Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | histone deacetylase 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Wolbachia endosymbiont of Brugia malayi | 2-polyprenyl-6-methoxyphenol 4-hydroxylase | 0.0033 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0033 | 0 | 0.5 |
Mycobacterium ulcerans | FAD-linked oxidoreductase | 0.0033 | 0 | 0.5 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0321 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0033 | 0 | 0.5 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0321 | 1 | 1 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0321 | 1 | 1 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0321 | 1 | 1 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0321 | 1 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0077 | 0.1533 | 0.1533 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0321 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 3 | 0.0077 | 0.1533 | 0.1533 |
Mycobacterium leprae | possibleputative FAD-linked oxidoreductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1533 | 0.5 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0077 | 0.1533 | 1 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0321 | 1 | 1 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0033 | 0 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0077 | 0.1533 | 0.1533 |
Mycobacterium ulcerans | oxidoreductase GMC-type | 0.0033 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0033 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0033 | 0 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0207 | 0.6064 | 0.6064 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.1533 | 0.5 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0321 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0207 | 0.6064 | 0.6064 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0077 | 0.1533 | 0.1533 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0186 | 0.5309 | 0.5309 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0199 | 0.5792 | 0.5792 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1533 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0077 | 0.1533 | 0.1533 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0033 | 0 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0077 | 0.1533 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1533 | 0.5 |
Echinococcus granulosus | histone deacetylase 1 | 0.0077 | 0.1533 | 0.1533 |
Schistosoma mansoni | histone deacetylase | 0.0077 | 0.1533 | 0.1533 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.1533 | 0.5 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0321 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.1533 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1533 | 0.5 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0077 | 0.1533 | 0.1533 |
Mycobacterium ulcerans | hypothetical protein | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1533 | 0.5 |
Chlamydia trachomatis | monooxygenase | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0077 | 0.1533 | 0.1533 |
Mycobacterium ulcerans | FAD-dependent oxidoreductase | 0.0033 | 0 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0077 | 0.1533 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1533 | 0.5 |
Giardia lamblia | Histone deacetylase | 0.0077 | 0.1533 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0033 | 0 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1533 | 0.1533 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0186 | 0.5309 | 0.5309 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0077 | 0.1533 | 0.1533 |
Leishmania major | histone deacetylase, putative | 0.0077 | 0.1533 | 0.1533 |
Leishmania major | histone deacetylase, putative | 0.0077 | 0.1533 | 0.1533 |
Plasmodium falciparum | histone deacetylase 1 | 0.0077 | 0.1533 | 1 |
Mycobacterium ulcerans | membrane-associated oxidoreductase | 0.0033 | 0 | 0.5 |
Trypanosoma brucei | histone deacetylase 1 | 0.0077 | 0.1533 | 0.1533 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.