Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | histone deacetylase 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | histone deacetylase 1 | 0.0077 | 0.32 | 0.32 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0077 | 0.32 | 1 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0077 | 0.32 | 0.32 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.32 | 0.5 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0194 | 1 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0077 | 0.32 | 0.32 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0103 | 0.4747 | 0.4747 |
Leishmania major | histone deacetylase, putative | 0.0077 | 0.32 | 0.32 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.32 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.32 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.32 | 0.5 |
Giardia lamblia | Histone deacetylase | 0.0077 | 0.32 | 0.5 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0022 | 0 | 0.5 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0077 | 0.32 | 1 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0077 | 0.32 | 1 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0077 | 0.32 | 0.32 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0077 | 0.32 | 0.32 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0077 | 0.32 | 0.32 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0103 | 0.4747 | 0.4747 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0077 | 0.32 | 0.32 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0194 | 1 | 1 |
Brugia malayi | Histone deacetylase 1 | 0.0077 | 0.32 | 0.32 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0194 | 1 | 1 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0194 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.32 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0077 | 0.32 | 0.32 |
Echinococcus granulosus | histone deacetylase 3 | 0.0077 | 0.32 | 0.32 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.32 | 0.32 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.32 | 0.5 |
Echinococcus granulosus | histone deacetylase 1 | 0.0077 | 0.32 | 0.32 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0112 | 0.525 | 0.525 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.32 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.32 | 0.5 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0194 | 1 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.01 | 0.452 | 0.452 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0194 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0077 | 0.32 | 0.32 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0194 | 1 | 1 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0112 | 0.525 | 0.525 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0194 | 1 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0077 | 0.32 | 0.32 |
Plasmodium falciparum | histone deacetylase 1 | 0.0077 | 0.32 | 1 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0194 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.32 | 0.5 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0077 | 0.32 | 0.32 |
Leishmania major | histone deacetylase, putative | 0.0077 | 0.32 | 0.32 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.