia malayi Cyclin, N-terminal domain containing protein 0.0181 0.0181 0.022
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Loa Loa (eye worm) hypothetical protein 0.0089 0.0074 0.0087
Echinococcus multilocularis Tubulin beta 2C chain 0.0225 0.0232 0.0231
Giardia lamblia Neurogenic locus notch-like protein 0.0132 0.0124 0.1006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0079 0.0271
Loa Loa (eye worm) latrophilin receptor protein 2 0.0671 0.0752 0.0916
Giardia lamblia Beta tubulin 0.0225 0.0232 0.1939
Plasmodium falciparum membrane associated erythrocyte binding-like protein 0.0066 0.0047 0.0159
Brugia malayi hypothetical protein 0.1086 0.1236 0.1509
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0036 0.1183
Plasmodium falciparum glutathione reductase 0.0062 0.0043 0.0143
Toxoplasma gondii beta tubulin 0.0225 0.0232 0.0814
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0005 0.0004
Echinococcus granulosus c4b binding protein beta chain 0.0047 0.0026 0.0024
Onchocerca volvulus 0.0201 0.0205 0.1681
Mycobacterium ulcerans heat shock protein 90 0.0116 0.0105 0.0342
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0925 0.1048 0.1047
Schistosoma mansoni hypothetical protein 0.0671 0.0752 0.0751
Entamoeba histolytica cyclin family protein 0.0087 0.0071 0.3031
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0126 0.0118 0.0117
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0062 0.0043 0.014
Loa Loa (eye worm) hypothetical protein 0.0054 0.0033 0.0037
Plasmodium falciparum subtilisin-like protease 2 0.0118 0.0108 0.0375
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0043 0.0292
Leishmania major beta tubulin 0.0225 0.0232 1
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.2451 0.2827 0.2826
Toxoplasma gondii aminopeptidase N, putative 0.006 0.0041 0.0136
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0063 0.0044 0.0142
Entamoeba histolytica hypothetical protein 0.0034 0.001 0.0383
Trypanosoma brucei heat shock protein, putative 0.0136 0.0129 0.1091
Echinococcus multilocularis protein will die slowly 0.0201 0.0205 0.0204
Echinococcus multilocularis rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0654 0.0733 0.2586
Giardia lamblia Tenascin-like 0.0132 0.0124 0.1006
Onchocerca volvulus 0.0925 0.1048 0.8677
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Onchocerca volvulus 0.0172 0.0171 0.1397
Plasmodium vivax apical sushi protein, putative 0.0047 0.0026 0.0082
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0536 0.0595 0.2097
Echinococcus multilocularis epidermal growth factor receptor 0.016 0.0157 0.0155
Mycobacterium ulcerans lipase LipD 0.0035 0.0011 0.0035
Loa Loa (eye worm) glutamate receptor 0.0034 0.001 0.0009
Echinococcus granulosus endoplasmin 0.0116 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Echinococcus multilocularis thyroid hormone receptor alpha 0.014 0.0133 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0108 0.0375
Schistosoma mansoni tubulin subunit beta 0.0225 0.0232 0.0231
Onchocerca volvulus 0.0447 0.0491 0.4056
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0102 0.009 0.0309
Mycobacterium ulcerans thioesterase TesA 0.0068 0.005 0.0162
Brugia malayi Dopamine receptor protein 2 0.0925 0.1048 0.1279
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0011 0.001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0925 0.1048 0.1047
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0069 0.005 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0536 0.0595 0.2097
Echinococcus multilocularis 0.2234 0.2574 0.2573
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0038 0.0014 0.0016
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0026 0.0082
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.017 0.0169 0.1255
Echinococcus granulosus sex peptide receptor 0.0925 0.1048 0.1047
Loa Loa (eye worm) hypothetical protein 0.0082 0.0066 0.0077
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0134 0.0126 0.0125
Mycobacterium leprae Probable polyketide synthase Pks1 0.0084 0.0069 0.0222
Echinococcus multilocularis glutamate receptor 2 0.0134 0.0126 0.0125
Brugia malayi serine/threonine-protein kinase plk-2 0.0093 0.0079 0.0095
Loa Loa (eye worm) hypothetical protein 0.0277 0.0293 0.0355
Toxoplasma gondii rhoptry neck protein RON9 0.0047 0.0026 0.0082
Schistosoma mansoni biogenic amine (5HT) receptor 0.0925 0.1048 0.1047
Brugia malayi endoprotease bli-4 precursor 0.277 0.3198 0.3907
Echinococcus granulosus G protein coupled receptor 139 0.0925 0.1048 0.1047
Plasmodium falciparum protein kinase 5 0.0047 0.0026 0.0082
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.032 0.0344 0.1118
Echinococcus granulosus heat shock protein 90 0.0116 0.0105 0.0104
Mycobacterium tuberculosis Conserved protein 0.0035 0.0011 0.0036
Brugia malayi Zona pellucida-like domain containing protein 0.0027 0.0002 0.0002
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Leishmania major cathepsin L-like protease 0.0062 0.0043 0.1661
Echinococcus multilocularis g-protein coupled receptor 0.0925 0.1048 0.1047
Echinococcus granulosus biogenic amine 5HT receptor 0.0925 0.1048 0.1047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.016 0.0157 0.0155
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0047 0.0026 0.0028
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.004 0.0017 0.0016
Echinococcus granulosus rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Trichomonas vaginalis conserved hypothetical protein 0.0536 0.0595 0.2097
Schistosoma mansoni hypothetical protein 0.0122 0.0113 0.0112
Schistosoma mansoni cpg binding protein 0.0029 0.0005 0.0003
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.0231 0.0751
Echinococcus granulosus integrin beta 2 0.5196 0.6025 0.6024
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0181 0.0181 0.7759
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0129 0.0121 0.4969
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0002 0.0002
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0118 0.0108 0.0131
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0029 0.0005 0.0004
Schistosoma mansoni glutamate receptor AMPA 0.01 0.0087 0.0086
Onchocerca volvulus 0.0047 0.0026 0.0193
Echinococcus multilocularis cyclin dependent kinase 5 0.0047 0.0026 0.0025
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0925 0.1048 0.1047
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0925 0.1048 0.1047
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.006 0.0041 0.004
Loa Loa (eye worm) TK/EGFR protein kinase 0.0297 0.0317 0.0384
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0038 0.0014 0.0042
Echinococcus granulosus Tubulin beta 2C chain 0.0225 0.0232 0.0231
Giardia lamblia High cysteine membrane protein Group 2 0.1029 0.117 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0925 0.1048 0.1047
Echinococcus granulosus dna repair protein rad51 1 0.0046 0.0024 0.0023
Chlamydia trachomatis cytosol aminopeptidase 0.0102 0.009 0.0644
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Brugia malayi Peptidase family M1 containing protein 0.0337 0.0363 0.0442
Echinococcus granulosus fibrillin 1 0.0132 0.0124 0.0123
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0027 0.0002 0.0001
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0925 0.1048 0.1279
