Detailed information for compound 443436

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 466.462 | Formula: C24H23FN4O5
  • H donors: 2 H acceptors: 5 LogP: 0.58 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1ccc(cc1)[C@@H]1CN(C[C@@H]1N)c1nc2n(cc(c(=O)c2cc1F)C(=O)O)C1CC1
  • InChi: 1S/C24H23FN4O5/c1-34-24(33)13-4-2-12(3-5-13)16-9-28(11-19(16)26)22-18(25)8-15-20(30)17(23(31)32)10-29(14-6-7-14)21(15)27-22/h2-5,8,10,14,16,19H,6-7,9,11,26H2,1H3,(H,31,32)/t16-,19-/m0/s1
  • InChiKey: BGCBNMVZAIPJRP-LPHOPBHVSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens dipeptidyl-peptidase 4 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans dipeptidyl aminopeptidase B Get druggable targets OG5_128614 All targets in OG5_128614
Candida albicans dipeptidyl aminopeptidase B Get druggable targets OG5_128614 All targets in OG5_128614
Echinococcus granulosus dipeptidyl aminopeptidaseprotein Get druggable targets OG5_128614 All targets in OG5_128614
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog Get druggable targets OG5_128614 All targets in OG5_128614
Schistosoma japonicum ko:K01278 dipeptidyl-peptidase 4, putative Get druggable targets OG5_128614 All targets in OG5_128614
Loa Loa (eye worm) prolyl oligopeptidase Get druggable targets OG5_128614 All targets in OG5_128614
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) Get druggable targets OG5_128614 All targets in OG5_128614
Brugia malayi prolyl oligopeptidase family protein Get druggable targets OG5_128614 All targets in OG5_128614
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein Get druggable targets OG5_128614 All targets in OG5_128614

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trichomonas vaginalis chromobox protein, putative 0.0073 0.1241 0.1272
Mycobacterium ulcerans hypothetical protein 0.0032 0.0457 0.1683
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Echinococcus granulosus lysine specific demethylase 5A 0.0074 0.1254 0.1238
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Trichomonas vaginalis penicillin-binding protein, putative 0.0032 0.0457 0.0455
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0017 0.0167 0.0149
Entamoeba histolytica acyl-CoA synthetase, putative 0.0021 0.0244 0.0192
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0024 0.0299 0.0318
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0028 0.0385 0.1224
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0457 0.1495
Onchocerca volvulus Dual oxidase homolog 0.0221 0.4064 1
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0028 0.0385 0.1224
Schistosoma mansoni eyes absent homolog 0.0078 0.1333 0.1511
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0025 0.0328 0.0351
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0471 0.8822 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Loa Loa (eye worm) TAR-binding protein 0.0066 0.1108 0.1256
Loa Loa (eye worm) CHromoDomain protein family member 0.0012 0.0079 0.0089
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.015 0.2713 1
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0024 0.0299 0.0339
Loa Loa (eye worm) TATA binding protein associated factor 0.0025 0.0328 0.0372
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0017 0.0167 0.0168
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Plasmodium falciparum acyl-CoA synthetase 0.0015 0.0145 0.032
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0079 0.0062
Onchocerca volvulus 0.0024 0.0299 0.0554
Echinococcus multilocularis beta LACTamase domain containing family member 0.0032 0.0457 0.0497
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.007 0.1191 0.4263
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0017 0.0167 0.019
Loa Loa (eye worm) hypothetical protein 0.0032 0.0457 0.0518
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0033 0.0478 0.0521
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0079 0.0071
Trypanosoma brucei prolyl endopeptidase 0.0017 0.0167 0.0404
Loa Loa (eye worm) hypothetical protein 0.0104 0.1839 0.2084
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0244 0.0899
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0025 0.0328 0.0351
Echinococcus multilocularis tar DNA binding protein 0.0066 0.1108 0.1237
Trichomonas vaginalis hypothetical protein 0.0012 0.0079 0.0062
Toxoplasma gondii prolyl endopeptidase 0.0017 0.0167 0.0404
Giardia lamblia Phosphoglycerate kinase 0.015 0.2713 0.4753
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Schistosoma mansoni hypothetical protein 0.002 0.023 0.0261
Echinococcus multilocularis aminopeptidase N 0.0025 0.0328 0.0351
Trichomonas vaginalis D-aminoacylase, putative 0.0032 0.0457 0.0455
Loa Loa (eye worm) hypothetical protein 0.0015 0.0145 0.0164
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0024 0.0299 0.0665
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Onchocerca volvulus 0.0025 0.0328 0.0625
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0017 0.0167 0.0406
Onchocerca volvulus 0.0032 0.0457 0.0948
Echinococcus granulosus phosphoglycerate kinase 1 0.015 0.2713 0.2699
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0024 0.0299 0.0339
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0017 0.0167 0.0193
Mycobacterium tuberculosis Conserved protein 0.0032 0.0457 0.1228
Echinococcus granulosus CTD small phosphatase protein like 0.0011 0.006 0.0041
Schistosoma mansoni hypothetical protein 0.005 0.08 0.0906
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Onchocerca volvulus 0.0024 0.0299 0.0554
Mycobacterium tuberculosis Probable lipase LipE 0.0032 0.0457 0.1228
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0024 0.0299 0.0665
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Trypanosoma brucei phosphoglycerate kinase 0.0055 0.0902 0.3173
Brugia malayi PHD-finger family protein 0.0061 0.1011 0.2245
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0244 0.0694
Entamoeba histolytica hypothetical protein 0.0012 0.0079 0.002
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0017 0.0167 0.0112
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0061 0.1011 0.1145
Brugia malayi Animal haem peroxidase family protein 0.0221 0.4064 0.9029
Onchocerca volvulus 0.0032 0.0462 0.0962
Schistosoma mansoni chromobox protein 0.0073 0.1241 0.1407
Brugia malayi Protein-tyrosine phosphatase 0.0024 0.0299 0.0665
Onchocerca volvulus Chorion peroxidase homolog 0.0221 0.4064 1
Onchocerca volvulus 0.0024 0.0299 0.0554
Onchocerca volvulus 0.0024 0.0299 0.0554
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0021 0.0244 0.0656
