Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0013 | 0.0021 | 0.0111 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0059 | 0.0595 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0027 | 0.0199 | 0.0776 |
Brugia malayi | hypothetical protein | 0.0014 | 0.004 | 0.008 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0014 | 0.004 | 0.021 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.007 | 0.0732 | 0.3814 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0086 | 0.0301 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0059 | 0.0595 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0038 | 0.0098 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.0732 | 0.3814 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0059 | 0.0595 | 0.2122 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0027 | 0.0199 | 0.1037 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0217 | 0.085 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0217 | 0.1129 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.019 | 0.0713 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0027 | 0.0199 | 0.1037 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0169 | 0.0622 |
Echinococcus multilocularis | jun protein | 0.0081 | 0.0872 | 0.4547 |
Echinococcus multilocularis | lamin | 0.0026 | 0.019 | 0.099 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0027 | 0.0199 | 0.0654 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0199 | 0.0776 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0355 | 0.1851 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0027 | 0.0199 | 0.075 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0059 | 0.0595 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0027 | 0.0199 | 0.075 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0036 | 0.0313 | 0.5101 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1349 | 0.5623 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0027 | 0.0199 | 0.075 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0027 | 0.0199 | 0.0776 |
Echinococcus granulosus | dna polymerase kappa | 0.0059 | 0.0595 | 0.3102 |
Brugia malayi | aryl hydrocarbon receptor nuclear translocator protein, putative | 0.0018 | 0.0086 | 0.0274 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0182 | 0.0679 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0027 | 0.0199 | 0.0654 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0026 | 0.0182 | 0.0949 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0217 | 0.7912 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0027 | 0.0199 | 0.1037 |
Schistosoma mansoni | DNA polymerase eta | 0.0033 | 0.0273 | 0.1421 |
Onchocerca volvulus | 0.0026 | 0.019 | 0.0621 | |
Onchocerca volvulus | 0.0232 | 0.2736 | 1 | |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0204 | 0.2387 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0225 | 0.0886 |
Trichomonas vaginalis | rotamase, putative | 0.0032 | 0.0258 | 0.0883 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0027 | 0.0199 | 0.075 |
Leishmania major | DNA polymerase eta, putative | 0.0033 | 0.0273 | 0.7605 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0086 | 0.0274 |
Brugia malayi | hypothetical protein | 0.0016 | 0.006 | 0.0164 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0027 | 0.0199 | 0.1037 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0023 | 0.0154 | 0.0561 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0059 | 0.0595 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0028 |
Onchocerca volvulus | Protein cycle homolog | 0.0018 | 0.0086 | 0.0239 |
Leishmania major | DNA polymerase kappa, putative | 0.0039 | 0.0353 | 1 |
Onchocerca volvulus | 0.0026 | 0.0182 | 0.0592 | |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0013 | 0.0021 | 0.0111 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0027 | 0.0199 | 0.1037 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0199 | 0.0776 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0029 | 0.0225 | 0.3589 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0225 | 0.1173 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0014 | 0.004 | 0.0108 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0027 | 0.0199 | 0.075 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0023 | 0.0154 | 0.0499 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0217 | 0.0825 |
Loa Loa (eye worm) | helix-loop-helix DNA-binding domain-containing protein | 0.0018 | 0.0086 | 0.0301 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0027 | 0.0199 | 0.1037 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0059 | 0.0595 | 0.2122 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.0258 | 0.4163 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.1329 | 0.5538 |
Brugia malayi | Helix-loop-helix DNA-binding domain containing protein | 0.0018 | 0.0086 | 0.0274 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0027 | 0.0199 | 0.075 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0027 | 0.0199 | 0.1037 |
Echinococcus granulosus | lamin | 0.0026 | 0.019 | 0.099 |
Schistosoma mansoni | nuclear hormone receptor | 0.0013 | 0.0021 | 0.0111 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0027 | 0.0199 | 0.1037 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0028 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0013 | 0.0021 | 0.0111 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0027 | 0.0199 | 0.0776 |
Brugia malayi | ecdysteroid receptor | 0.0027 | 0.0199 | 0.075 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0033 | 0.0273 | 0.1421 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0059 | 0.0595 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0268 | 0.0918 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0027 | 0.0199 | 0.1037 |
Onchocerca volvulus | 0.0026 | 0.019 | 0.0621 | |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0027 | 0.0199 | 0.075 |
Brugia malayi | nuclear receptor RXR | 0.0014 | 0.004 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0028 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0013 | 0.0021 | 0.0111 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0027 | 0.0199 | 0.075 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0021 | 0.0108 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0033 | 0.0273 | 0.1062 |
