Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | glycogen synthase kinase 3 | 0.0195 | 0.2503 | 0.5 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Giardia lamblia | Kinase, CMGC GSK | 0.0195 | 0.2503 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | cytochrome P450 | 0.016 | 0.1335 | 0.1335 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.016 | 0.1335 | 0.5 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0191 | 0.2353 | 0.1175 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Schistosoma mansoni | biogenic amine receptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0191 | 0.2353 | 0.1965 |
Brugia malayi | glutaminase DH11.1 | 0.0317 | 0.6517 | 0.598 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | neuropeptide receptor | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.2353 | 0.1965 |
Echinococcus granulosus | g protein coupled receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0191 | 0.2353 | 0.8718 |
Brugia malayi | RE15519p | 0.0191 | 0.2353 | 0.1175 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.0195 | 0.2503 | 0.2503 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.016 | 0.1335 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Trypanosoma cruzi | glycogen synthase kinase 3, putative | 0.0195 | 0.2503 | 0.2963 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0279 | 0.5276 | 0.5276 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0191 | 0.2353 | 0.8718 |
Brugia malayi | hypothetical protein | 0.0191 | 0.2353 | 0.1175 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Brugia malayi | G-protein coupled receptor | 0.0191 | 0.2353 | 0.1175 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | opsin-like receptor | 0.0191 | 0.2353 | 0.1965 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Brugia malayi | Cytochrome P450 family protein | 0.0261 | 0.4674 | 0.3854 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Brugia malayi | putative neuropeptide receptor | 0.0191 | 0.2353 | 0.1175 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0191 | 0.2353 | 0.1965 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | hypothetical protein | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Brugia malayi | Serotonin receptor | 0.0191 | 0.2353 | 0.1175 |
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.0195 | 0.2503 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.0195 | 0.2503 | 0.2503 |
Schistosoma mansoni | neuropeptide receptor | 0.0191 | 0.2353 | 0.1965 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.2353 | 0.1965 |
Giardia lamblia | Kinase, CMGC GSK | 0.0195 | 0.2503 | 0.5 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | fmrfamide receptor | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | amine GPCR | 0.0191 | 0.2353 | 0.1965 |
Schistosoma mansoni | amine GPCR | 0.0191 | 0.2353 | 0.1965 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0191 | 0.2353 | 0.8718 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0191 | 0.2353 | 0.1175 |
Brugia malayi | hypothetical protein | 0.0191 | 0.2353 | 0.1175 |
Loa Loa (eye worm) | glutaminase 2 | 0.0317 | 0.6517 | 0.6517 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0191 | 0.2353 | 0.8718 |
Brugia malayi | hypothetical protein | 0.0191 | 0.2353 | 0.1175 |
Brugia malayi | Dopamine receptor protein 1 | 0.0191 | 0.2353 | 0.1175 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | sex peptide receptor | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus multilocularis | allatostatin A receptor | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0191 | 0.2353 | 0.1965 |
Schistosoma mansoni | opsin-like receptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | protein kinase shaggy | 0.0195 | 0.2503 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0191 | 0.2353 | 0.1175 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.016 | 0.1335 | 0.5 |
Echinococcus granulosus | g-protein coupled receptor | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0191 | 0.2353 | 0.1965 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.016 | 0.1335 | 0.5 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | allatostatin A receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | serotonin receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | neuropeptide receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0191 | 0.2353 | 0.8718 |
Brugia malayi | G protein-coupled receptor | 0.0191 | 0.2353 | 0.1175 |
Schistosoma mansoni | biogenic amine receptor | 0.0191 | 0.2353 | 0.1965 |
Leishmania major | cytochrome p450-like protein | 0.0279 | 0.5276 | 1 |
Brugia malayi | hypothetical protein | 0.0191 | 0.2353 | 0.1175 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0191 | 0.2353 | 0.1965 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0191 | 0.2353 | 0.8718 |
Brugia malayi | AKH receptor | 0.0191 | 0.2353 | 0.1175 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0191 | 0.2353 | 0.8718 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0191 | 0.2353 | 0.1175 |
Trypanosoma brucei | cytochrome P450, putative | 0.0279 | 0.5276 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0191 | 0.2353 | 0.8718 |
