Detailed information for compound 437876

Basic information

Technical information
  • TDR Targets ID: 437876
  • Name: methyl 4-[[[6-cyano-1-[(3-methylimidazol-4-yl )methyl]-3,4-dihydro-2H-quinolin-3-yl]-(methy lsulfonylmethylsulfonyl)amino]methyl]piperidi ne-1-carboxylate
  • MW: 578.704 | Formula: C25H34N6O6S2
  • H donors: 0 H acceptors: 7 LogP: 0.89 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(=O)N1CCC(CC1)CN(S(=O)(=O)CS(=O)(=O)C)C1CN(Cc2cncn2C)c2c(C1)cc(cc2)C#N
  • InChi: 1S/C25H34N6O6S2/c1-28-17-27-13-23(28)16-30-15-22(11-21-10-20(12-26)4-5-24(21)30)31(39(35,36)18-38(3,33)34)14-19-6-8-29(9-7-19)25(32)37-2/h4-5,10,13,17,19,22H,6-9,11,14-16,18H2,1-3H3
  • InChiKey: ZCQGMYIVIJAMQC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-[[[6-cyano-1-[(3-methyl-4-imidazolyl)methyl]-3,4-dihydro-2H-quinolin-3-yl]-(methylsulfonylmethylsulfonyl)amino]methyl]-1-piperidinecarboxylic acid methyl ester
  • 4-[[[6-cyano-1-[(3-methylimidazol-4-yl)methyl]-3,4-dihydro-2H-quinolin-3-yl]-(mesylmethylsulfonyl)amino]methyl]piperidine-1-carboxylic acid methyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0637 0.9221 0.9705
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0105
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.01 0.5
Schistosoma mansoni cpg binding protein 0.003 0.0315 0.0218
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0463 0.0487
Loa Loa (eye worm) hypothetical protein 0.0021 0.0183 0.0193
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0596 0.0501
Brugia malayi steroid hormone receptor 0.004 0.0463 0.0386
Schistosoma mansoni rab6-interacting 0.0039 0.0448 0.0352
Brugia malayi nuclear receptor NHR-88 0.004 0.0463 0.0386
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0463 0.0386
Schistosoma mansoni hypothetical protein 0.0039 0.0448 0.0352
Schistosoma mansoni hypothetical protein 0.0048 0.0578 0.0483
Loa Loa (eye worm) DR-78 0.0019 0.015 0.0157
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0448 0.0448
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0668 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0157
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0463 0.0386
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.015 0.0053
Schistosoma mansoni lipoxygenase 0.0102 0.1369 0.1282
Schistosoma mansoni nuclear hormone receptor 0.004 0.0463 0.0367
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0463 0.0367
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.015 0.015
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0463 0.0463
Brugia malayi Nuclear hormone receptor E75 0.0019 0.015 0.0053
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0463 0.0463
Echinococcus multilocularis RUN 0.0039 0.0448 0.0448
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.015 0.005
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0291 0.0306
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0712 0.0651
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0157
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0173 0.2411 0.2411
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0463 0.0367
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0733 0.064
Brugia malayi nuclear receptor NHR-88 0.0019 0.015 0.0053
Brugia malayi hypothetical protein 0.0039 0.0448 0.0371
Loa Loa (eye worm) hypothetical protein 0.004 0.0463 0.0487
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.015 0.0053
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0733 0.0733
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0463 0.0367
Onchocerca volvulus 0.0039 0.0448 0.0309
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0655 0.0689
Echinococcus granulosus dnaJ subfamily B 0.0409 0.5874 0.5874
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0463 0.0463
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0733 0.0733
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0463 0.0386
Schistosoma mansoni coup transcription factor 0.004 0.0463 0.0367
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0183 0.0193
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0463 0.0487
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0463 0.0487
Brugia malayi nuclear hormone receptor 0.0656 0.9501 1
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0183 0.0089
Schistosoma mansoni nuclear hormone receptor 0.0019 0.015 0.005
Echinococcus granulosus phd:f box containing protein 0.0016 0.01 0.01
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0183 0.0183
Brugia malayi hypothetical protein 0.0019 0.015 0.0053
Echinococcus multilocularis dnaJ subfamily B 0.0409 0.5874 0.5874
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0157
Loa Loa (eye worm) hypothetical protein 0.004 0.0463 0.0487
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0712 0.0712
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0448 0.0472
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0757 0.0664
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.015 0.015
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0712 0.0712
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0463 0.0487
Loa Loa (eye worm) hypothetical protein 0.0021 0.0183 0.0193
Echinococcus granulosus tumor protein p63 0.0338 0.483 0.483
Schistosoma mansoni nuclear receptor 0.0019 0.015 0.005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0712 0.5