Onchocerca volvulus | 0.0064 | 0.0655 | 0.2336 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0086 | 0.0301 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.004 | 0.0108 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0081 | 0.0872 | 0.4547 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0013 | 0.0021 | 0.0111 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0225 | 0.0861 |
Schistosoma mansoni | lamin | 0.0026 | 0.019 | 0.099 |
Brugia malayi | Bromodomain containing protein | 0.0029 | 0.0217 | 0.0825 |
Echinococcus granulosus | peregrin | 0.0029 | 0.0217 | 0.1129 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0027 | 0.0199 | 0.1037 |
Echinococcus granulosus | expressed protein | 0.0033 | 0.0268 | 0.1397 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0225 | 0.8333 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0059 | 0.0595 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0027 | 0.0199 | 0.1037 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 0.139 | 0.7246 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0038 | 0.0071 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0169 | 0.5104 |
Echinococcus granulosus | FTZ F1 alpha | 0.0027 | 0.0199 | 0.1037 |
Echinococcus multilocularis | musashi | 0.0026 | 0.019 | 0.099 |
Schistosoma mansoni | rotamase | 0.0033 | 0.0268 | 0.1397 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0093 | 0.1021 | 0.5323 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0027 | 0.0199 | 0.1037 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0059 | 0.0595 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.0059 | 0.0595 | 0.3102 |
Onchocerca volvulus | 0.0029 | 0.0225 | 0.075 | |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0028 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0013 | 0.0021 | 0.0028 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0093 | 0.1021 | 0.5323 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.019 | 0.0739 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.019 | 0.099 |
Entamoeba histolytica | hypothetical protein | 0.007 | 0.0732 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.019 | 0.0739 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0225 | 0.1173 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0199 | 0.0776 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0059 | 0.0595 | 1 |
Loa Loa (eye worm) | RecQ helicase | 0.0023 | 0.0154 | 0.0587 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0184 | 0.0713 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0029 | 0.0225 | 0.3589 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0027 | 0.0199 | 0.0776 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0027 | 0.0199 | 0.1037 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0199 | 0.0776 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0027 | 0.0199 | 0.1037 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0013 | 0.0021 | 0.0111 |
Brugia malayi | nuclear receptor NHR-88 | 0.0027 | 0.0199 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0028 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0059 | 0.0595 | 1 |
Trypanosoma brucei | unspecified product | 0.0023 | 0.0145 | 0.2202 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0027 | 0.0199 | 0.075 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0033 | 0.0273 | 0.1421 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0013 | 0.0021 | 0.0111 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0013 | 0.0021 | 0.0111 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0013 | 0.0021 | 0.0111 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0027 | 0.0199 | 0.1037 |
Schistosoma mansoni | jumonji domain containing protein | 0.0074 | 0.0783 | 0.4082 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0013 | 0.0021 | 0.0111 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0033 | 0.0273 | 0.1421 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0032 | 0.0258 | 0.7184 |
Echinococcus multilocularis | peregrin | 0.0029 | 0.0217 | 0.1129 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0059 | 0.0595 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0169 | 0.0649 |
Entamoeba histolytica | hypothetical protein | 0.007 | 0.0732 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0212 | 0.1103 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0027 | 0.0199 | 0.075 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0217 | 0.7912 |
Giardia lamblia | DINP protein human, muc B family | 0.0039 | 0.0353 | 1 |
Mycobacterium tuberculosis | Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. | 0.0817 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0469 | 0.1915 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0027 | 0.0199 | 0.1037 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0059 | 0.0595 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0013 | 0.0021 | 0.0111 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.0258 | 0.4163 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0169 | 0.2604 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0033 | 0.0273 | 0.1086 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.019 | 0.099 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0027 | 0.0199 | 0.075 |
Echinococcus granulosus | dna polymerase eta | 0.0033 | 0.0273 | 0.1421 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0217 | 0.1129 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.019 | 0.0713 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0026 | 0.0182 | 0.0949 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0225 | 0.1173 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0059 | 0.0595 | 1 |
Brugia malayi | hypothetical protein | 0.007 | 0.0732 | 0.3002 |
Brugia malayi | Pre-SET motif family protein | 0.0204 | 0.2387 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0291 | 0.1517 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0169 | 0.553 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.1918 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0232 | 0.2736 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0291 | 0.1517 |