Brugia malayi | Dopamine receptor | 0.0191 | 0.2353 | 0.1175 |
Brugia malayi | hypothetical protein | 0.0191 | 0.2353 | 0.1175 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0191 | 0.2353 | 0.1175 |
Brugia malayi | G-protein coupled receptor | 0.0191 | 0.2353 | 0.1175 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0279 | 0.5276 | 0.7604 |
Brugia malayi | intracellular kinase | 0.0195 | 0.2503 | 0.1348 |
Schistosoma mansoni | glutaminase | 0.0317 | 0.6517 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0191 | 0.2353 | 0.2353 |
Schistosoma mansoni | amine GPCR | 0.0191 | 0.2353 | 0.1965 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0246 | 0.4198 | 0.7264 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0191 | 0.2353 | 0.1965 |
Brugia malayi | neuropeptide F receptor | 0.0191 | 0.2353 | 0.1175 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0191 | 0.2353 | 0.2353 |
Brugia malayi | hypothetical protein | 0.0191 | 0.2353 | 0.1175 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | g protein coupled receptor | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | neuropeptide receptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus multilocularis | neuropeptide receptor | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Brugia malayi | ORL1-like opioid receptor | 0.0191 | 0.2353 | 0.1175 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0191 | 0.2353 | 0.8718 |
Mycobacterium ulcerans | glutaminase | 0.0317 | 0.6517 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0279 | 0.5276 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0279 | 0.5276 | 0.5276 |
Schistosoma mansoni | neuropeptide receptor | 0.0191 | 0.2353 | 0.1965 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0191 | 0.2353 | 0.2353 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.016 | 0.1335 | 0.5 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | g protein coupled receptor | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0191 | 0.2353 | 0.2353 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.016 | 0.1335 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.0195 | 0.2503 | 0.5 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0191 | 0.2353 | 0.1965 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0191 | 0.2353 | 0.1965 |
Schistosoma mansoni | amine GPCR | 0.0191 | 0.2353 | 0.1965 |
Schistosoma mansoni | biogenic amine receptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Schistosoma mansoni | neuropeptide receptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Echinococcus multilocularis | somatostatin receptor | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.2353 | 0.1965 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0191 | 0.2353 | 0.1965 |
Brugia malayi | Cytochrome P450 family protein | 0.0279 | 0.5276 | 0.4548 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0191 | 0.2353 | 0.8718 |
Brugia malayi | hypothetical protein | 0.0191 | 0.2353 | 0.1175 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0279 | 0.5276 | 0.5276 |
Echinococcus multilocularis | serotonin receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus granulosus | g protein coupled receptor | 0.0191 | 0.2353 | 0.8718 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0195 | 0.2503 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0191 | 0.2353 | 0.1965 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0246 | 0.4198 | 0.7264 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0191 | 0.2353 | 0.1965 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.016 | 0.1335 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.016 | 0.1335 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | somatostatin receptor | 0.0191 | 0.2353 | 0.8718 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.016 | 0.1335 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Brugia malayi | Melatonin receptor type 1A | 0.0191 | 0.2353 | 0.1175 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0191 | 0.2353 | 0.1965 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0191 | 0.2353 | 0.1965 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Echinococcus granulosus | serotonin receptor | 0.0191 | 0.2353 | 0.8718 |
Brugia malayi | Cytochrome P450 family protein | 0.0279 | 0.5276 | 0.4548 |
Echinococcus multilocularis | protein kinase shaggy | 0.0195 | 0.2503 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0195 | 0.2503 | 0.5 |
Brugia malayi | larval opioid receptor | 0.0191 | 0.2353 | 0.1175 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | glutaminase | 0.0317 | 0.6517 | 0.6517 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | g protein coupled receptor | 0.0191 | 0.2353 | 0.8718 |
Trichomonas vaginalis | glutaminase, putative | 0.0317 | 0.6517 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0191 | 0.2353 | 0.1965 |
Brugia malayi | Dopamine receptor protein 2 | 0.0191 | 0.2353 | 0.1175 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0191 | 0.2353 | 0.1965 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0191 | 0.2353 | 0.1965 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0191 | 0.2353 | 0.1965 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.016 | 0.1335 | 0.5 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.016 | 0.1335 | 0.5 |