Brugia malayi hypothetical protein 0.0024 0.0299 0.0665
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0129 0.0346
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0012 0.0079 0.006
Brugia malayi PHD-finger family protein 0.002 0.023 0.0511
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0025 0.0328 0.101
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Echinococcus multilocularis phd:f box containing protein 0.002 0.0225 0.0234
Onchocerca volvulus 0.0024 0.0299 0.0554
Onchocerca volvulus 0.0024 0.0299 0.0554
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0244 0.0694
Brugia malayi AF-10 protein 0.002 0.023 0.0511
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.002 0.023 0.0642
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Schistosoma mansoni hypothetical protein 0.0035 0.0526 0.0597
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0024 0.0299 0.0339
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.1056 0.1197
Brugia malayi chromobox protein homolog 3 0.0041 0.063 0.1401
Schistosoma mansoni phd/f-box containing protein 0.002 0.0225 0.0255
Loa Loa (eye worm) hypothetical protein 0.0032 0.0457 0.0518
Entamoeba histolytica hypothetical protein 0.0012 0.0079 0.002
Loa Loa (eye worm) prolyl oligopeptidase 0.0209 0.3836 0.4348
Toxoplasma gondii aminopeptidase N, putative 0.0025 0.0328 0.101
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0024 0.0299 0.0281
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0079 0.0062
Brugia malayi hypothetical protein 0.0078 0.1333 0.2961
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0017 0.0167 0.0616
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0017 0.0167 0.0616
Toxoplasma gondii aminopeptidase N protein 0.0025 0.0328 0.101
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0027 0.037 0.042
Trypanosoma cruzi Aminopeptidase M1, putative 0.0025 0.0328 0.101
Brugia malayi jmjC domain containing protein 0.002 0.0225 0.0501
Trypanosoma cruzi prolyl endopeptidase 0.0017 0.0167 0.0404
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0025 0.0328 0.0372
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0017 0.0167 0.0404
Treponema pallidum exodeoxyribonuclease (exoA) 0.0017 0.0167 0.0264
Onchocerca volvulus 0.0024 0.0299 0.0554
Echinococcus granulosus peregrin 0.0061 0.1011 0.0993
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0024 0.0299 0.025
Brugia malayi Phosphoglycerate kinase 0.0055 0.0902 0.2003
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0079 0.0062
Treponema pallidum phosphoglycerate kinase 0.015 0.2713 0.4791
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0033 0.0478 0.046
Trypanosoma brucei hypothetical protein, conserved 0.0032 0.0457 0.1495
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0457 0.1495
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0225 0.0255
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0012 0.0079 0.0068
Schistosoma mansoni hypothetical protein 0.0011 0.0057 0.0065
Echinococcus multilocularis prolyl endopeptidase 0.0017 0.0167 0.0168
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0164 0.0364
Loa Loa (eye worm) hypothetical protein 0.0012 0.0079 0.0089
Entamoeba histolytica prolyl oligopeptidase family protein 0.0017 0.0167 0.0112
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0025 0.0328 0.101
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0318
Entamoeba histolytica ubiquitin-activating enzyme, putative 0.0013 0.0104 0.0046
Echinococcus multilocularis GPCR, family 2 0.0016 0.0164 0.0164
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0024 0.0299 0.0318
Echinococcus granulosus chromobox protein 2 0.0012 0.0079 0.006
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0017 0.0167 0.0189
Schistosoma mansoni chromobox protein 0.0012 0.0079 0.0089
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Loa Loa (eye worm) jmjC domain-containing protein 0.0126 0.2245 0.2545
Mycobacterium tuberculosis Probable esterase LipL 0.0032 0.0457 0.1228
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0164 0.0145
Plasmodium falciparum heterochromatin protein 1 0.0012 0.0079 0.0071
Loa Loa (eye worm) hypothetical protein 0.0041 0.063 0.0715
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0209 0.3836 0.4348
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0403 0.0399
Entamoeba histolytica hypothetical protein, conserved 0.0017 0.0167 0.0112
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0024 0.0299 0.0903
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0225 0.0255
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0024 0.0299 0.0339
Toxoplasma gondii hypothetical protein 0.0017 0.0167 0.0404
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Echinococcus multilocularis jumonji domain containing 1A 0.002 0.0225 0.0234
Leishmania major hypothetical protein, conserved 0.002 0.0225 0.0624
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0079 0.002
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0025 0.0328 0.0321
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0032 0.0457 0.0518
Echinococcus granulosus jumonji domain containing 1A 0.002 0.0225 0.0207
Trypanosoma brucei phosphoglycerate kinase 0.015 0.2713 1
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0017 0.0167 0.0154
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0024 0.0299 0.0318
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0017 0.0167 0.0404
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0024 0.0299 0.0903
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0025 0.0328 0.101
Mycobacterium ulcerans beta-lactamase 0.0032 0.0457 0.1683
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0079 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0079 0.0062
Loa Loa (eye worm) hypothetical protein 0.0017 0.0167 0.0189
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0024 0.0299 0.0281
Loa Loa (eye worm) beta-lactamase 0.0032 0.0457 0.0518
Onchocerca volvulus 0.0024 0.0299 0.0554
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0079 0.0062
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0024 0.0299 0.0281
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Loa Loa (eye worm) hypothetical protein 0.0025 0.0328 0.0372
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0028 0.0385 0.0436
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0244 0.0542
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0079 0.0062
Loa Loa (eye worm) hypothetical protein 0.0052 0.0839 0.0951
Mycobacterium tuberculosis Conserved protein 0.0032 0.0457 0.1228