Brugia malayi | bZIP transcription factor family protein | 0.0081 | 0.0872 | 0.3596 |
Schistosoma mansoni | thyroid hormone receptor | 0.015 | 0.1726 | 0.8997 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0013 | 0.0021 | 0.0111 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0014 | 0.004 | 0.008 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0123 | 0.139 | 0.7246 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0053 | 0.0515 | 0.8612 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0217 | 0.1129 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0123 | 0.139 | 0.7246 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0026 | 0.0182 | 0.0705 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.007 | 0.0732 | 0.3814 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0028 |
Brugia malayi | steroid hormone receptor | 0.0027 | 0.0199 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.004 | 0.0108 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0059 | 0.0595 | 1 |
Loa Loa (eye worm) | DR-78 | 0.0013 | 0.0021 | 0.0028 |
Schistosoma mansoni | zinc finger protein | 0.0013 | 0.0021 | 0.0111 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0169 | 0.6589 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0059 | 0.0595 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0035 | 0.0291 | 0.1164 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0355 | 0.1851 |
Echinococcus granulosus | jun protein | 0.0081 | 0.0872 | 0.4547 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0032 | 0.0258 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0027 | 0.0199 | 0.1037 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0021 | 0.0108 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0013 | 0.0021 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0028 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0169 | 0.2604 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0027 | 0.0199 | 0.1037 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.019 | 0.099 |
Schistosoma mansoni | thyroid hormone receptor | 0.015 | 0.1726 | 0.8997 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0039 | 0.0353 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0683 | 0.3561 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0199 | 0.0776 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0027 | 0.0199 | 0.0776 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0027 | 0.0199 | 0.075 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0027 | 0.0199 | 0.075 |
Echinococcus granulosus | bloom syndrome protein | 0.0023 | 0.0154 | 0.0803 |
Echinococcus multilocularis | geminin | 0.0166 | 0.1918 | 1 |
Echinococcus granulosus | geminin | 0.0166 | 0.1918 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0027 | 0.0199 | 0.075 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0225 | 0.1173 |
Brugia malayi | hypothetical protein | 0.012 | 0.1349 | 0.5611 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0032 | 0.0258 | 0.4163 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0353 | 0.5794 |
Schistosoma mansoni | lamin | 0.0026 | 0.019 | 0.099 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.015 | 0.1726 | 0.8997 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0027 | 0.0199 | 0.1037 |
Brugia malayi | aryl hydrocarbon receptor AHR-1 | 0.0018 | 0.0086 | 0.0274 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0013 | 0.0021 | 0.0111 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0027 | 0.0199 | 0.1037 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0033 | 0.0273 | 0.1062 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0023 | 0.0154 | 0.0499 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0313 | 0.1255 |
Brugia malayi | polk-prov protein | 0.0036 | 0.0313 | 0.1231 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0033 | 0.0273 | 0.1421 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0086 | 0.0301 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0017 | 0.007 | 0.0627 |
Entamoeba histolytica | hypothetical protein | 0.007 | 0.0732 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.1349 | 0.489 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0025 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0169 | 0.2604 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.019 | 0.099 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.0268 | 0.0918 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.0093 | 0.0484 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0027 | 0.0199 | 0.1037 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0027 | 0.0199 | 0.1037 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0035 | 0.0291 | 0.1517 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0081 | 0.0872 | 0.4547 |
Brugia malayi | jmjC domain containing protein | 0.0093 | 0.1021 | 0.4225 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0225 | 0.1173 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0027 | 0.0199 | 0.0776 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0182 | 0.0705 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.049 | 0.2555 |
Mycobacterium ulcerans | proteasome PrcA | 0.0817 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0027 | 0.0199 | 0.075 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0655 | 0.268 |
Schistosoma mansoni | coup transcription factor | 0.0027 | 0.0199 | 0.1037 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0217 | 0.9488 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0199 | 0.0776 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0028 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0027 | 0.0199 | 0.1037 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0033 | 0.0268 | 0.1042 |
Brugia malayi | jmjC domain containing protein | 0.0035 | 0.0291 | 0.1139 |
Trypanosoma brucei | unspecified product | 0.0053 | 0.0515 | 0.8612 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0014 | 0.004 | 0.008 |
Schistosoma mansoni | jun-related protein | 0.0066 | 0.0683 | 0.3561 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0086 | 0.0301 |