Trypanosoma cruzi Aminopeptidase M1, putative 0.0172 0.0171 0.7226
Brugia malayi neuropeptide F receptor 0.0925 0.1048 0.1279
Trypanosoma cruzi cyclin, putative 0.0181 0.0181 0.7705
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0029 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0034 0.001 0.0009
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0002 0.0002
Trichomonas vaginalis cyclins, putative 0.0181 0.0181 0.0634
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0102 0.009 0.3734
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Echinococcus granulosus beta-adrenergic receptor kinase 0.0095 0.0081 0.008
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0079 0.0271
Plasmodium vivax aspartyl proteinase, putative 0.0607 0.0677 0.2389
Leishmania major trypanothione reductase 0.0062 0.0043 0.1675
Schistosoma mansoni hypothetical protein 0.096 0.1089 0.1088
Loa Loa (eye worm) hypothetical protein 0.0047 0.0026 0.0028
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Loa Loa (eye worm) TK/ROR protein kinase 0.0055 0.0035 0.004
Schistosoma mansoni cyclin B 0.0181 0.0181 0.018
Loa Loa (eye worm) hypothetical protein 0.0036 0.0012 0.0012
Echinococcus multilocularis neuropeptide receptor 0.8608 1 1
Trichomonas vaginalis tubulin beta chain, putative 0.0225 0.0232 0.0814
Schistosoma mansoni hypothetical protein 0.0058 0.0038 0.0037
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0179 0.0179 0.0178
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0029 0.0005 0.0004
Schistosoma mansoni cpg binding protein 0.0031 0.0007 0.0005
Schistosoma mansoni glutamate receptor NMDA 0.0134 0.0126 0.0125
Echinococcus multilocularis dnaJ subfamily B 0.0418 0.0457 0.0456
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0071 0.0244
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.1087 0.1236 0.1508
Echinococcus multilocularis neuropeptide Y receptor 0.0925 0.1048 0.1047
Trichomonas vaginalis conserved hypothetical protein 0.0536 0.0595 0.2097
Giardia lamblia Kinase, CMGC CDK 0.0047 0.0026 0.0162
Trypanosoma cruzi heat shock protein 85, putative 0.0136 0.0129 0.5333
Schistosoma mansoni opsin-like receptor 0.0925 0.1048 0.1047
Trichomonas vaginalis tubulin, putative 0.0225 0.0232 0.0814
Echinococcus multilocularis cyclins 0.0087 0.0071 0.007
Toxoplasma gondii subtilisin SUB7 0.0118 0.0108 0.0375
Echinococcus granulosus hypothetical protein 0.0925 0.1048 0.1047
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0036 0.0253
Loa Loa (eye worm) thioredoxin reductase 0.0062 0.0043 0.0049
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Trichomonas vaginalis conserved hypothetical protein 0.0536 0.0595 0.2097
Onchocerca volvulus 0.0047 0.0026 0.0193
Onchocerca volvulus 0.0925 0.1048 0.8677
Brugia malayi Will die slowly protein 0.0201 0.0205 0.0249
Onchocerca volvulus 0.0132 0.0124 0.1008
Toxoplasma gondii Hsp90 domain-containing protein 0.004 0.0017 0.0052
Trypanosoma cruzi DNA repair protein RAD51, putative 0.0046 0.0024 0.064
Echinococcus multilocularis Furin 1 0.0654 0.0733 0.0732
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0134 0.0126 0.0125
Giardia lamblia Beta tubulin 0.0225 0.0232 0.1939
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0084 0.0069 0.0222
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0036 0.012
Loa Loa (eye worm) tubulin beta-4 chain 0.0225 0.0232 0.0281
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0011 0.001
Schistosoma mansoni tubulin subunit beta 0.0225 0.0232 0.0231
Mycobacterium ulcerans Holliday junction DNA helicase RuvA 0.0031 0.0007 0.0021
Echinococcus multilocularis sex peptide receptor 0.0925 0.1048 0.1047
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0011 0.0036
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Schistosoma mansoni metabotropic glutamate receptor 0.0034 0.001 0.0009
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0011 0.0036
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0084 0.0069 0.0222
Loa Loa (eye worm) hypothetical protein 0.0132 0.0124 0.0148
Echinococcus granulosus receptor type guanylyl cyclase 0.0036 0.0012 0.0011
Trichomonas vaginalis cyclin B, putative 0.0087 0.0071 0.0244
Brugia malayi hypothetical protein 0.0047 0.0026 0.003
Loa Loa (eye worm) G-protein coupled receptor 0.0925 0.1048 0.1278
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0041 0.0019 0.0058
Brugia malayi Subtilase family protein 0.0118 0.0108 0.0131
Brugia malayi TATA binding protein associated factor 0.006 0.0041 0.0048
Trypanosoma cruzi cdc2-related kinase 3 0.0047 0.0026 0.0706
Brugia malayi Thioredoxin reductase 0.0062 0.0043 0.0051
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0274 0.029 0.0353
Echinococcus granulosus g protein coupled receptor 0.0925 0.1048 0.1047
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0005 0.0004
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0129 0.0121 0.1015
Echinococcus granulosus voltage dependent calcium channel subunit 0.0027 0.0002 0.0001
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0011 0.001
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0047 0.0025 0.0081
Trichomonas vaginalis heat shock protein, putative 0.004 0.0017 0.0052
Echinococcus multilocularis carboxylesterase 5A 0.0082 0.0066 0.0065
Onchocerca volvulus 0.0047 0.0026 0.0193
Loa Loa (eye worm) fatty acid synthase 0.0081 0.0065 0.0076
Echinococcus granulosus tm gpcr rhodopsin 0.0925 0.1048 0.1047
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Onchocerca volvulus 0.0193 0.0195 0.1598
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0129 0.0121 0.4969
Schistosoma mansoni memapsin-2 (A01 family) 0.0607 0.0677 0.0676
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0084 0.0069 0.0224
Toxoplasma gondii heat shock protein HSP90 0.0136 0.0129 0.0447
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0172 0.0171 0.0596
Brugia malayi Dopamine receptor 0.0925 0.1048 0.1279
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0036 0.012
Echinococcus multilocularis integrin alpha ps 0.0272 0.0287 0.0286
Schistosoma mansoni neuropeptide f receptor 76f 0.0925 0.1048 0.1047
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0108 0.0375
Brugia malayi angiogenesis inhibito 0.0105 0.0092 0.0111
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Brugia malayi EGF-like domain containing protein 0.0132 0.0124 0.015
Loa Loa (eye worm) hypothetical protein 0.0047 0.0026 0.0028
Plasmodium falciparum membrane associated erythrocyte binding-like protein 0.0066 0.0047 0.0159
Trypanosoma cruzi beta tubulin, putative 0.0225 0.0232 1
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0079 0.0063 0.0203
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0011 0.0036
Echinococcus multilocularis beta tubulin 0.0225 0.0232 0.0231
Onchocerca volvulus 0.0047 0.0026 0.0193
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0043 0.1463
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.018 0.0629
Trichomonas vaginalis conserved hypothetical protein 0.0536 0.0595 0.2097
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.029 0.1019
Trypanosoma brucei beta tubulin 0.0225 0.0232 0.2054
Echinococcus granulosus neuropeptide receptor 0.0925 0.1048 0.1047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0925 0.1048 0.1047
Echinococcus granulosus adam 17 protease 0.0074 0.0057 0.0056