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0244 0.0899
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0021 0.0244 0.0899
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0079 0.0175
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0209 0.3836 0.9427
Loa Loa (eye worm) aminopeptidase N 0.0025 0.0328 0.0372
Brugia malayi ThiF family protein 0.0028 0.0385 0.0854
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0024 0.0299 0.0339
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0024 0.0299 0.0318
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0024 0.0299 0.0318
Schistosoma mansoni survival motor neuron protein 0.005 0.08 0.0906
Schistosoma mansoni ferritin light chain 0.0009 0.0019 0.0022
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0079 0.0071
Echinococcus multilocularis 0.0011 0.006 0.0046
Trichomonas vaginalis phosphoglycerate kinase, putative 0.015 0.2713 0.2803
Onchocerca volvulus Peroxidase homolog 0.0221 0.4064 1
Leishmania major tyrosine specific protein phosphatase, putative 0.0024 0.0299 0.0903
Schistosoma mansoni apoferritin-2 0.0009 0.0019 0.0022
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0025 0.0328 0.101
Echinococcus multilocularis Chromo domain 0.0012 0.0079 0.0068
Loa Loa (eye worm) animal heme peroxidase 0.0221 0.4064 0.4607
Brugia malayi jmjC domain containing protein 0.0199 0.3648 0.8105
Entamoeba histolytica acyl-CoA synthetase, putative 0.0021 0.0244 0.0192
Schistosoma mansoni hypothetical protein 0.0353 0.6572 0.7449
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.1011 0.3583
Brugia malayi exodeoxyribonuclease III family protein 0.0017 0.0167 0.0372
Echinococcus multilocularis peroxidasin 0.0221 0.4064 0.4595
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0164 0.0186
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0149 0.268 0.9878
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0281
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.5642 0.585
Schistosoma mansoni hypothetical protein 0.0016 0.0164 0.0186
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0164 0.0164
Onchocerca volvulus 0.0021 0.0244 0.0414
Mycobacterium ulcerans esterase/lipase LipP 0.0032 0.0457 0.1683
Trichomonas vaginalis dullard protein, putative 0.0011 0.006 0.0042
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0025 0.0328 0.101
Schistosoma mansoni chromobox protein 0.0073 0.1241 0.1407
Onchocerca volvulus Prolyl endopeptidase homolog 0.0017 0.0167 0.0222
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0304 0.5642 0.5832
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0471 0.8822 1
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Onchocerca volvulus 0.0025 0.0328 0.0625
Plasmodium vivax heterochromatin protein 1, putative 0.0012 0.0079 0.0071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.5642 0.585
Echinococcus granulosus PHD finger protein rhinoceros 0.0061 0.1011 0.0993
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.5642 0.585
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0225 0.0624
Brugia malayi prolyl oligopeptidase family protein 0.0017 0.0167 0.0371
Loa Loa (eye worm) hypothetical protein 0.0078 0.1333 0.1511
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0514 0.9631 1
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0039 0.0587 0.0666
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0079 0.0089
Loa Loa (eye worm) hypothetical protein 0.002 0.0225 0.0255
Brugia malayi jmjC domain containing protein 0.0074 0.1254 0.2787
Echinococcus multilocularis lysine specific demethylase 6a 0.002 0.0225 0.0234
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0079 0.0062
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0011 0.006 0.0042
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0027 0.037 0.0822
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0079 0.002
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Loa Loa (eye worm) hypothetical protein 0.0025 0.0328 0.0372
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1108 0.1256
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.1056 0.3756
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0024 0.0299 0.0318
Treponema pallidum fructose-bisphosphate aldolase 0.0304 0.5642 1
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0079 0.0175
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0244 0.0899
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.1056 0.1197
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0079 0.0062
Brugia malayi jmjC domain containing protein 0.002 0.0225 0.0501
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.023 0.0642
Mycobacterium tuberculosis Probable hydrolase 0.0032 0.0457 0.1228
Trichomonas vaginalis ap endonuclease, putative 0.0017 0.0167 0.0154
Echinococcus multilocularis JmjC domain containing protein 4 0.002 0.0225 0.0234
Schistosoma mansoni aminopeptidase A (M01 family) 0.0025 0.0328 0.0372
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0025 0.0328 0.101
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0032 0.0457 0.1228
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0281
Leishmania major phosphoglycerate kinase C, glycosomal 0.015 0.2713 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0225 0.0255
Schistosoma mansoni jumonji domain containing protein 0.002 0.0225 0.0255
Trypanosoma cruzi oligopeptidase b 0.0017 0.0167 0.0404
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0839 0.1864
Loa Loa (eye worm) RNA binding protein 0.0066 0.1108 0.1256
Loa Loa (eye worm) animal heme peroxidase 0.0221 0.4064 0.4607
Mycobacterium leprae conserved hypothetical protein 0.0032 0.0457 0.1683
Onchocerca volvulus Peroxidasin homolog 0.0221 0.4064 1
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0025 0.0328 0.0372
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Loa Loa (eye worm) animal heme peroxidase 0.0221 0.4064 0.4607
Trichomonas vaginalis chromobox protein, putative 0.0073 0.1241 0.1272
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.007 0.1191 0.4263
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0032 0.0457 0.1014
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Echinococcus multilocularis hypothetical protein 0.0024 0.0299 0.0318
Loa Loa (eye worm) hypothetical protein 0.0012 0.0079 0.0089
Brugia malayi prolyl oligopeptidase family protein 0.0017 0.0167 0.0371
Echinococcus granulosus geminin 0.0353 0.6572 0.6565
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.023 0.0511
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Mycobacterium ulcerans lipase LipD 0.0032 0.0457 0.1683
