Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Bos taurus | Aldose reductase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0071 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0134 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0134 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0134 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0134 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0134 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0134 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1071 | 0.1071 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0134 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0134 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0134 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0134 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0134 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0071 | 0.1071 | 0.1071 |
Brugia malayi | steroid hormone receptor | 0.0134 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0071 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0134 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0134 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0134 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0134 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0134 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0071 | 0.1071 | 0.1071 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0134 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0134 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1071 | 0.1071 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0134 | 1 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0134 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0134 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0134 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0134 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0134 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0071 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1071 | 0.1071 |
Brugia malayi | nuclear hormone receptor | 0.0134 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0134 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0134 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0134 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0134 | 1 | 1 |
Onchocerca volvulus | 0.0134 | 1 | 1 | |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0071 | 0.1071 | 0.1071 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0134 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0071 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0134 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0134 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0134 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0134 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0134 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0134 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0134 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0134 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0134 | 1 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0071 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0134 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0134 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0134 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0134 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0134 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0071 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0134 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0134 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0134 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0134 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0134 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0071 | 0.1071 | 0.1071 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0134 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.