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0118 0.0108 0.442
Mycobacterium ulcerans leucyl aminopeptidase 0.0102 0.009 0.0291
Schistosoma mansoni glutamate receptor kainate 0.01 0.0087 0.0086
Onchocerca volvulus 0.003 0.0005 0.0025
Brugia malayi AKH receptor 0.0925 0.1048 0.1279
Brugia malayi neuropeptide F receptor 0.0925 0.1048 0.1279
Brugia malayi hypothetical protein 0.0047 0.0026 0.003
Plasmodium falciparum plasmepsin IX 0.0857 0.097 0.3424
Echinococcus multilocularis integrin alpha ps 0.013 0.0122 0.0121
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0925 0.1048 0.1047
Trypanosoma cruzi cdc2-related kinase 1 0.0047 0.0026 0.0706
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0036 0.0234
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0043 0.0292
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0058 0.0038 0.0045
Onchocerca volvulus 0.0925 0.1048 0.8677
Echinococcus multilocularis endoplasmin 0.0116 0.0105 0.0104
Brugia malayi beta-lactamase 0.0035 0.0011 0.0012
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0925 0.1048 0.1047
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0925 0.1048 0.1047
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0081 0.008
Plasmodium vivax SET domain protein, putative 0.003 0.0005 0.001
Echinococcus granulosus atrial natriuretic peptide receptor 0.0034 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.005 0.0029 0.0033
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0172 0.0171 0.017
Echinococcus granulosus metabotropic glutamate receptor 5 0.0034 0.001 0.0009
Toxoplasma gondii thioredoxin reductase 0.0062 0.0043 0.0143
Plasmodium falciparum plasmepsin II 0.2451 0.2827 1
Echinococcus granulosus cyclins 0.0087 0.0071 0.007
Schistosoma mansoni heat shock protein 0.0136 0.0129 0.0128
Onchocerca volvulus 0.0054 0.0033 0.0252
Giardia lamblia Kinase, PLK 0.0093 0.0079 0.0618
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Toxoplasma gondii aminopeptidase N protein 0.006 0.0041 0.0136
Echinococcus granulosus glutamate receptor 2 0.0134 0.0126 0.0125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0043 0.0292
Echinococcus granulosus dro:myosuppressin receptor 0.0925 0.1048 0.1047
Schistosoma mansoni hypothetical protein 0.0925 0.1048 0.1047
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0925 0.1048 0.1047
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0069 0.005 0.0049
Echinococcus multilocularis neuropeptide receptor 0.0925 0.1048 0.1047
Loa Loa (eye worm) hypothetical protein 0.0047 0.0026 0.0028
Schistosoma mansoni neuropeptide F-like receptor 0.0925 0.1048 0.1047
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.2451 0.2827 1
Trypanosoma brucei RNA helicase, putative 0.096 0.1089 1
Schistosoma mansoni hypothetical protein 0.0671 0.0752 0.0751
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0654 0.0733 0.2586
Echinococcus multilocularis cyclin b3 0.0087 0.0071 0.007
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Mycobacterium ulcerans polyketide synthase 0.0079 0.0063 0.0203
Trichomonas vaginalis tubulin alpha chain, putative 0.0225 0.0232 0.0814
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0102 0.009 0.073
Mycobacterium ulcerans polyketide synthase Pks9 0.0051 0.003 0.0097
Giardia lamblia Neurogenic locus Notch protein precursor 0.0132 0.0124 0.1006
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.1684 0.1932 0.1931
Echinococcus granulosus heat shock protein 90 0.0136 0.0129 0.0128
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0038 0.0014 0.0193
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.006 0.0041 0.1385
Schistosoma mansoni cathepsin D (A01 family) 0.7152 0.8304 0.8303
Mycobacterium ulcerans hypothetical protein 0.0035 0.0011 0.0035
Trichomonas vaginalis meiosis-specific recA homolog Dmc1 0.0046 0.0024 0.0077
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0607 0.0677 0.0676
Loa Loa (eye worm) tubulin beta-2A chain 0.0225 0.0232 0.0281
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0058 0.0038 0.0037
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0079 0.0062 0.0061
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0033 0.0009 0.0007
Echinococcus multilocularis cyclins 0.0087 0.0071 0.007
Schistosoma mansoni ubiquitin-conjugating enzyme E2 I 0.0051 0.003 0.0029
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0459 0.0505 0.0616
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0095 0.0081 0.008
Trichomonas vaginalis endoplasmin, putative 0.006 0.004 0.0135
Schistosoma mansoni tubulin subunit beta 0.0225 0.0232 0.0231
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Echinococcus multilocularis leukotriene A 4 hydrolase 0.006 0.0041 0.004
Schistosoma mansoni hypothetical protein 0.0054 0.0033 0.0032
Echinococcus multilocularis aminopeptidase N 0.0337 0.0363 0.0362
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0118 0.0108 0.0351
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Brugia malayi celfurPC protein 0.2234 0.2574 0.3144
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0925 0.1048 0.1047
Onchocerca volvulus 0.0047 0.0026 0.0193
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Onchocerca volvulus 0.0607 0.0677 0.5602
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0011 0.0036
Brugia malayi beta-lactamase family protein 0.0035 0.0011 0.0012
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0274 0.029 0.0352
Echinococcus granulosus g protein coupled receptor 0.0925 0.1048 0.1047
Schistosoma mansoni biogenic amine receptor 0.0925 0.1048 0.1047
Plasmodium vivax tubulin beta chain, putative 0.0225 0.0232 0.0814
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0079 0.0271
Mycobacterium leprae Probable Holliday junction DNA helicase component RuvA 0.0031 0.0007 0.0021
Trichomonas vaginalis glutaminase, putative 0.0541 0.0601 0.2119
Onchocerca volvulus 0.0047 0.0026 0.0193
Loa Loa (eye worm) glutamate receptor 1 0.01 0.0087 0.0103
Echinococcus multilocularis tubulin subunit beta 0.0225 0.0232 0.0231
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.006 0.0041 0.0136
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0102 0.009 0.0291
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0607 0.0677 0.0676
Loa Loa (eye worm) neuropeptide F receptor 0.0925 0.1048 0.1278
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Loa Loa (eye worm) hypothetical protein 0.0132 0.0124 0.0148
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0179 0.0179 0.0178
Echinococcus granulosus rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0011 0.0036
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0046 0.0024 0.012
Onchocerca volvulus 0.0077 0.006 0.0476
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0079 0.0078
Echinococcus granulosus beta tubulin 0.0225 0.0232 0.0231
Schistosoma mansoni hypothetical protein 0.1449 0.1659 0.1658
Brugia malayi solute carrier family 40, member 1 0.0193 0.0195 0.0237
Giardia lamblia Grp94/Hsp90 0.0116 0.0105 0.0847
Trypanosoma brucei ubiquitin-conjugating enzyme E2, putative 0.0051 0.003 0.0178
Echinococcus granulosus cyclin b3 0.0087 0.0071 0.007
Leishmania major hypothetical protein, conserved 0.0035 0.0011 0.0281
Brugia malayi DNA repair protein RAD51 homolog 1 0.0046 0.0024 0.0028
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0102 0.009 0.3585