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0025 0.0328 0.0372
Brugia malayi hypothetical protein 0.0024 0.0299 0.0665
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0025 0.0328 0.101
Trypanosoma brucei Aminopeptidase M1, putative 0.0025 0.0328 0.101
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0024 0.0299 0.0318
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0017 0.0167 0.0404
Loa Loa (eye worm) hypothetical protein 0.0032 0.0457 0.0518
Toxoplasma gondii phosphoglycerate kinase PGKI 0.015 0.2713 1
Trypanosoma cruzi phosphoglycerate kinase, putative 0.015 0.2713 1
Onchocerca volvulus 0.0024 0.0299 0.0554
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0225 0.0255
Echinococcus multilocularis peregrin 0.0061 0.1011 0.1126
Mycobacterium tuberculosis Probable lipase LipD 0.0032 0.0457 0.1228
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1108 0.1256
Echinococcus granulosus lysine specific demethylase 6a 0.002 0.0225 0.0207
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Brugia malayi jmjC domain containing protein 0.002 0.0225 0.0501
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0079 0.0062
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Loa Loa (eye worm) hypothetical protein 0.0017 0.0167 0.0189
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Onchocerca volvulus 0.0221 0.4064 1
Echinococcus granulosus chromobox protein 1 0.0073 0.1241 0.1225
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0514 0.9631 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0145 0.0164
Trypanosoma cruzi aminopeptidase, putative 0.0025 0.0328 0.101
Schistosoma mansoni hypothetical protein 0.0016 0.0164 0.0186
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Schistosoma mansoni protein tyrosine phosphatase 0.0024 0.0299 0.0339
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0012 0.0079 0.0089
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0199 0.3648 0.4123
Onchocerca volvulus 0.0024 0.0299 0.0554
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0079 0.0062
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0011 0.006 0.0068
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Giardia lamblia PHD finger protein 15 0.0061 0.1011 0.1703
Toxoplasma gondii histone lysine demethylase JMJD6a 0.002 0.0225 0.0624
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0225 0.0207
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0017 0.0167 0.0112
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0021 0.0244 0.0899
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0318
Schistosoma mansoni protein phosphatase 2C 0.002 0.0225 0.0255
Loa Loa (eye worm) animal heme peroxidase 0.0221 0.4064 0.4607
Schistosoma mansoni peroxidasin 0.0221 0.4064 0.4607
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0055 0.0902 0.3173
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0025 0.0328 0.0351
Trichomonas vaginalis chromobox protein, putative 0.0044 0.069 0.0698
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0318
Brugia malayi ThiF family protein 0.0043 0.0662 0.147
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0024 0.0299 0.025
Trichomonas vaginalis molybdopterin biosynthesis moeb protein, putative 0.0013 0.0104 0.0088
Brugia malayi prolyl oligopeptidase family protein 0.007 0.1191 0.2646
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0043 0.0662 0.0644
Loa Loa (eye worm) hypothetical protein 0.0032 0.0457 0.0518
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Loa Loa (eye worm) hypothetical protein 0.0015 0.0145 0.0164
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0011 0.006 0.0133
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0024 0.0299 0.0339
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0167 0.0404
Entamoeba histolytica prolyl oligopeptidase family protein 0.0017 0.0167 0.0112
Leishmania major phosphoglycerate kinase B, cytosolic 0.015 0.2713 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0057 0.0065
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.069 0.1533
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Loa Loa (eye worm) hypothetical protein 0.0032 0.0457 0.0518
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.002 0.0225 0.0624
Trichomonas vaginalis Heterochromatin protein, putative 0.0012 0.0079 0.0062
Schistosoma mansoni ferritin 0.0009 0.0019 0.0022
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0164 0.0364
Loa Loa (eye worm) hypothetical protein 0.0012 0.0079 0.0089
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0764 0.0746
Onchocerca volvulus 0.0024 0.0299 0.0554
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0024 0.0299 0.0903
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0024 0.0299 0.0318
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0017 0.0167 0.0189
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0318
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0025 0.0328 0.101
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.023 0.0642
Onchocerca volvulus 0.0024 0.0299 0.0554
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0024 0.0299 0.0318
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0764 0.0846
Loa Loa (eye worm) hypothetical protein 0.0035 0.0526 0.0597
Echinococcus multilocularis geminin 0.0353 0.6572 0.7443
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0079 0.002
Echinococcus granulosus tar DNA binding protein 0.0066 0.1108 0.1091
Onchocerca volvulus 0.0024 0.0299 0.0554
Onchocerca volvulus Peroxidasin homolog 0.0221 0.4064 1
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0024 0.0299 0.0339
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0079 0.0089
Schistosoma mansoni hypothetical protein 0.0353 0.6572 0.7449
Echinococcus granulosus Dipeptidyl peptidase 9 0.007 0.1191 0.1174
Brugia malayi beta-lactamase 0.0032 0.0457 0.1014
Echinococcus multilocularis chromobox protein 1 0.0073 0.1241 0.1388
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0024 0.0299 0.0281
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Schistosoma mansoni hypothetical protein 0.0061 0.1011 0.1145
Leishmania major oligopeptidase b 0.0017 0.0167 0.0404
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0024 0.0299 0.0339
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0017 0.0167 0.0406
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.1254 0.1422
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0028 0.0385 0.0366
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.1108 0.1256
