Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0026 | 0.3026 | 0.2944 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0026 | 0.3026 | 0.3438 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0437 | 0.0754 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.1703 | 0.1606 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.1703 | 0.372 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0026 | 0.3026 | 0.2944 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0026 | 0.3026 | 0.2944 |
Schistosoma mansoni | biogenic amine receptor | 0.0026 | 0.3026 | 0.2944 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0026 | 0.3026 | 0.2944 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0026 | 0.3026 | 0.3456 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Brugia malayi | hypothetical protein | 0.0026 | 0.3026 | 0.3456 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0026 | 0.3026 | 0.2944 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.3437 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Brugia malayi | hypothetical protein | 0.0026 | 0.3026 | 0.3456 |
Schistosoma mansoni | amine GPCR | 0.0026 | 0.3026 | 0.2944 |
Brugia malayi | sulfakinin receptor protein | 0.0026 | 0.3026 | 0.3456 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0026 | 0.3026 | 0.2944 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0026 | 0.3026 | 0.2944 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0026 | 0.3026 | 0.2944 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.5067 | 0.615 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.7966 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Brugia malayi | Dopamine receptor | 0.0026 | 0.3026 | 0.3456 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.1703 | 0.1704 |
Echinococcus multilocularis | g protein coupled receptor | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.1703 | 0.1606 |
Schistosoma mansoni | opsin-like receptor | 0.0026 | 0.3026 | 0.2944 |
Brugia malayi | Dopamine receptor protein 1 | 0.0026 | 0.3026 | 0.3456 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0 | 0.5 |
Echinococcus granulosus | g protein coupled receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.1703 | 0.1606 |
Schistosoma mansoni | neuropeptide receptor | 0.0026 | 0.3026 | 0.2944 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0026 | 0.3026 | 0.2944 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0026 | 0.3026 | 0.3438 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.1703 | 0.1681 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0026 | 0.3026 | 0.2944 |
Schistosoma mansoni | histamine h1 receptor | 0.0026 | 0.3026 | 0.2944 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0026 | 0.3026 | 0.2944 |
Echinococcus multilocularis | serotonin receptor | 0.0026 | 0.3026 | 0.6819 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.1703 | 0.1704 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | g protein coupled receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.1703 | 0.372 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.3437 | 0.5 |
Brugia malayi | hypothetical protein | 0.0026 | 0.3026 | 0.3456 |
Brugia malayi | larval opioid receptor | 0.0026 | 0.3026 | 0.3456 |
Echinococcus granulosus | orexin receptor type 2 | 0.0026 | 0.3026 | 0.6819 |
Brugia malayi | hypothetical protein | 0.0026 | 0.3026 | 0.3456 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0026 | 0.3026 | 0.2944 |
Schistosoma mansoni | amine GPCR | 0.0026 | 0.3026 | 0.2944 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | hypothetical protein | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | hypothetical protein | 0.0026 | 0.3026 | 0.2944 |
Brugia malayi | hypothetical protein | 0.0018 | 0.1795 | 0.1826 |
Brugia malayi | Serotonin receptor | 0.0026 | 0.3026 | 0.3456 |
Brugia malayi | neuropeptide F receptor | 0.0026 | 0.3026 | 0.3456 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.1703 | 0.372 |
Echinococcus multilocularis | somatostatin receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0026 | 0.3026 | 0.6819 |
Brugia malayi | hypothetical protein | 0.0026 | 0.3026 | 0.3456 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0026 | 0.3026 | 0.3438 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0026 | 0.3026 | 0.6819 |
Onchocerca volvulus | 0.0032 | 0.4082 | 1 | |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0026 | 0.3026 | 0.3456 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0026 | 0.3026 | 0.2944 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0026 | 0.3026 | 0.3456 |
Echinococcus granulosus | serotonin receptor | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | opsin-like receptor | 0.0026 | 0.3026 | 0.2944 |