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0038 0.0014 0.0042
Trypanosoma brucei heat shock protein, putative 0.0136 0.0129 0.1091
Plasmodium vivax SUMO-conjugating enzyme UBC9, putative 0.0051 0.003 0.0099
Loa Loa (eye worm) RGC/RGC protein kinase 0.0036 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0536 0.0595 0.2097
Leishmania major beta tubulin 0.0225 0.0232 1
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0029 0.0005 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0011 0.0031
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0079 0.0063 0.0204
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.018 0.0629
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0654 0.0733 0.2586
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0925 0.1048 0.1047
Giardia lamblia Beta tubulin 0.0225 0.0232 0.1939
Echinococcus multilocularis neuropeptide Y receptor 0.0925 0.1048 0.1047
Schistosoma mansoni cyclins 0.0087 0.0071 0.007
Brugia malayi Furin-like cysteine rich region family protein 0.0297 0.0317 0.0386
Schistosoma mansoni myosin xvIII 0.0925 0.1048 0.1047
Onchocerca volvulus 0.0029 0.0005 0.0018
Echinococcus granulosus puromycin sensitive aminopeptidase 0.006 0.0041 0.004
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0079 0.0062 0.0061
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.008 0.0063 0.0206
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0093 0.0079 0.3254
Trichomonas vaginalis cyclins, putative 0.0181 0.0181 0.0634
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0118 0.0108 0.0353
Plasmodium vivax thioredoxin reductase, putative 0.0062 0.0043 0.0143
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Brugia malayi cell division control protein 2 homolog 0.0047 0.0026 0.003
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0085 0.007 0.0069
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0011 0.0031
Trichomonas vaginalis heat shock protein, putative 0.0116 0.0105 0.0365
Giardia lamblia Kinase, CMGC CDK 0.0047 0.0026 0.0162
Loa Loa (eye worm) G-protein coupled receptor 0.0925 0.1048 0.1278
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0116 0.0105 0.0342
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.017 0.0169 0.0547
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0925 0.1048 0.1047
Loa Loa (eye worm) hypothetical protein 0.0047 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Echinococcus granulosus cyclin dependent kinase 0.0047 0.0026 0.0025
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0122 0.0113 0.0112
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.012 0.011 0.0359
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0038 0.0014 0.0013
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0179 0.0179 0.0178
Echinococcus multilocularis dna repair protein rad51 1 0.0046 0.0024 0.0023
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0051 0.003 0.0912
Loa Loa (eye worm) hypothetical protein 0.0476 0.0525 0.0639
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0026 0.0082
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0925 0.1048 0.1047
Brugia malayi hypothetical protein 0.0047 0.0026 0.003
Echinococcus granulosus membrane associated guanylate kinase, WW and PDZ 0.0049 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0074 0.0057 0.0067
Loa Loa (eye worm) hypothetical protein 0.0046 0.0024 0.0026
Brugia malayi EGF-like domain containing protein 0.0132 0.0124 0.015
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0029 0.0005 0.0004
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Leishmania major subtilisin-like serine peptidase 0.0118 0.0108 0.455
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Plasmodium falciparum heat shock protein 90, putative 0.004 0.0017 0.0052
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Onchocerca volvulus 0.0034 0.001 0.0063
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0654 0.0733 0.0732
Trypanosoma cruzi meiotic recombination protein DMC1, putative 0.0046 0.0024 0.064
Brugia malayi ube2i2 protein 0.0051 0.003 0.0036
Schistosoma mansoni tyrosine kinase 0.0036 0.0012 0.0011
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0079 0.0062 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0925 0.1048 0.1047
Schistosoma mansoni tyrosine kinase 0.0158 0.0155 0.0153
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0054 0.0033 0.0107
Echinococcus multilocularis Tubulin beta 2C chain 0.0225 0.0232 0.0231
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0102 0.009 0.0292
Entamoeba histolytica elongation factor-2 kinase, putative 0.0027 0.0002 0.0055
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0116 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0335 0.036 0.0437
Mycobacterium ulcerans 3-dehydroquinate dehydratase 0.2661 0.3071 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0925 0.1048 0.1047
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0029 0.0005 0.0008
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.021 0.0254
Plasmodium falciparum plasmepsin VII 0.0607 0.0677 0.2389
Echinococcus multilocularis ubiquitin conjugating enzyme e2 i 0.0051 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.1449 0.1659 0.2024
Brugia malayi hypothetical protein 0.0607 0.0677 0.0826
Echinococcus granulosus puromycin sensitive aminopeptidase 0.006 0.0041 0.004
Schistosoma mansoni tyrosine kinase 0.016 0.0157 0.0155
Trypanosoma cruzi cyclin 6, putative 0.0181 0.0181 0.7705
Trypanosoma cruzi heat shock protein 85, putative 0.0136 0.0129 0.5333
Echinococcus multilocularis beta tubulin 0.0225 0.0232 0.0231
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0172 0.0171 0.1481
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0925 0.1048 0.1047
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0079 0.0063 0.0204
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0925 0.1048 0.1047
Onchocerca volvulus 0.0047 0.0026 0.0193
Entamoeba histolytica heat shock protein 90, putative 0.0136 0.0129 0.5512
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0038 0.0014 0.0421
Echinococcus multilocularis cyclin B 0.0181 0.0181 0.018
Leishmania major beta tubulin 0.0225 0.0232 1
Brugia malayi Protein kinase domain containing protein 0.0047 0.0026 0.003
Toxoplasma gondii subtilisin SUB6 0.0118 0.0108 0.0375
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0043 0.1463
Brugia malayi Calcitonin receptor-like protein seb-1 0.2119 0.244 0.2981
Entamoeba histolytica aminopeptidase, putative 0.0172 0.0171 0.7332
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Schistosoma mansoni cathepsin D (A01 family) 0.7152 0.8304 0.8303
Trichomonas vaginalis WD repeat domain, putative 0.0201 0.0205 0.0717
Onchocerca volvulus 0.0925 0.1048 0.8677
Mycobacterium ulcerans thioesterase 0.0068 0.005 0.0162
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0038 0.0014 0.0013
Loa Loa (eye worm) melatonin receptor type 1A 0.0925 0.1048 0.1278
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0118 0.0108 0.0107
Schistosoma mansoni integrin alpha 0.0606 0.0677 0.0676
Loa Loa (eye worm) hypothetical protein 0.0447 0.0491 0.0597
Onchocerca volvulus 0.0925 0.1048 0.8677
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0925 0.1048 0.1047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0043 0.0292