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.1254 0.1422
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0025 0.0328 0.0309
Toxoplasma gondii phosphoglycerate kinase PGKII 0.015 0.2713 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0764 0.0866
Loa Loa (eye worm) hypothetical protein 0.0012 0.0079 0.0089
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0244 0.0899
Mycobacterium ulcerans hypothetical protein 0.0021 0.0244 0.0899
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0079 0.0071
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.007 0.1191 0.4263
Entamoeba histolytica hypothetical protein 0.0012 0.0079 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.5642 0.585
Brugia malayi TATA binding protein associated factor 0.0025 0.0328 0.0728
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.1241 0.1407
Entamoeba histolytica acyl-coA synthetase, putative 0.0021 0.0244 0.0192
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0024 0.0299 0.0318
Schistosoma mansoni hypothetical protein 0.0016 0.0164 0.0186
Echinococcus granulosus phd:f box containing protein 0.002 0.0225 0.0207
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0025 0.0328 0.101
Schistosoma mansoni hypothetical protein 0.0016 0.0164 0.0186
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0024 0.0299 0.0281
Loa Loa (eye worm) hypothetical protein 0.0078 0.1333 0.1511
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.5642 0.585
Giardia lamblia Protein tyrosine phosphatase 0.0024 0.0299 0.0429
Trypanosoma brucei prolyl oligopeptidase, putative 0.0017 0.0167 0.0404
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Loa Loa (eye worm) PHD-finger family protein 0.0061 0.1011 0.1145
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Loa Loa (eye worm) blistered cuticle protein 3 0.0221 0.4064 0.4607
Brugia malayi Heterochromatin protein 1 0.0073 0.1241 0.2758
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0079 0.0062
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Onchocerca volvulus Peroxidase homolog 0.0221 0.4064 1
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.007 0.1191 0.4263
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0244 0.0899
Brugia malayi prolyl oligopeptidase family protein 0.0017 0.0167 0.0371
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0055 0.0902 0.3173
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0526 0.1169
Schistosoma mansoni phosphoglycerate kinase 0.015 0.2713 0.3075
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0032 0.0457 0.1228
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0015 0.0145 0.0389
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0079 0.0062
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0011 0.006 0.0041
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.007 0.1191 0.4263
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0025 0.0328 0.0309
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Mycobacterium ulcerans phosphoglycerate kinase 0.015 0.2713 1
Trichomonas vaginalis chromobox protein, putative 0.0044 0.069 0.0698
Plasmodium falciparum JmjC domain-containing protein, putative 0.002 0.0225 0.0624
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0318
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.1056 0.3893
Plasmodium vivax ubiquitin activating enzyme, putative 0.0043 0.0662 0.2269
Plasmodium vivax hypothetical protein, conserved 0.002 0.023 0.0642
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0079 0.0068
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Loa Loa (eye worm) hypothetical protein 0.0244 0.4501 0.5102
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.007 0.1191 0.135
Loa Loa (eye worm) hypothetical protein 0.0012 0.0079 0.0089
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0024 0.0299 0.0318
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0025 0.0328 0.0309
Loa Loa (eye worm) hypothetical protein 0.0021 0.0244 0.0276
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0055 0.0902 0.3173
Brugia malayi hypothetical protein 0.0024 0.0299 0.0665
Entamoeba histolytica aminopeptidase, putative 0.0025 0.0328 0.028
Loa Loa (eye worm) hypothetical protein 0.0032 0.0462 0.0524
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0025 0.0328 0.101
Brugia malayi hypothetical protein 0.0244 0.4501 1
Brugia malayi CHD4 protein 0.0012 0.0079 0.0175
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0011 0.006 0.0042
Trichomonas vaginalis phosphoglycerate kinase, putative 0.015 0.2713 0.2803
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0011 0.006 0.0046
Schistosoma mansoni ferritin 0.0009 0.0019 0.0022
Plasmodium falciparum phosphoglycerate kinase 0.015 0.2713 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.1056 0.1039
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0304 0.5642 0.5832
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1108 0.1256
Brugia malayi hypothetical protein 0.0054 0.0875 0.1944
Loa Loa (eye worm) hypothetical protein 0.0021 0.0244 0.0276
Giardia lamblia Ubiquitin-activating enzyme E1 1 0.0013 0.0104 0.0079
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0017 0.0167 0.0406
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0024 0.0299 0.0339
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0025 0.0328 0.0309
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Brugia malayi beta-lactamase family protein 0.0032 0.0457 0.1014
Brugia malayi Bromodomain containing protein 0.0061 0.1011 0.2245
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0032 0.0457 0.1228
Schistosoma mansoni protein tyrosine phosphatase 0.0024 0.0299 0.0339
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.002 0.0225 0.0255
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0079 0.0062
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0024 0.0299 0.0318
Giardia lamblia Alanyl dipeptidyl peptidase 0.0017 0.0167 0.0192
Onchocerca volvulus 0.0221 0.4064 1
Onchocerca volvulus 0.0024 0.0299 0.0554
Echinococcus multilocularis PHD finger protein rhinoceros 0.0061 0.1011 0.1126
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0281
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0017 0.0167 0.0154
Onchocerca volvulus 0.0024 0.0299 0.0554
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0167 0.0404
Trichomonas vaginalis dullard protein, putative 0.0011 0.006 0.0042
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0764 0.0746
Trichomonas vaginalis D-aminoacylase, putative 0.0032 0.0457 0.0455
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0024 0.031 0.0943