Brugia malayi | hypothetical protein | 0.0028 | 0.3437 | 0.4001 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | neuropeptide receptor | 0.0026 | 0.3026 | 0.2944 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.3437 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | neuropeptide s receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0026 | 0.3026 | 0.2944 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0026 | 0.3026 | 0.2944 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0026 | 0.3026 | 0.3438 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0026 | 0.3026 | 0.6819 |
Brugia malayi | Serotonin receptor | 0.0026 | 0.3026 | 0.3456 |
Brugia malayi | hypothetical protein | 0.0026 | 0.3026 | 0.3456 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0026 | 0.3026 | 0.2944 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0026 | 0.3026 | 0.3456 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0026 | 0.3026 | 0.2944 |
Echinococcus granulosus | somatostatin receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | serotonin receptor | 0.0026 | 0.3026 | 0.6819 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0 | 0.5 |
Brugia malayi | putative neuropeptide receptor | 0.0026 | 0.3026 | 0.3456 |
Echinococcus multilocularis | g protein coupled receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0026 | 0.3026 | 0.2944 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Brugia malayi | hypothetical protein | 0.0026 | 0.3026 | 0.3456 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus multilocularis | fmrfamide receptor | 0.0026 | 0.3026 | 0.6819 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0026 | 0.3026 | 0.3456 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.8804 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0026 | 0.3026 | 0.3456 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0026 | 0.3026 | 0.2944 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | adenoreceptor | 0.0026 | 0.3026 | 0.2944 |
Echinococcus granulosus | neuropeptide receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0026 | 0.3026 | 0.2944 |
Brugia malayi | ORL1-like opioid receptor | 0.0026 | 0.3026 | 0.3456 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | g protein coupled receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.7966 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.4383 | 0.4318 |
Echinococcus multilocularis | g protein coupled receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0026 | 0.3026 | 0.3438 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.7966 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.4383 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4082 | 0.4013 |
Echinococcus granulosus | neuropeptide receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0026 | 0.3026 | 0.3438 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.4082 | 0.4856 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0026 | 0.3026 | 0.6819 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0 | 0.5 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0026 | 0.3026 | 0.3456 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0026 | 0.3026 | 0.3438 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus multilocularis | neuropeptide receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus multilocularis | neuropeptide receptor | 0.0026 | 0.3026 | 0.6819 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0026 | 0.3026 | 0.3456 |
Brugia malayi | Melatonin receptor type 1A | 0.0026 | 0.3026 | 0.3456 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0026 | 0.3026 | 0.2944 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.4082 | 0.4842 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | hypothetical protein | 0.0026 | 0.3026 | 0.2944 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | neuropeptide receptor | 0.0026 | 0.3026 | 0.2944 |
Brugia malayi | follicle stimulating hormone receptor | 0.0026 | 0.3026 | 0.3456 |
Brugia malayi | GnHR receptor homolog | 0.0026 | 0.3026 | 0.3456 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.5067 | 0.616 |
Schistosoma mansoni | amine GPCR | 0.0026 | 0.3026 | 0.2944 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.4383 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.3437 | 0.3984 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0026 | 0.3026 | 0.2944 |
Echinococcus granulosus | fmrfamide receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.4383 | 0.4318 |
Schistosoma mansoni | myosin xvIII | 0.0026 | 0.3026 | 0.2944 |
Schistosoma mansoni | hypothetical protein | 0.0026 | 0.3026 | 0.2944 |
Brugia malayi | Dopamine receptor protein 2 | 0.0026 | 0.3026 | 0.3456 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus granulosus | allatostatin A receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.3437 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.1703 | 0.1681 |
