Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | histone deacetylase 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1235 | 0.5 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0077 | 0.1235 | 0.2067 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0259 | 0.5976 | 0.6229 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0077 | 0.1235 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1235 | 0.5 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0077 | 0.1235 | 0.2067 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0029 | 0 | 0.5 |
Plasmodium falciparum | histone deacetylase 1 | 0.0077 | 0.1235 | 0.5 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0259 | 0.5976 | 1 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0077 | 0.1235 | 0.2067 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0259 | 0.5976 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1235 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0029 | 0 | 0.5 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0077 | 0.1235 | 0.1288 |
Schistosoma mansoni | histone deacetylase | 0.0077 | 0.1235 | 0.1235 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0259 | 0.5976 | 1 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0259 | 0.5976 | 1 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0259 | 0.5976 | 0.5976 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.015 | 0.3135 | 0.3268 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0397 | 0.9594 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1235 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1235 | 0.5 |
Echinococcus granulosus | transcription factor Dp 1 | 0.015 | 0.3135 | 0.3135 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1235 | 0.2067 |
Schistosoma mansoni | histone deacetylase | 0.0077 | 0.1235 | 0.1235 |
Giardia lamblia | Histone deacetylase | 0.0077 | 0.1235 | 0.5 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0259 | 0.5976 | 1 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0259 | 0.5976 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1235 | 0.5 |
Echinococcus granulosus | histone deacetylase 3 | 0.0077 | 0.1235 | 0.1235 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0413 | 1 | 1 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0077 | 0.1235 | 0.2067 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.1235 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.1235 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0077 | 0.1235 | 0.5 |
Echinococcus granulosus | histone deacetylase 1 | 0.0077 | 0.1235 | 0.1235 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0259 | 0.5976 | 0.5976 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0077 | 0.1235 | 0.1288 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.1235 | 0.5 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0259 | 0.5976 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0029 | 0 | 0.5 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0077 | 0.1235 | 0.5 |
Brugia malayi | Histone deacetylase 1 | 0.0077 | 0.1235 | 0.2067 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.