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.1056 0.3893
Loa Loa (eye worm) protein tyrosine phosphatase 0.0024 0.0299 0.0339
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0167 0.0154
Trypanosoma brucei aminopeptidase, putative 0.0025 0.0328 0.101
Brugia malayi Protein-tyrosine phosphatase 1 0.0024 0.0299 0.0665
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0457 0.1495
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0079 0.0062
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.002 0.0225 0.0624
Brugia malayi Animal haem peroxidase family protein 0.0221 0.4064 0.9029
Onchocerca volvulus 0.0032 0.0457 0.0948
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0032 0.0457 0.1683
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0028 0.0385 0.1224
Echinococcus granulosus JmjC domain containing protein 4 0.002 0.0225 0.0207
Brugia malayi Animal haem peroxidase family protein 0.0221 0.4064 0.9029
Brugia malayi Peptidase family M1 containing protein 0.0025 0.0328 0.0728
Brugia malayi hypothetical protein 0.0012 0.0079 0.0175
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Loa Loa (eye worm) hypothetical protein 0.002 0.023 0.0261
Onchocerca volvulus 4.1 G protein, putative homolog 0.0024 0.0299 0.0554
Entamoeba histolytica ARF GTPase activating protein, putative 0.0026 0.0347 0.03
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0017 0.0167 0.0404
Echinococcus granulosus Chromo domain 0.0012 0.0079 0.006
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.1056 0.3893
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0017 0.0167 0.0112
Echinococcus multilocularis Dipeptidyl peptidase 9 0.007 0.1191 0.1331
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0129 0.0346
Brugia malayi hypothetical protein 0.0024 0.0299 0.0665
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.1056 0.284
Schistosoma mansoni ferritin 0.0009 0.0019 0.0022
Trypanosoma cruzi ubiquitin-activating enzyme-like protein 0.0013 0.0104 0.0167
Onchocerca volvulus 0.0024 0.0299 0.0554
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0017 0.0167 0.0617
Brugia malayi prolyl oligopeptidase family protein 0.0209 0.3836 0.8522
Schistosoma mansoni ferritin light chain 0.0009 0.0019 0.0022
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0055 0.0902 0.3173
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0764 0.0846
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0025 0.0328 0.0321
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0079 0.0089
Schistosoma mansoni protein tyrosine phosphatase 0.0024 0.0299 0.0339
Loa Loa (eye worm) hypothetical protein 0.0012 0.0079 0.0089
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0024 0.0299 0.0318
Trichomonas vaginalis esterase, putative 0.0032 0.0457 0.0455
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0167 0.0404
Brugia malayi Animal haem peroxidase family protein 0.0221 0.4064 0.9029
Plasmodium vivax JmjC domain containing protein 0.002 0.0225 0.0624
Echinococcus multilocularis chromobox protein 1 0.0073 0.1241 0.1388
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.063 0.1384
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0024 0.0299 0.0339
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0025 0.0328 0.101
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0024 0.0299 0.0339
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.1254 0.1422
Trichomonas vaginalis ap endonuclease, putative 0.0017 0.0167 0.0154
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1108 0.1256
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0011 0.006 0.0042
Echinococcus multilocularis jumonji domain containing protein 0.0085 0.1465 0.1642
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0025 0.0328 0.101
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0079 0.0062
Brugia malayi Peroxidasin 0.0221 0.4064 0.9029
Brugia malayi Peptidase family M1 containing protein 0.0025 0.0328 0.0728
Schistosoma mansoni ap endonuclease 0.0017 0.0167 0.019
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0032 0.0457 0.0518
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0017 0.0167 0.0404
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.5642 0.585
Brugia malayi Peptidase family M1 containing protein 0.0025 0.0328 0.0728
Brugia malayi Animal haem peroxidase family protein 0.0221 0.4064 0.9029
Loa Loa (eye worm) ThiF family protein 0.0028 0.0385 0.0436
Brugia malayi SET domain containing protein 0.0012 0.0079 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0079 0.0062
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0024 0.0299 0.0318
Trypanosoma cruzi phosphoglycerate kinase, putative 0.015 0.2713 1
Echinococcus granulosus Chromobox protein 3 0.0012 0.0079 0.006
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0225 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.063 0.0636
Brugia malayi beta-lactamase family protein 0.0032 0.0457 0.1014
Trypanosoma brucei phosphoglycerate kinase 0.015 0.2713 1
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0024 0.0299 0.025
Mycobacterium ulcerans bacterioferritin BfrA 0.0009 0.0019 0.0071
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0024 0.0299 0.0281
Loa Loa (eye worm) hypothetical protein 0.0054 0.0875 0.0992
Loa Loa (eye worm) prolyl oligopeptidase 0.0017 0.0167 0.0189
Loa Loa (eye worm) hypothetical protein 0.0017 0.0167 0.0189
Echinococcus granulosus GPCR family 2 0.0016 0.0164 0.0145
Brugia malayi TAR-binding protein 0.0066 0.1108 0.2462
Schistosoma mansoni peroxidasin 0.0221 0.4064 0.4607
Loa Loa (eye worm) hypothetical protein 0.015 0.2713 0.3075
Loa Loa (eye worm) hypothetical protein 0.0043 0.0662 0.075
Onchocerca volvulus 0.0024 0.0299 0.0554
Leishmania major ubiquitin-activating enzyme-like protein 0.0028 0.0385 0.1224
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0079 0.0175
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0079 0.0062
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0244 0.0542
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.5642 0.585
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0055 0.0902 0.3173
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0079 0.0062
Loa Loa (eye worm) hypothetical protein 0.0011 0.006 0.0068
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0764 0.0866
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.08 0.1776
Brugia malayi Protein cec-1. 0.0012 0.0079 0.0175
Chlamydia trachomatis phosphoglycerate kinase 0.015 0.2713 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0079 0.0062