Brugia malayi | G-protein coupled receptor | 0.0026 | 0.3026 | 0.3456 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | g-protein coupled receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | amine GPCR | 0.0026 | 0.3026 | 0.2944 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0026 | 0.3026 | 0.3438 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0026 | 0.3026 | 0.3456 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0026 | 0.3026 | 0.3438 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0026 | 0.3026 | 0.6819 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.3437 | 0.5 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0026 | 0.3026 | 0.2944 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.7966 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0026 | 0.3026 | 0.3456 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Brugia malayi | G protein-coupled receptor | 0.0026 | 0.3026 | 0.3456 |
Schistosoma mansoni | biogenic amine receptor | 0.0026 | 0.3026 | 0.2944 |
Brugia malayi | hypothetical protein | 0.0026 | 0.3026 | 0.3456 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0026 | 0.3026 | 0.6819 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.1703 | 0.372 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | neuropeptide receptor | 0.0026 | 0.3026 | 0.2944 |
Brugia malayi | G-protein coupled receptor | 0.0026 | 0.3026 | 0.3456 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0026 | 0.3026 | 0.2944 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | sex peptide receptor | 0.0026 | 0.3026 | 0.6819 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0026 | 0.3026 | 0.2944 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0026 | 0.3026 | 0.6819 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0026 | 0.3026 | 0.3456 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0 | 0.5 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0026 | 0.3026 | 0.2944 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0882 | 0.0776 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.5067 | 0.501 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Schistosoma mansoni | hypothetical protein | 0.0026 | 0.3026 | 0.2944 |
Brugia malayi | RE15519p | 0.0026 | 0.3026 | 0.3456 |
Brugia malayi | AKH receptor | 0.0026 | 0.3026 | 0.3456 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0 | 0.5 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0013 | 0.0882 | 0.1796 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0026 | 0.3026 | 0.6819 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus multilocularis | allatostatin A receptor | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0026 | 0.3026 | 0.2944 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | amine GPCR | 0.0026 | 0.3026 | 0.2944 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0026 | 0.3026 | 0.2944 |
Echinococcus multilocularis | sex peptide receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0437 | 0.0754 |
Echinococcus multilocularis | fmrfamide receptor | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.1703 | 0.372 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3026 | 0.3438 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.1703 | 0.372 |
Schistosoma mansoni | biogenic amine receptor | 0.0026 | 0.3026 | 0.2944 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.3437 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0026 | 0.3026 | 0.2944 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.1703 | 0.1606 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.3437 | 0.5 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0 | 0.5 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0026 | 0.3026 | 0.6819 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0013 | 0.0882 | 0.1796 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0026 | 0.3026 | 0.6819 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0026 | 0.3026 | 0.6819 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0026 | 0.3026 | 0.2944 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 14.9 % | Induction of monoastral spindles in HeLa cells at 100 uM after 7 hrs | ChEMBL. | 17587586 |
Activity (functional) | = 14.9 % | Induction of monoastral spindles in HeLa cells at 100 uM after 7 hrs | ChEMBL. | 17587586 |
Activity (functional) | < 25 % | Induction of monoastral spindles in HeLa cells at 50 uM after 7 hrs | ChEMBL. | 17587586 |
Activity (functional) | < 25 % | Induction of monoastral spindles in HeLa cells at 50 uM after 7 hrs | ChEMBL. | 17587586 |
IC50 (functional) | 0 | Induction of monoastral spindles in HeLa cells after 7 hrs | ChEMBL. | 17587586 |
IC50 (functional) | = 39 uM | Inhibition of Eg5 ATPase activity expressed in Escherichia coli after 12 hrs | ChEMBL. | 17587586 |
IC50 (functional) | = 39 uM | Inhibition of Eg5 ATPase activity expressed in Escherichia coli after 12 hrs | ChEMBL. | 17587586 |
IC50 (functional) | = 69.1 uM | Inhibition of microtubule-stimulated Eg5 ATPase activity expressed in Escherichia coli after 12 hrs | ChEMBL. | 17587586 |
IC50 (functional) | = 69.1 uM | Inhibition of microtubule-stimulated Eg5 ATPase activity expressed in Escherichia coli after 12 hrs | ChEMBL. | 17587586 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.