Echinococcus multilocularis cyclin dependent kinase 1 0.0047 0.0026 0.0025
Echinococcus granulosus cyclins 0.0087 0.0071 0.007
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.5852 0.679 0.8297
Loa Loa (eye worm) BEN-1 protein 0.0225 0.0232 0.0281
Mycobacterium ulcerans epoxide hydrolase EphA 0.0159 0.0155 0.0504
Trypanosoma cruzi meiotic recombination protein DMC1, putative 0.0046 0.0024 0.064
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0036 0.0263
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0925 0.1048 0.1047
Plasmodium vivax heat shock protein 90, putative 0.004 0.0017 0.0052
Onchocerca volvulus 0.0234 0.0243 0.1996
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0029 0.0005 0.0008
Onchocerca volvulus 0.0925 0.1048 0.8677
Echinococcus granulosus acetylcholinesterase 0.0082 0.0066 0.0065
Onchocerca volvulus 0.0118 0.0108 0.0879
Echinococcus multilocularis dro:myosuppressin receptor 0.0925 0.1048 0.1047
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1853 0.213 0.26
Trypanosoma cruzi heat shock protein, putative 0.004 0.0017 0.0322
Echinococcus multilocularis acetylcholinesterase 0.0082 0.0066 0.0065
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Echinococcus multilocularis allatostatin A receptor 0.1061 0.1207 0.1206
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Brugia malayi follicle stimulating hormone receptor 0.1853 0.213 0.2602
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Echinococcus multilocularis leucine aminopeptidase protein 0.0102 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0055 0.0035 0.0039
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0111 0.01 0.0099
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0034 0.001 0.0009
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0027 0.0768
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0079 0.0063 0.0203
Echinococcus granulosus tubulin beta 1 chain 0.0225 0.0232 0.0231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0043 0.0292
Loa Loa (eye worm) hypothetical protein 0.0095 0.0081 0.0095
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0087 0.0071 0.007
Loa Loa (eye worm) acetylcholinesterase 1 0.0082 0.0066 0.0077
Schistosoma mansoni cyclin B3 0.0087 0.0071 0.007
Echinococcus multilocularis adam 0.0366 0.0397 0.0396
Mycobacterium tuberculosis Polyketide synthase Pks2 0.008 0.0063 0.0206
Entamoeba histolytica cell division protein kinase 2, putative 0.0047 0.0026 0.1062
Trichomonas vaginalis cyclins, putative 0.0115 0.0105 0.0363
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.011 0.0098 0.0119
Brugia malayi AMP-binding enzyme family protein 0.0077 0.006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0079 0.0271
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0038 0.0014 0.0016
Schistosoma mansoni biogenic amine receptor 0.0925 0.1048 0.1047
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0063 0.0044 0.0142
Brugia malayi hypothetical protein 0.0925 0.1048 0.1279
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0038 0.0014 0.0015
Echinococcus multilocularis protein jagged 2 0.0132 0.0124 0.0123
Trypanosoma cruzi heat shock protein 90, putative 0.0116 0.0105 0.4288
Onchocerca volvulus 0.0925 0.1048 0.8677
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0536 0.0595 0.2097
Onchocerca volvulus Serine\/threonine kinase homolog 0.0093 0.0079 0.0634
Leishmania major beta tubulin 0.0225 0.0232 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0925 0.1048 0.1047
Echinococcus granulosus biogenic amine 5HT receptor 0.0925 0.1048 0.1047
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Loa Loa (eye worm) transcription factor SMAD2 0.0088 0.0073 0.0086
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0084 0.0069 0.0224
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.0009
Echinococcus granulosus thioredoxin glutathione reductase 0.0062 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Toxoplasma gondii kringle domain-containing protein 0.0054 0.0033 0.0107
Echinococcus granulosus neuropeptide receptor A26 0.1381 0.158 0.1579
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0036 0.0118
Loa Loa (eye worm) hypothetical protein 0.0043 0.0021 0.0022
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Toxoplasma gondii leucyl aminopeptidase LAP 0.0102 0.009 0.0309
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Giardia lamblia G2/mitotic-specific cyclin B 0.0181 0.0181 0.15
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0234 0.0243 0.0242
Plasmodium vivax plasmepsin V, putative 0.0607 0.0677 0.2389
Loa Loa (eye worm) MH2 domain-containing protein 0.0088 0.0073 0.0086
Loa Loa (eye worm) hypothetical protein 0.0047 0.0026 0.0028
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.006 0.0041 0.1585
Entamoeba histolytica DNA repair protein RAD51, putative 0.0046 0.0024 0.0998
Echinococcus multilocularis nmda type glutamate receptor 0.0249 0.026 0.0259
Schistosoma mansoni c4b-binding protein beta chain 0.0047 0.0026 0.0024
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0051 0.003 0.0097
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0034 0.001 0.0009
Echinococcus multilocularis neuropeptide FF receptor 2 0.0925 0.1048 0.1047
Loa Loa (eye worm) hypothetical protein 0.0181 0.0181 0.0219
Loa Loa (eye worm) hypothetical protein 0.0132 0.0124 0.0148
Trypanosoma cruzi cyclin, putative 0.0181 0.0181 0.7705
Trypanosoma brucei Aminopeptidase M1, putative 0.0172 0.0171 0.1481
Leishmania major beta tubulin 0.0225 0.0232 1
Trypanosoma brucei trypanothione reductase 0.0062 0.0043 0.0295
Brugia malayi Tachykinin-like peptides receptor 99D 0.0925 0.1048 0.1279
Plasmodium vivax heat shock protein, putative 0.004 0.0017 0.0052
Schistosoma mansoni biogenic amine receptor 0.0925 0.1048 0.1047
Echinococcus granulosus disintegrin and metalloproteinase 0.0074 0.0057 0.0056
Brugia malayi hypothetical protein 0.0447 0.0491 0.0599
Loa Loa (eye worm) hypothetical protein 0.0082 0.0066 0.0077
Mycobacterium ulcerans polyketide synthase 0.0084 0.0069 0.0222
Schistosoma mansoni hypothetical protein 0.0671 0.0752 0.0751
Trypanosoma cruzi hypothetical protein, conserved 0.0054 0.0033 0.1024
Toxoplasma gondii subtilisin SUB5 0.0118 0.0108 0.0375
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0118 0.0108 0.0351
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0671 0.0752 0.0916
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0046 0.0024 0.099
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Loa Loa (eye worm) apoptosis regulator protein 0.0058 0.0038 0.0044
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0607 0.0677 0.0676
Brugia malayi hypothetical protein 0.0925 0.1048 0.1279
Loa Loa (eye worm) hypothetical protein 0.0181 0.0181 0.0219
Brugia malayi Receptor family ligand binding region containing protein 0.0034 0.001 0.0011
Echinococcus multilocularis receptor type guanylyl cyclase 0.0036 0.0012 0.0011
Echinococcus granulosus protein arginine methyltransferase 0.0029 0.0005 0.0004
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0003 0.0002
Brugia malayi putative neuropeptide receptor NPR1 0.0925 0.1048 0.1279
Giardia lamblia Tenascin-37 0.0132 0.0124 0.1006
Echinococcus granulosus rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0059 0.0039 0.0127
Echinococcus multilocularis serotonin receptor 0.0925 0.1048 0.1047