Trypanosoma brucei oligopeptidase b 0.0017 0.0167 0.0404
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0.0079 0.0071
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0764 0.0866
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0079 0.0062
Loa Loa (eye worm) hypothetical protein 0.0015 0.0145 0.0164
Brugia malayi hypothetical protein 0.0025 0.0328 0.0728
Schistosoma mansoni ap endonuclease 0.0017 0.0167 0.019
Toxoplasma gondii hypothetical protein 0.0043 0.0662 0.2269
Onchocerca volvulus 0.0025 0.0328 0.0625
Echinococcus granulosus survival motor neuron protein 1 0.0244 0.4501 0.4491
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0024 0.0299 0.0339
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0011 0.006 0.0068
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0017 0.0167 0.0449
Echinococcus granulosus beta LACTamase domain containing family member 0.0032 0.0457 0.0438
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0009 0.0019 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.0457 0.0518
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0079 0.0089
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0024 0.0299 0.0339
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0209 0.3836 0.4336
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0079 0.0071
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0225 0.0624
Loa Loa (eye worm) hypothetical protein 0.0021 0.0244 0.0276
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0079 0.0062
Giardia lamblia Alanyl dipeptidyl peptidase 0.0017 0.0167 0.0192
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.023 0.0642
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0024 0.0299 0.0903
Brugia malayi Protein-tyrosine phosphatase 0.0024 0.0299 0.0665
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0164 0.0164
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0149 0.268 0.9878
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0281
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.5642 0.585
Brugia malayi RNA binding protein 0.0066 0.1108 0.2462
Brugia malayi hypothetical protein 0.0024 0.0299 0.0665
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0017 0.0167 0.0404
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0129 0.0346
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0024 0.0299 0.0339
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.1056 0.1178
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0764 0.1697
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0017 0.0167 0.0189
Echinococcus granulosus aminopeptidase N 0.0025 0.0328 0.0309
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.023 0.0642
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0079 0.0071
Onchocerca volvulus 0.0024 0.0299 0.0554
Mycobacterium ulcerans bacterioferritin BfrB 0.0009 0.0019 0.0071
Loa Loa (eye worm) hypothetical protein 0.0061 0.1011 0.1145
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Onchocerca volvulus 0.0012 0.0079 0.000000035171
Entamoeba histolytica prolyl oligopeptidase family protein 0.0017 0.0167 0.0112
Onchocerca volvulus 0.0024 0.0299 0.0554
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0199 0.3648 0.3636
Trypanosoma cruzi oligopeptidase b 0.0017 0.0167 0.0404
Trypanosoma cruzi aminopeptidase, putative 0.0025 0.0328 0.101
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0318
Schistosoma mansoni apoferritin-2 0.0009 0.0019 0.0022
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Echinococcus multilocularis acylamino acid releasing enzyme 0.0017 0.0167 0.0168
Onchocerca volvulus 0.005 0.08 0.1809
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0025 0.0328 0.0351
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.1056 0.3756
Brugia malayi Blistered cuticle protein 3 0.0221 0.4064 0.9029
Loa Loa (eye worm) hypothetical protein 0.0016 0.0164 0.0186
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0839 0.1864
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0024 0.0299 0.0318
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0244 0.0899
Toxoplasma gondii ABC1 family protein 0.0032 0.0457 0.1495
Echinococcus multilocularis lysine specific demethylase 5A 0.0074 0.1254 0.1403
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0017 0.0167 0.055
Brugia malayi Phosphoglycerate kinase 0.015 0.2713 0.6027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0209 0.3836 0.3824
Brugia malayi hypothetical protein 0.0217 0.3976 0.8832
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0244 0.0694
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0149 0.268 0.7206
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0024 0.0299 0.0339
Schistosoma mansoni ferritin 0.0009 0.0019 0.0022
Trichomonas vaginalis pten, drome, putative 0.0024 0.0299 0.0292
Onchocerca volvulus 0.0024 0.0299 0.0554
Schistosoma mansoni jumonji domain containing protein 0.0158 0.2868 0.3251
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0025 0.0328 0.0309
Mycobacterium ulcerans aminopeptidase N PepN 0.0025 0.0328 0.1208
Brugia malayi hypothetical protein 0.0221 0.4064 0.9029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0079 0.0062
Loa Loa (eye worm) helicase 0.0012 0.0079 0.0089
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0029 0.0411 0.0466
Entamoeba histolytica phosphoglycerate kinase, putative 0.015 0.2713 0.2772
Loa Loa (eye worm) hypothetical protein 0.0025 0.0328 0.0372
Onchocerca volvulus Alhambra homolog 0.0061 0.1011 0.2338
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0281
Leishmania major hypothetical protein, conserved 0.0032 0.0457 0.1495
Trypanosoma brucei phosphoglycerate kinase, putative 0.0055 0.0902 0.3173
Toxoplasma gondii aminopeptidase n, putative 0.0025 0.0328 0.101
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0839 0.0951
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0043 0.0662 0.073
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0164 0.0145
Trichomonas vaginalis D-aminoacylase, putative 0.0032 0.0457 0.0455
Toxoplasma gondii exonuclease III APE 0.0017 0.0167 0.0406
Echinococcus granulosus peroxidasin 0.0221 0.4064 0.4053
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0011 0.006 0.0042
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0025 0.0328 0.101
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0017 0.0167 0.045
Onchocerca volvulus 0.0024 0.0299 0.0554
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0471 0.8822 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Mycobacterium ulcerans aminopeptidase N PepN 0.0025 0.0328 0.1208