Brugia malayi conserved hypotetical protein 0.0019 0.015 0.0053
Echinococcus granulosus RUN 0.0039 0.0448 0.0448
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0463 0.0386
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.01 0.01
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0463 0.0463
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0463 0.0463
Schistosoma mansoni cpg binding protein 0.0029 0.0291 0.0193
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0463 0.0463
Onchocerca volvulus 0.0048 0.0578 0.0443
Brugia malayi hypothetical protein 0.0021 0.0183 0.0089
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0463 0.0487
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0157
Onchocerca volvulus 0.0039 0.0448 0.0309
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0463 0.0463
Onchocerca volvulus 0.0049 0.0596 0.0462
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.01 0.5
Brugia malayi hypothetical protein 0.0039 0.0448 0.0371
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0463 0.0463
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0463 0.0463
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0463 0.0463
Brugia malayi hypothetical protein 0.0021 0.0183 0.0089
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0733 0.0733
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0448 0.0448
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0463 0.0386
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0463 0.0386
Brugia malayi tailless protein 0.0019 0.015 0.0053
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.0757 0.0757
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0463 0.0367
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0463 0.0324
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0463 0.0386
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.015 0.0053
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0463 0.0463
Onchocerca volvulus 0.0029 0.0291 0.0147
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0463 0.0463
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0463 0.0386
Schistosoma mansoni rab6-interacting 0.0039 0.0448 0.0352
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.01 0.0105
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.015 0.015
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.3341 0.3341
Brugia malayi nuclear hormone receptor 0.004 0.0463 0.0386
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0448 0.0448
Echinococcus multilocularis microtubule associated protein 2 0.069 1 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.015 0.015
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0039 0.0448 0.0472
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0448 0.0448
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0463 0.0463
Brugia malayi Doublecortin family protein 0.0039 0.0448 0.0371
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0677 0.9814 1
Brugia malayi hypothetical protein 0.0019 0.015 0.0053
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0463 0.0367
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0057 0.0712 0.0618
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0463 0.0487
Schistosoma mansoni hypothetical protein 0.0409 0.5874 0.5833
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.3341 0.3341
Schistosoma mansoni loxhd1 0.0039 0.0448 0.0352
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.01 0.01
Schistosoma mansoni zinc finger protein 0.0019 0.015 0.005
Loa Loa (eye worm) hypothetical protein 0.004 0.0463 0.0487
Onchocerca volvulus 0.004 0.0463 0.0324
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0183 0.0089
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0157
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0448 1
Schistosoma mansoni nuclear hormone receptor 0.0019 0.015 0.005
Echinococcus granulosus cpg binding protein 0.003 0.0315 0.0315
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0463 0.0367
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0463 0.0386
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0764 0.0671
Brugia malayi CXXC zinc finger family protein 0.0029 0.0291 0.0204
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.01 0.01
Brugia malayi ecdysone receptor 0.0019 0.015 0.0053
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.01 0.0105
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0463 0.0463
Brugia malayi nuclear receptor RXR 0.0019 0.015 0.0053
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0157
Schistosoma mansoni nuclear receptor 0.0019 0.015 0.005
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.015 0.0157
Loa Loa (eye worm) hypothetical protein 0.0049 0.0596 0.0627
Loa Loa (eye worm) hypothetical protein 0.0021 0.0183 0.0193
Brugia malayi hypothetical protein 0.0236 0.3341 0.3448
Loa Loa (eye worm) hypothetical protein 0.004 0.0463 0.0487
Brugia malayi Nuclear hormone receptor E75 0.0019 0.015 0.0053
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.015 0.0053
Brugia malayi jmjC domain containing protein 0.0059 0.0733 0.0674
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0757 0.0664
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0463 0.0386
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.015 0.005
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0463 0.0386