Trypanosoma cruzi cdc2-related kinase 1 0.0047 0.0026 0.0706
Brugia malayi Glutamate receptor 1 precursor 0.01 0.0087 0.0105
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Schistosoma mansoni glutamate receptor NMDA 0.0593 0.0661 0.066
Brugia malayi Serotonin receptor 0.0925 0.1048 0.1279
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0728 0.0819 0.0818
Giardia lamblia Tenascin precursor 0.0132 0.0124 0.1006
Echinococcus granulosus orexin receptor type 2 0.0925 0.1048 0.1047
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0051 0.003 0.126
Echinococcus multilocularis rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Toxoplasma gondii DNA repair protein rad10 subfamily protein 0.0031 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0172 0.0171 0.017
Brugia malayi CXXC zinc finger family protein 0.0029 0.0005 0.0004
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0118 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0047 0.0026 0.0028
Mycobacterium tuberculosis Polyketide synthase Pks13 0.012 0.011 0.0359
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.032 0.0344 0.2615
Trypanosoma brucei beta tubulin 0.0225 0.0232 0.2054
Plasmodium vivax subtilisin-like protease 2, putative 0.0118 0.0108 0.0375
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0049 0.0028 0.0027
Toxoplasma gondii aspartyl protease ASP1 0.2451 0.2827 1
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.029 0.1019
Schistosoma mansoni tyrosine kinase 0.016 0.0157 0.0155
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0074 0.0057 0.0056
Brugia malayi EGF-like domain containing protein 0.0132 0.0124 0.015
Schistosoma mansoni protein kinase 0.0126 0.0118 0.0117
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.017 0.0169 0.1286
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0122 0.0113 0.0112
Echinococcus multilocularis Protein lozenge 0.0056 0.0036 0.0035
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0079 0.0062 0.0061
Echinococcus granulosus heat shock protein 0.0136 0.0129 0.0128
Brugia malayi Zona pellucida-like domain containing protein 0.0027 0.0002 0.0002
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0118 0.0108 0.0353
Schistosoma mansoni protein kinase 0.0126 0.0118 0.0117
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0036 0.0228
Loa Loa (eye worm) angiogenesis inhibito 0.0049 0.0028 0.0031
Mycobacterium ulcerans excinuclease ABC subunit C 0.0031 0.0007 0.0021
Loa Loa (eye worm) hypothetical protein 0.003 0.0005 0.0004
Echinococcus granulosus cyclin dependent kinase 5 0.0047 0.0026 0.0025
Brugia malayi Tubulin beta-1 chain 0.0225 0.0232 0.0283
Mycobacterium tuberculosis 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) 0.2661 0.3071 1
Trypanosoma cruzi heat shock protein 90, putative 0.0136 0.0129 0.5333
Trichomonas vaginalis conserved hypothetical protein 0.0536 0.0595 0.2097
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0172 0.0171 0.729
Brugia malayi RE15519p 0.0925 0.1048 0.1279
Echinococcus granulosus cyclins 0.0087 0.0071 0.007
Mycobacterium ulcerans polyketide synthase Pks13 0.012 0.011 0.0357
Leishmania major beta tubulin 0.0225 0.0232 1
Echinococcus multilocularis G protein coupled receptor 139 0.8608 1 1
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0728 0.0819 0.0818
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0079 0.0062 0.0061
Loa Loa (eye worm) tubulin beta chain 0.0225 0.0232 0.0281
Schistosoma mansoni hypothetical protein 0.0536 0.0595 0.0594
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0087 0.0071 0.007
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0079 0.0271
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0116 0.0105 0.4421
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0079 0.3093
Brugia malayi hypothetical protein 0.0925 0.1048 0.1279
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0925 0.1048 0.1047
Loa Loa (eye worm) integrin alpha pat-2 0.0935 0.106 0.1292
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0005 0.0004
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Toxoplasma gondii rhoptry neck protein RON1 0.0047 0.0026 0.0082
Brugia malayi Pre-SET motif family protein 0.0206 0.021 0.0255
Brugia malayi hypothetical protein 0.0046 0.0024 0.0028
Echinococcus multilocularis heat shock protein 90 0.0116 0.0105 0.0104
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0036 0.0117
Trypanosoma cruzi trypanothione reductase, putative 0.0062 0.0043 0.1477
Echinococcus granulosus epidermal growth factor receptor 0.0297 0.0317 0.0316
Schistosoma mansoni hypothetical protein 0.0027 0.0002 0.0001
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0036 0.1388
Toxoplasma gondii subtilisin SUB11 0.0118 0.0108 0.0375
Brugia malayi PDZ domain containing protein 0.005 0.0029 0.0034
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0925 0.1048 0.1047
Trypanosoma brucei Aminopeptidase M1, putative 0.0172 0.0171 0.1481
Trichomonas vaginalis hypothetical protein 0.0536 0.0595 0.2097
Loa Loa (eye worm) hypothetical protein 0.0447 0.0491 0.0597
Trypanosoma cruzi aminopeptidase, putative 0.006 0.0041 0.1385
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0093 0.0079 0.0078
Toxoplasma gondii exonuclease III APE 0.0057 0.0036 0.012
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0034 0.001 0.0009
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0002 0.0002
Trypanosoma cruzi heat shock protein 85, putative 0.0136 0.0129 0.5333
Treponema pallidum Holliday junction DNA helicase (ruvA) 0.0031 0.0007 0.0035
Loa Loa (eye worm) hypothetical protein 0.0111 0.01 0.012
Brugia malayi G protein-coupled receptor F59B2.13 0.0925 0.1048 0.1279
Mycobacterium ulcerans aminopeptidase N PepN 0.006 0.0041 0.0132
Entamoeba histolytica hypothetical protein 0.0027 0.0002 0.0055
Echinococcus granulosus C type lectin domian containing protein 0.0047 0.0026 0.0024
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0607 0.0677 0.0676
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0031
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0047 0.0026 0.0922
Brugia malayi ORL1-like opioid receptor 0.0925 0.1048 0.1279
Echinococcus granulosus rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0925 0.1048 0.1047
Brugia malayi beta-tubulin, identical 0.0225 0.0232 0.0283
Brugia malayi hypothetical protein 0.0925 0.1048 0.1279
Trichomonas vaginalis conserved hypothetical protein 0.0536 0.0595 0.2097
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Giardia lamblia Tenascin-X 0.0132 0.0124 0.1006
Schistosoma mansoni tubulin subunit beta 0.0225 0.0232 0.0231
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0093 0.0079 0.0093
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1136 0.1294 1
Toxoplasma gondii apical membrane antigen AMA1 0.0066 0.0047 0.0159
Plasmodium falciparum M17 leucyl aminopeptidase 0.0102 0.009 0.0309
Leishmania major cathepsin L-like protease 0.0062 0.0043 0.1661
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0225 0.0232 0.0231
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0102 0.009 0.3585
Brugia malayi Carboxylesterase family protein 0.0082 0.0066 0.0079
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Giardia lamblia Hypothetical protein 0.0087 0.0071 0.0553
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Echinococcus multilocularis epidermal growth factor receptor 0.0297 0.0317 0.0316
