Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.018 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0046 | 0.0612 | 0.0898 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0046 | 0.0612 | 0.0612 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0034 | 0.0123 | 0.018 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0053 | 0.0867 | 0.1274 |
Brugia malayi | Carboxylesterase family protein | 0.0201 | 0.681 | 1 |
Echinococcus multilocularis | mucolipin 3 | 0.0063 | 0.129 | 0.1895 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0034 | 0.0123 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0201 | 0.681 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.681 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0034 | 0.0123 | 0.018 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.1435 | 0.2108 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0182 | 0.6047 | 0.888 |
Echinococcus multilocularis | neuroligin | 0.0034 | 0.0123 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.018 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.533 | 0.533 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0201 | 0.681 | 0.681 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0046 | 0.0612 | 0.0898 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0046 | 0.0612 | 0.0898 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0034 | 0.0123 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0867 | 0.1274 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0034 | 0.0123 | 0.018 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0046 | 0.0612 | 1 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0046 | 0.0612 | 0.0898 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0201 | 0.681 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0034 | 0.0123 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0034 | 0.0123 | 0.018 |
Onchocerca volvulus | 0.0046 | 0.0612 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.2672 | 0.3924 |
Brugia malayi | Coelomocyte uptake defective protein 5 | 0.0063 | 0.129 | 0.1895 |
Echinococcus granulosus | acetylcholinesterase | 0.0201 | 0.681 | 1 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0053 | 0.0867 | 0.1274 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0034 | 0.0123 | 0.018 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0612 | 0.0612 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0612 | 0.0898 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0123 | 0.018 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0053 | 0.0867 | 0.0867 |
Schistosoma mansoni | mucolipin | 0.0063 | 0.129 | 0.129 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0182 | 0.6047 | 0.888 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0123 | 0.018 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0612 | 0.0612 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0034 | 0.0123 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.1435 | 0.2108 |
Loa Loa (eye worm) | carboxylesterase | 0.0034 | 0.0123 | 0.018 |
Schistosoma mansoni | gliotactin | 0.0034 | 0.0123 | 0.0123 |
Echinococcus granulosus | mucolipin 3 | 0.0063 | 0.129 | 0.1895 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0123 | 0.018 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.533 | 0.533 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0123 | 0.018 |
Loa Loa (eye worm) | MBCTL1 | 0.0053 | 0.0867 | 0.1274 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0046 | 0.0612 | 0.0898 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.018 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0201 | 0.681 | 1 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0612 | 0.0898 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0034 | 0.0123 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0123 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.018 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0034 | 0.0123 | 0.5 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0034 | 0.0123 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.018 |
Schistosoma mansoni | mucolipin | 0.0058 | 0.1079 | 0.1079 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.018 |
Loa Loa (eye worm) | carboxylesterase | 0.0201 | 0.681 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0201 | 0.681 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0201 | 0.681 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.681 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0201 | 0.681 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0098 | 0.2672 | 0.3924 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0053 | 0.0867 | 0.1274 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0034 | 0.0123 | 0.0123 |
Echinococcus granulosus | neuroligin | 0.0034 | 0.0123 | 0.018 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0034 | 0.0123 | 0.0123 |
Loa Loa (eye worm) | mucolipin 1 | 0.0063 | 0.129 | 0.1895 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.1435 | 0.1435 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0034 | 0.0123 | 0.0123 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0053 | 0.0867 | 0.1274 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0098 | 0.2672 | 0.3924 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0612 | 0.0898 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0053 | 0.0867 | 0.1274 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0034 | 0.0123 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0123 | 0.018 |
Echinococcus granulosus | carboxylesterase 5A | 0.0201 | 0.681 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0034 | 0.0123 | 0.0123 |
Echinococcus granulosus | geminin | 0.0164 | 0.533 | 0.7826 |
Schistosoma mansoni | acetylcholinesterase | 0.0034 | 0.0123 | 0.0123 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0034 | 0.0123 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0098 | 0.2672 | 0.3924 |
Echinococcus multilocularis | geminin | 0.0164 | 0.533 | 0.7826 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.