Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0177 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0177 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0177 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0177 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0177 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0177 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0177 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0177 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0177 | 1 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0177 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0177 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0177 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0177 | 1 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0177 | 1 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0177 | 1 | 0.5 |
Onchocerca volvulus | 0.0177 | 1 | 1 | |
Echinococcus granulosus | hypothetical protein | 0.0177 | 1 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0177 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0177 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0177 | 1 | 0.5 |
Plasmodium falciparum | stearoyl-CoA desaturase | 0.0113 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0177 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0177 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0177 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0177 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0177 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0177 | 1 | 1 |
Onchocerca volvulus | 0.0177 | 1 | 1 | |
Loa Loa (eye worm) | oxidoreductase | 0.0177 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0177 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0177 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0177 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0177 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0177 | 1 | 1 |
Onchocerca volvulus | 0.0177 | 1 | 1 | |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0177 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0177 | 1 | 1 |
Onchocerca volvulus | 0.0177 | 1 | 1 | |
Loa Loa (eye worm) | oxidoreductase | 0.0177 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0177 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0177 | 1 | 0.5 |
Onchocerca volvulus | 0.0177 | 1 | 1 | |
Schistosoma mansoni | aldo-keto reductase | 0.0177 | 1 | 0.5 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0142 | 0.4631 | 0.4631 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0177 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0177 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0177 | 1 | 1 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0177 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0177 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0177 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0177 | 1 | 1 |
Plasmodium vivax | stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative | 0.0113 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0177 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0177 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0177 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0177 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0177 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0177 | 1 | 0.5 |
Trypanosoma cruzi | aldo-keto reductase | 0.0177 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0177 | 1 | 0.5 |
Trypanosoma brucei | prostaglandin f synthase | 0.0177 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0177 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0177 | 1 | 0.5 |
Onchocerca volvulus | 0.0177 | 1 | 1 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0177 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0177 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0177 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0177 | 1 | 0.5 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0177 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0177 | 1 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0177 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0177 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0177 | 1 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0177 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0177 | 1 | 0.5 |
Leishmania major | aldo-keto reductase-like protein | 0.0177 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0177 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0177 | 1 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0177 | 1 | 0.5 |
Schistosoma mansoni | pol-related | 0.0177 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0177 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0177 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0177 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 2 % | Parasiticidal activity against Ctenocephalides felis after 24 hrs | ChEMBL. | 17150358 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.