Trichomonas vaginalis conserved hypothetical protein 0.0536 0.0595 0.2097
Brugia malayi hypothetical protein 0.0925 0.1048 0.1279
Echinococcus multilocularis insulin receptor 0.0095 0.0081 0.008
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0034 0.001 0.0009
Leishmania major beta tubulin 0.0225 0.0232 1
Schistosoma mansoni ap endonuclease 0.0057 0.0036 0.0035
Onchocerca volvulus 0.0035 0.0011 0.0072
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0011 0.0012
Schistosoma mansoni heat shock protein 0.004 0.0017 0.0016
Echinococcus granulosus tyrosine kinase 0.0036 0.0012 0.0011
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0002 0.0002
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0925 0.1048 0.1279
Echinococcus multilocularis C type lectin domian containing protein 0.0047 0.0026 0.0024
Echinococcus granulosus epidermal growth factor receptor 0.016 0.0157 0.0155
Schistosoma mansoni amine GPCR 0.0925 0.1048 0.1047
Brugia malayi GCC2 and GCC3 family protein 0.0057 0.0036 0.0043
Echinococcus multilocularis nmda type glutamate receptor 0.0034 0.001 0.0009
Schistosoma mansoni amine GPCR 0.0925 0.1048 0.1047
Loa Loa (eye worm) beta-lactamase 0.0035 0.0011 0.0011
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0036 0.012
Trypanosoma cruzi subtilisin peptidase 0.0118 0.0108 0.442
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.032 0.0344 0.1208
Loa Loa (eye worm) integrin beta-2 0.7048 0.8183 1
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0011 0.0031
Onchocerca volvulus 0.006 0.0041 0.0319
Schistosoma mansoni hypothetical protein 0.0079 0.0062 0.0061
Loa Loa (eye worm) ube2i2 protein 0.0051 0.003 0.0034
Schistosoma mansoni protein kinase 0.0036 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0011 0.0011
Echinococcus granulosus allatostatin A receptor 0.1061 0.1207 0.1206
Brugia malayi G-protein coupled receptor 0.0925 0.1048 0.1279
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0002 0.0055
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0036 0.1181
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0671 0.0752 0.0751
Trichomonas vaginalis cyclin D, putative 0.0087 0.0071 0.0244
Schistosoma mansoni amine GPCR 0.0925 0.1048 0.1047
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Entamoeba histolytica cyclin, putative 0.0181 0.0181 0.7793
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0079 0.3093
Toxoplasma gondii subtilisin SUB8 0.0118 0.0108 0.0375
Brugia malayi neuroendocrine convertase 1 precursor 0.1741 0.1999 0.2441
Loa Loa (eye worm) neuropeptide F receptor 0.0925 0.1048 0.1278
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0925 0.1048 0.1278
Echinococcus granulosus cyclins 0.0087 0.0071 0.007
Plasmodium falciparum plasmepsin IV 0.2451 0.2827 1
Schistosoma mansoni thyroid hormone receptor 0.014 0.0133 0.0132
Brugia malayi Glutamate receptor 2 precursor 0.01 0.0087 0.0105
Plasmodium falciparum thioredoxin reductase 0.0062 0.0043 0.0143
Plasmodium vivax subtilisin-like serine protease, putative 0.0118 0.0108 0.0375
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0607 0.0677 0.0676
Schistosoma mansoni hypothetical protein 0.0263 0.0276 0.0275
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0126 0.0118 0.0117
Schistosoma mansoni glutamate receptor kainate 0.01 0.0087 0.0086
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0036 0.1521
Mycobacterium tuberculosis Conserved protein 0.0035 0.0011 0.0036
Schistosoma mansoni furin-1 (S08 family) 0.1205 0.1374 0.1373
Echinococcus granulosus Tubulin beta 2C chain 0.0225 0.0232 0.0231
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0026 0.0082
Echinococcus granulosus tm gpcr rhodopsin 0.0925 0.1048 0.1047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0925 0.1048 0.1047
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.006 0.0041 0.0136
Brugia malayi Serotonin receptor 0.0925 0.1048 0.1279
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0084 0.0069 0.0224
Brugia malayi hypothetical protein 0.0234 0.0243 0.0296
Trypanosoma brucei heat shock protein, putative 0.0136 0.0129 0.1091
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0645 0.0722 0.088
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.0009
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0079 0.0063 0.0204
Entamoeba histolytica 90 kDa heat shock protein, putative 0.004 0.0017 0.0692
Brugia malayi hypothetical protein 0.0925 0.1048 0.1279
Echinococcus granulosus tubulin subunit beta 0.0225 0.0232 0.0231
Brugia malayi Immunoglobulin I-set domain containing protein 0.0027 0.0002 0.0002
Onchocerca volvulus 0.0925 0.1048 0.8677
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0053 0.0032 0.0106
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0654 0.0733 0.2586
Brugia malayi hypothetical protein 0.0607 0.0677 0.0826
Echinococcus granulosus 3'partial|membrane associated guanylate kinase ww and pdz 0.0049 0.0028 0.0027
Loa Loa (eye worm) aspartic protease BmAsp-2 0.2451 0.2827 0.3452
Trypanosoma brucei heat shock protein, putative 0.0136 0.0129 0.1091
Trypanosoma brucei heat shock protein 84, putative 0.004 0.0017 0.0056
Brugia malayi Integrin alpha pat-2 precursor 0.0606 0.0677 0.0826
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.0009
Plasmodium vivax protein kinase Crk2 0.0047 0.0026 0.0082
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0118 0.0108 0.0353
Onchocerca volvulus 0.0925 0.1048 0.8677
Loa Loa (eye worm) hypothetical protein 0.0057 0.0036 0.0041
Echinococcus multilocularis thioredoxin glutathione reductase 0.0062 0.0043 0.0042
Trypanosoma cruzi aminopeptidase, putative 0.0172 0.0171 0.7226
Toxoplasma gondii beta-1 tubulin, putative 0.0225 0.0232 0.0814
Trichomonas vaginalis cyclin B, putative 0.0181 0.0181 0.0634
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0102 0.009 0.0644
Echinococcus granulosus serotonin receptor 0.0925 0.1048 0.1047
Loa Loa (eye worm) hypothetical protein 0.0105 0.0092 0.011
Brugia malayi Protein kinase domain containing protein 0.0055 0.0035 0.0041
Plasmodium falciparum plasmepsin III 0.0607 0.0677 0.2389
Trypanosoma brucei mitotic cyclin 6 0.0181 0.0181 0.158
Trichomonas vaginalis tubulin epsilon chain, putative 0.0225 0.0232 0.0814
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Echinococcus granulosus insulin receptor 0.0095 0.0081 0.008
Toxoplasma gondii hypothetical protein 0.0132 0.0124 0.043
Plasmodium vivax heat shock protein 86, putative 0.0136 0.0129 0.0447
Echinococcus granulosus glutamate receptor subunit protein glur 0.0079 0.0062 0.0061
Brugia malayi G-protein coupled receptor 0.0925 0.1048 0.1279
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0079 0.0063 0.0203
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.0816 0.0921 0.2998
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0179 0.0179 0.0178
Echinococcus granulosus acetylcholinesterase 0.0082 0.0066 0.0065
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0095 0.0081 0.008
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0172 0.0171 0.017
Trypanosoma cruzi heat shock protein 90, putative 0.0096 0.0082 0.323
Loa Loa (eye worm) hypothetical protein 0.0925 0.1048 0.1278
Loa Loa (eye worm) kelch domain-containing protein family protein 0.1096 0.1248 0.1522
Brugia malayi Peptidase family M1 containing protein 0.006 0.0041 0.0048