Echinococcus multilocularis | dna polymerase eta | 0.0033 | 0.0273 | 0.1421 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0028 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0039 | 0.0353 | 0.0082 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0036 | 0.0313 | 0.5101 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0028 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0027 | 0.0199 | 0.0654 |
Onchocerca volvulus | 0.0027 | 0.0199 | 0.0654 | |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0217 | 0.1129 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0028 |
Echinococcus multilocularis | bloom syndrome protein | 0.0023 | 0.0154 | 0.0803 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0029 | 0.0225 | 0.3589 |
Entamoeba histolytica | hypothetical protein | 0.007 | 0.0732 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0013 | 0.0021 | 0.0111 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0027 | 0.0199 | 0.0776 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0225 | 0.1173 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0845 | 0.3497 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0217 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0028 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0027 | 0.0199 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0021 | 0.0028 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0013 | 0.0021 | 0.0028 |
Schistosoma mansoni | nuclear hormone receptor | 0.0013 | 0.0021 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0199 | 0.0776 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0014 | 0.004 | 0.021 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.0593 | 0.2437 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0225 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.1918 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.007 | 0.0732 | 0.3814 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0027 | 0.0199 | 0.1037 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0027 | 0.0199 | 0.075 |
Schistosoma mansoni | nuclear receptor | 0.0013 | 0.0021 | 0.0111 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0014 | 0.004 | 0.021 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0027 | 0.0199 | 0.1037 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.004 | 0.0108 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0059 | 0.0595 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.004 | 0.0108 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.019 | 0.0739 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0169 | 0.4495 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0225 | 0.1173 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0033 | 0.0273 | 0.3563 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0169 | 0.5104 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0217 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.004 | 0.0108 |
Echinococcus multilocularis | expressed protein | 0.0033 | 0.0268 | 0.1397 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0027 | 0.0199 | 0.0776 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0217 | 0.085 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0086 | 0.0274 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0291 | 0.1517 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0199 | 0.0776 |
Schistosoma mansoni | aryl hydrocarbon receptor nuclear translocator homolog (darnt) | 0.0018 | 0.0086 | 0.0449 |
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.1349 | 0.489 |
Trypanosoma brucei | unspecified product | 0.0023 | 0.0145 | 0.2202 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1349 | 0.5623 |
Brugia malayi | hypothetical protein | 0.0014 | 0.004 | 0.008 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0013 | 0.0021 | 0.0111 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0014 | 0.004 | 0.021 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0033 | 0.0273 | 0.4406 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0033 | 0.0273 | 0.4406 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0032 | 0.0258 | 0.3366 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0013 | 0.0021 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0273 | 0.1086 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0268 | 0.1067 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0027 | 0.0199 | 0.1037 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Intrinsic activity (functional) | = 0.08 | Relative Intrinsic activity evaluated on [35S]-GTP-gammaS, binding in NIH3T3 cells stably transfected with human Melatonin receptor type 1A | ChEMBL. | 12672242 |
Intrinsic activity (functional) | = 0.42 | Relative Intrinsic activity evaluated on [35S]-GTP-gammaS, binding in NIH3T3 cells stably transfected with human Melatonin receptor type 1B | ChEMBL. | 12672242 |
Intrinsic activity (functional) | = 0.08 | Relative Intrinsic activity evaluated on [35S]-GTP-gammaS, binding in NIH3T3 cells stably transfected with human Melatonin receptor type 1A | ChEMBL. | 12672242 |
Intrinsic activity (functional) | = 0.42 | Relative Intrinsic activity evaluated on [35S]-GTP-gammaS, binding in NIH3T3 cells stably transfected with human Melatonin receptor type 1B | ChEMBL. | 12672242 |
pRA1 (binding) | = -2.69 | Relative Binding Affinity (pRA1) to cloned human Melatonin receptor type 1A, stably expressed in NIH3T3 rat fibroblast cells, determined using 2-[125I]-iodomelatonin | ChEMBL. | 12672242 |
pRA1 (binding) | = -2.69 | Relative Binding Affinity (pRA1) to cloned human Melatonin receptor type 1A, stably expressed in NIH3T3 rat fibroblast cells, determined using 2-[125I]-iodomelatonin | ChEMBL. | 12672242 |
pRA2 (binding) | = -0.85 | Relative Binding Affinity (pRA1) to cloned human Melatonin receptor type 1B, stably expressed in NIH3T3 rat fibroblast cells, determined using 2-[125I]-iodomelatonin | ChEMBL. | 12672242 |
pRA2 (binding) | = -0.85 | Relative Binding Affinity (pRA1) to cloned human Melatonin receptor type 1B, stably expressed in NIH3T3 rat fibroblast cells, determined using 2-[125I]-iodomelatonin | ChEMBL. | 12672242 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.