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0025 0.0328 0.101
Echinococcus granulosus chromobox protein 1 0.0073 0.1241 0.1225
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0203 0.3719 1
Trypanosoma brucei protein tyrosine phosphatase 1 0.0024 0.0299 0.0903
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Schistosoma mansoni hypothetical protein 0.0012 0.0079 0.0089
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0017 0.0167 0.0406
Brugia malayi hypothetical protein 0.0025 0.0328 0.0728
Brugia malayi jmjC domain containing protein 0.002 0.0225 0.0501
Plasmodium vivax phosphoglycerate kinase, putative 0.015 0.2713 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0281
Schistosoma mansoni chromobox protein 0.0012 0.0079 0.0089
Echinococcus granulosus protein tyrosine phosphatase n9 0.0024 0.0299 0.0281
Schistosoma mansoni dual specificity protein phosphatase 0.0008 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0403 0.0399
Echinococcus multilocularis 0.0024 0.0299 0.0318
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.0079 0.0175
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0079 0.006
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0028 0.0385 0.0415
Echinococcus granulosus jumonji domain containing protein 0.0085 0.1465 0.1448
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0017 0.0167 0.0406
Loa Loa (eye worm) hypothetical protein 0.0024 0.0299 0.0339
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0244 0.0542
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0024 0.0299 0.0339
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0024 0.0299 0.0339
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0024 0.0299 0.0339
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0009 0.0019 0.0071
Plasmodium vivax hypothetical protein, conserved 0.0061 0.1011 0.3583
Trichomonas vaginalis dullard protein, putative 0.0011 0.006 0.0042
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.015 0.2713 0.7295
Echinococcus multilocularis chromobox protein 2 0.0012 0.0079 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.063 0.0636
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.023 0.0261
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0281
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0017 0.0167 0.0404
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0024 0.0299 0.0318
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0024 0.0299 0.0281
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0024 0.0299 0.0281
Loa Loa (eye worm) hypothetical protein 0.0221 0.4064 0.4607
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0012 0.0079 0.0071
Trichomonas vaginalis penicillin-binding protein, putative 0.0032 0.0457 0.0455
Onchocerca volvulus 0.0221 0.4064 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0079 0.0062
Echinococcus multilocularis phosphoglycerate kinase 1 0.015 0.2713 0.306
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0043 0.0662 0.075
Toxoplasma gondii ThiF family protein 0.0028 0.0385 0.1224
Giardia lamblia Fructose-bisphosphate aldolase 0.0304 0.5642 1
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0025 0.0328 0.0309
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0079 0.0062
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0055 0.0902 0.3173
Trypanosoma brucei Aminopeptidase M1, putative 0.0025 0.0328 0.101
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1108 0.1256
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0025 0.0328 0.0351
Loa Loa (eye worm) hypothetical protein 0.0015 0.0145 0.0164
Onchocerca volvulus 0.0032 0.0457 0.0948
Mycobacterium tuberculosis Probable peptidase 0.0017 0.0167 0.0449
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0764 0.0866
Loa Loa (eye worm) hypothetical protein 0.0012 0.0079 0.0089
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.007 0.1191 0.4263
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0009 0.0019 0.0051
Schistosoma mansoni phosphoglycerate kinase 0.015 0.2713 0.3075
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0017 0.0167 0.0406
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.1108 0.2462
Schistosoma mansoni pcd6 interacting protein-related 0.0024 0.0299 0.0339
Plasmodium vivax acyl-CoA synthetase, putative 0.0015 0.0145 0.032
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0024 0.0299 0.0281
Echinococcus multilocularis survival motor neuron protein 1 0.0244 0.4501 0.5091
Plasmodium falciparum phd finger protein, putative 0.0061 0.1011 0.3583
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0032 0.0457 0.0518
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0043 0.0662 0.2269
Echinococcus granulosus acylamino acid releasing enzyme 0.0017 0.0167 0.0148
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.1011 0.3583
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0079 0.0062
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0244 0.0656
Entamoeba histolytica Arf GTPase activating protein, putative 0.0026 0.0347 0.03
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0024 0.0299 0.0339
Mycobacterium leprae Probable lipase LipE 0.0032 0.0457 0.1683
Schistosoma mansoni phosphatidylserine receptor 0.002 0.0225 0.0255
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.015 0.2713 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0244 0.0899
Loa Loa (eye worm) peptidase family M1 containing protein 0.0025 0.0328 0.0372
Echinococcus granulosus leukotriene A 4 hydrolase 0.0471 0.8822 0.882
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0028 0.0385 0.1224
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0025 0.0328 0.0321
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0025 0.0328 0.0351
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0017 0.0167 0.0189
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0015 0.0145 0.0533
Mycobacterium tuberculosis Conserved protein 0.0032 0.0457 0.1228
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0129 0.0346
Plasmodium falciparum peptidase, putative 0.0017 0.0167 0.0404
Echinococcus granulosus prolyl endopeptidase 0.0017 0.0167 0.0148
Onchocerca volvulus 0.0024 0.0299 0.0554
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0024 0.0299 0.0281
Onchocerca volvulus 0.0024 0.0299 0.0554
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0024 0.0299 0.0665

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 3000 nM Inhibition of human recombinant DPP4 ChEMBL. 17822893

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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