Onchocerca volvulus 0.0047 0.0026 0.0193
Trypanosoma cruzi CYC2-like cyclin, putative 0.0181 0.0181 0.7705
Schistosoma mansoni glutamate receptor AMPA 0.01 0.0087 0.0086
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0079 0.0271
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.4403 0.5101 0.5101
Loa Loa (eye worm) cyclin domain-containing protein 0.0087 0.0071 0.0084
Loa Loa (eye worm) hypothetical protein 0.0165 0.0163 0.0196
Schistosoma mansoni serine-type protease inhibitor 0.4976 0.5769 0.5768
Echinococcus multilocularis Tubulin beta 2C chain 0.0225 0.0232 0.0231
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0026 0.0025
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0654 0.0733 0.2586
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0084 0.0069 0.0222
Schistosoma mansoni tyrosine kinase 0.0297 0.0317 0.0316
Loa Loa (eye worm) endoplasmin 0.0136 0.0129 0.0154
Schistosoma mansoni glutamate receptor kainate 0.01 0.0087 0.0086
Brugia malayi hypothetical protein 0.0047 0.0026 0.003
Echinococcus multilocularis membrane bound transcription factor site 1 0.0118 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.006 0.0041 0.0047
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0134 0.0126 0.0125
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.029 0.1019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0043 0.0292
Loa Loa (eye worm) metalloprotease 0.0049 0.0028 0.0031
Echinococcus multilocularis cyclin B3 1 0.0087 0.0071 0.007
Entamoeba histolytica cyclin family protein 0.0087 0.0071 0.3031
Loa Loa (eye worm) hypothetical protein 0.0058 0.0038 0.0044
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0038 0.0014 0.003
Toxoplasma gondii aspartyl protease 0.0607 0.0677 0.2389
Echinococcus multilocularis neuropeptides capa receptor 0.113 0.1287 0.1286
Schistosoma mansoni apoptosis regulator bax 0.0058 0.0038 0.0037
Onchocerca volvulus 0.0607 0.0677 0.5602
Brugia malayi Disintegrin family protein 0.0074 0.0057 0.0068
Echinococcus multilocularis cyclins 0.0087 0.0071 0.007
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0033 0.0009 0.003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0044 0.0043
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.1684 0.1932 0.1931
Schistosoma mansoni tyrosine kinase 0.0158 0.0155 0.0153
Loa Loa (eye worm) hypothetical protein 0.0047 0.0026 0.0028
Echinococcus granulosus DNA excision repair protein ERCC 1 0.0031 0.0007 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0026 0.0025
Entamoeba histolytica tubulin family protein 0.0225 0.0232 1
Entamoeba histolytica cyclin, putative 0.0087 0.0071 0.3031
Trypanosoma brucei subtilisin peptidase 0.0118 0.0108 0.0902
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0002 0.0002
Schistosoma mansoni endoplasmin 0.0136 0.0129 0.0128
Brugia malayi hypothetical protein 0.0925 0.1048 0.1279
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0046 0.0024 0.0632
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Schistosoma mansoni growth hormone secretagogue receptor 0.0925 0.1048 0.1047
Plasmodium falciparum cysteine repeat modular protein 1 0.0054 0.0033 0.0107
Mycobacterium tuberculosis Conserved protein 0.0035 0.0011 0.0036
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Schistosoma mansoni integrin beta subunit 0.411 0.4759 0.4759
Plasmodium falciparum apical sushi protein 0.0047 0.0026 0.0082
Echinococcus granulosus protein arginine N methyltransferase 8 0.0029 0.0005 0.0004
Schistosoma mansoni tyrosine kinase 0.0158 0.0155 0.0153
Loa Loa (eye worm) proprotein convertase 2 0.0654 0.0733 0.0893
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0607 0.0677 0.0676
Echinococcus granulosus neuropeptides capa receptor 0.113 0.1287 0.1286
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.004 0.0017 0.0016
Brugia malayi proprotein convertase 2 0.1741 0.1999 0.2441
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0036 0.012
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0118 0.0108 0.0375
Loa Loa (eye worm) acyl carrier protein 0.0038 0.0014 0.0015
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0153 0.0148 0.018
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.0009
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0036 0.0012 0.0079
Echinococcus multilocularis disintegrin and metalloproteinase 0.0074 0.0057 0.0056
Leishmania major beta tubulin 0.0225 0.0232 1
Schistosoma mansoni tyrosine kinase 0.0095 0.0081 0.008
Brugia malayi hypothetical protein 0.0925 0.1048 0.1279
Echinococcus granulosus rhodopsin orphan GPCR 0.0925 0.1048 0.1047
Giardia lamblia UBC3 0.0051 0.003 0.0201
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0607 0.0677 0.2389
Schistosoma mansoni hypothetical protein 0.0263 0.0276 0.0275
Loa Loa (eye worm) hypothetical protein 0.006 0.0041 0.0047
Loa Loa (eye worm) BEN-1 protein 0.0225 0.0232 0.0281
Trichomonas vaginalis conserved hypothetical protein 0.0536 0.0595 0.2097
Echinococcus granulosus aminopeptidase N 0.0337 0.0363 0.0362
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0063 0.0044 0.0142
Onchocerca volvulus 0.0047 0.0026 0.0193
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0043 0.1463
Schistosoma mansoni cpg binding protein 0.0031 0.0007 0.0005
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0011 0.0036
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0046 0.0024 0.0632
Loa Loa (eye worm) hypothetical protein 0.277 0.3198 0.3906
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.006 0.0041 0.1385
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0118 0.0108 0.0351
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0051 0.003 0.0099
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0118 0.0108 0.0107
Toxoplasma gondii subtilisin SUB1 0.0118 0.0108 0.0375
Schistosoma mansoni ap endonuclease 0.0057 0.0036 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0536 0.0595 0.2097
Leishmania major heat shock protein 83-1 0.0136 0.0129 0.5442
Trichomonas vaginalis tubulin epsilon chain, putative 0.0225 0.0232 0.0814
Trypanosoma brucei heat shock protein, putative 0.0136 0.0129 0.1091
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.018 0.0629
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0108 0.0375
Schistosoma mansoni site-1 peptidase (S08 family) 0.0118 0.0108 0.0107
Brugia malayi pregnancy-associated plasma protein-A 0.0047 0.0026 0.003
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0005 0.0004
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0118 0.0108 0.0351
Giardia lamblia High cysteine protein 0.0132 0.0124 0.1006
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0191 0.0669
Giardia lamblia Heat shock protein HSP 90-alpha 0.0116 0.0105 0.0847
Mycobacterium ulcerans glutaminase 0.0541 0.0601 0.1956

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) Inhibition of BuChE in rat serum ChEMBL. 17126020
IC50 (binding) 0 Selectivity ratio of IC50 for rat BuChE to rat IC50 for AchE ChEMBL. 17126020
IC50 (binding) 0 Inhibition of BuChE in rat serum ChEMBL. 17126020
IC50 (binding) = 124 nM Inhibition of AChE in rat cortex at pH 5 ChEMBL. 17126020
IC50 (binding) = 124 nM Inhibition of AChE in rat cortex at pH 5 ChEMBL. 17126020

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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