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0463 0.0367
Schistosoma mansoni microtubule-associated protein tau 0.069 1 1
Echinococcus multilocularis cpg binding protein 0.003 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.004 0.0463 0.0487
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.015 0.015
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0757 0.0797
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0448 0.0448
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0157
Brugia malayi jmjC domain containing protein 0.006 0.0757 0.0699
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0157
Schistosoma mansoni cpg binding protein 0.003 0.0315 0.0218
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0463 0.0386
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0157
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0463 0.0386
Brugia malayi nuclear receptor RXR 0.0021 0.0183 0.0089
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0448 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0183 0.0084
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0183 0.0084
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.015 0.015
Schistosoma mansoni lipoxygenase 0.0173 0.2411 0.2335
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0463 0.0487
Schistosoma mansoni thyroid hormone receptor 0.004 0.0463 0.0367
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.015 0.015
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0463 0.0386
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0463 0.0487
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0463 0.0386
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0463 0.0324
Brugia malayi ecdysteroid receptor 0.004 0.0463 0.0386
Loa Loa (eye worm) hypothetical protein 0.004 0.0463 0.0487
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0463 0.0367
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0057 0.0712 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0183 0.0183
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0039 0.0448 0.0472
Schistosoma mansoni survival motor neuron protein 0.0048 0.0578 0.0483
Loa Loa (eye worm) hypothetical protein 0.004 0.0463 0.0487
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.01 0.5
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0124 0.0124
Echinococcus multilocularis tumor protein p63 0.0338 0.483 0.483
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0173 0.2411 0.2411
Loa Loa (eye worm) hypothetical protein 0.004 0.0463 0.0487
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.015 0.0157
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0157
Brugia malayi nuclear receptor NHR-67 0.0019 0.015 0.0053
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0656 0.9501 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0157
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.015 0.015
Schistosoma mansoni thyroid hormone receptor 0.004 0.0463 0.0367
Echinococcus granulosus FTZ F1 alpha 0.004 0.0463 0.0463
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.01 0.01
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0463 0.0463
Loa Loa (eye worm) hypothetical protein 0.0236 0.3341 0.3517
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0105
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0463 0.0367
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.01 0.0105
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0448 0.0448
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0578 0.0508
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0183 0.0193
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0463 0.0463
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.015 0.015
Schistosoma mansoni polycystin 1-related 0.0039 0.0448 0.0352
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0463 0.0463
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0712 0.5
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.015 0.005
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0463 0.0386
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0057 0.0712 0.5
Loa Loa (eye worm) hypothetical protein 0.0021 0.0183 0.0193
Echinococcus multilocularis phd:f box containing protein 0.0016 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0019 0.015 0.0157

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) > 5000 nM Antimalarial activity against Plasmodium falciparum 3D7 ChEMBL. 17722901
ED50 (functional) > 5000 nM Antimalarial activity against Plasmodium falciparum K1 ChEMBL. 17722901
ED50 (functional) > 5000 nM Antimalarial activity against Plasmodium falciparum 3D7 ChEMBL. 17722901
ED50 (functional) > 5000 nM Antimalarial activity against Plasmodium falciparum K1 ChEMBL. 17722901
Inhibition (binding) = 0 % Inhibition of plasmodium falciparum protein farnesyltransferase at 5 nM by scintillation proximity assay ChEMBL. 17722901
Inhibition (binding) = 0 % Inhibition of plasmodium falciparum protein farnesyltransferase at 0.5 nM by scintillation proximity assay ChEMBL. 17722901
Inhibition (binding) = 15 % Inhibition of plasmodium falciparum protein farnesyltransferase at 50 nM by scintillation proximity assay ChEMBL. 17722901

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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