Echinococcus granulosus | glycogen synthase kinase 3 beta | 0.0195 | 0.2503 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | glycogen synthase kinase 3-related (gsk3) (cmgc group III) | 0.0195 | 0.2503 | 0.2253 |
Brugia malayi | GnHR receptor homolog | 0.0191 | 0.2353 | 0.1175 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0191 | 0.2353 | 0.8718 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.016 | 0.1335 | 0.5 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | amine GPCR | 0.0191 | 0.2353 | 0.1965 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0279 | 0.5276 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0191 | 0.2353 | 0.2353 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | sex peptide receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0191 | 0.2353 | 0.8718 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.016 | 0.1335 | 0.5 |
Echinococcus multilocularis | glycogen synthase kinase 3 beta | 0.0195 | 0.2503 | 1 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.016 | 0.1335 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Brugia malayi | Serotonin receptor | 0.0191 | 0.2353 | 0.1175 |
Schistosoma mansoni | myosin xvIII | 0.0191 | 0.2353 | 0.1965 |
Mycobacterium leprae | putative cytochrome p450 | 0.016 | 0.1335 | 0.5 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0261 | 0.4674 | 0.4674 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0191 | 0.2353 | 0.1965 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.016 | 0.1335 | 0.5 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0191 | 0.2353 | 0.1175 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.2353 | 0.1965 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Trypanosoma brucei | protein kinase, putative | 0.0195 | 0.2503 | 0.2963 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0191 | 0.2353 | 0.2353 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0191 | 0.2353 | 0.2353 |
Schistosoma mansoni | histamine h1 receptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0191 | 0.2353 | 0.8718 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.016 | 0.1335 | 0.5 |
Brugia malayi | sulfakinin receptor protein | 0.0191 | 0.2353 | 0.1175 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0191 | 0.2353 | 0.1175 |
Echinococcus granulosus | neuropeptide s receptor | 0.0191 | 0.2353 | 0.8718 |
Brugia malayi | hypothetical protein | 0.0191 | 0.2353 | 0.1175 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0191 | 0.2353 | 0.8718 |
Leishmania major | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 0.0195 | 0.2503 | 0.2963 |
Echinococcus multilocularis | fmrfamide receptor | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0191 | 0.2353 | 0.1965 |
Mycobacterium leprae | Conserved hypothetical protein | 0.016 | 0.1335 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0195 | 0.2503 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Brugia malayi | hypothetical protein | 0.0191 | 0.2353 | 0.1175 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | adenoreceptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0191 | 0.2353 | 0.8718 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0246 | 0.4198 | 0.7264 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0191 | 0.2353 | 0.1965 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0191 | 0.2353 | 0.1965 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0191 | 0.2353 | 0.8718 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0191 | 0.2353 | 0.1965 |
Schistosoma mansoni | opsin-like receptor | 0.0191 | 0.2353 | 0.1965 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0422 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.016 | 0.1335 | 0.5 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0191 | 0.2353 | 0.8718 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.2353 | 0.2353 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.016 | 0.1335 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.016 | 0.1335 | 0.5 |
Onchocerca volvulus | 0.0195 | 0.2503 | 1 | |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0191 | 0.2353 | 0.1965 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0191 | 0.2353 | 0.2353 |
Brugia malayi | neuropeptide F receptor | 0.0191 | 0.2353 | 0.1175 |
Echinococcus granulosus | neuropeptide receptor | 0.0191 | 0.2353 | 0.8718 |
Echinococcus granulosus | orexin receptor type 2 | 0.0191 | 0.2353 | 0.8718 |
Echinococcus multilocularis | fmrfamide receptor | 0.0191 | 0.2353 | 0.8718 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.016 | 0.1335 | 0.5 |
Brugia malayi | hypothetical protein | 0.0191 | 0.2353 | 0.1175 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0191 | 0.2353 | 0.2353 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0191 | 0.2353 | 0.1175 |
Leishmania major | hypothetical protein, conserved | 0.0246 | 0.4198 | 0.7264 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
HD50 (ADMET) | = 9.7 uM | Cytotoxicity against human erythrocytes assessed as hemolytic activity after 60 mins | ChEMBL. | 17306549 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.